CN108236665A - A kind of Chinese medicinal formulae for treating depression - Google Patents

A kind of Chinese medicinal formulae for treating depression Download PDF

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CN108236665A
CN108236665A CN201611271494.2A CN201611271494A CN108236665A CN 108236665 A CN108236665 A CN 108236665A CN 201611271494 A CN201611271494 A CN 201611271494A CN 108236665 A CN108236665 A CN 108236665A
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depression
chinese medicinal
medicinal formulae
radix
treating depression
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邢德忠
邢德芳
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/69—Polygalaceae (Milkwort family)
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    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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    • A61K36/79—Schisandraceae (Schisandra family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern

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Abstract

A kind of Chinese medicinal formulae for treating depression, it is characterised in that be made of the bulk pharmaceutical chemicals of following weight：10 60g of the coptis, 0.1 0.3g of cinnabar, jujube kernel 10g 40g, asparagus fern 10g 30g, calamus 25g 40g, amber 20g 35g, earthworm 25g 35g, radix bupleuri 25g 35g, Rhizoma Chuanxiong 15g 28g, Poria cocos 18g 30g, Radix Polygalae 25g, thizoma curculiginis 5g 15g, Radix Angelicae Sinensis 15g 25g, Schisandra chinensis 20g 40g, campanulaceae 15g 25g.This kind treats the Chinese medicinal formulae of depression, for depression is curative for effect, toxic side effect is small, bulk pharmaceutical chemicals derive from a wealth of sources, treatment cost is low, cure rate is high and uneasy to recur.

Description

A kind of Chinese medicinal formulae for treating depression
Technical field
The present invention relates to a kind of Chinese medicinal formulaes for treating depression, belong to the field of Chinese medicines.
Background technology
Depression belongs to a kind of common mental disorder of mankind, and depression is clinically low with notable and lasting mental state Fall, the decline of retardation of thinking, bulesis, Cognitive function damage, somatization etc. are main feature, and mental state it is low with situation not Match, clinical manifestation wild or even can occur numb from depressed to sad；Often with anxiety symptom；Severe patient may occur in which The psychotic symptoms such as illusion, vain hope.Depression is a kind of high morbidity, the mental disorder that height is disabled, height recurs.State Inner is investigated Data shows that depression is suffered from China as many as 90,000,000 people, and illness rate accounts for 15% of total population or so, the homicide rate ratio of depression Population is 20 times high.According to the data in the U.S., there are about 11,000,000 people every year in the U.S. to suffer from clinical depression, clinical depression patient Homicide rate for 10-15%, be affected by this, 20,000,000,000 dollars about lost every year in the U.S..By more depressed to human health than visible Prestige association it is very big.There is scholarly forecast, it will be as being only second to the second disability-causing factor of the mankind of cancer to the year two thousand twenty depression.
The drug therapy of depression, clinically the depression treatment of a line takes Western medicine drug mainly to include choosing at present Selecting property serotonin takes the photograph inhibitor again, and (SSRI represents agents fluoxetine, Paxil, Sertraline, Fluvoxamine, Citalopram And escitalopram), (SNRI represents drug Venlafaxine and degree for serotonin and norepinephrine reuptake inhibitors Duloxetine), norepinephrine and the spy's property led serotonin energy antidepressants (NaSSA represents drug Mirtazapine) etc..This this west Medicine class treatment depression can receive effective therapeutic effect, but there are side effect is big, treatment cost is high and the problems such as high recurrence rate.
Invention content
The present invention seeks to be to overcome the shortcomings of that the prior art treats depressive illness, provide and a kind of treat depression The Chinese medicinal formulae of disease, to realize for depression is curative for effect, toxic side effect is small, bulk pharmaceutical chemicals derive from a wealth of sources, treatment cost is low, controls More rate height and purpose uneasy to recur.
Purpose to realize the present invention, the technical solution used in the present invention are：A kind of Chinese medicine for treating depression is provided Prescription, it is characterised in that be made of the bulk pharmaceutical chemicals of following weight：Coptis 10-60g, cinnabar 0.1-0.3g, jujube kernel 10g-40g, day Winter 10g-30g, calamus 25g-40g, amber 20g-35g, earthworm 25g-35g, radix bupleuri 25g-35g, Rhizoma Chuanxiong 15g-28g, Poria cocos 18g-30g, Radix Polygalae 25g, thizoma curculiginis 5g-15g, Radix Angelicae Sinensis 15g-25g, Schisandra chinensis 20g-40g, campanulaceae 15g-25g.
The preferred technical solution of the present invention is：A kind of Chinese medicinal formulae for treating depression, it is characterised in that by following weight Bulk pharmaceutical chemicals composition：Coptis 50g, cinnabar 0.15g, jujube kernel 30g, asparagus fern 20g, calamus 35g, amber 30g, earthworm 30g, radix bupleuri 30g, Rhizoma Chuanxiong 20g, Fu luxuriant growth 25g, Radix Polygalae 25g, thizoma curculiginis 10g, Radix Angelicae Sinensis 20g, Schisandra chinensis 30g.Campanulaceae 20g.
Medicament prepares and instructions of taking：By a kind of Chinese medicinal formulae for treating depression of the present invention, by the cinnabar list of its prescription Only weighing is simultaneously ground into as Fine ends individually packaging, then weighing is placed in mixing in decocting medicine pot respectively by other all medicines in its prescription, It adds in 3 times of warm water of Chinese medicine total amount to impregnate 10 minutes, then heating decocts 50 minutes, filters to obtain first time liquid；The dregs of a decoction are added 2 again Times decocting is endured 40 minutes, filters to obtain second of liquid；The dregs of a decoction are added to 2 times of water again again, then are decocted 30 minutes, filter to obtain third time medicine Liquid；It liquid merging will stir well three times, respectively in early, middle and late one after each meal, cinnabar does not divide three equal parts carefully, and point early, middle and late clothes are originally Warm water is taken before prescription liquid；This Chinese medicinal formulae one dose per day continuously takes 21 days as a treatment course.
Pharmacological action：
The coptis：Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation, rush down dysentery, jaundice, unconsciousness due to high fever, internal heat are vomitted High Sheng, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis；Eczema, wet sore are controlled outside, duct is suppurated.Prepared RHIZOMA COPTIDIS with vino It is burning hot to be apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach anti-vomiting.It is mutually tied for fever and chills, damp and hot middle resistance, feeling of fullness vomiting. Cornel coptis is relaxed liver anti-vomiting.For liver-stomach disharmony, acid regurgitation is vomitted.
Cinnabar：It is sweet, it is slightly cold.It is toxic.Thoughts of returning home warp.Tranquilizing mind.It is not normal to control the confused and worried or mind, sees palpitaition, has a sleepless night, it is mad Hot-tempered and epilepsy etc.；Sore swollen toxin, pharynx swelling, aphthae are controlled in external application.
Jujube kernel：Antitoxic heart-soothing and sedative；Nourishing the liver；Arrest sweating.Restlessness of asrhenia type and insomnia；Palpitation with fear palpitation；Physically weak spontaneous perspiration, night sweat.
Asparagus fern：Nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid.For dryness of the lung dry cough, pertussis phlegm sticks, soreness of waist and knee joint, osteopyrexia and fever, and interior heat disappears Yearningly, pyreticosis Tianjin is hindered, dry throat and mouth, dry constipation of intestines.
Calamus：It is bitter, acrid in flavour and warm in nature.Resolving sputum is had one's ideas straightened out, invigorating the spleen, dampness removing.For epilepsy, palpitation with fear is forgetful, clouded in mind, humidity hysteresis ruffian It is swollen, dysentery, rheumatalgia pain, carbuncle swells scabies.
Amber：Tranquillizing the mind by relieving convulsion；Dissipate stasis of blood hemostasis；Promoting diuresis for stranguria；Go screen improving eyesight.Main insomnia of palpitating with fear；Infantile convulsion epilepsy；Blood strangury blood Urine；Amenorrhea due to stagnation of blood；Postpartum stasis of blood；A lump in the abdomen causing distension and pain；Mesh life is hidden from view；Carbuncle sore tumefacting virus.For infantile convulsion, epilepsy, palpitaition is had a sleepless night, Difficult urination, odynuria, hematuria, amenorrhoea.
Earthworm：Clearing heat for calming endogenous wind, clearing and activating the channels and collaterals, clearing lung, relieving asthma, reducing fever and causing diuresis, for high fever frightened epilepsy, demented.Bi Zheng and half body It is unsuccessful.Lung heat asthma.Bladder heat stagnation, difficult urination or renal shutdown are obstructed.
Radix bupleuri：In inducing diaphoresis, soothing liver-qi stagnation, yang invigorating, preventing malaria of bringing down a fever.For cold, fever, fevers and chills alternate, chest side of body is swollen Bitterly, irregular menstruation, the prolapse of uterus, rectal prolapse.
Rhizoma Chuanxiong：Acrid flavour, warm-natured, Return liver, courage, the heart channel of Hang-Shaoyin, gas perfume (or spice), which rises, to be dissipated.For irregular menstruation, dysmenorrhoea, Amenorrhea, difficult labour, afterbirth Under not, lochia abdominal pain, lump, heart pain in chest and hypochondrium, traumatic injury swelling and pain, dizziness of having a headache mesh is dark, wind-cold-dampness arthralgia, limbs fiber crops Wood, ulcer sores.
Poria cocos：Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind Uneasiness, insomnia of palpitating with fear.
Radix Polygalae：Tranquilize the mind and promote the intelligence, Xie Yu.Control palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, ulcer sore swells.
Thizoma curculiginis：Warming kidney and enhancing body；Dispel cold-dampness.Main impotence cold sperm, aconuresis, coldness and pain in the epigastrium, soreness of waist and knee joint, muscles and bones are soft Weak, lower limb contraction, climacteric syndrome.
Radix Angelicae Sinensis：It is sweet, pungent, warm.It enriches blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Bitterly Through；Abdominal mass knot gathers；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Schisandra chinensis：It astringes the lung, nourshing kidney is promoted the production of body fluid, and receives sweat, puckery essence.It breathes with cough for treating the deficiency syndrome of the lung, thirst, spontaneous perspiration, night sweat, Internal lesion caused by overexertion is thin thin, emission, protracted dysentery and diarrhea.
Campanulaceae：Facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, chest distress, pharyngalgia hoarse voice, lung carbuncle pyemesis.
In the Chinese medicinal formulae of the present invention coptis and radix bupleuri have clearing heat and detoxicating, the strongly fragrant liver knot that relaxes, sternal rib turgor and fever coma it Effect；Calamus, Radix Polygalae and amber have tranquilizing the mind benefit to know, insomnia forgetfulness, dissipating phlegm for resuscitation, tranquillizing the mind by relieving convulsion and palpitation with fear；Rhizoma Chuanxiong, dragon and Thizoma curculiginis have costalgia of chest, head dazzle the eyes dark, extremity numbness, the active frightened epilepsy of clearing heat for calming endogenous wind dredging collateral, warming and invigorating kidney Yang and dispelling cold soreness and weakness of waist and knees it Effect；Schisandra chinensis and asparagus fern are astringed the lung the nourshing kidney cough-relieving convergence nourishing yin to moisten dryness and the effect of soreness of waist and knee joint of promoting the production of body fluid；Poria cocos and campanulaceae have The effect of confused and worried, palpitation with fear mistake eye and sharp water diuresis, facilitaing lung, eliminating the phlegm clearing heat-fire are moisturized；Cinnabar and jujube kernel have tranquilizing mind, The benefits of not normal insomnia of the mind, antitoxic heart-soothing and sedative, secondary nourishing the liver restlessness of asrhenia type and insomnia and palpitation with fear sign.
The Chinese medicinal formulae of the present invention have heat-clearing, diuresis relieving stagnant Qi disperse accumulation, resolving sputum dissipate ruffian, common invigorating spleen, benefiting qi for tranquillization, The effect of enriching the blood to restore normal menstruation, solution stasis of blood key spleen, checking exuberance of yang enriching yin, relieving stagnant Qi disperse accumulation, transquilization with heavy material and nourishing blood and tranquilization, there is antianxiety and treatment Depression acts on.
Specific embodiment
Embodiment：A kind of Chinese medicinal formulae for treating depression, it is characterised in that be made of the bulk pharmaceutical chemicals of following weight：The coptis 50g, cinnabar 0.15g, jujube kernel 30g, asparagus fern 20g, calamus 35g, amber 30g, earthworm 30g, radix bupleuri 30g, Rhizoma Chuanxiong 20g, Fu luxuriant growth 25g, Radix Polygalae 25g, thizoma curculiginis 10g, Radix Angelicae Sinensis 20g, Schisandra chinensis 30g.Campanulaceae 20g.
Medicament prepares and instructions of taking：By a kind of Chinese medicinal formulae for treating depression of the present invention, by the cinnabar list of its prescription Only weighing is simultaneously ground into as Fine ends individually packaging, then weighing is placed in mixing in decocting medicine pot respectively by other all medicines in its prescription, It adds in 3 times of warm water of Chinese medicine total amount to impregnate 10 minutes, then heating decocts 50 minutes, filters to obtain first time liquid；The dregs of a decoction are added 2 again Times decocting is endured 40 minutes, filters to obtain second of liquid；The dregs of a decoction are added to 2 times of water again again, then are decocted 30 minutes, filter to obtain third time medicine Liquid；It liquid merging will stir well three times, respectively in early, middle and late one after each meal, cinnabar does not divide three equal parts carefully, and point early, middle and late clothes are originally Warm water is taken before prescription liquid；This Chinese medicinal formulae one dose per day continuously takes 21 days as a treatment course.
Model case is illustrated, using above-described embodiment Chinese medicinal formulae；
1st, Zhang, female, 41 years old, housework, people from Bin County of Heilongjiang Province.Readme during patient assessment：Illness 5 years in person often occurs It is panic and feel restless, be difficult to cool it, often insomnia, etc. diseases, often feel to live bored, through the first training of Harbin Hospital is diagnosed as depression, successively take that its hospital opens it is several control depression Western medicine, have the Western medicine such as mirtazapine tablets, Deanxit, It is preferable to start to take effect, Time of Administration is often long, and effect is just less good and side effect is big.Take the prescription of the present invention 2 course for the treatment of symptoms of agent mitigate, and take 4 course for the treatment of, and symptom disappears, and cross year end recurrence.
2nd, Zhang, man, 65 years old, the retired, people from Bin County of Heilongjiang Province.Patient's readme when medical：Illness 10 years, often goes out The symptoms such as existing heart famine palpitaition, confused and worried, emotional lability, hospital is diagnosed as depression, and is demonstrate,proved along with anxiety.For many years by clothes It is maintained with a variety of Western medicine such as sertraline hydrochloride piece mirtazapine tablets, estazolam piece, diazepam injection and Clonazepam piece, the state of an illness is frequent Again and again, still end is complete more, has a hunch and lives in not having temperament and interest.The patient started to take the Chinese medicinal formulae of the present invention in June, 2015, A course for the treatment of is taken, symptom is substantially reduced, takes 5 course for the treatment of altogether, Quan Yu, so far end recurrence.
3rd, field so-and-so, man, 38 years old, agriculture field boundary worker, San Jiang counties of Heilongjiang Province.Readme during patient assessment：Suffer from depression 4 years, It is really depression through hospital expert outpatient service, normal fear, palpitaition, tension headache, diet difficulty peace, anxiety, insomnia is passed through after illness, Start in March, 2015 to cure after taking 4 courses for the treatment of of Chinese medicinal formulae of the invention, not recur so far.

Claims (2)

1. a kind of Chinese medicinal formulae for treating depression, it is characterised in that be made of the bulk pharmaceutical chemicals of following weight：Coptis 10-60g, Zhu Sand 0.1-0.3g, jujube kernel 10g-40g, asparagus fern 10g-30g, calamus 25g-40g, amber 20g-35g, earthworm 25g-35g, radix bupleuri 25g-35g, Rhizoma Chuanxiong 15g-28g, Poria cocos 18g-30g, Radix Polygalae 25g, thizoma curculiginis 5g-15g, Radix Angelicae Sinensis 15g-25g, Schisandra chinensis 20g-40g, Campanulaceae 15g-25g.
2. a kind of Chinese medicinal formulae for treating depression according to claim 1, it is characterised in that by the raw material of following weight Medicine forms：Coptis 50g, cinnabar 0.15g, jujube kernel 30g, asparagus fern 20g, calamus 35g, amber 30g, earthworm 30g, radix bupleuri 30g, Rhizoma Chuanxiong 20g, Fu luxuriant growth 25g, Radix Polygalae 25g, thizoma curculiginis 10g, Radix Angelicae Sinensis 20g, Schisandra chinensis 30g.Campanulaceae 20g.
CN201611271494.2A 2016-12-22 2016-12-22 A kind of Chinese medicinal formulae for treating depression Pending CN108236665A (en)

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CN101306150A (en) * 2008-07-11 2008-11-19 谷国锋 Medicine for smoothing and keeping the nerves and preparation method thereof
CN101347581A (en) * 2008-08-22 2009-01-21 杨军岭 Chinese medicine preparation for treating anypnia induced by nervous prostration
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CN101130005A (en) * 2007-09-13 2008-02-27 尹克华 Traditional Chinese medicine for treating depression and insomnia after liver and cerebral apoplexy
CN101204575A (en) * 2007-12-20 2008-06-25 董建国 Chinese traditional medicine composite for depressive neurosis, preparation method and application thereof
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