CN108186937A - A kind of aloetic anti-acne drug and preparation method thereof - Google Patents
A kind of aloetic anti-acne drug and preparation method thereof Download PDFInfo
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- CN108186937A CN108186937A CN201810193532.XA CN201810193532A CN108186937A CN 108186937 A CN108186937 A CN 108186937A CN 201810193532 A CN201810193532 A CN 201810193532A CN 108186937 A CN108186937 A CN 108186937A
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- 238000011105 stabilization Methods 0.000 description 1
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- 230000003637 steroidlike Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
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- 231100000331 toxic Toxicity 0.000 description 1
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- 230000001988 toxicity Effects 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
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- 238000009777 vacuum freeze-drying Methods 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to medical anti-acne fields more particularly to a kind of aloetic anti-acne drug and preparation method thereof, which is grouped as by each group of following parts by weight：8 19 parts of aloe full leaf freeze-dried powder, 18 37 parts of aloe full leaf ovendry power, 28 parts of Radix Glycyrrhizae, 8 17 parts of cassia seed, 8 16 parts of Semen Coicis, 26 parts of Radix Angelicae Sinensis.Preparation method includes step picking of raw material, mixing compounding, filling, bubble-cap pressing plate and packaging, and the invention discloses a kind of aloetic anti-acne drug and preparation method thereof, which being capable of effectively anti-acne, ecchymose removing, antibacterial anti-inflammatory.Especially there is remarkable efficacy to complexion is withered and yellow caused by acne, acne, papule epifolliculitis, seborrheic dermatitis, pachylosis, color spot, freckle, abdominal distension, apocleisis, insomnia, endocrine disorder.Vivotoxin can be effectively excluded simultaneously, repair scar, strengthen immunity.
Description
Technical field
The present invention relates to medical anti-acne fields more particularly to a kind of aloetic anti-acne drug and preparation method thereof.
Background technology
With the fast development of society, people’s lives tempo increase, operating pressure is larger, and long-term evening such as sleeps at the bad habits
Endocrine disturbance can be caused, skin is caused various problems occur, such as acne, acne, papule epifolliculitis, seborrheic dermatitis, skin
Complexion caused by coarse, color spot, freckle, endocrine disorder is withered and yellow etc., these problems not only influence the health of people, also tight
Ghost image rings personal image.Existing product for resolving poxes includes cosmetics and drug, most of cosmetics price with anti-acne effect
Costliness, anti-acne effect unobvious, and existing anti-acne pharmaceutical chemistry ingredient toxicity is larger, side effect is more apparent, and drug withdrawal can recur
Rate is higher, and safety does not ensure.
Invention content
It is an object of the invention to overcome the deficiencies in the prior art, and provide a kind of aloetic anti-acne drug and its preparation
Method, which uses aloe powder, and for key component, Small side effects, anti-acne effect is good, can improve endocrine disturbance, can be effective
It excludes vivotoxin, repair scar, strengthen immunity.
The solution have the advantages that be achieved：A kind of aloetic anti-acne drug, by each of following parts by weight
Component forms：8-19 parts of aloe full leaf freeze-dried powder, 18-37 parts of aloe full leaf ovendry power, 2-8 parts of Radix Glycyrrhizae, 8-17 parts of cassia seed, the heart of a lotus seed
Rice 8-16 parts, 2-6 parts of Radix Angelicae Sinensis.
Preferably, which is grouped as by each group of following parts by weight：10-15 parts of aloe full leaf freeze-dried powder, aloe is complete
20-35 parts of leaf ovendry power, 3-5 parts of Radix Glycyrrhizae, 10-15 parts of cassia seed, 10-15 parts of Semen Coicis, 3-5 parts of Radix Angelicae Sinensis.
Preferably, which is grouped as by each group of following parts by weight：12 parts of aloe full leaf freeze-dried powder, aloe full leaf dry
28 parts of dry powder, 4 parts of Radix Glycyrrhizae, 13 parts of cassia seed, 12 parts of Semen Coicis, 5 parts of Radix Angelicae Sinensis.
Preferably, a kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following parts by weight：8-19 parts of aloe full leaf freeze-dried powder,
18-37 parts of aloe full leaf ovendry power, 2-8 parts of Radix Glycyrrhizae, 8-17 parts of cassia seed, 8-16 parts of Semen Coicis, 2-6 parts of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule mounted box that will be made, vanning, outbound after inspection.
Pharmacological property is analyzed：
Aloe full leaf freeze-dried powder selects Aloe Barbadensis Miller fresh leaf to extract through advanced technologies, stabilization processes, nothing after room temperature film degerming
Bacterium is filling, then is made through vacuum freeze drying, contains barbaloin, aloe polysaccharide, anthraquinone compounds, rutin, protein, organic
The plurality of active ingredients such as acid, amino acid and trace element are pale yellow powder, and gas stink is bitter, improve a poor appetite, large intestine delay let out,
Soothing the liver invigorating the spleen and the effect of heat-clearing and fire-reducing, can strengthen stomach function, improve the immunity of the human body and build up health, and there is certain ease constipation to lead to
Just function.Easily absorb, it is without any side effects to human body, there are antibacterial and anti-inflammation functions.
Aloe full leaf ovendry power is selected 2 years or more ripe Aloe Barbadensis Miller fresh leafs of growth, is carried out after drying ultra-fine
Crushing and processing are made, and relax bowel, liver-protecting and alcoholism-relieving, beautifying face and moistering lotion and other effects.
Radix Glycyrrhizae, alias：Licorice, unpeeled RADIX GLYCYRRHIZAE, ural licorice root tip, sweet tea root, lantern, honeywort, state is old, Herba Hedyotis cantonensis, powder are careless, honey is sweet,
It is mild-natured, sweet in flavor, return 12 warps.There are removing toxic substances, eliminating the phlegm, analgesic, spasmolysis so that the pharmacological actions such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae tonifying spleen
QI invigorating grows cough moistening lung, emergency removing toxic substances, hundred medicines of reconciliation.Clinical practice point " raw to use " is not with " honey is processed ".It is raw to be swollen with curing mainly throat
Bitterly, pain subcutaneous ulcer sore, gastrointestinal ulceration and antidote poison, food poisoning etc.；Honey toast cures mainly spleen and stomach function decline, and big loose stool is thin, weary
Power fever and cough, palpitaition etc..There is following and effect：1. antiacid, Radix Glycyrrhizae has similar cortex hormone of aadrenaline sample to make
With having inhibiting effect to gastroxia caused by histamine；And there is antiacid and alleviation gastrointestinal smooth muscle spasm effect；2. town
Cough, licoflavone, extract of licorice root and enoxolone have apparent antitussive effect；Phlegm-dispelling functions are also more significant, action intensity
For glycyrrhizic acid>Licoflavone>Extract of licorice root；3. anti-inflammatory, antiallergy, Radix Glycyrrhizae is also anti-inflammatory, anti-allergic effects, can protect inflammation
Throat and tunica mucosa tracheae, extract of licorice root and glycyrrhizic acid have certain poisonous substances the detoxication of similar glucuronic acid；4. balance female
Property body in hormone, the symptom that Radix Glycyrrhizae is commonly used to treat with climacteric and comes is a kind of similar because containing glycyrrhizin in Radix Glycyrrhizae
The compound of hormone, it helps to balance the hormone-content in women body；5. anti-curing oncoma, the hypo acid contained by Radix Glycyrrhizae can block cause
The effect of cancer object induced tumor growth.
Cassia seed, alias：Cassia occidentalis, sheep are bright, goat's horn, horseshoe Cassia, go back pupil, bullshit beans, false mung bean, horseshoe, thousand
In light, celery certainly, swordweed.The salty hardship of taste, it is cool in nature；Return liver, courage, kidney channel.Expelling wind and clearing away heat, detoxification and promoting urination.Main anemopyretic cold, influenza,
Acute conjunctivitis, jaundice with damp-heat pathogen, acute and chronic nephritis, under, scrofula, sore carbuncle furuncle, mastitis.There is following and effect；
1. improving eyesight for diseases such as red eye, swell pain, the more tears of photophobia, optic atrophies, alleviates the diseases such as red eye, swell pain, the more tears of photophobia, is in irascibility
It disturbs or the diseases such as wind-heat；2. preventing optic atrophy, optic atrophy, mostly as caused by kidney deficiency and liver, cassia seed clears liver and improving eyesight, often
It is equal with tonic liver renal drug such as SEMEN ASTRAGALI COMPLANATI, the fruit of glossy privet, the fruit of Chinese wolfberry, Radix Rehmanniae and uses, controls optic atrophy；3. relieving asthma, cholagogic, guarantor
Liver, decompression, contained rheum emodin, Rhein have to human body relieving asthma, cholagogic, liver protection, antihypertensive effect, and have certain antibacterial, anti-inflammatory make
With；4. blood pressure lowering, modern clinic treats hyperlipidemia with cassia seed, cassia seed decocting or tablets is made；5. cardiac stimulant, contained
Emodin monoglucoside, emodin anthrone, Physcion, having reduces serum cholesterol and cardiac effect；6. it relaxes bowel.
The nutritive value of cassia seed：Cassia seed is in addition to containing carbohydrate, protein, fat, also containing steroidal compounds, Chrysophanol, rheum emodin
Deng trace elements iron, zinc, manganese, copper, nickel, cobalt, molybdenum etc. also necessary to human body.Cassia seed element has a- hydroxyls, can be with metal element
Complex compound is synthesized, is had a significant impact to metallic element absorption.In addition, civil common cassia seed stir-bake to yellowish end, on behalf of the tea, have prevention and
Treat the healthcare function of disease.
Semen Coicis, alias：SEMEN COICIS, Job's tears, coix seed, maize rice, the seed of jog's tears, myotonin, ditch rice, the seed of jog's tears, adlay.Nature and flavor
It is sweet it is light be slightly cold, have inducing diuresis for removing edema, invigorating spleen to remove dampness, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus and other effects, be common damp-clearing drug.Have
Following effect and effect：1. cancer-resisting, contained by selenium element can effectively inhibit the breeding of cancer cell, available for clouds cancer, son
The auxiliary treatment of cervical carcinoma, Healthy People often eat Semen Coicis, and body can be made spry and light, reduce tumor invasion probability.Especially with the insufficiency of the spleen with overabundance of dampness
It is more suitable that tumor in digestive tract and phlegm heat hold wet lung cancer under the arm, and in Japan, Semen Coicis is seen as typical " anticancer food ", moreover it is possible to be mitigated
The toxic side effect of tumor patient chemicotherapy；2. strengthening the spleen and stomach promotees metabolism, Semen Coicis is because containing multivitamin and minerals, there is promotion
Metabolism and the effect for reducing stomach and intestine burden, can be used as in disease or the help food of weak patients after being ill, often edible Semen Coicis
Food is also effective to diseases such as chronic enteritis, indigestions；3. it is a kind of containing certain vitamin E in Semen Coicis skin whitening
Beauty food, often feeding can keep human skin gloss fine and smooth, eliminate acne, color spot, improve the colour of skin；And it is for by virus
Wart caused by infection etc. has certain therapeutic effect；4. clearing damp and promoting diuresis has inducing diuresis for removing edema, invigorating spleen to remove dampness, relaxing muscles and tendons eliminating impediment, heat-clearing
Apocenosis and other effects is common damp-clearing drug.
Radix Angelicae Sinensis, alias：Angelica powder, it is dry return, horse hair Radix Angelicae Sinensis, the Qin which, horse hair is returned, cloud is returned, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis.It is warm-natured, taste
Gan Xin.The thoughts of returning home, liver, the spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation.Irregular menstruation, Amenorrhea abdominal pain are controlled, abdominal mass knot gathers, collapses
Leakage；Headache due to deficiency of blood, dizziness, Impotence numbness；Intestines are dry and shit is difficult, weight after dysentery characterized by blood in the stool；Ulcer sore is stolen, injury from falling down.There is following and effect：
1. enriching blood, body hematopoiesis function, raising red blood cell, leucocyte and content of hemoglobin can be remarkably promoted；2. Adjust-blood lipid inhibits blood
Platelet agglomerates, antithrombotic, adjusts blood fat；3. blood pressure lowering resists myocardial ischemia, arrhythmia cordis, blood vessel is expanded, is reduced blood pressure；4. increase
Strong immunity enhances immune, anti-inflammatory, liver protection, radioresistance, anti-oxidant and removing free radical etc..The nutritive value of Radix Angelicae Sinensis：Radix Angelicae Sinensis master
Contain sucrose, a variety of amino acid, volatile oil and n-butene, lactone, niacin, ferulic acid and half terpenoid, also containing dimension
Raw element A, vitamin E, volatile oil, arginine and several mineral materials.
The beneficial effects of the invention are as follows：The invention discloses a kind of aloetic anti-acne drug and preparation method thereof, the medicines
Object being capable of effectively anti-acne, ecchymose removing, antibacterial anti-inflammatory.Especially to acne, acne, papule epifolliculitis, seborrheic dermatitis, pachylosis,
Complexion caused by color spot, freckle, abdominal distension, apocleisis, insomnia, endocrine disorder is withered and yellow remarkable efficacy.It can effectively exclude body simultaneously
Endotoxin repairs scar, strengthen immunity.
Specific embodiment
Embodiment 1：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
8Kg, 18 Kg of aloe full leaf ovendry power, 2 Kg of Radix Glycyrrhizae, 8 Kg of cassia seed, 8 Kg of Semen Coicis, 2 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 8Kg, aloe full leaf
18 Kg of ovendry power, 2 Kg of Radix Glycyrrhizae, 8 Kg of cassia seed, 8 Kg of Semen Coicis, 2 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 2：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder 19
Kg, 37 Kg of aloe full leaf ovendry power, 8 Kg of Radix Glycyrrhizae, 17 Kg of cassia seed, 16 Kg of Semen Coicis, 6 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：19 Kg of aloe full leaf freeze-dried powder, aloe are complete
37 Kg of leaf ovendry power, 8 Kg of Radix Glycyrrhizae, 17 Kg of cassia seed, 16 Kg of Semen Coicis, 6 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 3：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
8Kg, 37 Kg of aloe full leaf ovendry power, 2 Kg of Radix Glycyrrhizae, 17 Kg of cassia seed, 8 Kg of Semen Coicis, 6 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 8Kg, aloe full leaf
37 Kg of ovendry power, 2 Kg of Radix Glycyrrhizae, 17 Kg of cassia seed, 8 Kg of Semen Coicis, 6 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 4：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
10Kg, 20 Kg of aloe full leaf ovendry power, 3 Kg of Radix Glycyrrhizae, 10 Kg of cassia seed, 10 Kg of Semen Coicis, 3 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 10Kg, aloe are complete
20 Kg of leaf ovendry power, 3 Kg of Radix Glycyrrhizae, 10 Kg of cassia seed, 10 Kg of Semen Coicis, 3 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 5：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
15Kg, 35 Kg of aloe full leaf ovendry power, 5 Kg of Radix Glycyrrhizae, 15 Kg of cassia seed, 15 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 15Kg, aloe are complete
35 Kg of leaf ovendry power, 5 Kg of Radix Glycyrrhizae, 15 Kg of cassia seed, 15 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 6：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
10Kg, 35 Kg of aloe full leaf ovendry power, 3 Kg of Radix Glycyrrhizae, 15 Kg of cassia seed, 10 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 10Kg, aloe are complete
35 Kg of leaf ovendry power, 3 Kg of Radix Glycyrrhizae, 15 Kg of cassia seed, 10 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Embodiment 7：A kind of aloetic anti-acne drug, is grouped as by each group of following weight：Aloe full leaf freeze-dried powder
12Kg, 28 Kg of aloe full leaf ovendry power, 4 Kg of Radix Glycyrrhizae, 13 Kg of cassia seed, 12 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis.
A kind of preparation method of aloetic anti-acne drug, includes the following steps：
A, picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and
Radix Angelicae Sinensis medicinal material, and powdering is ground to medicinal material, it is weighed by following weight：Aloe full leaf freeze-dried powder 12Kg, aloe are complete
28 Kg of leaf ovendry power, 4 Kg of Radix Glycyrrhizae, 13 Kg of cassia seed, 12 Kg of Semen Coicis, 5 Kg of Radix Angelicae Sinensis；
B, mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
C, it fills：The material after being granulated in step B is filled in capsule using capsule filler；
D, bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
E, it packs：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
Most preferred formula is the formula in embodiment 7.
Investigation and analysis：
This investigation:
1st, this investigation 112 patient of case, patient symptom includes acne, acne, papule epifolliculitis and seborrheic dermatitis etc., main
Symptom is wanted as acne and acne, wherein 72 people of male patient, 40 people of female patient, the age, average age was between 14-30 Sui
22 years old, patient is randomly divided into 7 groups by statistics, every group is 16 people.
2nd, therapeutic scheme
First group is treated using the drug of embodiment 1；
Second group is treated using the drug of embodiment 2；
Third group is treated using the drug of embodiment 3；
4th group is treated using the drug of embodiment 4；
5th group is treated using the drug of embodiment 5；
6th group is treated using the drug of embodiment 6；
7th group is treated using the drug of embodiment 7.
3rd, efficacy assessment standard：
It cures：Complete recession 100%, no clinical symptoms at acne.
It improves：Subside about 80% at acne, there is slight pain to itch symptom.
It takes effect：Recession about 30% at acne, aching symptom of itching has minor responses.
In vain：Quantity without recession sign or even acne at acne increases, and pain is itched unbearably.
Recurrence：It cures in 6 months without clinical symptoms.
4th, the effect after treating 15 days：
According to the investigation statistics of above table, a kind of aloetic anti-acne drug provided by the invention is quick, treatment effect
Fruit is good, and recurrence rate is low, wherein in the drug of 7 embodiments provided by the invention, the drug of embodiment 7 is optimum formula, is cured
Rate highest, recurrence rate 0.
Clinical case：
Case 1：Zhang, man, 30 years old, face had acne and acne to have 3 years, and recurrence is occurred as soon as after western medicine, after drug withdrawal
Symptom began to use the drug of the embodiment of the present invention 7 to be treated, 2 times a day, 2 tablets each time, continuously on January 28th, 2016
After taking 15 days, the acne and acne of patient facial region subside completely, without rebound phenomenon after drug withdrawal, so far still without any relapse indications.
Case 2：Zhao, female, 18 years old, in June, 2015, face started long whelk, was implemented using the present invention in March, 2016
The drug of example 7 is treated, and 2 times a day, two every time, is continuously taken 13 days, and the whelk of patient facial region subsides completely, is continued
It takes half a month, acne print is significantly desalinated, without any relapse indications after drug withdrawal.
Claims (4)
1. a kind of aloetic anti-acne drug, it is characterised in that：It is grouped as by each group of following parts by weight：Aloe full leaf is lyophilized
8-19 parts of powder, 18-37 parts of aloe full leaf ovendry power, 2-8 parts of Radix Glycyrrhizae, 8-17 parts of cassia seed, 8-16 parts of Semen Coicis, 2-6 parts of Radix Angelicae Sinensis.
2. a kind of aloetic anti-acne drug according to claim 1, it is characterised in that：By each group of following parts by weight
It is grouped as：10-15 parts of aloe full leaf freeze-dried powder, 20-35 parts of aloe full leaf ovendry power, 3-5 parts of Radix Glycyrrhizae, 10-15 parts of cassia seed, the heart of a lotus seed
Rice 10-15 parts, 3-5 parts of Radix Angelicae Sinensis.
3. a kind of aloetic anti-acne drug according to claim 1, it is characterised in that：By each group of following parts by weight
It is grouped as：12 parts of aloe full leaf freeze-dried powder, 28 parts of aloe full leaf ovendry power, 4 parts of Radix Glycyrrhizae, 13 parts of cassia seed, 12 parts of Semen Coicis, Radix Angelicae Sinensis
5 parts.
4. a kind of a kind of preparation method of aloetic anti-acne drug according to claim 1, it is characterised in that；Including with
Lower step：
Picking of raw material：The aloe full leaf freeze-dried powder of selection check qualification, aloe full leaf ovendry power, Radix Glycyrrhizae, cassia seed, Semen Coicis and work as
Return medicinal material, and powdering is ground to medicinal material, parts by weight as described in claim 1 are weighed；
Mixing compounding：Each component in step A is sufficiently mixed, and mixed component is granulated；
Filling：The material after being granulated in step B is filled in capsule using capsule filler；
Bubble-cap pressing plate：The capsule in step C is closed using bubble-cap trigger squeeze；
Packaging：The capsule pressing plate mounted box that will be made in step D, vanning, outbound after inspection.
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| CN201810193532.XA CN108186937A (en) | 2018-03-09 | 2018-03-09 | A kind of aloetic anti-acne drug and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109646383A (en) * | 2019-01-21 | 2019-04-19 | 秋臣化妆品有限公司 | A kind of autumn minister aloe gel and preparation method thereof |
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| CN106333913A (en) * | 2016-07-01 | 2017-01-18 | 高国龙 | Traditional Chinese medicinal composition for removing spots and acnes, and preparation method thereof |
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| JP2000044997A (en) * | 1998-07-27 | 2000-02-15 | Kenki Boku | Skin care soap |
| CN106668629A (en) * | 2015-11-11 | 2017-05-17 | 王国成 | Traditional Chinese recipe for treating whelk |
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Application publication date: 20180622 |