CN108477168A - A kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing - Google Patents
A kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing Download PDFInfo
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- CN108477168A CN108477168A CN201810423328.2A CN201810423328A CN108477168A CN 108477168 A CN108477168 A CN 108477168A CN 201810423328 A CN201810423328 A CN 201810423328A CN 108477168 A CN108477168 A CN 108477168A
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- phenylancryic acetate
- fenhexamid
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
- A01N37/22—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof the nitrogen atom being directly attached to an aromatic ring system, e.g. anilides
- A01N37/24—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof the nitrogen atom being directly attached to an aromatic ring system, e.g. anilides containing at least one oxygen or sulfur atom being directly attached to the same aromatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
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Abstract
Two classes are had the fungicide of different role mechanism by the present invention, i.e. 2-cyano-3-amino-3-phenylancryic acetate and fenhexamid or Guardian are combined, and it is processed into the upper easy-to-use preparation of production, it compares in two kinds of ingredient exclusive uses, with bioactivity height, total dosage declines on unit area, greatly reduce dispenser cost, pathogen drug resistance is delayed to generate and develop to a greater extent simultaneously, reduce the risk that disease fungus generates single bactericide resistance, extend the service life of each component in bactericidal composition, to realize economy, efficiently, the goal of the invention of environmental protection.
Description
Technical field
The present invention relates to disinfectant use in agriculture fields, and in particular to a kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing.
Background technology
Bakanae disease of rice and seedling seasonal febrile diseases are the most important two kinds of diseases of rice seedling, the large area of both diseases occurs past
Toward dropping in production over a large area for rice is caused, total crop failure is often resulted in when endangering serious.Bakanae disease of rice is also known as excessive growth disease, is rice seedling
One of Common Diseases, seed and soil disease propagation are to endanger its main cause in spite of illness, and cardinal symptom is morbidity sick seedling than strong
Kang Miao is thin and tall, and blade leaf sheath is elongated, and leaf color is yellowish, and root system development is bad, and part sick seedling is dead before transplanting；Peel off leaf sheath, stem
There are crineous streak, the inside visible white spider's thread shape mycelia on stalk.Before rice seedlings seasonal febrile diseases are happened at tri-leaf period, by seed-borne fungi institute
It causes, sick seedling base portion grey black, top browning, crispaturas and dead, generation a large amount of grey black mould layers in disease portion when humidity is larger.
2-cyano-3-amino-3-phenylancryic acetate belongs to 2- cyanoacrylate fungicide, effective to disease caused by sickle-like bacteria, has protection and controls
Treatment acts on, translocatable upwards by with not absorbing, having on blade, can towards blade lower part and interlobate translocatable poor
With diseases such as the brown foot rots, root-rot and marrow necrosis of effectively preventing the crops such as tomato, cucumber.
Fenhexamid belongs to acid amide fungicides, belongs to interior suction, protective fungicide.It is mainly used for rice field prevention rice blast
Sick, various gray molds etc., have special efficacy to gray mold.Formation of the Guardian to the phytophthora history of life and mycelial growth and spore
There are a very high inhibition in two stages, but phytophthora sporangium is sprouted, the growth of sporangiocyst and zoospore almost without
Any activity.
There is presently no by 2-cyano-3-amino-3-phenylancryic acetate and fenhexamid or Guardian composite usage in the report of controlling plant diseases.
Invention content
The present invention provides a kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing, have bactericidal activity high, and dosage is small, to making
Object growth has special efficacy without influence, feature economic, efficiently, environmentally friendly to prevention bakanae disease of rice and seedling seasonal febrile diseases.
Two classes are had the fungicide of different role mechanism, i.e. 2-cyano-3-amino-3-phenylancryic acetate and fenhexamid or Guardian phase by the present invention
Combination, and it is processed into the upper easy-to-use preparation of production, it compares in two kinds of ingredient exclusive uses, it is high with bioactivity, it is single
The upper total dosage of plane product declines, and greatly reduces dispenser cost, while pathogen drug resistance being delayed to produce to a greater extent
Raw and development reduces the risk that disease fungus generates single bactericide resistance, extends each component in bactericidal composition
Service life, to realize goal of the invention economic, efficiently, environmentally friendly.
The technical scheme is that：
A kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing, which is characterized in that the active component A of the microbicide compositions is cyanogen alkene
Bacterium ester, B are any one in fenhexamid or Guardian, and the mass ratio of A and B are 1：40 to 40:1.
The microbicide compositions of the 2-cyano-3-amino-3-phenylancryic acetate-containing, it is characterised in that：The active component A of the microbicide compositions
For 2-cyano-3-amino-3-phenylancryic acetate, B is any one in fenhexamid or Guardian, and the mass ratio of A and B are 1：5 to 5:1.
The microbicide compositions of the 2-cyano-3-amino-3-phenylancryic acetate-containing, it is characterised in that：The dosage form of the microbicide compositions is outstanding
Floating agent, missible oil, water dispersible granules, wettable powder, seed coat agent or microcapsule suspending agent.
The microbicide compositions of the 2-cyano-3-amino-3-phenylancryic acetate-containing, it is characterised in that：This microbicide compositions is to wheat, rice etc.
Various crop disease has good control effect.
The present invention remarkable result and advantage be：
The present invention has a higher control effect to bakanae disease of rice and leaf seasonal febrile diseases, and there are notable synergistic effects between two components；It can
Instead of part high price pesticide species, and dosage is reduced, effectively reduces ecological disruption and environmental pollution, and can improve and make produce
Amount and quality；It can delay drug resistance of the germ to single medicament.
2-cyano-3-amino-3-phenylancryic acetate, fenhexamid and benzene metsulfovax single compound are measured first（Hereinafter referred to as medicament）EC50（Drug
Safety indexes）, according to the EC of two single medicaments50The portfolio ratio of two medicaments is set by Sun Yunpei's Method, and according to co-toxicity coefficient
CTC values determine suitable composition ratio.
Test objective object be rice blast, bakanae disease of rice, but not limited to this.Experiment uses mycelial growth rate method,
Pastille culture medium is made by different disposal, respectively handles 4 repetitions, after connecing bacterium 3 days, investigates life of each processing to wheat rust germ
Long inhibition.By the linear regression analysis between the probit value and the logarithm of serial drug concentration of preventive effect, each medicine is found out
The EC of agent50, co-toxicity coefficient is calculated according to the abundant methods of Sun Yun（CTC）, and overall merit is made accordingly.CTC≤80 indicates there is antagonism
Effect, 80 ＜ CTC ＜ 120 indicate there is summation action, and CTC >=120 are synergistic effect.CTC value calculating methods are as follows：
The EC of CTC=A50* the EC of B50*100/（The EC50* of M（PA* the EC of B50+PB* the EC of A50））
The indoor biometrics result of 1 2-cyano-3-amino-3-phenylancryic acetate of table and fenhexamid and its compounding to rice blast
| Proportioning（A：B） | Slope value（±SE） | Related coefficient | EC50（mg/L） | CTC |
| 2-cyano-3-amino-3-phenylancryic acetate（A） | 1.724±0.007 | 0.987 | 15.32 | - |
| Fenhexamid（B） | 1.011±0.006 | 0.989 | 0.784 | - |
| 40:1 | 2.241±0.013 | 0.986 | 8.156 | 129.35 |
| 10:1 | 1.632±0.031 | 0.996 | 4.632 | 123.16 |
| 5:1 | 1.357±0.016 | 0.991 | 2.112 | 177.35 |
| 1:1 | 1.526±0.014 | 0.983 | 1.123 | 132.83 |
| 1:5 | 1.623±0.022 | 0.987 | 0.712 | 130.80 |
| 1:10 | 1.512±0.010 | 0.987 | 0.674 | 127.30 |
| 1:40 | 1.414±0.004 | 0.990 | 0.654 | 122.72 |
As can be seen from the above data, the fungistatic effect of the 2-cyano-3-amino-3-phenylancryic acetate of different proportion and fenhexamid composition to Pyricularia oryzae
Different, on the whole, ratio is 40:1 to 1:There is synergistic effect in the range of 40, wherein maximum enhancing proportions are 5:
1, CTC value is 177.35.
The indoor biometrics result of 2 2-cyano-3-amino-3-phenylancryic acetate of table and Guardian and its compounding to rice blast
| Proportioning（A：B） | Slope value（±SE） | Related coefficient | EC50（mg/L） | CTC |
| 2-cyano-3-amino-3-phenylancryic acetate（A） | 1.724±0.007 | 0.987 | 15.32 | - |
| Guardian（B） | 2.176±0.016 | 0.991 | 3.147 | - |
| 40:1 | 2.241±0.013 | 0.986 | 11.27 | 124.22 |
| 10:1 | 1.632±0.031 | 0.996 | 8.762 | 129.36 |
| 5:1 | 1.357±0.016 | 0.991 | 5.647 | 164.95 |
| 1:1 | 1.526±0.014 | 0.983 | 4.125 | 126.58 |
| 1:5 | 1.623±0.022 | 0.987 | 2.987 | 121.44 |
| 1:10 | 1.512±0.010 | 0.987 | 2.741 | 123.75 |
| 1:40 | 1.414±0.004 | 0.990 | 2.547 | 126.00 |
From table 2 it can be seen that the 2-cyano-3-amino-3-phenylancryic acetate and Guardian composition of different proportion to Pyricularia oryzae its ratio 40:1 arrives
1:There is synergistic effect in the range of 40, wherein maximum enhancing proportions are 5:1, CTC value is 164.95.
The indoor biometrics result of 3 2-cyano-3-amino-3-phenylancryic acetate of table and fenhexamid and its compounding to bakanae disease
| Proportioning（A：B） | Slope value（±SE） | Related coefficient | EC50（mg/L） | CTC |
| 2-cyano-3-amino-3-phenylancryic acetate（A） | 1.124±0.005 | 0.987 | 0.139 | - |
| Fenhexamid（B） | 1.654±0.011 | 0.991 | 20.34 | - |
| 40:1 | 2.241±0.013 | 0.986 | 0.117 | 121.75 |
| 10:1 | 1.632±0.031 | 0.996 | 0.119 | 128.40 |
| 5:1 | 1.357±0.016 | 0.991 | 0.124 | 134.33 |
| 1:1 | 1.526±0.014 | 0.983 | 0.214 | 129.02 |
| 1:5 | 1.623±0.022 | 0.987 | 0.541 | 149.07 |
| 1:10 | 1.512±0.010 | 0.987 | 1.012 | 141.42 |
| 1:40 | 1.414±0.004 | 0.990 | 3.567 | 125.47 |
From table 3 it can be seen that the 2-cyano-3-amino-3-phenylancryic acetate and fenhexamid composition of different proportion to Fusarium moniliforme Sheld its ratio 40:1 arrives
1:There is synergistic effect in the range of 40, wherein maximum enhancing proportions are 1:5, CTC values are 149.07.
The indoor biometrics result of 4 2-cyano-3-amino-3-phenylancryic acetate of table and Guardian and its compounding to bakanae disease
| Proportioning（A：B） | Slope value（±SE） | Related coefficient | EC50（mg/L） | CTC |
| 2-cyano-3-amino-3-phenylancryic acetate（A） | 1.124±0.005 | 0.987 | 0.139 | - |
| Guardian（B） | 1.633±0.011 | 0.989 | 13.27 | - |
| 40:1 | 1.241±0.003 | 0.986 | 0.114 | 124.94 |
| 10:1 | 1.629±0.011 | 0.996 | 0.120 | 127.28 |
| 5:1 | 1.337±0.006 | 0.991 | 0.135 | 123.30 |
| 1:1 | 1.369±0.014 | 0.983 | 0.216 | 127.37 |
| 1:5 | 1.952±0.012 | 0.996 | 0.502 | 157.87 |
| 1:10 | 1.313±0.010 | 0.977 | 1.112 | 124.46 |
| 1:40 | 1.014±0.004 | 0.990 | 3.336 | 120.39 |
From table 4, it can be seen that the 2-cyano-3-amino-3-phenylancryic acetate and Guardian composition of different proportion to Fusarium moniliforme Sheld its ratio 40:1 arrives
1:There is synergistic effect in the range of 40, wherein maximum enhancing proportions are 1:5, CTC values are 157.87.
With reference to embodiment, the invention will be further described, it is contemplated that 2-cyano-3-amino-3-phenylancryic acetate and fenhexamid and Guardian
Processing complexity and price factor, this experiment determine use 1:5 proportioning as the two mixture, but not limited to this.It is real
The content for applying active ingredient involved in example is also not necessarily limited to this.
Specific implementation mode
(the 30% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid suspending agent of embodiment 1）
Composition of raw materials：By mass percentage
Active component 2-cyano-3-amino-3-phenylancryic acetate 5%
Active component fenhexamid 25%
NNO 3%
BY110 2%
APE-1 2%
Xanthans 0.15%
Propylene glycol 1%
Octanol 0.05%
Water surplus.
Preparation method is as follows：
According to formula, component is weighed in proportion, ball mill ball milling is added 30 minutes, filtering is pumped into dispersion tank high speed shear 3 and divides
Be fully ground through sand mill after clock, control solid component particle diameter stirred evenly within 2 microns, after grinding to get
Suspending agent product.
(the 60% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid missible oil of embodiment 2）
Composition of raw materials：By mass percentage
Active component 2-cyano-3-amino-3-phenylancryic acetate 10%
Active component fenhexamid 50%
Dimethylbenzene 20%
DMF 2%
Anhydrous calcium salt 5%
Tween 80 5%
Carbon tetrachloride surplus.
Preparation method：Active component 2-cyano-3-amino-3-phenylancryic acetate is fully dissolved in dimethylbenzene reaction kettle, A liquid is made；By activearm
Divide fenhexamid fully to be dissolved in carbon tetrachloride and DMF reaction kettles, B liquid is made；A liquid is mixed into B under the state that keeps stirring
Liquid stirs, and anhydrous calcium salt and Tween 80 is added, and then solvent carbon tetrachloride is used to adjust content.
Embodiment 3（30% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid water dispersible granules）
Active component 2-cyano-3-amino-3-phenylancryic acetate 5%
Active component fenhexamid 25%
Methyl fatty amide benzene sulfonic acid calcium 4%
Sodium carbonate 3%
Sodium lignin sulfonate 4%
Attapulgite surplus.
Preparation method：Active component, Methyl fatty amide benzene sulfonic acid calcium, sodium carbonate, attapulgite are mixed together uniformly
Afterwards, it is crushed to 5 μm of grain size through airslide disintegrating mill, obtains female powder, be granulated, dry after female powder and sodium lignin sulfonate are sufficiently mixed,
Sieving, to which water-dispersible granules be made.
Embodiment 4（60% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid wettable powder）
Active component 2-cyano-3-amino-3-phenylancryic acetate 10%
Active component fenhexamid 50%
The wooden sodium 3%
Amine carbonate 3%
White carbon 10%
Attapulgite surplus.
Preparation method：Above-mentioned substance is uniformly mixed, mixture is crushed through airslide disintegrating mill, and wettable powder is made.
Embodiment 5（12% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid microcapsule suspending agent）
Active component 2-cyano-3-amino-3-phenylancryic acetate 2%
Active component fenhexamid 10%
Dimethylformamide 2%
Methyl diphenylene diisocyanate 3%
Fatty acid amide N methyl taurine sodium salt 2%
Hexamethylene diamine 0.5%
Gum arabic 2%
Polyvinyl alcohol 2%
Water polishing is to 100%
（1）2-cyano-3-amino-3-phenylancryic acetate and fenhexamid are dissolved in solvent, methyl diphenylene diisocyanate is added and is uniformly mixing to obtain
Oil phase；（2）Emulsifier is added in water, adjuvant is uniformly mixing to obtain water phase；（3）Water phase is added in oil phase, high speed homogenizing
Form oil-in-water emulsion；（4）Under 450 revs/min of speed conditions, ethylenediamine is added and participates in interface polymerization reaction, reaction temperature liter
To 55 DEG C, 3 hours solidification encystation are kept；（5）Dispersant, thickener is added, stirs evenly and microcapsule suspending agent is made.
Embodiment 6（24% 2-cyano-3-amino-3-phenylancryic acetate fenhexamid suspension seed-coating agent）
Active component 2-cyano-3-amino-3-phenylancryic acetate 4%
Active component fenhexamid 20%
NNO 3%
BY110 2%
APE-1 2%
Xanthans 0.15%
Propylene glycol 1%
Film forming agent 3%
Dyestuff 4%
Water surplus.
According to formula, by component（Except dyestuff, film forming agent）It weighs in proportion, ball mill ball milling is added 30 minutes, filtering,
It is pumped into dispersion tank high speed shear to be fully ground through sand mill after 3 minutes, control solid component particle diameter is ground within 2 microns
It is stirred evenly after mill, film forming agent and dyestuff is added to get suspension seed-coating agent product.
(the 30% 2-cyano-3-amino-3-phenylancryic acetate Guardian suspending agent of embodiment 7）
Composition of raw materials：By mass percentage
Active component 2-cyano-3-amino-3-phenylancryic acetate 5%
Active component Guardian 25%
NNO 3%
BY110 2%
APE-1 2%
Xanthans 0.15%
Propylene glycol 1%
Octanol 0.05%
Water surplus.
Preparation method is as follows：
According to formula, component is weighed in proportion, ball mill ball milling is added 30 minutes, filtering is pumped into dispersion tank high speed shear 3 and divides
Be fully ground through sand mill after clock, control solid component particle diameter stirred evenly within 2 microns, after grinding to get
Suspending agent product.
(the 60% 2-cyano-3-amino-3-phenylancryic acetate Guardian missible oil of embodiment 8）
Composition of raw materials：By mass percentage
Active component 2-cyano-3-amino-3-phenylancryic acetate 10%
Active component Guardian 50%
Dimethylbenzene 20%
DMF 2%
Anhydrous calcium salt 5%
Tween 80 5%
Carbon tetrachloride surplus.
Preparation method：Active component 2-cyano-3-amino-3-phenylancryic acetate is fully dissolved in dimethylbenzene reaction kettle, A liquid is made；By activearm
Divide Guardian fully to be dissolved in carbon tetrachloride and DMF reaction kettles, B liquid is made；A liquid is mixed into B under the state that keeps stirring
Liquid stirs, and anhydrous calcium salt and Tween 80 is added, and then solvent carbon tetrachloride is used to adjust content.
Embodiment 9（30% 2-cyano-3-amino-3-phenylancryic acetate Guardian water dispersible granules）
Active component 2-cyano-3-amino-3-phenylancryic acetate 5%
Active component Guardian 25%
Methyl fatty amide benzene sulfonic acid calcium 4%
Sodium carbonate 3%
Sodium lignin sulfonate 4%
Attapulgite surplus.
Preparation method：Active component, Methyl fatty amide benzene sulfonic acid calcium, sodium carbonate, attapulgite are mixed together uniformly
Afterwards, it is crushed to 5 μm of grain size through airslide disintegrating mill, obtains female powder, be granulated, dry after female powder and sodium lignin sulfonate are sufficiently mixed,
Sieving, to which water-dispersible granules be made.
Embodiment 10（60% 2-cyano-3-amino-3-phenylancryic acetate Guardian wettable powder）
Active component 2-cyano-3-amino-3-phenylancryic acetate 10%
Active component Guardian 50%
The wooden sodium 3%
Amine carbonate 3%
White carbon 10%
Attapulgite surplus.
Preparation method：Above-mentioned substance is uniformly mixed, mixture is crushed through airslide disintegrating mill, and wettable powder is made.
Embodiment 11（12% 2-cyano-3-amino-3-phenylancryic acetate Guardian microcapsule suspending agent）
Active component 2-cyano-3-amino-3-phenylancryic acetate 2%
Active component Guardian 10%
Dimethylformamide 2%
Methyl diphenylene diisocyanate 3%
Fatty acid amide N methyl taurine sodium salt 2%
Hexamethylene diamine 0.5%
Gum arabic 2%
Polyvinyl alcohol 2%
Water polishing is to 100%
（1）2-cyano-3-amino-3-phenylancryic acetate and Guardian are dissolved in solvent, methyl diphenylene diisocyanate is added and is uniformly mixing to obtain
Oil phase；（2）Emulsifier is added in water, adjuvant is uniformly mixing to obtain water phase；（3）Water phase is added in oil phase, high speed homogenizing
Form oil-in-water emulsion；（4）Under 450 revs/min of speed conditions, ethylenediamine is added and participates in interface polymerization reaction, reaction temperature liter
To 55 DEG C, 3 hours solidification encystation are kept；（5）Dispersant, thickener is added, stirs evenly and microcapsule suspending agent is made.
Embodiment 12（24% 2-cyano-3-amino-3-phenylancryic acetate Guardian suspension seed-coating agent）
Active component 2-cyano-3-amino-3-phenylancryic acetate 4%
Active component Guardian 20%
NNO 3%
BY110 2%
APE-1 2%
Xanthans 0.15%
Propylene glycol 1%
Film forming agent 3%
Dyestuff 4%
Water surplus.
According to formula, by component（Except dyestuff, film forming agent）It weighs in proportion, ball mill ball milling is added 30 minutes, filtering,
It is pumped into dispersion tank high speed shear to be fully ground through sand mill after 3 minutes, control solid component particle diameter is ground within 2 microns
It is stirred evenly after mill, film forming agent and dyestuff is added to get suspension seed-coating agent product.
Control effect is tested：
The field efficiency test of bakanae disease and seedling seasonal febrile diseases carries out in Changfeng County hilllock market town experimental plot, test area 0.3hm2, often
Processing in triplicate, carries out spraying treatment or Cotton seeds at the initial stage of a disease, and preventive effect investigation, prevention knot are carried out after 15 days in dispenser
Fruit is shown in Table 5.The result shows that the bactericidal composition has good control effect to bakanae disease and seedling seasonal febrile diseases, in same dose or
It can reach higher control effect under relatively low dosage, and manage preventive effect everywhere in the bactericidal composition and be all higher than 89%, it is significantly high
In comparison medicament.
5 each embodiment of table prevents the crop field drug effect of bakanae disease and seedling seasonal febrile diseases
| Medicament | Dosage（g·ai/mu） | Bakanae disease preventive effect（%） | Seedling seasonal febrile diseases preventive effect（%） |
| Embodiment 1 | 4 | 97.14 | 91.24 |
| Embodiment 2 | 4 | 95.43 | 94.32 |
| Embodiment 3 | 4 | 95.15 | 91.25 |
| Embodiment 4 | 4 | 96.14 | 92.30 |
| Embodiment 5 | 4 | 91.24 | 93.24 |
| Embodiment 6 | Coating ratio 1：200 | 89.20 | 96.21 |
| Embodiment 7 | 4 | 91.36 | 92.35 |
| Embodiment 8 | 4 | 92.50 | 95.25 |
| Embodiment 9 | 4 | 94.12 | 93.33 |
| Embodiment 10 | 4 | 93.16 | 91.28 |
| Embodiment 11 | 4 | 95.23 | 89.36 |
| Embodiment 12 | Coating ratio 1：200 | 91.20 | 91.24 |
| 25% 2-cyano-3-amino-3-phenylancryic acetate SC | 4 | 71.23 | 23.14 |
| 20% fenhexamid SC | 4 | 56.48 | 71.24 |
| 15% Guardian SC | 4 | 54.12 | 64.53 |
Finally, it should also be noted that it is listed above be only the present invention several specific embodiments.Obviously, the present invention is not
Embodiment more than being limited to can also have many variations, for example be processed into ultra-low-volume formulation and make for hot mist machine and unmanned plane
With.All deformations that those skilled in the art directly can export or associate from present disclosure, think
It is the scope of protection of the invention.
Claims (3)
1. a kind of microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing, which is characterized in that the active component A of the microbicide compositions is cyanogen
Alkene bacterium ester, B are any one in fenhexamid or Guardian, and the mass ratio of A and B are 1：40 to 40:1.
2. the microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing according to claim 1, it is characterised in that：The microbicide compositions
Active component A be 2-cyano-3-amino-3-phenylancryic acetate, B is any one in fenhexamid or Guardian, and the mass ratio of A and B are 1：5 to 5:
1。
3. the microbicide compositions of 2-cyano-3-amino-3-phenylancryic acetate-containing according to claim 1, it is characterised in that：The microbicide compositions
Dosage form be suspending agent, missible oil, water dispersible granules, wettable powder, seed coat agent or microcapsule suspending agent.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810423328.2A CN108477168B (en) | 2018-05-06 | 2018-05-06 | Cyanoxastrobin-containing bactericide composition |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810423328.2A CN108477168B (en) | 2018-05-06 | 2018-05-06 | Cyanoxastrobin-containing bactericide composition |
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| CN108477168A true CN108477168A (en) | 2018-09-04 |
| CN108477168B CN108477168B (en) | 2020-12-15 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771502A (en) * | 2012-07-30 | 2012-11-14 | 陕西上格之路生物科学有限公司 | Sterilizing composition containing js399-19 and amide fungicide |
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2018
- 2018-05-06 CN CN201810423328.2A patent/CN108477168B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771502A (en) * | 2012-07-30 | 2012-11-14 | 陕西上格之路生物科学有限公司 | Sterilizing composition containing js399-19 and amide fungicide |
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| CN108477168B (en) | 2020-12-15 |
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