CN109007371A - A kind of feed addictive and its application method improving pig disease resistance - Google Patents

A kind of feed addictive and its application method improving pig disease resistance Download PDF

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Publication number
CN109007371A
CN109007371A CN201811014205.XA CN201811014205A CN109007371A CN 109007371 A CN109007371 A CN 109007371A CN 201811014205 A CN201811014205 A CN 201811014205A CN 109007371 A CN109007371 A CN 109007371A
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Prior art keywords
feed addictive
feed
lysozyme
pig
plant extracts
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CN201811014205.XA
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Chinese (zh)
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江涛
杨震
潘瑞
周善菊
穆玉云
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SHANGHAI XINNONG FEED CO Ltd
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SHANGHAI XINNONG FEED CO Ltd
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Priority to CN201811014205.XA priority Critical patent/CN109007371A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The invention discloses a kind of feed addictives and its application method for improving pig disease resistance.Include in the feed addictive: coconut oil 30~35%, feed fat powder additive 10~15%, lysozyme 5~10%, plant extracts 1~3%, popcorn 44~54%.Additive amount of the feed addictive in boar food is 5~10kg/T, and the additive amount in pig starter feed is 2~5kg/T.The present invention uses the coconut oil containing MCT Oil, compatibility plant extracts cinnamic acid and Thymol, and lysozyme, using popcorn as carrier, the feed addictive being formulated can substitute the antibiotic in feed, under the premise of meeting taboo anti-requirement, the disease resistance of pig can be improved, reduce the infringement of bacterium, virus to body, and then improve the production performance of swinery;It, which is used in brood sow, can be improved its reproductive performance, and the speed of growth of piglet can be accelerated by being used in piglet.

Description

A kind of feed addictive and its application method improving pig disease resistance
Technical field
The invention belongs to field of feed, are related to a kind of pig feed additive, and in particular to a kind of raising pig is disease-resistant The feed addictive and its application method of ability.
Background technique
Pig Industry enterprise generally can all add feed addictive in pannage.Common ordinary nutritional feed adds Adding agent includes: vitamins additive (vitamin A, vitamine D3, vitamin E, Vitamin K3, vitamin B12, riboflavin, ammonia Change choline, niacin, calcium pantothenate, folic acid, biotin etc.), microelement kind additive (copper, iron, zinc, manganese, iodine, selenium, cobalt etc.), ammonia Base acids additive (lysine, methionine etc.).For the digestion and absorption function for promoting pig, some pig raising enterprises can also raise in pig Digestive enhancers (enzyme preparation, live bacteria agent, acidulant, probiotics etc.) is added in material.For the disease resistance and raising for improving pig The production performance of swinery, some pig raising enterprises can also add medicated feed additive in pannage, and (including antibiotic is such as: soil is mould Element, streptomysin, aureomycin etc., hormone such as: growth hormone, cortex hormone of aadrenaline, estrogen, progestational hormone, thyroid hormone Deng).
In the Chinese feed advance forum held in the recent period, agriculture rural area portion veterinary Bureau chief Feng Zhongwu is indicated, drug is raised Feed additives will all be exited in the year two thousand twenty.At the same time, agriculture rural area portion, which is announced, carried out for animals resist about 2018-2021 years Bacterium medicine specifies that cultivation end subtracts timetable anti-and that limit is anti-using the notice of minimizing action pilot work.The mankind pacify food Unprecedented degree has been arrived in the concern of full problem, strictly using antibiotic and other chemicals to prevent medicament residue etc. Harm is the necessary access of global aquaculture development, and is faced not as global aquaculture to intensive and large-scale development Break the status of increased disease and stress factor, forces people that must seek the substitute of antibiotic, to ensure people to food Safety requirements, while being ensured that animal safety, stable production.
Medium chain fatty acid refers to the fatty acid containing 8~12 carbon atoms composition carbochain, during it is just generated by glycerine esterification Chain fatty acid triglycerides (or medium chain triglyceride, MCT).Typical MCT refers to saturation Trivent OCG or saturation capric acid Triglycerides or the triglycerides of saturation caprylic-capric acid mixing.Medium chain triglyceride is only made of saturated fatty acid, freezing point It is low, it is at room temperature liquid, viscosity is small.It is entirely odorless, colourless transparency liquid compared with soybean oil.With common grease and Hydrogenated oil and fat is compared, and the content of medium chain triglyceride unsaturated fatty acid is extremely low, and oxidation stability is very good, and iodine number is no more than 0.5.It is primarily present in the vegetable oil such as coconut oil, unique physiology, the biochemical characteristic having, for solving the energy of early stage sucking pig Amount needs, while being also antibacterial, growth promoter the substitutes such as antibiotic.
Medium chain fatty acid antibacterial, antiviral mechanism include: first it can quickly enter the lipid of bacterial cell membrane Layer causes content loss, transport mechanism to be destroyed and plays the role of inhibiting bacterium by destruction bacterial cell membrane structure. Secondly, the Medium chain fatty acid molecule not dissociated can readily penetrate through microorganism wall.Acid molecule enters can solve into the cell From release H+, so that intracellular pH value is reduced to its index value or less.At this moment can these H+ be discharged as possible in cell, this is one A process extremely to consume energy will cause bacterial metabolism failure, eventually dead;Meanwhile dissociating H+After cause intraor extracellular biggish PH value gradient causes the death of " pH sensitive bacterial ";Moreover, the toxicity anionic aggregated after dissociation may also lead to carefully intracellular Bacterium is dead.In addition, medium chain fatty acid can inhibit the generation of comprising lipase of bacterial origin.Must have because bacterium will be attached on enteron aisle villus This enzyme participates in, so can play the role of that bacterium is inhibited to be attached to intestinal wall, is arranged bacterium by excrement to be conducive to enteron aisle Except external.Finally, medium chain fatty acid can inhibit gram-positive bacteria by uncoupling.
Summary of the invention
It is an object of the invention to: under the premise of national the year two thousand twenty feed medicated premix is forbidden to use, provide one kind The feed addictive and its application method of pig disease resistance are improved, which is matched based on MCT Oil 5 plant extracts, lysozyme can play the role of improving pig disease resistance, and then improve using popcorn as carrier The production performance of swinery.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of feed addictive improving pig disease resistance, by mass percentage, including following components:
The plant extracts is the plant extracts that main component is cinnamic acid and Thymol.
Further, above-mentioned feed addictive is prepared by following process: (1) extruding that will be measured Corn (bulk density < 300g/L) is put into mixing machine;(2) the feed fat powder additive measured, lysozyme, plant are added Extract;(3) raw material being added in above-mentioned two step is mixed, incorporation time 60s-120s;(4) use fueling injection equipment will The coconut oil measured is sprayed onto the material that previous step mixes;(5) it is mixed again, incorporation time 60s-120s; (6) finished product mixed is packaged.
Further, the coconut oil is commercial products, main component C12:0, content 43.8%.In coconut oil MCT Oil, especially C12 saturated fat acid glycerol three ester have certain antibacterial, anti-virus ability.
Further, the feed fat powder additive is feed fat powder powder-speed energy of German Pepsi U.S. company production, Main component is C8:0 and C10:0, and content is >=20%.
Further, the lysozyme is the pig lysozyme dimerization of Shanghai E.K.M Biotechnology Co., Ltd.'s production Body, lysozyme dimer content >=3%, enzyme activity >=50u/mg.
Further, the plant extracts is the plant extract of Jie Neng section (China) bioengineering Co., Ltd production Object-An Huihua, Contents of Main Components: cinnamic acid >=45g/kg, Thymol >=135g/kg.Grower pigs can be improved in cinnamic acid Lymphocyte quantity, reduce its fecal coli quantity and NH3, H2S discharge amount.Thymol can promote weanling pig Intestinal health.
The present invention also provides a kind of application methods of the feed addictive of above-mentioned raising pig disease resistance: the feed adds Adding addition usage amount of the agent in boar food is 5~10kg/T, and the addition usage amount in pig starter feed is 2~5kg/T.
Beneficial effects of the present invention:
The present invention uses MCT Oil (coconut oil), compatibility plant extracts (cinnamic acid, Thymol) And lysozyme, using popcorn as carrier, the feed addictive being formulated can substitute the antibiotic in feed, meet Under the premise of prohibiting anti-requirement, the disease resistance of pig can also be improved, the infringement of bacterium, virus to body is reduced, is used in Its reproductive performance can be improved in brood sow, and the speed of growth of piglet can be accelerated by being used in piglet.
Feed addictive of the invention, by the MCT Oil (coconut oil) with antibacterial, antivirus action, With the plant extracts cinnamic acid and Thymol with improvement intestinal health effect, and the bacteriolyze with promotion digestion Enzyme, reasonable compatibility together, can play the role of synergistic antibacterial, it is antiviral, be thus remarkably improved the disease-resistant energy of pig Power, and then improve the production performance of swinery.
Specific embodiment
Below with reference to specific embodiment, the invention will be further described, but does not limit the present invention:
Embodiment 1
A kind of feed addictive improving pig disease resistance, by mass percentage, including following components:
Above-mentioned feed addictive is prepared by following process: (1) popcorn (bulk density that will be measured < 300g/L) it puts into mixing machine;(2) the fast energy, lysozyme, An Huihua measured is added;(3) it will be added in above-mentioned two step Raw material mixed, incorporation time 60s;(4) coconut oil measured previous step is sprayed onto using fueling injection equipment to mix In good material;(5) it is mixed again, incorporation time 60s;(6) finished product mixed is packaged.
The coconut oil is market purchase gained, main component C12:0, content 43.8%.
The speed can be C8:0 and C10:0 for the feed fat powder powder of German Pepsi U.S. production, main component, content for >= 20%.
The lysozyme is the pig lysozyme dimer of Shanghai E.K.M Biotechnology Co., Ltd.'s production, lysozyme two Aggressiveness content >=3%, enzyme activity >=50u/mg.
The intelligent China of peace is the plant extracts of Jie Neng section (China) bioengineering Co., Ltd production, and main component is meat Cinnamic aldehyde >=45g/kg, Thymol >=135g/kg.
The application method of the feed addictive of above-mentioned raising pig disease resistance: the feed addictive is in boar food Additive capacity be 5~10kg/T, the additive capacity in pig starter feed is 2~5kg/T.
Three, product composition detects:
It is measured according to the detection method of before-mentioned products ingredient, obtaining moisture content is 10.25%, and gross protein value is 4.35%, crude fat content 32.3%, product is powdery.
Embodiment 2
A kind of feed addictive improving pig disease resistance, by mass percentage, including following components:
Above-mentioned feed addictive is prepared by following process: (1) popcorn (bulk density that will be measured < 300g/L) it puts into mixing machine;(2) the fast energy, lysozyme, An Huihua measured is added;(3) it will be added in above-mentioned two step Raw material mixed, incorporation time 80s;(4) coconut oil measured previous step is sprayed onto using fueling injection equipment to mix In good material;(5) it is mixed again, incorporation time 80s;(6) finished product mixed is packaged.
The coconut oil is market purchase gained, main component C12:0, content 43.8%.
The speed can be C8:0 and C10:0 for the feed fat powder powder of German Pepsi U.S. production, main component, content for >= 20%.
The lysozyme is the pig lysozyme dimer of Shanghai E.K.M Biotechnology Co., Ltd.'s production, lysozyme two Aggressiveness content >=3%, enzyme activity >=50u/mg.
The intelligent China of peace is the plant extracts of Jie Neng section (China) bioengineering Co., Ltd production, and main component is meat Cinnamic aldehyde >=45g/kg, Thymol >=135g/kg.
The application method of the feed addictive of above-mentioned raising pig disease resistance: the feed addictive is in boar food Additive capacity be 5~10kg/T, the additive capacity in pig starter feed is 2~5kg/T.
Three, product composition detects:
It is measured according to the detection method of before-mentioned products ingredient, obtaining moisture content is 10.34%, and gross protein value is 4.10%, crude fat content 33.2%, product is powdery.
Embodiment 3
A kind of feed addictive improving pig disease resistance, by mass percentage, including following components:
Above-mentioned feed addictive is prepared by following process: (1) popcorn (bulk density that will be measured < 300g/L) it puts into mixing machine;(2) the fast energy, lysozyme, An Huihua measured is added;(3) it will be added in above-mentioned two step Raw material mixed, incorporation time 120s;(4) coconut oil measured previous step is sprayed onto using fueling injection equipment to mix In good material;(5) it is mixed again, incorporation time 120s;(6) finished product mixed is packaged.
The coconut oil is market purchase gained, main component C12:0, content 43.8%.
The speed can be C8:0 and C10:0 for the feed fat powder powder of German Pepsi U.S. production, main component, content for >= 20%.
The lysozyme is the pig lysozyme dimer of Shanghai E.K.M Biotechnology Co., Ltd.'s production, lysozyme two Aggressiveness content >=3%, enzyme activity >=50u/mg.
The intelligent China of peace is the plant extracts of Jie Neng section (China) bioengineering Co., Ltd production, and main component is meat Cinnamic aldehyde >=45g/kg, Thymol >=135g/kg.
The application method of the feed addictive of above-mentioned raising pig disease resistance: the feed addictive is in boar food Additive capacity be 5~10kg/T, the additive capacity in pig starter feed is 2~5kg/T.
Three, product composition detects:
It is measured according to the detection method of before-mentioned products ingredient, obtaining moisture content is 10.45%, and gross protein value is 4.13%, crude fat content 36.2%, product is powdery.
Embodiment 4
A kind of feed addictive improving pig disease resistance, by mass percentage, including following components:
Above-mentioned feed addictive is prepared by following process: (1) popcorn (bulk density that will be measured < 300g/L) it puts into mixing machine;(2) the fast energy, lysozyme, An Huihua measured is added;(3) it will be added in above-mentioned two step Raw material mixed, incorporation time 90s;(4) coconut oil measured previous step is sprayed onto using fueling injection equipment to mix In good material;(5) it is mixed again, incorporation time 90s;(6) finished product mixed is packaged.
The coconut oil is market purchase gained, main component C12:0, content 43.8%.
The main component of the feed fat powder additive is C8:0 and C10:0, and content is >=20%.
The lysozyme is the pig lysozyme dimer of Shanghai E.K.M Biotechnology Co., Ltd.'s production, lysozyme two Aggressiveness content >=3%, enzyme activity >=50u/mg.
The main component of the plant extracts are as follows: cinnamic acid >=45g/kg, Thymol >=135g/kg.
The application method of the feed addictive of above-mentioned raising pig disease resistance: the feed addictive is in boar food Additive capacity be 5~10kg/T, the additive capacity in pig starter feed is 2~5kg/T.
Three, product composition detects:
It is measured according to the detection method of before-mentioned products ingredient, obtaining moisture content is 10.38%, and gross protein value is 4.09%, crude fat content 36.1%, product is powdery.
Application test example 1
Practical effect for the verifying present invention in the piglet stage, research and development centre test pig farm in subordinate and are fed Test selects 380 piglets to be tested altogether.
Control group: feeding addition ordinary nutritional feed addictive (containing vitamin, microelement, amino acid) and digestion promote Into the feed of agent (enzyme preparation, acidulant, probiotics).
Test group: feeding addition ordinary nutritional feed addictive (containing vitamin, microelement, amino acid) and the present invention The feed of the feed addictive (containing coconut oil, cinnamic acid, Thymol, lysozyme) of embodiment 1.5kg is added in feed per ton The feed addictive of the embodiment of the present invention 1.
Piglet stage (24-70d) production performance compares
24d counterpoise kg 70d counterpoise kg Average daily gain g Average daily gain g Feedstuff-meat ratio Survival rate
Control group 7.21±0.48 27.71±1.61 715.37±43.24 445.65±12.13 1.57±0.05 98.53%
Test group 7.19±0.51 28.63±1.85 699.14±32.15 466.09±14.36 1.50±0.06 100%
Compared with the control group: 1, average daily gain: the daily ingestion amount organized of the addition present invention is averaged low 16.23g;2, average Daily gain: the daily gain for adding the test group of feed addictive of the invention is averagely higher by 20.44g;3, feedstuff-meat ratio: this hair is added The feedstuff-meat ratio of the test group of bright feed addictive average low 0.07;4, survival rate: the examination of feed addictive of the invention is added Test the high survival rate 1.47% of group.
It can be seen that feed addictive of the invention uses in baby pig feedstuff, the life of 24-70 age in days stage piglet is improved Produce performance and survival rate.
Application test example 2
Practical effect for the verifying present invention in the boar stage, research and development centre test pig farm in subordinate and are fed Test selects 70 gestation, 84 days sows to be tested altogether.
Control group: feeding addition ordinary nutritional feed addictive (containing vitamin, microelement, amino acid) and digestion promote Into the feed of agent (enzyme preparation, active bacteria formulation, acidulant).
Test group: feeding addition ordinary nutritional feed addictive (containing vitamin, microelement, amino acid) and the present invention The feed of the feed addictive (containing coconut oil, cinnamic acid, Thymol, lysozyme) of embodiment 2.10kg is added in feed per ton The feed addictive of the embodiment of the present invention 2.
Boar stage (pregnant 84d- wean) reproductive performance compares
Compared with the control group: 1,24d weight of weaning litter: the weight of weaning litter for adding the test group of feed addictive of the invention mentions High 8.42kg;2,7 days breeding rates after weaning: the breeding rate for adding the test group of feed addictive of the invention improves 5.71%. It can be seen that feed addictive of the invention uses in boar, its reproductive performance is improved, and have good rush with rate to disconnected Into effect.

Claims (9)

1. a kind of feed addictive for improving pig disease resistance, which is characterized in that by mass percentage, including with the following group Point:
The plant extracts is the plant extracts that main component is cinnamic acid and Thymol.
2. feed addictive according to claim 1, it is characterised in that: the feed addictive is by following process It is prepared: (1) putting into the popcorn measured in mixing machine;(2) the feed fat powder addition measured is added Agent, lysozyme, plant extracts;(3) raw material being added in above-mentioned two step is mixed, incorporation time 60s-120s;(4) The coconut oil measured is sprayed onto the material that previous step mixes using fueling injection equipment;(5) it is mixed again, when mixing Between be 60s-120s.
3. feed addictive as claimed in claim 2, it is characterised in that: in step (1), the bulk density < 300g/ of popcorn L。
4. feed addictive as claimed in claim 1,2 or 3, it is characterised in that: the main component C12:0 of the coconut oil, Content is 43.8%.
5. feed addictive as claimed in claim 1,2 or 3, it is characterised in that: the feed fat powder additive is Germany The feed fat powder powder of Pepsi U.S. production-speed energy, main component are C8:0 and C10:0, and content is >=20%.
6. feed addictive as claimed in claim 1,2 or 3, it is characterised in that: the lysozyme is Shanghai Ai Kui English biology The pig lysozyme dimer of Science and Technology Ltd.'s production, lysozyme dimer content >=3%, enzyme activity >=50u/mg.
7. feed addictive as claimed in claim 1,2 or 3, it is characterised in that: the plant extracts be Jie Neng section (in State) bioengineering Co., Ltd production plant extracts-An Huihua, main component: cinnamic acid >=45g/kg, Thymol >= 135g/kg。
8. a kind of application method of the feed addictive as claimed in claim 1 for improving pig disease resistance, special Sign is that addition usage amount of the feed addictive in boar food is 5~10kg/T, and the addition in pig starter feed makes Dosage is 2~5kg/T.
9. a kind of preparation method of the feed addictive as claimed in claim 1 for improving pig disease resistance, special Sign is, sequentially includes the following steps: (1) and puts into the popcorn measured in mixing machine;(2) function of measuring is added Property fat additives, lysozyme, plant extracts;(3) raw material being added in above-mentioned two step is mixed, incorporation time is 60s-120s;(4) coconut oil measured is sprayed onto the material that previous step mixes using fueling injection equipment;(5) again into Row mixing, incorporation time 60s-120s;(6) finished product mixed is packaged.
CN201811014205.XA 2018-08-31 2018-08-31 A kind of feed addictive and its application method improving pig disease resistance Pending CN109007371A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020058225A1 (en) * 2018-09-17 2020-03-26 Dsm Ip Assets B.V. Animal feed compositions and uses thereof
CN111340642A (en) * 2020-03-18 2020-06-26 浙江省动物疫病预防控制中心 Antibacterial drug use reduction measurement and calculation method in livestock and poultry breeding process
CN111657407A (en) * 2020-05-14 2020-09-15 上海艾魁英生物科技有限公司 Feed additive for improving non-specific immune function of weaned piglets and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102265984A (en) * 2011-08-03 2011-12-07 北京大北农科技集团股份有限公司 Feed for early weaned piglets
CN106509365A (en) * 2016-10-28 2017-03-22 上海申亚动物保健品阜阳有限公司 Essential oil energy emulsion feed additive for drinking water, preparation and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102265984A (en) * 2011-08-03 2011-12-07 北京大北农科技集团股份有限公司 Feed for early weaned piglets
CN106509365A (en) * 2016-10-28 2017-03-22 上海申亚动物保健品阜阳有限公司 Essential oil energy emulsion feed additive for drinking water, preparation and use thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020058225A1 (en) * 2018-09-17 2020-03-26 Dsm Ip Assets B.V. Animal feed compositions and uses thereof
CN111340642A (en) * 2020-03-18 2020-06-26 浙江省动物疫病预防控制中心 Antibacterial drug use reduction measurement and calculation method in livestock and poultry breeding process
CN111340642B (en) * 2020-03-18 2023-06-30 浙江省动物疫病预防控制中心 Method for measuring and calculating use reduction of antibacterial agent in livestock and poultry breeding process
CN111657407A (en) * 2020-05-14 2020-09-15 上海艾魁英生物科技有限公司 Feed additive for improving non-specific immune function of weaned piglets and preparation method and application thereof

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