CN108096714A - A kind of mineral composition for increasing human epidermal infiltration function and its application - Google Patents

A kind of mineral composition for increasing human epidermal infiltration function and its application Download PDF

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CN108096714A
CN108096714A CN201711381872.7A CN201711381872A CN108096714A CN 108096714 A CN108096714 A CN 108096714A CN 201711381872 A CN201711381872 A CN 201711381872A CN 108096714 A CN108096714 A CN 108096714A
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magnetite
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刘华文
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/06Magnetotherapy using magnetic fields produced by permanent magnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0625Warming the body, e.g. hyperthermia treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared
    • A61N2005/066Radiation therapy using light characterised by the wavelength of light used infrared far infrared

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  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Abstract

A kind of mineral composition for increasing human epidermal infiltration function of the present invention, is made of superfines of the grain size less than the tourmaline of 6000 mesh, stone needle, magnetite, Khotan jade;And four kinds of materials of tourmaline, stone needle, magnetite, Khotan jade described in the ultra-fine mixed powder respectively account for 25%.Make full use of the far-infrared functional function that the far infrared superfine powder interaction that the superfines of tourmaline, stone needle, magnetite, Khotan jade forms is launched, the function of drug can effectively be excited, the various paste medicines for being covered in each position of human body surface is also promoted quickly and effectively to penetrate the sufferer part that the epidermis of human body and follicular permeation heal to needs simultaneously, the effect of also acting as dredging collaterals of human simultaneously more fully improves curative effect and provides technical support outside.

Description

A kind of mineral composition for increasing human epidermal infiltration function and its application
Technical field
The present invention relates to a kind of composition of mineral material, especially a kind of mineral group for increasing human epidermal infiltration function Object is closed, belongs to medicine field of physical therapy.
Background technology
In clinical medicine, externally used paste is always to cure the pharmaceutical dosage forms of some slight illness, by human skin or The body surface part of sufferer smears or pastes some paste medicaments with certain curative effect, directly by injury part or passes through Skin, hair follicle and the osmosis at specific acupuncture point of patient, in place of the active ingredient of drug is transported to sufferer, so as to reach Cure the effect of sufferer;Therefore it is always to improve the important channel of externally used paste treatment effect to improve Medicated Permeation ability.
In traditional Chinese medicine externally used paste in use, in those early years treating in traumatic injury, the externally used paste sprained usually makes With a kind of rare medicinal material such as Moschus, tiger bone.Obviously, natural musk usual in traditional Chinese medicinal external-application ointment, tiger bone etc. Main chemosmotic ingredient is always played in Chinese medicinal ointment, but the limitations such as in great shortage and ecological environmental protection due to resource are arranged It applies, these animal medicine resources for being taken from nature are substituted by artificial synthesized compound.But these are manually closed Into compound substitute traditional Chinese medicine active ingredient using effect it is not very good.
In addition, Chinese material medicine resource used by current Traditional Chinese Medicine, due to the destruction of natural environment and seizing excessively And the variation of cultivation technique, nonstandard Pesticide use when cultivating in addition make the quality of many Chinese herbal medicines also much be influenced, " the good medicine of medicinal material is better " such a requirement is truly realized so that extremely difficult.
In addition, many Western medicine paste using compound as raw material used since in recent years are used to treat various dermatitis Disease, for example:Current common ketoconazole used etc., although having to common trichophyta category, Epidermophyton, Microsporon Inhibitory action, but hardly absorbed in local topical through skin, thus while there is the effect of certain, but it is good due to lacking Good osmotic effect is being difficult to be absorbed by the skin in, therefore generally there are treatment cycle is long, affected part was healed The phenomenon that slow.
Therefore, how under the current conditions of current this drug resource, the external application of generally existing in clinical medicine is improved The therapeutic effect of paste just becomes a technical task of urgent need to resolve in contemporary clinical medicine.
The content of the invention
The purpose of the present invention:It is directed to a kind of technical side that can effectively improve externally used paste penetrating power and therapeutic effect Case longs for and reaches raising curative effect on the premise of it need not increase too many cost, do not change original prescription, drug ingedient, mitigates The effect of patient's slight illness.
Foregoing invention purpose is achieved through the following technical solutions:
This mineral composition for increasing human epidermal infiltration function is less than tourmaline, stone needle, the magnetic of 6000 mesh by grain size The ultra-fine mixed powder composition of stone, Khotan jade;And four kinds of materials of tourmaline, stone needle, magnetite, Khotan jade described in the ultra-fine mixed powder Material respectively accounts for weight ratio 25%.
The application method of this mineral composition for increasing human epidermal infiltration function is as follows:
A certain amount for the treatment of paste and the ultra-fine mixed powder of far infrared for being equivalent to paste weight 3-5% are blended in one It rises, forms the mixing paste containing far-infrared combination object;The mixing paste is then directly applied to the affected part of patient, with common Hospital gauze is wrapped up;The far ir ray launched using far-infrared material is accelerated effective ingredient and penetrates patient's epidermis And hair follicle, play the medical function in quick healing affected part.
It is further improved as to the above method, leads to emplastrum as the various non-woven fabrics based on Chinese medicine preparation, it will The paste of the ultra-fine mixed powder of suitable far infrared and Chinese medicinal ointment, which mixes, collectively forms the medicine layer on non-woven fabrics top;Profit The far ir ray launched with far-infrared material accelerates effective ingredient through patient's epidermis and hair follicle, plays quick healing The medical function in affected part.
Treatment is being pasted based on traditional herbal medicines, the far infrared ultra-fine mixed powder of herbal medicine dosage 2-5% will be accounted for in Herbal medicine mixes wrapping and is used in the diseased part of patient;The far ir ray launched using far-infrared material accelerates medicine Object active ingredient penetrates patient's epidermis and hair follicle, plays the medical function in quick healing affected part.
As being further improved for this method, by grain size be less than the tourmalines of 6000 mesh, stone needle, magnetite, Khotan jade it is ultra-fine Mixed powder and the bonding material of sticky rice syrup one kind mix, and mixing slurry is attached on hospital gauze, are formed after drying remote Infrared wavelength is in 4-20um far infrared hospital gauzes;By it is various have the function for the treatment of externally used pastes directly with the far infrared Gauze is combined into one, and is then coated with body part of the gauze wrapped in patient of paste, is emitted using far-infrared material The far ir ray that goes out is accelerated effective ingredient reaching medical function through suffer from table person's skin and hair follicle.
According to the mineral composition of this increase human epidermal infiltration function of above technical scheme proposition and its user Method makes full use of the far infrared superfine powder interaction that the superfine powder mixing of tourmaline, stone needle, magnetite, Khotan jade forms to launch Far-infrared functional function, can effectively excite the function of drug, while also promote various to be covered in each position of human body surface Paste medicine quickly and effectively penetrate human body epidermis and follicular permeation in place of needing the sufferer that heals, while also act as thin The effect of logical collaterals of human, more fully improves curative effect and provides technical support outside.
Specific embodiment
The present invention is further explained with reference to embodiments, and provides the specific implementation method of the present invention.
The invention core of this multifunctional medical gauze proposed by the present invention is at 2 points:
First, the occurring source of tourmaline, stone needle, four kinds of magnetite, Khotan jade natural minerals as far ir ray is selected, not only Material is easy to get, and takes full advantage of and 4-20um Wavelength strengths are generated under the interaction of the fine powder of these four mineral materials Far ir ray, the far ir ray under the action of body surface temperature can not only play the work for expanding human epidermal hair follicle With, while can also be effectively increased the osmosis for being coated on the various ointment active ingredients of human epidermal.
Second, above-mentioned four kinds of raw mineral materials inherently belong to China's traditional Chinese medicine, when these mixtures paste and human body When, on the acupuncture point for the corresponding site for directly acting on human body using itself original pharmacological action having, inherently possess thin The effect of degrading the channel.
According to the record of China's Chinese Traditional Medicine classics:Tourmaline scientific name tourmaline therein not only itself has energy also Nervous system can be got through and promote qi-blood circulating, and radiation can be absorbed.Tourmaline has biological electro ultrafiltration simultaneously, and surface is always The 0.06mA micro-current substantially identical with human biological electricity is flowed, therefore with the work for supplementing and adjusting human biological electricity at any time With pathology current potential is allowed to recover normal, the biological electricity rule destroyed by harmful radiations such as electromagnetic waves is allowed to recover normal, so as to play Sports health-care effect.
Stone needle therein is a kind of can to send the natural of many far ir rays beneficial to human body and ultrasonic pulse Ore medically plays an important role of to promote microcirculation in human body.
Magnetite is the magnetite ore of oxide-based mineral spinelle family, is thought in China's Chinese Traditional Medicine:Magnetite Have it is sweet in flavor, mild-natured, return liver and kidney channel;With calming the liver, hearing-improing and eyesight improving;The effect of tranquillizing the mind by relieving convulsion, gas of receiving is relievingd asthma, cure mainly liver-yang Dizziness, insomnia of palpitating with fear, blurred vision ocular, Hiccough and deaf and kidney deficiency breathe heavily inverse effect.
Containing 20 various active minerals in Khotan jade, think in Compendium of Materia Medica it have store essence, repose, avoid evil spirits it is relieving convulsion The effect of, available for soul is pacified, dredge the effect of blood vessels flexibilizing tendon and strengthening bone.
Therefore, when the fine powder that the mixture of above-mentioned four kinds of raw mineral materials is formed being directly incorporated into various medicinal paste, on The far ir ray for stating the 4-20um Wavelength strengths that the interaction of mixed mineral powder generates directly acts on the corresponding site of human body On.Both the high efficiency for the active ingredient of above-mentioned external-applied ointment penetrated into human epidermal, and cured affected part and provide and quickly and effectively lead to Road, and by the meridian theory of the foundation Traditional Chinese Medicine with four kinds of raw mineral materials, them is made to play spy by means of channels and collaterals passage Some pharmacological actions.
This mineral composition for increasing human epidermal infiltration function is less than tourmaline, stone needle, the magnetic of 6000 mesh by grain size The ultra-fine mixed powder composition of stone, Khotan jade;And four kinds of materials of tourmaline, stone needle, magnetite, Khotan jade described in the ultra-fine mixed powder Material respectively accounts for 25%.
The application method of this mineral composition for increasing human epidermal infiltration function is as follows:
A certain amount for the treatment of paste and the ultra-fine mixed powder of far infrared for being equivalent to paste weight 3-5% are blended in one It rises, forms the mixing paste containing far-infrared combination object;The mixing paste is then directly applied to the affected part of patient, with common Hospital gauze is wrapped up;The far ir ray launched using far-infrared material is accelerated effective ingredient and penetrates patient's epidermis And hair follicle, play the medical function in quick healing affected part.
It is further improved as to the above method, it, will be appropriate as the various non-woven fabrics patches based on Chinese medicine preparation The ultra-fine mixed powder of far infrared and the paste of Chinese medicinal ointment mix and collectively form the medicine layer on non-woven fabrics top;Using remote The far ir ray that infra-red material is launched accelerates effective ingredient through patient's epidermis and hair follicle, plays quick healing affected part Medical function.
Pasting treatment based on traditional herbal medicines, will account for the ultra-fine mixed powders of far infrared of herbal medicine dosage 2-5% amounts with Chinese herbal medicine mixes wrapping and is used in the diseased part of patient;The far ir ray launched using far-infrared material is accelerated Effective ingredient penetrates patient's epidermis and hair follicle, plays the medical function in quick healing affected part.
As being further improved for this method, by grain size be less than the tourmalines of 6000 mesh, stone needle, magnetite, Khotan jade it is ultra-fine Mixed powder and the bonding material of sticky rice syrup one kind mix, and mixing slurry is attached on hospital gauze, are formed after drying remote Infrared wavelength is in 4-20um far infrared hospital gauzes;By it is various have the function for the treatment of externally used pastes directly with the far infrared Gauze is combined into one, and is then coated with body part of the gauze wrapped in patient of paste, is emitted using far-infrared material The far ir ray that goes out is accelerated effective ingredient reaching medical function through suffer from table person's skin and hair follicle.
The present inventor shows that this multifunctional medical gauze not only has original common doctor through up to a hundred person-times of actual use It is penetrated with gauze for the function of wrapping while using the far infrared that the wide cut degree far-infrared material coated on gauze body is launched Line plays certain physiotherapy function through collaterals of human, and improves various liniments by the excitation of far ir ray Osmosis;The outer therapeutic effect for improving external used medicine provides fabulous technical support.
Description of the drawings
Fig. 1 relaxes so-and-so foot's state diagram for psoriatic, and wherein left photo is original graph, and right photograph is addition ore deposit Design sketch (embodiment 1) after compositions;
Fig. 2 is so-and-so the buttocks state diagram of psoriatic's chapter, and wherein left photo is original graph, and right photograph is addition ore deposit Design sketch (embodiment 2) after compositions;
Fig. 3 is so-and-so state diagram of female patient chapter, and wherein left photo is original graph, and right photograph is addition mineral group Close the design sketch (embodiment 3) after object;
Fig. 4 is so-and-so the chest state diagram of blood patients with measles chapter, and wherein left photo is original graph, and right photograph is addition ore deposit Design sketch (embodiment 4) after compositions.
Embodiment 1 (see attached drawing 1)
Patient relaxes so-and-so, people from autonomous region of Xiangxi Tujia, 80 years old age.
The patient suffers from Psoriatic skin disease and very itches incomparably for more than 20 years, and a variety of medicines is selected never to cure.It is introduced through someone Or the ketoconazole ointment for the treatment of skin tinea is selected, the far infrared of the present inventor's offer is simply provided in the ketoconazole ointment kind Superfine powder.Begin to use from June 15th, 2017, use on July 28th, 2017 always intermittently, used unconsciously once opening There must be the sensation itched, feel that psoriasis legs and feet portion has not itched by using present;The skin for being left with site of disease does not have also There is recovery.
The reset condition figure of right crus of diaphragm and left foot when left hand view in attached drawing 1 is diseased, the figure on right side are used originally Be with the addition of in ointment the present inventor to far infrared superfine powder after, the double-legged healing status figure after one wheat harvesting period of medication.
Embodiment 2 (see attached drawing 2)
Patient's chapter so-and-so, Hubei Wuhan Huang Po people, male, 45 years old age.
Patient is in buttocks with psoriasis, obstinate;In addition patient on hand with the tinea manuum, have the sensation itched.
From on June 30,20 days to 2017 June in 2017, upon somebody's introduction in the ketoconazole ointment of the treatment skin tinea used Medication is not just itched twice after the middle far infrared superfine powder given of addition the applicant, and the psoriasis of buttocks is just after week more than one It is good, skin effect phenomenon on hand also without.
Fig. 2 is the disease state photo figure that patient provides, wherein the figure in left side is to cure pervious buttocks state diagram;Right side The then buttocks state diagram to have fully recovered after use.
Embodiment 3
So-and-so madam of patient's chapter, Jiangsu Suqian people from Shuyang County, women.
Patient is sick with whole skin, back state photo when what is provided in attached drawing 3 is patient's skin of back onste Figure;The treatment added with far infrared superfine powder that patient was given from 29 days July -2017 years on the 15th June in 2017 using the present inventor The ketoconazole ointment of skin tinea;Right side is the rear state photo figure in back after the ointment provided using the present inventor.
Embodiment 4
Patient's chapter so-and-so, Wenzhou District of Zhejiang Province people from Cangnan, 27 years old age.
Patient is just present with erythema (see 4 left photo of attached drawing) with blood measles whole body under the high environment of temperature, diseased When itch all over, patient suffers from this disease 3 years or so, gone many hospital's degree not good.Liu Huawen is used upon somebody's introduction within 2017 The far infrared superfine powder that Mr. provides, the ketoconazole ointment for admixing treatment skin tinea are smeared together.From 3 days -2017 July in 2017 On July 12, in uses.Using effect is apparent (see 4 right photograph figure of attached drawing), has substantially got well now.
Embodiment 5
Patient's button so-and-so, Shanghai people, 63 years old age.
Patient on October 8th, 2016 when anything crops up thus right leg knee patella is caused to fracture.
Diagnosis provide two kinds of therapeutic schemes:
1st, operative treatment recovers very fast, but needs to carry out secondary steel nail to be taken to perform the operation;
2nd, expectant treatment, recovery are slower.
Sufferers themselves select Shanghai to face upward that benevolence hall is famous to hinder orthopedics expert's Shi Shi outpatient service diagnosis and treatment, make in 14 days October in 2016 With the exclusive special ointment of the outpatient service, change once within every two days.And invention was added in the ointment pasted in 18 days October in 2016 People Liu Huawen provide " the inorganic wide ripple far-infrared composite material of polycrystalline (far infrared superfine powder i.e. proposed by the present invention), has after The sensation itched significantly is warmed, is taken the photograph in further consultation on November 14 in 2016 and finds that fracture site healing is apparent when piece checks, continued Medication is pasted on December 9th, 2016 and rechecked again, and fracture site heals substantially.Doctor's suggestion can do rehabilitation training, Doctor explicitly indicates that:By the age bracket of patient, according to reason union without so fast, generally requires 5-6 months, now I two The effect of month far infrared superfine powder.
Embodiment 6 (Qizheng Tibetan Medicine cream example)
Patient XXX,
It rolls down from stair, many places is caused to dampen, covered using the Qizheng Tibetan Medicine patch bought in the market, due in ointment Powder position adhered to the far infrared hospital gauze that one layer of the applicant provides, eliminate the need for pain after two days.
According to analysis of the applicant to above-mentioned numerous patient's using effects, applicants contemplate that:Although patient still uses The usual ointment of doctor deploying, but due to be mixed with provided in the technical program by tourmaline, stone needle, magnetite, Khotan jade four The far infrared mixing material of the ultra-fine mixed powder composition of kind material composition;The far ir ray having just because of mixing material Effect not only makes the local skin that patient of a variety of skins with tinea is smeared at ointment generate burning heat sensation, cause ketoconazole medicine Efficiency is permeated to the depths of human skin;Simultaneously because these four materials belong to the traditional Chinese medical science medicinal material of tradition selection, each with one The effect of fixed defeated channels and activating collaterals, has effects that certain for the channels and collaterals for turning on human body.Exactly in the effect of above-mentioned multiple efficacies Under, conventional use of common drug is made to have reached the peculiar curative effect to get twice the result with half the effort.
It the above is only the basic introduction for the present invention that the applicant provides according to technical solution and embodiment, do not represent this The whole of invention.The technical staff of any industry does not possess substantial improvements according to what the basic intention of the present invention was made, It should be regarded as the protection model for belonging to the present invention.

Claims (5)

1. a kind of mineral composition for increasing human epidermal infiltration function, by grain size be less than the tourmalines of 6000 mesh, stone needle, magnetite, The superfines composition of Khotan jade;And four kinds of materials of tourmaline, stone needle, magnetite, Khotan jade described in the ultra-fine mixed powder are each Account for weight ratio 25%.
2. the application method for increasing the mineral composition of human epidermal infiltration function as described in claim 1 is as follows:
A certain amount for the treatment of paste is accelerated with being equivalent to the far ir ray that paste weight is launched using far infrared gauze By effective ingredient through patient's epidermis and hair follicle, reach medical function.
3. the application method for increasing the mineral composition of human epidermal infiltration function as described in claim 1 is as follows:
The paste of the Separate Fine-grained Minerals composition and Chinese medicinal ointment that account for Chinese medicinal ointment 2-5% amounts is mixed and collectively forms rubber The medicine layer on layer top;The far ir ray launched using far-infrared material is accelerated effective ingredient penetrating patient's epidermis And hair follicle, reach medical function.
4. the application method for increasing the mineral composition of human epidermal infiltration function as described in claim 1 is as follows:
Treatment is being pasted based on Chinese herbal medicine, the far-infrared combination object for accounting for herbal medicine dosage 2-5% amounts mixed with Chinese herbal medicine The diseased part wrapped up together in patient uses, and the far ir ray launched using far-infrared material is accelerated drug is effective Ingredient penetrates patient's epidermis and hair follicle, reaches medical function.
5. the application method for increasing the mineral composition of human epidermal infiltration function as described in claim 1 is as follows:
Grain size is less than the mixed-powder of the tourmalines of 6000 mesh, stone needle, magnetite, Khotan jade as being attached on hospital gauze, structure Into far infrared wavelength in 4-20um far infrared hospital gauzes;By the various externally used pastes with treatment directly with it is described remote Infrared gauze is combined into one, and is then coated with body part of the gauze wrapped in patient of paste, utilizes far infrared gauze On the far ir ray launched accelerate effective ingredient reaching medical function through patient's epidermis and hair follicle.
CN201711381872.7A 2017-12-20 2017-12-20 A kind of mineral composition for increasing human epidermal infiltration function and its application Pending CN108096714A (en)

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CN109550154A (en) * 2017-12-20 2019-04-02 刘华文 A kind of minerals as traditional Chinese medicine composition can increase human epidermal infiltration function and its application
CN110075417A (en) * 2019-04-02 2019-08-02 章国雄 A kind of mineral composition increasing human epidermal penetrating power
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Publication number Priority date Publication date Assignee Title
CN109550154A (en) * 2017-12-20 2019-04-02 刘华文 A kind of minerals as traditional Chinese medicine composition can increase human epidermal infiltration function and its application
CN110075417A (en) * 2019-04-02 2019-08-02 章国雄 A kind of mineral composition increasing human epidermal penetrating power
CN112891754A (en) * 2019-11-18 2021-06-04 上海嘉巷新材料科技有限公司 Terahertz wave inorganic composite environment-friendly material and application thereof
CN115400047A (en) * 2021-05-28 2022-11-29 和也健康科技有限公司 Facial mask with effects of regulating, calming and soothing nerves

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Application publication date: 20180601