CN108042427A - Chinese medicine acne-eliminating cosmetic and preparation method thereof - Google Patents

Chinese medicine acne-eliminating cosmetic and preparation method thereof Download PDF

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CN108042427A
CN108042427A CN201711443721.XA CN201711443721A CN108042427A CN 108042427 A CN108042427 A CN 108042427A CN 201711443721 A CN201711443721 A CN 201711443721A CN 108042427 A CN108042427 A CN 108042427A
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parts
radix
acne
chinese
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郑明吉
王兆雷
王广伍
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Liaoning Moisten Biological Science And Technology Co Ltd
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Liaoning Moisten Biological Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of Chinese medicine acne-eliminating cosmetics and preparation method thereof.The raw material components of acne-eliminating cosmetic include 1~8 parts by weight of monkshood, 4~12 parts by weight of radix ampelopsis, 2~8 parts by weight of Chinese cassia tree, 5~10 parts by weight of the radix paeoniae rubrathe, 7~14 parts by weight of Radix Angelicae Pubescentis, 3~10 parts by weight of radix rehmanniae recen, 6~15 parts by weight of radix aconiti agrestis, 5~10 parts by weight of the bletilla striata, 7~14 parts by weight of the root of Dahurain angelica, 1~8 parts by weight of Rhizoma Et Radix Notopterygii, 3~10 parts by weight of radix scrophulariae, 7~15 parts by weight of elephant hide, 3~10 parts by weight of 5~12 parts by weight of Radix Angelicae Sinensis, 5~12 parts by weight of kuh-seng and rheum officinale.Acne-eliminating cosmetic of the present invention selects active skull cap components to make raw material, component compatibility science, safe without toxic side effect, with excellent acne-removing, it takes effect rapid and can effectively dispel acne print, it disclosure satisfy that all orders of society continuously promotes skin care item demand, realize transformation of the skin nursing from single maintenance type to skin disease prevention type, anti-aging health care type, healthy and beautiful type.

Description

Chinese medicine acne-eliminating cosmetic and preparation method thereof
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of Chinese medicine acne-eliminating cosmetic and preparation method thereof.
Background technology
Acne is being commonly called as acne, is a kind of by multifactor caused common also known as " whelk ", " dark sore " or " acne " Chronic hair follicle, sebaceous glands inflammatory dermatoses are mainly in the position that the sebaceous glands such as face, neck, shirtfront back enrich;What is had can Scar is formed, seriously affects the appearance of people, the obtaining employment of normal person, social and marriage and childbirth etc. are had an important influence on.According to statistics, exist Puberty suffered from different degrees of dark sore acne there are about 85% people.
Common prevention dark sore acne method is nursed one's health for medicine and cosmetics beauty;Wherein, medicine conditioning predominantly uses Male sex hormone antagonist, antibiotic, tretinoin medicines etc. treat the disease, and curative effect determines, but toxic side effect is apparent, such as liver kidney function Energy damage, teratogenesis etc..Compared with medicine is nursed one's health, cosmetics beauty milder is also more popular with consumers.This work(to cosmetics Effect proposes higher requirement, and cosmetics used do not require nothing more than safe to use, and apparent thorn cannot be generated to site of administration Swash and damage, any resistance to the action of a drug can not be generated.
Based on this, it is particularly important to provide a kind of new cosmetics for being capable of effectively anti-acne.
The content of the invention
For in the prior art the defects of, the present invention is intended to provide a kind of Chinese medicine acne-eliminating cosmetic and preparation method thereof.This The Chinese medicine acne-eliminating cosmetic provided is provided, active skull cap components is selected to make raw material components, component compatibility science, safe and non-toxic secondary work With there is excellent acne-removing, take effect rapid and can effectively dispel acne print, can effectively meet all orders of society to skin care item It continuously promotes demand, realizes skin nursing from single maintenance type to skin disease prevention type, anti-aging health care type, strong The transformation of Kang Meili types.
For this purpose, the present invention provides following technical solution:
In a first aspect, the present invention provides the Chinese medical extract with acne-removing, Chinese medicine includes monkshood, radix ampelopsis, Chinese cassia tree, red One or more in Chinese herbaceous peony, Radix Angelicae Pubescentis, radix rehmanniae recen, radix aconiti agrestis, the bletilla striata, the root of Dahurain angelica, Rhizoma Et Radix Notopterygii, radix scrophulariae, elephant hide, Radix Angelicae Sinensis, kuh-seng and rheum officinale.
Preferably, the raw material components of Chinese medicine by weight, including:1~8 parts by weight of monkshood, 4~12 parts by weight of radix ampelopsis, 2~8 parts by weight of Chinese cassia tree, 5~10 parts by weight of the radix paeoniae rubrathe, 7~14 parts by weight of Radix Angelicae Pubescentis, 3~10 parts by weight of radix rehmanniae recen, 6~15 weight of radix aconiti agrestis Measure part, 5~10 parts by weight of the bletilla striata, 7~14 parts by weight of the root of Dahurain angelica, 1~8 parts by weight of Rhizoma Et Radix Notopterygii, 3~10 parts by weight of radix scrophulariae, elephant hide 7~15 Parts by weight, 3~10 parts by weight of 5~12 parts by weight of Radix Angelicae Sinensis, 5~12 parts by weight of kuh-seng and rheum officinale.
Second aspect, the present invention provides a kind of preparation method of the Chinese medical extract with acne-removing, including walking as follows Suddenly:S101:Radix Angelicae Sinensis with petroleum ether is extracted, filter afterwards and collects filtrate, obtains angelica extract;S102:By radix ampelopsis, meat It is decocted after osmanthus, the radix paeoniae rubrathe, Radix Angelicae Pubescentis and radix aconiti agrestis mixing with water, collects filtrate and concentrate;Enriched product is uniformly mixed with absolute ethyl alcohol, After take supernatant after stand at low temperature, recycling removes the ethyl alcohol in supernatant, obtains the first extracting solution;S103:By the root of Dahurain angelica, in vain Low temperature reflux extraction is carried out with ethyl alcohol after splendid achnatherum, monkshood and Rhizoma Et Radix Notopterygii mixing, collects extracting solution;Stand at low temperature after extracting solution is concentrated, Take supernatant;S104:With alcohol dipping after radix scrophulariae, kuh-seng and radix rehmanniae recen are mixed, collect supernatant;It will be cold after supernatant concentration Freeze, take supernatant;Diatomite stirring, filtering are added in afterwards, collect filtrate;S105:Talcum powder is heated, imports elephant hide afterwards, And in scald to heave and in coke yellow when take out;The talcum postcooling in resultant product is weeded out, is ground into fine powder afterwards;S106:It will Rheum officinale yellow rice wine spray is mixed thoroughly, is fried afterwards to color and luster and is deepened postcooling;S107:The product that S101~S106 is obtained mixes equal It is even, obtain Chinese medical extract.
Preferably, in S101:The addition of petroleum ether is 8 times of Radix Angelicae Sinensis quality, and Extracting temperature is 70 DEG C~80 DEG C, is carried It is 2~3 times to take number;In S102, the addition of water is 10 times of radix ampelopsis, Chinese cassia tree, the radix paeoniae rubrathe, Radix Angelicae Pubescentis and radix aconiti agrestis gross mass, is decocted Time is 1h~1.5h, and it is 2 times to decoct number, concentrates the filtrate to the 20% of original volume;By enriched product and isometric nothing Water-ethanol is uniformly mixed, and stands 48h with 10 DEG C~20 DEG C afterwards;In S103, it is 90% that ethyl alcohol, which specifically selects mass percentage concentration, Ethyl alcohol, reflux temperature be 30 DEG C~45 DEG C, return time 1h, reflow's cycle be 2~3 times;In S104, ethyl alcohol is specifically selected Mass percentage concentration is 95% ethyl alcohol, and dip time 7d, dipping time is 2 times, by supernatant concentration to original volume 10%, cooling time is for 24 hours.
The third aspect, application of the Chinese medical extract provided by the invention in product for resolving poxes and/or product additive is prepared.
Fourth aspect, the present invention provide a kind of Chinese medicine acne-eliminating cosmetic, raw material components by weight, including:Chinese medicine carries Take 12~20 parts by weight of object, 40~45 weight of 30~40 parts by weight of water, 4~6 parts by weight of the first mixture and the second mixture Part;Wherein, the raw material components of the first mixture include the one or more in propylene glycol, triethanolamine, preservative and antioxidant; The raw material components of second mixture include beeswax, octadecyl alcolol, sesame oil, lanolin, albolene, single stearic acid glycerine lipoprotein and liquid One or more in paraffin.
Preferably, the raw material components of Chinese medicine acne-eliminating cosmetic include:16 parts by weight of Chinese medical extract, 16 parts by weight of water, third 2 parts by weight of glycol, 1 parts by weight of triethanolamine, 1 parts by weight of preservative, 1 parts by weight of antioxidant, 5 parts by weight of beeswax, 1 weight of octadecyl alcolol Measure part, 1 parts by weight of sesame oil, 2 parts by weight of lanolin, 5 parts by weight of albolene, 5 parts by weight of single stearic acid glycerine lipoprotein and liquid stone 25 parts by weight of wax.
5th aspect, the present invention provide a kind of preparation method of Chinese medicine acne-eliminating cosmetic, comprise the following steps:S201:It will Water when being cooled to 70 DEG C~80 DEG C afterwards, adds in Chinese medical extract and the first mixture and stirs evenly in 100 DEG C of sterilizations; S202:Second mixture is heated to 70 DEG C~80 DEG C, adds in the product that S201 is obtained while stirring afterwards, continues stirring to temperature Degree obtains Chinese medicine acne-eliminating cosmetic less than 50 DEG C.
Above-mentioned technical proposal provided by the invention has the following advantages:
(1) Chinese medicine acne-eliminating cosmetic provided by the invention selects active skull cap components to make raw material components, component compatibility section It learns, safe without toxic side effect, there is excellent acne-removing, take effect rapid and can effectively dispel acne print, can effectively meet society Can each stratum skin care item are continuously promoted with demand, realize skin nursing from single maintenance type to skin disease prevention type, The transformation of anti-aging health care type, healthy and beautiful type.
(2) preparation method process stabilizing, the good product quality of Chinese medicine acne-eliminating cosmetic provided by the invention, in preparing Medicine acne-eliminating cosmetic can effectively achieve the purpose of anti-inflammatory and Sage Extract while safe without toxic side effect, and it is not It is only capable of effective anti-acne, moreover it is possible to the effectively growth of prevention dark sore acne.
(3) each raw material components selection of the invention is natural, and effect is excellent;Wherein, monkshood has dispelling wind and eliminating dampness, antalgic The effect of;Radix ampelopsis has the effect of clearing heat and detoxicating, eliminating stagnation to stop pain, myogenic sore;Chinese cassia tree have clearing heat and expelling damp, removing toxic substances, diuresis, dispersing blood stasis, The effect of quenching one's thirst;The radix paeoniae rubrathe has the effect of clearing heat and cooling blood, removing blood stasis and analgesics;Radix Angelicae Pubescentis has the effect of expelling wind and eliminating dampness, numbness relieving and pain relieving;Radix Rehmanniae Huang has the effect of clearing heat and cooling blood, fluid dryness;Radix aconiti agrestis searches wind prevailing over dampness, eliminating cold to stop pain, opens gas under phlegm, wet kidney and enhancing body, removing toxic substances treatment The effect of sore;The bletilla striata has the effect of tonifying lung, hemostasis, detumescence, myogenic, sore;The root of Dahurain angelica have wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving, The effect of brightening beauty;Rhizoma Et Radix Notopterygii has the effect of relieve heat cold-dampness, analgesic;Radix scrophulariae has clearing heat and cooling blood, Yin-nourishing and body fluid promoting, purging intense heat and detonicating, disappears The effect of swollen dissipating bind;Elephant hide has the effect of myogenic, sore, does not close up long for sore;Radix Angelicae Sinensis have warming meridian, promoting blood circulation and stopping pain it Effect, main function relieves pain, apocenosis myogenic, invigorating QI and blood;Kuh-seng has the effect of heat-clearing and damp-drying drug, desinsection, diuresis.For heat Dysentery is had blood in stool, jaundice renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, mange leprosy etc.;The active product of rheum officinale is led The effect of stagnant, removing pattogenic heat from the blood and toxic material from the body, promoting blood circulation;Sesame oil have profit under, removing toxic substances, desinsection, subside a swelling the effect of;Medical ventolin has very Good moisture-keeping efficacy;The skin care principle of vaseline is Water-In-Oil, there is very strong isolation water function, does not allow moisture evaporation.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description It obtains substantially or is recognized by the practice of the present invention.
Specific embodiment
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer Illustrate technical scheme, therefore be only used as example, and be not intended to limit the protection scope of the present invention and limit the scope of the invention.
Experimental method in following embodiments is conventional method unless otherwise specified.Examination used in following embodiments Material is tested, is to be commercially available from conventional reagent shop unless otherwise specified.Quantitative test in following embodiment, is all provided with Three repeated experiments are put, data are the average value or mean+SD of three repeated experiments.
Monkshood used, radix ampelopsis, Chinese cassia tree, the radix paeoniae rubrathe, Radix Angelicae Pubescentis, radix rehmanniae recen, radix aconiti agrestis, the bletilla striata, the root of Dahurain angelica, Qiang in following embodiments Work, radix scrophulariae, elephant hide, Radix Angelicae Sinensis, kuh-seng and rheum officinale meet related under each medicinal material item of text of Chinese Pharmacopoeia (version in 2016) Regulation.Before feeding intake, by identification, ingredients material object is consistent with title, and quality complies with standard.
The present invention provides a kind of Chinese medical extract with acne-removing, the raw material components of Chinese medicine by weight, including: 1~8 parts by weight of monkshood, 4~12 parts by weight of radix ampelopsis, 2~8 parts by weight of Chinese cassia tree, 5~10 parts by weight of the radix paeoniae rubrathe, 7~14 weight of Radix Angelicae Pubescentis Part, 3~10 parts by weight of radix rehmanniae recen, 6~15 parts by weight of radix aconiti agrestis, 5~10 parts by weight of the bletilla striata, 7~14 parts by weight of the root of Dahurain angelica, Rhizoma Et Radix Notopterygii 1~8 Parts by weight, 3~10 parts by weight of radix scrophulariae, 7~15 parts by weight of elephant hide, 5~12 parts by weight of Radix Angelicae Sinensis, 5~12 parts by weight of kuh-seng and rheum officinale 3 ~10 parts by weight.
In addition, for the above-mentioned Chinese medical extract with acne-removing, the present invention provides preparation methods:
S101:5~12 parts by weight of Chinese Angelica Root are taken, 70~80 DEG C of petroleum ethers for adding in 8 times of amounts extract 2~3 times, and merging carries Liquid is taken, petroleum ether is recycled under low temperature and obtains the oil of clear pale yellow color, there is Radix Angelicae Sinensis fragrance, it is spare.
S102:Take 6~12 parts by weight of radix ampelopsis, 4~8 parts by weight of Chinese cassia tree, 6~10 parts by weight of the radix paeoniae rubrathe, 8~12 weight of Radix Angelicae Pubescentis Part, 8~15 parts by weight of radix aconiti agrestis, the clear water for adding in 10 times of amounts decoct 1~1.5h;Its secondary decocting liquid is taken to merge, is stood overnight, mistake Filter, low temperature concentrate decocting liquid to the 20% of original volume, add in isometric absolute ethyl alcohol;The stand at low temperature 48h after being sufficiently stirred, Supernatant is taken, low temperature recycling ethyl alcohol obtains the first extracting solution.
S103:8~10 parts by weight of the root of Dahurain angelica, 6~10 parts by weight of the bletilla striata, 3~8 parts by weight of monkshood, 3~7 parts by weight of Rhizoma Et Radix Notopterygii, add 90% ethyl alcohol 500ml merges extracting solution in low temperature reflux 1h 2~3 times;Extracting solution is concentrated to the 10% of original volume, in- 10 DEG C stand for 24 hours, take supernatant.
S104:5~8 parts by weight of radix scrophulariae, 6~10 parts by weight of kuh-seng, 5~10 parts by weight of radix rehmanniae recen are taken, add in 95% ethyl alcohol 300 parts by weight are impregnated 7 days, take its supernatant;Then impregnated once with the ethyl alcohol of same amount again;Merge leachate in low temperature next time Ethyl alcohol is received to the 10% of original volume;Freezing takes supernatant for 24 hours, adds in diatomite stirring, filtering, takes filtrate spare.
S105:8~15 parts by weight of elephant hide are taken, cleans, is dried after being cut into long block;Talcum powder is put into pot and is heated, is imported Elephant hide scalds to being taken out when heaving and being in coke yellow, weeds out talcum, cool, be ground into fine powder.
S106:5~10 parts by weight yellow rice wine of rheum officinale spray is taken to mix thoroughly, it is slightly bored, it is cooled after being fried with warm fire to color and luster intensification standby With.
S107:The product that S101~S106 is obtained is uniformly mixed, and obtains Chinese medical extract.
In addition, by the Chinese medical extract of the present invention in Chinese medicine acne-eliminating cosmetic, the raw material components of cosmetics to be by weight Part meter, including:12~20 parts by weight of Chinese medical extract, 30~40 parts by weight of water, 4~6 parts by weight of the first mixture and second 40~45 parts by weight of mixture;Wherein, the raw material components of the first mixture include propylene glycol, triethanolamine, preservative and antioxygen One or more in agent;The raw material components of second mixture include beeswax, octadecyl alcolol, sesame oil, lanolin, albolene, list One or more in glyceryl stearate and atoleine.
The preparation method of cosmetics includes:S201:By water in 100 DEG C of sterilizations, when being cooled to 70 DEG C~80 DEG C afterwards, add in Chinese medical extract and the first mixture simultaneously stir evenly.S202:Second mixture is heated to 70 DEG C~80 DEG C, back stirring Side adds in the product that S201 is obtained, and continues stirring to temperature less than 50 DEG C, obtains Chinese medicine acne-eliminating cosmetic.
It illustrates With reference to embodiment:
Embodiment one
The present invention provides a kind of Chinese medicine acne-eliminating cosmetic, and preparation method includes:
(1) Chinese medicine extract is prepared
S101:12 parts by weight of Chinese Angelica Root are taken, 70 DEG C of petroleum ethers for adding in 8 times of amounts extract 3 times, merge extracting solution, in low The lower recycling petroleum ether of temperature obtains the oil of clear pale yellow color, there is Radix Angelicae Sinensis fragrance, spare.S102:Take 6 parts by weight of radix ampelopsis, 8 weight of Chinese cassia tree Part, 6 parts by weight of the radix paeoniae rubrathe, 12 parts by weight of Radix Angelicae Pubescentis, 8 parts by weight of radix aconiti agrestis, the clear water for adding in 10 times of amounts decoct 1.5h;Take its secondary decocting liquid Merge, stand overnight, filter, low temperature concentrates decocting liquid to the 20% of original volume, adds in isometric absolute ethyl alcohol;Through fully stirring Rear stand at low temperature 48h is mixed, takes supernatant, low temperature recycling ethyl alcohol obtains the first extracting solution.S103:10 parts by weight of the root of Dahurain angelica, the bletilla striata 6 Parts by weight, 8 parts by weight of monkshood, 3 parts by weight of Rhizoma Et Radix Notopterygii add 90% ethyl alcohol 500ml to merge extracting solution in low temperature reflux 1h 3 times; Extracting solution is concentrated to the 10% of original volume, is stood for 24 hours in -10 DEG C, takes supernatant.S104:Take 5 parts by weight of radix scrophulariae, kuh-seng 10 Parts by weight, 5 parts by weight of radix rehmanniae recen add in 95% ethyl alcohol, 300 parts by weight and impregnate 7 days, take its supernatant;Then again with same amount Ethyl alcohol impregnates once;Merge leachate and ethyl alcohol is recycled under low temperature to the 10% of original volume;Freezing takes supernatant for 24 hours, adds in silicon Diatomaceous earth stirring, filtering, take filtrate spare.S105:15 parts by weight of elephant hide are taken, cleans, is dried after being cut into long block;Talcum powder is put into Heating in pot, imports elephant hide, scalds to being taken out when heaving and being in coke yellow, weeds out talcum, cool, be ground into fine powder.S106:Take rheum officinale 5 parts by weight yellow rice wine spray is mixed thoroughly, slightly bored, is cooled after being fried with warm fire to color and luster intensification spare.S107:S101~S106 is obtained Product be uniformly mixed, obtain Chinese medical extract.
(2) acne-eliminating cosmetic is prepared
S201:By water in 100 DEG C of sterilizations, when being cooled to 75 DEG C afterwards, add in Chinese medical extract and the first mixture and stir It mixes uniformly.S202:Second mixture is heated to 75 DEG C, adds in the product that S201 is obtained while stirring afterwards, continues stirring extremely Temperature is less than 50 DEG C, obtains Chinese medicine acne-eliminating cosmetic.Wherein, the raw material components of the first mixture include 2 parts by weight of propylene glycol, three 1 parts by weight of 1 parts by weight of ethanolamine, 1 parts by weight of preservative and antioxidant;The raw material components of second mixture include 5 weight of beeswax Measure part, 1 parts by weight of octadecyl alcolol, 1 parts by weight of sesame oil, 2 parts by weight of lanolin, 5 parts by weight of albolene, single stearic acid glycerine lipoprotein 5 25 parts by weight of parts by weight and atoleine.
Embodiment two
The present invention provides a kind of Chinese medicine acne-eliminating cosmetic, and preparation method includes:
(1) Chinese medicine extract is prepared
S101:5 parts by weight of Chinese Angelica Root are taken, 80 DEG C of petroleum ethers for adding in 8 times of amounts extract 2 times, merge extracting solution, in low temperature Lower recycling petroleum ether obtains the oil of clear pale yellow color, there is Radix Angelicae Sinensis fragrance, spare.S102:Take 12 parts by weight of radix ampelopsis, 4 weight of Chinese cassia tree Part, 10 parts by weight of the radix paeoniae rubrathe, 8 parts by weight of Radix Angelicae Pubescentis, 15 parts by weight of radix aconiti agrestis, the clear water for adding in 10 times of amounts decoct 1h;Take its secondary decocting liquid Merge, stand overnight, filter, low temperature concentrates decocting liquid to the 20% of original volume, adds in isometric absolute ethyl alcohol;Through fully stirring Rear stand at low temperature 48h is mixed, takes supernatant, low temperature recycling ethyl alcohol obtains the first extracting solution.S103:8 parts by weight of the root of Dahurain angelica, the bletilla striata 10 Parts by weight, 3 parts by weight of monkshood, 7 parts by weight of Rhizoma Et Radix Notopterygii add 90% ethyl alcohol 500ml to merge extracting solution in low temperature reflux 1h 2 times; Extracting solution is concentrated to the 10% of original volume, is stood for 24 hours in -10 DEG C, takes supernatant.S104:Take 8 parts by weight of radix scrophulariae, 6 weight of kuh-seng Part, 10 parts by weight of radix rehmanniae recen are measured, 95% ethyl alcohol, 300 parts by weight is added in and impregnates 7 days, take its supernatant;Then again with same amount Ethyl alcohol impregnates once;Merge leachate and ethyl alcohol is recycled under low temperature to the 10% of original volume;Freezing takes supernatant for 24 hours, adds in silicon Diatomaceous earth stirring, filtering, take filtrate spare.S105:8 parts by weight of elephant hide are taken, cleans, is dried after being cut into long block;Talcum powder is put into Heating in pot, imports elephant hide, scalds to being taken out when heaving and being in coke yellow, weeds out talcum, cool, be ground into fine powder.S106:Take rheum officinale 10 parts by weight yellow rice wine spray is mixed thoroughly, slightly bored, is cooled after being fried with warm fire to color and luster intensification spare.S107:S101~S106 is obtained To product be uniformly mixed, obtain Chinese medical extract.
(2) acne-eliminating cosmetic is prepared
S201:By water in 100 DEG C of sterilizations, when being cooled to 75 DEG C afterwards, add in Chinese medical extract and the first mixture and stir It mixes uniformly.S202:Second mixture is heated to 75 DEG C, adds in the product that S201 is obtained while stirring afterwards, continues stirring extremely Temperature is less than 50 DEG C, obtains Chinese medicine acne-eliminating cosmetic.Wherein, the raw material components of the first mixture include 2 parts by weight of propylene glycol, three 1 parts by weight of 1 parts by weight of ethanolamine, 1 parts by weight of preservative and antioxidant;The raw material components of second mixture include 5 weight of beeswax Measure part, 1 parts by weight of octadecyl alcolol, 1 parts by weight of sesame oil, 2 parts by weight of lanolin, 5 parts by weight of albolene, single stearic acid glycerine lipoprotein 5 25 parts by weight of parts by weight and atoleine.
The cosmetics that the embodiment of the present invention one and embodiment two are obtained, by function assessment experiment come its anti-acne of system evaluation Effect:
First, toxicity test
The small white mouse 20 (each 10 of male and female) that weight is selected to be 18~22g takes the cosmetics 10g of the present invention, adds deionization Concentrate 20ml is made in water, and every small white mouse gives concentrate 0.3ml gavages, twice daily;Observation 15 days, small white mouse is healthy Existence, it is without any side effects;Blood picture, liver function, each organs and tissues state, the indifference compared with normal small white mouse is dissected and observed It is different.It is demonstrated experimentally that cosmetics provided by the invention are nontoxic.
2nd, human trial
Detailed directions are:After cleaning skin, the Chinese medicine acne-eliminating cosmetic of 0.1~0.3g is taken to be applied to volunteer's face, and it is light Forlement 5s~10s.
300 whelk, acne and sore skin volunteer volunteers are collected, wherein, 150 people of women, 50 people of male, maximum 35 years old age, minimal ages 16 years old.Above-mentioned volunteer is divided into three groups, the first two groups changes for trying out various embodiments of the present invention respectively Cosmetic, the 3rd group is tried out commercially available acne-eliminating cosmetic, after 10 days, observes result.Whelk, acne and sore skin are shown as:Face Portion's redness, acne and sore or acne print.
Wherein, observation of curative effect standard is:It cures:After treatment, original acne or dark sore fully absorb, because acne is reacted And the pigmentation point left absorbs completely or partially, skin is smooth, there is no the appearance of newborn acne bleb, through follow-up 5 months Interior no recidivist is healing.It is effective:After several treatments, original acne papule starts to soften, absorb, dark sore detumescence, skin by It is gradually flat, bleach, newborn acne count greatly reduces or there is no the appearance of newborn dark sore.It is invalid:After treatment 30 days, original acne Papule has no that absorption or absorption are poor, and detumescence is slow, and has newborn acne, dark sore to occur simultaneously.Specific test situation such as 1 institute of table Show.
1 human trial concrete condition list of table
Experiment finds that Chinese medicine acne-eliminating cosmetic provided by the invention has good anti-acne, repairs acne print, prevents and dispels The effect of acne and sore, high efficiency is up to 100%, and safe without toxic side effect.
Certainly, except the situation that embodiment one and embodiment two are enumerated, prepared by the weight percent of other raw material components Other parameter in journey is also possible.
Chinese medicine acne-eliminating cosmetic provided by the invention selects active skull cap components to make raw material components, component compatibility science, peace Completely without toxic side effect, there is excellent acne-removing, take effect rapid and can effectively dispel acne print, can effectively meet each rank of society Layer continuously promotes skin care item demand, realize skin nursing from single maintenance type to skin disease prevention type, delay to decline The transformation of old health, healthy and beautiful type.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or the spy for combining the embodiment or example description Point is contained at least one embodiment of the present invention or example.In the present specification, schematic expression of the above terms is not It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office It is combined in an appropriate manner in one or more embodiments or example.In addition, without conflicting with each other, the skill of this field Art personnel can tie the different embodiments described in this specification or example and different embodiments or exemplary feature It closes and combines.
Although the embodiment of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is impossible to limitation of the present invention is interpreted as, those of ordinary skill in the art within the scope of the invention can be to above-mentioned Embodiment is changed, changes, replacing and modification.

Claims (8)

1. a kind of Chinese medical extract with acne-removing, it is characterised in that:
The Chinese medicine include monkshood, radix ampelopsis, Chinese cassia tree, the radix paeoniae rubrathe, Radix Angelicae Pubescentis, radix rehmanniae recen, radix aconiti agrestis, the bletilla striata, the root of Dahurain angelica, Rhizoma Et Radix Notopterygii, radix scrophulariae, as One or more in skin, Radix Angelicae Sinensis, kuh-seng and rheum officinale.
2. the Chinese medical extract according to claim 1 with acne-removing, which is characterized in that the raw material group of the Chinese medicine Point by weight, including:
1~8 parts by weight of monkshood, 4~12 parts by weight of radix ampelopsis, 2~8 parts by weight of Chinese cassia tree, 5~10 parts by weight of the radix paeoniae rubrathe, 7~14 weight of Radix Angelicae Pubescentis Measure part, 3~10 parts by weight of radix rehmanniae recen, 6~15 parts by weight of radix aconiti agrestis, 5~10 parts by weight of the bletilla striata, 7~14 parts by weight of the root of Dahurain angelica, Rhizoma Et Radix Notopterygii 1 ~8 parts by weight, 3~10 parts by weight of radix scrophulariae, 7~15 parts by weight of elephant hide, 5~12 parts by weight of Radix Angelicae Sinensis, 5~12 parts by weight of kuh-seng and big Yellow 3~10 parts by weight.
3. the preparation method of the Chinese medical extract with acne-removing described in claim 1 or 2, which is characterized in that including such as Lower step:
S101:Radix Angelicae Sinensis with petroleum ether is extracted, filter afterwards and collects filtrate, obtains angelica extract;
S102:It is decocted, collect filtrate and concentrated with water after radix ampelopsis, Chinese cassia tree, the radix paeoniae rubrathe, Radix Angelicae Pubescentis and radix aconiti agrestis are mixed;By enriched product Be uniformly mixed with absolute ethyl alcohol, after take supernatant after stand at low temperature, recycling removes the ethyl alcohol in supernatant, obtains first and carries Take liquid;
S103:Low temperature reflux extraction is carried out with ethyl alcohol after the root of Dahurain angelica, the bletilla striata, monkshood and Rhizoma Et Radix Notopterygii are mixed, collects extracting solution;It will extraction Stand at low temperature after liquid concentration, takes supernatant;
S104:With alcohol dipping after radix scrophulariae, kuh-seng and radix rehmanniae recen are mixed, collect supernatant;It will freeze, take after supernatant concentration Supernatant;Diatomite stirring, filtering are added in afterwards, collect filtrate;
S105:Talcum powder is heated, imports elephant hide afterwards, and in scalding to heaving and in coke yellow when takes out;Weed out resultant product In talcum postcooling, be ground into fine powder afterwards;
S106:Rheum officinale yellow rice wine spray is mixed thoroughly, is fried afterwards to color and luster and deepens postcooling;
S107:The obtained products of the S101~S106 are uniformly mixed, obtain the Chinese medical extract.
4. the preparation method of the Chinese medical extract according to claim 3 with acne-removing, it is characterised in that:
In the S101:The addition of petroleum ether is 8 times of the Radix Angelicae Sinensis quality, and Extracting temperature is 70 DEG C~80 DEG C, extraction Number is 2~3 times;
In the S102, the addition of water is 10 times of the radix ampelopsis, Chinese cassia tree, the radix paeoniae rubrathe, Radix Angelicae Pubescentis and radix aconiti agrestis gross mass, decocting time For 1h~1.5h, it is 2 times to decoct number, concentrates the filtrate to the 20% of original volume;By enriched product and isometric anhydrous second Alcohol is uniformly mixed, and stands 48h with 10 DEG C~20 DEG C afterwards;
In the S103, ethyl alcohol specifically selects the ethyl alcohol that mass percentage concentration is 90%, and reflux temperature is 30 DEG C~45 DEG C, reflux Time is 1h, and reflow's cycle is 2~3 times;
In the S104, ethyl alcohol specifically selects the ethyl alcohol that mass percentage concentration is 95%, dip time 7d, dipping time 2 Secondary, by the 10% of supernatant concentration to original volume, cooling time is for 24 hours.
5. application of the Chinese medical extract in product for resolving poxes and/or product additive is prepared described in claim 1 or 2.
6. a kind of Chinese medicine acne-eliminating cosmetic, which is characterized in that raw material components by weight, including:
12~20 parts by weight of Chinese medical extract, 30~40 parts by weight of water, 4~6 parts by weight of the first mixture and the second mixture 40~45 parts by weight;
Wherein, the raw material components of first mixture include propylene glycol, triethanolamine, preservative and antioxidant in one kind or It is a variety of;It is sweet that the raw material components of second mixture include beeswax, octadecyl alcolol, sesame oil, lanolin, albolene, monostearate One or more in grease and atoleine.
7. Chinese medicine acne-eliminating cosmetic according to claim 6, which is characterized in that including:
16 parts by weight of Chinese medical extract, 16 parts by weight of water, 2 parts by weight of propylene glycol, 1 parts by weight of triethanolamine, 1 weight of preservative Part, 1 parts by weight of antioxidant, 5 parts by weight of beeswax, 1 parts by weight of octadecyl alcolol, 1 parts by weight of sesame oil, 2 parts by weight of lanolin, albolene 25 parts by weight of 5 parts by weight, 5 parts by weight of single stearic acid glycerine lipoprotein and atoleine.
8. the preparation method of the Chinese medicine acne-eliminating cosmetic described in claim 6 or 7, which is characterized in that comprise the following steps:
S201:By water in 100 DEG C of sterilizations, when being cooled to 70 DEG C~80 DEG C afterwards, Chinese medical extract and the first mixture are added in simultaneously It stirs evenly;
S202:Second mixture is heated to 70 DEG C~80 DEG C, adds in the product that the S201 is obtained while stirring afterwards, is continued Stirring, less than 50 DEG C, obtains the Chinese medicine acne-eliminating cosmetic to temperature.
CN201711443721.XA 2017-12-27 2017-12-27 Chinese medicine acne-eliminating cosmetic and preparation method thereof Pending CN108042427A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113057931A (en) * 2021-04-16 2021-07-02 雅威盛(北京)科技发展有限公司 Plant composition for preparing acne-removing preparation, acne-removing preparation and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113057931A (en) * 2021-04-16 2021-07-02 雅威盛(北京)科技发展有限公司 Plant composition for preparing acne-removing preparation, acne-removing preparation and preparation method thereof

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Application publication date: 20180518