CN108578656A - It is a kind of to be used to treat pharmaceutical composition of respiratory disease and preparation method thereof - Google Patents

It is a kind of to be used to treat pharmaceutical composition of respiratory disease and preparation method thereof Download PDF

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Publication number
CN108578656A
CN108578656A CN201810520189.5A CN201810520189A CN108578656A CN 108578656 A CN108578656 A CN 108578656A CN 201810520189 A CN201810520189 A CN 201810520189A CN 108578656 A CN108578656 A CN 108578656A
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China
Prior art keywords
parts
respiratory disease
pharmaceutical composition
pinellia
cloves
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CN201810520189.5A
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Chinese (zh)
Inventor
俞洋
徐�明
陈军
王俊
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
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Priority to CN201810520189.5A priority Critical patent/CN108578656A/en
Publication of CN108578656A publication Critical patent/CN108578656A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention discloses a kind of pharmaceutical compositions for treating respiratory disease, it is made of the bulk pharmaceutical chemicals of following parts by weight：2 ~ 3 parts of the root of Dahurain angelica, 1 ~ 2 part of the tuber of pinellia, 5 ~ 8 parts of cloves, 1 ~ 3 part of fructus choerospondiatis, 4 ~ 7 parts of Radix Astragali, 4 ~ 8 parts of wrinkled giant hyssop, 1 ~ 3 part of oriental wormwood, 1 ~ 2 part of lanatechead saussurea herb with flower, 2 ~ 5 parts of lucid asparagus, 1 ~ 4 part of ginger, 2 ~ 6 parts of fructus gardeniae, 1 ~ 3 part of loguat leaf, 3 ~ 5 parts of dandelion.The pharmaceutical composition can effectively mitigate the phenomenon that respiratory disease patient runny nose, nasal obstruction, have certain curative effect to treatment respiratory disease.

Description

It is a kind of to be used to treat pharmaceutical composition of respiratory disease and preparation method thereof
Technical field
The invention belongs to medicament for treating respiratory system object treatment technology fields, and in particular to one kind is for treating respiratory system disease The pharmaceutical composition and preparation method thereof of disease.
Background technology
Respiratory disease is acute disease, and type is various, including pulmonary tuberculosis or pulmonary infection, children's bronchopneumonia hair Capillary bronchitis, asthma etc., cardinal symptom are chronic cough, pant, generate heat, having difficulty in breathing, and have seriously affected the strong of people Health.Antiviral, anti-inflammation drugs treat this and desirable short term efficacy, but will produce drug resistance if taking for a long time.
Invention content
The technical problem to be solved by the present invention is to：A kind of pharmaceutical composition for treating respiratory disease is provided.
The present invention goes back technical problems to be solved：It provides above-mentioned for treating the pharmaceutical composition of respiratory disease Preparation method.
Technical solution：
In order to solve the above technical problems, the present invention adopts the following technical scheme that：
A kind of pharmaceutical composition for treating respiratory disease, it is made of the bulk pharmaceutical chemicals of following parts by weight：
2 ~ 3 parts of the root of Dahurain angelica, 1 ~ 2 part of the tuber of pinellia, 5 ~ 8 parts of cloves, 1 ~ 3 part of fructus choerospondiatis, 4 ~ 7 parts of Radix Astragali, 4 ~ 8 parts of wrinkled giant hyssop, 1 ~ 3 part of oriental wormwood, snow 1 ~ 2 part of lotus flower, 2 ~ 5 parts of lucid asparagus, 1 ~ 4 part of ginger, 2 ~ 6 parts of fructus gardeniae, 1 ~ 3 part of loguat leaf, 3 ~ 5 parts of dandelion.
Preferably, it is made of the bulk pharmaceutical chemicals of following parts by weight：
2 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 5 parts of cloves, 1 part of fructus choerospondiatis, 4 parts of Radix Astragali, 4 parts of wrinkled giant hyssop, 1 part of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 2 Part, 1 part of ginger, 2 parts of fructus gardeniae, 1 part of loguat leaf, 3 parts of dandelion.
Preferably, it is made of the bulk pharmaceutical chemicals of following parts by weight：
3 parts of the root of Dahurain angelica, 2 parts of the tuber of pinellia, 8 parts of cloves, 3 parts of fructus choerospondiatis, 7 parts of Radix Astragali, 8 parts of wrinkled giant hyssop, 3 parts of oriental wormwood, 2 parts of lanatechead saussurea herb with flower, lucid asparagus 5 Part, 4 parts of ginger, 6 parts of fructus gardeniae, 3 parts of loguat leaf, 5 parts of dandelion.
Preferably, it is made of the bulk pharmaceutical chemicals of following parts by weight：
3 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 6 parts of cloves, 2 parts of fructus choerospondiatis, 5 parts of Radix Astragali, 6 parts of wrinkled giant hyssop, 2 parts of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 3 Part, 2 parts of ginger, 5 parts of fructus gardeniae, 2 parts of loguat leaf, 4 parts of dandelion.
The above-mentioned preparation method for treating the pharmaceutical composition of respiratory disease includes the following steps：
(1) it weighs by weight respectively：2 ~ 3 parts of the root of Dahurain angelica, 1 ~ 2 part of the tuber of pinellia, 5 ~ 8 parts of cloves, 1 ~ 3 part of fructus choerospondiatis, 4 ~ 7 parts of Radix Astragali, 4 ~ 8 parts of wrinkled giant hyssop, 1 ~ 3 part of oriental wormwood, 1 ~ 2 part of lanatechead saussurea herb with flower, 2 ~ 5 parts of lucid asparagus, 1 ~ 4 part of ginger, 2 ~ 6 parts of fructus gardeniae, loguat leaf 1 ~ 3 Part, 3 ~ 5 parts of dandelion mix, grinding；
(2) ethanol solution of 6 ~ 10 times of volume of mixture is added in the mixture obtained to step (1), under the conditions of 40 ~ 50 DEG C 3 ~ 5h is handled, filtrate is collected in filtering, and then the ethyl alcohol in decompression removal filtrate, stands filtrate, upper layer grease is isolated Come, had both obtained the pharmaceutical composition for treating respiratory disease.
Step（2）In, the volume fraction of ethyl alcohol is 70% in the ethanol solution.
Advantageous effect：
The invention discloses the pharmaceutical composition for treating respiratory disease, which can effectively mitigate breathing system , there is certain curative effect in the phenomenon that Disease runny nose, nasal obstruction of uniting to treatment respiratory disease.
Specific implementation mode
According to following embodiments, the present invention may be better understood.However, as it will be easily appreciated by one skilled in the art that real It applies content described in example and is merely to illustrate the present invention, without sheet described in detail in claims should will not be limited Invention.
Embodiment 1：
Prescription：
2 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 5 parts of cloves, 1 part of fructus choerospondiatis, 4 parts of Radix Astragali, 4 parts of wrinkled giant hyssop, 1 part of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 2 Part, 1 part of ginger, 2 parts of fructus gardeniae, 1 part of loguat leaf, 3 parts of dandelion.
Preparation process：
(1) it weighs by weight respectively：2 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 5 parts of cloves, 1 part of fructus choerospondiatis, 4 parts of Radix Astragali, 4 parts of wrinkled giant hyssop, oriental wormwood 1 part, 1 part of lanatechead saussurea herb with flower, 2 parts of lucid asparagus, 1 part of ginger, 2 parts of fructus gardeniae, 1 part of loguat leaf, 3 parts of dandelion, mix, grinding；
(2) ethanol solution of 6 ~ 10 times of volume of mixture is added in the mixture obtained to step (1), under the conditions of 40 ~ 50 DEG C 3 ~ 5h is handled, filtrate is collected in filtering, and then the ethyl alcohol in decompression removal filtrate, stands filtrate, upper layer grease is isolated Come, had both obtained the pharmaceutical composition for treating respiratory disease.
Embodiment 2：
Prescription：
3 parts of the root of Dahurain angelica, 2 parts of the tuber of pinellia, 8 parts of cloves, 3 parts of fructus choerospondiatis, 7 parts of Radix Astragali, 8 parts of wrinkled giant hyssop, 3 parts of oriental wormwood, 2 parts of lanatechead saussurea herb with flower, lucid asparagus 5 Part, 4 parts of ginger, 6 parts of fructus gardeniae, 3 parts of loguat leaf, 5 parts of dandelion.
Preparation process：
(1) it weighs by weight respectively：3 parts of the root of Dahurain angelica, 2 parts of the tuber of pinellia, 8 parts of cloves, 3 parts of fructus choerospondiatis, 7 parts of Radix Astragali, 8 parts of wrinkled giant hyssop, oriental wormwood 3 parts, 2 parts of lanatechead saussurea herb with flower, 5 parts of lucid asparagus, 4 parts of ginger, 6 parts of fructus gardeniae, 3 parts of loguat leaf, 5 parts of dandelion, mix, grinding；
(2) ethanol solution of 6 ~ 10 times of volume of mixture is added in the mixture obtained to step (1), under the conditions of 40 ~ 50 DEG C 3 ~ 5h is handled, filtrate is collected in filtering, and then the ethyl alcohol in decompression removal filtrate, stands filtrate, upper layer grease is isolated Come, had both obtained the pharmaceutical composition for treating respiratory disease.
Embodiment 3：
Prescription：
3 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 6 parts of cloves, 2 parts of fructus choerospondiatis, 5 parts of Radix Astragali, 6 parts of wrinkled giant hyssop, 2 parts of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 3 Part, 2 parts of ginger, 5 parts of fructus gardeniae, 2 parts of loguat leaf, 4 parts of dandelion.
Preparation process：
(1) it weighs by weight respectively：3 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 6 parts of cloves, 2 parts of fructus choerospondiatis, 5 parts of Radix Astragali, 6 parts of wrinkled giant hyssop, oriental wormwood 2 parts, 1 part of lanatechead saussurea herb with flower, 3 parts of lucid asparagus, 2 parts of ginger, 5 parts of fructus gardeniae, 2 parts of loguat leaf, 4 parts of dandelion, mix, grinding；
(2) ethanol solution of 6 ~ 10 times of volume of mixture is added in the mixture obtained to step (1), under the conditions of 40 ~ 50 DEG C 3 ~ 5h is handled, filtrate is collected in filtering, and then the ethyl alcohol in decompression removal filtrate, stands filtrate, upper layer grease is isolated Come, had both obtained the pharmaceutical composition for treating respiratory disease.
The pharmaceutical composition that embodiment 1 ~ 3 is obtained is 1 according to mass ratio with sodium chloride, vitamin C, dipotassium hydrogen phosphate:0.01: 0.3:0.02 ratio mixing, then plus water is settled to 1000ml, is divided in aerosol bottle respectively, is observed after standing 7 days molten Fluidity shape has preferable dispersibility and stability.
Carry out the advantageous effect that the present invention is further explained below by clinical trial results：
100 respiratory disease patients, the aerosol for giving embodiment 1, embodiment 2 or embodiment 3 respectively are selected to be controlled It treats, control group is treated using commercially available aerosol, and usage and dosage, 5 times a day, each 0.5ml, 7 days as a course for the treatment of.
Efficacy assessment standard：
It is effective：Without nasal obstruction, runny nose phenomenon after one course for the treatment of；
Effectively：Nasal obstruction, runny nose phenomenon mitigate after one course for the treatment of, without nasal obstruction, runny nose phenomenon after two courses for the treatment of；
In vain：Nasal obstruction, runny nose phenomenon do not improve after one course for the treatment of.
The experimental results are shown inthe following table：
Group Case load It is effective Effectively In vain It is efficient
Experimental group 50 45 3 2 96%
Control group 50 20 15 15 70%

Claims (6)

1. a kind of pharmaceutical composition for treating respiratory disease, which is characterized in that it is by the raw material of following parts by weight Medicine is made：
2 ~ 3 parts of the root of Dahurain angelica, 1 ~ 2 part of the tuber of pinellia, 5 ~ 8 parts of cloves, 1 ~ 3 part of fructus choerospondiatis, 4 ~ 7 parts of Radix Astragali, 4 ~ 8 parts of wrinkled giant hyssop, 1 ~ 3 part of oriental wormwood, snow 1 ~ 2 part of lotus flower, 2 ~ 5 parts of lucid asparagus, 1 ~ 4 part of ginger, 2 ~ 6 parts of fructus gardeniae, 1 ~ 3 part of loguat leaf, 3 ~ 5 parts of dandelion.
2. the pharmaceutical composition according to claim 1 for treating respiratory disease, it is by following parts by weight Bulk pharmaceutical chemicals are made：
2 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 5 parts of cloves, 1 part of fructus choerospondiatis, 4 parts of Radix Astragali, 4 parts of wrinkled giant hyssop, 1 part of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 2 Part, 1 part of ginger, 2 parts of fructus gardeniae, 1 part of loguat leaf, 3 parts of dandelion.
3. the pharmaceutical composition according to claim 1 for treating respiratory disease, which is characterized in that it is by such as The bulk pharmaceutical chemicals of lower parts by weight are made：
3 parts of the root of Dahurain angelica, 2 parts of the tuber of pinellia, 8 parts of cloves, 3 parts of fructus choerospondiatis, 7 parts of Radix Astragali, 8 parts of wrinkled giant hyssop, 3 parts of oriental wormwood, 2 parts of lanatechead saussurea herb with flower, lucid asparagus 5 Part, 4 parts of ginger, 6 parts of fructus gardeniae, 3 parts of loguat leaf, 5 parts of dandelion.
4. the pharmaceutical composition according to claim 1 for treating respiratory disease, which is characterized in that it is by such as The bulk pharmaceutical chemicals of lower parts by weight are made：
3 parts of the root of Dahurain angelica, 1 part of the tuber of pinellia, 6 parts of cloves, 2 parts of fructus choerospondiatis, 5 parts of Radix Astragali, 6 parts of wrinkled giant hyssop, 2 parts of oriental wormwood, 1 part of lanatechead saussurea herb with flower, lucid asparagus 3 Part, 2 parts of ginger, 5 parts of fructus gardeniae, 2 parts of loguat leaf, 4 parts of dandelion.
5. the preparation method described in claim 1 for treating the pharmaceutical composition of respiratory disease, which is characterized in that packet Include following steps：
(1) it weighs by weight respectively：2 ~ 3 parts of the root of Dahurain angelica, 1 ~ 2 part of the tuber of pinellia, 5 ~ 8 parts of cloves, 1 ~ 3 part of fructus choerospondiatis, 4 ~ 7 parts of Radix Astragali, 4 ~ 8 parts of wrinkled giant hyssop, 1 ~ 3 part of oriental wormwood, 1 ~ 2 part of lanatechead saussurea herb with flower, 2 ~ 5 parts of lucid asparagus, 1 ~ 4 part of ginger, 2 ~ 6 parts of fructus gardeniae, loguat leaf 1 ~ 3 Part, 3 ~ 5 parts of dandelion mix, grinding；
(2) ethanol solution of 6 ~ 10 times of volume of mixture is added in the mixture obtained to step (1), under the conditions of 40 ~ 50 DEG C 3 ~ 5h is handled, filtrate is collected in filtering, and then the ethyl alcohol in decompression removal filtrate, stands filtrate, upper layer grease is isolated Come, had both obtained the pharmaceutical composition for treating respiratory disease.
6. the preparation method according to claim 5 for treating the pharmaceutical composition of respiratory disease, feature exists In step（2）In, the volume fraction of ethyl alcohol is 70% in the ethanol solution.
CN201810520189.5A 2018-05-28 2018-05-28 It is a kind of to be used to treat pharmaceutical composition of respiratory disease and preparation method thereof Pending CN108578656A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772778A (en) * 2012-08-20 2012-11-14 刘海霞 Chinese medicinal composition for treating summer heat-dampness
CN104971327A (en) * 2015-06-18 2015-10-14 许五妮 Traditional Chinese medicinal preparation for treating wind-heat type common cold
CN105797092A (en) * 2016-02-16 2016-07-27 张欢 Primordial qi tonifying and cold resisting mixture

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102772778A (en) * 2012-08-20 2012-11-14 刘海霞 Chinese medicinal composition for treating summer heat-dampness
CN104971327A (en) * 2015-06-18 2015-10-14 许五妮 Traditional Chinese medicinal preparation for treating wind-heat type common cold
CN105797092A (en) * 2016-02-16 2016-07-27 张欢 Primordial qi tonifying and cold resisting mixture

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