CN109394841A - A kind of essence health promoting liquid and preparation method thereof for treating rheumatalgia pain - Google Patents
A kind of essence health promoting liquid and preparation method thereof for treating rheumatalgia pain Download PDFInfo
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- 239000007788 liquid Substances 0.000 title claims abstract description 37
- 230000036541 health Effects 0.000 title claims abstract description 32
- 230000001737 promoting effect Effects 0.000 title claims abstract description 28
- 208000002193 Pain Diseases 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000003814 drug Substances 0.000 claims abstract description 44
- 239000000463 material Substances 0.000 claims abstract description 25
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 20
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 20
- 244000268590 Euryale ferox Species 0.000 claims abstract description 20
- 235000006487 Euryale ferox Nutrition 0.000 claims abstract description 20
- 241001248610 Ophiocordyceps sinensis Species 0.000 claims abstract description 20
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 20
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 20
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 20
- 235000008434 ginseng Nutrition 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 239000000284 extract Substances 0.000 claims abstract description 13
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 12
- 238000011049 filling Methods 0.000 claims abstract description 10
- 238000001914 filtration Methods 0.000 claims abstract description 10
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 10
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 8
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 8
- 239000012530 fluid Substances 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 241000208340 Araliaceae Species 0.000 claims description 19
- 239000011521 glass Substances 0.000 claims description 14
- 239000012535 impurity Substances 0.000 claims description 12
- 238000007654 immersion Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- 230000008569 process Effects 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- 238000002791 soaking Methods 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 2
- 239000011505 plaster Substances 0.000 abstract description 6
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 description 5
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 4
- 239000004202 carbamide Substances 0.000 description 4
- 125000002632 imidazolidinyl group Chemical group 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 201000003068 rheumatic fever Diseases 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 206010057254 Connective tissue inflammation Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 208000000112 Myalgia Diseases 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 208000016247 Soft tissue disease Diseases 0.000 description 1
- 206010061372 Streptococcal infection Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 208000038016 acute inflammation Diseases 0.000 description 1
- 230000006022 acute inflammation Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 210000000544 articulatio talocruralis Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 208000018631 connective tissue disease Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- -1 imidazolidinyl ureas Chemical class 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/08—Solutions
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The present invention relates to the technical fields of rheumatism health, more particularly to a kind of essence health promoting liquid and preparation method thereof for treating rheumatalgia pain, it, which can be reduced, takes endo-medicine influence caused by patient body for long periods of time, and it is inconvenient to paste to avoid bring when using plaster, is easy the case where sliding；Raw material including following mass fraction: 5-8 parts of cordyceps sinensis；3-7 parts of ginseng；10-14 parts of safflower；12-17 parts of Gorgon fruit；6-8 parts of Radix Angelicae Sinensis；15-18 parts of Sodium Hyaluronate of 13-15 parts of Herba Epimedii；4-6 parts of imidazolidinyl urea；30-35 parts of alcohol, preparation method includes the following steps: (1) pretreatment of raw material；(2) raw material crushes；(3) decoction extracts；(4) medical fluid boils；(5) filtration treatment；(6) decoction is concentrated；(7) auxiliary material adds；(8) filling；(9) disinfection storage.
Description
Technical field
The present invention relates to the technical fields of rheumatism health, more particularly to a kind of for treating the essence health care of rheumatalgia pain
Liquid and preparation method thereof.
Background technique
It is well known that rheumatism be a kind of infringement joint, bone, muscle, based on blood vessel and related soft tissue or connective tissue
Disease fall ill how more covert and slow, the course of disease is longer and inclines mostly with heredity wherein most is autoimmune disease
To.Rheumatic arthritis is a kind of common acute or chronic connective tissue inflammation, and usually said rheumatic arthritis is wind
One of damp and hot main performance, clinic is characterized by migrans miserable, the red and swollen, pain in joint and muscle, with A group hemolytic
Streptococcal infection is related, and the factors such as cold, humidity can induce this disease, and lower limb large joint such as knee joint, ankle-joint are most often involved.
Arthralgia is the primary symptom of rheumatic arthritis, and general joint is likely to that pain occurs, with large joint by
Tire out most commonly seen, typically shows as symmetry, migrans pain, subside within usual acute inflammation symptoms last 2-4 weeks, a pass
Resolution of symptoms is saved, the symptom in another joint may occur in which again, also there are several joints while falling ill.
In recent years, innumerable by the patient of rheumatalgia pain, the treatment method of existing rheumatalgia pain is usually used
The method of endo-medicine or plaster controls and alleviates rheumatalgia pain, but since drug itself has certain toxin,
It takes endo-medicine for long periods of time to be easy to affect to patient body, and controls pain using the mode of plaster
When pain, since plaster itself pastes inconvenience, and easy landing etc. causes using effect poor.
Summary of the invention
In order to solve the above technical problems, the present invention, which provides one kind, can reduce and take endo-medicine for long periods of time to patient body
Caused by influence, and can be pasted to avoid bring when using plaster it is inconvenient, be easy the case where sliding for treating wind
Essence health promoting liquid of wet pain and preparation method thereof.
Of the invention a kind of for treating the essence health promoting liquid of rheumatalgia pain, the raw material including following mass fraction:
5-8 parts of cordyceps sinensis；
3-7 parts of ginseng；
10-14 parts of safflower；
12-17 parts of Gorgon fruit；
6-8 parts of Radix Angelicae Sinensis；
13-15 parts of Herba Epimedii；
15-18 parts of Sodium Hyaluronate；
4-6 parts of imidazolidinyl urea；
30-35 parts of alcohol.
Of the invention is a kind of for treating the essence health promoting liquid of rheumatalgia pain, it is preferred that the original including following mass fraction
Material:
6-7 parts of cordyceps sinensis；
4-5 parts of ginseng；
12-13 parts of safflower；
13-15 parts of Gorgon fruit；
7 parts of Radix Angelicae Sinensis；
14 parts of Herba Epimedii；
16-17 parts of Sodium Hyaluronate；
5 parts of imidazolidinyl urea；
32-33 parts of alcohol.
Of the invention is a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, comprising the following steps:
(1) pretreatment of raw material: cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are weighed respectively, and removes its surface
Impurity；
(2) raw material crushes: pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process；
(3) decoction extracts: smashed raw material being put into pot, and clear water submergence raw medicinal material is added, carries out extraction 2h；
(4) medical fluid boil: by after immersion medicinal material and its soaking water it is boiled, turn small fire carry out first time tanning, decoction is filtered out
It obtains boiling decoction for the first time, then clear water is added into pot and did not had medicinal material boiled, turn small fire and boil for the second time, decoction is filtered
Second of tanning decoction is obtained out；
(5) filtration treatment: first time tanning decoction and second of tanning decoction are mixed and carry out fine filtering, is removed therein miscellaneous
Matter obtains Chinese medicine extract；
(6) decoction is concentrated: Chinese medicine extract is evaporated concentration, the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made；
(7) auxiliary material adds: adding Sodium Hyaluronate and imidazolidinyl urea into obtained concentrated traditional Chinese medicine extracting solution, and adds thereto
Enter alcohol, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid；
(8) filling: the essence health promoting liquid that will be obtained is dispensed into Brown Glass Brown glass bottles and jars only and is packaged；
(9) it disinfection storage: carries out disinfection and processing and is put in storage to the Essence after filling.
It is of the invention a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, first in the step (4)
The time of secondary tanning is 1.5h, and the time of second of tanning is 2h.
Of the invention is a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, dense in the step (7)
Contracting Chinese medicine extract volume is 1.5 times of alcohol by volume.
Compared with prior art the invention has the benefit that essence health promoting liquid prepared by the present invention using cordyceps sinensis,
Ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are the important extracting solution of raw material, cooperation Sodium Hyaluronate, imidazolidinyl urea and alcohol
Use simultaneously, obtained medicament be liquid aqua, can directly be coated on patient affected part, the operation cumbersome without other, only
It need to gently massage until whole absorb, and infiltration rate is fast, while analgesic effect is good, it can be at any time according to patient's
Requirement uses, and is not limited by environmental factor, and without for oral administration, it is possible to reduce shadow of the toxicity of drug to patient itself
It rings, and inconvenient, easy the case where sliding can be pasted to avoid bring when using plaster.
Specific embodiment
With reference to embodiment, the embodiment of the present invention is furthur described in detail.Following embodiment is used for
Illustrate the present invention, but is not intended to limit the scope of the invention.
Embodiment 1
5 parts of cordyceps sinensis, 3 parts of ginsengs, 10 parts of safflowers, 12 portions of Gorgon fruits, 6 parts of Radix Angelicae Sinensis and 13 parts of Herba Epimedii are weighed respectively, and are removed
Pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process by the impurity on its surface, will
Smashed raw material is put into pot, and be added clear water submergence raw medicinal material, carry out extraction 2h, by after immersion medicinal material and its immersion
Water is boiled, turns the first time tanning that small fire carries out 1.5h, filters out to obtain tanning decoction for the first time for decoction, then addition is clear into pot
Water did not had medicinal material boiled, turns second of tanning that small fire carries out 2h, decoction is filtered out to obtain second of tanning decoction, will for the first time
It boils decoction and second of tanning decoction mixing carries out fine filtering, remove impurity therein, obtain Chinese medicine extract, by Chinese medicine
Extracting solution is evaporated concentration, and the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made, and the body of concentrated traditional Chinese medicine extracting solution
Product is 1.5 times of alcohol by volume, and 15 parts of Sodium Hyaluronates and 4 parts of imidazolidinyls are added into obtained concentrated traditional Chinese medicine extracting solution
Urea, then 30 parts of alcohol are added thereto, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid, obtained essence is protected
Strong liquid is dispensed into Brown Glass Brown glass bottles and jars only and is packaged, and is carried out disinfection and processing and is put in storage to the Essence after filling.
Embodiment 2
6 parts of cordyceps sinensis, 4 parts of ginsengs, 12 parts of safflowers, 13 portions of Gorgon fruits, 7 parts of Radix Angelicae Sinensis and 14 parts of Herba Epimedii are weighed respectively, and are removed
Pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process by the impurity on its surface, will
Smashed raw material is put into pot, and be added clear water submergence raw medicinal material, carry out extraction 2h, by after immersion medicinal material and its immersion
Water is boiled, turns the first time tanning that small fire carries out 1.5h, filters out to obtain tanning decoction for the first time for decoction, then addition is clear into pot
Water did not had medicinal material boiled, turns second of tanning that small fire carries out 2h, decoction is filtered out to obtain second of tanning decoction, will for the first time
It boils decoction and second of tanning decoction mixing carries out fine filtering, remove impurity therein, obtain Chinese medicine extract, by Chinese medicine
Extracting solution is evaporated concentration, and the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made, and the body of concentrated traditional Chinese medicine extracting solution
Product is 1.5 times of alcohol by volume, and 16 parts of Sodium Hyaluronates and 5 parts of imidazolidinyls are added into obtained concentrated traditional Chinese medicine extracting solution
Urea, then 32 parts of alcohol are added thereto, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid, obtained essence is protected
Strong liquid is dispensed into Brown Glass Brown glass bottles and jars only and is packaged, and is carried out disinfection and processing and is put in storage to the Essence after filling.
Embodiment 3
6.5 parts of cordyceps sinensis, 4.5 parts of ginsengs, 12.5 parts of safflowers, 14.5 portions of Gorgon fruits, 7 parts of Radix Angelicae Sinensis and 14 parts of excessive sheep are weighed respectively
The leaves of pulse plants, and the impurity on its surface is removed, pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are subjected to powder
Smashed raw material is put into pot by broken processing, and clear water submergence raw medicinal material is added, and extraction 2h is carried out, by the medicine after immersion
Material and its soaking water are boiled, turn the first time tanning that small fire carries out 1.5h, filter out to obtain tanning decoction for the first time for decoction, then to
Clear water is added in pot did not had medicinal material boiled, turns second of tanning that small fire carries out 2h, decoction is filtered out to obtain second of tanning medicine
First time tanning decoction and second of tanning decoction are mixed and carry out fine filtering, removed impurity therein, obtain Chinese medicine and mention by juice
Liquid is taken, Chinese medicine extract is evaporated concentration, the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made, and in concentration
The volume of medicament extracting solution is 1.5 times of alcohol by volume, and 16.5 parts of hyaluronic acids are added into obtained concentrated traditional Chinese medicine extracting solution
Sodium and 5 parts of imidazolidinyl ureas, then 32.5 parts of alcohol are added thereto, while cooperating stirring to be uniformly mixed it and obtaining essence health care
Obtained essence health promoting liquid is dispensed into Brown Glass Brown glass bottles and jars only and is packaged by liquid, is carried out disinfection place to the Essence after filling
It manages and is put in storage.
Embodiment 4
7 parts of cordyceps sinensis, 5 parts of ginsengs, 13 parts of safflowers, 15 portions of Gorgon fruits, 7 parts of Radix Angelicae Sinensis and 14 parts of Herba Epimedii are weighed respectively, and are removed
Pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process by the impurity on its surface, will
Smashed raw material is put into pot, and be added clear water submergence raw medicinal material, carry out extraction 2h, by after immersion medicinal material and its immersion
Water is boiled, turns the first time tanning that small fire carries out 1.5h, filters out to obtain tanning decoction for the first time for decoction, then addition is clear into pot
Water did not had medicinal material boiled, turns second of tanning that small fire carries out 2h, decoction is filtered out to obtain second of tanning decoction, will for the first time
It boils decoction and second of tanning decoction mixing carries out fine filtering, remove impurity therein, obtain Chinese medicine extract, by Chinese medicine
Extracting solution is evaporated concentration, and the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made, and the body of concentrated traditional Chinese medicine extracting solution
Product is 1.5 times of alcohol by volume, and 17 parts of Sodium Hyaluronates and 5 parts of imidazolidinyls are added into obtained concentrated traditional Chinese medicine extracting solution
Urea, then 33 parts of alcohol are added thereto, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid, obtained essence is protected
Strong liquid is dispensed into Brown Glass Brown glass bottles and jars only and is packaged, and is carried out disinfection and processing and is put in storage to the Essence after filling.
Embodiment 5
8 parts of cordyceps sinensis, 7 parts of ginsengs, 14 parts of safflowers, 17 portions of Gorgon fruits, 8 parts of Radix Angelicae Sinensis and 15 parts of Herba Epimedii are weighed respectively, and are removed
Pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process by the impurity on its surface, will
Smashed raw material is put into pot, and be added clear water submergence raw medicinal material, carry out extraction 2h, by after immersion medicinal material and its immersion
Water is boiled, turns the first time tanning that small fire carries out 1.5h, filters out to obtain tanning decoction for the first time for decoction, then addition is clear into pot
Water did not had medicinal material boiled, turns second of tanning that small fire carries out 2h, decoction is filtered out to obtain second of tanning decoction, will for the first time
It boils decoction and second of tanning decoction mixing carries out fine filtering, remove impurity therein, obtain Chinese medicine extract, by Chinese medicine
Extracting solution is evaporated concentration, and the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made, and the body of concentrated traditional Chinese medicine extracting solution
Product is 1.5 times of alcohol by volume, and 18 parts of Sodium Hyaluronates and 6 parts of imidazolidinyls are added into obtained concentrated traditional Chinese medicine extracting solution
Urea, then 35 parts of alcohol are added thereto, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid, obtained essence is protected
Strong liquid is dispensed into Brown Glass Brown glass bottles and jars only and is packaged, and is carried out disinfection and processing and is put in storage to the Essence after filling.
500 people of patient similar in situation is chosen, every 100 people is one group, respectively corresponds and makes using embodiment 1 to embodiment 5
The essence health promoting liquid obtained takes appropriate essence health promoting liquid coating obtained and affected part, and gently massage compares patient's up to absorbing
State obtains following data:
The essence health promoting liquid for treating rheumatalgia pain that the present invention produces is not suitable for pregnant woman, breast feeding women, children, baby children
Youngster and skin allergy person, and the essence health promoting liquid for treating rheumatalgia pain of the invention will be set and save in a cool and dry place,
Avoid direct sunlight.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the technical principles of the invention, several improvements and modifications, these improvements and modifications can also be made
Also it should be regarded as protection scope of the present invention.
Claims (5)
1. a kind of for treating the essence health promoting liquid of rheumatalgia pain, which is characterized in that the raw material including following mass fraction:
5-8 parts of cordyceps sinensis；
3-7 parts of ginseng；
10-14 parts of safflower；
12-17 parts of Gorgon fruit；
6-8 parts of Radix Angelicae Sinensis；
13-15 parts of Herba Epimedii；
15-18 parts of Sodium Hyaluronate；
4-6 parts of imidazolidinyl urea；
30-35 parts of alcohol.
2. as described in claim 1 a kind of for treating the essence health promoting liquid of rheumatalgia pain, which is characterized in that preferred, packet
Include the raw material of following mass fraction:
6-7 parts of cordyceps sinensis；
4-5 parts of ginseng；
12-13 parts of safflower；
13-15 parts of Gorgon fruit；
7 parts of Radix Angelicae Sinensis；
14 parts of Herba Epimedii；
16-17 parts of Sodium Hyaluronate；
5 parts of imidazolidinyl urea；
32-33 parts of alcohol.
3. a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, which comprises the following steps:
(1) pretreatment of raw material: cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are weighed respectively, and removes its surface
Impurity；
(2) raw material crushes: pretreated cordyceps sinensis, ginseng, safflower, Gorgon fruit, Radix Angelicae Sinensis and Herba Epimedii are carried out pulverization process；
(3) decoction extracts: smashed raw material being put into pot, and clear water submergence raw medicinal material is added, carries out extraction 2h；
(4) medical fluid boil: by after immersion medicinal material and its soaking water it is boiled, turn small fire carry out first time tanning, decoction is filtered out
It obtains boiling decoction for the first time, then clear water is added into pot and did not had medicinal material boiled, turn small fire and boil for the second time, decoction is filtered
Second of tanning decoction is obtained out；
(5) filtration treatment: first time tanning decoction and second of tanning decoction are mixed and carry out fine filtering, is removed therein miscellaneous
Matter obtains Chinese medicine extract；
(6) decoction is concentrated: Chinese medicine extract is evaporated concentration, the 1/3 of the concentrated traditional Chinese medicine extracting solution original volume made；
(7) auxiliary material adds: adding Sodium Hyaluronate and imidazolidinyl urea into obtained concentrated traditional Chinese medicine extracting solution, and adds thereto
Enter alcohol, while cooperating stirring to be uniformly mixed it and obtaining essence health promoting liquid；
(8) filling: the essence health promoting liquid that will be obtained is dispensed into Brown Glass Brown glass bottles and jars only and is packaged；
(9) it disinfection storage: carries out disinfection and processing and is put in storage to the Essence after filling.
4. as claimed in claim 3 a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, which is characterized in that
The time of tanning is 1.5h for the first time in the step (4), and the time of second of tanning is 2h.
5. as claimed in claim 3 a kind of for treating the preparation method of the essence health promoting liquid of rheumatalgia pain, which is characterized in that
Concentrated traditional Chinese medicine extracting liquid volume in the step (7) is 1.5 times of alcohol by volume.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112220881A (en) * | 2019-11-19 | 2021-01-15 | 于文娟 | Formula and processing technology of health-care traditional Chinese medicine for treating rheumatic pain |
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2018
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Non-Patent Citations (1)
| Title |
|---|
| 赵文静等: "淫羊藿的药理作用及临床应用研究进展", 《中医药信息》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112220881A (en) * | 2019-11-19 | 2021-01-15 | 于文娟 | Formula and processing technology of health-care traditional Chinese medicine for treating rheumatic pain |
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Application publication date: 20190301 |