CN109394566B - Mask essence for repairing blue light damage - Google Patents
Mask essence for repairing blue light damage Download PDFInfo
- Publication number
- CN109394566B CN109394566B CN201811559355.9A CN201811559355A CN109394566B CN 109394566 B CN109394566 B CN 109394566B CN 201811559355 A CN201811559355 A CN 201811559355A CN 109394566 B CN109394566 B CN 109394566B
- Authority
- CN
- China
- Prior art keywords
- percent
- blue light
- ceramide
- repairing
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
A facial mask essence for repairing blue light injury is composed of purified water, allantoin, dipropylene glycol, methyl glucitol polyether-20, PPG-24-glyceryl polyether-24, EDTA disodium, menthone, 1, 2-hexanediol, carbomer, arginine, sodium hyaluronate, hydroxyethyl cellulose, hydroxylated lecithin, creatine, carnosine and transparent ceramide inclusion, and has a repairing effect on skin irradiated by blue light.
Description
Technical Field
The patent relates to a facial mask essence for repairing blue light damage, and belongs to the technical field of cosmetics.
Technical Field
It is well known that it is important to protect the skin from UVB, UVA and IR radiation, but relatively speaking how the skin is subject to visible light damage, especially the high energy visible-blue light, has a negligible perception. The wavelength of blue Light is 400-500nm, near ultraviolet, and is the shortest wavelength of High-Energy Visible Light, also called High Energy Visible Light (HEVL). The artificial blue light comprises an artificial light source: fluorescent bulbs for energy saving, LED lamps and electronic devices such as cell phones, tablets and computers, televisions. Recent studies have shown that blue light also has a detrimental aspect, and the current reference to blue light pollution refers to exposure to "hyperlinked lifestyle" artificial blue light. For example, persistent exposure to blue light prior to bedtime has been associated with sleep disorders, melatonin disorders and premature eye failure, also known as "blue light hazard". The effects of visible light or high-energy visible HEV on skin cells mainly include: 1) increasing reactive oxygen species, inducing oxidative damage to the skin, 2) promoting secretion of inflammatory factors, inducing inflammatory cascades, accelerating skin aging, 3) delaying epidermal barrier repair, 4) mitochondrial DNA damage, and 5) consuming carotenoids in the dermis. Research has shown that 53% of smartphone users are expected to increase by 2020. 60% of people spend at least 6h per day on digital equipment, so our daily exposure to blue light far exceeds the time of direct exposure to UV radiation. The hot spot of consumer interest in China today "3C premature aging" includes Cities (air pollution), Computers (blue light) and Communications (radio radiation). Therefore, it is necessary to develop a raw material for cosmetics or a finished product for cosmetics having the efficacy of repairing blue light damage.
The damage of the blue light is repaired mainly from three aspects of enhancing the tissue vitality after the blue light irradiation, lightening the tissue damage after the blue light irradiation and resisting the oxide after the blue light irradiation. Creatine (creatine) is a nitrogenous organic acid naturally present in vertebrates and can assist in providing energy to muscle and nerve cells. It can provide energy quickly, the activities of human body are provided by ATP, i.e. adenosine triphosphate, the storage quantity of ATP in human body is very small, ATP is consumed quickly when in sports, and creatine can be quickly resynthesized into ATP to supply energy. The creatine can effectively increase the tissue activity of cells after blue light injury in the facial mask.
Carnosine is a dipeptide consisting of two amino acids, beta-alanine and L-histidine, scavenging reactive oxygen radicals formed by over-oxidation of fatty acids in cell membranes during oxidative stress.
Ceramide is a sphingolipid composed of sphingosine long-chain base and fatty acid. Ceramide (Ceramide) is a kind of phospholipids with Ceramide as skeleton, mainly comprising Ceramide phosphorylcholine and Ceramide phosphorylethanolamine, the phospholipids are the main components of cell membrane, 40-50% of sebum in horny layer is composed of Ceramide, Ceramide is the main part of intercellular matrix, and plays an important role in keeping moisture balance of horny layer. However, ceramide is easily crystallized and separated out in cosmetics, and affects the efficacy and stability. In the present invention, ceramide-containing transparent inclusion bodies containing 2% of wheat extract are used. The wheat extract mainly contains glycosphingolipid and digalactosyldiglyceride, and has the effects of stabilizing the stability and efficacy of ceramide in cosmetics.
Disclosure of Invention
The invention aims to develop mask essence for repairing blue light damage, which has a repairing effect on skin irradiated by blue light.
The mask essence for repairing the blue light damage is characterized by comprising the following components in parts by weight:
purifying water: 69.5 to 85 percent of the total weight of the mixture,
allantoin: 0.1 to 0.2 percent of,
dipropylene glycol: 5 to 10 percent of the total weight of the mixture,
methyl glucitol polyether-20: 0.5 to 1 percent of the total weight of the mixture,
PPG-24-Glycerol polyether-24: 0.5 to 1 percent of the total weight of the mixture,
disodium EDTA: 0.02 to 0.1 percent of,
xinxian ketone: 0.3 to 0.6 percent of,
1, 2-hexanediol: 0.3 to 0.6 percent of,
carbomer: 0.1 to 0.2 percent of,
arginine: 0.1 to 0.2 percent of,
sodium hyaluronate: 0.01 to 0.1 percent of,
hydroxyethyl cellulose: 0.01 to 0.1 percent of,
hydroxylated lecithin: 0.1 to 0.2 percent of,
creatine: 0.3 to 0.8 percent of,
carnosine: 0.1 to 0.4 percent of,
8 to 15 percent of transparent ceramide inclusion,
the sum of the weight percentages of the raw materials is 100 percent.
The facial mask essence for repairing the blue light injury is characterized in that the chemical formula of carnosine is beta-alanyl-L-histidine.
The mask essence for repairing the blue light injury is characterized in that the transparent ceramide is a ceramide inclusion body which wraps ceramide 2, ceramide 3 and ceramide 6, and the particle size of the ceramide inclusion body is 10-20 nm.
The mask essence for repairing the blue light injury is transparent ceramide, and contains 2 wt% of wheat extract.
Drawings
FIG. 1 is a graph of the effect of the tissue ability of the present invention.
Detailed Description
The present invention is further illustrated by the following specific examples, comparative examples, but it should be understood that these examples, comparative examples are for illustrative purposes only and are not to be construed as limiting the present invention in any way.
Example 1
A facial mask essence for repairing blue light injury comprises the following components in parts by weight:
purifying water: 69.5 to 85 percent
Allantoin: 0.1 percent of
Dipropylene glycol: 5 percent of
Methyl glucitol polyether-20: 0.5 percent
PPG-24-Glycerol polyether-24: 0.5 percent
Disodium EDTA: 0.02 percent
Xinxian ketone: 0.3 percent of
1, 2-hexanediol: 0.3 percent of
Carbomer: 0.1 percent of
Arginine: 0.1 percent of
Sodium hyaluronate: 0.01 percent
Hydroxyethyl cellulose: 0.01 percent
Hydroxylated lecithin: 0.1 percent of
Creatine: 0.3 percent of
Carnosine: 0.1 percent of
8 percent of transparent ceramide inclusion
Preparation of example 1:
1. adding carbomer, sodium hyaluronate, hydroxyethyl cellulose, menthocamphone, disodium EDTA and allantoin into dipropylene glycol, and stirring;
2. adding purified water into the mixture obtained in the step 1, and stirring until no particles exist;
3. stirring arginine to be in a viscous liquid state;
4. adding methyl glucitol polyether-20, PPG-24-glyceryl polyether-24, 1, 2-hexanediol, creatine, carnosine, transparent ceramide inclusion and hydroxylated lecithin, stirring, and discharging.
Example 2
A facial mask essence for repairing blue light injury comprises the following components in parts by weight:
purifying water: 69.5 to 85 percent
Allantoin: 0.15 percent
Dipropylene glycol: 7.5 percent
Methyl glucitol polyether-20: 0.75 percent
PPG-24-Glycerol polyether-24: 0.75 percent
Disodium EDTA: 0.05 percent
Xinxian ketone: 0.5 percent
1, 2-hexanediol: 0.5 percent
Carbomer: 0.15 percent
Arginine: 0.15 percent
Sodium hyaluronate: 0.05 percent
Hydroxyethyl cellulose: 0.05 percent
Hydroxylated lecithin: 0.15 percent
Creatine: 0.5 percent
Carnosine: 0.25 percent
12% of transparent ceramide inclusion;
preparation of example 2:
1. adding carbomer, sodium hyaluronate, hydroxyethyl cellulose, menthocamphone, disodium EDTA and allantoin into dipropylene glycol, and stirring;
2. adding purified water into the mixture obtained in the step 1, and stirring until no particles exist;
3. stirring arginine to be in a viscous liquid state;
4. adding methyl glucitol polyether-20, PPG-24-glyceryl polyether-24, 1, 2-hexanediol, creatine, carnosine, transparent ceramide inclusion and hydroxylated lecithin, stirring well, and discharging;
example 3
A facial mask essence for repairing blue light injury comprises the following components in parts by weight: purifying water: 69.5 to 85 percent
Allantoin: 0.20 percent
Dipropylene glycol: 10 percent of
Methyl glucitol polyether-20: 1 percent of
PPG-24-Glycerol polyether-24: 1 percent of
Disodium EDTA: 0.1 percent of
Xinxian ketone: 0.6 percent
1, 2-hexanediol: 0.6 percent
Carbomer: 0.20 percent
Arginine: 0.20 percent
Sodium hyaluronate: 0.10 percent
Hydroxyethyl cellulose: 0.10 percent
Hydroxylated lecithin: 0.20 percent
Creatine: 0.8 percent
Carnosine: 0.4 percent
15 percent of transparent ceramide inclusion
Preparation of example 3:
1. adding carbomer, sodium hyaluronate, hydroxyethyl cellulose, menthocamphone, disodium EDTA and allantoin into dipropylene glycol, and stirring;
2. adding purified water into the mixture obtained in the step 1, and stirring until no particles exist;
3. stirring arginine to be in a viscous liquid state;
4. adding methyl glucitol polyether-20, PPG-24-glyceryl polyether-24, 1, 2-hexanediol, creatine, carnosine, transparent ceramide inclusion and hydroxylated lecithin, stirring well, and discharging;
comparative example 1
A facial mask essence for repairing blue light injury comprises the following components in parts by weight:
purifying water: 69.5 to 85 percent
Allantoin: 0.20 percent
Dipropylene glycol: 10 percent of
Methyl glucitol polyether-20: 1 percent of
PPG-24-Glycerol polyether-24: 1 percent of
Disodium EDTA: 0.1 percent of
Xinxian ketone: 0.6 percent
1, 2-hexanediol: 0.6 percent
Carbomer: 0.20 percent
Arginine: 0.20 percent
Sodium hyaluronate: 0.10 percent
Hydroxyethyl cellulose: 0.10 percent
Hydroxylated lecithin: 0.20 percent
Preparation of comparative example 1:
1. adding carbomer, sodium hyaluronate, hydroxyethyl cellulose, menthocamphone, disodium EDTA and allantoin into dipropylene glycol, and stirring;
2. adding purified water into the mixture obtained in the step 1, and stirring until no particles exist;
3. stirring arginine to be in a viscous liquid state;
4. adding methyl glucitol polyether-20 and PPG-24-glyceryl polyether-24, stirring, and discharging;
the 4 sets of compositions prepared above were tested for the effect of repairing blue light damage using a 3D epidermal model (Epikutis). The specific test method is as follows:
preparation based on the EpiKutis blue light damage model: the recovered skin model Epikutis was transferred in groups to 24-well plates containing model culture fluid. Respectively sucking 25 μ L of examples 1-3 and comparative example 1 by using a pipette, adding the mixture on the surface of a skin model, and continuously irradiating for 8h under a blue light lamp in a super clean bench, wherein the height of the model from the lamp tube is about 5 cm. After irradiation, the test object on the surface of the model is wiped by a cotton swab, the surface moisture is wiped by the cotton swab, the cleaned skin model (3 per group) is transferred into a 6-hole plate, 0.9mL of culture solution is added into each hole, and the skin model is placed in an incubator at 37 ℃ and 5% CO2 and 95% relative humidity for incubation for 16 h.
TABLE 1 test grouping
Tissue viability assay based on the EpiKutis blue light injury model: after completion of incubation, 300. mu.L of MTT working solution (1mg/mL) was added to each well of a sterile 24-well plate, and the bottom surface culture solution residue was wiped off with a cotton swab, followed by label transfer to a 24-well plate containing MTT working solution. Incubate at 37 ℃ in an incubator with 5% CO2 and 95% relative humidity for 3h + -5 min. After the MTT incubation was complete, the MTT solution was gently aspirated from the well plate using a pipette tip. The plates were filled with DPBS solution and aspirated again, and the washing process was repeated a total of 3 times to ensure tissue drying on the last aspiration. After washing, the tissue bottom was wiped dry with absorbent paper, transferred to a new 24-well plate, and 2mL of isopropanol was added to the culture chamber to dissolve crystals produced by MTT. And a sealing film is adopted to seal the gap of the 24-hole plate, so that the final volume is prevented from being influenced by the volatilization of the isopropanol. The mixture was left to stand at 4 ℃ overnight to dissolve. After completion of the lysis, the tissue was pierced with a 200. mu.L tip to allow the lysate to flow from the tissue into the culture well. The punctured tissue was discarded and the solution was blown up and down in the culture wells at least 3 times to ensure uniform solution. OD was measured by reading in 96-well plates at 570nm with isopropanol as a blank.
Tissue morphology detection based on the EpiKutis blue light damage model: the incubated and cleaned skin model (3 per group) was cut with a scalpel ring, transferred to a 1.5mL EP tube, fixed with neutral formalin fixing solution for 24H, dehydrated with gradient ethanol, xylene-transparent, embedded with normal paraffin, sectioned and H & E stained. And taking a picture under a microscope for observation, and collecting the picture.
Superoxide dismutase (SOD) activity: collecting the incubated and cleaned models (6 in each group), adding 300 mu L of protein extracting solution, and collecting the upper protein solution after uniformly blowing. The BCA protein kit is used for concentration determination. The SOD activity of each group of samples was measured according to the SOD assay kit instructions.
The experimental results are as follows:
tissue viability: as shown in fig. 1, the tissue viability of the negative control group was significantly decreased compared to the blank control group, and the tissue viability of the positive control group was significantly increased compared to the negative control group, which demonstrates that the cell tissue viability is significantly decreased after blue light irradiation, and indicates that the experiment is effective. As seen from fig. 1, the tissue viability of comparative example 1 is substantially equal to that of the negative control, which indicates that comparative example 1 has no repairing effect under blue light irradiation, while the tissue viability of examples 1 to 3 is significantly increased compared to that of the negative control group, and the tissue viability is correspondingly increased along with the increase of the weight percentage of the creatine, the carnosine and the transparent ceramide inclusion, which indicates that the creatine, the carnosine and the transparent ceramide inclusion have repairing effect on the skin after blue light irradiation;
and (3) detecting tissue morphology: compared with the blank group BC, the number of the NC living Cell layers of the negative control group is reduced, the Cell nucleus of the living Cell layer is greatly shrunk, the tissue morphology is abnormal, and the number of the Sunburn cells is increased; compared with a negative control group NC, the number of the PC living Cell layers of the positive control group is increased, the nuclear shrinkage rate of the living Cell layers is reduced, the number of the Sunburn cells is reduced, and compared with a blank group, the structure has no significant difference, which indicates that the experiment is effective. Compared with negative control group NC, the number of Sunburn cells in examples 1-3 is reduced, the number of the living Cell layer is more than that of the negative control group NC, the nuclear shrinkage rate of the living Cell layer is low, and the tissue morphology is recovered. The number of the living cell layers and the nuclear shrinkage of the living cell layers of the comparative example 1 and the negative control group NC are not obviously different from the negative control group NC. The skin after blue light irradiation of examples 1-3 is shown to have a repairing effect;
superoxide dismutase (SOD) activity: compared with the blank group BC, the activity of the negative control group NC SOD is obviously reduced; compared with a negative control group NC, the activity of the positive control group PCSOD is obviously improved, and the experiment is proved to be effective. The SOD activities of examples 1-3 were significantly increased compared to the negative control group NC. Examples 1-3 the skin after blue light irradiation had a healing effect.
Claims (2)
1. The mask essence for repairing the blue light damage is characterized by comprising the following components in parts by weight:
purifying water: 69.5 to 85 percent of the total weight of the mixture,
allantoin: 0.1 to 0.2 percent of,
dipropylene glycol: 5 to 10 percent of the total weight of the mixture,
methyl glucitol polyether-20: 0.5 to 1 percent of the total weight of the mixture,
PPG-24-Glycerol polyether-24: 0.5 to 1 percent of the total weight of the mixture,
disodium EDTA: 0.02 to 0.1 percent of,
xinxian ketone: 0.3 to 0.6 percent of,
1, 2-hexanediol: 0.3 to 0.6 percent of,
carbomer: 0.1 to 0.2 percent of,
arginine: 0.1 to 0.2 percent of,
sodium hyaluronate: 0.01 to 0.1 percent of,
hydroxyethyl cellulose: 0.01 to 0.1 percent of,
hydroxylated lecithin: 0.1 to 0.2 percent of,
creatine: 0.3 to 0.8 percent of,
carnosine: 0.1 to 0.4 percent of,
transparent ceramide inclusion: 8 to 15 percent of the total weight of the mixture,
the transparent ceramide inclusion body is a ceramide inclusion body with the particle size of ceramide 2, ceramide 3 and ceramide 6 being 10-20nm, wherein the transparent ceramide inclusion body contains 2 wt% of wheat extract; the sum of the weight percentages of the raw materials is 100 percent.
2. The mask essence for repairing blue light damage according to claim 1, wherein the carnosine has a chemical formula of β -alanyl-L-histidine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811559355.9A CN109394566B (en) | 2018-12-19 | 2018-12-19 | Mask essence for repairing blue light damage |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811559355.9A CN109394566B (en) | 2018-12-19 | 2018-12-19 | Mask essence for repairing blue light damage |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109394566A CN109394566A (en) | 2019-03-01 |
| CN109394566B true CN109394566B (en) | 2021-10-08 |
Family
ID=65460028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811559355.9A Active CN109394566B (en) | 2018-12-19 | 2018-12-19 | Mask essence for repairing blue light damage |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109394566B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114948789B (en) * | 2022-05-10 | 2023-07-25 | 珠海冀百康生物科技有限公司 | SOD composition with blue light resisting effect and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016176485A1 (en) * | 2015-04-29 | 2016-11-03 | Petkoska Anka T | Antioxidant compositions and methods of protecting skin, hair and nails against high energy blue-violet light |
| CN107334686A (en) * | 2017-08-18 | 2017-11-10 | 广州丸美生物科技有限公司 | Skin matrix, preparation method and applications and cosmetics and preparation method thereof |
| CN107648074A (en) * | 2017-11-06 | 2018-02-02 | 诺斯贝尔化妆品股份有限公司 | Film before a kind of adornment |
| CN107648177A (en) * | 2017-11-13 | 2018-02-02 | 诺斯贝尔化妆品股份有限公司 | A kind of profit repairs facial mask for releiving for sensitive skin |
| CN107837199A (en) * | 2017-11-06 | 2018-03-27 | 诺斯贝尔化妆品股份有限公司 | A kind of colored drawing tencel facial mask |
| CN108635274A (en) * | 2018-07-26 | 2018-10-12 | 广州环亚化妆品科技有限公司 | A kind of photoprotective composition and its preparation method and application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10032964B4 (en) * | 2000-07-06 | 2017-10-12 | Beiersdorf Ag | Use of creatine in cosmetic or dermatological preparations |
-
2018
- 2018-12-19 CN CN201811559355.9A patent/CN109394566B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016176485A1 (en) * | 2015-04-29 | 2016-11-03 | Petkoska Anka T | Antioxidant compositions and methods of protecting skin, hair and nails against high energy blue-violet light |
| CN107334686A (en) * | 2017-08-18 | 2017-11-10 | 广州丸美生物科技有限公司 | Skin matrix, preparation method and applications and cosmetics and preparation method thereof |
| CN107648074A (en) * | 2017-11-06 | 2018-02-02 | 诺斯贝尔化妆品股份有限公司 | Film before a kind of adornment |
| CN107837199A (en) * | 2017-11-06 | 2018-03-27 | 诺斯贝尔化妆品股份有限公司 | A kind of colored drawing tencel facial mask |
| CN107648177A (en) * | 2017-11-13 | 2018-02-02 | 诺斯贝尔化妆品股份有限公司 | A kind of profit repairs facial mask for releiving for sensitive skin |
| CN108635274A (en) * | 2018-07-26 | 2018-10-12 | 广州环亚化妆品科技有限公司 | A kind of photoprotective composition and its preparation method and application |
Non-Patent Citations (1)
| Title |
|---|
| "QUANYING泉盈微驻颜精华液";广东美联臣生物科技有限公司;《http://ftba.nmpa.gov.cn:8181/ftban/itownet/hzp_ba/fw/pz.jsp?processid=20160416002514fvezc&nid=20160416002514fvezc》;20160427;第1-2页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109394566A (en) | 2019-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102600057A (en) | Human placenta stem cell extractive lyophilized powder as well as preparation method thereof and application thereof | |
| CN107326003B (en) | 3D model constructed in vitro by using serum-free culture solution and construction method thereof | |
| WO2021036146A1 (en) | Phototoxicity testing method based on reconstructed skin model | |
| Bae et al. | Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury | |
| CN109394566B (en) | Mask essence for repairing blue light damage | |
| CN103446184A (en) | Application of amniotic mesenchymal stem cells in preparation of medicine for prolonging life, health product or cosmetic | |
| CN105002133A (en) | Human umbilical cord blood stem cell extract, and preparation method and application thereof | |
| CN109846743B (en) | Moisturizing and repairing composition and preparation method and application thereof | |
| Yang et al. | Anti-inflammation and anti-apoptosis effects of pearl extract gel on UVB irradiation HaCaT cells | |
| Marchbank et al. | Reparative properties of the traditional Chinese medicine Cordyceps sinensis (Chinese caterpillar mushroom) using HT29 cell culture and rat gastric damage models of injury | |
| JP5892576B2 (en) | Method for producing epithelial reconstructed body and screening method using the epithelial reconstructed body | |
| Stepanov et al. | The peculiarities of low-dose ionizing radiation influence on muscles metabolism in experimental animals | |
| CN105331656B (en) | The preparation method of the hidden dinoflagellate exocellular polysaccharide of Kou Shi and the application of the exocellular polysaccharide | |
| CN114948789A (en) | SOD composition with high-efficiency blue light resisting effect and preparation method thereof | |
| CN113940909A (en) | Composition for regulating circadian rhythm and application thereof | |
| CN113855597A (en) | Antioxidant, anti-inflammatory and soothing repair composition, preparation method and application thereof | |
| CN110684714A (en) | Construction method of barrier function weakening model | |
| TW201739459A (en) | Polysaccharide extract of microalgae and extraction method thereof | |
| CN112245482A (en) | Application of composition containing active mica in preparing medicine for improving activity of intracellular superoxide dismutase | |
| KR101739480B1 (en) | Cell sheet transfer method using photosensitive materials | |
| CN109288721A (en) | A kind of facial mask liquid of the stem cell factor containing apple and preparation method thereof | |
| CN114366685B (en) | Preparation method and application of red clover isoflavone phytosterol liposome | |
| TWI838291B (en) | Use of extract of pilea microphylla for manufacturing anti-inflammatory preparations | |
| Kusumawardani et al. | Human gingival mesenchymal stem cells-lyosecretome attenuates adverse effect of hydrogen peroxide-induced oxidative stress on osteoblast cells | |
| US20220323536A1 (en) | Use of beta-l-aspartyl-l-arginine on senescent skin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |