CN108794497A - A kind of new N- benzyls acridone type alkaloid and preparation method thereof and purposes - Google Patents
A kind of new N- benzyls acridone type alkaloid and preparation method thereof and purposes Download PDFInfo
- Publication number
- CN108794497A CN108794497A CN201810743707.XA CN201810743707A CN108794497A CN 108794497 A CN108794497 A CN 108794497A CN 201810743707 A CN201810743707 A CN 201810743707A CN 108794497 A CN108794497 A CN 108794497A
- Authority
- CN
- China
- Prior art keywords
- fractions
- benzyls
- type alkaloid
- preparation
- thick paste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC(C)(C=Cc1c(c2c3OC)N(Cc(cc4)ccc4O)c(cc4OC(C(*)(CO)CO)Oc4c4)c4C2=O)Oc1c3OC Chemical compound CC(C)(C=Cc1c(c2c3OC)N(Cc(cc4)ccc4O)c(cc4OC(C(*)(CO)CO)Oc4c4)c4C2=O)Oc1c3OC 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/153—Ortho-condensed systems the condensed system containing two rings with oxygen as ring hetero atom and one ring with nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Compound | Phagocytic rate |
Chloroform thick paste | 1.96±0.09 |
B fractions | 1.75±0.11 |
Chemical compounds I | 1.51±0.04 |
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810743707.XA CN108794497B (en) | 2018-07-09 | 2018-07-09 | Novel N-benzyl acridone alkaloid and preparation method and application thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810743707.XA CN108794497B (en) | 2018-07-09 | 2018-07-09 | Novel N-benzyl acridone alkaloid and preparation method and application thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108794497A true CN108794497A (en) | 2018-11-13 |
CN108794497B CN108794497B (en) | 2020-09-22 |
Family
ID=64075594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810743707.XA Active CN108794497B (en) | 2018-07-09 | 2018-07-09 | Novel N-benzyl acridone alkaloid and preparation method and application thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108794497B (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS203756B1 (en) * | 1979-04-06 | 1981-03-31 | Bohumil Proksa | Tetracyclic compounds derived from narceonic acid and process for preparing thereof |
CN104610271A (en) * | 2015-01-09 | 2015-05-13 | 新乡学院 | 12-(2-fluorophenyl)-benzo [h][1,3] methylenedioxy [4,5-b] acridine-10,11-diketone and synthesis method thereof |
-
2018
- 2018-07-09 CN CN201810743707.XA patent/CN108794497B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS203756B1 (en) * | 1979-04-06 | 1981-03-31 | Bohumil Proksa | Tetracyclic compounds derived from narceonic acid and process for preparing thereof |
CN104610271A (en) * | 2015-01-09 | 2015-05-13 | 新乡学院 | 12-(2-fluorophenyl)-benzo [h][1,3] methylenedioxy [4,5-b] acridine-10,11-diketone and synthesis method thereof |
Non-Patent Citations (2)
Title |
---|
MARK R. SPALLER,等: "Combinatorial Synthetic Design. Solution and Polymer-Supported Synthesis of Heterocycles via Intramolecular Aza Diels-Alder and Imino Alcohol Cyclizations", 《J. COMB. CHEM.》 * |
周杨晶,等: "民族药木耳菜挥发油成分和脂溶性成分GC-MS分析", 《天然产物研究与开发》 * |
Also Published As
Publication number | Publication date |
---|---|
CN108794497B (en) | 2020-09-22 |
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GR01 | Patent grant | ||
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TR01 | Transfer of patent right |
Effective date of registration: 20201230 Address after: No.1, Zhangjiagang East Road, Yitang Town, Pizhou City, Xuzhou City, Jiangsu Province Patentee after: Pizhou Binhe SME Management Service Co.,Ltd. Address before: No.716, 7th floor, building 4, No.99 Guangfu Road, Wuhou District, Chengdu, Sichuan 610000 Patentee before: Chengdu yishenrui Technology Co.,Ltd. Effective date of registration: 20201230 Address after: No.716, 7th floor, building 4, No.99 Guangfu Road, Wuhou District, Chengdu, Sichuan 610000 Patentee after: Chengdu yishenrui Technology Co.,Ltd. Address before: 330004 No. 818 Xingwan Avenue, Wanli District, Nanchang City, Jiangxi Province Patentee before: JIANGXI University OF TRADITIONAL CHINESE MEDICINE |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210820 Address after: 610000 Group 8, zhuanlong Town, Jintang County, Chengdu City, Sichuan Province Patentee after: Li Xiaojing Address before: No.1, Zhangjiagang East Road, Yitang Town, Pizhou City, Xuzhou City, Jiangsu Province Patentee before: Pizhou Binhe SME Management Service Co.,Ltd. |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20211011 Address after: 510000 room 2501, No. 163, Huangpu Avenue West, Tianhe District, Guangzhou City, Guangdong Province (Part I) (office only) Patentee after: CHINESE FOOD ANHONG (GUANGDONG) HEALTH INDUSTRY Co.,Ltd. Address before: 610000 Group 8, zhuanlong Town, Jintang County, Chengdu City, Sichuan Province Patentee before: Li Xiaojing |
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TR01 | Transfer of patent right |