CN1082958C - 他唑非隆的另一结晶形态 - Google Patents

他唑非隆的另一结晶形态 Download PDF

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Publication number
CN1082958C
CN1082958C CN96197822A CN96197822A CN1082958C CN 1082958 C CN1082958 C CN 1082958C CN 96197822 A CN96197822 A CN 96197822A CN 96197822 A CN96197822 A CN 96197822A CN 1082958 C CN1082958 C CN 1082958C
Authority
CN
China
Prior art keywords
type
hydroxyphenyl
bis
dimethylethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN96197822A
Other languages
English (en)
Chinese (zh)
Other versions
CN1200730A (zh
Inventor
M·M·汉森
A·R·哈内斯
S·M·雷乌泽尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of CN1200730A publication Critical patent/CN1200730A/zh
Application granted granted Critical
Publication of CN1082958C publication Critical patent/CN1082958C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
CN96197822A 1995-09-07 1996-09-03 他唑非隆的另一结晶形态 Expired - Fee Related CN1082958C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US335695P 1995-09-07 1995-09-07
US60/003,356 1995-09-07

Publications (2)

Publication Number Publication Date
CN1200730A CN1200730A (zh) 1998-12-02
CN1082958C true CN1082958C (zh) 2002-04-17

Family

ID=21705475

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96197822A Expired - Fee Related CN1082958C (zh) 1995-09-07 1996-09-03 他唑非隆的另一结晶形态

Country Status (29)

Country Link
EP (1) EP0761656B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH11514978A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR19990044453A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1082958C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (2) AR003484A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE198476T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU716684B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9610201A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2231132A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CO (1) CO4750653A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ68098A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69611407T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0761656T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EA (1) EA000258B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2153081T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3035656T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HUP9901458A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN182320B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY132351A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO309719B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ316810A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PE (1) PE23298A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL325602A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT761656E (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (1) SI0761656T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TR (1) TR199800398T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW460471B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1997009320A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA967422B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US538690A (en) * 1895-05-07 Automatic watering-trough for animals

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216002A (en) * 1989-12-21 1993-06-01 Eli Lilly And Company Method of treating inflammatory bowel disease
IL96654A (en) * 1989-12-21 1995-06-29 Lilly Co Eli Hydroxybenzyl substituted sulfur containing heterocyclic derivatives their preparation and pharmaceutical compositions containing them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US538690A (en) * 1895-05-07 Automatic watering-trough for animals

Also Published As

Publication number Publication date
IN182320B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1999-03-20
JPH11514978A (ja) 1999-12-21
PT761656E (pt) 2001-04-30
BR9610201A (pt) 1998-08-11
AR003483A1 (es) 1998-08-05
CA2231132A1 (en) 1997-03-13
DE69611407D1 (de) 2001-02-08
AU6912796A (en) 1997-03-27
NO980913L (no) 1998-03-03
MX9801705A (es) 1998-05-31
AU716684B2 (en) 2000-03-02
EA199800275A1 (ru) 1998-08-27
ATE198476T1 (de) 2001-01-15
NO309719B1 (no) 2001-03-19
AR003484A1 (es) 1998-08-05
MY132351A (en) 2007-10-31
ES2153081T3 (es) 2001-02-16
NZ316810A (en) 1999-07-29
EP0761656A1 (en) 1997-03-12
ZA967422B (en) 1998-03-02
PE23298A1 (es) 1998-05-05
TW460471B (en) 2001-10-21
EP0761656B1 (en) 2001-01-03
HUP9901458A3 (en) 2000-05-29
TR199800398T1 (xx) 1998-05-21
NO980913D0 (no) 1998-03-03
KR19990044453A (ko) 1999-06-25
DE69611407T2 (de) 2001-06-13
SI0761656T1 (en) 2001-06-30
CO4750653A1 (es) 1999-03-31
CN1200730A (zh) 1998-12-02
PL325602A1 (en) 1998-08-03
HUP9901458A2 (hu) 1999-09-28
EA000258B1 (ru) 1999-02-25
GR3035656T3 (en) 2001-06-29
CZ68098A3 (cs) 1998-08-12
WO1997009320A1 (en) 1997-03-13
DK0761656T3 (da) 2001-02-05

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