CN108553452A - 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物 - Google Patents

通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物 Download PDF

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Publication number
CN108553452A
CN108553452A CN201810750500.5A CN201810750500A CN108553452A CN 108553452 A CN108553452 A CN 108553452A CN 201810750500 A CN201810750500 A CN 201810750500A CN 108553452 A CN108553452 A CN 108553452A
Authority
CN
China
Prior art keywords
acid
drug
salt
composition according
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810750500.5A
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English (en)
Chinese (zh)
Inventor
滨本英利
山中胜弘
谷本高广
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedRx Co Ltd
Original Assignee
MedRx Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49768781&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN108553452(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MedRx Co Ltd filed Critical MedRx Co Ltd
Publication of CN108553452A publication Critical patent/CN108553452A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201810750500.5A 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物 Pending CN108553452A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-139215 2012-06-20
JP2012139215 2012-06-20
CN201380031729.9A CN104363900A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380031729.9A Division CN104363900A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物

Publications (1)

Publication Number Publication Date
CN108553452A true CN108553452A (zh) 2018-09-21

Family

ID=49768781

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201810750500.5A Pending CN108553452A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物
CN201911053677.0A Pending CN110693859A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物
CN201380031729.9A Pending CN104363900A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201911053677.0A Pending CN110693859A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物
CN201380031729.9A Pending CN104363900A (zh) 2012-06-20 2013-06-18 通过掺混药物、有机溶剂、亲脂性基质和粉末获得的粘附制剂组合物

Country Status (16)

Country Link
US (2) US10543275B2 (https=)
EP (1) EP2865376B2 (https=)
JP (1) JP6309892B2 (https=)
CN (3) CN108553452A (https=)
AU (1) AU2013278403B2 (https=)
BR (1) BR112014031701A2 (https=)
CA (1) CA2875454C (https=)
DK (1) DK2865376T4 (https=)
ES (1) ES2738303T5 (https=)
HU (1) HUE045479T2 (https=)
IN (1) IN2014DN10706A (https=)
PL (1) PL2865376T5 (https=)
PT (1) PT2865376T (https=)
SI (1) SI2865376T1 (https=)
TR (1) TR201911328T4 (https=)
WO (1) WO2013191187A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015037639A1 (ja) * 2013-09-11 2015-03-19 株式会社 メドレックス テープ剤の新規な基剤組成物
CN103830206B (zh) * 2014-02-26 2016-08-31 上海现代药物制剂工程研究中心有限公司 阿戈美拉汀三维网状立体构型的透皮给药制剂及制备方法
JPWO2015129527A1 (ja) * 2014-02-27 2017-03-30 株式会社 メドレックス プラミペキソールを含有する神経変性疾患の治療用貼付剤
WO2016109483A1 (en) * 2014-12-30 2016-07-07 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems for agomelatine
US10016502B2 (en) 2015-08-29 2018-07-10 Medrx Co., Ltd Patch preparation containing an acid scavenger
WO2017037812A1 (ja) * 2015-08-29 2017-03-09 株式会社メドレックス 酸捕捉剤を含有する貼付製剤
WO2017037813A1 (ja) * 2015-08-29 2017-03-09 株式会社メドレックス 塩基性薬物とソルビン酸とを含有する経皮吸収組成物
US20170273974A1 (en) 2016-03-24 2017-09-28 Medrx Co., Ltd Patch preparations with misuse prevention features
CN108883078B (zh) * 2016-03-24 2022-09-09 美德阿利克斯株式会社 具有防止误用特性的贴剂
US11642247B2 (en) 2016-11-09 2023-05-09 Kuraray Co., Ltd. Pressure-sensitive adhesive sheet, adhesive bandage, and method of producing the same
WO2020071546A1 (ja) * 2018-10-04 2020-04-09 株式会社 メドレックス 非水系溶媒により安定化された製剤
EP4292583A4 (en) * 2021-02-12 2024-12-18 MEDRx Co., Ltd. COMPOSITION WITH IMPROVED ABSORBABILITY OF A POORLY ABSORBABLE MEDICINAL PRODUCT
JP7179212B1 (ja) * 2022-05-02 2022-11-28 久光製薬株式会社 リドカイン含有貼付剤

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503532B1 (en) * 2001-04-13 2003-01-07 Murty Pharmaceuticals, Inc. Pharmaceutical composition containing tetrahydrocannabinol and a transdermal/transcutaneous delivery method thereof
WO2010113225A1 (en) * 2009-03-30 2010-10-07 Yutoku Pharmaceutical Industries Co., Ltd. Riluzole-containing transdermal patch
CN101909651A (zh) * 2007-11-22 2010-12-08 美德阿利克斯株式会社 包括基于脂肪酸的离子型液体作为活性成分的外用制剂组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3144895B2 (ja) 1992-06-30 2001-03-12 積水化学工業株式会社 医療用粘着テープもしくはシート
JPH06145050A (ja) * 1992-11-11 1994-05-24 Sekisui Chem Co Ltd 貼付剤の製造方法
JPH07145047A (ja) 1993-11-25 1995-06-06 Sekisui Chem Co Ltd 局所麻酔用経皮吸収テープ
JPH0827003A (ja) 1994-07-22 1996-01-30 Sekisui Chem Co Ltd 経皮吸収製剤
JPH09169636A (ja) 1995-06-12 1997-06-30 Sekisui Chem Co Ltd 貼付剤
JPH09136834A (ja) 1995-11-14 1997-05-27 Sekisui Chem Co Ltd 経皮吸収貼付剤
JP4648518B2 (ja) * 2000-06-01 2011-03-09 帝國製薬株式会社 ４−ビフェニル酢酸含有貼付剤
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
AU2003272878A1 (en) * 2002-09-13 2004-04-30 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
US20060036220A1 (en) * 2003-01-22 2006-02-16 Kohji Kawahara Percutaneous absorption preparation for treating ophthalmic disease, use thereof and method for migration of ophthalmic remedy into topical tissue in eye
US8080261B2 (en) * 2004-09-30 2011-12-20 Teikoku Pharma Usa, Inc. 1-chloro-2,4-dinitrobenzene non-aqueous gel compositions and methods for using the same
US20090258063A1 (en) * 2006-09-11 2009-10-15 Sekisui Chemical Co., Ltd. Transdermal patch
WO2008032719A1 (en) 2006-09-11 2008-03-20 Sekisui Chemical Co., Ltd. Adhesive preparation
EP2258396B1 (en) 2008-03-03 2017-09-06 Hisamitsu Pharmaceutical Co., Inc. Transdermally absorbable preparation
JP4822032B2 (ja) 2009-01-08 2011-11-24 タイヨーエレック株式会社 組合せ式遊技機
DE102009022915A1 (de) * 2009-05-27 2010-12-09 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit gesteuertem Wirkstofffluss
JP2011074035A (ja) * 2009-09-30 2011-04-14 Sekisui Medical Co Ltd 貼付剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503532B1 (en) * 2001-04-13 2003-01-07 Murty Pharmaceuticals, Inc. Pharmaceutical composition containing tetrahydrocannabinol and a transdermal/transcutaneous delivery method thereof
CN101909651A (zh) * 2007-11-22 2010-12-08 美德阿利克斯株式会社 包括基于脂肪酸的离子型液体作为活性成分的外用制剂组合物
WO2010113225A1 (en) * 2009-03-30 2010-10-07 Yutoku Pharmaceutical Industries Co., Ltd. Riluzole-containing transdermal patch

Also Published As

Publication number Publication date
DK2865376T3 (da) 2019-08-12
HUE045479T2 (hu) 2019-12-30
EP2865376B1 (en) 2019-06-05
PT2865376T (pt) 2019-08-26
JP6309892B2 (ja) 2018-04-11
CA2875454A1 (en) 2013-12-27
PL2865376T3 (pl) 2019-12-31
US12016924B2 (en) 2024-06-25
AU2013278403B2 (en) 2018-02-01
CN110693859A (zh) 2020-01-17
WO2013191187A1 (ja) 2013-12-27
ES2738303T5 (es) 2022-09-12
US20150174249A1 (en) 2015-06-25
JPWO2013191187A1 (ja) 2016-05-26
US10543275B2 (en) 2020-01-28
EP2865376A1 (en) 2015-04-29
PL2865376T5 (pl) 2023-01-09
EP2865376A4 (en) 2015-11-18
US20190388544A1 (en) 2019-12-26
CN104363900A (zh) 2015-02-18
AU2013278403A1 (en) 2015-01-22
SI2865376T1 (sl) 2019-11-29
IN2014DN10706A (https=) 2015-09-04
ES2738303T3 (es) 2020-01-21
TR201911328T4 (tr) 2019-08-21
DK2865376T4 (da) 2022-07-18
CA2875454C (en) 2021-02-16
EP2865376B2 (en) 2022-05-11
BR112014031701A2 (pt) 2017-06-27

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Application publication date: 20180921