CN108126136A - A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating chronic pelvic inflammatory disease according to the understanding mechanism of Chinese traditional treatment chronic pelvic inflammatory disease, each component and its mass parts ratio of the drug are as follows：30~100g of pangolin, 100~260g of honeysuckle, 30~100g of radix scutellariae, melon wither 100~160g, 100~350g of dandelion, 150~350g of Chinese violet, 150~300g of Fructus Forsythiae, 30~120g of spina gleditsiae, 60~150g of the radix paeoniae rubrathe, 80~180g of Radix Angelicae Sinensis, 100~160g of Caulis Spatholobi, 50~120g of trigone, 60~100g of moutan bark, 50~120g of Rhizoma Chuanxiong, rhizoma cyperi（Vinegar system）50~120g, 80~160g of peach kernel, 80~160g of corydalis tuber, 80~160g of the seed of cowherb, 60~160g of field pennycress, 100~160g of Sargent gloryvine；Drug provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating chronic pelvic inflammatory disease, particularly The capsule medicine used for chronic basin osteitis patient and the field of preparation method.

Background technology

Doctor thinks：Chronic pelvic inflammatory disease refers to female internal genital organs and its surrounding connective tissue, the chronic inflammation of pelvic peritoneum Disease.It does not often cure thoroughly for acute pelvitis of pelvic cavity, in the case where patient's constitution is poor, the course of disease of acute pelvitis of pelvic cavity can delay and instead Recurrence is made, and causes chronic pelvic inflammatory disease；But also can be without acute pelvic inflammation medical history process, the defeated ovum as caused by chlamydia trachomatis infection Guan Yan.The chronic pelvic inflammatory disease state of an illness is more obstinate, can lead to paramenia, leucorrhea increasing, waist abdomen pain and infertile etc..

Clinical manifestation：

1. symptom

（1）Chronic pelvic pain, chronic inflammation formed cicatricial adhesion and pelvic congestion, often cause lower abdomen falling inflation, pain and Lumbosacral region is ached.Often aggravate after tired, standing, sexual intercourse for a long time and before and after menstruation.Severe one influences work.

（2）Infertile and ectopic pregnancy, fallopian tube adhesion obstruction can cause infertile and ectopic pregnancy.Infertile hair after acute pelvitis of pelvic cavity Raw rate is 20%~30%.And with the development of the state of an illness, ascendant trend is presented in incidence of infertility.

（3）Menoxenia, endometritis often have the more dysmenorrhoeas of leucorrhea increasing, paramenia, blood volume, dyspareunia； Pelvic congestion can cause menorrhagia；Ovarian function can cause menstrual disorder when damaging.

（4）Constitutional symptom, more unobvious, only low-heat, susceptible tired sometimes.Since course of disease time is longer, some patientss It may occur in which neurasthenia symptom, such as lassitude, whole body discomfort, insomnia.When patient resists force difference, acute or sub- urgency is tended to have Property breaking-out.

2. sign

General signs：The more hypsokinesis in uterus, limitation of activity or adhesion are fixed；Or fallopian tubal thickening tenderness；Or touch capsule mass；Or Sheet thickens tenderness etc. by uterus.

（1）If endometritis, uterus increase, tenderness；If salpingitis, then contacted in uterus one or both sides and be in The thickening fallopian tubal of rope strip, and have mild tenderness.

（2）If hydrosalpinx or tubo-ovarian cyst, then Cystic lesions are touched in pelvic cavity one or both sides, activity It is mostly limited.

（3）During if connective tissue inflammation of pelvic cavity, uterus is often in retroversioflexion, and limitation of activity or adhesion are fixed, uterus side Or both sides have sheet to thicken, tenderness, the normal thickening of uterosacral ligament is hardened, and has tenderness.

So, it is those skilled in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat chronic basin osteitis The problem of urgently to be resolved.

Invention content

With the continuous development of China's traditional Chinese medicine, on chronic basin osteitis is treated, people gradually appreciate the traditional Chinese medical science The advantages for the treatment of chronic basin osteitis, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing west The present situation for treating chronic basin osteitis is cured, the purpose of the invention is to provide a kind of capsule medicine for treating chronic pelvic inflammatory disease, To solve the problems, such as that chronic basin osteitis patient gets well early.The drug is using common Chinese medicine as raw material, is closed by selecting Drug and the mass parts ratio of reason can effectively treat above-mentioned chronic pelvic inflammatory disease one and demonstrate,prove.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：It provides and a kind of treats chronic pelvic inflammatory disease Capsule medicine and preparation method, which is characterized in that each component and mass parts of the drug are than as follows：

30~100g of pangolin, 100~260g of honeysuckle, 30~100g of radix scutellariae, melon wither 100~160g, dandelion 100~ 350g, 150~350g of Chinese violet, 150~300g of Fructus Forsythiae, 30~120g of spina gleditsiae, 60~150g of the radix paeoniae rubrathe, Radix Angelicae Sinensis 80~ 180g, 100~160g of Caulis Spatholobi, 50~120g of trigone, 60~100g of moutan bark, 50~120g of Rhizoma Chuanxiong, rhizoma cyperi（Vinegar system）50~ 120g, 80~160g of peach kernel, 80~160g of corydalis tuber, 80~160g of the seed of cowherb, 60~160g of field pennycress, Sargent gloryvine 100~ 160g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease, which is characterized in that each group of the drug Divide and mass parts are than as follows：

36~90g of pangolin, 115~230g of honeysuckle, 36~90g of radix scutellariae, melon wither 115~140g, 115~310g of dandelion, 180~310g of Chinese violet, 180~260g of Fructus Forsythiae, 36~105g of spina gleditsiae, 70~130g of the radix paeoniae rubrathe, 90~160g of Radix Angelicae Sinensis, chicken blood 115~140g of rattan, 56~105g of trigone, 70~90g of moutan bark, 56~105g of Rhizoma Chuanxiong, rhizoma cyperi（Vinegar system）56~105g, peach kernel 90 ~140g, 90~140g of corydalis tuber, 90~140g of the seed of cowherb, 70~140g of field pennycress, 115~140g of Sargent gloryvine, auxiliary material：Micro mist Silica gel, microcrystalline cellulose and appropriate starch.

A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease, which is characterized in that each group of the drug Divide and mass parts are than as follows：

Pangolin 80g, honeysuckle 200g, radix scutellariae 80g, melon wither 120g, dandelion 280g, Chinese violet 280g, Fructus Forsythiae 230g, soap Angle thorn 95g, radix paeoniae rubrathe 118g, Radix Angelicae Sinensis 140g, Caulis Spatholobi 120g, trigone 95g, moutan bark 80g, Rhizoma Chuanxiong 95g, rhizoma cyperi（Vinegar system）95g、 Peach kernel 120g, corydalis tuber 120g, seed of cowherb 120g, field pennycress 120g, Sargent gloryvine 120g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.

A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease, which is characterized in that the method includes as follows Step is prepared：

A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, is ground into according to mass parts than altogether（30~50 mesh）Graininess packet It decocts；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 55min, then soaked drug is put into marmite again, The cold boiling water for adding in 8~10 times of raw material Chinese medicine weight carries out first time high heat decoction, when decocting to 18min, turns slow boiling tanning 120min, leaching liquid；2. the cold boiling water for adding in 7~9 times of raw material Chinese medicine weight in the dregs of a decoction again is fried by intense fire for the second time It boils, when decocting to 15min, turns slow boiling tanning 110min, leaching liquid；3. the mixing of secondary liquid is condensed into relative density is 1.08 clear cream, it is then dry, grind with it is after disinfection to reserve；

C, the method for 1. preparing Chinese medicine capsules according to tradition after smalls sieving ground in B, adds in suitable micro mist silicon Glue, microcrystalline cellulose and starch are uniformly mixed, and are then prepared into capsule（Its capsule it is sealed after total length be 23.3mm, medicinal powder Capacity 0.4~0.5g/）, 2. then polish, sterilize, sealed packaging.

A kind of capsule medicine and preparation method for treating chronic pelvic inflammatory disease, which is characterized in that the instructions of taking is：It will The capsule medicine prepared is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2g（4）/ time, warm water delivery service （During treatment, diet is light as possible, pays attention to health, cannot temporarily have sexual intercourse）.30 days as a treatment course, 2~4 treatments of taking medicine Journey, inflammation disappear, and the disease is cured.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Pangolin, nature and flavor：Taste is salty, cold nature, has the effect of breast, anti-stain in solid under blood circulation promoting and dispersing pathogen accumulation, promoting menstruation, for treating blood stasis The diseases such as Amenorrhea, Disorder lumps in the abdomen, arthralgia pain due to rheumatism, agalactia, carbuncle swells, scrofula；

Honeysuckle, nature and flavor：It is sweet, cold, have it is clearing heat and detoxicating the effect of, for treat warm disease heating, toxic-heat and blood stasis, carbuncle swells furunculosis, Larynx numbness and multi-infection disease；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, there is the effect of clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, tocolysis, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis；

Melon withers, nature and flavor：Sweet, slight bitter is trembled with fear, and has the effect of clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation, for treating lung heat cough It coughs, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swell and ache, constipation；

Dandelion, nature and flavor：Bitter；It is sweet, cold in nature, there is the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind, for treating acute mastitis, lung carbuncle, intestines Carbuncle, mumps, boil poisonous soreness, red eye, swell pain, cold, fever, cough, abscess of throat, stomach fire, enteritis, dysentery, hepatitis, courage frighten it is scorching, Urinary tract infections, snakebite and bugbite；

Chinese violet, nature and flavor：It is cold in nature, bitter, pungent, there is the effect of clearing heat and detoxicating, cool detumescence, belong to the clear of antipyretic subordinate classification Be pyrolyzed poison, for treat the diseases such as furunculosis carbuncle swells caused by heat toxin carbuncle knot, acute mastitis, acute appendicitis, erysipelas and the hot hot eyes of liver swelling and pain, Venomous snake bite；

Fructus Forsythiae, nature and flavor：It is bitter, cool, there is the effect of heat-clearing, removing toxic substances, dissipating bind, detumescence, for treating warm, erysipelas, macula, large carbuncle Pyogenic infections, scrofula, urine leaching closes；

Spina gleditsiae, nature and flavor：It is acrid flavour, warm-natured, there is the effect of detumescence eliminating toxic, apocenosis, desinsection, for treat ulcer from the beginning of or purulence into It does not burst, controls mange leprosy outside；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapses band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, the accumulation of hernia lump in the abdomen, injury from falling down at red eye, swell pain；

Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type abdominal pain, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury；

Caulis Spatholobi, nature and flavor：It is bitter, micro-sweet, warm-natured, there is the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation, for treat it is numb in every limb, Quadriplegia, arthralgia pain due to rheumatism, women have through diseases such as uncomfortable, dysmenorrhoea, amenorrhoeas；

Trigone, nature and flavor：It is pungent, bitter, flat, there is the effect of blood-breaking, Xiao Ji Zhi Tong, for treating abdominal mass lump in the abdomen, dysmenorrhoea, hemostasis Amenorrhea, chest impediment and cardialgia, dyspepsia distending pain；

Moutan bark, nature and flavor：It is arduous, cool, be slightly cold, have heat-clearing, promoting blood circulation to remove blood stasis the effect of, for treat warm heat disease heat invading xuefen, Hair spot, germ later stage brimful of tears hot Fu Yin distributions heat, deficiency of Yin osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhoea, carbuncle sore tumefacting virus, falls at hematemesis Flutter grieved, beriberoid pyretic arthralgia；

Rhizoma Chuanxiong, nature and flavor：It is pungent, warm, there is the effect of wet promote breath and open depression, method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, lump in the abdomen abdominal pain, chest side of body thorn Bitterly, tumbling and swelling, arthralgia pain due to rheumatism；

Rhizoma cyperi（Vinegar system）, nature and flavor：Acrid flavour is slightly cold, nontoxic, has the effect of regulating the flow of vital energy Xie Yu, menstruction regulating and pain relieving, tocolysis, for treating The distending pain in hypochondrium, breast swelling, hernia pain, irregular menstruation, epigastric abdominal fullness pain, belch acid regurgitation, evil of vomitting, dysmenorrhea, uterine bleeding With under, fetal irritability；

Peach kernel, nature and flavor：Bitter sweet is put down, nontoxic, has the effect of blood-breaking row stasis of blood, moisturize laxation, for treating Amenorrhea, Disorder lumps in the abdomen, pyreticosis Store the diseases such as blood, wandering arthritis, malaria, traumatic injury, blood stasis and swelling pain, the dry constipation of blood；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, it is nontoxic, there is promoting blood circulation, dissipate the effect of stasis of blood, qi-regulating, analgesic, for treating trusted subordinate's waist and knee All pains, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury；

The seed of cowherb, nature and flavor：It is bitter, flat, there is promoting circulation of blood promoting menstruation, expedite the emergence of the effect of lower breast, healing up sore and subduing swelling, for treating women's warp Close, alactation, difficult labour, blood strangury, metal-inflicted wound bleeding, breast, activating blood circulation and reducing swelling, hemostasis lump, sore and toxic under promoting menstruation；

Field pennycress, nature and flavor：Cool in nature, acrid flavour, hardship have the effect of clearing heat and detoxicating, eliminating the phlegm apocenosis, for treating acute appendicitis, lung carbuncle, dysentery Disease, postpartum blood stasis abdominal pain, carbuncle swells furunculosis；

Sargent gloryvine, nature and flavor：It is bitter, flat, there is the effect of promoting blood circulation and removing obstruction in channels, beaten stasis, wind dispelling insecticide, for treat abdominalgia with intestinal abscess, Traumatic injury, dysmenorrhoea, pain in rheumatoid joints.

Drug of the present invention is the principle based on the chronic basin osteitis of Chinese traditional treatment, from the pathomechanism according to chronic basin osteitis and Pharmacological action is thought：With regard to chronic basin osteitis, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, to above-mentioned disease There is good therapeutic effect.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned chronic basin osteitis is prepared using the formula Medicine effect it is good, it is quick, be a good Chinese prescription, be particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating chronic pelvic inflammatory disease, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pangolin 80g, honeysuckle 200g, radix scutellariae 80g, melon wither 120g, dandelion 280g, Chinese violet 280g, Fructus Forsythiae 230g, soap Angle thorn 95g, radix paeoniae rubrathe 118g, Radix Angelicae Sinensis 140g, Caulis Spatholobi 120g, trigone 95g, moutan bark 80g, Rhizoma Chuanxiong 95g, rhizoma cyperi（Vinegar system）95g、 Peach kernel 120g, corydalis tuber 120g, seed of cowherb 120g, field pennycress 120g, Sargent gloryvine 120g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.

Embodiment 2：

A kind of capsule medicine for treating chronic pelvic inflammatory disease, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pangolin 90g, honeysuckle 230g, radix scutellariae 90g, melon wither 140g, dandelion 310g, Chinese violet 310g, Fructus Forsythiae 260g, soap Angle thorn 105g, radix paeoniae rubrathe 130g, Radix Angelicae Sinensis 160g, Caulis Spatholobi 140g, trigone 105g, moutan bark 90g, Rhizoma Chuanxiong 105g, rhizoma cyperi（Vinegar system） 105g, peach kernel 140g, corydalis tuber 140g, seed of cowherb 140g, field pennycress 140g, Sargent gloryvine 140g, auxiliary material：Superfine silica gel powder, crystallite Cellulose and appropriate starch.

Embodiment 3：

A kind of capsule medicine for treating chronic pelvic inflammatory disease, which is characterized in that each component and mass parts of the drug are such as Shown in lower：

Pangolin 100g, honeysuckle 260g, radix scutellariae 100g, melon wither 160g, dandelion 350g, Chinese violet 350g, Fructus Forsythiae 300g, Spina gleditsiae 120g, radix paeoniae rubrathe 150g, Radix Angelicae Sinensis 180g, Caulis Spatholobi 160g, trigone 120g, moutan bark 100g, Rhizoma Chuanxiong 120g, rhizoma cyperi（Vinegar System）120g, peach kernel 160g, corydalis tuber 160g, seed of cowherb 160g, field pennycress 160g, Sargent gloryvine 160g, auxiliary material：It is superfine silica gel powder, micro- Crystalline cellulose and appropriate starch.

Model case：

Through the chronic basin osteitis patient of clinical conditions totally 1170, the age is 665 of 35 years old or more, and only 505 are 35 Year is following.What the disease is cured in 1170 patients has 1007, effective 104, invalid 59.Total effective rate is up to 95%.

Claims (3)

1. a kind of capsule medicine for treating chronic pelvic inflammatory disease, which is characterized in that each component and the mass parts ratio of the drug It is as follows：

30~100g of pangolin, 100~260g of honeysuckle, 30~100g of radix scutellariae, melon wither 100~160g, dandelion 100~ 350g, 150~350g of Chinese violet, 150~300g of Fructus Forsythiae, 30~120g of spina gleditsiae, 60~150g of the radix paeoniae rubrathe, Radix Angelicae Sinensis 80~ 180g, 100~160g of Caulis Spatholobi, 50~120g of trigone, 60~100g of moutan bark, 50~120g of Rhizoma Chuanxiong, rhizoma cyperi（Vinegar system）50~ 120g, 80~160g of peach kernel, 80~160g of corydalis tuber, 80~160g of the seed of cowherb, 60~160g of field pennycress, Sargent gloryvine 100~ 160g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.

2. it is according to claim 1 treatment chronic pelvic inflammatory disease capsule medicine, which is characterized in that the drug it is each Component and mass parts are than as follows：

36~90g of pangolin, 115~230g of honeysuckle, 36~90g of radix scutellariae, melon wither 115~140g, 115~310g of dandelion, 180~310g of Chinese violet, 180~260g of Fructus Forsythiae, 36~105g of spina gleditsiae, 70~130g of the radix paeoniae rubrathe, 90~160g of Radix Angelicae Sinensis, chicken blood 115~140g of rattan, 56~105g of trigone, 70~90g of moutan bark, 56~105g of Rhizoma Chuanxiong, rhizoma cyperi（Vinegar system）56~105g, peach kernel 90 ~140g, 90~140g of corydalis tuber, 90~140g of the seed of cowherb, 70~140g of field pennycress, 115~140g of Sargent gloryvine, auxiliary material：Micro mist Silica gel, microcrystalline cellulose and appropriate starch.

3. the capsule medicine of the treatment chronic pelvic inflammatory disease according to claim 1 to 2, which is characterized in that the drug Each component and mass parts are than as follows：

Pangolin 80g, honeysuckle 200g, radix scutellariae 80g, melon wither 120g, dandelion 280g, Chinese violet 280g, Fructus Forsythiae 230g, soap Angle thorn 95g, radix paeoniae rubrathe 118g, Radix Angelicae Sinensis 140g, Caulis Spatholobi 120g, trigone 95g, moutan bark 80g, Rhizoma Chuanxiong 95g, rhizoma cyperi（Vinegar system）95g、 Peach kernel 120g, corydalis tuber 120g, seed of cowherb 120g, field pennycress 120g, Sargent gloryvine 120g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose It is appropriate with starch.