CN108653535A - 一种治疗风湿骨病的喷剂以及制备方法 - Google Patents

一种治疗风湿骨病的喷剂以及制备方法 Download PDF

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CN108653535A
CN108653535A CN201810663817.5A CN201810663817A CN108653535A CN 108653535 A CN108653535 A CN 108653535A CN 201810663817 A CN201810663817 A CN 201810663817A CN 108653535 A CN108653535 A CN 108653535A
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parts
radix
spray
rhizoma
bone disease
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李会道
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Chuzhou Nine Ding Tang Biotechnology Co Ltd
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Chuzhou Nine Ding Tang Biotechnology Co Ltd
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Abstract

本发明涉及一种治疗风湿骨病的喷剂以及制备方法，所述的喷剂的原料按照重量份计包括：透骨草4‑8份、龙血竭2‑3份、地龙1‑1.5份、当归6‑8份、红花2‑5份、骨碎补4‑7份、乌梅2‑5份、乌梢蛇4‑6份、土鳖虫3‑5份、甘草1‑3份、独活4‑5份、羌活1‑4份、穿破石5‑8份、川芎5‑8份、威灵仙6‑8份、乳香2‑4份、没药2‑8份、艾叶10‑12份、樟脑3‑5份、冰片2‑3份、皂角刺1‑4份、朝天椒2‑3份、延胡索3‑5份、细辛4‑6份、鸡血藤5‑8份、麻黄3‑5份、川牛膝1‑2份、秦艽4‑7份、木瓜4‑8份、白术3‑5份、仙鹤草3‑5份。

Description

一种治疗风湿骨病的喷剂以及制备方法
技术领域
本发明涉及中药领域，尤其是涉及一种治疗风湿骨病的喷剂以及制备方法。
背景技术
目前，透骨草是一种治疗各种风湿骨病特效纯中药产品，系精选本地地道野生草药和多种名贵中药材，具有活血化瘀、祛风除湿、 消肿止痛、通经活络、温经散寒、驱风除痹、接骨续筋、强筋壮骨、软坚散结 、修复损伤、补肝益肾、增强免疫 、平衡阴阳等功效，并能扶正固本，标本兼治，改善颈、腰椎、肩、关节等部位的血液循环，抑制问题部位的增生，减少发病，拔除骨层深处的风寒湿毒等显著作用。
透骨草是一种治疗各种风湿骨病特效纯中药产品，系精选本地地道野生草药和多种名贵中药材，采用传统独特制作方法并结合现代工艺萃取药液精华精致而成的外用搽剂。中医认为，“通则不痛，痛则不通”，“痹毒不除，痹症难愈”，因而透骨草抑菌喷剂另辟蹊径，以拔毒通络，补骨益肾为最佳治疗选择，全面排除肌肉、骨髓和经络之毒，并助之于强筋壮骨、舒筋活络、通痹止痛、祛风除湿、散瘀镇痛、接骨续筋、平衡免疫、益气活血、滋养肝肾，以达“攻补结合、排补互济、固本扶正”和“修改关节、抑制病情、斩断病源、防止复发”之疗效。
该品绝不含有任何激素、抗生素和西药止痛成分，疗效卓著；通过追风除湿、修复损伤、软坚散结、溶解增生、调节代谢、温阳补肾、提高免疫等多重手段，最终实现对风湿骨病等疾病的标本兼治。具有起效迅速、止痛快、疗程短、治愈率高、功能恢复快、愈后不反弹、复发率低、渗透性强、无毒副作用等优势。
发明内容
本发明的目的是提供一种风湿骨病的抑菌喷剂以及制备方法，解决骨性关节炎、腰椎病、颈椎病、肩周炎、风湿性关节炎、类风湿性关节炎、骨质增生、腰椎间盘突出、椎管狭窄、痛风、股骨头坏死、强直性脊柱炎、坐骨神经痛、滑膜炎、腱鞘炎、网球肘、腰肌劳损、偏瘫、四肢麻木、闪腰岔气、骨折、跌打损伤等风湿骨病的问题。
本发明解决其技术问题所采用的技术方案是：一种治疗风湿骨病的喷剂，其特征在于：所述的风湿骨病的抑菌喷剂的原料按照重量份计包括：透骨草4-8份、龙血竭2-3份、地龙1-1.5份、当归6-8份、红花2-5份、骨碎补4-7份、乌梅2-5份、乌梢蛇4-6份、土鳖虫3-5份、甘草1-3份、独活4-5份、羌活1-4份、穿破石5-8份、川芎5-8份、威灵仙6-8份、乳香2-4份、没药2-8份、艾叶10-12份、樟脑3-5份、冰片2-3份、皂角刺1-4份、朝天椒2-3份、延胡索3-5份、细辛4-6份、鸡血藤5-8份、麻黄3-5份、川牛膝1-2份、秦艽4-7份、木瓜4-8份、白术3-5份、仙鹤草3-5份.
所述的治疗风湿骨病的喷剂以及制备方法，其特征在于：包括一下步骤：
1）投料浸泡
把权1中龙血竭、地龙、当归、红花、骨碎补、乌梅、乌梢蛇、土鳖虫、甘草、独活、羌活、穿破石、川芎、威灵仙、乳香、没药、艾叶、透骨草、皂角刺、朝天椒、延胡索、细辛、鸡血藤、麻黄、川牛膝、秦艽、木瓜、白术、仙鹤草的中药组份按比例后；再进过100-120目的粉碎机分别进行100-120目的粉状破碎，再投放入75%医用酒精中充分搅拌混合并密封，75%医用酒精与中药原料比为5：1；
2）搅拌：浸泡15天，浸泡时间内每天充分搅拌或晃动一次；
3）过滤静置分离：在浸泡时间结束后，用200目的筛子过滤，随后 按原定比例添加冰片和樟脑并充分搅拌，所得溶液静置24小时澄清， 静置时间完成后，把各静置容器中澄清的原液与下面的沉淀物分离并统一倒在一个大的容器中备用；
4）添加氮酮
添加氮酮量是原液总重量×3%按原液总重量的3%添加月桂氮卓酮（并充分搅拌后制的风湿骨病的喷剂。
本发明的有益效果：本制剂具有活血化瘀、祛风除湿、 消肿止痛、通经活络、温经散寒、驱风除痹、接骨续筋、强筋壮骨、软坚散结 、修复损伤、补肝益肾、增强免疫 、平衡阴阳等功效，并能扶正固本，标本兼治，改善颈、腰椎、肩、关节等部位的血液循环，抑制问题部位的增生，减少发病，拔除骨层深处的风寒湿毒等显著作用。
以下将结合实施例，对本发明进行较为详细的说明。
具体实施方式
实施例1，一种治疗风湿骨病的喷剂，其特征在于：所述的风湿骨病的抑菌喷剂的原料按照重量份计包括：透骨草4-8份、龙血竭2-3份、地龙1-1.5份、当归6-8份、红花2-5份、骨碎补4-7份、乌梅2-5份、乌梢蛇4-6份、土鳖虫3-5份、甘草1-3份、独活4-5份、羌活1-4份、穿破石5-8份、川芎5-8份、威灵仙6-8份、乳香2-4份、没药2-8份、艾叶10-12份、樟脑3-5份、冰片2-3份、皂角刺1-4份、朝天椒2-3份、延胡索3-5份、细辛4-6份、鸡血藤5-8份、麻黄3-5份、川牛膝1-2份、秦艽4-7份、木瓜4-8份、白术3-5份、仙鹤草3-5份.
所述的治疗风湿骨病的喷剂的制备方法，其特征在于：包括一下步骤：
1）投料浸泡
把权1中龙血竭、地龙、当归、红花、骨碎补、乌梅、乌梢蛇、土鳖虫、甘草、独活、羌活、穿破石、川芎、威灵仙、乳香、没药、艾叶、透骨草、皂角刺、朝天椒、延胡索、细辛、鸡血藤、麻黄、川牛膝、秦艽、木瓜、白术、仙鹤草的中药组份按比例后；再进过100-120目的粉碎机分别进行100-120目的粉状破碎，再投放入75%医用酒精中充分搅拌混合并密封，75%医用酒精与中药原料比为5：1；
4）搅拌：浸泡15天，浸泡时间内每天充分搅拌或晃动一次；
5）过滤静置分离：在浸泡时间结束后，用200目的筛子过滤，随后按原定比例添加冰片和樟脑并充分搅拌，所得溶液静置24小时澄清， 静置时间完成后，把各静置容器中澄清的原液与下面的沉淀物分离并统一倒在一个大的容器中备用；
4）添加氮酮
添加氮酮量是原液总重量×3%按原液总重量的3%添加月桂氮卓酮（并充分搅拌后制的风湿骨病的喷剂。
本制剂具有活血化瘀、祛风除湿、 消肿止痛、通经活络、温经散寒、驱风除痹、接骨续筋、强筋壮骨、软坚散结 、修复损伤、补肝益肾、增强免疫 、平衡阴阳等功效，并能扶正固本，标本兼治，改善颈、腰椎、肩、关节等部位的血液循环，抑制问题部位的增生，减少发病，拔除骨层深处的风寒湿毒等显著作用。
能够快速消除各种酸、麻、僵、肿、痛等症状，喷药后一般1-24小时内见效；半个月为一个疗程，一般轻症患者1个疗程可以痊愈，重症患者2-4个疗程左右痊愈，治愈率高，复发率低。
使用方法
直接喷于痛处（压痛点），面积约大于疼痛处2-4倍，每次4-6喷，以喷雾均匀不流滴为宜，适当按摩或拍打。一日2-3次。
风湿骨病多为慢性病，非几日就能治愈的，药到病除有一个过程，甚至有的患者在治疗过程中起效慢也是正常。所以需要患者的坚持和配合。即便患者康复了，建议最好再加1-2个疗程以便巩固和防复发。
以上所述仅为本发明的较佳实施例，凡依本发明权利要求范围所做的均等变化，皆应属本发明权利要求的涵盖范围。

Claims (2)

1.一种治疗风湿骨病的喷剂，其特征在于：所述的风湿骨病的抑菌喷剂的原料按照重量份计包括：透骨草4-8份、龙血竭2-3份、地龙1-1.5份、当归6-8份、红花2-5份、骨碎补4-7份、乌梅2-5份、乌梢蛇4-6份、土鳖虫3-5份、甘草1-3份、独活4-5份、羌活1-4份、穿破石5-8份、川芎5-8份、威灵仙6-8份、乳香2-4份、没药2-8份、艾叶10-12份、樟脑3-5份、冰片2-3份、皂角刺1-4份、朝天椒2-3份、延胡索3-5份、细辛4-6份、鸡血藤5-8份、麻黄3-5份、川牛膝1-2份、秦艽4-7份、木瓜4-8份、白术3-5份、仙鹤草3-5份。
2.根据权利要求1所述的治疗风湿骨病的喷剂的制备方法，其特征在于：包括一下步骤：
1）投料浸泡：把权1中龙血竭、地龙、当归、红花、骨碎补、乌梅、乌梢蛇、土鳖虫、甘草、独活、羌活、穿破石、川芎、威灵仙、乳香、没药、艾叶、透骨草、皂角刺、朝天椒、延胡索、细辛、鸡血藤、麻黄、川牛膝、秦艽、木瓜、白术、仙鹤草的中药组份按比例后；再进过100-120目的粉碎机分别进行100-120目的粉状破碎，再投放入75%医用酒精中充分搅拌混合并密封，75%医用酒精与中药原料比为5：1；
搅拌： 浸泡15天，浸泡时间内每天充分搅拌或晃动一次；
过滤静置分离：在浸泡时间结束后，用200目的筛子过滤，随后 按原定比例添加冰片和樟脑并充分搅拌，所得溶液静置24小时澄清， 静置时间完成后，把各静置容器中澄清的原液与下面的沉淀物分离并统一倒在一个大的容器中备用；
4）添加氮酮：添加氮酮量是原液总重量×3%按原液总重量的3%添加月桂氮卓酮并充分搅拌后制的风湿骨病的喷剂。
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111434350A (zh) * 2019-01-14 2020-07-21 蔡兰 一种主治风湿病、滑膜炎、肩周炎的速效止疼用剂

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199798A (zh) * 2006-12-11 2008-06-18 杨梅英 一种治疗风湿痛的喷雾剂
CN106421663A (zh) * 2016-11-21 2017-02-22 李永伟 一种治疗风湿骨病的药物组合物及其制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101199798A (zh) * 2006-12-11 2008-06-18 杨梅英 一种治疗风湿痛的喷雾剂
CN106421663A (zh) * 2016-11-21 2017-02-22 李永伟 一种治疗风湿骨病的药物组合物及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
徐友霞等: "中医药治疗类风湿关节炎的临床研究进展 ", 《世界中西医结合杂志》 *
高海涛等: "中医药治疗类风湿性关节炎研究进展 ", 《现代中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111434350A (zh) * 2019-01-14 2020-07-21 蔡兰 一种主治风湿病、滑膜炎、肩周炎的速效止疼用剂

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