CN1094608A - container for medical use - Google Patents

container for medical use Download PDF

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Publication number
CN1094608A
CN1094608A CN 93120852 CN93120852A CN1094608A CN 1094608 A CN1094608 A CN 1094608A CN 93120852 CN93120852 CN 93120852 CN 93120852 A CN93120852 A CN 93120852A CN 1094608 A CN1094608 A CN 1094608A
Authority
CN
China
Prior art keywords
mentioned
pharmaceutical vial
box
container
medical use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 93120852
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Chinese (zh)
Inventor
梅北耕司
田口哲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roussel Morishita Co Ltd
Original Assignee
Roussel Morishita Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2924593U external-priority patent/JPH0686738U/en
Application filed by Roussel Morishita Co Ltd filed Critical Roussel Morishita Co Ltd
Publication of CN1094608A publication Critical patent/CN1094608A/en
Pending legal-status Critical Current

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Abstract

Container for medical use of the present invention is by the solution container 1 of 4 sealings in coupling part and has box 3 bottom tube-like and that circulation of air hole 8 is arranged to couple together, the oral area of pharmaceutical vial 2 down the tubular pharmaceutical vial fixed mount 13 of plug-in mounting can be inserted in the box 3 movably, between the fixed mount 13 of pharmaceutical vial and box 3 bottoms, form confined space, be maintained under the state of sealing system, can promptly be communicated with pharmaceutical vial 2 and solution container 1 with double needle 16, when treating, drop can promptly carry out aseptic medicament dissolving operation, and the keeping space is dwindled, number of components is reduced, total length is shortened.

Description

Container for medical use
The present invention relates to a kind of container for medical use, it in the container of sealing system, being dissolved in the solution such as normal saline and D/W such as powder medicine and the such solid, shaped medicament of freeze-dried medicament, makes injection and can carry out drop in use.
Some antibiotics and Blood Preparations from the stability problem of galenic pharmacy, are to make to offer behind the solid preparation medically, make its dissolving earlier before use and make injection after vein carries out administration.At this moment the dissolving operation of medicament, former all to be the hollow double needle that blade tip arranged with two ends the pharmaceutical vial of each personal rubber stopper seal and solution container be interconnected carries out.If such connection operates in and carries out medicament under the state that the rubber stopper of two containers and the double needle of hollow etc. are touched by ambient atmos contaminated danger is just arranged.
Therefore, the scheme of the container for medical use of the various connections operations that can carry out pharmaceutical vial and solution container in sealing system is proposed.In the clear 61-501129 communique of the special table of Japan Patent a kind of medical container is disclosed for example, in this container, sealed container and flexible solution container that pharmaceutical vial is housed are coupled together with pipe guide, and in this pipe guide, communication apparatus is being set, in addition, disclose again in the Japanese patent laid-open 2-1277 communique a kind of can be simply after means of communication is improved and be communicated with the container for medical use of operation reliably.
Above-mentioned spy shows in the clear 61-501129 communique disclosed container for medical use to be had and will spend many time and be communicated with operational problem.
Above-mentioned spy opens in the flat 2-1277 communique disclosed container for medical use and has done many about being communicated with the significant improvement of simple to operateization, but it must just can be communicated with by the rotating operation of bottle cap, and therefore it's hard to say, and it has and the essential on-the-spot corresponding simplicity of the emergency medical service of injection medicament rapidly.In addition, because the total length of above-mentioned container for medical use is longer, the number of components that constitutes container is also more, therefore difficultly is applicable to the situation that the medicament site of storage is narrow, and must spend more funds and abandon the medical instruments that these uses are over.
On the other hand, long as container for medical use, container for medical use and the pressure head that carries out between the drop position will reduce, will reduce to intravenous injection pressure, under opposite extreme situations, for example blood can flow backwards from pricking at intravenous entry needle, thereby can not carry out drop.Therefore, in order not bring obstacle, must shorten the total length of container for medical use as much as possible to falling the drop that carries out naturally.
The present invention provides a kind of like this container for medical use in order to address the above problem, it can promptly make pharmaceutical vial and solution container be communicated with being maintained under the state of sealing system, when treating, drop can promptly carry out aseptic medicament dissolving operation, and the keeping space is dwindled, number of components reduces and total length shortens.
In order to achieve the above object, container for medical use of the present invention is made into such structure.Be that it has the connector sealed solution container partly that thin film is sealed; The bottom tube-like box is arranged, and its bottom has the plug that is made of elastomeric material to seal, and in the bottom connection tube that connects in the above-mentioned connector part by being fitted to is arranged, simultaneously the tube portion of this box through hole that has aerofluxus to use; The fixed mount that has flange, and at least one air flow through hole is being set on flange portion, the recess in the bottom is being provided with opening portion simultaneously, and this can be maintained in the above-mentioned box vertically movably; Pharmaceutical vial, it can be in the said fixing anchor clamps be maintained at above-mentioned box movably under the oral area that the plug that is made of elastomeric material is sealed is embedded into state in the above-mentioned recess; The hollow double needle, it can be maintained in the confined space that forms between the oral area of pharmaceutical vial and the above-mentioned tubular box bottom vertically movably, and make can transfixation above-mentioned box, each plug of pharmaceutical vial and above-mentioned thin film, and this double needle also has a wheel hub, be normal value in order to keep the transfixation degree of depth; First shield, following above-mentioned through hole of its state before with respect to box pharmaceutical vial being pressed into are closed and are kept the airtight conditions of above-mentioned confined space, and when with respect to box pharmaceutical vial being pressed into, it breaks away from above-mentioned through hole; The secondary shielding body, with above-mentioned first shield above-mentioned confined space is maintained airtight conditions under its state before pharmaceutical vial being pressed into, above-mentioned through hole is closed during each plug of above-mentioned box, pharmaceutical vial and above-mentioned thin film transfixation certain depth and above-mentioned confined space is maintained airtight conditions at double needle with respect to above-mentioned box.
Because the present invention possesses solution container, have bottom tube-like box, make the fixed mount of the pharmaceutical vial of the tubular that the oral area of pharmaceutical vial its plug-in mounting down, be provided with in the centre hollow of wheel hub double needle, be arranged on the through hole on the box and be arranged on the shield that can break away from of through hole, therefore with the simple operations of pushing pharmaceutical vial pharmaceutical vial and solution container sterilely are communicated with rapidly, and can promptly carry out the dissolving operation of medicament.
And, owing to use container for medical use of the present invention, be pharmaceutical vial to be remained under the state that is pressed in the box when dissolved medicament is carried out drop, so can be the shortening of the total length of container, can fully increase container for medical use and carry out drop between the drop position.
In addition, can make number of components reduce, container dimensional is dwindled according to the container for medical use relevant with the present invention, therefore garbage, the especially container for medical use of the 3rd, the 4th embodiment that can reduce after finishing using can be handled garbage more simply respectively.
Fig. 1 is the axonometric chart of the container for medical use of the first embodiment of the present invention,
Fig. 2 is the exploded perspective view of container for medical use shown in Figure 1,
Fig. 3 is the skiagraph of the fixed mount of the pharmaceutical vial in the container for medical use shown in Figure 1,
Fig. 4 is the skiagraph of the double needle in the container for medical use shown in Figure 1,
Fig. 5 is the skiagraph of the box in the container for medical use shown in Figure 1,
Fig. 6 is the front elevation that expression container for medical use shown in Figure 1 is in the partly cut-away that is communicated with the preceding state of operation,
Fig. 7 is that expression container for medical use shown in Figure 1 is in the front elevation that is communicated with the partly cut-away of operating the state after just having begun,
Fig. 8 is the front elevation that expression container for medical use shown in Figure 1 is in the partly cut-away of state when being communicated with EO,
Fig. 9 is the sectional drawing of the container for medical use of the second embodiment of the present invention,
Figure 10 is the axonometric chart of the container for medical use of the fourth embodiment of the present invention,
Figure 11 is the front elevation of the partly cut-away of container for medical use shown in Figure 10,
Figure 12 is the axonometric chart of the container for medical use of the fifth embodiment of the present invention,
Figure 13 is the sectional drawing of the container for medical use of the third embodiment of the present invention.
Below, with reference to accompanying drawing embodiments of the invention are described.
The container for medical use of Fig. 1-8 expression first embodiment of the present invention, wherein 1 be solution container, the 2nd, pharmaceutical vial, the 3rd has the box, the 4th of bottom tube-like, coupling part.
Solution container 1 is the flexible container that forms with materials such as thermoplastic polyolefin resin, soft Corvic, ethylene-vinyl acetate copolymers, the useful thin film 32(in top is referring to Fig. 6) envelope connector part 5 only, the medicinal liquid of the useful rubbery stopper sealing in bottom is discharged oral area 9, and solution in filling in the container.
Pharmaceutical vial 2 is oral area containers of pouring medicament into the rubbery stopper sealing.
The hollow connection tube 6 that forms one with the body of box 3 is arranged at the bottom of box 3.Upper end at box 3 also has flange, also has the support section 10 of suspender 7 and suspender on outer wall top, in addition, on substantial middle four positions partly of outer wall through hole 8 is being set also.Suspender 7 is being supported by the support section 10 that is arranged on the suspender on box 3 outer walls.
Coupling part 4 is made of above-mentioned connection tube 6 and connector part 5, and both are chimeric airtightly fastening.
Below, describe the structure of the foregoing description in detail according to Fig. 2-Fig. 6.As shown in Figure 2, pharmaceutical vial 2 is that its oral area 11 is down arranged, its oral area 11 is embedded in the recess 14 of fixed mount 13 of pharmaceutical vial, ring spacer 23 is contained in 12 li of the annular grooves that form on pharmaceutical vial 2 bottles circlewise, and ring spacer 24 is contained in 15 li of the annular grooves that form on the flange portion of fixed mount 13 of pharmaceutical vial circlewise.As mentioned above, the fixed mount 13 of pharmaceutical vial 2 and pharmaceutical vial by ring spacer 23,24 by airtightly and can be inserted in movably on the box 3.Between the fixed mount 13 of this pharmaceutical vial and box 3 bottoms, form airtight space, double needle 16 is being set in this confined space.
As shown in Figure 3, the blade face that makes double needle 16 opening portion 26 by usefulness is arranged in the bottom of the recess 14 of the fixed mount 13 of pharmaceutical vial, on the flange portion of the fixed mount 13 of pharmaceutical vial, at least one airport that connects up and down 25 is being set also.The material of the fixed mount 13 of pharmaceutical vial is the plastics of handy hard or rubber etc.In addition, also can make one to the ring spacer 24 and the fixed mount 13 of pharmaceutical vial.The material of ring spacer 24 is flexible plastic, silicone rubber, butadiene rubber, isoprene rubber etc. such as handy polystyrene.
As shown in Figure 4, double needle 16 has the wheel hub 27 on the middle part that is arranged on it, when the rubber stopper 30(of transfixation pharmaceutical vial oral area referring to Fig. 6) time, it can keep the transfixation degree of depth certain, also be useful on the pin this double needle 16 is fastened to 20 li of the annular grooves on box 3 inwalls, made with fastening part 17 and prevent leakage part 18.Materials such as stainless steel metal pin, duroplasts resin are the preferred materials of making double needle 16.
As shown in Figure 5, on three positions of the inwall of box 3, make annular groove 19,20,21; On the part of annular groove 20, make through hole 8.The connection tube 6 that is arranged on box 3 bottoms has a through hole 29 and coupling part rubber stopper (referring to Fig. 2) the 22nd, cooperates to be loaded on through hole 29, manage and 6 also have an interlocking groove 28, and the interlocking of the coupling part of solution container 1 with projection 31(referring to Fig. 6) be exactly to be embedded in the ditch 28.
As shown in Figure 6, the fixed mount 13 of pharmaceutical vial 2 and pharmaceutical vial is adjacent in annular groove 19 with ring spacer 23 respectively and the state that ring spacer 24 is adjacent to 20 li of annular grooves is inserted in the box 3.
As mentioned above, by the fixed mount 13 of pharmaceutical vial is inserted in the box 3, between the bottom of the fixed mount 13 of pharmaceutical vial and box 3, just form confined space, can prevent that by ring spacer 23 extraneous air from invading in the confined space, thereby guarantee the aseptic in the confined space.Embed the shift in position that just can prevent the fixed mount that makes the pharmaceutical vial in the box 3 13 that causes because of the vibration that in course of conveying, produces in the annular groove 19,20 respectively by two ring spacers 23,24.Ring spacer 24 is positioned on the through hole 8, and it is the shield that breaks away from by the bottom of pushing pharmaceutical vial 2.
Below, with reference to Fig. 7, Fig. 8 the using method of above-mentioned container for medical use is described.
Fig. 7 represents that pharmaceutical vial 2 and solution container 1 are being communicated with the state of operation after just having begun, and Fig. 8 represents to be communicated with the state behind the EO.For pharmaceutical vial 2 is communicated with solution container 1, earlier the bottom of pharmaceutical vial 2 is pressed downwards, more particularly, promptly with finger the bottom of pharmaceutical vial 2 to pressing down, the fixed mount 13 that makes pharmaceutical vial is to solution container 1 decline.By this operation two ring spacers 23,24 are come off from annular groove 19,20, when annular groove 20 came off, the through hole of by ring spacer 24 lockings 8 just was opened at ring spacer 24.
And then, air in the confined space in the box 3 that is dwindled by the decline of the fixed mount 13 of ampoule is just discharged outside box 3 from through hole 8 by air flow through hole 25, by this deflated effect, keeping the fixed mount 13 of the pharmaceutical vial of pharmaceutical vial 2 to be unlikely to regard to easy decline owing to the air in the confined space that has dwindled is pushed back.When the fixed mount 13 of pharmaceutical vial further when pressing down, the front end of the fastening part 17 of double needle 16 comes off from annular groove 21, double needle 16 descends to solution container 1.Thus just as shown in Figure 8, by double needle 16 instantaneously with the coupling part rubber stopper 22 of coupling part 4 and thin film 32 and in pharmaceutical vial oral area rubber stopper 30 transfixations of an opposite side.At this moment ring spacer 23 is embedded into 20 li of annular grooves, and through hole 8 bars up once more.Ring spacer 23 is embedded into 20 li of annular grooves in addition, and ring spacer 24 is embedded into 21 li of annular grooves, just prevents that thus the fixed mount 13 of pharmaceutical vial from rising.
Make after pharmaceutical vial 2 and solution container 1 be communicated with,, or solution container 1 is put also higher, push wall, solution is moved on in the pharmaceutical vial 2, medicament is dissolved than pharmaceutical vial 2 they maintenance levels.After treating that medicament dissolves fully, make solution get back to 1 li of solution container, suspender 7 is hung on the hook of drip stand, discharge on the oral area 9 at the medicinal liquid of solution container 1 and install infusion set, just can carry out intravenous drip the patient.
Fig. 9 represents the container for medical use of the second embodiment of the present invention.As shown in the figure, in the present embodiment, the outer wall of pharmaceutical vial fixed mount 13 extends to the tube portion of pharmaceutical vial 2 always; And in the present embodiment, in the tube portion of pharmaceutical vial 2, not disposing annular groove 12 and ring spacer 23, these are different with the container for medical use shown in Fig. 1-8.Be that the oral area of pharmaceutical vial 2 down is inserted in the fixed mount 13 of pharmaceutical vial airtightly in the present embodiment, on the outer wall of the fixed mount 13 of pharmaceutical vial, make annular groove, on the periphery of this annular groove, adorning ring spacer 33 annularly.
Adopt said structure just needn't in the tube portion of pharmaceutical vial 2, make annular groove 12, therefore can be normally used vial as pharmaceutical vial.
Structure in addition all is identical in fact with the embodiment shown in Fig. 1-8.
Figure 13 represents the container for medical use of the third embodiment of the present invention, and except the fastening part 17 of double needle 16 has replaced ring spacer 24 and plays a part the shielding through hole 8, other are all identical in fact with the container for medical use shown in Fig. 1-8.
Figure 10 and Figure 11 represent the container for medical use of the fourth embodiment of the present invention.
As shown in figure 11, the outer wall of the fixed mount 13 of the pharmaceutical vial of present embodiment extends to the bottom of pharmaceutical vial 2 always.Below the fixed mount 13 of this pharmaceutical vial, a flange portion is arranged, and also have the chimb part 34(that constitutes by outside chimb 37 with to inner raised edge 38 on the upper part of this frame 13 referring to Figure 10), and on the tube portion sidewall on the fixed mount 13 of the pharmaceutical vial of present embodiment, protuberance 35 is being set and at least two locational incision parts 36.Also on the tube portion inwall of the fixed mount 13 of the pharmaceutical vial of present embodiment, the ring spacer of being close to pharmaceutical vial 2 39 is being set.
The rising of the pharmaceutical vial 2 that causes when in the container for medical use of present embodiment, preventing by double needle 16 transfixation pharmaceutical vial oral area rubber stoppers 30 and thin film 32 and coupling part rubber stopper 22 by the protuberance 35 of making wedge shape to inner raised edge 38 and bottom on the fixed mount 13 that is arranged on pharmaceutical vial.The rising of this pharmaceutical vial 2 prevents by following manner, promptly when the connection operation by the bottom surface of pushing pharmaceutical vial 2 descends the fixed mount 13 of pharmaceutical vial, the protuberance 35 and the inwall of box 3 are joined, the upper portion side wall of the fixed mount 13 of pharmaceutical vial is out of shape to the inside towards the axle core, along with the distortion of sidewall, just the bottom of pharmaceutical vial 2 is pushed down to inner raised edge 38.
In addition, the container for medical use of present embodiment has the feature of easily refuse being handled respectively after use.After the container for medical use that uses present embodiment, the outside chimb 37 on fixed mount 13 upper ends that are arranged on pharmaceutical vial is just upwards drawn and can take out the fixed mount 13 of pharmaceutical vial from box 3.After the fixed mount 13 of pharmaceutical vial is taken out, just can take out the pharmaceutical vial the fixed mount 13 that is arranged on pharmaceutical vial 2 from the sidewall that incision part 36 pinches the pharmaceutical vial of exposing 2 with finger.
Being arranged on standard deviation that ring spacer 39 on the tube portion inwall of fixed mount 13 of pharmaceutical vial prevents the tube portion diameter of the pharmaceutical vial 2 that produced by mass production makes the interior air-tightness of box 3 influenced.And three ring spacers 24,33,39 that are arranged on the fixed mount 13 of pharmaceutical vial can be contained in after offering annular groove on the fixed mount 13 of pharmaceutical vial annularly, also can be integrally formed into the fixed mount 13 of pharmaceutical vial.
Figure 12 represents the medical container of the fifth embodiment of the present invention.
As shown in the figure, through hole 8 is arranged on the annular groove 21 of fixing double needle 16, and the shield of the standing part 17 of double needle 16 as the switch through hole.
Other structure is all identical in fact with the container for medical use shown in Figure 10,11.

Claims (6)

1, a kind of container for medical use, it comprises:
Sealed solution container is sealed the connector part with thin film;
The tubular box that the end is arranged, its bottom have the plug that is made of elastomeric material to seal, and in the bottom connection tube that connects in the above-mentioned connector part by being fitted to are arranged, simultaneously the tube portion of this box through hole that has aerofluxus to use;
The fixed mount that has flange, and at least one air flow through hole is being set on flange portion, the recess of its bottom is being provided with opening portion simultaneously, and this can be maintained in the above-mentioned box vertically movably;
Pharmaceutical vial, it can be in the said fixing frame be maintained at above-mentioned box movably under the oral area that the plug that is made of elastomeric material is sealed is embedded into state in the above-mentioned recess;
The hollow double needle, it can be maintained in the confined space that forms between the oral area of pharmaceutical vial and the above-mentioned tubular box bottom vertically movably, and be to make the above-mentioned box of energy transfixation, each plug of pharmaceutical vial and above-mentioned thin film, and this double needle also has a wheel hub, be normal value in order to keep the transfixation degree of depth;
First shield, following above-mentioned through hole of its state before with respect to box pharmaceutical vial being pressed into are closed and are kept the airtight conditions of above-mentioned confined space, and when with respect to box pharmaceutical vial being pressed into, break away from from above-mentioned through hole;
The secondary shielding body, with above-mentioned first shield above-mentioned confined space is maintained airtight conditions under its state before pharmaceutical vial being pressed into, above-mentioned through hole is closed during each plug of above-mentioned box, pharmaceutical vial and above-mentioned thin film transfixation certain depth and above-mentioned confined space is maintained airtight conditions at double needle with respect to above-mentioned box.
2, container for medical use as claimed in claim 1 it is characterized in that the first above-mentioned shield is arranged on the outer peripheral portion of above-mentioned fixed mount, and above-mentioned secondary shielding body is arranged on the outer peripheral portion of above-mentioned pharmaceutical vial.
3, container for medical use as claimed in claim 1 is characterized in that first, second above-mentioned shield is separately positioned on the outer peripheral portion of said fixing frame.
4, container for medical use as claimed in claim 1 is characterized in that the first above-mentioned shield is arranged on the peripheral edge portion of wheel hub of above-mentioned double needle.
5,, it is characterized in that above-mentioned fixed mount has as claim 3 or 4 described container for medical use: the outside chimb on the end of an opposite side with above-mentioned recess, in order to keep above-mentioned pharmaceutical vial bottom to inner raised edge and incision part.
6, container for medical use as claimed in claim 5 is characterized in that having when with respect to above-mentioned box pharmaceutical vial being pressed on the above-mentioned end of above-mentioned fixed mount, for the engaged at end of above-mentioned box, the below makes the outside ledge of wedge shape.
CN 93120852 1993-05-07 1993-12-15 container for medical use Pending CN1094608A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2924593U JPH0686738U (en) 1992-06-16 1993-05-07 Medical container
JP29245/93 1993-05-07

Publications (1)

Publication Number Publication Date
CN1094608A true CN1094608A (en) 1994-11-09

Family

ID=12270874

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 93120852 Pending CN1094608A (en) 1993-05-07 1993-12-15 container for medical use

Country Status (1)

Country Link
CN (1) CN1094608A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481228A (en) * 2009-09-08 2012-05-30 泰尔茂株式会社 Mixing apparatus and piercing method for a double-ended needle
CN102596753A (en) * 2009-09-14 2012-07-18 雀巢产品技术援助有限公司 Package with foil seals and penetrating means
CN102821735A (en) * 2010-03-30 2012-12-12 泰尔茂株式会社 Connector and connector assembly
CN106794932A (en) * 2014-08-27 2017-05-31 穆勒曼知识产权有限公司 The metering device being made of plastics

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102481228A (en) * 2009-09-08 2012-05-30 泰尔茂株式会社 Mixing apparatus and piercing method for a double-ended needle
CN102481228B (en) * 2009-09-08 2014-07-09 泰尔茂株式会社 Mixing apparatus and piercing method for a double-ended needle
CN102596753A (en) * 2009-09-14 2012-07-18 雀巢产品技术援助有限公司 Package with foil seals and penetrating means
CN102596753B (en) * 2009-09-14 2015-03-11 雀巢产品技术援助有限公司 Package with foil seals and penetrating means
CN102821735A (en) * 2010-03-30 2012-12-12 泰尔茂株式会社 Connector and connector assembly
CN102821735B (en) * 2010-03-30 2014-05-14 泰尔茂株式会社 Connector and connector assembly
CN106794932A (en) * 2014-08-27 2017-05-31 穆勒曼知识产权有限公司 The metering device being made of plastics
CN106794932B (en) * 2014-08-27 2019-05-03 穆勒曼知识产权有限公司 The metering device being made of plastics
US10315830B2 (en) 2014-08-27 2019-06-11 Mühlemann Ip Gmbh Metering device made of plastics material

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C06 Publication
PB01 Publication
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication