CN109855941A - Dip dyeing formula dyeing instrument - Google Patents

Dip dyeing formula dyeing instrument Download PDF

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Publication number
CN109855941A
CN109855941A CN201910186247.XA CN201910186247A CN109855941A CN 109855941 A CN109855941 A CN 109855941A CN 201910186247 A CN201910186247 A CN 201910186247A CN 109855941 A CN109855941 A CN 109855941A
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CN
China
Prior art keywords
axis
reagent
dyeing
sample
luggage carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910186247.XA
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Chinese (zh)
Inventor
孙西钊
李帅
臧蒙
王震
马美丽
胡付余
聂垒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANGHAI HAWSOME BIOTECHNOLOGY Co Ltd
Original Assignee
SHANGHAI HAWSOME BIOTECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by SHANGHAI HAWSOME BIOTECHNOLOGY Co Ltd filed Critical SHANGHAI HAWSOME BIOTECHNOLOGY Co Ltd
Priority to CN201910186247.XA priority Critical patent/CN109855941A/en
Publication of CN109855941A publication Critical patent/CN109855941A/en
Pending legal-status Critical Current

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Abstract

The present invention provides a kind of dip dyeing formula dyeing instruments, including braced frame, luggage carrier, tri- shaft moving device of XYZ and material boom, tri- shaft moving device of XYZ is set to braced frame top drive material boom to realize the movement of material frame, the luggage carrier is located at the bottom of braced frame, the luggage carrier is equipped with the several columns for putting feeding rack and places position, and several columns placement position is divided into sample placement to be contaminated position, reagent places position and sample placement position is completed in dyeing.The present invention compensates for because bring hand-manipulated is inconvenient and be easy the disadvantage of pollution, while when handling a large amount of micro-biological samples, easily operated, saves reagent cost, pollution caused by avoiding microbiological manipulations improper.

Description

Dip dyeing formula dyeing instrument
Technical field
The present invention relates to bio-instruments technical fields, and in particular, to a kind of full-automatic dip dyeing formula dyeing instrument.
Background technique
Quickly, laboratory is also developed to automatic technology for present clinical treatment measuring means technology innovation.
In experimental implementation, manual operation can bring experimental error, inefficiency, and result hand-manipulated varies with each individual, is difficult Guarantee the accuracy and timeliness of clinical sample Micro biological Tests.Such as cause the experiment knot of a large amount of false positive and false negative Fruit not can guarantee the quality of experiments in laboratory, while manual experimental implementation can also cause the unnecessary waste of test reagent, to real It tests room and brings more economic losses, increase the discharge of laboratory harmful reagent.In addition, microbiological manipulations are improper also to bring ring Border pollution, it is well known that microorganism can cause to test as 2 grades of biological safety level of biological pests, unsuitable operation Chamber contamination even pollution of some pathogenic bacteria for lab assistant, leads to bigger casualties or economic loss.
For existing dyeing instrument mainly based on craft, there is dyeing effect in the method that dyeing instrument mainly uses spray-painting or drop dye The disadvantages of fruit disunity, differences between batches are big, and sample is insufficient in conjunction with reagent.
By the retrieval to the prior art, application No. is 200920140796.5 utility models to disclose a kind of slide dye Color device including shadoof and is connected at least one bracket of shadoof bottom end, which is connected up and down, is connected on inner sidewall There are at least two pieces of identical elongate support plates, is uniformly dispersed on the upper surface of this two pieces of support plates symmetrical multiple The rectangle card slot of slide is supported, every two is identical with respect to the size of card slot, shape and depth.The defect of above-mentioned dyeing apparatus It is that dyeing liquor dosage, dyeing time need to operate by hand, there are dyeing effect disunities, and differences between batches are big, sample and reagent knot Close insufficient problem.
Summary of the invention
For the defects in the prior art, the object of the present invention is to provide a kind of dip dyeing formula dyeing instruments.
A kind of dip dyeing formula dyeing instrument provided according to the present invention, including braced frame, luggage carrier, tri- shaft moving device of XYZ With material boom, tri- shaft moving device of XYZ realizes the movement of material frame set on braced frame top drive material boom, described Luggage carrier is located at the bottom of braced frame, and the luggage carrier is equipped with the several columns for putting feeding rack and places position, described several Column placement position is divided into sample placement to be contaminated position, reagent places position and sample placement position is completed in dyeing.
Further, tri- shaft moving device of XYZ includes X-axis motor, y-axis motor and Z axis motor, the y-axis motor It is connected between Z axis motor by Y-axis slide plate, Y-axis slide plate bottom is equipped with Y-axis sliding rail, and the Y-axis sliding rail and setting are even The Y-axis sliding slot cooperation for connecing square tube upper surface realizes that the Y-direction of material boom is mobile, and one end of the X-axis motor and connecting square pipes is fixed, The lower surface both ends of the connecting square pipes are respectively provided with one piece of X-axis slide plate, and the bottom of the X-axis slide plate is equipped with X-axis sliding slot, the X Axis sliding slot cooperates with the X-axis slide rail being arranged at the top of braced frame realizes the X for expecting boom to movement, the lower section of the Z axis motor It is controlled by screw structure binder boom to move up and down along Z axis.
Further, one end of the X-axis sliding slot is equipped with X-axis limiter.
Further, the bottom of the X-axis slide plate is set there are two X-axis slide rail.
Further, the material boom includes vertical linking arm and " h " shape suspender for hanging hanging frame, described " h " Shape suspender is rotated by 90 ° horizontal positioned rear upper part horizontal segment end counterclockwise and fixes with vertical linking arm, and lower horizontal is used In outstanding hanging frame.
Further, the material frame includes two rows of slide sample slots disposed in parallel and two outstanding hooks, described two outstanding hooks The top left and right ends of slide sample slot are oppositely arranged on, the length of the lower horizontal of " h " the shape suspender is greater than described The distance between two outstanding hooks.
Further, the every row of the slide sample slot is arranged 25.
Further, the placement position on the luggage carrier is the groove body that is downwardly extending of bottom, under the luggage carrier Side is equipped with pedestal, and the height between the bottom and luggage carrier of the pedestal is greater than the depth of the groove body.
Further, reagent placement position is at least two rows of, and each reagent, which is placed, is equipped with reagent basin, the reagent in position Basin has reagent entry port and reagent exit, and the reagent basin is connected by pipeline and pump.
Further, the sample to be contaminated places position and dyeing completes sample placement position and respectively has a column, each column sample to be contaminated It places position and dyeing completes sample to place position to be 4, the reagent, which places position, 2 column, and each column reagent, which places position, 3.
Compared with prior art, the present invention have it is following the utility model has the advantages that
1, tri- shaft moving device of XYZ realizes the accurate movement of material frame, and coloration result is good, the consistency of experimental result and can Reproducibility is conducive to program standardization and operates;It compensates for because of the disadvantage of bring inconvenience hand-manipulated and easy pollution, simultaneously It is easily operated when handling a large amount of micro-biological samples, save reagent cost, pollution caused by avoiding microbiological manipulations improper.
2, by mechanically actuated, it is not necessarily to human intervention, sample flux is big, and reagent dyeing is abundant, saves reagent.
Detailed description of the invention
Upon reading the detailed description of non-limiting embodiments with reference to the following drawings, other feature of the invention, Objects and advantages will become more apparent upon:
Fig. 1 is perspective view one of the invention;
Fig. 2 is perspective view two of the invention;
Fig. 3 is the structural schematic diagram that the present invention places position;
Fig. 4 is the structural schematic diagram (not putting slide) of present invention material frame;
Fig. 5 is the structural schematic diagram (placing slide) of present invention material frame;
Fig. 6 is the structural schematic diagram of reagent basin of the present invention;
Fig. 7 is the structural schematic diagram of the mobile device of tri- axis of XYZ.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field For personnel, without departing from the inventive concept of the premise, several changes and improvements can also be made.These belong to the present invention Protection scope.
As shown in Figures 1 to 7, a kind of dip dyeing formula dyeing instrument, including braced frame 1, luggage carrier 2, tri- shaft moving device of XYZ 3 are set to 1 top drive material boom 4 of braced frame with material boom 4, tri- shaft moving device 3 of XYZ to realize the movement of material frame 5.
Expect that frame 5 includes two rows of slide sample slots 51 disposed in parallel and two outstanding hooks 52, the every row of slide sample slot 51 setting 25, two outstanding hooks 52 are oppositely arranged on the top left and right ends of slide sample slot.
Expect that boom 4 includes vertical linking arm 41 and " h " the shape suspender 42 for hanging hanging frame, " h " shape suspender 42 is inverse Hour hands are rotated by 90 ° horizontal positioned rear 421 end of upper part horizontal segment and vertical linking arm 41 is fixed, and lower horizontal 422 is used for Two outstanding hooks 52 on outstanding hanging frame 5, the length of the lower horizontal 422 of " h " shape suspender is outstanding greater than two on material frame to hook 52 The distance between, facilitate stable movement after hanging frame can be hanged, while being to guarantee that material frame is not fallen in weak vibrations material frame.
Luggage carrier 2 is equipped with four column for putting feeding rack 5 and places position, is followed successively by one from left to right and arranges sample placement to be contaminated 21, two column reagents of position place position 22 and a column dyeing completes sample and places position 23.Each column sample to be contaminated places position and dyeing is completed It is 4 that sample, which places position, and each column reagent, which places position, 3.Each reagent, which is placed, is equipped with reagent basin 24, reagent basin 24 in position 22 There are reagent entry port 241 and reagent exit 242, reagent basin 24 is connected by pipeline and pump, and reagent needed for supplementing into reagent basin leads to Reagent exit discharge reagent waste liquid is crossed, is toppled over without lifting reagent basin, it is time saving and energy saving.
Luggage carrier 2 is located at the bottom of braced frame 1, and the placement position on luggage carrier 2 is the groove body that bottom is downwardly extending, The lower section of luggage carrier is equipped with pedestal 6, and the height between the bottom and luggage carrier 2 of pedestal is greater than the depth of groove body, makes groove body will not Ground or test table top are touched, guarantees that groove body by collision cleft or will not crash and influence to test.
Tri- shaft moving device 3 of XYZ includes X-axis motor 31, y-axis motor 32 and Z axis motor 33, y-axis motor 32 and Z axis motor It is connected between 33 by Y-axis slide plate 34,34 bottom of Y-axis slide plate is equipped with Y-axis sliding rail 341, and Y-axis sliding rail 341 and setting are in connection side The Y-axis sliding slot 351 of 35 upper surface of pipe cooperates, and realizes that the Y-direction movement of material boom 4 (passes through rack-and-pinion by the control of y-axis motor Or other transmission mechanisms make motor drive material boom Y-direction mobile), X-axis motor 31 and one end of connecting square pipes 35 are fixed, connection side The lower surface both ends of pipe 35 are respectively provided with one piece of X-axis slide plate 36, and the bottom of X-axis slide plate 36 sets that there are two X-axis sliding slots 361, Ke Yibao The X of card material frame is high to mobile accuracy, and too large deviation, X-axis sliding slot 361 and the X-axis that 1 top of braced frame is arranged in will not occur The cooperation of sliding rail 37 realizes the X of material boom 4 to movement, and one end of X-axis slide rail 37 is equipped with X-axis limiter 38, prevents material boom 4 from skidding off Sliding slot influences operation, and the lower section of Z axis motor 33 controls it by 331 binder boom 4 of screw structure and moves up and down along Z axis.
The course of work is as follows:
(1) it is mobile to carry out X, Y-direction for the X-axis motor in tri- shaft moving device of XYZ and y-axis motor control material boom, reach to Color card places position, and " h " shape suspender of material boom bottom tangles the outstanding hook of material frame, under the control of Z axis motor, expects boom Lift the material frame equipped with the slide sample 39 that need to be dyed to rise, is then moved to the reagent closed on and places position, reagent basin therein In be equipped with reagent 1;
(2) etc. the dyeing time that candidate agents 1 need, tri- shaft moving device of XYZ slightly drives material frame shaking while waiting, Increase the combination of reagent and slide sample;
(3) after 1 dyeing time of candidate agent, tri- shaft moving device of XYZ will expect that frame is moved to other column reagent and places , reagent 2 is housed in reagent basin therein;
(4) the above steps are repeated, until staining procedure terminates, tri- shaft moving device of XYZ will expect that frame is moved to dyeing and completes Sample places position.
In the description of the present application, it is to be understood that term " on ", "front", "rear", "left", "right", " is erected at "lower" Directly ", the orientation or positional relationship of the instructions such as "horizontal", "top", "bottom", "inner", "outside" is orientation based on the figure or position Relationship is set, description the application is merely for convenience of and simplifies description, rather than the device or element of indication or suggestion meaning are necessary It with specific orientation, is constructed and operated in a specific orientation, therefore should not be understood as the limitation to the application.
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned Particular implementation, those skilled in the art can make a variety of changes or modify within the scope of the claims, this not shadow Ring substantive content of the invention.In the absence of conflict, the feature in embodiments herein and embodiment can any phase Mutually combination.

Claims (10)

1. a kind of dip dyeing formula dyeing instrument, which is characterized in that including braced frame, luggage carrier, tri- shaft moving device of XYZ and material frame Arm, tri- shaft moving device of XYZ are set to braced frame top drive material boom to realize the movement of material frame, the luggage carrier Positioned at the bottom of braced frame, the luggage carrier is equipped with the several columns for putting feeding rack and places position, and the several columns are placed Position is divided into sample placement to be contaminated position, reagent places position and dyeing completes sample and places position.
2. dip dyeing formula dyeing instrument according to claim 1, which is characterized in that tri- shaft moving device of XYZ includes X-axis electricity Machine, y-axis motor and Z axis motor, are connected between the y-axis motor and Z axis motor by Y-axis slide plate, and Y-axis slide plate bottom is set There is Y-axis sliding rail, the Y-axis sliding rail realizes that the Y-direction of material boom is mobile with the Y-axis sliding slot cooperation that connecting square pipes upper surface is arranged in, One end of the X-axis motor and connecting square pipes is fixed, and the lower surface both ends of the connecting square pipes are respectively provided with one piece of X-axis slide plate, institute The bottom for stating X-axis slide plate is equipped with X-axis sliding slot, and the X-axis sliding slot realizes material with the X-axis slide rail cooperation being arranged at the top of braced frame The X of boom controls it by screw structure binder boom and moves up and down along Z axis to movement, the lower section of the Z axis motor.
3. dip dyeing formula dyeing instrument according to claim 2, which is characterized in that one end of the X-axis sliding slot is limited equipped with X-axis Device.
4. dip dyeing formula dyeing instrument according to claim 2, which is characterized in that the bottom of the X-axis slide plate is set there are two X-axis Sliding rail.
5. dip dyeing formula dyeing instrument according to claim 1, which is characterized in that the material boom includes vertical linking arm and use In " h " shape suspender of outstanding hanging frame, " h " the shape suspender is rotated by 90 ° horizontal positioned rear upper part horizontal segment end counterclockwise End is fixed with vertical linking arm, and lower horizontal is for hanging hanging frame.
6. dip dyeing formula dyeing instrument according to claim 5, which is characterized in that the material frame includes two rows of glass disposed in parallel Piece sample slot and two outstanding hooks, described two outstanding hooks are oppositely arranged on the top left and right ends of slide sample slot, and " h " shape is outstanding The length of the lower horizontal of pendant is greater than the distance between described two outstanding hooks.
7. dip dyeing formula dyeing instrument according to claim 6, which is characterized in that the every row of slide sample slot is arranged 25.
8. dip dyeing formula dyeing instrument according to claim 1, which is characterized in that placement position on the luggage carrier be bottom to Under the groove body that extends to form, the lower section of the luggage carrier is equipped with pedestal, and the height between the bottom and luggage carrier of the pedestal is big In the depth of the groove body.
9. dip dyeing formula dyeing instrument according to claim 1, which is characterized in that reagent placement position is at least two rows of, often A reagent is placed and is equipped with reagent basin in position, and the reagent basin has a reagent entry port and reagent exit, the reagent basin by pipeline and Pump connection.
10. dip dyeing formula dyeing instrument according to claim 1, which is characterized in that the sample to be contaminated is placed position and dyed Placing position at sample respectively has a column, and each column sample to be contaminated places position and dyeing completes sample to place position to be 4, and the reagent is put Set has 2 column, and each column reagent, which places position, 3.
CN201910186247.XA 2019-03-12 2019-03-12 Dip dyeing formula dyeing instrument Pending CN109855941A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910186247.XA CN109855941A (en) 2019-03-12 2019-03-12 Dip dyeing formula dyeing instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910186247.XA CN109855941A (en) 2019-03-12 2019-03-12 Dip dyeing formula dyeing instrument

Publications (1)

Publication Number Publication Date
CN109855941A true CN109855941A (en) 2019-06-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112945684A (en) * 2019-12-10 2021-06-11 镇江蓝勃医疗器械有限公司 Pathological section dyeing machine

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61235734A (en) * 1985-04-12 1986-10-21 Chiyoda Seisakusho:Kk Automatic dyeing device for microscopic specimem
EP1408320A2 (en) * 2002-10-09 2004-04-14 S.A. Francisco Soria Melguizo Programmable automatic system for microbiological, histological and cytological stainings
JP2009293983A (en) * 2008-06-03 2009-12-17 Tabata Engineering:Kk Staining apparatus for slide specimen
CN103884565A (en) * 2014-04-02 2014-06-25 深圳市达科为医疗科技有限公司 Pathological staining machine
CN206945405U (en) * 2017-06-30 2018-01-30 迈克医疗电子有限公司 Sample processing apparatus
CN207649986U (en) * 2018-01-02 2018-07-24 佛山市艾达思精密仪器有限公司 A kind of Full-automatic slice-dyeing machine
CN209927565U (en) * 2019-03-12 2020-01-10 上海皓信生物科技有限公司 Dip dyeing type dyeing instrument

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61235734A (en) * 1985-04-12 1986-10-21 Chiyoda Seisakusho:Kk Automatic dyeing device for microscopic specimem
EP1408320A2 (en) * 2002-10-09 2004-04-14 S.A. Francisco Soria Melguizo Programmable automatic system for microbiological, histological and cytological stainings
JP2009293983A (en) * 2008-06-03 2009-12-17 Tabata Engineering:Kk Staining apparatus for slide specimen
CN103884565A (en) * 2014-04-02 2014-06-25 深圳市达科为医疗科技有限公司 Pathological staining machine
CN206945405U (en) * 2017-06-30 2018-01-30 迈克医疗电子有限公司 Sample processing apparatus
CN207649986U (en) * 2018-01-02 2018-07-24 佛山市艾达思精密仪器有限公司 A kind of Full-automatic slice-dyeing machine
CN209927565U (en) * 2019-03-12 2020-01-10 上海皓信生物科技有限公司 Dip dyeing type dyeing instrument

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112945684A (en) * 2019-12-10 2021-06-11 镇江蓝勃医疗器械有限公司 Pathological section dyeing machine
CN112945684B (en) * 2019-12-10 2022-11-29 镇江蓝勃医疗器械有限公司 Pathological section dyeing machine

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