CN109620155A - A kind of high-accuracy self-adaptation physiology signal tester and test method - Google Patents

A kind of high-accuracy self-adaptation physiology signal tester and test method Download PDF

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Publication number
CN109620155A
CN109620155A CN201811591619.9A CN201811591619A CN109620155A CN 109620155 A CN109620155 A CN 109620155A CN 201811591619 A CN201811591619 A CN 201811591619A CN 109620155 A CN109620155 A CN 109620155A
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CN
China
Prior art keywords
signal
circuit module
resistance
amplification
circuit
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CN201811591619.9A
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Chinese (zh)
Inventor
韩磊
郎平
姚璐
宋钦昊
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北京理工大学
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Priority to CN2018110897897 priority
Application filed by 北京理工大学 filed Critical 北京理工大学
Publication of CN109620155A publication Critical patent/CN109620155A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/725Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00Computer-aided design [CAD]
    • G06F30/30Circuit design
    • G06F30/39Circuit design at the physical level
    • G06F30/392Floor-planning or layout, e.g. partitioning or placement

Abstract

The present invention relates to a kind of high-accuracy self-adaptation physiology signal tester and test methods, its PCB circuit board (15) is provided with wiring region (10), BNC connector (11), signal gating switch (12), signal amplification factor adjusting knob (13), and shielding shell (7) sets sensor circuit signal input end hole (1), signal testing output stomidium (2), positive supply stomidium (3) etc.;PCB circuit board (15) is placed in shielding shell (7), and the circuit connection of PCB circuit board (15) and the port signal I/O and BNC connector (11), signal gating switch (12), signal amplification factor adjusting knob (13) pass through sensor circuit signal input end hole (1), signal testing output stomidium (2), positive supply stomidium (3) in shielding shell (7) etc. and draw and connect with external equipment.The tester can not only realize record and the data processing of physiology signal, and signal detection and the precision of processing are high.

Description

A kind of high-accuracy self-adaptation physiology signal tester and test method

Technical field

The present invention relates to signal detections and processing technology field, and in particular to a kind of high-accuracy self-adaptation physiology signal Tester and test method.

Background technique

Physiology signal is bio signal intrinsic in human body, including electrocardio, brain electricity, myoelectricity, pulse, heart sound, borborygmus Equal signals clinically often using physiology signal as the important method of patient disease Clinics and Practices, accurately measure people Body physiological signal plays a crucial role patient disease Clinics and Practices.Physiology signal is a kind of ultralow frequency, pole Its small-signal, frequency is generally 30Hz or less, amplitude is 10-3 grades hereinafter, being often submerged under strong noise background.Face On bed, need to be submerged in physiology signal in very noisy accurately detected, analyze with identification.In strong noise background environment Under, accurate extraction physiology signal is extremely difficult.

The Chinese utility model patent of Publication No. CN204119200U discloses a kind of Weak Signal Detection System, it is wrapped Include add circuit, pure resistance bleeder circuit, Weak Signal Detecting Circuit, single-chip microcontroller and display circuit, add circuit is by sine wave Signal and noise signal are mixed and are exported to pure resistance bleeder circuit, and pure resistance bleeder circuit is by mixed signal peak Value is decayed and is exported to Weak Signal Detecting Circuit, and Weak Signal Detecting Circuit divides sine wave signal from mixed signal It separates out and carrys out and be delivered to single-chip microcontroller, the digital signal of conversion is delivered to display circuit by monolithic.Publication No. CN204633728U Chinese utility model patent disclosed in apparatus for detecting weak signal by adder U1, bandpass filter, phase-sensitive detector U6, move Phase device, low-pass filter U7 and single-chip microcontroller and display U5 composition, by generating superposed signal in adder, by bandpass filtering Device generates filtering signal, and generates demodulated signal by phase-sensitive detector with phase shift signal, and low-pass filtered device obtains required DC component;The device debugging is convenient, dynamic range is big.The Chinese utility model patent of Publication No. CN204595048U discloses Apparatus for detecting weak signal include small-signal monitoring modular, locking phase amplification realize module, central processing module and display mould Block realizes that module carries out preset and control to signal by multiplicative principle using central processing module and locking phase amplification.

Existing method for detecting weak signals precision is low, signal-to-noise ratio is low, detection method is single, accurate to physiology signal Detection brings certain difficulty with analysis.Therefore it needs to research and develop a kind of high-accuracy self-adaptation physiology signal tester, realizes It is of great significance to the accurate detection of physiology signal under strong noise background environment.

Summary of the invention

For solving the skills such as current method for detecting weak signals detection accuracy is low, detection method is cumbersome, instrument price is expensive Art problem, the present invention provide good a kind of high-precision, stability, strong interference immunity, low noise, it is easy to operate, cheap from Adapt to physiology signal tester and test method, can high-precision, low noise, stably measured physiology signal, realization The record of such signal and data processing, to improve signal detection and processing accuracy.

To achieve the goals above, the present invention adopts the following technical scheme that.

Firstly, the present invention provides a kind of high-accuracy self-adaptation physiology signal tester, it includes shielding shell and PCB Circuit board specifically includes:

The PCB circuit board is provided with wiring region, BNC connector, signal gating switch and signal amplification factor tune Knob is saved, the wiring region includes that Adaptive matching adjusts circuit module, high impedance signal receiving circuit module, first Grade amplification circuit module, voltage follower circuit module, second level amplification and low-pass filter circuit module, signal inversion amplifying circuit Module, protection circuit module, signal sampling complete circuit module and its circuit connection and the port signal I/O;

Four each devices in corner of the PCB circuit board have a supporting screw and screw ground connection;

Sensor circuit signal input end hole, signal testing output stomidium, positive power source terminal are laid on the shielding shell Hole, ground wire stomidium, negative supply stomidium, reference power source stomidium, signal gating switch hole and signal amplification factor adjusting knob hole;

The PCB circuit board is built in shielding shell and is fixed on shielding enclosure bottom by four supporting screws, described The circuit connection of PCB circuit board and the port signal I/O and BNC connector, signal gating switch, signal amplification factor adjusting knob By shielding shell on sensor circuit signal input end hole, signal testing export stomidium, positive supply stomidium, ground wire stomidium, Negative supply stomidium, reference power source stomidium, signal gating switch hole, signal amplification factor adjusting knob hole are drawn, and are set with outside Standby connection.

Preferably, PCB circuit board, shielding shell, signal amplification factor adjusting knob, signal gating switch are detachable Formula assembly.

In any of the above-described technical solution preferably, the external equipment includes external power supply, sensor and sensor Circuit, recorder and recorder circuit.

In any of the above-described technical solution preferably, the both ends that the Adaptive matching adjusts circuit module are separately connected Sensor circuit and high impedance signal receiving circuit module;It includes that two conversions are logical that the Adaptive matching, which adjusts circuit module, Road, channel 1 and channel 2 and channel switch switch K1, heat dissipating ring S1, first resistor R1, second resistance R2, 3rd resistor R3, One capacitor C1With the second capacitor C2;When sensor is active sensor, switch K1It is switched to channel 1;When sensor is passive biography When sensor, switch K1It is switched to channel 2.

In any of the above-described technical solution preferably, one end connection of the high impedance signal receiving circuit module is adaptive Adjusting circuit module should be matched, the other end connects first order amplification circuit module;The high impedance signal receiving circuit module packet Include high-impedance amplifier Ug1, protection ring P, heat dissipating ring S2, the 4th resistance R4, the 5th resistance R5With third capacitor C3;4th resistance R4 For high-impedance amplifier Ug1Negative feedback resistor;5th resistance R5One end Jie high-impedance amplifier Ug1Normal phase input end, separately One end ground connection;Third capacitor C3Be negative feedback capacity, with the 4th resistance R4It is in parallel;Protection ring P setting receives electricity in high impedance signal Road signal input part and signal output end;Heat dissipating ring S2It is arranged in Ug1Negative feedback loop on.

In any of the above-described technical solution preferably, one end connection high impedance letter of the first order amplification circuit module Number receiving circuit module, the other end connect voltage follower circuit module;The first order amplification circuit module includes the first amplification Device U1, the 6th resistance R6, the 7th resistance R7, the first potentiometer RW1, the 4th capacitor C4;6th resistance R6It connects in the first amplifier U1 Inverting input terminal;7th resistance R7One the first amplifier of end Jie U1Normal phase input end, other end ground connection;First potentiometer RW1It connects In the first amplifier U1Two pins on adjust the multiple of preposition amplification, the 4th capacitor C4With the 7th resistance R7Parallel connection denoising.

In any of the above-described technical solution preferably, the both ends of the voltage follower circuit module are separately connected the first order Amplification circuit module, second level amplification and low-pass filter circuit module;The voltage follower circuit module includes the second amplifier U2The first signal path, the second amplifier U2Inverting input terminal is connect with output end;The letter of first order amplification circuit module output Number positive input voltage follows circuit module.

In any of the above-described technical solution preferably, one end of the second level amplification and low-pass filter circuit module connects Connect voltage follower circuit module, other end connection signal see-saw circuit module;The second level amplification and low-pass filtering electricity Road module includes the second amplifier U2Second signal channel, the 8th resistance R8, the 9th resistance R9, the tenth resistance R10, the second current potential Device RW2, the 5th capacitor C5, the 6th capacitor C6, the 7th capacitor C7;8th resistance R8, the 9th resistance R9It connects in the second amplifier U2The The inverting input terminal in binary signal channel;Tenth resistance R10One the second amplifier U of termination2The normal phase input end in second signal channel, Other end ground connection;Second potentiometer RW2Meet the second amplifier U2The negative-feedback in second signal channel adjusts amplification factor;5th electricity Hold C5With the second potentiometer RW2It is in parallel;6th capacitor C6It connects in the second amplifier U2The output end in second signal channel and the 8th electricity Hinder R8, the 9th resistance R9Between, with the second potentiometer RW2, the 5th capacitor C5Form low-pass filter circuit;7th capacitor C7With the tenth Resistance R10It is in parallel.

In any of the above-described technical solution preferably, one end of the signal inversion amplification circuit module connects the second level Amplification and low-pass filter circuit module, other end connection protection circuit module;The signal inversion amplification circuit module includes the Two amplifier U2Third signal path, eleventh resistor R11, twelfth resistor R12, thirteenth resistor R13, the 8th capacitor C8;The 13 resistance R13It connects in the second amplifier U2Third signal path direction input terminal;Twelfth resistor R12With the 8th capacitor C8 It is in parallel.

In any of the above-described technical solution preferably, the protection circuit module connects respectively receives electricity in high impedance signal Between road module and first order amplification circuit module and tester output end;The protection circuit mould includes protection circuit one and protects Protection circuit two;Protection circuit one between high impedance signal receiving circuit module and first order amplification circuit module includes in parallel First diode D1, the second diode D2;The protection circuit two of tester output end includes the 14th resistance R14, the first voltage-stabiliser tube Dw1, the second voltage-stabiliser tube Dw2;The 9th capacitor C of tester output end parallel connection9

In any of the above-described technical solution preferably, the signal sampling complete circuit Module connection signal reverse phase amplification Circuit module, protection circuit module;The signal sampling complete circuit module includes reference voltage source Uref, the tenth capacitor C10, the 11 capacitor C11, the 12nd capacitor C12, reference voltage source UrefAppropriate electrical potential source is selected according to actual needs;11st capacitor C11, the 12nd capacitor C12Then the other end is grounded access reference voltage input channel in one end in parallel.

In any of the above-described technical solution preferably, the two-sided access protection ring of PCB circuit board, sensor circuit letter Number input, signal testing output are all made of coaxial cable, and coaxial cable passes through BNC connector connection.

The invention also discloses a kind of test methods of high-accuracy self-adaptation physiology signal tester: according to such as taking up an official post The test method of high-accuracy self-adaptation physiology signal tester described in one, comprising:

According to different sensor types, circuit module is adjusted by Adaptive matching and selects different match circuits, is made It obtains Human Physiology electric signal and accurately inputs high impedance signal receiving circuit module, and be converted into weak voltage signals V1;It will be faint Voltage signal V1Amplify to obtain voltage signal V by first order amplification circuit module2;Voltage signal V2By voltage follower circuit Module, second level amplification and low-pass filter circuit module amplify to obtain voltage signal V3;Since high impedance signal receives circuit mould Block, first order amplification circuit module, second level amplification and low-pass filter circuit module are to use anti-phase input, so after amplification Signal V3It needs inverter cricuit module to carry out again reverse phase to amplify, so that final output signal V4With the same phase of input signal, finally Output signal V4Meet the voltage signal of record test request for output;Also, output end accesses signal sampling complete circuit mould Block provides subsequent sampling reference voltage, guarantees signal sampling integrality.

The present invention relates to signal detection and process field, in particular to a kind of high-precision suitable for signal analysis and processing Adaptive physiology signal tester and test method.Compared with prior art, above-mentioned technical proposal of the invention has such as It is lower the utility model has the advantages that

1, it solves matching problem between sensor circuit and signal conditioning circuit, uses Adaptive matching and adjust electricity Road, so that the small-signal of sensor acquisition accurately inputs signal conditioning circuit, to improve signal processing precision.

2, high impedance signal receives circuit input end setting protection ring, and around signal processing circuit surrounding in PCB electricity Circuit board double sided setting protection ring can prevent leakage current and bias current entering signal input disturbance letter in PCB circuit board Number measurement;In addition, the protection ring of PCB circuit board surrounding can prevent extraneous interference signal by signal input and output side into Enter circuit board, to improve the precision of signal measurement.

3, existing low-frequency weak signal tester and test method often select the lower amplifier composition amplification of ratio of precision, filter Wave circuit, this kind tester internal circuit is complicated, test result error is larger, expensive etc., such as lock-in amplifier.In view of This, the present invention provides this high-precision, stablizes, strong interference immunity, low noise, easy to operate, cheap faint letter Number tester and test method, can detect ultralow frequency weak signal, quickly, accurately to realize the record and number of this kind of signal According to processing, to improve the efficiency of signal detection and processing.

Detailed description of the invention

In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention without any creative labor, may be used also for those of ordinary skill in the art To obtain other drawings based on these drawings.

Fig. 1 is a preferred implementation of high-accuracy self-adaptation physiology signal tester according to the invention and test method The physiology signal tester structural schematic diagram of example;

Fig. 2 is real shown in high-accuracy self-adaptation physiology signal tester according to the invention and Fig. 1 of test method Apply the PCB circuit board structural schematic diagram of example;

Fig. 3 is real shown in high-accuracy self-adaptation physiology signal tester according to the invention and Fig. 1 of test method Apply the circuit theory schematic diagram of example;

Fig. 4 is real shown in high-accuracy self-adaptation physiology signal tester according to the invention and Fig. 1 of test method Apply the electrical block diagram of example;

Fig. 5 to Figure 10 is the another of high-accuracy self-adaptation physiology signal tester according to the invention and test method The human pulse experimental results figure of preferred embodiment;

Appended drawing reference:

1, sensor circuit signal input end hole, 2, signal testing output stomidium, 3, positive supply stomidium, 4, ground wire stomidium, 5, negative supply stomidium, 6, reference power source stomidium, 7, shielding shell, 8, signal amplification factor adjusting knob hole, 9, signal gating opens Guan Kong;

10, wiring region, 11, BNC connector, 12, signal gating switch, 13, signal amplification factor adjusting knob, 14, supporting screw, 15, PCB circuit board;

101, Adaptive matching adjusts circuit module, 102, high impedance signal receiving circuit module, 103, first order amplification Circuit module, 104, voltage follower circuit module, 105, second level amplification and low-pass filter circuit module, 106, signal inversion puts Big circuit module, 107, protection circuit module, 108, signal sampling complete circuit module.

Specific embodiment

Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.

Embodiment 1

In order to overcome physiology signal test the problems of in the prior art, the embodiment of the present invention proposes one kind High-accuracy self-adaptation physiology signal tester and test method.

As shown in Figures 1 to 4, high-accuracy self-adaptation physiology signal tester described in the present embodiment includes that shielding is outer Shell 7 and PCB circuit board 15, PCB circuit board 15 are provided with wiring region 10, BNC connector 11, signal gating switch 12 and letter Number amplification factor adjusting knob 13, wiring region 10 include that Adaptive matching adjusts circuit module 101, high impedance signal connects Receive circuit module 102, first order amplification circuit module 103, voltage follower circuit module 104, second level amplification and low-pass filtering Circuit module 105, signal inversion amplification circuit module 106, protection circuit module 107, signal sampling complete circuit module 108 and Its circuit connection and the port signal I/O;Four each devices in corner of PCB circuit board 15 have a supporting screw 14 and screw connects Ground;Shielding shell 7 on be laid with sensor circuit signal input end hole 1, signal testing output stomidium 2, positive supply stomidium 3, String port holes 4, negative supply stomidium 5, reference power source stomidium 6, signal gating switch hole 9 and signal amplification factor adjusting knob hole 8; PCB circuit board 15 is built in shielding shell 7 and is fixed on shielding 7 bottom surface of shell, PCB circuit board 15 by four supporting screws 14 Circuit connection and the port signal I/O and BNC connector 11, signal gating switch 12, signal amplification factor adjusting knob 13 it is logical Cross the sensor circuit signal input end hole 1 shielded on shell 7, signal testing output stomidium 2, positive supply stomidium 3, ground wire stomidium 4, negative supply stomidium 5, reference power source stomidium 6, signal gating switch hole 9, signal amplification factor adjusting knob hole 8 draw and with packet Include the external equipment connection of external power supply, sensor and sensor circuit, recorder and recorder circuit etc.;PCB circuit board 15, Shielding shell 7, signal amplification factor adjusting knob 8, signal gating switch 9 is detachable assembly.

In the tester described in the present embodiment, Adaptive matching adjusts circuit module 101 and is used for matched sensors circuit, will Physiology signal is exported and is accurately input to high impedance signal from sensor circuit and receives in circuit 102, solves sensor Circuit and subsequent conditioning circuit mismatch cause signal energy to lose problem, improve Weak absorption precision.Adaptive matching tune The both ends of section circuit module 101 are separately connected sensor circuit and high impedance signal receiving circuit module 102;Adaptive matching tune Saving circuit module 101 includes that two ALT-CH alternate channels, channel 1 and channel 2 and channel switch switch K1, heat dissipating ring S1, first electricity Hinder R1, second resistance R2, 3rd resistor R3, first capacitor C1With the second capacitor C2;When sensor is active sensor, switch K1 It is switched to channel 1;When sensor is passive sensor, switch K1It is switched to channel 2;This ensure that sensor selection is more The flexibility and adaptability of sample and the measurement of different type physiology signal, while the circuit ensure that sensor output signal It is steadily input to subsequent high impedance signal receiving circuit module 102, solves capacitor because high input impedance accumulates a large amount of charges So that sensor output signal generates a large amount of signal energies losses or cannot be defeated when inputting subsequent high impedance signal reception circuit The problem of entering.

In the tester described in the present embodiment, high impedance signal receiving circuit module 102 is micro- for inputting sensor Weak current, charge signal or voltage signal are accurately converted to weak voltage signals V1, convenient for subsequent conditioning circuit to voltage signal at Reason and analysis.One end connection Adaptive matching of high impedance signal receiving circuit module 102 adjusts circuit module 101, the other end Connect first order amplification circuit module 103;High impedance signal receiving circuit module 102 includes high-impedance amplifier Ug1, protection ring P, heat dissipating ring S2, the 4th resistance R4, the 5th resistance R5With third capacitor C3;4th resistance R4For high-impedance amplifier Ug1It is negative anti- Feed resistance;5th resistance R5One end Jie high-impedance amplifier Ug1Normal phase input end, the other end ground connection;Third capacitor C3It is negative Feedback capacity, with the 4th resistance R4It is in parallel;Protection ring P setting receives circuit signal input and signal output in high impedance signal End prevents the noise signal entering signal of the leakage current of PCB circuit board 15 and the bias current of chip from transmitting circuit, therefore guarantees The accuracy of echo signal measurement, this is extremely critical to high-acruracy survey small-signal;Heat dissipating ring S2It is arranged in Ug1It is negative anti- It is fed back to road, is radiated for component, circuit thermal noise is reduced.

In the tester described in the present embodiment, first order amplification circuit module 103 is used for weak voltage signals V1By The first order amplifies to obtain voltage signal V2, precision that the amplification factor of first order amplification circuit module 103 is handled by concrete signal Depending on demand and circuit structure.One end of first order amplification circuit module 103 connects high impedance signal receiving circuit module 102, The other end connects voltage follower circuit module 104;First order amplification circuit module 103 includes the first amplifier U1, the 6th resistance R6, the 7th resistance R7, the first potentiometer RW1, the 4th capacitor C4;6th resistance R6It connects in the first amplifier U1Inverting input terminal;The Seven resistance R7One the first amplifier of end Jie U1Normal phase input end, other end ground connection;First potentiometer RW1It connects in the first amplifier U1Two pins on adjust the multiple of preposition amplification, the 4th capacitor C4With the 7th resistance R7Parallel connection denoising;The amplifying circuit is only It can be achieved with 1~1000 times of amplification factor in the external suitable potential device of amplifier.

In the tester described in the present embodiment, voltage follower circuit module 104 is amplified for the first order and the second level to be isolated Circuit reduces influencing each other between the amplifying circuit of front and back.The both ends of voltage follower circuit module 104 are separately connected the first order and put Big circuit module 103, second level amplification and low-pass filter circuit module 105;Voltage follower circuit module 104 includes the second amplification Device U2The first signal path, the second amplifier U2Inverting input terminal is connect with output end;First order amplification circuit module 103 is defeated Signal positive input voltage out follows circuit module 104.

In the tester described in the present embodiment, second level amplification and low-pass filter circuit module 105 are used for ultralow frequency electricity Press signal V2Amplify to obtain voltage signal V by low-pass filtering, second level amplifier3.Second level amplification and low-pass filter circuit mould One end of block 105 connects voltage follower circuit module 104, other end connection signal see-saw circuit module 106;It puts the second level Big and low-pass filter circuit module 105 includes the second amplifier U2Second signal channel, the 8th resistance R8, the 9th resistance R9, Ten resistance R10, the second potentiometer RW2, the 5th capacitor C5, the 6th capacitor C6, the 7th capacitor C7;8th resistance R8, the 9th resistance R9It connects In the second amplifier U2The inverting input terminal in second signal channel;Tenth resistance R10One the second amplifier U of termination2Second signal is logical The normal phase input end in road, other end ground connection;Second potentiometer RW2Meet the second amplifier U2The negative-feedback in second signal channel is adjusted Amplification factor;5th capacitor C5With the second potentiometer RW2It is in parallel;6th capacitor C6It connects in the second amplifier U2Second signal channel Output end and the 8th resistance R8, the 9th resistance R9Between, with the second potentiometer RW2, the 5th capacitor C5Form low-pass filtering electricity Road;7th capacitor C7With the tenth resistance R10It is in parallel.The amplifying circuit is put with the first order entire circuit of amplifying circuit co- controlling Big multiple flexibly chooses the amplification factor of Weak Signal Processing.

In the tester described in the present embodiment, signal inversion amplification circuit module 106 is used for amplified signal V3Into Row reverse phase amplification, so that final output signal V4With the same phase of input signal, final output signal V4Test request is recorded to meet Voltage signal.One end connection second level amplification of signal inversion amplification circuit module 106 and low-pass filter circuit module 105, Other end connection protection circuit module 107;Signal inversion amplification circuit module 106 includes the second amplifier U2Third signal it is logical Road, eleventh resistor R11, twelfth resistor R12, thirteenth resistor R13, the 8th capacitor C8;Thirteenth resistor R13It connects and is put second Big device U2Third signal path direction input terminal;Twelfth resistor R12With the 8th capacitor C8It is in parallel;It is preposition due to front Current-voltage conversion circuit module, first order amplification circuit module, second level amplification and low-pass filter circuit module are to use Anti-phase input, therefore finally need to access signal inversion modular circuit and come so that entire circuit outputs and inputs same phase.

In the tester described in the present embodiment, protection circuit module 107 is protected for circuit input, the overcurrent of output, over-voltage Shield.Protection circuit module 107 connect respectively high impedance signal receiving circuit module 102 and first order amplification circuit module 103 it Between and tester output end;Protecting circuit module 107 includes protection circuit one and protection circuit two;High impedance signal receives circuit Protection circuit one between module 102 and first order amplification circuit module 103 includes first diode D in parallel1, the two or two pole Pipe D2;The protection circuit two of tester output end includes the 14th resistance R14, the first voltage-stabiliser tube Dw1, the second voltage-stabiliser tube Dw2;Separately Outside, enter tester, the 9th capacitor C of tester output end parallel connection to filter out extraneous noise9

In the tester described in the present embodiment, signal sampling complete circuit module 108 is for providing follow-up signal sampling base Quasi- voltage guarantees the integrality of signal sampling.108 connection signal see-saw circuit module of signal sampling complete circuit module 106, circuit module 107 is protected;Signal sampling complete circuit module 108 includes reference voltage source Uref, the tenth capacitor C10, the tenth One capacitor C11, the 12nd capacitor C12, reference voltage source UrefAppropriate electrical potential source is selected according to actual needs;It makes an uproar to filter out power supply Sound, the 11st capacitor C11, the 12nd capacitor C12Then the other end is grounded access reference voltage input channel in one end in parallel, the circuit It ensure that the integrality of subsequent A/D sample circuit acquisition signal.

In the tester described in the present embodiment, the two-sided access protection ring of PCB circuit board 15, sensor circuit signal input, Signal testing output is all made of coaxial cable, and coaxial cable is connected by BNC connector 11.The signal processing circuit board of tester is double Protection ring is accessed in face, so that signal processing circuit is enclosed in inside protection ring, prevents extraneous interference signal from inputting by signal End and output end enter inside circuit, improve circuit anti-interference.In addition, signal, which is output and input, is all made of coaxial cable, subtract The interference of few outer bound pair signal.

The PCB circuit board structure of the present embodiment is further illustrated in conjunction with Fig. 1 and Fig. 2: in order to PCB circuit board it is easy to assembly and Enhance function of shielding, as shown in Fig. 2, a screw and screw ground connection are respectively loaded onto PCB circuit board quadrangle, PCB circuit board is placed on In shielding shell and it is screwed in shielding enclosure bottom;Simultaneously by inside PCB circuit board wiring and I/O mouthfuls of signal from screen The hole covered on shell extracts, during the test do not have to open shell, convenient for be directly connected to external power supply, sensor circuit and Recorder circuit etc..Meanwhile by signal gating switch and the external shielding shell of amplification factor adjusting knob, it can thus facilitate choosing Signal path and flexible modulation signal amplification factor are selected, as shown in Figure 1, improving test job efficiency.PCB electricity inside tester The each sections such as road plate, shielding shell, gating switch and amplification factor adjusting knob are detachably assembled, and overall structure is simply convenient for grasping To make, sheathing material is made using aluminum material, and shell is light, and tester is portable, and uses common electrical component, at This is low, and tester power supply is ± 3V~± 12V, low-power consumption.

According to high-accuracy self-adaptation physiology signal tester as described above, test method includes:

According to different sensor types, circuit module (101) are adjusted by Adaptive matching and select different matching electricity Road so that Human Physiology electric signal accurately inputs high impedance signal receiving circuit module (102), and is converted into weak voltage signals V1;By weak voltage signals V1Voltage signal V is obtained by first order amplification circuit module (103) amplification2;Voltage signal V2Through Overvoltage follows circuit module (104), second level amplification and low-pass filter circuit module (105) amplification to obtain voltage signal V3; Due to high impedance signal receiving circuit module (102), first order amplification circuit module (103), second level amplification and low-pass filtering Circuit module (105) is to use anti-phase input, so amplified signal V3It needs inverter cricuit module to carry out again reverse phase to put Greatly, so that final output signal V4With the same phase of input signal, final output signal V4Meet the electricity of record test request for output Press signal;Also, output end accesses signal sampling complete circuit module and provides subsequent sampling reference voltage, guarantees that signal sampling is complete Whole property.

By the embodiment, circuit applied by high-accuracy self-adaptation physiology signal tester and test method can Accurate measurement frequency is 30Hz hereinafter, the low current signal that amplitude is 0.01nA, measurement error are within 0.50%.In addition, It is detected by human pulse signal, signal output signal-to-noise ratio is (60 ± 2) dB, and root-mean-square error is less than 5 × 10-4, signal detail Characteristic information is complete.It can be with further reference to the low-frequency weak signal test experience of embodiment 2 and the human pulse signal of embodiment 3 Test experiments result.

Embodiment 2

According to technical solution described in embodiment 1, and Fig. 1 to 4 is combined, carries out tester pilot scale study:

It is 10~400Hz that signal source inputs frequency to detector respectively, and the standard sine that amplitude is 0.55~1.18mV is believed Number.In order to measure the stability and accuracy of detector, each signal type takes the average value of 5 signals as measurement result point Analysis, pilot scale study data processed result are as shown in table 1:

Table 1

Detector pilot scale study data processed result obtains as shown in Table 1, detector amplitude error and frequency response error Within 0.5%, and being consistent property of multiple measurement results.It follows that high-accuracy self-adaptation physiology signal is tested Instrument can be stablized, accurately measure low-frequency weak signal, and technical requirement on design has been reached.

Embodiment 3

According to technical solution described in embodiment 1, and Fig. 1 to 4 is combined, carries out human pulse signal detection:

Firstly, connecting detector, signal gating switch is connected into signal path 2, and testing detector being capable of normal work Make;Secondly, pulse transducer is fixed at the radial artery of tester's arm and by sensor signal output end connecting detection instrument Input terminal;Then, (it is steady to be in tranquillization to acquisition Wave data by tester at this time after pulse signal waveform stabilization on observation oscilloscope State);Finally, being analyzed sampled data, handling to obtain the pulse signal of noiseless interference.Test tester be 23 years old and 26 years old women without medical history and male each one, the time domain and spectrum signal of experimental result are as shown in Fig. 5 to Figure 10.

Pulse experimental results shown in Fig. 5 to Figure 10: Fig. 5, Fig. 6, Fig. 7, Fig. 8 are respectively male, women tester's pulse Waveform time domain figure, wherein Fig. 5 and Fig. 7 is multicycle waveform, and Fig. 6 and Fig. 8 are waveform amplification in red frame;Fig. 9 and Figure 10 are respectively Fig. 5 is to Fig. 6, Fig. 7 to the corresponding spectrogram of Fig. 8.It can see all detailed information of pulse signal from amplified signal waveform Completely, (treated for pulse signal just for pulse signal root-mean-square error that treated (RMSE) and signal-to-noise ratio (SNR) such as table 2 Root error and signal-to-noise ratio) shown in:

Table 2

According to experimental result, when input is low frequency low current signal, according to the input of current-voltage conversion module electricity Resistance is 100M Ω, then the available detector being capable of 0.01nA grades of high-precision, stably measured low frequency low current signals.Thus It obtains, under actual measurement environment, detector can satisfy the requirement of high-acruracy survey low-frequency weak signal, and anti-interference energy Power is strong, performance is stable.

In addition, tester measurement accuracy described in the present embodiment and tester accuracy comparison in the prior art are as shown in table 3:

Table 3

As can be drawn from Table 3, the tester precision of tester compared to the prior art, the present embodiment is high.

The above is only that preferred embodiments of the present invention will be described, is limited the scope of the present invention It is fixed;The foregoing is merely a specific embodiment of the invention, are not intended to limit the scope of protection of the present invention;It is not departing from Under the premise of design spirit of the present invention, this field ordinary engineering and technical personnel any is repaired to what technical solution of the present invention was made Change, equivalent replacement, improvement etc., should fall within the scope of protection determined by the claims of the present invention.

Claims (10)

1. a kind of high-accuracy self-adaptation physiology signal tester, including shielding shell (7) and PCB circuit board (15), special Sign is:
The PCB circuit board (15) is provided with wiring region (10), BNC connector (11), signal gating switch (12) and believes Number amplification factor adjusting knob (13), the wiring region (10) include that Adaptive matching adjusts circuit module (101), high Impedance signal receiving circuit module (102), first order amplification circuit module (103), voltage follower circuit module (104), second Grade amplification and low-pass filter circuit module (105), signal inversion amplification circuit module (106), protection circuit module (107), letter Number sampling complete circuit module (108) and its circuit connection and the port signal I/O;
Four each devices in corner of the PCB circuit board (15) have a supporting screw (14) and screw ground connection;
Sensor circuit signal input end hole (1), signal testing output stomidium (2), positive electricity are laid on the shielding shell (7) Source hole (3), ground wire stomidium (4), negative supply stomidium (5), reference power source stomidium (6), signal gating switch hole (9) and signal are put Big multiple adjusting knob hole (8);
The PCB circuit board (15) is built in shielding shell (7) and is fixed on shielding shell (7) by four supporting screws (14) Bottom surface, the circuit connection of the PCB circuit board (15) and the port signal I/O and BNC connector (11), signal gating switch (12), signal amplification factor adjusting knob (13) passes through the sensor circuit signal input end hole (1) in shielding shell (7), letter Number test output terminal hole (2), positive supply stomidium (3), ground wire stomidium (4), negative supply stomidium (5), reference power source stomidium (6), letter Number gating switch hole (9), signal amplification factor adjusting knob hole (8) are drawn, and are connect with external equipment.
2. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: PCB circuit board (15), shielding shell (7), signal amplification factor adjusting knob (8), signal gating switch (9) are detachable assembly.
3. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: the external equipment Including external power supply, sensor and sensor circuit, recorder and recorder circuit.
4. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: described adaptive The both ends of auxiliary tone section circuit module (101) are separately connected sensor circuit and high impedance signal receiving circuit module (102);It is described It includes that two ALT-CH alternate channels, channel 1 and channel 2 and channel switch switch K that Adaptive matching, which adjusts circuit module (101),1、 Heat dissipating ring S1, first resistor R1, second resistance R2, 3rd resistor R3, first capacitor C1With the second capacitor C2;When sensor is active When sensor, switch K1It is switched to channel 1;When sensor is passive sensor, switch K1It is switched to channel 2.
5. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: the high impedance letter One end connection Adaptive matching of number receiving circuit module (102) adjusts circuit module (101), and the other end connects first order amplification Circuit module (103);The high impedance signal receiving circuit module (102) includes high-impedance amplifier Ug1, protection ring P, heat dissipation Ring S2, the 4th resistance R4, the 5th resistance R5With third capacitor C3;4th resistance R4For high-impedance amplifier Ug1Negative feedback resistor; 5th resistance R5One end Jie high-impedance amplifier Ug1Normal phase input end, the other end ground connection;Third capacitor C3For negative-feedback electricity Hold, with the 4th resistance R4It is in parallel;Protection ring P setting receives circuit signal input and signal output end in high impedance signal;It dissipates Hot ring S2It is arranged in Ug1Negative feedback loop on.
6. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: the first order is put One end of big circuit module (103) connects high impedance signal receiving circuit module (102), and the other end connects voltage follower circuit mould Block (104);The first order amplification circuit module (103) includes the first amplifier U1, the 6th resistance R6, the 7th resistance R7, first Potentiometer RW1, the 4th capacitor C4;6th resistance R6It connects in the first amplifier U1Inverting input terminal;7th resistance R7One end Jie One amplifier U1Normal phase input end, other end ground connection;First potentiometer RW1It connects in the first amplifier U1Two pins on adjust Save the multiple of preposition amplification, the 4th capacitor C4With the 7th resistance R7Parallel connection denoising.
7. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: the voltage follow The both ends of circuit module (104) are separately connected first order amplification circuit module (103), second level amplification and low-pass filter circuit mould Block (105);The voltage follower circuit module (104) includes the second amplifier U2The first signal path, the second amplifier U2Instead Phase input terminal is connect with output end;The signal positive input voltage of first order amplification circuit module (103) output follows circuit mould Block (104).
8. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: put the second level It is connected voltage follower circuit module (104) with one end of low-pass filter circuit module (105) greatly, other end connection signal reverse phase is put Big circuit module (106);The second level amplification and low-pass filter circuit module (105) include the second amplifier U2Second letter Number channel, the 8th resistance R8, the 9th resistance R9, the tenth resistance R10, the second potentiometer RW2, the 5th capacitor C5, the 6th capacitor C6, Seven capacitor C7;8th resistance R8, the 9th resistance R9It connects in the second amplifier U2The inverting input terminal in second signal channel;Tenth electricity Hinder R10One the second amplifier U of termination2The normal phase input end in second signal channel, other end ground connection;Second potentiometer RW2Connect second Amplifier U2The negative-feedback in second signal channel adjusts amplification factor;5th capacitor C5With the second potentiometer RW2It is in parallel;6th electricity Hold C6It connects in the second amplifier U2The output end in second signal channel and the 8th resistance R8, the 9th resistance R9Between, with the second current potential Device RW2, the 5th capacitor C5Form low-pass filter circuit;7th capacitor C7With the tenth resistance R10It is in parallel.
9. high-accuracy self-adaptation physiology signal tester as described in claim 1, it is characterised in that: the signal inversion One end connection second level amplification of amplification circuit module (106) and low-pass filter circuit module (105), other end connection protection electricity Road module (107);The signal inversion amplification circuit module (106) includes the second amplifier U2Third signal path, the tenth One resistance R11, twelfth resistor R12, thirteenth resistor R13, the 8th capacitor C8;Thirteenth resistor R13It connects in the second amplifier U2's The direction input terminal of third signal path;Twelfth resistor R12With the 8th capacitor C8It is in parallel.
10. the test side of high-accuracy self-adaptation physiology signal tester according to any one of claim 1 to 9 Method, it is characterised in that:
According to different sensor types, circuit module (101) are adjusted by Adaptive matching and select different match circuits, are made It obtains Human Physiology electric signal and accurately inputs high impedance signal receiving circuit module (102), and be converted into weak voltage signals V1
By weak voltage signals V1Voltage signal V is obtained by first order amplification circuit module (103) amplification2
Voltage signal V2By voltage follower circuit module (104), second level amplification and low-pass filter circuit module (105) amplification Obtain voltage signal V3
Due to high impedance signal receiving circuit module (102), first order amplification circuit module (103), second level amplification and low pass Filter circuit module (105) is to use anti-phase input, so amplified signal V3Inverter cricuit module is needed to carry out anti-again Mutually amplify, so that final output signal V4With the same phase of input signal, final output signal V4Meet record test request for output Voltage signal;
Also, output end accesses signal sampling complete circuit module and provides subsequent sampling reference voltage, guarantees that signal sampling is complete Property.
CN201811591619.9A 2018-09-18 2018-12-25 A kind of high-accuracy self-adaptation physiology signal tester and test method CN109620155A (en)

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