CN108187186A - A kind of monitoring infusion and vital sign detecting system - Google Patents

A kind of monitoring infusion and vital sign detecting system Download PDF

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Publication number
CN108187186A
CN108187186A CN201711442326.XA CN201711442326A CN108187186A CN 108187186 A CN108187186 A CN 108187186A CN 201711442326 A CN201711442326 A CN 201711442326A CN 108187186 A CN108187186 A CN 108187186A
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China
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module
drop
monitoring
control
infusion
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CN201711442326.XA
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CN108187186B (en
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严如强
周梦杰
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Southeast University
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Southeast University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804Flow controllers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/18General characteristics of the apparatus with alarm

Abstract

The invention discloses a kind of monitoring infusion and life sign monitor systems, including dual power supply module, control unit, detect drop/level sensing module of drop and liquid level, acquire the ecg information collection module of ecg information, acquire the pulse information acquisition module of pulse information, acquire the blood pressure information acquisition module of blood pressure information, store the memory module of gathered data, warning reminding module, monitoring showing interface and the LCD display for showing monitor value, setting/function selecting module that user independently selects corresponding monitoring function and arrange parameter and alarm threshold value function is provided, information and setting data transmission are blocked to drop speed/blocking control module of control to the wireless transport module of data management computer analyzing and processing fusion and for the control to transfusion drip speed and transfusion stop.The present invention can carry out infusion process and Human Physiology major parameter autonomous monitoring in real time, help to mitigate the working strength of medical staff;And it can realize the health monitoring of user itself.

Description

A kind of monitoring infusion and vital sign detecting system
Technical field
The present invention relates to medical instrument and health monitoring field, more particularly to a kind of monitoring infusion and vital sign monitoring system System.
Background technology
Venous transfusion is as treatment means very important in medical treatment and nursing, because rapid, curative effect is fast, stimulation is small etc. is administered The application of feature clinically is very universal, and it is effectively the working contents of ward nurse to ensure venous transfusion process safety, But this artificial monitoring not only increases the working strength of medical staff, and is easy to because misoperation causes shield and suffers from contradiction. During infusion, whole monitoring can not be also carried out to infusion, it is inadequate in a manner that manual pulley controls liquid flow velocity Accurately, manual adjustment cannot be met the requirements.So it is also modern intelligence that the detection of speed and accurate control are dripped in infusion process It is solved the problems, such as required for medical field.
The aggravation of aging degree and the continuous promotion of people's self health consciousness so that people are to health care quality Requirement be also continuously improved.Pulse, heart rate, electrocardio, blood pressure etc. are the basic expressions of human life activity, are referred to as life entity Sign, these activities are stablized relatively in a certain range, then imply that human body has been likely to occur pathology when it is varied widely Variation, to the monitoring of vital sign as a kind of health supervision technology, gradually by people, the particularly middle-aged and the old favor and Pay attention to, vital sign monitoring device suffers from consequence and preferable development prospect in all respects.
Monitoring infusion and life sign monitor system can consider intravenous transfusion monitoring and vital sign monitoring, complete To the progress such as liquid drop speed, residual volume of solution, liquid level monitoring in real time and alarm in infusion process, and pass through step motor control mould Block maintains drop speed to stablize, and has abandoned traditional method that drop speed is controlled by pulley;Human body can be given birth in infusion process simultaneously It orders sign (electrocardio, pulse, blood pressure etc.) and carries out real-time acquisition testing and analyzing and processing, have to current medical domain inestimable Meaning.On the one hand, the labor intensity for largely reducing medical staff is monitored and controlled in the automatic of infusion process, improves Safety and reliability in infusion process, sufferer and family members can also be rested well.On the other hand, traditional life Sign detecting instrument measurement function is single, can only be in the specific applications place such as hospital or health-center, and volume is larger not portable enough, no Suitable for places such as field, family and community medicines.The present invention designs a kind of monitoring infusion and life sign monitor system, with solution The problem of certainly mentioned above.
Invention content
Goal of the invention:For the above problem during the existing medical monitoring device of solution and venous transfusion, realization was infused The automatic monitoring of drop speed/liquid level in journey and multiple human body physiological parameters monitor simultaneously, the present invention provide a kind of monitoring infusion and Life sign monitor system.
Technical solution:A kind of monitoring infusion and life sign monitor system of the present invention, the system include dual power supply Module, control unit, drop/level sensing module, ecg information collection module, pulse information acquisition module, blood pressure information are adopted Collection module, memory module, warning reminding module, LCD display, setting/function selecting module, wireless transport module and drop speed/ Block control module;
The dual power supply module is used to provide electric energy to whole system;Drop/the level sensing module, electrocardio letter Cease acquisition module, pulse information acquisition module, blood pressure information acquisition module, memory module, warning reminding module, LCD display, Setting/function selecting module, wireless transport module and drop speed/blocking control module are electrically connected with control unit;
Drop/the level sensing module is used to detect drop and liquid level;The ecg information collection module is used to acquire Ecg information;The pulse information acquisition module is used to acquire pulse information;The blood pressure information acquisition module is used to acquire blood Press information;The data that the memory module acquires for storage;Setting/the function selecting module is capable of providing user and independently selects Corresponding monitoring function and arrange parameter and the function of alarm threshold value are selected, can pass through warning reminding mould when abnormal conditions occur Block notifies user or medical staff in time;LCD display module is used to guard showing interface and shows monitor value;Drop speed/the resistance Disconnected control module is used to block control to the control of transfusion drip speed and transfusion stop;Wireless transport module by various monitoring informations and It sets data transmission to data management computer and analyzes and processes fusion.
Wherein, in the drop/level sensing module, drop/liquid level sensor is installed on the Mo Fei in intravenous transfusion device On formula dropper, wherein liquid drop sensor is located at the top of Murphy's dropper, and liquid level sensor is located at the lower bottom part of Murphy's dropper, Drop speed and liquid level can be monitored simultaneously, and LCD display is sent to show;Drop speed/blocking the control module includes stepper motor, step Stepper motor driving circuit and slide push rod are installed on away from the woven hose of Mo Feishi droppers lower part, before stepper motor drives screw Into or retreat and squeeze woven hose, realize that control to transfusion drip speed and transfusion stop block control.
Further, the liquid drop sensor uses correlation infrared receiving/transmission pipe IR928-6C/PT928-6C, infusion process In, according to the drippage situation of drop, reception pipe output terminal exports square-wave signal after the processing of corresponding signal conditioning circuit, with The I/O port electrical connection of control unit, the liquid level sensor use DFRobot contactless liquid level sensors, water according to where it The exportable pulse signal of the presence or absence of liquid on horizontal line, output are electrically connected with the I/O port of control unit.
Wherein, the ecg information collection module, including leading electrode, conducting wire, EGC sensor and signal condition Three conducting wires of circuit, wherein EGC sensor are connected with leading electrode, are distinguished using pressurization right upper extremity unipolar lead mode It is placed on the right arm, left arm and left leg of measured;The pulse information acquisition module, including pulse transducer and signal condition Circuit, pulse transducer wherein pulse transducer are positioned at human body left or right hand wrist radial artery;The blood pressure information is adopted Collect module, including cuff, inflator pump and control circuit, wherein cuff is positioned over human body large arm, and cuff lower edge is away from fossa cubitalis band 2- At 3cm.
Further, the EGC sensor uses HKD-10A analog quantity EGC sensors, and Ag/AgCl electrodes, which are used as, to be drawn Conductive electrode is affixed on human body corresponding position;The pulse transducer uses HK-2000B type pulse transducers, passes through PVDF piezoelectric film Element sensed pressure changes;The blood pressure sensor module uses SUPERNIBP200A blood pressure measurement modules, and and control unit It is realized and communicated by UART1 serial ports.
Wherein, the memory module uses SD card memory mechanism, for store drip fast setting value, total liquid measure, Residual liquid, Drop speed, electrocardio, pulse and monitoring of blood pressure data in real time, pass through SPI serial communications between SD card and control unit;The alarm mould Block includes buzzer and NPN triode, is electrically connected with control unit;The LCD display is led to control unit by SCI News, realize the display of various monitoring informations and prompting message;The setting/function selection key module is single with control using button Member electrical connection realizes each monitoring threshold setting of setting and the function that function selects using inquiry mode detection button.
Wherein, the dual power supply module uses power supply adaptor, and output is connected with the input of power management chip, It is connected through peripheral resistance capacitance and field-effect tube with rechargeable lithium battery, power supply adaptor output and the output of lithium battery pass through two A diode realizes adapter power supply and the automatic switchover of lithium battery power supply.
Wherein, the monitoring system includes the real-time inspection and control thread of infusion process, includes the following steps:
(1) setting drop speed, liquid total amount and remaining liquid warning reminding amount send to drop speed/blocking control module and reset Signal opens droplet counting and interrupts interruption low with liquid level;
(2) WatchDog Timer interruption is opened, enabling signal is sent to liquid drop sensor and liquid level sensor;
(3) when timer timing arrives, calculating is practical to drip speed and residue liquid volume;
(4) the fast and remaining liquid volume of practical drop is respectively compared with setting value, and drop speed is adjusted in control motor, and data are protected It deposits and transmits, abnormal conditions alarm if the low down trigger of liquid level, controls motor to block infusion, otherwise transfusion stop is transferred to step Suddenly (2).
Wherein, the monitoring system includes ecg information collection processing thread and pulse information acquisition process thread, including Following steps:
(1) read functions setting command or the acquisition of reception data management computer, open TimerA timer interruptions;
(2) timer count overflows, then performs interrupt service routine, proceeds by ADC samplings;
(3) ADC samplings are completed, and are read data and are preserved, and LCD display is sent to show that simultaneously active transmission to data management calculates Otherwise machine continues waiting for ADC and completes sampling.
Wherein, the monitoring system includes blood pressure information acquisition process thread, includes the following steps:
(1) read functions setting command or the acquisition of reception data management computer, serial ports UART1 send blood pressure inspection Instruction is surveyed to blood pressure detecting module;
(2) blood pressure measurement module starts to detect pressure value, if receiving measurement terminates order, measures and terminates and be transferred to step (1);
(3) it reads blood pressure measurement and preserves data, LCD display is sent to show that simultaneously active transmission to data management calculates Machine.
Advantageous effect:Compared with prior art, the present invention is not only able to carry out automatically to dripping speed and liquid level in infusion process Monitoring, sufferer and family members can also be rested well while alleviating medical staff's working strength, additionally it is possible in infusion The monitoring of human body vital sign (physiological parameter) is realized simultaneously, can also be used separately as vital sign monitor, is introduced wireless On the one hand transmission and computer management data mode provide valuable physiological parameter historical data for the health control of itself, Diagnosis for doctor provides data foundation, while dual power supply module is used to simultaneously cope with suddenly to whole system offer electric energy The emergency cases such as power failure, meet the needs of being used in a variety of places such as community medicine, family and open air, alleviate to a certain extent Imbalance between supply and demand has potential economic society value.In addition, the present invention can be to infusion process and Human Physiology major parameter Autonomous monitoring in real time is carried out, on the one hand contributes to mitigate the working strength of medical staff;On the other hand user itself can be realized Health monitoring, valuable physiological parameter historical data for the health control of itself is provided, there is certain economic value.
Description of the drawings
Fig. 1 is the monitoring infusion of the present invention and the circuit frame of life sign monitor system;
Fig. 2 is drop/liquid level sensor of the present invention and drop speed/blocking control mounting arrangement figure;
Fig. 3 is electrocardio, pulse transducer and the blood pressure detecting module placement figure of the present invention;
Fig. 4 is the signal conditioning circuit connection figure of the present invention;
Fig. 5 is the dual power supply module connection figure of the present invention;
Fig. 6 is the MSP430F149 main program flow charts of the present invention.
Specific embodiment
Technical scheme of the present invention is described in detail below in conjunction with the accompanying drawings.
The invention discloses a kind of monitoring infusion and life sign monitor system, including dual power supply module, MSP430 Chip main control module, monitoring infusion module, vital sign monitoring modular, setting/function selecting module, LCD display module and nothing Line transmission module.Wherein, the monitoring system can realize that four roads work according to setting demand:A drips speed/liquid in infusion process The real-time monitoring and control of position;B, human ECG monitoring;C, human pulse information monitoring;D, human blood-pressure information monitoring. In addition, dual power supply module is used to simultaneously cope with the emergency cases such as power failure suddenly to whole system offer electric energy, meet in society The demand used in a variety of places such as area's medical treatment, family and open air;Setting/function selecting module is capable of providing user and independently selects Corresponding monitoring function and arrange parameter and the function of alarm threshold value, can pass through warning reminding module when abnormal conditions occur User or medical staff are notified in time, to take counter-measure in time;LCD display module is used to guard showing interface and show Monitor value;Wireless transport module passes the information such as infusion information, vital sign (electrocardio, pulse and blood pressure) information and setting data Data management computer analyzing and processing fusion is transported to, so that medical staff assesses the health status of user.
The system can realize real time monitoring and human body vital sign (or being human body physiological parameter) in infusion process Monitoring, corresponding function can independently be selected by setting/function selecting module, and the information monitored can be with real-time display in LCD , can be by warning reminding module automatic alarm when abnormal conditions occur on display screen, while all information monitored pass through Wireless way for transmitting is to data management computer, so as to medical staff's observational record and analysis, based on MSP430F149 Chip (i.e. control unit) is controlled, coordinates the orderly work of each module.
Content includes:
The circuit frame of A, monitoring infusion and life sign monitor system, by dual power supply module, MSP430F149 Processing chip, drop/liquid level sensor, drop speed/blocking control stepper motor, EGC sensor, pulse transducer, blood pressure sensing Device module, memory module, alarm module, LCD display, setting/function selection key module and wireless transport module composition;
The software main thread of B, the monitoring infusion and life sign monitor system, including:The real-time monitoring of infusion process Control thread, blood pressure information acquisition process thread, ecg information collection processing thread and pulse information acquisition process thread.
The system include dual power supply module, control unit, drop/level sensing module, ecg information collection module, Pulse information acquisition module, blood pressure information acquisition module, memory module, warning reminding module, LCD display, setting/function choosing Select module, wireless transport module and drop speed/blocking control module.Wherein, dual power supply module is used to provide to whole system Electric energy;Drop/level sensing module, pulse information acquisition module, blood pressure information acquisition module, is deposited at ecg information collection module Store up module, warning reminding module, LCD display, setting/function selecting module, wireless transport module and drop speed/blocking control mould Block is electrically connected with control unit.
Wherein, drop/level sensing module is used to detect drop and liquid level;Ecg information collection module is used to acquire electrocardio Information;Pulse information acquisition module is used to acquire pulse information;Blood pressure information acquisition module is used to acquire blood pressure information;Store mould The data that block acquires for storage;Setting/function selecting module is capable of providing user and independently selects corresponding monitoring function and set The function of alarm threshold value is put, can user or medical staff be notified by warning reminding module in time when abnormal conditions occur; LCD display module is used to guard showing interface and shows monitor value;Speed/blocking control module is dripped for the control to transfusion drip speed It blocks and controls with transfusion stop;Wireless transport module melts information and setting data transmission to data management computer analyzing and processing It closes.
As shown in Figure 1, the circuit frame of the monitoring infusion and life sign monitor system, by dual power supply mould Block, MSP430F149 main control chips, drop/level sensing module, drop speed/blocking control module, ecg information collection module, arteries and veins It fights information acquisition module, blood pressure information acquisition module, SD card memory module, warning reminding module, LCD display, setting/function Selecting module and wireless transport module composition.It can be seen from figure 1 that be electrically connected with control unit (MSP430F149 main control chips) There are drop/level sensing module, ecg information collection module, pulse information acquisition module, setting/function selecting module, blood pressure Information acquisition module, LCD display, wireless transport module, SD card memory module and warning reminding module and stepper motor (drop Speed/blocking control module).
Drop speed/blocking the control module drives push rod to move forward or back movement and squeezes woven hose using stepper motor, real The purpose that now control of drop speed and transfusion stop block;The memory module uses SD card memory module, SD card and MSP430F149 Processing chip is realized data storage by SPI serial communications and is read, the P5 ports of the unit in order to control of port used in SPI;It is described Wireless transport module is connected using GPRS module with control unit, and control unit sum number is realized by UART0 serial ports According to the transmitted in both directions of data between management computer, UART0 communications occupy P3.4 the and P3.5 pins of control unit.
Setting/the function selecting module realizes parameter setting and detection function choosing by the way of program scanning button It selects, multiple button composition matrix keyboard forms are connect with control unit, occupy the P2 ports of control unit;The LCD is shown Panel module is connect using SCI communication modes with control unit, is realized that data are shown, is occupied the P3 ports of control unit;It is described Warning reminding module is made of triode Q8050 and buzzer, and the base stage of triode is connected with the P4.7 pins of control unit, control Unit processed controls buzzer sounding by exporting low and high level, realizes the purpose of warning reminding.
As shown in Fig. 2, drop/liquid level sensor of drop/level sensing module and drop speed/blocking control module installation cloth Office, for security reasons, liquid medicine contamination, detection sensor (drop/liquid level sensor) and drop speed control are single in order to prevent Member (drop speed/blocking control module) cannot be contacted directly with liquid, it can be seen in fig. 2 that drop and liquid level sensor pass through admittedly Determine on the Mo Feishi droppers that device is installed in intravenous transfusion device, wherein liquid drop sensor is located at the top 1/3 of Murphy's dropper Place must assure that drop is in before drippage on the infrared beam that the transmitting terminal of liquid drop sensor and receiving terminal are formed, Prevent drop interference sensor response before convergence is dripped.Liquid level sensor is located at the lower bottom part of Murphy's dropper, such as institute in Fig. 2 Show, when specific implementation need to ensure that pipe Chinese medicine liquid is higher than the probe top of liquid level sensor in vertical direction.Drip speed/blocking control Module (including stepper motor) is installed on by fixing device away from Mo Feishi droppers lower part 5cm, and woven hose is stuck in baffle and pushes away Between bar, stepper motor drives push rod to move forward or back and squeezes woven hose, realizes the control to transfusion drip speed and transfusion stop resistance Disconnected control.
Wherein, liquid drop sensor is high intensity using correlation infrared receiving/transmission pipe IR928-6C/PT928-6C, IR928-6C Light emitting diode, can penetrate plastic infusion dropper emit infrared ray, have high radiance, peak wavelength 940nm, by Driving circuit driving shines, and light path is formed between reception pipe, and detection droplet theory is:In infusion process, when under drop It falls when sheltering from light beam, due to energy attenuation, the optical signal that reception pipe receives is weaker, and reception pipe is insufficient to allow to be connected;Work as liquid When drop does not block light beam, reception pipe receives the optical signal of sufficient intensity, reception pipe conducting.According to the drippage situation of drop, receive Pipe output terminal exports square-wave signal after corresponding shaping circuit (signal conditioning circuit) processing, the I/O port electricity with control unit Connection, control unit are realized by capturing rising edge or the failing edge of square-wave signal to droplet counting.The level sensing Device uses DFRobot contactless liquid level sensors, equally drives (power supply) by driving circuit, operation principle is:When having When liquid is in the residing horizontal and vertical region of its probe, high level is exported, otherwise exports low level.It is completed when infusing, Murphy's dropper inner liquid medicine is constantly reduced, when liquid level is less than below probe detection region, liquid level sensor output level saltus step letter Number, input control unit after shaped circuit shaping.
Wherein, shaping circuit is made of voltage comparator LM393 and filter capacitor, and liquid drop sensor receiving terminal passes through shaping Circuit output square-wave signal, liquid level sensor export skip signal by shaping circuit.Speed/blocking control module is dripped by stepping electricity The compositions such as machine, stepper motor driving circuit and slide push rod.Stepper motor driving circuit is mainly by ULN2003 driving chip groups Into, be internally integrated high voltage, the NPN Darlington transistors of high current, only need 5V power voltage supplies just can Driving Stepping Motor, stepping To reach, automatic adjustment drop speed and realization infusion are abnormal, terminate by the way that slide push rod is driven to move forward or back extruding woven hose for motor The purpose of infusion is blocked, the output pin of ULN2003 driving chips is connected by two-phase four-wire system mode with stepper motor, is inputted Pin is connected with control unit, occupies the P4 ports of control unit.Stepper motor model is 24BYJ-48, and parameter is:Step pitch Angle is 5.625 °/64, reduction ratio 1:64,4 phases, 5V power supplies.Control unit can be controlled by controlling the umber of pulse of output The rotational angle of motor, rotational angle formula are as follows:
ω=θN×N (1);
Wherein, θNFor stepping motor single pulse step angle, N is step-by-step impulse number, is dripped in fast controlling cycle, practical drop speed with Setting drop speed, which makes the difference, is worth to △ T, using segmented PID control stepper motor degree of rotation, and then slide push rod is controlled to advance Or the distance (degree for squeezing woven hose) retreated realizes the auto-adjustment control of drop speed.Propulsion or backway calculation formula It is as follows:
S=Ki×△T×θN(2);
Wherein, the distance (amplitude) that S is moved forward or back for slide push rod, KiFor proportionality coefficient, carried out according to the size of △ T Segmentation, △ T are bigger, corresponding KiAlso it is bigger, it is on the contrary then smaller, i.e., when practical drop speed differs greatly with setting drop speed, stepping electricity Machine can be rapidly performed by the adjusting of drop speed;When difference is smaller, stepper motor slowly finely tunes drop speed to setting value, reaches point Segmentation PID adjusts the purpose of drop speed.
As shown in figure 3, electrocardio, pulse transducer and blood pressure detecting module placement, ecg information collection module includes electrocardio Sensor, three conducting wires of leading electrode, conducting wire and signal conditioning circuit, wherein EGC sensor respectively with leading electrode It is connected, using Ag/AgCl electrodes as leading electrode, the skin surface to user with 75% medicinal alcohol is needed before use It carries out disinfection, to reduce the contact noise between electrode and skin, improves the pickup capacity of leading electrode, obtain the electrocardio of high quality Leading electrode is individually positioned in tested by signal waveform by the way of pressurization right upper extremity unipolar lead (aVR) as shown in Figure 3 3cm places (RA) above wrist joint on the inside of the right arm of person, (LA) and left leg lower limb shin bone internal malleolus at the 3cm of wrist joint top on the inside of left arm At the 7cm of top (LL), EGC sensor output is connected with the input of signal conditioning circuit, and it is single that control is input to after signal condition First (MSP430F149 main control chips) carries out ADC acquisitions.Pulse information acquisition module includes pulse transducer and signal condition electricity Road, wherein pulse transducer are positioned at human body left or right hand wrist radial artery, and output is equally improved through signal conditioning circuit After be input to control unit carry out ADC samplings., blood pressure information acquisition module includes cuff, inflator pump and control circuit, and cuff puts Be placed in human body large arm, cuff lower edge away from fossa cubitalis band 2-3cm at, output is connected with control unit UART1 serial ports, control unit Blood pressure information acquisition module only need to be sent instructions to, so that it may realize the automatic collection of blood pressure information, acquire and returned blood pressure information It is transmitted to control unit.
Primary spectrum ranging from 0.05~100Hz of electrocardiosignal (ECG), and 90% ECG spectrum energies are mainly concentrated Between 0.25~35Hz, amplitude range is about 0~4mV, therefore electrocardiosignal belongs to low-frequency weak signal.Specific embodiment In, EGC sensor uses HKD-10A analog quantity EGC sensors, and technical parameter is:Signal amplification factor is 475 times;Altogether It is 65dB that mould, which inhibits than CMRR,;Input impedance is up to 106MΩ;It is internally integrated high-pass filter and extracts electrocardio with low-pass filter The Domain energy channel of signal (ECG), i.e. 0.05~100Hz;Internal 50Hz notch filters circuit, can effectively filter out 50Hz works Frequency signal.Pulse transducer uses HK-2000B type pulse transducers, is pressed caused by perceiving pulsation by PVDF piezoelectric film element Power changes, and realizes the measurement of pulse signal.
Wherein, blood pressure sensor module uses SUPERNIBP200A blood pressure measurement modules, with MSP430F149 master control cores Piece is realized by UART1 serial ports and communicated, and is communicated as Transistor-Transistor Logic level mode, baud rate 4800bps, and each pin of module is defined as follows Shown in table:
Between blood pressure information acquisition module and control unit serial port communicating protocol has been formulated, it is specified that the form of communication, referring to Order and return data packet, specially:The stop position of data bit+1 of start bit+8, no parity check position.Control unit, which is sent, measures life Measurement method, measurement period time, measurement pattern, the setting of pre-charging pressure value and blowby gas path detection etc. are included in order.Such as Measuring command " 02 30 31 3B 3B 44 37 03 ", then it represents that open blood pressure automatic measurement;Order " 02 30 37 3B 3B 44 39 03 " expression is arranged to automatic measurement pattern that the period is 60 minutes etc.;If module receives order at any time " X ", then it represents that terminate and measure.Specifically blood pressure measurement is:A) control unit sends measuring command;B) blood pressure information acquisition mould Block receives order, and cuff inflation simultaneously detects pressure in cuff automatically;C) when pressure reaches setting value, cuff deflation simultaneously continues to detect Pressure in cuff, until pressure is 0;D) measurement result is sent to control unit by blood pressure information acquisition module.
As shown in Figure 3 and Figure 4, as can be seen from Fig. 3, the output of pulse and EGC sensor is all needed through at signal conditioning circuit It could controlled unit progress ADC samplings after reason.Referring to Fig. 4, the specific conditioning step of signal is:A) sensor output value by The voltage inversion ratio circuit of LM358 compositions carries out reverse phase processing, exports forward voltage values;B) the level lifting of LM358 compositions Circuit is step A) in voltage carry out lifting processing, make level be lifted after signal meet control unit (MSP430F149 master Control chip) the met voltage range of ADC acquisitions;C) control unit carries out ADC acquisitions.
In specific implementation process, ECG detecting uses augmented unipolar right upper extremity lead mode, and HKD-10 EGC sensors obtain The ecg wave form amplitude voltage range taken about -0.8~0V, presentation reverse phase, i.e. ECG signal presentation inverted image, and control unit Supply voltage is 3.3V, and the voltage range for carrying out ADC acquisitions is 0~3.3V, therefore analog quantity electrocardiosignal is carrying out A/D turns Before alternatively, the output signal of sensor need to be carried out to reverse phase and level lifting conditioning.In Fig. 4, signal is through first order reverse phase ratio Circuit conditioning after, output amplitude ranging from 0.0~1.6V, then through second level level be lifted circuit, output amplitude ranging from 0.8~ 2.4V reaches the voltage range requirement that control unit carries out ADC acquisitions.Similar with EGC sensor, pulse transducer is original defeated It is about -0.2~1V to go out voltage magnitude, while needs signal conditioning circuit that could carry out A/D conversions, specific implementation process after handling In, output area is after conditioned circuit conditioning:0.4~2.8V, the voltage range for reaching control unit progress ADC acquisitions will It asks.
As shown in Figure 1 and Figure 5, a kind of monitoring infusion and life sign monitor system, use dual power supply Module provides electric energy for whole system.As can be seen from Fig. 5, dual power supply module is filled by power supply adaptor, MAX1873 lithium batteries Electric control module, rechargeable lithium battery and output handover module composition.Wherein, power adapter plug is inserted into 220V exchanges city Electricity exports stable direct current 8.4V, electric current 800mA, on the one hand output is connected with the input of power management chip MAX1873, Output is passed through and is connected through peripheral resistance capacitance and field-effect tube NDS8435A with rechargeable lithium battery, meanwhile, control unit is regular ADC acquisitions are carried out to lithium battery voltage, monitor electricity, MAX1873 is realized by two control loops of electric current and voltage to lithium electricity Cell voltage and charging current take over seamlessly control, and pass through another control loop and realize current regulation to input source; Power supply adaptor on the other hand output access output handover module, while rechargeable lithium battery output also access outputting cutting mold changing Block, output handover module are made of two diodes.Dual power supply switching principle is:When there is alternating current, power supply adaptor is defeated Go out voltage higher than rechargeable lithium battery voltage, output handover module only allows power supply adaptor output to power for whole system;When Have a power failure or in the case that other do not have alternating current, rechargeable lithium battery voltage higher than power supply adaptor output voltage, (fit at this time by power supply Orchestration is without output), output handover module only allows rechargeable lithium battery to provide electric energy for whole system.
As shown in fig. 6, for monitoring infusion and the software main thread of life sign monitor system, mainly including following Aspect:The automatic monitoring of infusion process, blood pressure information acquisition process, electrocardio and pulse information acquisition process etc., can from Fig. 6 See, main process flow steps are as follows:
(1) it initializes:Including system clock initialization, each port initialization of control unit, serial communication initialization, ADC Digital analog converter initializes and timer initializes etc., and opens total interrupt;
Wherein in initialization procedure, main control unit port used is described as follows:
(2) the necessary presentation of information of LCD display, such as bed number, instrument number etc., inquiry button setting command and waiting Receive order;
(3) address matching if not the machine address, then returns and continues to inquire, if the machine address, illustrate address matching into Work(, according to being set into three main separated time journeys after address matching success.
Wherein, the real-time inspection and control thread of infusion process, implementation steps are:
(1) parameter setting
Setting drop speed, liquid total amount, remaining liquid warning reminding amount (acquiescence drop fast 50 drops/minute, per bottle liquid medicine total amount 500ml, remaining liquid warning reminding amount 20ml), stepper motor drop speed/blocking control module resets, and opens in P1 mouthfuls of droplet countings Disconnected, the low interruption of liquid level.
(2) WDT timer interruptions are opened
WatchDog Timer interruption is opened, liquid drop sensor, liquid level sensor are started to work.
(3) judge timing
It is arrived when the timer timing 6s times, calculates practical drop speed:V=10 × △ T, wherein △ T are number of drops in the 6s times, Calculate remaining liquid volume:Vres=Vsum- 0.05*C, wherein VsumIt is infusion coefficient for the liquid total amount set in step A, 0.05 (infusion apparatus decision) is the drop total amount monitored that is, per drop of liquid volume 0.05ml, C;If timing does not arrive, return It is inquired.
(4) practical drop speed, remaining liquid volume etc. are respectively compared with setting value, and drop speed is adjusted in control motor, data It preserves and transmits, abnormal conditions alarm if the low down trigger of liquid level, controls motor to block infusion, transfusion stop.
Wherein, electrocardio/pulse information detection process thread, implementation steps are:
(1) TimerA timer interruptions are opened
Read functions setting command or the acquisition for receiving data management computer, open TimerA timer interruptions;
(2) judge to count and whether overflow
If timer count overflows, interrupt service routine is performed, ADC samplings are proceeded by interrupt service routine; Otherwise, inquiry timer count is carried out;
(3) ADC samplings are completed, and are read data and are preserved, and LCD display is sent to show that simultaneously active transmission to data management calculates Otherwise machine continues waiting for ADC and completes sampling.
In specific implementation process, ADC digital analog converters initialize when, setting 2.5V be internal reference voltage, sequence single Sampling configuration, since the frequency of electrocardiosignal and pulse signal is concentrated mainly in the range of 0.05-100Hz, according to interior Qwest Sampling thheorem, when timer A is initialized, the sample frequency for setting ADC is 200Hz.In electrocardio/pulse detection thread, timer Implementation procedure in interrupt service routine is:It is interrupted into timer A;Start ADC conversions;Waiting converts, if completing Change data is read, if electrocardiogram (ECG) data is then and in preservation to one-dimension array ECG [128];Electrocardio of the flag bit to acquisition is set Data are counted, and when counting reaches 128, open up the FFT transform that FFT transform thread carries out data in array 128 points, Obtain the frequency spectrum of electrocardiosignal (ECG) signal;Heart rate value is calculated according to frequency spectrum, in this way pulse data, then pass through threshold value comparison, note Unit interval class beat pulse number is recorded, calculates pulse frequency;Data preserve and are transmitted to data management computer.
Wherein, blood pressure information acquisition process thread, implementation steps are:
(1) read functions setting command or the acquisition of reception data management computer, serial ports UART1 send blood pressure inspection Instruction is surveyed to blood pressure detecting module;
(2) blood pressure information acquisition module starts to detect pressure value, if receiving measurement terminates order, measures and terminates and be transferred to step Rapid A;
(3) it reads blood pressure measurement and preserves data, LCD display is sent to show that simultaneously active transmission to data management calculates Machine.
Wireless transport module realizes the communication between control unit and data management computer, and transmission module uses GPRS moulds Block is connected with the UART0 of control unit.UART0 initialization of (a) serial ports, formulation data format be 8 data bit, 1 stop position, nothing Check bit, baud rate 9600bps.Data management computer is to communication instruction that monitoring system issues (under send instructions) form system It is fixed as follows:
Wherein, lead code is the mark of data frame, is herein fixed value 0xDA;Address code includes source address and destination Location, two byte lengths, source address are data management computer address, and destination address is each address for monitoring system;Order It is monitoring infusion that the monitoring system Monitoring instruction to be performed, 1 byte long, such as 30H are included in code, and 31H is acquisition electrocardio, 32H is acquisition pulse, and 33H is acquisition blood pressure etc.;Reservation paragraph is used for command sets extension;Check code is the check code per frame data.Prison It is as follows that examining system is transmitted to the formulation of data management computer data frame format:
Monitoring system during the work time, periodically uploads data, wherein, lead code, address code, command code and check code Identical with issuing instruction definition, difference is that lead code is set as 0xDD herein;Wherein data paragraph format is:
Byte 1-6 7-16 17-29 20-22 23-25 26-27
Description Time Infusion information Ecg information Pulse information Blood pressure information Electricity
Wherein infusion information includes bed label, drop speed, total amount of infusing, prompting amount, practical drop speed, surplus etc..In addition do not have The function of unlatching, then corresponding monitor value be all set to 0, when such as only carrying out ECG detecting, infusion, pulse and blood pressure information are all 0. SD is also stored when storing according to the form.

Claims (10)

1. a kind of monitoring infusion and life sign monitor system, it is characterised in that:The system includes dual power supply module, control Unit, ecg information collection module, pulse information acquisition module, blood pressure information acquisition module, is deposited drop/level sensing module Store up module, warning reminding module, LCD display, setting/function selecting module, wireless transport module and drop speed/blocking control mould Block;
The dual power supply module is used to provide electric energy to whole system;Drop/the level sensing module, ecg information are adopted Collection module, blood pressure information acquisition module, memory module, warning reminding module, LCD display, is set pulse information acquisition module Put/function selecting module, wireless transport module and drop speed/blocking control module be electrically connected with control unit;
Drop/the level sensing module is used to detect drop and liquid level;The ecg information collection module is used to acquire electrocardio Information;The pulse information acquisition module is used to acquire pulse information;The blood pressure information acquisition module is believed for acquiring blood pressure Breath;The data that the memory module acquires for storage;Setting/the function selecting module is capable of providing user and independently selects phase The monitoring function and arrange parameter and the function of alarm threshold value answered, when abnormal conditions occur can by warning reminding module and Shi Tongzhi user or medical staff;LCD display module is used to guard showing interface and shows monitor value;Drop speed/blocking the control Molding block is used to block control to the control of transfusion drip speed and transfusion stop;Wireless transport module is by various monitoring informations and setting Data transmission is analyzed and processed to data management computer and is merged.
2. a kind of monitoring infusion according to claim 1 and life sign monitor system, it is characterised in that:The drop/ In level sensing module, drop/liquid level sensor is installed on the Mo Feishi droppers in intravenous transfusion device, wherein liquid drop sensor Positioned at the top of Murphy's dropper, liquid level sensor is located at the lower bottom part of Murphy's dropper, can monitor drop speed and liquid level simultaneously, And LCD display is sent to show;Drop speed/blocking the control module is pushed away including stepper motor, stepper motor driving circuit and slip Bar is installed on away from the woven hose of Mo Feishi droppers lower part, and stepper motor drives screw to move forward or back and squeezes woven hose, realizes Control and transfusion stop to transfusion drip speed block control.
3. a kind of monitoring infusion according to claim 2 and life sign monitor system, it is characterised in that:The drop passes Sensor uses correlation infrared receiving/transmission pipe IR928-6C/PT928-6C, in infusion process, according to the drippage situation of drop, receives Pipe output terminal exports square-wave signal after the processing of corresponding signal conditioning circuit, is electrically connected with the I/O port of control unit, described Liquid level sensor uses DFRobot contactless liquid level sensors, exportable arteries and veins of the presence or absence of liquid on horizontal line according to where it Signal is rushed, output is electrically connected with the I/O port of control unit.
4. a kind of monitoring infusion according to claim 1 and life sign monitor system, which is characterized in that the electrocardio letter Acquisition module is ceased, includes the three of leading electrode, conducting wire, EGC sensor and signal conditioning circuit, wherein EGC sensor Root conducting wire is connected with leading electrode, and the right arm of measured, left arm are individually positioned in using pressurization right upper extremity unipolar lead mode On left leg;The pulse information acquisition module, including pulse transducer and signal conditioning circuit, pulse transducer wherein pulse Sensor is positioned at human body left or right hand wrist radial artery;The blood pressure information acquisition module, including cuff, inflator pump and Control circuit, wherein cuff are positioned over human body large arm, cuff lower edge away from fossa cubitalis band 2-3cm at.
5. a kind of monitoring infusion according to claim 4 and life sign monitor system, it is characterised in that:The electrocardio passes Sensor uses HKD-10A analog quantity EGC sensors, and Ag/AgCl electrodes are affixed on human body corresponding position as leading electrode;It is described Pulse transducer uses HK-2000B type pulse transducers, is changed by PVDF piezoelectric film element sensed pressure;The blood pressure passes Sensor module uses SUPERNIBP200A blood pressure measurement modules, and is realized and communicated by UART1 serial ports with control unit.
6. a kind of monitoring infusion according to claim 1 and life sign monitor system, it is characterised in that:The storage mould Block uses SD card memory mechanism, drips fast setting value, total liquid measure, in real time Residual liquid, drop speed, electrocardio, pulse and blood for storing Monitoring data are pressed, pass through SPI serial communications between SD card and control unit;The alarm module includes tri- pole of buzzer and NPN Pipe, is electrically connected with control unit;The LCD display is communicated with control unit by SCI, is realized various monitoring informations and is carried The display for information of waking up;The setting/function selection key module is electrically connected with control unit using button, is examined using inquiry mode It surveys button and realizes the function that each monitoring threshold setting and function selection are set.
7. a kind of monitoring infusion according to claim 1 and life sign monitor system, which is characterized in that the dual power supply Power supply module uses power supply adaptor, and output is connected with the input of power management chip, through peripheral resistance capacitance and field-effect Pipe is connected with rechargeable lithium battery, and power supply adaptor output and the output of lithium battery realize that adapter is powered by two diodes With the automatic switchover of lithium battery power supply.
8. a kind of monitoring infusion according to claim 1 and life sign monitor system, which is characterized in that the monitoring system System includes the real-time inspection and control thread of infusion process, includes the following steps:
(1) setting drop speed, liquid total amount and remaining liquid warning reminding amount send reset signal to drop speed/blocking control module, It opens droplet counting and interrupts interruption low with liquid level;
(2) WatchDog Timer interruption is opened, enabling signal is sent to liquid drop sensor and liquid level sensor;
(3) when timer timing arrives, calculating is practical to drip speed and residue liquid volume;
(4) the fast and remaining liquid volume of practical drop is respectively compared with setting value, and drop speed is adjusted in control motor, and data preserve simultaneously Transmission, abnormal conditions alarm if the low down trigger of liquid level, control motor to block infusion, otherwise transfusion stop is transferred to step (2)。
9. a kind of monitoring infusion according to claim 1 and life sign monitor system, which is characterized in that the monitoring system System includes ecg information collection processing thread and pulse information acquisition process thread, includes the following steps:
(1) read functions setting command or the acquisition of reception data management computer, open TimerA timer interruptions;
(2) timer count overflows, then performs interrupt service routine, proceeds by ADC samplings;
(3) ADC samplings are completed, and are read data and are simultaneously preserved, and LCD display is sent show that simultaneously active transmission is to data management computer, Otherwise it continues waiting for ADC and completes sampling.
10. a kind of monitoring infusion according to claim 1 and life sign monitor system, which is characterized in that the monitoring System includes blood pressure information acquisition process thread, includes the following steps:
(1) read functions setting command or the acquisition of reception data management computer, serial ports UART1 send blood pressure detecting and refer to Enable blood pressure detecting module;
(2) blood pressure measurement module starts to detect pressure value, if receiving measurement terminates order, measures and terminates and be transferred to step (1);
(3) it reads and blood pressure measurement and preserves data, LCD display is sent show that simultaneously active transmission is to data management computer.
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CN110032092A (en) * 2018-12-03 2019-07-19 江苏省肿瘤医院 Transfusion drip speed monitors accurate management system and method
CN110624157A (en) * 2019-11-05 2019-12-31 郑佩勇 Medical venous transfusion monitoring system

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