CN109394962A - A kind of drug for treating constipation - Google Patents

A kind of drug for treating constipation Download PDF

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Publication number
CN109394962A
CN109394962A CN201811471018.4A CN201811471018A CN109394962A CN 109394962 A CN109394962 A CN 109394962A CN 201811471018 A CN201811471018 A CN 201811471018A CN 109394962 A CN109394962 A CN 109394962A
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China
Prior art keywords
rheum officinale
liquid medicine
drug
pure rice
asparagus fern
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Pending
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CN201811471018.4A
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Chinese (zh)
Inventor
俞傲然
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Individual
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Individual
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Priority to CN201811471018.4A priority Critical patent/CN109394962A/en
Publication of CN109394962A publication Critical patent/CN109394962A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of drugs for treating constipation, the drug is prepared by following raw material: Radix Astragali, asparagus fern, Radix Ophiopogonis, rheum officinale, pure rice distilled spirit, the alcoholic strength of the pure rice distilled spirit is 45 degree, by can effectively treat constipation after taking the drug, the effect that can improve function of intestinal canal is taken for a long time.

Description

A kind of drug for treating constipation
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, and in particular to a kind of drug for treating constipation.
Background technique
Constipation is a kind of frequently-occurring disease, especially sees women, old man and children, and constipation can seriously affect the normal life of people It is living, unlimited pain can be brought, old people constipation is also possible to cause other diseases, such as cardiovascular and cerebrovascular disease, and constipation Often be difficult to cure, can permanent influence health of people, the main reason for constipation concludes are as follows: enteron aisle accumulated heat, toxin interference and Function of intestinal canal move back it is weak caused by, fundamentally to solve constipation, there is a two big main points, first: removing toxic substances heat-clearing, second: help large intestine increases The power of powerful intestines, there is enteron aisle colic pain after taking in many Tongbian capsules at present, and diarrhea is more than, and taking people for a long time will appear gas The states such as empty, out of strength, seriously affect daily life.
Summary of the invention
In order to overcome the deficiencies of the prior art, the present invention provides a kind of drug for treating constipation, can after the drug by taking Effectively treatment constipation, takes the effect that can improve function of intestinal canal for a long time.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of drug for treating constipation, the drug are prepared by following raw material: Radix Astragali, asparagus fern, Radix Ophiopogonis, rheum officinale, pure rice Distilled spirit, the alcoholic strength of the pure rice distilled spirit are 45 degree.
It is described treatment constipation drug the preparation method is as follows:
(1) Radix Astragali, asparagus fern, Radix Ophiopogonis are added into 45 degree of pure rice distilled spirits, are sealed, placed 30 days and process in backlight shady place After liquid medicine is made, in which: Radix Astragali, asparagus fern, the weight ratio of Radix Ophiopogonis be 1:1:1, Radix Astragali, asparagus fern, the weight summation of Radix Ophiopogonis with 45 degree The weight ratio of pure rice distilled spirit is 1:5;(2) above-mentioned brewed good liquid medicine is filtered, rheum officinale is cleaned and is dried, is being filtered The rheum officinale after drying is added in liquid medicine afterwards, the weight ratio of liquid medicine and rheum officinale is 1:2 after filtering, when liquid medicine is fully absorbed by rheum officinale Afterwards, powder sieving, filling capsule are played after the rheum officinale containing liquid medicine being dried.
Beneficial effects of the present invention: Radix Astragali has the effect of that tonifying Qi, hidroschesis, inducing diuresis to remove edema, removing toxic substances apocenosis, theory of traditional Chinese medical science are recognized For in lung and large intestine each other table, the ability of intestinal peristalsis declines, mainly caused by insufficiency of lung-QI,deficiency of lung-QI;Asparagus fern is cold in nature, sweet in flavor, has The effect of nourishing yin and clearing heat, moistening lung nourshing kidney, can effective relief of constipation, Radix Ophiopogonis is cold in nature, sweet in flavor, have nourishing Yin and promoting production of body fluid, moistening lung and clearing away the heart-fire, The effects of antiphlogistic antibacterial, rheum officinale bitter cold, nontoxic, returns spleen, stomach, large intestine, liver, pericardium channel, have heat and toxic materials clearing away, clearing heat-fire, Removing pattogenic heat from the blood and toxic material from the body, by stasis of blood latus rectum, the effect of removing dampness through diuresis and removing jaundice, pure rice distilled spirit, 45 degree of alcoholic strength, with disinfecting detoxifying, promoting blood circulation Effect.This capsule is considered from the basic reason of constipation, makes the comprehensive compatibility of each medicinal material and according to special preparation process, and capsule is taken Afterwards without colic pain, the more than phenomenon of no diarrhea, taking for a long time can promote raising function of intestinal canal, reach tonifying Qi, heat-clearing, removing toxic substances, improvement The effect of function of intestinal canal.
Clinical trial:
50 patients with constipation puzzlement are extracted, the age, instructions of taking was to take two at 3 points in daily afternoon between 40-60 years old Grain, adheres to taking one month.
Criterion of therapeutical effect: cure: constipation illness disappears, and observes 3 months without recurrence;Improve: constipation illness mitigates;It is invalid: disease Shape is without improvement.
It being observed through treatment, it is normal to take equal defecation of rear the next morning by 44 patients in patient, after treating a course for the treatment of, 48 Patient, equal normal defecation, statistical data: curing 48, improves 1, total effective rate 99%, without any side effect and bad anti- It answers, and patient's reaction body is healthy, face has improvement.
Specific embodiment
The embodiments given below are intended to further illustrate the invention, but is not to be construed as to the scope of the present invention Limitation, content still falls within this to some nonessential modifications and adaptations of the invention to those skilled in the art according to the present invention The protection scope of invention.
Embodiment: a kind of drug for treating constipation, the drug are prepared by following raw material: Radix Astragali, asparagus fern, wheat Winter, rheum officinale, pure rice distilled spirit, in which: Radix Astragali, asparagus fern, the mass ratio of Radix Ophiopogonis are 1:1:1, the wine of the pure rice distilled spirit Precision is 45 degree.
It is described treatment constipation drug the preparation method is as follows:
(1) Radix Astragali, asparagus fern, Radix Ophiopogonis are added into 45 degree of pure rice distilled spirits, are sealed, placed 30 days and process in backlight shady place After liquid medicine is made, in which: Radix Astragali, asparagus fern, the weight ratio of Radix Ophiopogonis be 1:1:1, Radix Astragali, asparagus fern, the weight summation of Radix Ophiopogonis with 45 degree The weight ratio of pure rice distilled spirit is 1:5;
(2) above-mentioned brewed good liquid medicine is filtered, rheum officinale is cleaned and is dried, be added in liquid medicine after filtration after drying Rheum officinale, the weight ratio of liquid medicine and rheum officinale is that 1:2 dries the rheum officinale containing liquid medicine after liquid medicine is fully absorbed by rheum officinale after filtering After beat powder sieving, filling capsule.

Claims (1)

1. a kind of drug for treating constipation, the drug are prepared by following raw material: Radix Astragali, asparagus fern, Radix Ophiopogonis, rheum officinale, pure Rice distilled spirit, the alcoholic strength of the pure rice distilled spirit are 45 degree;
It is described treatment constipation drug the preparation method is as follows:
(1) Radix Astragali, asparagus fern, Radix Ophiopogonis are added into 45 degree of pure rice distilled spirits, are sealed, placed 30 days and process in backlight shady place After liquid medicine is made, in which: Radix Astragali, asparagus fern, the weight ratio of Radix Ophiopogonis be 1:1:1, Radix Astragali, asparagus fern, the weight summation of Radix Ophiopogonis with 45 degree The weight ratio of pure rice distilled spirit is 1:5;
(2) above-mentioned brewed good liquid medicine is filtered, rheum officinale is cleaned and is dried, be added in liquid medicine after filtration after drying Rheum officinale, the weight ratio of liquid medicine and rheum officinale is that 1:2 dries the rheum officinale containing liquid medicine after liquid medicine is fully absorbed by rheum officinale after filtering After beat powder sieving, filling capsule.
CN201811471018.4A 2018-12-04 2018-12-04 A kind of drug for treating constipation Pending CN109394962A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811471018.4A CN109394962A (en) 2018-12-04 2018-12-04 A kind of drug for treating constipation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811471018.4A CN109394962A (en) 2018-12-04 2018-12-04 A kind of drug for treating constipation

Publications (1)

Publication Number Publication Date
CN109394962A true CN109394962A (en) 2019-03-01

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903316A (en) * 2006-07-31 2007-01-31 兰玉岐 Traditional Chinese medicine composition for eliminating-toxins and removing-fat, prepn. method therefor
CN101015603A (en) * 2007-02-01 2007-08-15 甘肃奇正藏药有限公司 Medicine composition with fat-reducing and bowel relaxing functions, preparing process and quality controlling means thereof
CN101129766A (en) * 2007-09-24 2008-02-27 北京艺信堂医药研究所 Chinese medicine preparation for treating constipation
CN102846727A (en) * 2012-09-24 2013-01-02 南京正亮医药科技有限公司 Processing method of rheum officinale
CN103520293A (en) * 2013-09-27 2014-01-22 甘肃扶正药业科技股份有限公司 Oral traditional Chinese medicine for improving and treating constipation
CN103948780A (en) * 2014-04-23 2014-07-30 通化万通药业股份有限公司 Medicine and capsule for treating constipation
CN104491095A (en) * 2014-12-25 2015-04-08 广西中医药大学第一附属医院 Traditional Chinese medicine composition and preparation method thereof
CN107029025A (en) * 2017-05-26 2017-08-11 庆阳敦博科技发展有限公司 A kind of processing method of rhubarb decoction pieces
CN108175780A (en) * 2018-03-22 2018-06-19 重庆泰尔森制药有限公司 A kind of concocting method of rheum officinale

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903316A (en) * 2006-07-31 2007-01-31 兰玉岐 Traditional Chinese medicine composition for eliminating-toxins and removing-fat, prepn. method therefor
CN101015603A (en) * 2007-02-01 2007-08-15 甘肃奇正藏药有限公司 Medicine composition with fat-reducing and bowel relaxing functions, preparing process and quality controlling means thereof
CN101129766A (en) * 2007-09-24 2008-02-27 北京艺信堂医药研究所 Chinese medicine preparation for treating constipation
CN102846727A (en) * 2012-09-24 2013-01-02 南京正亮医药科技有限公司 Processing method of rheum officinale
CN103520293A (en) * 2013-09-27 2014-01-22 甘肃扶正药业科技股份有限公司 Oral traditional Chinese medicine for improving and treating constipation
CN103948780A (en) * 2014-04-23 2014-07-30 通化万通药业股份有限公司 Medicine and capsule for treating constipation
CN104491095A (en) * 2014-12-25 2015-04-08 广西中医药大学第一附属医院 Traditional Chinese medicine composition and preparation method thereof
CN107029025A (en) * 2017-05-26 2017-08-11 庆阳敦博科技发展有限公司 A kind of processing method of rhubarb decoction pieces
CN108175780A (en) * 2018-03-22 2018-06-19 重庆泰尔森制药有限公司 A kind of concocting method of rheum officinale

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
徐明编著: "《实用对药》", 31 October 2007, 福建科学技术出版社 *
范颖等编著: "《中药药对配方理论及应用》", 31 October 2015, 辽宁科学技术出版社 *
覃荣等: "润肠通便合剂对小鼠胃排空的影响", 《云南中医中药杂志》 *

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Application publication date: 20190301

RJ01 Rejection of invention patent application after publication