CN109602873A - It is a kind of prevent and treat fish water mo(u)ld disease Chinese herbal and crude drugs preparations and its application - Google Patents
It is a kind of prevent and treat fish water mo(u)ld disease Chinese herbal and crude drugs preparations and its application Download PDFInfo
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- CN109602873A CN109602873A CN201811648690.6A CN201811648690A CN109602873A CN 109602873 A CN109602873 A CN 109602873A CN 201811648690 A CN201811648690 A CN 201811648690A CN 109602873 A CN109602873 A CN 109602873A
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- 239000003814 drug Substances 0.000 title claims abstract description 136
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- 238000002360 preparation method Methods 0.000 title claims abstract description 125
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- 235000006226 Areca catechu Nutrition 0.000 claims description 22
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- 241000205407 Polygonum Species 0.000 claims description 22
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- 235000004347 Perilla Nutrition 0.000 claims description 21
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- 235000002428 Cinnamomum japonicum Nutrition 0.000 claims description 20
- 240000006079 Schisandra chinensis Species 0.000 claims description 19
- 235000008422 Schisandra chinensis Nutrition 0.000 claims description 19
- 244000302909 Piper aduncum Species 0.000 claims description 16
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- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 13
- 239000011425 bamboo Substances 0.000 claims description 13
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- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 4
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- 238000001514 detection method Methods 0.000 description 2
- QDOXWKRWXJOMAK-UHFFFAOYSA-N dichromium trioxide Chemical compound O=[Cr]O[Cr]=O QDOXWKRWXJOMAK-UHFFFAOYSA-N 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
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- 239000001301 oxygen Substances 0.000 description 2
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- 150000003242 quaternary ammonium salts Chemical class 0.000 description 2
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Classifications
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Abstract
The invention discloses a kind of Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease and its applications, belong to the field that water mo(u)ld disease prevents and treats in aquaculture, and the present invention can prevent and treat fish water mo(u)ld disease, have no effect to healthy fish and water quality；Microscopy finds do not occur water mo(u)ld infection to the inhibiting rate height of mucor, the water mo(u)ld of fish etc., can effectively control the generation of fish water mo(u)ld disease and its complication, effectively cure fish water mo(u)ld disease；Water quality can be improved, water body environment does not destroy microecological balance in water body without influence；Chinese herbal medicine noresidue in culture environment of aquatic products, high-efficiency low-toxicity, and have no toxic side effect to fish etc..
Description
Technical field
The invention belongs to the technical field that water mo(u)ld disease in aquaculture prevents and treats, in particular to a kind of prevention and treatment fish water mo(u)lds
The Chinese herbal and crude drugs preparations of disease and its application.
Background technique
The scale of aquaculture is constantly expanded in recent years, but brings other problems at the same time.One of the most common is
The generation of water mo(u)ld has caused mycosis, especially water body environment deteriorate or contaminated, mechanical damage, transport, association compel stress wait
Under the influence of factor, fish disease incidence reaches 100%, and the death rate is high.This environment is coped with, the research and development of aquaculture drug are opposite
Lag, and will appear that disease is multiple, germ drug resistance is more and more serious, or even available without medicine, it not can control the feelings such as disease
Condition.
At present the common control method of water mo(u)ld disease be using chemical agent, using malachite green, formalin (formaldehyde),
The substances such as quaternary ammonium salt, many of drug because of high residue, high pollution, to environmental nuisance and drug resistance the reason of, and gradually by
It eliminates.
Malachite green and its metabolite have a variety of poison such as high toxicity, high residue, high carcinogenic and high teratogenesis, mutagenesis secondary
Effect；Formalin (formaldehyde), it is volatile, there are the toxic side effects such as intense irritation, corrosivity and easy residual, has directly to human body
Harm；Quaternary ammonium salt, the effect for pressing down killing fungus is more poor than malachite green, formalin (formaldehyde), and antimicrobial spectrum is narrow, while can
To cause fish anoxic；The above substance is very harmful to fish and breeding environment, so not being prevention and treatment fish water mo(u)ld disease
Be preferably selected.Therefore, it is badly in need of deeply developing environmentally friendly, pollution-free, nuisanceless and low-residual the preparation of one kind to meet
The urgent need of culture fishery.
Summary of the invention
The primary purpose of the present invention is that providing a kind of Chinese herbal and crude drugs preparations that can prevent and treat fish water mo(u)ld disease.
Another object of the present invention is to provide the preparation methods of said herbal medicine preparation.
A further object of the present invention is to provide the applications of said herbal medicine preparation.
The technical solution used in the present invention is:
A kind of Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease, are made: purple perilla 2~18 of the ingredient of following parts by weight
Part, 3~10 parts of frutus cnidii, 3~10 parts of the tuber of stemona, 3~10 parts of Chinese wild pepper, 4~13 parts of betel nut, 5~13 parts of polygonum cuspidate, cinnamomum japonicum
6~15 parts, 3~11 parts of Herba Epimedii, 6~15 parts of desmodium triquetrum, 4~11 parts of big maple, 3~10 parts of semen momordicae, the five tastes
2~9 parts of son, 3~12 parts of semen brassicae, 5~16 parts of white flower lantern, 5~13 parts of selaginella doederlleini and 4~16 parts of Lantana camara.
Further, it is made of the ingredient of following parts by weight: 3~16 parts of purple perilla, 3~8 parts of frutus cnidii, the tuber of stemona 3~8
Part, 3~8 parts of Chinese wild pepper, 5~11 parts of betel nut, 5~11 parts of polygonum cuspidate, 5~11 parts of cinnamomum japonicum, 4~9 parts of Herba Epimedii, desmodium triquetrum 6~
12 parts, 4~9 parts of big maple, 2~8 parts of semen momordicae, 2~8 parts of Schisandra chinensis, 4~10 parts of semen brassicae, 6~12 parts of white flower lantern, stone
5~11 parts and 6~12 parts of Lantana camara of upper cypress.
Further, it is made of the ingredient of following parts by weight: 3~10 parts of purple perilla, 3~5 parts of frutus cnidii, the tuber of stemona 3~5
Part, 3~5 parts of Chinese wild pepper, 5~6 parts of betel nut, 5~8 parts of polygonum cuspidate, 5~8 parts of cinnamomum japonicum, 4~7 parts of Herba Epimedii, desmodium triquetrum
6~8 parts, 4~6 parts of big maple, 2~6 parts of semen momordicae, 2~6 parts of Schisandra chinensis, 4~7 parts of semen brassicae, white flower lantern
6~8 parts, 5~8 parts of selaginella doederlleini and 6~8 parts of Lantana camara.
It further, further include 2~8 parts of Chinese gall, 4~9 parts of kuh-seng and 5~11 parts of kidney channel grass.
The preparation method of Chinese herbal and crude drugs preparations described above, comprising the following steps:
(1) by described in any of the above-described formula weigh purple perilla, frutus cnidii, the tuber of stemona, Chinese wild pepper, betel nut, polygonum cuspidate, cinnamomum japonicum,
Herba Epimedii, desmodium triquetrum, big maple, semen momordicae, Schisandra chinensis, semen brassicae, white flower lantern, selaginella doederlleini, Lantana camara or/and Chinese gall
Or/and kuh-seng or/and kidney channel grass, pulverize and sieve；
(2) 50~100 parts of water are added, boil, keep the temperature 1~2h, it is cooling up to Chinese herbal and crude drugs preparations.
Further, sieve described in step (1) is 120 mesh~250 mesh.
Application of the said herbal medicine preparation in prevention and treatment fish water mo(u)ld disease.
Application of the said herbal medicine preparation in preparation treatment fish water mo(u)ld disease reagent.
Further, the water mo(u)ld disease is mucormycosis, saprolegniasis, branchiomycosis.
Further, the fish are freshwater fish, seawater fish；The freshwater fish be soft-shelled turtle, Chelonian, mandarin fish,
The giant salamander, Tilapia mossambica, mandarin fish, bamboo shoot shell fish at least one；The seawater fish is thorn tail fish, butterfly fish, damselfish, lid thorn
At least one of fish, Moorish idol.
The beneficial effects of the present invention are:
The present invention can prevent and treat fish water mo(u)ld disease, have no effect to healthy fish and water quality；Microscopy is found to fish
The suppression of mucor, water mo(u)ld etc. kill rate height, can effectively control the generation of fish water mo(u)ld disease and its complication, effectively cure
Fish water mo(u)ld disease；Water quality can be improved, water pH value, dissolved oxygen, ammonia-nitrogen content are unchanged；It is bacillus subtilis in water body, beneficial
The number of viable such as algae do not destroy microecological balance in water body without significant change；The Chinese herbal and crude drugs preparations are in culture environment of aquatic products
Noresidue, high-efficiency low-toxicity, and have no toxic side effect to fish.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Embodiment 1
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 3g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
5g, betel nut 5g, polygonum cuspidate 5g, cinnamomum japonicum 8g, Herba Epimedii 4g, desmodium triquetrum 6g, big maple 48g, semen momordicae 2g, Schisandra chinensis 2g, sinapsis alba
Sub- 4g, white flower lantern 6g, selaginella doederlleini 5g, Lantana camara 6g.
Usage one: said herbal medicine drug being crushed respectively after 120 mesh pulvis are made, and is mixed and made into prevention and treatment fish water mo(u)ld
The Chinese herbal and crude drugs preparations of disease；Said herbal medicine preparation is added into 100 parts of water (weight ratio), is boiled, 40 DEG C of heat preservations are kept for 1 hour, cooling
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine preparation being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Direct full pool spilling head uses or Chinese herbal and crude drugs preparations and water are by 1:50 (weight ratio) plus 40 DEG C of hot water, and 40
It DEG C impregnates 2 hours, (dosage is that every 667 cubic meter of water is splashed the present embodiment 500g Chinese herbal medicine system for full pool spilling head after cooling to room temperature
Agent).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, can effectively inhibit the Mucor of 90% or more soft-shelled turtle
The generation of disease, saprolegniasis, branchiomycosis.
Embodiment 2
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 16g, frutus cnidii 8g, tuber of stemona 8g, the leaf of bamboo
Green pepper 8g, betel nut 11g, polygonum cuspidate 11g, cinnamomum japonicum 11g, Herba Epimedii 9g, desmodium triquetrum 12g, big maple 9g, semen momordicae 8g, Schisandra chinensis 8g,
Semen brassicae 10g, white flower lantern 12g, selaginella doederlleini 11g, Lantana camara 12g.
Usage one: said herbal medicine component being crushed respectively after the pulvis of 300 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 100 DEG C of heat preservations are kept for 1 hour, cold for Chinese herbal and crude drugs preparations and water
But it splashes, impregnate afterwards, or packing is spare.
Usage two: said herbal medicine group being crushed respectively after the pulvis of 300 mesh is made, and is mixed and made into prevention and treatment fish water mo(u)ld
The Chinese herbal and crude drugs preparations of disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water and add 100 DEG C of hot water by 1:50 (weight ratio),
100 DEG C are impregnated 1 hour, and (dosage is that every 667 cubic meter of water uses the present embodiment 500g medium-height grass to full pool spilling head after cooling to room temperature
Medicine).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of 90% or more tortoise, water
The generation of mildew, branchiomycosis.
Embodiment 3
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 2g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
5g, betel nut 4g, polygonum cuspidate 5g, cinnamomum japonicum 6g, Herba Epimedii 3g, desmodium triquetrum 6g, big maple 4g, semen momordicae 3g, Schisandra chinensis 2g, semen brassicae
3g, white flower lantern 5g, selaginella doederlleini 5g, Lantana camara 4g.
Usage one: said herbal medicine ingredient being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；1 part of Chinese herbal and crude drugs preparations adds 100 parts of water (weight ratio), boils, and 40 DEG C of heat preservations are kept for 1 hour, after cooling
It splashes, impregnate, or packing is spare.
Usage two: said herbal medicine ingredient being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Direct full pool spilling head uses or Chinese herbal and crude drugs preparations and water are by 1:50 (weight ratio) plus 40 DEG C of hot water, and 40
It DEG C impregnates 2 hours, full pool spilling head after cooling to room temperature (dosage be every cubic meter of water splash the present embodiment 500g Chinese herbal medicine).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit 90% or more butterfly fish mucormycosis,
The generation of saprolegniasis, branchiomycosis.
Embodiment 4
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 18g, frutus cnidii 10g, tuber of stemona 10g, bamboo
Leaf green pepper 10g, betel nut 13g, polygonum cuspidate 13g, cinnamomum japonicum 15g, Herba Epimedii 11g, desmodium triquetrum 15g, big maple 11g, semen momordicae 10g, five
Taste 9g, semen brassicae 12g, white flower lantern 16g, selaginella doederlleini 13g, Lantana camara 16g.
Usage one: said herbal medicine ingredient being crushed respectively after the pulvis of 250 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；1 part of Chinese herbal and crude drugs preparations adds 100 parts of water (weight ratio), boils, and 100 DEG C of heat preservations are kept for 1 hour, cooling
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine ingredient being crushed respectively after the pulvis of 300 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Direct full pool spilling head use or Chinese herbal and crude drugs preparations and water press 1:50 (weight ratio) plus 100 DEG C of hot water,
40 DEG C are impregnated 2 hours, full pool spilling head after cooling to room temperature (dosage be every cubic meter of water splash the present embodiment 500g Chinese herbal medicine).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of damselfish 87%, water mold
The generation of disease, branchiomycosis.
Embodiment 5
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 8g, frutus cnidii 5g, tuber of stemona 5g, Chinese wild pepper
5g, betel nut 6g, polygonum cuspidate 8g, cinnamomum japonicum 18g, Herba Epimedii 7g, desmodium triquetrum 8g, big maple 6g, semen momordicae 6g, Schisandra chinensis 6g, sinapsis alba
Sub- 7g, white flower lantern 8g, selaginella doederlleini 8g, Lantana camara 8g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 40 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water and add 40 DEG C of hot water by 1:50 (weight ratio),
40 DEG C are impregnated 1 hour, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit 90% or more indianfish Mucor
The generation of disease, saprolegniasis, branchiomycosis.
Embodiment 6
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 3g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
3g, betel nut 5g, polygonum cuspidate 5g, cinnamomum japonicum 5g, Herba Epimedii 4g, desmodium triquetrum 6g, big maple 4g, semen momordicae 2g, Schisandra chinensis 2g, semen brassicae
4g, white flower lantern 6g, selaginella doederlleini 5g, Lantana camara 6g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 80 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal medicine of bacterium disease；Directly make full pool spilling head use or Chinese herbal medicine and water by 1:50 (weight ratio) plus 80 DEG C of hot water, 80 DEG C of immersions
1 hour, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of Moorish idol 90%, water mold
The generation of disease, branchiomycosis.
Embodiment 7
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 2g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
5g, betel nut 4g, polygonum cuspidate 5g, cinnamomum japonicum 6g, Herba Epimedii 3g, desmodium triquetrum 6g, big maple 4g, semen momordicae 3g, Schisandra chinensis 2g, semen brassicae
3g, white flower lantern 5g, selaginella doederlleini 5g, Lantana camara 4g, 5 parts of 2 parts of Chinese gall, 4 parts of kuh-seng and kidney channel grass.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；1 part of Chinese herbal and crude drugs preparations adds 100 parts of water (weight ratio), boils, and 40 DEG C of heat preservations are kept for 1 hour, after cooling
It splashes, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal medicine of bacterium disease；By 1:50 (weight ratio) plus 40 DEG C of hot water, 40 DEG C are impregnated 2 for direct full pool spilling head use or Chinese herbal medicine and water
Hour, full pool spilling head after cooling to room temperature (dosage be every cubic meter of water splash the present embodiment 500g Chinese herbal medicine).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of bamboo shoot shell fish 93%, water
The generation of mildew, branchiomycosis.
Embodiment 8
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 18g, frutus cnidii 10g, tuber of stemona 10g, bamboo
Leaf green pepper 10g, betel nut 13g, polygonum cuspidate 13g, cinnamomum japonicum 15g, Herba Epimedii 11g, desmodium triquetrum 15g, big maple 11g, semen momordicae 10g, five
Taste 9g, semen brassicae 12g, white flower lantern 16g, selaginella doederlleini 13g, Lantana camara 16g, 8 parts of Chinese gall, 9 parts of kuh-seng and kidney channel grass 11
Part.
Usage one: said herbal medicine ingredient being crushed respectively after the pulvis of 250 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；1 part of Chinese herbal and crude drugs preparations adds 100 parts of water (weight ratio), boils, and 80 DEG C of heat preservations are kept for 1 hour, after cooling
It splashes, impregnate, or packing is spare.
Usage two: said herbal medicine ingredient being crushed respectively after the pulvis of 300 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Direct full pool spilling head uses or Chinese herbal and crude drugs preparations and water are by 1:50 (weight ratio) plus 80 DEG C of hot water, and 80
It DEG C impregnates 2 hours, full pool spilling head after cooling to room temperature (dosage be every cubic meter of water splash the present embodiment 500g Chinese herbal medicine).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of Tilapia mossambica 84%, water
The generation of mildew, branchiomycosis.
Embodiment 9
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 3g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
5g, betel nut 5g, polygonum cuspidate 5g, cinnamomum japonicum 8g, Herba Epimedii 4g, desmodium triquetrum 6g, big maple 48g, semen momordicae 2g, Schisandra chinensis 2g, sinapsis alba
Sub- 4g, white flower lantern 6g, selaginella doederlleini 5g, Lantana camara 6g, Chinese gall 2g, kuh-seng 4g, kidney channel grass 5g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal medicine of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 40 DEG C of heat preservations are kept for 1 hour for Chinese herbal medicine and water, splash after cooling,
It impregnates, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal medicine of bacterium disease；Directly make full pool spilling head use or Chinese herbal medicine and water by 1:50 (weight ratio) plus 40 DEG C of hot water, 40 DEG C of immersions
It impregnates 1 hour within 2 hours or 100 DEG C, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of Tilapia mossambica 87%, water
The generation of mildew, branchiomycosis.
Embodiment 10
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 16g, frutus cnidii 8g, tuber of stemona 8g, the leaf of bamboo
Green pepper 8g, betel nut 11g, polygonum cuspidate 11g, cinnamomum japonicum 11g, Herba Epimedii 9g, desmodium triquetrum 12g, big maple 9g, semen momordicae 8g, Schisandra chinensis 8g,
Semen brassicae 10g, white flower lantern 12g, selaginella doederlleini 11g, Lantana camara 12g, Chinese gall 8g, kuh-seng 9g, kidney channel grass 11g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 250 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 80 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug is crushed after the pulvis of 300 mesh is made respectively according to a conventional method, is mixed anti-
Control the Chinese herbal and crude drugs preparations of fish water mo(u)ld disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water by 1:50 (weight ratio)
Add 80 DEG C to impregnate 2 hours, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 200g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of Tilapia mossambica 88%, water
The generation of mildew, branchiomycosis.
Embodiment 11
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 16g, frutus cnidii 5g, tuber of stemona 5g, the leaf of bamboo
It is green pepper 8g, betel nut 8g, polygonum cuspidate 8g, cinnamomum japonicum 11g, Herba Epimedii 7g, desmodium triquetrum 10g, big maple 8g, semen momordicae 6g, Schisandra chinensis 5g, white
Mustard seed 8g, white flower lantern 10g, selaginella doederlleini 9g, Lantana camara 10g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 180 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 70 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water and add 70 DEG C of hot water by 1:50 (weight ratio),
70 DEG C are impregnated 1.5 hours, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of mandarin fish 88%, water mold
The generation of disease, branchiomycosis.
Embodiment 12
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 16g, frutus cnidii 8g, tuber of stemona 8g, the leaf of bamboo
Green pepper 8g, betel nut 11g, polygonum cuspidate 11g, cinnamomum japonicum 11g, Herba Epimedii 9g, desmodium triquetrum 12g, big maple 9g, semen momordicae 8g, Schisandra chinensis 8g,
Semen brassicae 10g, white flower lantern 12g, selaginella doederlleini 11g, Lantana camara 12g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 120 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 60 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 200 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water and add 60 DEG C of hot water by 1:50 (weight ratio),
60 DEG C are impregnated 1 hour, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of the giant salamander 88%, water
The generation of mildew, branchiomycosis.
Embodiment 13
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 3g, frutus cnidii 3g, tuber of stemona 3g, Chinese wild pepper
3g, betel nut 5g, polygonum cuspidate 5g, cinnamomum japonicum 5g, Herba Epimedii 4g, desmodium triquetrum 6g, big maple 4g, semen momordicae 2g, Schisandra chinensis 2g, semen brassicae
4g, white flower lantern 6g, selaginella doederlleini 5g, Lantana camara 6g, Chinese gall 2g, kuh-seng 4g and kidney channel grass 5g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 250 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；By 1:100 (weight ratio) plus boiling boiling, 90 DEG C of heat preservations are kept for 1 hour, cooling for Chinese herbal and crude drugs preparations and water
After splash, impregnate, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 300 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water and add 90 DEG C of hot water by 1:50 (weight ratio),
90 DEG C are impregnated 1 hour, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the thorn mucormycosis of tail fish 88%, water
The generation of mildew, branchiomycosis.
Embodiment 14
The Chinese herbal and crude drugs preparations of fish water mo(u)ld disease are prevented and treated, each component is as follows: purple perilla 8g, frutus cnidii 5g, tuber of stemona 5g, Chinese wild pepper
3g, betel nut 8g, polygonum cuspidate 8g, cinnamomum japonicum 5g, Herba Epimedii 7g, desmodium triquetrum 10g, big maple 8g, semen momordicae 6g, Schisandra chinensis 5g, sinapsis alba
Sub- 8g, white flower lantern 10g, selaginella doederlleini 9g, Lantana camara 10g, Chinese gall 4g, kuh-seng 6g, kidney channel grass 8g.
Usage one: said herbal medicine drug being crushed respectively after the pulvis of 250 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Chinese herbal and crude drugs preparations and water are by 1:100 (weight ratio) plus boiling boiling, and 80 DEG C of heat preservations are kept for 1 hour, waste
It splashes, impregnate after cooling, or packing is spare.
Usage two: said herbal medicine drug being crushed respectively after the pulvis of 280 mesh is made, and is mixed and made into prevention and treatment fish water mold
The Chinese herbal and crude drugs preparations of bacterium disease；Directly make full pool spilling head use or Chinese herbal and crude drugs preparations and water by 1:50 (weight ratio) plus 80 DEG C of hot water
It impregnates 2 hours, full pool spilling head after cooling to room temperature (dosage is every 667 cubic meter of water Chinese herbal medicine 500g).
Test statistics the result shows that, after Chinese herbal and crude drugs preparations of the present invention, effectively inhibit the mucormycosis of bamboo shoot shell fish 88%, water
The generation of mildew, branchiomycosis.
The Chinese herbal and crude drugs preparations being prepared using above-described embodiment carry out the experiment of prevention and treatment fish water mo(u)ld disease.
Fish water mo(u)ld disease tests (one)
The disease-free Tilapia mossambica of selection health, mandarin fish, bamboo shoot shell fish are grouped first, take Chinese medicine preparation (embodiment 1)
It is divided into middle dose group and high dose group, is added 40 DEG C of hot water, the weight ratio of Chinese herbal and crude drugs preparations and water is 1:50, is uniformly mixed, 40
DEG C heat preservation 2h, cool to room temperature, obtain Chinese herbal and crude drugs preparations solution.Chinese herbal and crude drugs preparations solution and water are diluted according to special ratios again
Afterwards, it is divided into middle dose group, high dose group progress full pool spilling head, once a day, once every three days.Tilapia mossambica dedicated feed, osmanthus
Flower fish is fed using the small anchovies of health, and bamboo shoot shell fish uses dedicated fish meal.
The fish health status that each aquaculture pond in medication front and back is detected by microscopy, the results are shown in Table 1.
1 No. 1 aquaculture ponds of table use the fish health status of each aquaculture pond before and after Chinese herbal and crude drugs preparations of the present invention
As shown in Table 1, after using Chinese herbal and crude drugs preparations of the present invention, on the healthy item number of Tilapia mossambica, mandarin fish and bamboo shoot shell fish
It rises, the decline of water mo(u)ld disease item number.Relative to blank control group, the Chinese herbal and crude drugs preparations that the present invention uses have obviously water mo(u)ld disease
Inhibiting effect, the inhibiting rate of middle dosage medication group is 91.1%, and the inhibiting rate of high dose is 92.2%, significantly larger than control group
2.2%.
Fish water mo(u)ld disease tests (two)
Aquaculture pond is carried out disinfection sterilization, after one month, is filled the water toward each aquaculture pond, 1.8 meters of the depth of water, the water quality of aquaculture pond
Meet country " water quality standard for fishery " GB11607-1998 requirement.
Experimental group: each aquaculture pond is placed with the Chinese herbal and crude drugs preparations of the embodiment of respective number, and each pond, which is put in a suitable place to breed, suffers from water mold
Fish 9 of the fish 21 of bacterium disease and health, totally 30, each pond.The Chinese herbal and crude drugs preparations of embodiment 2~9 are used by microscopy detection
The fish health status of each aquaculture pond in front and back, statistical result are shown in Table 2.
Table 2 uses the fish health status of each aquaculture pond before and after Chinese herbal and crude drugs preparations of the invention
As shown in Table 2, after having used Chinese herbal and crude drugs preparations of the invention, the item number of healthy fish is to rise, and obtains water mo(u)ld
The item number of sick fish has dropped, and illustrates that Chinese herbal and crude drugs preparations prepared by the present invention have an inhibition to water mo(u)ld disease, inhibiting rate reach 80% with
On, up to 93.3%；And Chinese herbal and crude drugs preparations prepared by the present invention can treat water mo(u)ld disease.As it can be seen that medium-height grass of the invention
Medicine preparation is to the cure rate of water mo(u)ld disease up to 90% or more.
Influence experiment of the Chinese herbal and crude drugs preparations to water quality
The fish pond of Guangzhou aquaculture base, Chinese herbal and crude drugs preparations prepared by the present invention of splashing are chosen, dosage is every 667 vertical
Fang meter Shui splashes 500g Chinese herbal and crude drugs preparations solution, waits the detection for carrying out water quality after a week, to bacillus subtilis therein, beneficial
The number of viable such as algae are detected.
After having used Chinese herbal and crude drugs preparations of the invention, discovery water pH value, dissolved oxygen, ammonia-nitrogen content are without significant changes, explanation
Chinese herbal medicine is unchanged using rear water quality；The number of viable such as bacillus subtilis, beneficial algae are monitored in water body without significant change, so
Say that it does not destroy microecological balance in water body.
Said effect test discovery, Chinese herbal medicine of the invention can effectively inhibit or kill Mucor, water mold, branchiomycosis.
Chinese herbal medicine of the invention passes through plant-derived a variety of alkenes, aldehydes volatile oil and the organic acid etc. being wherein rich in, and plays suppression and kills Mucor
Bacterium, water mo(u)ld etc., drug effect is certain, to the cure rate of water mo(u)ld disease up to 90% or more.According to different water environments, usage amount
Are as follows: water body 200~500g of this Chinese herbal medicine per acre reaches 90% or more to the inhibiting effect of water mo(u)ld.Chinese herbal medicine of the invention
Preparation directly splashes into pond using simplicity；Or full pool spilling head, immersion after 40 DEG C~100 DEG C holdings cooling in 0.5~1 hour；
Or packing is spare, for treating mucormycosis, saprolegniasis, branchiomycosis.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. a kind of Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease, which is characterized in that be made of the ingredient of following parts by weight: purple
Soviet Union 2~18 parts, 3~10 parts of frutus cnidii, 3~10 parts of the tuber of stemona, 3~10 parts of Chinese wild pepper, 4~13 parts of betel nut, polygonum cuspidate 5~13 part, day
6~15 parts of Zhu Gui, 3~11 parts of Herba Epimedii, 6~15 parts of desmodium triquetrum, 4~11 parts of big maple, 3~10 parts of semen momordicae, Schisandra chinensis 2~
9 parts, 3~12 parts of semen brassicae, 5~16 parts of white flower lantern, 5~13 parts of selaginella doederlleini and 4~16 parts of Lantana camara.
2. a kind of Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease according to claim 1, which is characterized in that by following heavy
The ingredient of amount number is made: 3~16 parts of purple perilla, 3~8 parts of frutus cnidii, 3~8 parts of the tuber of stemona, 3~8 parts of Chinese wild pepper, betel nut 5~11
Part, 5~11 parts of polygonum cuspidate, 5~11 parts of cinnamomum japonicum, 4~9 parts of Herba Epimedii, 6~12 parts of desmodium triquetrum, 4~9 parts of big maple, semen momordicae 2
~8 parts, 2~8 parts of Schisandra chinensis, 4~10 parts of semen brassicae, 6~12 parts of white flower lantern, 5~11 parts of selaginella doederlleini and Lantana camara 6~12
Part.
3. a kind of Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease according to claim 1, which is characterized in that by following heavy
Amount number ingredient be made: 3~8 parts of purple perilla, 3~5 parts of frutus cnidii, 3~5 parts of the tuber of stemona, 3~5 parts of Chinese wild pepper, 5~6 parts of betel nut,
5~8 parts of polygonum cuspidate, 5~8 parts of cinnamomum japonicum, 4~7 parts of Herba Epimedii, 6~8 parts of desmodium triquetrum, 4~6 parts of big maple, 2~6 parts of semen momordicae,
2~6 parts of Schisandra chinensis, 4~7 parts of semen brassicae, 6~8 parts of white flower lantern, 5~8 parts of selaginella doederlleini and 6~8 parts of Lantana camara.
4. a kind of described in any item Chinese herbal and crude drugs preparations for preventing and treating fish water mo(u)ld disease, feature exist according to claim 1~3
In further including 2~8 parts of Chinese gall, 4~9 parts of kuh-seng and 5~11 parts of kidney channel grass.
5. the preparation method of the described in any item Chinese herbal and crude drugs preparations of Claims 1 to 4, which comprises the following steps:
(1) purple perilla, frutus cnidii, the tuber of stemona, Chinese wild pepper, betel nut, polygonum cuspidate, India are weighed by any one of Claims 1 to 4 formula
Osmanthus, Herba Epimedii, desmodium triquetrum, big maple, semen momordicae, Schisandra chinensis, semen brassicae, white flower lantern, selaginella doederlleini, Lantana camara or/and five times
Son or/and kuh-seng or/and kidney channel grass, pulverize and sieve；
(2) 50~100 parts of water are added, are boiled, 1~2h is kept the temperature, it is cooling up to Chinese herbal and crude drugs preparations.
6. preparation method according to claim 5, which is characterized in that sieve described in step (1) is 120 mesh~250 mesh.
7. application of the described in any item Chinese herbal and crude drugs preparations of Claims 1 to 4 in prevention and treatment fish water mo(u)ld disease.
8. application of the described in any item Chinese herbal and crude drugs preparations of Claims 1 to 4 in preparation treatment fish water mo(u)ld disease reagent.
9. application according to claim 7 or 8, which is characterized in that the water mo(u)ld disease is mucormycosis, saprolegniasis, the gill
Mildew.
10. application according to claim 7 or 8, which is characterized in that the fish are freshwater fish, seawater fish；Institute
The freshwater fish stated is at least one of soft-shelled turtle, Chelonian, mandarin fish, the giant salamander, Tilapia mossambica, mandarin fish, bamboo shoot shell fish；The fish
Class is to pierce at least one of tail fish, butterfly fish, damselfish, indianfish, Moorish idol.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011547A (en) * | 2007-01-30 | 2007-08-08 | 广东省农业科学院兽医研究所 | Chinese herbal medicine preparation for preventing and treating aquatic product animal mycoses, its preparation process and use |
| US20070237837A1 (en) * | 2002-09-04 | 2007-10-11 | Biomor Israel Ltd. | Biocompatible tea tree oil compositions |
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2018
- 2018-12-30 CN CN201811648690.6A patent/CN109602873A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070237837A1 (en) * | 2002-09-04 | 2007-10-11 | Biomor Israel Ltd. | Biocompatible tea tree oil compositions |
| CN101011547A (en) * | 2007-01-30 | 2007-08-08 | 广东省农业科学院兽医研究所 | Chinese herbal medicine preparation for preventing and treating aquatic product animal mycoses, its preparation process and use |
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Application publication date: 20190412 |