CN108339093A - Chinese medicine composition and preparation method thereof for treating epileptics - Google Patents

Chinese medicine composition and preparation method thereof for treating epileptics Download PDF

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CN108339093A
CN108339093A CN201810481533.4A CN201810481533A CN108339093A CN 108339093 A CN108339093 A CN 108339093A CN 201810481533 A CN201810481533 A CN 201810481533A CN 108339093 A CN108339093 A CN 108339093A
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chinese medicine
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medicine composition
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幸永明
潘胜果
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Chongqing Yuelong Biological Pharmaceutical Co Ltd
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Chongqing Yuelong Biological Pharmaceutical Co Ltd
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Abstract

The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating epileptics.The raw material of Chinese medicine composition includes full worm, cinnabar, tabasheer, amber, earthworm, mother-of-pearl, alum, radix bupleuri, Rhizoma Gastrodiae, Radix Glycyrrhizae, centipede, Radix Curcumae, leech, Radix Rehmanniae, Radix Codonopsis, Radix Salviae Miltiorrhizae, method summer, zaocys dhumnade, cow-bezoar, the coptis, the dried immature fruit of citron orange, the shell of seaear and uncaria.Preparation method:Each raw material component is weighed in proportion, is crushed, is soaked after cleaning;Extraction is decocted later, is filtered and is collected filtrate;Filtrate is condensed into medicinal extract, obtains Chinese medicine composition.Chinese medicine composition of the present invention has excellent qi and activate blood circulation, tranquillizing the mind by relieving convulsion and activating collaterals and eliminating stagnation and other effects, there is confrontation function to various convulsions, the whole body that can significantly improve epileptic twitches, spits out white foams, general spasticity, two the symptoms such as turn over, significantly reduce frequency of disease development and morbidity duration, and safe without toxic side effect;In addition, Chinese medicine composition of the present invention is easy to use, there is good commercial promise.

Description

Chinese medicine composition and preparation method thereof for treating epileptics
Technical field
The present invention relates to field of Chinese herbal medicine technology, and in particular to a kind of Chinese medicine composition and its system for treating epileptics Preparation Method.
Background technology
Epilepsy, " epilepsy " or " epilepsy " being commonly called as are the electric discharges of cerebral neuron paroxysmal abnormality, are caused of short duration big A kind of chronic disease of brain disorder.It is shown according to Chinese cri dernier cri disease data, the overall illness rate of domestic epilepsy is 7.0 ‰, annual morbidity is that have the activity epilepsy illness rate of breaking-out in 28.8/10 ten thousand, 1 year be 4.6 ‰.Estimation is Chinese about accordingly There is 9,000,000 or so epileptic, wherein 500~6,000,000 be movable Patients with Epilepsy, while newly increasing epileptic about every year 400000, have become the second largest common disease that neurology department is only second to headache in Chinese epilepsy.
Such disease common sympton is shown as:The disturbance of consciousness for occurring suddenly and stopping suddenly, whole body twitch, mouth are spat white Foam, general spasticity, two turn over, such as ordinary person after revival.The reason of causing epilepsy is various, and common reason has with poisoning, lacks Oxygen, wound, infection, brain diseases, congenital disorders, metabolic disease, cardiovascular and cerebrovascular disease etc..Currently, the treatment of such disease Means are mostly based on western medicine, such as carbamazepine, epilepsy amine;Western medicine and medical practitioners have the excellent of it in terms of controlling epileptic attack Gesture, but too strong inhibiting effect can make cerebral nerve function by toxic side effect;It not only cannot thoroughly effect a radical cure epilepsy, be not achieved The purpose for the treatment of, and its side effect is big, drug dependence is strong, generates what mental depression, IQ, dysnoesia etc. can not avoid Side effect.
Based on this, study a kind of novel, safe without toxic side effect and can effectively, the treatment of safety or alleviate epileptics Drug have very important significance.
Invention content
For the defects in the prior art, the present invention is intended to provide it is a kind of for treat epileptics Chinese medicine composition and its Preparation method.Chinese medicine composition provided by the invention has excellent qi and activate blood circulation, tranquillizing the mind by relieving convulsion and activating collaterals and eliminating stagnation and other effects, Have confrontation function to various convulsions, the whole body that can significantly improve epileptic twitches, spits out white foams, general spasticity, two It the symptoms such as turns over, significantly reduces frequency of disease development and morbidity duration, and safe without toxic side effect;In addition, Chinese medicine provided by the invention Composition is easy to use, and cost is relatively low, has good commercial promise.
For this purpose, the present invention provides the following technical solutions:
In a first aspect, the present invention provide it is a kind of for treating the Chinese medicine composition of epileptics, raw material components by weight, Including:Complete 20~30 parts by weight of worm, 10~15 parts by weight of cinnabar, 10~20 parts by weight of tabasheer, 10~20 parts by weight of amber, Imperial 10~20 parts by weight, 10~15 parts by weight of mother-of-pearl, 20~30 parts by weight of radix bupleuri, 25~30 parts by weight of Radix Glycyrrhizae, centipede 10~ 20 parts by weight, 15~20 parts by weight of Radix Curcumae, 15~25 parts by weight of leech, 20~25 parts by weight of Radix Rehmanniae, 20~30 parts by weight of Radix Codonopsis, 25~30 parts by weight of Radix Salviae Miltiorrhizae, 20~25 parts by weight of method summer, 10~25 parts by weight of cow-bezoar, 15~25 parts by weight of the coptis, the shell of seaear 10 20~30 parts by weight of~15 parts by weight and uncaria.
Preferably, raw material components further include:20~30 parts by weight of Rhizoma Gastrodiae, 10~20 parts by weight of zaocys dhumnade, the dried immature fruit of citron orange 15~20 5~10 parts by weight of parts by weight and alum.
Preferably, Chinese medicine composition is made of following raw material components:25 parts by weight of full worm, 12 parts by weight of cinnabar, tabasheer 16 parts by weight, 15 parts by weight of amber, 15 parts by weight of earthworm, 12 parts by weight of mother-of-pearl, 8 parts by weight of alum, 25 parts by weight of radix bupleuri, day Numb 25 parts by weight, 30 parts by weight of Radix Glycyrrhizae, 15 parts by weight of centipede, 18 parts by weight of Radix Curcumae, 20 parts by weight of leech, 23 parts by weight of Radix Rehmanniae, 25 parts by weight of Radix Codonopsis, 26 parts by weight of Radix Salviae Miltiorrhizae, 22 parts by weight of method summer, 15 parts by weight of zaocys dhumnade, 10 parts by weight of cow-bezoar, 20 weight of the coptis Part, 25 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
Preferably, Chinese medicine composition is made of following raw material components:30 parts by weight of full worm, 10 parts by weight of cinnabar, tabasheer 20 parts by weight, 10 parts by weight of amber, 20 parts by weight of earthworm, 10 parts by weight of mother-of-pearl, 10 parts by weight of alum, 20 parts by weight of radix bupleuri, 30 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of Radix Glycyrrhizae, 20 parts by weight of centipede, 15 parts by weight of Radix Curcumae, 25 parts by weight of leech, 20 weight of Radix Rehmanniae Part, 30 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Salviae Miltiorrhizae, 25 parts by weight of method summer, 10 parts by weight of zaocys dhumnade, 25 parts by weight of cow-bezoar, the coptis 15 Parts by weight, 30 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
Second aspect, the present invention provide a kind of preparation method of Chinese medicine composition, include the following steps:S101:In proportion Each raw material component is weighed, crushes after cleaning, soaks later;S102:Boil the drug use after immersion by intense fire 5~ 15min, then exchange of notes fire heat 60~200min, filter and collect filtrate;S103:Relative density is when filtrate is condensed into 70 DEG C 1.10~1.20 medicinal extract, obtains Chinese medicine composition.
Preferably, in S101, the water of addition is 10~20 times of raw material components gross mass, soaking time be 10min~ 20min。
Preferably, in S101, each raw material component is crushed to 60~100 mesh.
It can pharmaceutically be connect it should be noted that Chinese medicine composition prepared by the above method can be further prepared into as needed The dosage form received.In addition, also belonging to protection scope of the present invention as drug made of active constituent using above-mentioned Chinese medicine composition.Pass through It by above-mentioned Chinese medicine composition, is prepared after directly preparing or being added pharmaceutically acceptable auxiliary material, can be made into and any pharmaceutically may be used The dosage form of receiving.Include by taking external preparation as an example:Solution, patch, vina, tincture, gelling agent, liniment, aerosol, spraying Agent, ointment, suppository and plastics.The drug of above-mentioned various dosage forms can be prepared according to the conventional method of pharmaceutical field. In clinical application, the dosage of Chinese medicine composition provided by the invention is generally each 2g, three times a day.
The third aspect, Chinese medicine composition provided by the invention is in preparing treatment epilepsy medicament and/or medicated premix Application.
The above technical solution of the present invention has the following advantages over the prior art:
(1) applicant has found by numerous studies:Chinese medicine composition provided by the invention has excellent qi and activate blood circulation, town Frightened tranquilizing the mind and activating collaterals and eliminating stagnation and other effects have confrontation function to various convulsions, and the whole body that can significantly improve epileptic is taken out Jerk, spit out white foams, general spasticity, two the symptoms such as turn over, significantly reduce frequency of disease development and morbidity duration, and safe and non-toxic secondary make With;In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has good commercial promise.
(2) preparation method provided by the invention is used, the same of each bulk pharmaceutical chemicals active constituent can retained to greatest extent When, the active ingredient in each raw medicinal material can be fully released, to make the Chinese medicine composition being finally prepared not Only there is good drug effect, and be easy to absorb, and then be rapidly achieved the purpose for improving epileptics.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description Obviously, or practice through the invention is recognized.
Specific implementation mode
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer Illustrate technical scheme of the present invention, therefore be only used as example, and not intended to limit the protection scope of the present invention.
Experimental method in following embodiments is unless otherwise specified conventional method.
Test material as used in the following examples is unless otherwise specified to be commercially available from conventional reagent shop.
Quantitative test in following embodiment, is respectively provided with three repeated experiments, and data are the average value of three repeated experiments Or mean+SD.
It is full worm as used in the following examples, cinnabar, tabasheer, amber, earthworm, mother-of-pearl, alum, radix bupleuri, Rhizoma Gastrodiae, sweet Grass, centipede, Radix Curcumae, leech, Radix Rehmanniae, Radix Codonopsis, Radix Salviae Miltiorrhizae, method summer, zaocys dhumnade, cow-bezoar, the coptis, the dried immature fruit of citron orange, the shell of seaear and uncaria accord with Close the pertinent regulations under Chinese Pharmacopoeia (version in 2017) each medicinal material item of text.Before feeding intake, by identification, ingredients is in kind It is consistent with title, quality complies with standard.
The present invention provides a kind of Chinese medicine composition for treating epileptics, which is characterized in that raw material components are by weight Meter, including:20~30 parts by weight of full worm, 10~15 parts by weight of cinnabar, 10~20 parts by weight of tabasheer, 10~20 weight of amber Part, 10~20 parts by weight of earthworm, 10~15 parts by weight of mother-of-pearl, 20~30 parts by weight of radix bupleuri, 25~30 parts by weight of Radix Glycyrrhizae, centipede 10~20 parts by weight, 15~20 parts by weight of Radix Curcumae, 15~25 parts by weight of leech, 20~25 parts by weight of Radix Rehmanniae, 20~30 weight of Radix Codonopsis Measure part, 25~30 parts by weight of Radix Salviae Miltiorrhizae, 20~25 parts by weight of method summer, 10~25 parts by weight of cow-bezoar, 15~25 parts by weight of the coptis, Shi Jue 20~30 parts by weight of bright 10~15 parts by weight and uncaria;And raw material components preferably further include 20~30 parts by weight of Rhizoma Gastrodiae, zaocys dhumnade 5~10 parts by weight of 10~20 parts by weight, 15~20 parts by weight of the dried immature fruit of citron orange and alum.
In addition, for the Chinese medicine composition of the present invention, the present invention specially devises preparation method, includes the following steps:
S101:Weigh each raw material component in proportion, clean after be crushed to 60~100 mesh, soak later 10min~ 20min;Wherein, the water of addition is 10~20 times of raw material components gross mass.
S102:Boil the drug use after immersion by intense fire 5~15min, then exchange of notes fire heats 60~200min, filtering is simultaneously Collect filtrate.
S103:The medicinal extract that relative density is 1.10~1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
It illustrates With reference to embodiment:
Embodiment one
The present embodiment provides a kind of Chinese medicine compositions for treating epileptics, are prepared by following raw material components:Entirely 25 parts by weight of worm, 12 parts by weight of cinnabar, 16 parts by weight of tabasheer, 15 parts by weight of amber, 15 parts by weight of earthworm, 12 weight of mother-of-pearl Part, 8 parts by weight of alum, 25 parts by weight of radix bupleuri, 25 parts by weight of Rhizoma Gastrodiae, 30 parts by weight of Radix Glycyrrhizae, 15 parts by weight of centipede, 18 weight of Radix Curcumae Part, 20 parts by weight of leech, 23 parts by weight of Radix Rehmanniae, 25 parts by weight of Radix Codonopsis, 26 parts by weight of Radix Salviae Miltiorrhizae, 22 parts by weight of method summer, zaocys dhumnade 15 Parts by weight, 10 parts by weight of cow-bezoar, 20 parts by weight of the coptis, 25 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition:
S101:Each raw material component is weighed in proportion, is crushed to 100 mesh after cleaning, is soaked 10min later;Wherein, add The water entered is 20 times of raw material components gross mass.
S102:Boil the drug use after immersion by intense fire 5min, then exchange of notes fire heats 200min, filters and collects filter Liquid.
S103:The medicinal extract that relative density is 1.10 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment two
The present embodiment provides a kind of Chinese medicine compositions for treating epileptics, are prepared by following raw material components:Entirely 30 parts by weight of worm, 10 parts by weight of cinnabar, 20 parts by weight of tabasheer, 10 parts by weight of amber, 20 parts by weight of earthworm, 10 weight of mother-of-pearl Part, 10 parts by weight of alum, 20 parts by weight of radix bupleuri, 30 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of Radix Glycyrrhizae, 20 parts by weight of centipede, 15 weight of Radix Curcumae Measure part, 25 parts by weight of leech, 20 parts by weight of Radix Rehmanniae, 30 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Salviae Miltiorrhizae, 25 parts by weight of method summer, zaocys dhumnade 10 parts by weight, 25 parts by weight of cow-bezoar, 15 parts by weight of the coptis, 30 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition:
S101:Each raw material component is weighed in proportion, is crushed to 60 mesh after cleaning, is soaked 20min later;Wherein, add The water entered is 10 times of raw material components gross mass.
S102:Boil the drug use after immersion by intense fire 15min, then exchange of notes fire heats 60min, filters and collects filter Liquid.
S103:The medicinal extract that relative density is 1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Embodiment three
The present embodiment provides a kind of Chinese medicine compositions for treating epileptics, are prepared by following raw material components:Entirely 25 parts by weight of worm, 12 parts by weight of cinnabar, 16 parts by weight of tabasheer, 15 parts by weight of amber, 15 parts by weight of earthworm, 12 weight of mother-of-pearl Part, 8 parts by weight of alum, 25 parts by weight of radix bupleuri, 25 parts by weight of Rhizoma Gastrodiae, 30 parts by weight of Radix Glycyrrhizae, 15 parts by weight of centipede, 18 weight of Radix Curcumae Part, 20 parts by weight of leech, 23 parts by weight of Radix Rehmanniae, 25 parts by weight of Radix Codonopsis, 26 parts by weight of Radix Salviae Miltiorrhizae, 22 parts by weight of method summer, zaocys dhumnade 15 Parts by weight, 10 parts by weight of cow-bezoar, 20 parts by weight of the coptis, 25 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition:
S101:Each raw material component is weighed in proportion, is crushed to 100 mesh after cleaning, is soaked 10min later;Wherein, add The water entered is 20 times of raw material components gross mass.
S102:Boil the drug use after immersion by intense fire 5min, then exchange of notes fire heats 200min, filters and collects filter Liquid.
S103:The medicinal extract that relative density is 1.10 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
Example IV
The present embodiment provides a kind of Chinese medicine compositions for treating epileptics, are prepared by following raw material components:Entirely 30 parts by weight of worm, 10 parts by weight of cinnabar, 20 parts by weight of tabasheer, 10 parts by weight of amber, 20 parts by weight of earthworm, 10 weight of mother-of-pearl Part, 10 parts by weight of alum, 20 parts by weight of radix bupleuri, 30 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of Radix Glycyrrhizae, 20 parts by weight of centipede, 15 weight of Radix Curcumae Measure part, 25 parts by weight of leech, 20 parts by weight of Radix Rehmanniae, 30 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Salviae Miltiorrhizae, 25 parts by weight of method summer, zaocys dhumnade 10 parts by weight, 25 parts by weight of cow-bezoar, 15 parts by weight of the coptis, 30 parts by weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition:
S101:Each raw material component is weighed in proportion, is crushed to 60 mesh after cleaning, is soaked 20min later;Wherein, add The water entered is 10 times of raw material components gross mass.
S102:Boil the drug use after immersion by intense fire 15min, then exchange of notes fire heats 60min, filters and collects filter Liquid.
S103:The medicinal extract that relative density is 1.20 when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.
In addition, the effect of in order to preferably evaluate each embodiment, carry out following experiment:
One, toxicity test
It is the small white mouse 80 (each 40 of male and female) of 18~22g to select weight, is divided into 4 groups, takes implementation of the present invention respectively The Chinese medicine composition that example one to example IV is prepared.Specifically, the Chinese medicine composition 8g for taking the present invention, adds deionized water system At concentrate 20mL, every small white mouse gives concentrate 1.2mL gavages, twice daily;Observation 30 days, small white mouse health are raw It deposits, it is without any side effects;Blood picture, liver function, each organs and tissues state, the indifference compared with normal small white mouse is dissected and observed. It is demonstrated experimentally that Chinese medicine composition provided by the invention is nontoxic.
Two, clinical test
All kinds of epileptics 400 are collected, each patient is accompanied by different degrees of whole body and twitches, spits out white foams, entirely Body spasm, two the symptoms such as turn over, and illness frequency be up to 2 days it is primary.Specifically, patient is divided into 4 groups, every group 100, The embodiment of the present invention one is taken respectively to the Chinese medicine composition 5 weeks of example IV, 2 times a day, every time by first group to the 4th group 3g;Curative effect is observed later, and measures the diminution degree of each patient's epileptics volume, it is specific as shown in table 1.
Curative effect is judged as:
It is effective:Compared with the intermittent time of breaking out before treatment, extends 1 year or more and do not send out author;It improves:Breaking-out completely control or Seizure frequency reduces 60% or more, and disease time shortens every time, and symptom mitigates;It is poor:Seizure frequency reduces 60% or less.Its In, total effective rate=obvious effective rate+improvement rate.
1 each embodiment patient epileptics symptom situation of change statistical form of table
Case number of cases/name Effective/name Improvement/name In vain/name Total effective rate/%
Embodiment one 100 50 45 5 95
Embodiment two 100 55 42 3 97
Embodiment three 100 76 23 1 99
Example IV 100 70 28 2 98
Certainly, the case where being enumerated in addition to embodiment one to example IV, the type and weight percent of other raw material components, Condition and parameter in preparation process etc. are also possible.It should be noted that each patient does not occur not over the course for the treatment of Suitable symptom.
Chinese medicine composition provided by the invention has excellent qi and activate blood circulation, tranquillizing the mind by relieving convulsion and activating collaterals and eliminating stagnation and other effects, Have confrontation function to various convulsions, the whole body that can significantly improve epileptic twitches, spits out white foams, general spasticity, two It the symptoms such as turns over, significantly reduces frequency of disease development and morbidity duration, and safe without toxic side effect;In addition, Chinese medicine provided by the invention Composition is easy to use, and cost is relatively low, has good commercial promise.
In the description of this specification, it is to be understood that reference term " one embodiment ", " is shown " some embodiments " The description of example ", " specific example " or " some examples " etc. mean specific features described in conjunction with this embodiment or example, structure, Material or feature are included at least one embodiment or example of the invention.In the present specification, above-mentioned term is shown The statement of meaning property is necessarily directed to identical embodiment or example.Moreover, specific features, structure, material or the spy of description Point may be combined in any suitable manner in any one or more of the embodiments or examples.In addition, without conflicting with each other, Those skilled in the art can be by different embodiments or examples described in this specification and different embodiments or examples Feature is combined.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned Embodiment is changed, changes, replacing and modification.

Claims (8)

1. a kind of for treating the Chinese medicine composition of epileptics, which is characterized in that raw material components by weight, including:
Complete 20~30 parts by weight of worm, 10~15 parts by weight of cinnabar, 10~20 parts by weight of tabasheer, 10~20 parts by weight of amber, Imperial 10~20 parts by weight, 10~15 parts by weight of mother-of-pearl, 20~30 parts by weight of radix bupleuri, 25~30 parts by weight of Radix Glycyrrhizae, centipede 10~ 20 parts by weight, 15~20 parts by weight of Radix Curcumae, 15~25 parts by weight of leech, 20~25 parts by weight of Radix Rehmanniae, 20~30 parts by weight of Radix Codonopsis, 25~30 parts by weight of Radix Salviae Miltiorrhizae, 20~25 parts by weight of method summer, 10~25 parts by weight of cow-bezoar, 15~25 parts by weight of the coptis, the shell of seaear 10 20~30 parts by weight of~15 parts by weight and uncaria.
2. the Chinese medicine composition according to claim 1 for treating epileptics, which is characterized in that further include:
20~30 parts by weight of Rhizoma Gastrodiae, 5~10 parts by weight of 10~20 parts by weight of zaocys dhumnade, 15~20 parts by weight of the dried immature fruit of citron orange and alum.
3. the Chinese medicine composition according to claim 2 for treating epileptics, which is characterized in that by following raw material components It is made:
25 parts by weight of full worm, 12 parts by weight of cinnabar, 16 parts by weight of tabasheer, 15 parts by weight of amber, 15 parts by weight of earthworm, mother-of-pearl 12 parts by weight, 8 parts by weight of alum, 25 parts by weight of radix bupleuri, 25 parts by weight of Rhizoma Gastrodiae, 30 parts by weight of Radix Glycyrrhizae, 15 parts by weight of centipede, Radix Curcumae 18 parts by weight, 20 parts by weight of leech, 23 parts by weight of Radix Rehmanniae, 25 parts by weight of Radix Codonopsis, 26 parts by weight of Radix Salviae Miltiorrhizae, 22 parts by weight of method summer, crow 15 parts by weight of tip snake, 10 parts by weight of cow-bezoar, 20 parts by weight of the coptis, 25 weight of 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria Measure part.
4. the Chinese medicine composition according to claim 2 for treating epileptics, which is characterized in that by following raw material components It is made:
30 parts by weight of full worm, 10 parts by weight of cinnabar, 20 parts by weight of tabasheer, 10 parts by weight of amber, 20 parts by weight of earthworm, mother-of-pearl It is 10 parts by weight, 10 parts by weight of alum, 20 parts by weight of radix bupleuri, 30 parts by weight of Rhizoma Gastrodiae, 25 parts by weight of Radix Glycyrrhizae, 20 parts by weight of centipede, strongly fragrant Golden 15 parts by weight, 25 parts by weight of leech, 20 parts by weight of Radix Rehmanniae, 30 parts by weight of Radix Codonopsis, 25 parts by weight of Radix Salviae Miltiorrhizae, 25 parts by weight of method summer, 10 parts by weight of zaocys dhumnade, 25 parts by weight of cow-bezoar, 15 parts by weight of the coptis, 20 parts by weight of the dried immature fruit of citron orange, 10 parts by weight of the shell of seaear and uncaria 30 Parts by weight.
5. the preparation method of Claims 1 to 4 any one of them Chinese medicine composition, which is characterized in that include the following steps:
S101:Each raw material component is weighed in proportion, is crushed after cleaning, is soaked later;
S102:Boil the drug use after the immersion by intense fire 5~15min, then exchange of notes fire heats 60~200min, filtering is simultaneously Collect filtrate;
S103:The medicinal extract that relative density is 1.10~1.20 when the filtrate is condensed into 70 DEG C, obtains the Chinese medicine composition.
6. the preparation method of the Chinese medicine composition described in claim 5, it is characterised in that:
In the S101, the water of addition is 10~20 times of the raw material components gross mass, soaking time be 10min~ 20min。
7. the preparation method of the Chinese medicine composition described in claim 6, it is characterised in that:
In the S101, each raw material component is crushed to 60~100 mesh.
8. Claims 1 to 4 any one of them Chinese medicine composition is in preparing treatment epilepsy medicament and/or medicated premix Application.
CN201810481533.4A 2018-05-18 2018-05-18 Chinese medicine composition and preparation method thereof for treating epileptics Pending CN108339093A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5888318A (en) * 1981-11-21 1983-05-26 Moriyasu Kino Natural total mineral agent
CN1138465A (en) * 1995-06-16 1996-12-25 姜春水 Medicine for treatment of epilepsy
CN1179321A (en) * 1997-10-28 1998-04-22 董国良 Epilepsy recovering pill and preparing process thereof
CN1954876A (en) * 2006-10-11 2007-05-02 刘光跃 Traditional Chinese medicine for treating epilepsy disease
CN101559195A (en) * 2008-04-16 2009-10-21 苗卫萍 Epilepsy therapy capsule and preparation method thereof
CN104208652A (en) * 2014-10-09 2014-12-17 马俊安 Traditional Chinese medicine for treating epilepsy and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5888318A (en) * 1981-11-21 1983-05-26 Moriyasu Kino Natural total mineral agent
CN1138465A (en) * 1995-06-16 1996-12-25 姜春水 Medicine for treatment of epilepsy
CN1179321A (en) * 1997-10-28 1998-04-22 董国良 Epilepsy recovering pill and preparing process thereof
CN1954876A (en) * 2006-10-11 2007-05-02 刘光跃 Traditional Chinese medicine for treating epilepsy disease
CN101559195A (en) * 2008-04-16 2009-10-21 苗卫萍 Epilepsy therapy capsule and preparation method thereof
CN104208652A (en) * 2014-10-09 2014-12-17 马俊安 Traditional Chinese medicine for treating epilepsy and preparation method thereof

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Application publication date: 20180731