CN108465012A - A kind of Chinese medicine and its preparation method for treating bronchial asthma - Google Patents
A kind of Chinese medicine and its preparation method for treating bronchial asthma Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine for treating bronchial asthma, which is formulated by following medicinal material, their quality proportioning is:Chinese ephedra 6~10, asarum 3~6, gypsum 20~26, cassia twig 4~8, Exocarpium Citri Rubrum 10~12, lepidium seed 10~12, Radix Astragali 20~30, the root bark of white mulberry 20~30, Fructus Aurantii 10~14, root of Aucklandia lappa Decne 4~7, radix bupleuri 10~14, mulberry leaf 10~14, honeysuckle 10~14, tussilago 8~12, loguat leaf 8~12；The advance frying of the Chinese ephedra palpus, the gypsum life are used.Preparation method is by each taste Chinese medicine in formula for medicine, wherein Chinese ephedra was processed in advance；Above-mentioned whole drugs are dried again, is broken in blocks, disinfection adds water to decoct repeatedly 3 times, and medicinal extract is made in filtering；Fire drying in using again crushes, grind into powder；Finally be pressed into tablet or be packed into capsule to get.The Chinese Herbs of the present invention are rapid, reliable, safe to use, are suitable for treatment Bronchial Asthmas.
Description
Technical field
The present invention relates to pharmaceutical composition, in particular to the treatment bronchial asthma prepared using Chinese medicine as raw material
Drug.
Background technology
Bronchial asthma (abbreviation asthma) is a kind of common disease, frequently-occurring disease.Currently, about 300,000,000 people of global asthmatic patient, in
State's asthmatic patient about 30,000,000.Asthma is to influence the important diseases of people's physical and mental health.Treatment not in time, it is lack of standardization, asthma can
It can be fatal.In terms of the risk factor of asthma includes host factor (inherent cause) and environmental factor two, but most of heavy breathings
Asthma patient belongs to allergic constitution.The clinical manifestation of asthma is divided into acute attack stage, chronic sustained phase and clinical relieving period, acute
Breaking-out, may be fatal when giving treatment to not in time.Doctor trained in Western medicine is using control drug and the treatment of abirritant object.
China has accumulated abundant experience in terms for the treatment of bronchial asthma for thousands of years.In recent years, had many
Treat the Chinese medicine preparation application of bronchial asthma patent of invention, such as No. 200510114645.9《A kind of asthma for the treatment of
Compound Chinese medicinal preparation and preparation method thereof》, No. 200710116197.5《It is a kind of to take orally for treating in bronchial asthma
Medicine》, No. 200910231514.7《A kind of Chinese medicinal ointment for treating bronchial asthma》, No. 201010221755.6《A kind for the treatment of
The Chinese medicine composition of bronchial asthma》, No. 201110372302.8《A kind of Chinese medicine for treating bronchial asthma》、
201210409375.4 number《A kind of traditional Chinese herbal decoction and preparation method thereof for treating bronchial asthma》Deng.Above-mentioned patent application
The formula of part is different, and therapeutic effect is also not quite similar.In medical practice, in general, Chinese medicine is cured the disease, and effect is good, base
This is without side-effects.Therefore people continue to excavate Chinese material medicine resource, develop more efficiently drug.
Invention content
The purpose of the present invention, which is that, provides a kind of Chinese medicine for treating bronchial asthma, increases the medicine for the treatment of bronchial asthma
Article kind makes patient release the puzzlement of asthma, gets well.
It is a further object to provide the preparation methods of the Chinese medicine.
The Chinese medicine of the treatment bronchial asthma of the present invention is formulated by following medicinal material, their quality proportioning is:
Chinese ephedra 6~10, asarum 3~6, gypsum 20~26, cassia twig 4~8, Exocarpium Citri Rubrum 10~12, lepidium seed 10~12, Radix Astragali
20~30, the root bark of white mulberry 20~30, Fructus Aurantii 10~14, root of Aucklandia lappa Decne 4~7, radix bupleuri 10~14, mulberry leaf 10~14, honeysuckle 10~14,
Tussilago 8~12, loguat leaf 8~12；The advance frying of the Chinese ephedra palpus, the gypsum life are used.
The optimization formula of the Chinese medicine is：
Chinese ephedra 8, asarum 5, gypsum 22, cassia twig 6, Exocarpium Citri Rubrum 11, lepidium seed 11, Radix Astragali 25, the root bark of white mulberry 25, Fructus Aurantii 12, root of Aucklandia lappa Decne
6, radix bupleuri 12, mulberry leaf 12, honeysuckle 12, tussilago 10, loguat leaf 10；The advance frying of the Chinese ephedra palpus, the gypsum life are used.
In above-mentioned Chinese medicine, Chinese ephedra is the herbaceous stem stem of Ephedraceae plant ephedra sinica (Ephedra sinica), and acrid flavour is bitter, property
Temperature, energy sweating, relievings asthma, and Li Shui (see Jiangsu, compile by new medical college《Dictionary of medicinal plant》Page 2221)；Asarum is birthwort plant asarum
The whole herb with root of (Asarum sieboldii), acrid flavour is warm-natured, can wind-dispelling, cold dispelling, Hang Shui, have one's ideas straightened out (see《Dictionary of medicinal plant》
Page 1477)；Gypsum is the ore of Sulfates mineral gypsum (Cypsum), and acrid-sweet flavor is cold in nature, and expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst
(see《Dictionary of medicinal plant》Page 592)；Cassia twig is the spray of canella Chinese cassia tree (Cinnamomum cassia), acrid-sweet flavor, property
Temperature, energy sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi (see《Dictionary of medicinal plant》Page 1771)；Exocarpium Citri Rubrum is rutaceae tangerine produced in fujian province (Citrum
Tangerina) or the outer layer RED sector of Zhu's tangerine (Citrum erythrosa), acrid flavour is bitter, warm-natured, can dissolving phlegm, sharp gas is wide
In, dissipating bind (see《Dictionary of medicinal plant》Page 2639)；Lepidium seed is crucifer Lepidium apetalum (Lepidium apetalum)
Seed, acrid flavour is bitter, cold in nature, play the role of lower gas row water (see《Dictionary of medicinal plant》Page 2319)；Radix Astragali is legume astragalus
The root of (Astragalus membranaceus), sweet in flavor, slightly warm in nature, can beneficial stomach consolidate table, inducing diuresis for removing edema, tonifying middle-Jiao and Qi (see《In
Medicine voluminous dictionary》Page 2036)；The root bark of white mulberry is the root skin that moraceae plants mulberry (Morus alba) removes cork, sweet in flavor, cold in nature, has and rushes down
Lung is relievingd asthma, the effect of line water detumescence (see《Dictionary of medicinal plant》Page 1968)；Fructus Aurantii is rutaceae trifoliate orange (Poncirus
Trifoliata) nearly mellow fruit, it is cool in nature, it is bitterly, can relieving stagnant Qi, disperse accumulation (see《Dictionary of medicinal plant》Page 1507)；Root of Aucklandia lappa Decne
For the root of feverfew Aplotaxis auriculata (Saussurea lappa), acrid flavour is bitter, warm-natured, can promoting the circulation of qi, analgesic, warming middle-JIAO for easing the stomach (see《In
Medicine voluminous dictionary》Page 353)；Radix bupleuri is the root of samphire Bupleurum Chinese (Bupleurum chinense), and bitter is cool in nature, has
With in inducing diaphoresis, soothing the liver rising Yang effect (see《Chinese medicine voluminous dictionary》Page 1832)；Mulberry leaf are moraceae plants mulberry (Morus alba)
Leaf, it is bitter but sweet flavor, cold in nature, have expelling wind and clearing away heat, cooling blood for improving eyesight effect (see《Dictionary of medicinal plant》Page 1963)；Honeysuckle is Caprifoliaceae
The bud of plant honeysuckle (Lonicera japonica), it is sweet in flavor, it is cold in nature, can it is clearing heat and detoxicating (see《Dictionary of medicinal plant》1403
Page)；Tussilago is the bud of feverfew coltsfoot (Tussilago farfara), and acrid flavour is warm-natured, can moistening lung to lower qi, resolving sputum
Cough-relieving (see《Dictionary of medicinal plant》Page 2301)；Loguat leaf is the leaf of rosaceous plant loquat (Eriobotrya japonica),
Bitter, it is cool in nature, play the role of clearing lung-heat and stomach, lowering the adverse-rising QI to resolve phlegm (see《Dictionary of medicinal plant》Page 1248).
Above-mentioned medicinal material should meet《Chinese Pharmacopoeia》Regulation in nineteen ninety-five version one under each medicinal material item.
The preparation method of the Chinese medicine of the treatment bronchial asthma of the present invention is by each taste Chinese medicine in formula for medicine, wherein
Chinese ephedra was processed in advance；Again by above-mentioned whole drugs drying, broken in blocks, then with disinfection by ultraviolet light, it is put into pottery or copper tank or copper
Vessel (should not use iron pan) processed plus water decoct 3 times repeatedly, 1~2 hour for the first time, second 0.5~1 hour, third time 0.5
Hour, medicinal extract is made in filtering；Fire drying in using again crushes, is ground into 60 mesh powder；Last routinely pharmaceutical technology, is pressed into piece
Agent is packed into capsule, and every 1g or every 1g are to get tablet or capsule.Product should meet《Chinese Pharmacopoeia》Nineteen ninety-five version one
Requirement in portion.
The above-mentioned pharmaceutical technology for being pressed into tablet includes：1. 60 mesh powder obtained is added auxiliary material, main auxiliary material is glutinous
Mixture modified starch is uniformly mixed；2. in mixed powder plus water is as wetting agent, soft material is made；3. soft material was squeezed
Sieve, is made particle；4. particle by drying, makes, its is aqueous suitable and uniform, grain graininess is appropriate；5. dry particle through examine,
Confirm the requirement for meeting tablet；6. extruding tablet with Chong Yashi or rotary tablet machine, qualified as finished product is examined.
The pharmaceutical technology of above-mentioned capsule includes：1. preparing or buying the capsulae vacuus using gelatin as primary raw material；2. will system
The 60 mesh powder obtained cross No. 6 sieves, and obtained fine powder is spare；3. manually loading medicinal powder enters soft capsule, or is filled with automatic filling machine
Enter medicinal powder；4. the active ingredient and quality to medicinal powder are tested, sealed at capsule capping with the glue of gelatin after qualified,
Obtain finished product.
Inventor points out：This Chinese medicine can also be prepared into any type with conventional method of Chinese medicinal and often use peroral dosage form.
No matter which kind of dosage form, it is necessary to according to drug stock control relevant regulations store.
The usage of Chinese materia medica of the treatment bronchial asthma of the present invention is oral, warm water delivery service, 2 times a day, 4-5 each.
It can also take the circumstances into consideration plus-minus dose according to the state of an illness.
Result in clinical application shows that this Chinese Herbs is notable, take a few hours can cough-relieving, control asthma；Bronchitis is suffered from
Person, which has, makees special effect, and effective percentage is 85% or more
Inventor successfully cured many Bronchial Asthmas, wherein having than more typical case：
Case one：Certain is swum, female, 70 years old.Patient starts to suffer from bronchial asthma for 1975, for a long time with ephedrine Zhichuan, after by
Clenbuterol cough-relieving Zhichuan is just used in abusing and selling in state control ephedrine instead.Over nearly 5 years, since the age increases, gram asthma
Element has been difficult to solve bronchial asthma, and after being changed to take medicine of the present invention 1 month, asthma is substantially reduced, even served 4 months asthma
Basic control, body are obviously got well.
Case two：Mother the present inventor Zhu, female, 78 years old.Once suffered from bronchitis=asthma for many years, hormone is used for a long time
After medicine or Inophylline are alleviated, but medicine stops and break out.Started to take medicine of the present invention two months in 2006, asthma is substantially reduced, even
Half a year is taken, symptom controls completely.
Case three：Gong, man, 14 years old, Guizhou Province Bijie City people from the towns Cha He.It pants because patient often coughs, phlegm in pharynx
Ring, expiratory dyspnea, the bored pain of fullness sensation in chest is thirsty vexed, is bronchial asthma through hospital diagnosis.Drug of the present invention is taken after 5 days, is exhaled
It inhales smooth, even served 20 days, condition, follow-up after half a year is not recurred.
The Chinese medicine of the present invention, curative effect is rapid, reliable, safe to use, is suitable for treatment Bronchial Asthmas.
Specific implementation mode
Embodiment 1
By each taste Chinese medicine in formula for medicine, wherein Chinese ephedra was processed in advance；Above-mentioned whole drugs are dried again, are broken into
Piece, then with disinfection by ultraviolet light, be put into copper tank and water is added to decoct repeatedly 3 times, 2 hours for the first time, second 1 hour, third time 0.5
Hour, medicinal extract is made in filtering；Fire drying in using again crushes, is ground into 60 mesh powder；Last routinely pharmaceutical technology, is pressed into piece
Agent, every 1g is to get tablet.
Embodiment 2
Preparation process is the same as embodiment 1.It is ground into the drug powder of 60 mesh, finally routinely pharmaceutical technology, is packed into capsule,
Every 1g is to get capsule product.
Claims (3)
1. a kind of Chinese medicine for treating bronchial asthma, it is characterised in that the Chinese medicine is formulated by following medicinal material, they
Quality proportioning is:
Chinese ephedra 6~10, asarum 3~6, gypsum 20~26, cassia twig 4~8, Exocarpium Citri Rubrum 10~12, lepidium seed 10~12, Radix Astragali 20~
30, the root bark of white mulberry 20~30, Fructus Aurantii 10~14, root of Aucklandia lappa Decne 4~7, radix bupleuri 10~14, mulberry leaf 10~14, honeysuckle 10~14, tussilago
8~12, loguat leaf 8~12；The advance frying of the Chinese ephedra palpus, the gypsum life are used.
2. Chinese medicine described in accordance with the claim 1, it is characterised in that the Chinese medicine is formulated by following medicinal material, their matter
Amount matches:
Chinese ephedra 8, asarum 5, gypsum 22, cassia twig 6, Exocarpium Citri Rubrum 11, lepidium seed 11, Radix Astragali 25, the root bark of white mulberry 25, Fructus Aurantii 12, root of Aucklandia lappa Decne 6, bavin
Recklessly 12, mulberry leaf 12, honeysuckle 12, tussilago 10, loguat leaf 10；The advance frying of the Chinese ephedra palpus, the gypsum life are used.
3. the method for preparing one of claim 1 and 2 Chinese medicine, it is characterized in that by each taste Chinese medicine in formula for medicine, wherein
Chinese ephedra was processed in advance；Again by above-mentioned whole drugs drying, broken in blocks, then with disinfection by ultraviolet light, it is put into pottery or copper tank or copper
Vessel processed add water to decoct repeatedly 3 times, 1~2 hour for the first time, and second 0.5~1 hour, third time 0.5 hour, filtering was made
Medicinal extract；Fire drying in using again crushes, is ground into 60 mesh powder；Last routinely pharmaceutical technology is pressed into tablet or is packed into capsule,
Every 1g or every 1g are to get tablet or capsule.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810663573.0A CN108465012A (en) | 2018-06-25 | 2018-06-25 | A kind of Chinese medicine and its preparation method for treating bronchial asthma |
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|---|---|---|---|
| CN201810663573.0A CN108465012A (en) | 2018-06-25 | 2018-06-25 | A kind of Chinese medicine and its preparation method for treating bronchial asthma |
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ID=63259633
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| Country | Link |
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2018
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