CN108061963A - Ultraluminescence and the optical system of the more performance high-resolution dermoscopies of polarised light - Google Patents

Ultraluminescence and the optical system of the more performance high-resolution dermoscopies of polarised light Download PDF

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Publication number
CN108061963A
CN108061963A CN201810044774.2A CN201810044774A CN108061963A CN 108061963 A CN108061963 A CN 108061963A CN 201810044774 A CN201810044774 A CN 201810044774A CN 108061963 A CN108061963 A CN 108061963A
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lens
optical system
ultraluminescence
resolution
dermoscopies
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CN108061963B (en
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冯波
高兴华
曹铁军
齐瑞群
陈洪铎
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Liaoning Yan Yang Medical Equipment Co Ltd
Beijing Yan Yang High Tech Medical Technology Co Ltd
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Liaoning Yan Yang Medical Equipment Co Ltd
Beijing Yan Yang High Tech Medical Technology Co Ltd
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/0012Surgical microscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B13/00Optical objectives specially designed for the purposes specified below
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/02Objectives

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Lenses (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The invention discloses a kind of Ultraluminescence and the optical systems of the more performance high-resolution dermoscopies of polarised light, including the first lens, the second lens, the 3rd lens, the first lens, the second lens, the 3rd lens are set by the order of the image space from the object space of the optical system to the optical system;First lens are negative balsaming lens, and the first lens object side surface and the first lens image interface are spill, and the effect of the first lens is correction optical system correction spherical aberration, the cut-off of its material selection ultraviolet light, and preliminary removal is to the ultraviolet light of human eye injury;Second lens are positive lens, and the effects of the second lens is to correct fully and completely remove the ultraviolet light for having human eye injury after the negative spherical aberration of optical system, plated film, filter ultraviolet and infrared light;3rd lens are positive balsaming lens, and the 3rd lens object side surface and the 3rd lens image interface are convex, and the effect of the 3rd lens is field lens, and image is immediately seen by optical system with eyes to meet.

Description

Ultraluminescence and the optical system of the more performance high-resolution dermoscopies of polarised light
Technical field
The invention belongs to the auxiliary examination of dept. of dermatology and diagnostor technical fields, particularly relate to a kind of Ultraluminescence And the optical system of the more performance high-resolution dermoscopies of polarised light.
Background technology
Since the refraction coefficient of keratoderma is different from air, the light considerable part of skin surface is irradiated to by cutin Layer is reflected, and separately has part to be absorbed for skin, only penetrates skin by refraction on a small quantity, therefore usual way is difficult to observe by The deep structure of skin.
Dermoscopy is also known as epidermis light transmission microscope, is that one kind observes the following fine structure of skin surface by image capture instrument Diagnosed with the non-invasive fibre image of pigment, the Medical Devices of quantitative analysis and management, it can be directly observed epidermis lower part, The sightless structure and features of the naked eyes such as the connection of table corium, papillaris pars and reticular layer of corium, these features and histopathology Variation has special and relatively unambiguous correspondence and clinical meaning, is carried out according to these correspondences and feature dermopathic Monitoring and diagnosis.As the clinically screening of many diseases and diagnostic tool, dermoscopy has that not damaged, diagnosis is rapid, price The advantages that cheap, there is good development prospect, application is also more and more common and extensive.
In addition to the defects of dermoscopy is on there are light path used at present, due to eyeglass it is not inaccurate enough caused by difference pair Diagnosis effect impacts, and extra ultraviolet light also has certain injury to the eyes of user.
Therefore, the prior art needs to improve, and researches and develops a kind of Ultraluminescence and the more performance high-resolution dermoscopies of polarised light Optical System Design is extremely urgent, to improve image quality, reduces application risk, improves skin disease diagnosis efficiency and accurate Rate.
The content of the invention
The present invention addresses the above problem, makes up existing deficiency, provides a kind of Ultraluminescence and polarised light is more The optical system of performance high-resolution dermoscopy;The present invention can improve image quality, reduce application risk, improve skin disease and examine Disconnected efficiency and accuracy rate.
To achieve the above object, the present invention adopts the following technical scheme that.
A kind of Ultraluminescence of the present invention and the optical system of the more performance high-resolution dermoscopies of polarised light, it is characterised in that: Including the first lens, the second lens, the 3rd lens, first lens, the second lens, the 3rd lens are pressed from the optical system The order of the object space of system to the image space of the optical system is set.
First lens are negative balsaming lens, first lens engaged with right end lens by left end lens and Into, and intermediate cemented surface is formed with, the first lens object side surface and the first lens image interface are spill, first lens Effect be correction optical system correction spherical aberration, the cut-off of its material selection ultraviolet light, preliminary removal is to the ultraviolet light of human eye injury.
Second lens are positive lens, and the second lens object side surface is plane, and the second lens image interface is convex, The effect of second lens is to correct fully and completely to remove after the negative spherical aberration of optical system, plated film to have wound to human eye Harmful ultraviolet light filters ultraviolet and infrared light.
3rd lens are positive balsaming lens, and the 3rd lens object side surface and the 3rd lens image interface are convex Shape, the effect of the 3rd lens is field lens, and image is immediately seen by optical system with eyes to meet.
As a preferred embodiment of the present invention, the radius of the first lens object side surface is 13mm, intermediate cemented surface Radius for 70.924mm, the radius of the first lens image interface is 44.710mm.
As another preferred embodiment of the present invention, the center thicknesses of the left end lens is 3.0mm, in right end lens Heart thickness is 3.0mm.
As another preferred embodiment of the present invention, the radius of the second lens image interface is 21.5799mm, second The radius of lens object side surface is infinity.
Further, plated film on the second lens object side surface;Plated film meets ultraviolet band cut-off, it is seen that light 480- 650nm high is saturating, infrared band cut-off.
As another preferred embodiment of the present invention, the radius of the 3rd lens object side surface is 25.898mm, the 3rd The radius of lens image interface is 61.8mm, and the center thickness of the 3rd lens is 4.0mm.
As another preferred embodiment of the present invention, the refractive index of the left end lens material of first lens is in 1.4- Within 1.6, dispersion is within 70-75, and within 1.8-1.95, dispersion exists the refractive index of the right end lens material of the first lens Within 17-20.
As another preferred embodiment of the present invention, the refractive index of the second Lens material 1.6-1.75 it Interior, dispersion is within 48-50.
As another preferred embodiment of the present invention, the refractive index of the 3rd Lens material 1.65-1.75 it Interior, dispersion is within 50-60.
As another preferred embodiment of the present invention, the cut-off resolution ratio of the optical system is 60lp/mm.
Specifically, the object space is skin surface to be detected, and the image space is emergent pupil.
The composition form of the focal power of optical system of the present invention is "-", "+", "+".
The optical system of the present invention meets following four situation observation image:1)Right eye directly observes image;2)It is connected on outside Image is observed on mobile phone or ipaid;3)The ccd output image viewing images of connection 1/2;4)Bluetooth exports image.
Advantageous effect of the present invention.
A kind of Ultraluminescence provided by the present invention and the optical system of the more performance high-resolution dermoscopies of polarised light improve Image quality, reduces application risk, improves skin disease diagnosis efficiency and accuracy rate.
Description of the drawings
In order to which technical problem solved by the invention, technical solution and advantageous effect is more clearly understood, below in conjunction with The drawings and the specific embodiments, the present invention will be described in further detail.It should be appreciated that specific embodiment party described herein Formula is only used to explain the present invention, is not intended to limit the present invention.
Fig. 1 is the whole knot of the optical system of a kind of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light Structure connection diagram.
It is marked in figure:1 is object space, and 2 be the first lens object side surface, and 3 be left end lens, and 4 be the first lens, and 5 be centre Cemented surface, 6 be right end lens, and 7 be the first lens image interface, and 8 be the second lens object side surface, and 9 be the second lens, and 10 be the Two lens image interfaces, 11 be the 3rd lens object side surface, and 12 be the 3rd lens, and 13 be the 3rd lens image interface, and 14 be picture Side.
Specific embodiment
With reference to shown in Fig. 1, the optical system of a kind of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light, It is characterized in that:Including the first lens 4, the second lens 9, the 3rd lens 12, first lens 4, the second lens the 9, the 3rd Lens 12 are set by the order of the image space from the object space of the optical system to the optical system.
First lens 4 are negative balsaming lens, and first lens 4 are engaged by left end lens 3 with right end lens 6 It forming, and is formed with intermediate cemented surface 5, the first lens object side surface 2 and the first lens image interface 7 are spill, and described The effect of one lens 4 is correction optical system correction spherical aberration, the cut-off of its material selection ultraviolet light, and preliminary removal is to human eye injury Ultraviolet light.
Second lens 9 are positive lens, and the second lens object side surface 8 is plane, and the second lens image interface 10 is Convex, the effects of second lens 9 are fully and completely removed to human eye after correcting the negative spherical aberration of optical system, plated film Eyeball has the ultraviolet light of injury, filters ultraviolet and infrared light.
3rd lens 12 are positive balsaming lens, and the 3rd lens object side surface 11 and the 3rd lens image interface 13 are For convex, the effect of the 3rd lens 12 is field lens, and image is immediately seen by optical system with eyes to meet.
The radius of the first lens object side surface 2 is 13mm, and the radius of intermediate cemented surface 5 is 70.924mm, and first thoroughly The radius of mirror image interface 7 is 44.710mm.
The center thickness of the left end lens 3 is 3.0mm, and the center thickness of right end lens 6 is 3.0mm.
The radius of the second lens image interface 10 is 21.5799mm, and the radius of the second lens object side surface 8 is infinite Greatly.
Further, plated film on the second lens object side surface 8;Plated film meets ultraviolet band cut-off, it is seen that light 480-650nm high is saturating, infrared band cut-off.
The radius of the 3rd lens object side surface 11 is 25.898mm, and the radius of the 3rd lens image interface 13 is 61.8mm, the center thickness of the 3rd lens 12 is 4.0mm.
The refractive index of 3 material of left end lens of first lens 4 is within 1.4-1.6, and dispersion is within 70-75, and The refractive index of 6 material of right end lens of one lens 4 is within 1.8-1.95, and dispersion is within 17-20.
The refractive index of second lens, 9 lens material is within 1.6-1.75, and dispersion is within 48-50.
The refractive index of 3rd lens, 12 lens material is within 1.65-1.75, and dispersion is within 50-60.
The cut-off resolution ratio of the optical system is 60lp/mm.
Specifically, the object space 1 is skin surface to be detected, and the image space 14 is emergent pupil.
The composition form of the focal power of optical system of the present invention is "-", "+", "+".
The optical system of the present invention meets following four situation observation image:1)Right eye directly observes image;2)It is connected on outside Image is observed on mobile phone or ipaid;3)The ccd output image viewing images of connection 1/2;4)Bluetooth exports image.
The theoretical foundation of institute's foundation of the present invention is:By being given birth to skin texture and composition, skin optical property and scar Rationality Quality Research, according to Stokes' theorem, the specific UV light excitation spectrum for obtaining excitation skin fluorescence peak value is 330- 385nm.Under the spectral illumination, special composition has ultraviolet light strong absorption in dermatosis tissue, so that lesion Dark space is presented in tissue area;Healthy skin can excite strong fluorescence that clear zone is presented.The ultraviolet spectra of 330-385nm can make skin Stronger fluorescence is excited, the image of obtained dermatosis tissue is apparent, details is more rich.
The majority currently researched and developed is polarized skin lens, and the mode for realizing polarised light is that polarizer is added in optical system, Its polarised light when irradiating skin surface of the characteristic of polarised light, which is absorbed by the skin, not to be reflected, therefore the spy of polari-light skin scope Property be to enter optical system almost without veiling glare, natural light imaging clearly is compared in imaging, and to be skin exist Ultraluminescence dermoscopy Under the irradiation of ultraviolet light, the structural constituent of deep skin structure sends the visible fluorescence of right eye after absorbing ultraviolet light, these The fluorescence inspired carries the information such as skin histology lesion, may determine that according to these information with diagnosis cutaneous lesions with controlling It treats.
Polarised light is with ultraviolet light as lighting source, the former is observation skin surface image, and the latter is that observation skin is deep Layer pathological tissues structure absorbs the fluoroscopic image sent after ultraviolet light, these images carry lesion group
The information knitted.
The optical system of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light, which realizes, can observe skin The clear image on skin surface, while can switch to observation deep skin pathological tissues and absorb the fluoroscopic image sent after ultraviolet light.
The optical system of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light is gone using special mode Except not by skin histology absorb ultraviolet light, due to ultraviolet light penetration depth maximum less than centimetre scope extremely, optics First second eyeglass is in addition to meeting the effect of optical system imaging correction aberration in system, while cuts down ultraviolet light, Facet coatings requirement ultraviolet band and the near infrared band of second eyeglass end, and 480-650nm wave bands are high thoroughly, and effect further includes Ultraviolet light thoroughly is filtered, ultraviolet light harms eyes when avoiding the operating personnel from directly observing skin.
The size for designing Pupil of the optical system of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light And position meets right eye and directly observes image;Outer be connected on mobile phone or ipaid observes image;The CCD output images of connection 1/2 Observe image;Bluetooth exports image.
The optical system of Ultraluminescence of the present invention and the more performance high-resolution dermoscopies of polarised light realizes natural light, polarization It can switch between light, ultraviolet light three, realize the different images that three realizes as lighting source:Natural light skin figure Picture, polarised light skin image, Ultraluminescence skin image.
It is understood that above with respect to the specific descriptions of the present invention, it is merely to illustrate the present invention and is not limited to this The described technical solution of inventive embodiments, it will be understood by those of ordinary skill in the art that, still the present invention can be carried out Modification or equivalent substitution, to reach identical technique effect;As long as meeting using needs, all protection scope of the present invention it It is interior.

Claims (10)

1. Ultraluminescence and the optical system of the more performance high-resolution dermoscopies of polarised light, it is characterised in that:Including the first lens, Second lens, the 3rd lens, first lens, the second lens, the 3rd lens are pressed from the object space of the optical system to institute The order for stating the image space of optical system is set;First lens are negative balsaming lens, and first lens are saturating by left end Mirror is engaged with right end lens, and is formed with intermediate cemented surface, and the first lens object side surface and the first lens image interface are equal For spill, the effect of first lens is correction optical system correction spherical aberration, the cut-off of its material selection ultraviolet light, is tentatively removed To the ultraviolet light of human eye injury;Second lens be positive lens, the second lens object side surface be plane, the second lens image space Surface is convex, and the effects of second lens is fully and completely removed after correcting the negative spherical aberration of optical system, plated film There is the ultraviolet light of injury to human eye, filter ultraviolet and infrared light;3rd lens be positive balsaming lens, the 3rd lens object Square surface and the 3rd lens image interface are convex, and the effect of the 3rd lens is field lens, is passed through to meet with eyes Optical system is immediately seen image;The optical system realizes can switch between natural light, polarised light, ultraviolet light three, real The different images that three realizes as lighting source are showed:Natural light skin image, polarised light skin image, Ultraluminescence skin Image.
2. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The radius of the first lens object side surface is 13mm, and the radius of intermediate cemented surface is 70.924mm, the first lens picture The radius on square surface is 44.710mm.
3. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The center thickness of the left end lens is 3.0mm, and the center thickness of right end lens is 3.0mm.
4. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The radius of the second lens image interface is 21.5799mm, and the radius of the second lens object side surface is infinity.
5. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:Plated film on the second lens object side surface;Plated film meets ultraviolet band cut-off, it is seen that and light 480-650nm high is saturating, Infrared band ends.
6. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The radius of the 3rd lens object side surface is 25.898mm, and the radius of the 3rd lens image interface is 61.8mm, the The center thickness of three lens is 4.0mm.
7. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The refractive index of the left end lens material of first lens is within 1.4-1.6, and dispersion is within 70-75, and first thoroughly The refractive index of the right end lens material of mirror is within 1.8-1.95, and dispersion is within 17-20.
8. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The refractive index of the second Lens material is within 1.6-1.75, and dispersion is within 48-50.
9. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The refractive index of the 3rd Lens material is within 1.65-1.75, and dispersion is within 50-60.
10. Ultraluminescence according to claim 1 and the optical system of the more performance high-resolution dermoscopies of polarised light, special Sign is:The cut-off resolution ratio of the optical system is 60lp/mm.
CN201810044774.2A 2018-01-17 2018-01-17 Optical system of ultraviolet fluorescence and polarized light multi-performance high-resolution dermatoscope Active CN108061963B (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000105339A (en) * 1998-09-29 2000-04-11 Olympus Optical Co Ltd Objective optical system for stereomicroscope
CN2611925Y (en) * 2003-03-11 2004-04-14 王宏鑫 Electrical switching real leather polarizing lens
US20080049220A1 (en) * 2006-08-28 2008-02-28 Federico Izzia Spectroscopic microscopy with image-driven analysis
JP2009122372A (en) * 2007-11-14 2009-06-04 Olympus Corp Ultraviolet microscope
CN201664343U (en) * 2008-11-11 2010-12-08 深圳市莫廷影像技术有限公司 Operating microscope system with angiographic function
CN204758911U (en) * 2015-08-04 2015-11-11 中山市美景光学信息有限公司 Micro - camera lens of modularization skin
CN105640506A (en) * 2016-01-22 2016-06-08 广州医软智能科技有限公司 Device and method for obtaining clear microcirculation images
CN207799224U (en) * 2018-01-17 2018-08-31 北京燕阳高科医疗技术有限公司 The optical system of Ultraluminescence and the more performance high-resolution dermoscopies of polarised light

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000105339A (en) * 1998-09-29 2000-04-11 Olympus Optical Co Ltd Objective optical system for stereomicroscope
CN2611925Y (en) * 2003-03-11 2004-04-14 王宏鑫 Electrical switching real leather polarizing lens
US20080049220A1 (en) * 2006-08-28 2008-02-28 Federico Izzia Spectroscopic microscopy with image-driven analysis
JP2009122372A (en) * 2007-11-14 2009-06-04 Olympus Corp Ultraviolet microscope
CN201664343U (en) * 2008-11-11 2010-12-08 深圳市莫廷影像技术有限公司 Operating microscope system with angiographic function
CN204758911U (en) * 2015-08-04 2015-11-11 中山市美景光学信息有限公司 Micro - camera lens of modularization skin
CN105640506A (en) * 2016-01-22 2016-06-08 广州医软智能科技有限公司 Device and method for obtaining clear microcirculation images
CN207799224U (en) * 2018-01-17 2018-08-31 北京燕阳高科医疗技术有限公司 The optical system of Ultraluminescence and the more performance high-resolution dermoscopies of polarised light

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