CN108815470A - A kind of postoperative cracked Chinese medicine of improvement thyroid cancer - Google Patents

A kind of postoperative cracked Chinese medicine of improvement thyroid cancer Download PDF

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Publication number
CN108815470A
CN108815470A CN201810992386.7A CN201810992386A CN108815470A CN 108815470 A CN108815470 A CN 108815470A CN 201810992386 A CN201810992386 A CN 201810992386A CN 108815470 A CN108815470 A CN 108815470A
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China
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radix
chinese medicine
postoperative
thyroid cancer
rhizoma
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Inventor
燕树勋
王颖
燕翔
刘元炜
党辉
潘研
万红
王萍
郭盼盼
陈玲
余丹丹
燕苗苗
燕炳墨
万会娜
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Abstract

The purpose of the present invention is just to provide a kind of postoperative cracked Chinese medicine of improvement thyroid cancer, the Chinese medicine by:Radix rehmanniae recen, radix scrophulariae, Radix Ophiopogonis, campanulaceae, Radix Glycyrrhizae, Fructus Aurantii, Oroxylum indicum, cicada slough, myrobalan, great burdock achene, Radix Isatidis, endothelium corneum gigeriae galli, Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae, dried orange peel, the tuber of pinellia, fritillaria, radix ranunculi ternati, rhizoma dioscoreae nipponicae, oldenlandia diffusa, edible tulip, three shuttles, curcuma zedoary, Ramulus euonymi, turtle shell, rheum officinale, scorpio and insects are made, above-mentioned Chinese medicine is mixed, add water, it impregnates, it boils by intense fire, it uses instead and is cooked by slow fire, filtering, obtain the first filtrate, filter residue adds water, it boils by intense fire, it uses instead and is cooked by slow fire, filtering, obtain the second filtrate, it filtrate will be uniformly mixed twice, it is concentrated into 200-300ml, pure Chinese medicine of the present invention is prepared, the promoting flow of qi and blood circulation, sound relieving sore-throat is opened in resolving sputum, pleasant dredging collateral and antipyretic and antidote functions can be effectively improved the postoperative hoarseness symptom of thyroid cancer, it is the innovation on thyroid cancer postoperative rehabilitation drug.

Description

A kind of postoperative cracked Chinese medicine of improvement thyroid cancer
Technical field
The present invention relates to Chinese medicine, especially a kind of postoperative cracked Chinese medicine of improvement thyroid cancer.
Background technique
Thyroid cancer is the more typical malignant tumour of incidence, accounts for l%~2% of whole body malignant tumour, common with women, can See any age bracket.The disease incidence of thyroid cancer is in the trend significantly risen year by year at present.Thyroid cancer is divided into mamillary gland The multiple types such as cancer, filter blocking cancer, undifferentiated carcinoma, cephaloma.Wherein papillary carcinoma clinic is most common, accounts for the 50% of thyroid cancer ~70%.The treatment method of thyroid cancer has operative treatment, radiotherapy, chemotherapy, endocrine therapy and traditional Chinese medicine treatment Deng.At present " operation+131I treatment+thyroid hormone inhibits " it is acknowledged as the best comprehensive therapeutic plan of papillary carcinoma, it can drop The incidence of low recurrence or transfer.Since papillary carcinoma belongs to low-grade malignant tumor, patient can usually ignore postoperative rehabilitation and control It treats, operation can only cut off visible carcinoma, but can not eliminate carcinoma to damage caused by human body, and papillary carcinoma is postoperative in original Operative site recurrence rate is higher.Therefore the postoperative rehabilitation of papillary carcinoma should cause the attention of height.Current more and more evidences Show that postoperative traditional Chinese medicine treatment can improve itself bring adverse reaction of performing the operation;Immunity is improved, the postoperative health of patient is accelerated It is multiple;Mitigate the adverse reaction of oral thyroid plain piece;Soften the postoperative neck protrusion scar of thyroid cancer;It is secondary anti-to mitigate chemotherapy It answers;Inhibit thyroglobulin, reduces Serum Thyroglobulin, prevent and delay the recurrence and transfer of thyroid cancer Deng.L thyroxine tab is because of the originals such as the exposure for a long time of operation wound, visual area, anesthesia influence, trachea cannula loss, operation position Cause be easy to cause the complication such as hoarse patient's sound, expiratory dyspnea and asphyxia, and wherein hoarseness is most commonly seen symptom; Clinic mostly uses the hoarseness symptom of western medicine therapy alleviation L thyroxine tab patient, such as hydrocortisone sodium succinate hormone The nerve of the reparations such as the neurotrophy medicines such as class drug, methylcobalamin tablet and vitamin B1 damage, and then improve nervous function, and press down The further development of inflammation processed reaches detumescence and other effects, but some patients have stiff sputum and are attached to vocal cords and cause interstitial Property oedema, oozing of blood accumulation and inflammatory exudation under mucous membrane, and then cause permanent hoarseness or cry out, it is difficult to it is fully up to expectations, Therefore the innovation on drug is imperative.
Summary of the invention
For above situation, for the defect for solving the prior art, the purpose of the present invention is just to provide a kind of improvement thyroid gland The postoperative cracked Chinese medicine of cancer can be effectively improved the postoperative cracked symptom of thyroid cancer, accelerate postoperative rehabilitation, improve and suffer from The problem of person's quality of life.
The technical solution that the present invention solves is that the Chinese medicine is by poidometer:Radix rehmanniae recen 10-20g, radix scrophulariae 10-20g, Radix Ophiopogonis 10-20g, campanulaceae 6-15g, Radix Glycyrrhizae 6-15g, Fructus Aurantii 10-20g, Oroxylum indicum 10-20g, cicada slough 6-15g, myrobalan 10-20g, fructus arctii Sub- 10-20g, Radix Isatidis 20-30g, endothelium corneum gigeriae galli 20-30g, Rhizoma Chuanxiong 10-20g, Rhizoma Atractylodis Macrocephalae 10-20g, dried orange peel 10-20g, tuber of pinellia 9- 15g, fritillaria 10-20g, radix ranunculi ternati 20-30g, rhizoma dioscoreae nipponicae 10-20g, oldenlandia diffusa 15-25g, edible tulip 15-25g, three shuttles 10-20g, curcuma zedoary 10-20g, Ramulus euonymi 15-30g, turtle shell 10-20g, rheum officinale 6-20g, scorpio 6-15g and insects 10-20g system At, wherein above-mentioned Chinese medicine is mixed, the water of 6-8 times of Chinese medicine weight is added, half an hour is impregnated, boils by intense fire, use mild fire instead It decocts 30 minutes, filtering obtains the first filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, boils by intense fire, uses instead and is cooked by slow fire 30 points Clock, filtering, obtains the second filtrate, filtrate will be uniformly mixed twice, and be concentrated into 200-300ml.
Pure Chinese medicine of the present invention is prepared, and sound relieving sore-throat, pleasant dredging collateral and antipyretic and antidote functions are opened in the promoting flow of qi and blood circulation, resolving sputum to be had Effect improves the postoperative hoarseness symptom of thyroid cancer, and drug safety accelerates patient postoperative rehabilitation, improves patients ' life quality, It is the innovation on thyroid cancer postoperative rehabilitation drug.
Specific embodiment
Below in conjunction with concrete condition and embodiment, specific embodiments of the present invention will be described in further detail.
Embodiment 1
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 13-17g, it is profound Join 13-17g, Radix Ophiopogonis 12-18g, campanulaceae 8-13g, Radix Glycyrrhizae 8-13g, Fructus Aurantii 13-17g, Oroxylum indicum 13-17g, cicada slough 8-13g are scolded Sub- 13-17g, great burdock achene 13-17g, Radix Isatidis 23-27g, endothelium corneum gigeriae galli 23-27g, Rhizoma Chuanxiong 13-17g, Rhizoma Atractylodis Macrocephalae 13-17g, dried orange peel 13- 17g, tuber of pinellia 11-13g, fritillaria 13-17g, radix ranunculi ternati 22-28g, rhizoma dioscoreae nipponicae 13-17g, oldenlandia diffusa 18-22g, edible tulip 18-22g, three shuttle 13-17g, curcuma zedoary 13-17g, Ramulus euonymi 18-27g, turtle shell 13-17g, rheum officinale 9-17g, scorpio 8-13g and Qiang Dung beetle worm 13-17g is made, wherein mixes above-mentioned Chinese medicine, adds the water of 6-8 times of Chinese medicine weight, impregnates half an hour, intense fire It boils, uses instead and be cooked by slow fire 30 minutes, filter, obtain the first filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, boils by intense fire, uses instead It is cooked by slow fire 30 minutes, filters, obtain the second filtrate, filtrate will be uniformly mixed twice, and be concentrated into 200-300ml.
Embodiment 2
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:The Chinese medicine is by poidometer 's:Radix rehmanniae recen 15g, radix scrophulariae 15g, Radix Ophiopogonis 15g, campanulaceae 11g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 15g, cicada slough 11g, myrobalan 15g, great burdock achene 15g, Radix Isatidis 25g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 15g, Rhizoma Atractylodis Macrocephalae 15g, dried orange peel 15g, tuber of pinellia 12g, fritillaria 15g, cat Pawl grass 25g, rhizoma dioscoreae nipponicae 15g, oldenlandia diffusa 20g, edible tulip 20g, three shuttle 15g, curcuma zedoary 15g, Ramulus euonymi 22g, turtle shell 15g, Rheum officinale 13g, scorpio 11g and insects 15g are made, and the preparation method is the same as that of Example 1.
Embodiment 3
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 12g, radix scrophulariae 12g, Radix Ophiopogonis 12g, campanulaceae 10g, Radix Glycyrrhizae 6g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 10g, myrobalan 15g, great burdock achene 15g, Radix Isatidis 20g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 10g, dried orange peel 15g, tuber of pinellia 10g, fritillaria thunbergii 15g, radix ranunculi ternati 30g, rhizoma dioscoreae nipponicae 20g, Oldenlandia diffusa 25g, edible tulip 25g, three shuttle 12g, curcuma zedoary 12g, Ramulus euonymi 30g, turtle shell 12g, rheum officinale 6g, scorpio 6g and dung beetle Worm 20g is made, and the preparation method is the same as that of Example 1.
Embodiment 4
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 15g, radix scrophulariae 12g, Radix Ophiopogonis 12g, campanulaceae 8g, Radix Glycyrrhizae 12g, Fructus Aurantii 12g, Oroxylum indicum 15g, cicada slough 8g, myrobalan 12g, great burdock achene 12g, Radix Isatidis 25g, endothelium corneum gigeriae galli 30g, Rhizoma Chuanxiong 15g, Rhizoma Atractylodis Macrocephalae 15g, dried orange peel 12g, tuber of pinellia 12g, fritillaria thunbergii 12g, radix ranunculi ternati 20g, rhizoma dioscoreae nipponicae 15g, Oldenlandia diffusa 18g, edible tulip 18g, three shuttle 15g, curcuma zedoary 15g, Ramulus euonymi 25g, turtle shell 15g, rheum officinale 10g, scorpio 8g and Qiang Dung beetle worm 20g is made, and the preparation method is the same as that of Example 1.
Embodiment 5
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 18, radix scrophulariae 18g, Radix Ophiopogonis 15g, campanulaceae 12g, Radix Glycyrrhizae 15g, Fructus Aurantii 20g, Oroxylum indicum 12, cicada slough 12g, myrobalan 10g, great burdock achene 10g, Radix Isatidis 20g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 12g, Rhizoma Atractylodis Macrocephalae 12g, dried orange peel 12g, tuber of pinellia 10g, fritillaria thunbergii 15g, radix ranunculi ternati 25g, rhizoma dioscoreae nipponicae 15g, Oldenlandia diffusa 20g, edible tulip 20g, three shuttle 10g, curcuma zedoary 20g, Ramulus euonymi 25g, turtle shell 10g, rheum officinale 15g, scorpio 12g and Qiang Dung beetle worm 10g is made, and the preparation method is the same as that of Example 1.
Embodiment 6
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 20g, radix scrophulariae 20g, Radix Ophiopogonis 15g, campanulaceae 15g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 15g, myrobalan 12g, great burdock achene 15g, plate are blue Root 20g, endothelium corneum gigeriae galli 20g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 10g, dried orange peel 15g, tuber of pinellia 12g, fritillaria thunbergii 15g, radix ranunculi ternati 20g, rhizoma dioscoreae nipponicae 12g, oldenlandia diffusa 15g, edible tulip 15g, three shuttle 20g, curcuma zedoary 10g, Ramulus euonymi 30g, turtle shell 20g, rheum officinale 12g, scorpio 8g It is made with insects 12g, the preparation method is the same as that of Example 1.
Embodiment 7:
A kind of postoperative cracked Chinese medicine of improvement thyroid cancer of the present invention, the Chinese medicine is by poidometer:Radix rehmanniae recen 15g, radix scrophulariae 15g, Radix Ophiopogonis 15g, campanulaceae 6g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 6g, myrobalan 10g, great burdock achene 10g, Radix Isatidis 30g, endothelium corneum gigeriae galli 20g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 20g, dried orange peel 10g, tuber of pinellia 9g, fritillaria thunbergii 20g, radix ranunculi ternati 20g, rhizoma dioscoreae nipponicae 15g are white Flower HERBA HEDYOTIS DIFFUSAE 20g, edible tulip 20g, three shuttle 10g, curcuma zedoary 10g, Ramulus euonymi 20g, turtle shell 10g, rheum officinale 10g, scorpio 10g and dung beetle Worm 20g is made, and the preparation method is the same as that of Example 1.
In said components, wherein:
Radix rehmanniae recen:Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid.Enter ying blood, the deep red polydipsia of tongue, macula hematemesis for heat;Yin asthenia generating intrinsic heat, hectic fever due to yin labor Heat;Injury thirst, Heat Diabetes, dry constipation of intestines.
Radix scrophulariae:Clearing heat and cooling blood, purging fire for removing toxin, enriching yin.It joins the army for warm heresy, invaginate pericardium, febrile virulent maculae;Consumption of YIN caused by febrile disease, Tianjin hinder constipation, hectic fever due to yin labor is coughed;Hot eyes pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Radix Ophiopogonis:Yin nourishing and lung moistening, reinforcing stomach reg fluid, relieving restlessness and restlessness.For syndrome of deficiency of stomach yin;Syndrome of deficiency of lung yin;Syndrome of deficiency of heart yin.
Campanulaceae:Promoting the dispersing function of the lung, eliminating the phlegm, relieving sore-throat, apocenosis.For coughing with a lot of sputum, chest distress;Abscess of throat, aphonia;Pulmonary abscess is spat Purulence.
Radix Glycyrrhizae:It invigorates the spleen and benefits qi, expelling phlegm and arresting coughing, relieving spasm to stop pain is clearing heat and detoxicating, coordinating the drug actions of a prescription.For deficiency of heart-QI, kank Generation, severe palpilation;Syndrome of deficiency of spleen qi;Cough and asthma;Stomach duct and abdomen, four limbs contraction;Pathopyretic ulcer, abscess of throat and drug, food poisoning;It adjusts And pharmacological property.
Fructus Aurantii:Relieving stagnant Qi removes ruffian, resolving sputum disperse accumulation.For gastrointestinal retention, damp-heat dysentery;Thoracic obstruction, accumulation of pathogens in chest;Stagnation of the circulation of vital energy pain in chest and hypochondrium; Postpartum abdominal pain.
Oroxylum indicum:Removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach.For sore throat hoarse voice, cough with lung heat;Stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
Cicada slough:Dispelling wind and heat from the body, relieving sore-throat open sound, promoting eruption, removing nebula, Inflammation Zhijing.For anemopyretic cold, warm disease from the beginning of, Pharyngalgia hoarse voice;Measles without adequate eruption, rubella itch;Cataract;Anxious chronic infantile convulsion, tetanus card.
Myrobalan:Relieving diarrhea with astringents astringes the lung to stop cough, and relieving sore-throat opens sound.For chronic diarrhea, protracted dysentery;Chronic cough, aphonia.
Great burdock achene:Dispelling wind and heat from the body, clearing lung and eliminating the phlegm, relieving sore-throat promoting eruption, removing toxicity for detumescence.For treating anemopyretic cold, warm disease from the beginning of, Measles without adequate eruption, rubella itch, carbuncle sore tumefacting virus, erysipelas, mumps, sore throat.
Radix Isatidis:It is clearing heat and detoxicating, cool blood, relieving sore-throat.For fever caused by exogenous pathogens, warm disease is from the beginning of abscess of throat;Warm disease macular eruption, Zha The cheek, erysipelas, too fat to move sore.
Endothelium corneum gigeriae galli:Food digesting stomach fortifying, arresting seminal emission.For eating accumulation, infantile malnutrition;Emission due to the kidney deficiency, the enuresis;Stranguria dne to urolithiasis Card, gall stone.
Rhizoma Chuanxiong:Blood-activating and qi-promoting, wind-expelling pain-stopping.It is demonstrate,proved for stagnation of QI and blood pain;Headache, rheumatic arthralgia.
Rhizoma Atractylodis Macrocephalae:It replenishes qi to invigorate the spleen, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For syndrome of deficiency of spleen qi;Spontaneous perspiration due to deficiency of vital energy;Spleen deficiency threatened abortion.
Dried orange peel:Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For taste syndrome of qi stagnation;Vomiting, hiccup;Damp phlegm, cold productive cough are coughed;Thoracic obstruction.
The tuber of pinellia:It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;Externally used detumescence analgesic.For damp phlegm, cold-phlegm syndrome;Vomiting;The heart Lower ruffian, accumulation of pathogens in chest, globus hysteriocus;Goiter, subcutaneous nodule, swollen ulcer drug, venomous snake bite.
Fritillaria thunbergii:Clearing heat and eliminating phlegm, dissipating bind disappear carbuncle.For wind-heat, phlegm-heat cough;Scrofula, goiter, acute mastitis sore, pulmonary abscess.
Radix ranunculi ternati:Reducing phlegm and resolving masses, removing toxicity for detumescence.For scrofula subcutaneous nodule;Furunculosis, snakebite and bugbite.
Rhizoma dioscoreae nipponicae:Wind-damp dispelling, promoting blood circulation and removing obstruction in channels, clearing lung and eliminating phlegm.For rheumatism bi Zheng;Phlegm heat panting cough.
Oldenlandia diffusa:Clearing heat and detoxicating, dampness removing is treating stranguria.For carbuncle sore tumefacting virus, abscess of throat, venomous snake bite;Puckery pain of heat gonorrhea.
Edible tulip:It is clearing heat and detoxicating, carbuncle that disappears dissipating bind.For ulcer serious case of furuncle, scrofula subcutaneous nodule;Abdominal mass and lump.
Three shuttles:Breaking blood and promoting the circulation of qi, clearing stagnation and killing pain.Yong Yu lumps in the chest and abdomen, menostasis, trusted subordinate's stasis caused pain;Dyspepsia abdominal distention.
Curcuma zedoary:Breaking blood and promoting the circulation of qi, clearing stagnation and killing pain.Yong Yu lumps in the chest and abdomen, menostasis, trusted subordinate's stasis caused pain;Dyspepsia abdominal distention.
Ramulus euonymi:Blood-breaking, promoting menstruation, desinsection.For menostasis , Disorder lump in the abdomen, postpartum stasis abdominal pain, abdominal pain due to enterositosis.
Turtle shell:Nourishing and suppressing Yang is brought down a fever except steaming, resolving hard lump.For syndrome of yin deficiency of liver and kidney;Lumps in the chest and abdomen.
Rheum officinale:Heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow.For:Stagnant constipation;Blood-head tells nosebleed, hot eyes Pharynx swelling;Pathopyretic ulcer, burn and scald;Blood stasis symptom;Damp-heat dysentery, jaundice, stranguria.
Scorpio:Relieve the wind syndrome antispastic, dispersing pathogen accumulation are removed obstruction in channels to relieve pain.It twitches for spasm;Sore swollen toxin, scrofula tuberculosis;Rheumatism is stupid Numbness;Intractable migraine and general headache.
Insects:Po Disorder knot leads to two just, epilepsy of calming the frightened, and removing toxic substances and promoting tissue regeneration dissipates swollen hemostasis.For solidity constipation;Rheumatism numbness Bitterly, cancerous swelling heavily fortified point block, it is red from diarrhea.
Above-mentioned component science, reasonable compatibility, are supported mutually, have the promoting flow of qi and blood circulation, resolving sputum open sound relieving sore-throat, pleasant dredging collateral and The effect of clearing heat and detoxicating, effective for improving the postoperative hoarseness of thyroid cancer, good effect, drug safety is to improve thyroid gland Innovation on the postoperative hoarseness drug of cancer, and obtained sufficiently proving through clinical data, related clinical data is as follows:
(One), case selection standard:
Hoarseness mostly in the postoperative appearance of thyroid cancer, shows as hoarseness, has a low and deep voice, is coarse hoarse, and speech is laborious, gulps down Pain is swallowed, notably sound is difficult to issue, approximation whisper in sb.'s ear;Vocal cord examination is shown in:Vocal cords are red, it is seen that part blood vessel dilatation, vocal cords are in dark Red, congested plump oedema.It is all that there is above-mentioned symptom sign person, the alternatively standard of case, and give Chinese medicine of the present invention and control It treats.
(Two), diagnostic criteria
A, all with above-mentioned(One)The symptom, it is preoperative to be made a definite diagnosis through B ultrasound, thyroid gland radioisotope scanning or needle biopsy, And Postoperative pathological confirmation is diagnosed as thyroid cancer and is selected;With or without abnormal thyroid function.
B, case exclusion criteria:Gestation, breast feeding women, dysfunction of liver person;It is associated with angiocarpy, liver, kidney and hematopoiesis The severe primaries disease such as system, mental patient;Receive other Chinese medicines, glucocorticoid and other immunosuppressant treatments Person;Other drugs clinical test person is participated in nearly March.
(Three), efficacy assessment standard:
Comprehensive therapeutic effect criterion:Calculation formula:(Pre-treatment score-post treatment integral)/ pre-treatment score, with percentage table Show.Recovery from illness:Symptom and sign disappears substantially, and integral is greater than or equal to 95%;It is effective:Symptom and sign is obviously improved, and integral integral is greater than Or it is equal to 75%;Effectively:Symptom and sign take a favorable turn, and integral is greater than or equal to 50%;In vain:Symptom and sign is not improved, even It aggravates, integrates less than 50%.
(Four), therapeutic scheme:
It to being diagnosed as the postoperative patient of thyroid cancer, and with hoarseness symptom, is treated, is taken with Chinese medicine of the invention Used time, once in the morning and once at night, each 100-150ml, two hours cool clothes after meal, 7 days as a course for the treatment of, counts curative effect after 4 courses for the treatment of.
(Five), statistical procedures:
Selected patient totally 77, wherein male 25, female 52, the age be (26.7 ± 14.3) year.By above-mentioned(Four)Therapeutic scheme, The Chinese medicine that the oral present invention provides counts after 4 courses for the treatment of, clinical recovery 16, it is 25 effective, 27 effective, invalid 9, always have Efficiency shows that the invention Chinese medicine treats the postoperative hoarseness symptom significant effect of thyroid cancer, has reached clinical treatment up to 89.3% Purpose, and over the course for the treatment of, have no obvious adverse reaction.
(Six), typical case
For more detailed description treatment condition, the curative effect situation of typical case and treatment is given below:
Case 1:Liu, male, 29 years old, occurs roughing rough for thyroid cancer postoperative 2 days, and speech is laborious.Vocal cord examination is shown in:Sound With red, it is seen that see part blood vessel dilatation.After taking 1 course for the treatment of of Chinese medicine, patient's above-mentioned symptom gradually mitigates.Continue to take in this After 2 courses for the treatment of of medicine, symptom and sign disappears substantially.
Case 2:Rice certain, female, 20 years old, thyroid cancer gradually appeared pharyngeal pain postoperative January, and sound is difficult to issue.Vocal cords Inspection is shown in:Vocal cords are dark red, congested.After taking 1 course for the treatment of of Chinese medicine, patient's above-mentioned symptom gradually mitigates.Continue to take Chinese medicine 3 After a course for the treatment of, symptom and sign disappears substantially.
Case 3:Slowly certain, female 39 years old, gradually appears hoarseness, droning for thyroid cancer postoperative 7 days.Vocal cord examination is shown in:Sound With micro- red.It is oral from Chinese Traditional Medicines are taken, it is specifically unknown, in vain.After taking 3 courses for the treatment of of Chinese medicine, patient's above-mentioned symptom gradually subtracts Gently.Continue after taking 5 courses for the treatment of of Chinese medicine, symptom and sign disappears substantially.
Case 4:It is peaceful certain, female, 49 years old, thyroid cancer, which gradually appears postoperative March, showed as that speech is laborious, swallows pain, sound Sound is difficult to issue, approximation whisper in sb.'s ear;Vocal cord examination is shown in:Vocal cords are in dark red, congested plump oedema.It is western medicine about two weeks, clinical Symptom is mitigated.After change and take 4 courses for the treatment of of this prescription after, clinical symptoms disappear.Patient's recovery from illness.
Case 5:Zhang, male, 21 years old, student enrollment gradually appeared and shows as sound for thyroid papillary carcinoma postoperative 1 year It is hoarse, it is droning;Vocal cord examination is shown in:Vocal cords are red, it is seen that part blood vessel dilatation.After taking 1 course for the treatment of of Chinese medicine, patient's above-mentioned symptom Gradually mitigate.Continue after taking 5 courses for the treatment of of Chinese medicine, symptom and sign disappears substantially.
Case 6:Mr. Wang, female 34 years old, previously there is hyperlipidemia medical history.Thyroid papillary carcinoma gradually appears table postoperative June It is now hoarseness, has sore throat;Vocal cord examination is shown in:Vocal cords are red, it is seen that part blood vessel dilatation, vocal cords slightly oedema.Hospitalization About 10 days, clinical symptoms were alleviated.After 8 courses for the treatment of of this prescription are taken in discharge, clinical symptoms are substantially reduced.
(Seven), conclusion
The present invention and combines the principle of prolonged illness impairment of yin according to the principle of activating microcirculation and removing stasis medicinal, eleminating phlegm and freeing channels, and with promoting blood circulation, Apophlegmatisant dispels It based on heresy, supplemented by enriching yin boost qi drug, is finally reached relieving sore-throat and opens the benefits of silent, there is unique curative effect at noon of the invention to this disease, can It is the active drug for improving the postoperative hoarseness symptom of thyroid cancer to be relieved symptom, it is efficient up to 88% or more, It has no toxic side effect, curative effect is stablized, and securely and reliably, clinical meaning is huge.

Claims (8)

1. a kind of postoperative cracked Chinese medicine of improvement thyroid cancer, which is characterized in that the Chinese medicine is by poidometer:Radix rehmanniae recen 10-20g, radix scrophulariae 10-20g, Radix Ophiopogonis 10-20g, campanulaceae 6-15g, Radix Glycyrrhizae 6-15g, Fructus Aurantii 10-20g, Oroxylum indicum 10-20g, cicada slough 6-15g, myrobalan 10-20g, great burdock achene 10-20g, Radix Isatidis 20-30g, endothelium corneum gigeriae galli 20-30g, Rhizoma Chuanxiong 10-20g, Rhizoma Atractylodis Macrocephalae 10- 20g, dried orange peel 10-20g, tuber of pinellia 9-15g, fritillaria 10-20g, radix ranunculi ternati 20-30g, rhizoma dioscoreae nipponicae 10-20g, oldenlandia diffusa 15- 25g, edible tulip 15-25g, three shuttle 10-20g, curcuma zedoary 10-20g, Ramulus euonymi 15-30g, turtle shell 10-20g, rheum officinale 6-20g, scorpio 6-15g and insects 10-20g are made, wherein mix above-mentioned Chinese medicine, add the water of 6-8 times of Chinese medicine weight, impregnate half Hour, it boils by intense fire, uses instead and be cooked by slow fire 30 minutes, filter, obtain the first filtrate, filter residue adds the water of 6-8 times of Chinese medicine weight, intense fire It boils, uses instead and be cooked by slow fire 30 minutes, filter, obtain the second filtrate, filtrate will be uniformly mixed twice, and be concentrated into 200-300ml.
2. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 13-17g, radix scrophulariae 13-17g, Radix Ophiopogonis 12-18g, campanulaceae 8-13g, Radix Glycyrrhizae 8-13g, Fructus Aurantii 13-17g, the wooden butterfly Butterfly 13-17g, cicada slough 8-13g, myrobalan 13-17g, great burdock achene 13-17g, Radix Isatidis 23-27g, endothelium corneum gigeriae galli 23-27g, Rhizoma Chuanxiong 13- 17g, Rhizoma Atractylodis Macrocephalae 13-17g, dried orange peel 13-17g, tuber of pinellia 11-13g, fritillaria 13-17g, radix ranunculi ternati 22-28g, rhizoma dioscoreae nipponicae 13-17g are white Flower HERBA HEDYOTIS DIFFUSAE 18-22g, edible tulip 18-22g, three shuttle 13-17g, curcuma zedoary 13-17g, Ramulus euonymi 18-27g, turtle shell 13-17g, greatly Yellow 9-17g, scorpio 8-13g and insects 13-17g are made.
3. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 15g, radix scrophulariae 15g, Radix Ophiopogonis 15g, campanulaceae 6g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 6g, myrobalan 10g, great burdock achene 10g, Radix Isatidis 30g, endothelium corneum gigeriae galli 20g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 20g, dried orange peel 10g, tuber of pinellia 9g, fritillaria 20g, ram's horn Careless 20g, rhizoma dioscoreae nipponicae 15g, oldenlandia diffusa 20g, edible tulip 20g, three shuttle 10g, curcuma zedoary 10g, Ramulus euonymi 20g, turtle shell 10g, greatly Yellow 10g, scorpio 10g, insects 20g are made.
4. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 12g, radix scrophulariae 12g, Radix Ophiopogonis 12g, campanulaceae 10g, Radix Glycyrrhizae 6g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 10g are scolded Sub- 15g, great burdock achene 15g, Radix Isatidis 20g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 10g, dried orange peel 15g, tuber of pinellia 10g, fritillaria 15g, Radix ranunculi ternati 30g, rhizoma dioscoreae nipponicae 20g, oldenlandia diffusa 25g, edible tulip 25g, three shuttle 12g, curcuma zedoary 12g, Ramulus euonymi 30g, turtle shell 12g, rheum officinale 6g, scorpio 6g, insects 20g are made.
5. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 15g, radix scrophulariae 12g, Radix Ophiopogonis 12g, campanulaceae 8g, Radix Glycyrrhizae 12g, Fructus Aurantii 12g, Oroxylum indicum 15g, cicada slough 8g, myrobalan 12g, great burdock achene 12g, Radix Isatidis 25g, endothelium corneum gigeriae galli 30g, Rhizoma Chuanxiong 15g, Rhizoma Atractylodis Macrocephalae 15g, dried orange peel 12g, tuber of pinellia 12g, fritillaria 12g, cat Pawl grass 20g, rhizoma dioscoreae nipponicae 15g, oldenlandia diffusa 18g, edible tulip 18g, three shuttle 15g, curcuma zedoary 15g, Ramulus euonymi 25g, turtle shell 15g, Rheum officinale 10g, scorpio 8g, insects 20g are made.
6. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 18, radix scrophulariae 18g, Radix Ophiopogonis 15g, campanulaceae 12g, Radix Glycyrrhizae 15g, Fructus Aurantii 20g, Oroxylum indicum 12, cicada slough 12g, myrobalan 10g, great burdock achene 10g, Radix Isatidis 20g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 12g, Rhizoma Atractylodis Macrocephalae 12g, dried orange peel 12g, tuber of pinellia 10g, fritillaria 15g, cat Pawl grass 25g, rhizoma dioscoreae nipponicae 15g, oldenlandia diffusa 20g, edible tulip 20g, three shuttle 10g, curcuma zedoary 20g, Ramulus euonymi 25g, turtle shell 10g, Rheum officinale 15g, scorpio 12g, insects 10g are made.
7. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 20g, radix scrophulariae 20g, Radix Ophiopogonis 15g, campanulaceae 15g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 20g, cicada slough 15g are scolded Sub- 12g, great burdock achene 15g, Radix Isatidis 20g, endothelium corneum gigeriae galli 20g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae 10g, dried orange peel 15g, tuber of pinellia 12g, fritillaria 15g, Radix ranunculi ternati 20g, rhizoma dioscoreae nipponicae 12g, oldenlandia diffusa 15g, edible tulip 15g, three shuttle 20g, curcuma zedoary 10g, Ramulus euonymi 30g, turtle shell 20g, rheum officinale 12g, scorpio 8g, insects 12g are made.
8. the postoperative cracked Chinese medicine of improvement thyroid cancer according to claim 1, which is characterized in that the Chinese medicine is by weight Meter:Radix rehmanniae recen 15g, radix scrophulariae 15g, Radix Ophiopogonis 15g, campanulaceae 11g, Radix Glycyrrhizae 10g, Fructus Aurantii 15g, Oroxylum indicum 15g, cicada slough 11g are scolded Sub- 15g, great burdock achene 15g, Radix Isatidis 25g, endothelium corneum gigeriae galli 25g, Rhizoma Chuanxiong 15g, Rhizoma Atractylodis Macrocephalae 15g, dried orange peel 15g, tuber of pinellia 12g, fritillaria 15g, Radix ranunculi ternati 25g, rhizoma dioscoreae nipponicae 15g, oldenlandia diffusa 20g, edible tulip 20g, three shuttle 15g, curcuma zedoary 15g, Ramulus euonymi 22g, turtle shell 15g, rheum officinale 13g, scorpio 11g and insects 15g are made.
CN201810992386.7A 2018-08-29 2018-08-29 A kind of postoperative cracked Chinese medicine of improvement thyroid cancer Pending CN108815470A (en)

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Application publication date: 20181116