CN108739634A - Device for testing animal to gas tolerance - Google Patents

Device for testing animal to gas tolerance Download PDF

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Publication number
CN108739634A
CN108739634A CN201810407573.4A CN201810407573A CN108739634A CN 108739634 A CN108739634 A CN 108739634A CN 201810407573 A CN201810407573 A CN 201810407573A CN 108739634 A CN108739634 A CN 108739634A
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CN
China
Prior art keywords
animal
gas
chamber
fan
tolerance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810407573.4A
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Chinese (zh)
Inventor
邓超
柳海
孙翼
朱在满
柴琳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wannan Medical College
Original Assignee
Wannan Medical College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wannan Medical College filed Critical Wannan Medical College
Priority to CN201810407573.4A priority Critical patent/CN108739634A/en
Publication of CN108739634A publication Critical patent/CN108739634A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/02Breeding vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/0047Air-conditioning, e.g. ventilation, of animal housings
    • A01K1/0052Arrangement of fans or blowers
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals

Abstract

Present invention is disclosed a kind of devices for testing animal to gas tolerance, device includes the air chamber and animal chamber with baffle interval, the partition board is equipped with the ventilation opening of connection air chamber and animal chamber, the animal intracavitary is fixed with support plate by elastic support structure, the support plate bottom surface is fixed at least one shock sensor, it is placed with gas generator in the air chamber, the gas generator is combined by least three gas generating units and is constituted, each gas generating unit is equipped with storage chamber, the storage chamber bottom is equipped with heated base, the storage chamber open top is simultaneously equipped with turnover panel, the turnover panel opens or closes storage chamber by the driving of independent electrical control mechanism.The present invention can automatic test animal to the tolerance of gas, and stable and reliable in work, high degree of automation simplifies the experiment to gas detection using animal.

Description

Device for testing animal to gas tolerance
Technical field
The present invention relates to test the device of detection device more particularly to animal to gas tolerance.
Background technology
Animal is very sensitive to gas, therefore is usually tested gas using animal (such as mouse) in laboratory, surveys The gas of examination includes poison gas, inducing gas, excited gas etc., by detecting animal to these other tolerances, needed for acquisition The parameter wanted, however at present not there are one dedicated test device, can not precisely, reliable, automation acquisition animal is to gas The tolerance of body.
Invention content
The technical problem to be solved by the present invention is to realize that a kind of accurate, reliable, automation acquisition animal is resistance to gas By the device of ability.
To achieve the goals above, the technical solution adopted by the present invention is:For testing animal to gas tolerance Device, device include the air chamber and animal chamber with baffle interval, and the partition board is equipped with the logical of connection air chamber and animal chamber Air port, the animal intracavitary are fixed with support plate by elastic support structure, and the support plate bottom surface is fixed at least one shake Sensor is moved, is placed with gas generator in the air chamber, the gas generator is by least three gas generating unit groups It closes and constitutes, each gas generating unit is equipped with storage chamber, and the storage chamber bottom is equipped with heated base, the storage chamber top Portion is open and is equipped with turnover panel, and the turnover panel opens or closes storage chamber by the driving of independent electrical control mechanism.
The gas generating unit is fixed in air chamber side by side, is placed in the storage chamber and has been adsorbed pre- evaporating solution Test paper.
There are two the ventilation opening is set, and it is separately installed with the first fan and the second fan, first fan is by animal Chamber is dried to air chamber, and second fan is dried from air chamber to animal chamber, and the first fan blowing direction is towards gas Generator.
The animal intracavitary is equipped with gas concentration sensor, and the animal chamber is connected to blast pipe and discharge pipe respectively, institute It states and is equipped with electrically operated valve in blast pipe and discharge pipe, the blast pipe is connect with scavenger fan.
The mouth that picks and places for being placed and taken out animal is equipped with above the animal chamber, and for sealing the cabin for picking and placeing mouth Door, the animal chamber is transparent cavity, and is equipped with camera outside animal chamber.
The animal intracavitary is equipped with the temperature controller for keeping animal cavity temperature constant, and the temperature controller includes heater Structure, refrigeration mechanism and temperature sensor.
Device is equipped with controller, and the controller is connected with storage device, display equipment and input equipment, and the vibrations pass Sensor exports inductive signal to controller, and the camera exports video information to controller, the controller output driving letter Number to temperature controller, the first fan, the second fan, gas generator.
Based on the control method for testing animal to the device of gas tolerance:
After step 1, device start, the first fan and the second fan are opened, records shock sensor information in real time;
Step 2, the turnover panel for opening the gas generating unit that a turnover panel is closed, and start the gas and list occurs The heated base of member continues setting time;
Step 3, the return to step 2 if having the gas generating unit for not opening turnover panel, if all gas generating unit turns over Plate is opened, and next step is executed;
Step 4, test terminate.
The step 1 signal that record gas concentration sensor is acquired in fact, in step 2 implementation procedure, if vibrations The vibration amplitude or frequency of sensor acquisition are more than setting upper limit value, then follow the steps 5;
Step 5 opens electrically operated valve, and starts scavenger fan and take a breath for animal chamber, when the vibrations of shock sensor acquisition Amplitude or frequency are less than preset lower limit, then test terminates, and record vibration amplitude or frequency is changed to setting by setting upper limit value In the lower limiting value time, gas concentration interval value that gas concentration sensor is acquired.
The image information of the real-time recording camera acquisition of step 1.
The step 1 driving temperature controller makes animal cavity temperature reach set temperature.
The present invention can automatic test animal at different ambient temperatures to the tolerance of specific gas, also may be used certainly To allow animal to take some drugs, the front and back animal of test medication can try the tolerance of specific gas indirectly by gas It tests and drug is tested, have a wide range of application, and entire stable and reliable in work, high degree of automation, reduce experiment difficulty And human input.
Description of the drawings
The content of every width attached drawing expression in description of the invention and the label in figure are briefly described below:
Fig. 1 is for testing device vertical view of the animal to gas tolerance;
Fig. 2 is for testing device side view of the animal to gas tolerance;
Fig. 3 is the one of cellular construction schematic diagram of gas generator in Fig. 1,2;
Label in above-mentioned figure is:1, air chamber;2, animal chamber;3, support plate;4, shock sensor;5, the first wind Fan;6, the second fan;7, gas generator;71, storage chamber;72, heated base;73, turnover panel;74, test paper;8, blast pipe;9, Discharge pipe;10 electrically operated valves;11, scavenger fan.
Specific implementation mode
Device is set there are two the cavity sealed, i.e. animal chamber 2 and air chamber 1, and partition board is used between air chamber 1 and animal chamber 2 Interval, partition board are equipped with the ventilation opening of connection air chamber 1 and animal chamber 2, clean and pick and place for convenience object (animal), gas Chamber 1 and animal chamber 2, which are equipped with, picks and places mouth, and for sealing the hatch door for picking and placeing mouth, to ensure leakproofness, hatch door and picks and places between mouth Equipped with sealing strip.
Animal chamber 2 is for placing toy, and when test can be put into more toys simultaneously, and 2 bottom level of animal chamber is solid Surely there is a support plate 3,3 bottom surface quadrangle of support plate is fixed on 2 bottom surface of animal chamber by elastic support structure, and elastic support structure can be with Using the structure of the specific elasticity such as spring, rubber column, so that animal can drive branch when walking is run in support plate 3 Fagging 3 shakes, and in order to acquire this vibration signal, at least one shock sensor 4 is fixed in 3 bottom surface of support plate.
Gas generator 7 is placed in air chamber 1, gas generator 7 is combined by least three gas generating units and is constituted, The structure of each gas generating unit is identical, and multiple gas generating units constitute gas generator 7 after fixing side by side, and gas occurs Device 7 is fixed on the bottom surface of air chamber 1.Each gas generating unit is equipped with storage chamber 71, be placed in storage chamber 71 adsorbed it is pre- The test paper 74 of evaporating solution, 71 bottom of storage chamber is equipped with heated base 72, electric heating wire is disposed in heated base 72, by logical Electricity is heated, and accelerates the volatilization of liquid on test paper 74,71 open top of storage chamber to be simultaneously equipped with turnover panel 73, turnover panel 73 is for controlling The volatilization opportunity of each gas generating unit, turnover panel 73 open or close storage chamber 71 by the driving of independent electrical control mechanism, specifically For, turnover panel 73 is hinged on the upper eaves in 71 top of storage chamber by shaft, and shaft and turnover panel 73 are affixed, and shaft one end is affixed with teeth Wheel, is engaged by the driving gear on a small machine with the gear in shaft, realizes the control overturn to turnover panel 73.
It is preferred that there are two ventilation opening sets, one is air inlet, and one is air outlet so that animal chamber 2 and air chamber 1 are constituted One internal circulation system, two ventilation openings are separately installed with the first fan 5 and the second fan 6, the first fan 5 from animal chamber 2 to Air chamber 1 is dried, and second fan 6 is dried from air chamber 1 to animal chamber 2.In order to ensure the volatilization effect of gas generator 7 Fruit, 5 blowing direction of the first fan is towards gas generator 7 so that and the gas evaporated is dispersed into air faster, and Under the action of two fans, it is recycled to animal chamber 2.
For reaction of the more detailed record animal under the effect of various concentration gas, animal chamber 2 is transparent cavity, and Camera is installed outside animal chamber 2, while in order to ensure the constant of experimental situation, and experimental enviroment temperature can be adjusted as needed Degree is equipped in animal chamber 2 for making the temperature controller that temperature is constant in animal chamber 2, temperature controller include heating mechanism, refrigeration mechanism and Temperature sensor.
The gas concentration when moment most sensitive to gas in order to facilitate record toy, gas is equipped in animal chamber 2 Concentration sensor, the sensor change according to the gaseous species specifically tested, if influence of the test chlorine gas concentration to animal, Chlorine gas concentration sensor is installed.
In order to facilitate experiment, animal chamber 2 is also connected to external environment by blast pipe 8 with discharge pipe 8 respectively, in blast pipe 8 Be mounted on electrically operated valve 10 in discharge pipe 8, ensure the leakproofness when experiment of animal chamber, 8 end of blast pipe connection ventilation wind Fan, for animal intracavitary air blast, taking a breath.
Device is equipped with controller, and controller is connected with storage device, display equipment and input equipment, PC machine may be used, Gas concentration sensor and shock sensor 4 export inductive signal to controller, and camera exports video information to controller, control Device output drive signal processed is to temperature controller, the first fan 5, the second fan 6, gas generator 7, electrically operated valve 10 and scavenger fan 11, the automatic operating of realization device.
Based on the above-mentioned control method for testing animal to the device of gas tolerance:
After step 1, device start, the first fan 5 and the second fan 6 are opened, records 4 information of shock sensor in real time, together When can also open camera and recorded in real time, if temperature needs to adjust, drive temperature controller that temperature in animal chamber 2 is made to reach Set temperature;
Step 2,73 original state of each turnover panel of gas generating unit are horizontally disposed, and storage chamber 71 is made to be in seal shape State at this point, opening the turnover panel 73 for the gas generating unit that one of turnover panel 73 is closed, and starts gas generation The heated base 72 of unit continues setting time (such as 1 minute), and holding 73 open state of turnover panel, can select after the time reaches The heated base 72 for closing the gas generating unit can also select that the heated base 72 is kept to be in heated condition, according to need It designs;
Step 3, the return to step 2 if having the gas generating unit for not opening turnover panel 73, increase volatilization gas concentration, if The turnover panel 73 of all gas generating unit opens (or having had been switched on the gas generating unit turnover panel 73 of setting quantity) then Execute next step;
Step 4, test terminate.User can transfer test data as needed later.
Above-mentioned experiment needs manual analysis data, checks that experiment process, the degree of automation are low.
It is maximum to the image of animal in order to accurately obtain some section gas concentration automatically, it was executed in step 2 Cheng Zhong, if vibration amplitude or frequency that shock sensor 4 acquires are more than setting upper limit value, animal starts restless at this time, then executes Step 5;
Step 5 opens electrically operated valve 10, and starts scavenger fan 11 and take a breath for animal chamber, when shock sensor acquisition Vibration amplitude or frequency are less than preset lower limit (setting upper limit value is more than preset lower limit), and animal restarts peace and quiet at this time, The air of animal intracavitary, test can be used to terminate, vibration amplitude is recorded or frequency is changed to setting lower limit by setting upper limit value It is worth in the time, the gas concentration interval value that gas concentration sensor is acquired, this interval value is that animal abnormal response occurs Section, every time experiment can place more toys in animal chamber 2, and by test of many times, can get more Accurate gas concentration interval value, such test method, high degree of automation, and there is higher referential.
The present invention is exemplarily described above in conjunction with attached drawing, it is clear that the present invention implements not by aforesaid way Limitation, as long as the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress is used, or without changing Other occasions are directly applied to by the design of the present invention and technical solution, within protection scope of the present invention.

Claims (10)

1. the device for testing animal to gas tolerance, it is characterised in that:Device includes the air chamber with baffle interval With animal chamber, the partition board is equipped with the ventilation opening of connection air chamber and animal chamber, and the animal intracavitary is tied by flexibly supporting Structure is fixed with support plate, and the support plate bottom surface is fixed at least one shock sensor, gas is placed in the air chamber Generator, the gas generator are combined by least three gas generating units and are constituted, and each gas generating unit is equipped with Storage chamber, the storage chamber bottom are equipped with heated base, and the storage chamber open top is simultaneously equipped with turnover panel, and the turnover panel is by independence Electrical control mechanism driving open or close storage chamber.
2. the device according to claim 1 for testing animal to gas tolerance, it is characterised in that:The gas Generating unit is fixed in air chamber side by side, and the test paper for having adsorbed pre- evaporating solution is placed in the storage chamber.
3. the device according to claim 2 for testing animal to gas tolerance, it is characterised in that:The ventilation There are two mouth is set, and it is separately installed with the first fan and the second fan, first fan is dried from animal chamber to air chamber, institute It states the second fan to be dried from air chamber to animal chamber, the first fan blowing direction is towards gas generator.
4. the device according to claim 1 or 3 for testing animal to gas tolerance, it is characterised in that:It is described Animal intracavitary is equipped with gas concentration sensor, and the animal chamber be connected to blast pipe and discharge pipe respectively, the blast pipe with go out Electrically operated valve is equipped in air hose, the blast pipe is connect with scavenger fan.
5. the device according to claim 4 for testing animal to gas tolerance, it is characterised in that:The animal The mouth that picks and places for being placed and taken out animal is equipped with above chamber, and for sealing the hatch door for picking and placeing mouth, the animal chamber is Bright cavity, and camera is installed outside animal chamber.
6. the device according to claim 5 for testing animal to gas tolerance, it is characterised in that:The animal Intracavitary is equipped with the temperature controller for keeping animal cavity temperature constant, and the temperature controller includes heating mechanism, refrigeration mechanism and temperature Sensor.
7. the device according to claim 6 for testing animal to gas tolerance, it is characterised in that:Device is equipped with Controller, the controller are connected with storage device, display equipment and input equipment, and the gas concentration sensor and vibrations pass Sensor exports inductive signal to controller, and the camera exports video information to controller, the controller output driving letter Number to temperature controller, the first fan, the second fan, gas generator, scavenger fan and electrically operated valve.
8. based on the control method for testing animal to the device of gas tolerance described in claim 1-7, feature exists In:
After step 1, device start, the first fan and the second fan are opened, records shock sensor information in real time;
Step 2, the turnover panel for opening the gas generating unit that a turnover panel is closed, and start the gas generating unit Heated base continues setting time;
Step 3, the return to step 2 if having the gas generating unit for not opening turnover panel, if the turnover panel of all gas generating unit is equal Unlatching then executes next step;
Step 4, test terminate.
9. control method according to claim 8, it is characterised in that:The step 1 records gas concentration sensor institute in fact The signal of acquisition, in step 2 implementation procedure, if the vibration amplitude or frequency of shock sensor acquisition are more than the setting upper limit Value, thens follow the steps 5;
Step 5 opens electrically operated valve, and starts scavenger fan and take a breath for animal chamber, when the vibration amplitude of shock sensor acquisition Or frequency is less than preset lower limit, then test terminates, and records vibration amplitude or frequency is changed to setting lower limit by setting upper limit value It is worth in the time, the gas concentration interval value that gas concentration sensor is acquired.
10. control method according to claim 8 or claim 9, it is characterised in that:The real-time recording camera acquisition of step 1 Image information, and drive temperature controller that animal cavity temperature is made to reach set temperature.
CN201810407573.4A 2018-05-02 2018-05-02 Device for testing animal to gas tolerance Pending CN108739634A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810407573.4A CN108739634A (en) 2018-05-02 2018-05-02 Device for testing animal to gas tolerance

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Application Number Priority Date Filing Date Title
CN201810407573.4A CN108739634A (en) 2018-05-02 2018-05-02 Device for testing animal to gas tolerance

Publications (1)

Publication Number Publication Date
CN108739634A true CN108739634A (en) 2018-11-06

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201064488Y (en) * 2007-06-29 2008-05-28 中山大学 Static animal toxicity contaminated cabinet
US20120260574A1 (en) * 2011-04-14 2012-10-18 Lin Jung-Hsin Apparatus for controlling growth of organisms
CN102805039A (en) * 2012-08-15 2012-12-05 山东绿都生物科技有限公司 Miniature animal experiment phytotron and control method
CN202722235U (en) * 2012-07-21 2013-02-13 深圳市华测检测技术股份有限公司 Instrument for testing olfactory sensitivity of animal
CN203988480U (en) * 2014-05-22 2014-12-10 北京慧荣和科技有限公司 Animal gas exposure cabinet
CN204116310U (en) * 2014-09-19 2015-01-21 上海交通大学 The controllable ration being applied to large mouse smells the device inhaling volatile small molecule compound
CN105070173A (en) * 2015-07-16 2015-11-18 沈阳师范大学 Animal direct exposure indoor simulation method in low-temperature rain and snow freezing duration
CN205459178U (en) * 2016-03-20 2016-08-17 金红旭 Novel experiment of animal blast injury device
CN206725539U (en) * 2017-05-27 2017-12-08 沈阳医学院 A kind of experimental animal behavioral data collection, smell warning device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201064488Y (en) * 2007-06-29 2008-05-28 中山大学 Static animal toxicity contaminated cabinet
US20120260574A1 (en) * 2011-04-14 2012-10-18 Lin Jung-Hsin Apparatus for controlling growth of organisms
CN202722235U (en) * 2012-07-21 2013-02-13 深圳市华测检测技术股份有限公司 Instrument for testing olfactory sensitivity of animal
CN102805039A (en) * 2012-08-15 2012-12-05 山东绿都生物科技有限公司 Miniature animal experiment phytotron and control method
CN203988480U (en) * 2014-05-22 2014-12-10 北京慧荣和科技有限公司 Animal gas exposure cabinet
CN204116310U (en) * 2014-09-19 2015-01-21 上海交通大学 The controllable ration being applied to large mouse smells the device inhaling volatile small molecule compound
CN105070173A (en) * 2015-07-16 2015-11-18 沈阳师范大学 Animal direct exposure indoor simulation method in low-temperature rain and snow freezing duration
CN205459178U (en) * 2016-03-20 2016-08-17 金红旭 Novel experiment of animal blast injury device
CN206725539U (en) * 2017-05-27 2017-12-08 沈阳医学院 A kind of experimental animal behavioral data collection, smell warning device

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