CN108001744B - Automatic collecting, crushing and packaging system and method for dextran biomacromolecule finished products - Google Patents

Automatic collecting, crushing and packaging system and method for dextran biomacromolecule finished products Download PDF

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Publication number
CN108001744B
CN108001744B CN201711395355.5A CN201711395355A CN108001744B CN 108001744 B CN108001744 B CN 108001744B CN 201711395355 A CN201711395355 A CN 201711395355A CN 108001744 B CN108001744 B CN 108001744B
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pipeline
vacuum
valve
bin
filter
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CN108001744A (en
Inventor
王京光
魏哲
王长海
孙兆永
王琰
李晓芸
郑睿智
孙恒
徐凯
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Shandong Jinyang Pharmaceutical Co Ltd
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Shandong Jinyang Pharmaceutical Co Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B37/00Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
    • B65B37/14Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged by pneumatic feeders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C21/00Disintegrating plant with or without drying of the material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/08Separating or sorting of material, associated with crushing or disintegrating
    • B02C23/14Separating or sorting of material, associated with crushing or disintegrating with more than one separator
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/18Adding fluid, other than for crushing or disintegrating by fluid energy
    • B02C23/20Adding fluid, other than for crushing or disintegrating by fluid energy after crushing or disintegrating
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00Automatic control, checking, warning, or safety devices

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  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Disintegrating Or Milling (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

The invention belongs to the field of dextran biological macromolecule production, and in particular relates to an automatic dextran biological macromolecule finished product collecting, crushing and packaging system and method. The automatic collecting, crushing and packaging system can realize the automatic drying of products until the packaging is free from external contact, the product quality is improved, the cleanliness detection index reaches more than 99.5%, the automatic operation efficiency is high, the labor capacity of staff is reduced, no dust is generated in the process, the yield is improved by 0.2-0.3%, the occupational hazard is reduced, the control system is more stable through the use of the balance valve, the regulating valve and the pneumatic valve, the staff work is mainly inspection, the staff allocation is reduced by 3-5 persons, the production cost is reduced, the online cleaning and the use of a sterile filter are realized, the service life of equipment is prolonged, and the yield is improved by 0.1-0.3%; and detecting 100% of finished product microorganism limit.

Description

Automatic collecting, crushing and packaging system and method for dextran biomacromolecule finished products
Technical Field
The invention belongs to the field of biological macromolecule production, and particularly relates to an automatic collecting, crushing and packaging system and method for a dextran biological macromolecule finished product.
Background
In the process of producing dextran biomacromolecules, an aggregate packaging device is required to collect, convey and package materials. During the production process, we find that the following problems exist in the drying and packaging process of the dextran biomacromolecule: ① The discharging port of the general dryer is connected with a bag or a skip car, dust is generated, and secondary pollution exists; ② The materials which are taken out can be crushed after being fed, and the problems of dust generation and labor intensity exist; ③ The biological macromolecules have the characteristics of high viscosity and high moisture absorption, the materials are high in temperature or high in air humidity in the environment and absorb moisture when being crushed, the materials are easy to form glue cakes and are extremely strong in adhesiveness, so that the crushing speed of a crusher is low, the yield loss is high (2-3% of normal general loss), meanwhile, the hardness of the glue cakes is high after the glue cakes are solidified, and the crusher equipment is extremely easy to damage; ④ The original process environment has high clean degree requirement and large occupied area, and the whole set of device comprises drying equipment, crushing and mixing equipment and packaging equipment which all need to be built with clean areas to ensure the product quality (especially the microbial limit); ⑤ Dust generated in the packaging process gathers, moisture in air is absorbed rapidly to become a glue cake shape on equipment and facilities, and cleaning is difficult; ⑥ The cleaning of equipment is difficult, the cleaning of equipment and pipeline inside should product characteristic clearance be difficult.
Disclosure of Invention
In order to solve the problems, the invention provides an automatic collecting, crushing and packaging system for a dextran biomacromolecule finished product, which has the following specific technical scheme:
The utility model provides a dextran biological macromolecule finished product automatic collection smashes package system, includes the desiccator, the discharge gate of desiccator is connected with the feed inlet of rubbing crusher, the discharge gate of rubbing crusher passes through the pipeline and is connected with the feed inlet of feed bin, the discharge gate of feed bin passes through vacuum material loading pipeline and is connected with the feed inlet of filter, the discharge gate of filter passes through the pipeline and closes the fan to be connected, it is connected with the feed inlet of crystal temporary storage jar to close the fan, the discharge gate of crystal temporary storage jar passes through the pipeline and is connected with low temperature screw crusher's feed inlet, low temperature screw crusher's discharge gate passes through vacuum material loading pipeline and is connected with cyclone's feed inlet, cyclone's discharge gate passes through the pipeline and closes the fan to be connected, it is connected with mixing tank's feed inlet to close the fan, the discharge gate of mixing tank passes through the pipeline and is connected with the feed inlet of feed bin, it passes through vacuum material loading pipeline and cyclone's feed inlet to go up the feed inlet, cyclone's discharge gate passes through the pipeline and is connected with metal detector, the discharge gate passes through the pipeline and is connected with the fan, the metal detector is connected with the feed bin.
Preferably, two bins and a filter are arranged, the two bins are used for one time, the filter is a 0.22 micron sterile titanium rod filter, the pulverizer is a pendulum coarse pulverizer, the pendulum coarse pulverizer can realize the interchangeable feeding of the two bins, the pulverizer is provided with a quick-open type observation maintenance hole, the running condition is observed at any time, and if the abnormality exists, the treatment can be opened; be provided with pneumatic butterfly valve on the pipeline between the feed inlet of rubbing crusher and feed bin, be provided with pneumatic ball valve on the pipeline of the discharge gate department of feed bin, be provided with the washing discharge port on the vacuum material loading pipeline between feed bin and the filter, be provided with jar, sight glass lamp and quick-open type observation hole on the feed bin, jar setting is in 1/3 department of feed bin, can prevent to smash the back granule and stop up, and sight glass lamp and quick-open type observation hole are convenient for observe and the quick-operation abnormal condition, the bottom of feed bin is provided with the wheel of taking the brake block, and when needs whole change reserve feed bin, the dismantlement pushes away direct mount reserve feed bin just can not influence the progress.
Preferably, the vacuum port at the upper end of the storage bin is connected with the vacuum system through a pipeline, the vacuum system comprises a vacuum unit, the vacuum unit is respectively connected with two groups of 0.01-micrometer sterile filters through pipelines, the sterile filters are respectively connected with the vacuum port at the upper end of the storage bin through pipelines, ball valves are respectively arranged on the pipelines at the air inlet and the air outlet of the sterile filters, a pneumatic air valve is arranged on the pipeline at the vacuum port at the upper end of the storage bin, vacuum opening is realized, a vacuum detector and a balance valve are arranged on the pipeline between the sterile filters and the storage bin, and the vacuum detector can keep vacuum degree detection and the balance valve to control the whole system to be stable.
Preferably, the gas port at the upper end of the storage bin is connected with the Roots blower system through a pipeline, the Roots blower system comprises a Roots blower set, the Roots blower set is respectively connected with two groups of 0.01-micrometer sterile filters through pipelines, the sterile filters are respectively connected with the gas port at the upper end of the storage bin through pipelines, ball valves are arranged on the pipelines at the gas inlet and the gas outlet of the sterile filters, a wind distributing valve is arranged on the pipeline at the gas port at the upper end of the storage bin to realize the opening of wind, a wind volume detector and a balance valve are arranged on the pipeline between the sterile filters and the storage bin, and the wind volume detector keeps the wind volume to stably run and the balance valve controls the whole system to be stable. The material conveying is realized through the opening exchange of the vacuum pneumatic valve and the air distribution valve; and stable operation is realized through vacuum and wind detection and balance.
Preferably, a vacuum port at the upper end of the filter is connected with a vacuum unit through a pipeline, a balance valve and a vacuum detector are arranged on the pipeline between the vacuum port and the vacuum unit, a pneumatic valve is arranged at the vacuum port at the upper end of the filter, and when the pressure of a vacuum feeding pipeline is more than 5 Pa through a vacuum detection probe, the filter is judged to be blocked and needs to be cleaned; and a wind port at the upper end of the filter is connected with an instrument wind source distribution device through a pipeline, the back blowing control interval time is set to be 100-600 seconds, and the back blowing operation is carried out on the titanium rod filter. The instrument air source distribution device is respectively provided with an instrument air pipeline with the diameter of 4-12mm, a pneumatic valve air pipeline, a balance valve air pipeline and a counter-blowing pipeline with the diameter of 20-38, so that the pneumatic valve, the balance valve and the blowing valve can be opened.
As the preference, all be provided with sight hole lamp, cover, agitating unit and heat preservation jacket on crystal temporary storage tank and the blending tank, the superheated water business turn over pipeline is established to jar body below, and the water is lower than intaking 5-10cm, and the drain valve is established to the water place, be provided with the observation hole on the cover, crystal temporary storage tank and the discharge gate department of blending tank all are provided with electric control valve, control discharge rate, advance the pulverizer volume control, electric control valve links to each other with low temperature screw pulverizer through the flexible coupling, is provided with the air inlet filter on pulverizer fixed blade disc, the movable blade disc on the low temperature screw pulverizer respectively, install 0.45mm prefilter and 0.01mm aseptic smart filter in the air inlet filter.
Preferably, the upper part of the cyclone separator is connected with an induced draft fan through a pipeline, and the induced draft fan is connected with a water curtain dust removal system through a pipeline to realize tail gas treatment; the feeding pipeline in the feeding bin enters the feeding bin for 3-5cm, and the discharging pipe in the feeding bin is 3-5cm away from the bottom.
As the preference, dextran biomacromolecule finished product automatic collection smashes package system still is provided with cleaning system, and cleaning system can realize online cleaning, cleaning system includes overheated water system and pure water system, overheated water system and pure water system's delivery port are connected with the water inlet on feed bin, crystal temporary storage tank, blending tank, the filter respectively through the pipeline, all be provided with the ball valve on the pipeline of overheated water system and pure water system's delivery port department, feed bin, crystal temporary storage tank, blending tank, the water inlet department on the filter all is provided with pneumatic valve, all be provided with the shower in feed bin, crystal temporary storage tank, the blending tank, the filter, be provided with the shower on the shower, the shower is connected with the water inlet, the shower in feed bin and the filter is fan-shaped 60 degrees shower, the shower in crystal temporary storage tank and the blending tank is 360 degrees rotatory shower, establishes the exhaust valve before the electric control valve of crystal temporary storage tank and blending tank below, and the exhaust valve is established on the pipeline that low temperature spiral grinder and vibration screen separator and cyclone separator are connected. The cleaning is to clean with hot water and then clean with purified water.
Preferably, the intelligent air conditioner further comprises a control system, the control system comprises a controller data communication system, the pneumatic valve, the electric regulating valve, the balance valve, the vacuum detector and the air volume detector are electrically connected with the controller data communication system, the controller data communication system comprises a detector transmitter, the pneumatic valve, the electric regulating valve and a balance valve actuator, the controller data communication system is connected with an operation microcomputer, the control system can realize field control, and further can realize computer online remote control.
The invention also discloses a method for automatically collecting, crushing and packaging the dextran biomacromolecule finished product, which adopts the following technical scheme:
A method for automatically collecting, crushing and packaging a dextran biomacromolecule finished product is characterized in that: completed by the automatic collection and crushing packaging system according to any one of claims 1 to 9, comprising the following steps:
(1) The dextran biological macromolecule 1000 crystal enters a dryer to be dried until the viscosity is 5-10 ten thousand centipoise, enters a pendulum type coarse crusher to be coarsely crushed, the particle size of the coarsely crushed particles is 3-4 mm, and the coarsely crushed particles enter a 0.22 micrometer sterile titanium rod filter through a vacuum feeding pipeline to be filtered. Setting the interval time of back blowing control to be 100-600 seconds, and carrying out back blowing operation on a 0.22-micrometer sterile titanium rod filter through an instrument air source distribution device, wherein in the feeding process, materials contact with the outer layer of the filter, dust is attached to the surface of the filter for a long time, the feeding speed is reduced, and the back blowing ensures the normal feeding of the materials and the service life of the filter; the only contact with the outside in the material conveying and mixing process is air, and the use of all levels of filters in the system ensures that the air contacted with the material is in a sterile state, thereby achieving the improvement and stability of the quality of the finished product, and particularly achieving the microbial limit.
(2) The particles enter a crystal temporary storage tank through a shut-down fan to be stirred, then enter a low-temperature spiral crusher to be finely crushed with 120-300 meshes, enter a mixing tank to be stirred and mixed after being separated by a cyclone separator, and then are sieved by a vibration sieving machine to obtain a finished product;
(3) After entering the feeding bin, the finished product enters the packaging bin after being separated by the cyclone separator through the feeding pipe, and then enters the metal detector and the automatic packaging machine respectively under the action of the fan to finish packaging.
The beneficial effects of the invention are that
1. The product has no external contact from drying to packaging, the product quality is improved, and the cleanliness detection index reaches more than 99.5%.
2. High efficiency, reduced labor capacity of staff, no dust generation in the process, 0.2-0.3% of yield improvement and occupation hazard reduction.
3. Through the use of the balance valve, the regulating valve and the pneumatic valve, the control system is more stable, the work of staff is mainly patrol, the configuration of the staff is reduced by 3-5 persons, and the production cost is reduced.
4. The use of online cleaning and sterile filters improves the service life of equipment and the yield by 0.1-0.3%; and detecting 100% of finished product microorganism limit.
5. The invention only needs to set up the clean area at the packaging port, other devices are arranged in the general production area, the clean area is greatly reduced, the general production area is enlarged, and the production management and safety management levels are reduced; the fixed investment is saved, and the enterprise management is more convenient.
6. The cleaning system uses 85-DEG C hot water or steam to clean the inside of equipment and pipelines, the product is dissolved, the cleaning effect is good, and after the hot water is cleaned, the cleaning system uses purified water to clean the equipment and the pipelines, so that the cleaning degree of the cleaning system can be further ensured.
Drawings
Fig. 1 is a schematic structural diagram of embodiment 1.
In the figure: 1: a dryer; 2: a pulverizer; 3: a storage bin; 4: a filter; 5: turning off the fan; 6: a crystal temporary storage tank; 7: a low-temperature screw pulverizer; 8: a cyclone separator; 9: a mixing tank; 10: vibrating the screening machine; 11: feeding a bin; 12: an evacuation valve; 13: packaging bin; 14: a metal detector; 15: an automatic packaging machine; 16: quick-opening observation and maintenance hole; 17: a jar; 18: a vision aperture lamp; 19: a wheel; 20: a vacuum unit; 21: a sterile filter; 22: a vacuum detector; 23: a balancing valve; 24: cleaning a discharge port; 25: roots blower group; 26: an air quantity detector; 27: a shower pipe; 28: a spray header; 29: a superheated water system; 30: a pure water system; 31: an instrument air source distribution device; 32: an air inlet filter; 33: an induced draft fan; 34: a water curtain dust removal system.
Detailed Description
The invention is further described below in connection with specific embodiments.
Example 1
The utility model provides a dextran biological macromolecule finished product automatic collection smashes package system, includes desiccator 1, desiccator 1's discharge gate and pulverizer 2's feed inlet intercommunication, pulverizer 2's discharge gate passes through the pipeline and is connected with pulverizer 3's feed inlet, pulverizer 3's discharge gate passes through the vacuum feed pipe and is connected with filter 4's feed inlet, filter 4's discharge gate passes through the pipeline and closes fan 5 to be connected, it is connected with crystal temporary storage tank 6's feed inlet to close fan 5, crystal temporary storage tank 6's discharge gate passes through the pipeline and is connected with pulverizer 7's feed inlet, pulverizer 7's discharge gate passes through the vacuum feed pipe and is connected with pulverizer 8's feed inlet, pulverizer 8's discharge gate passes through the pipeline and is connected with the fan that closes, it is connected with mixer 9's feed inlet to close the fan, mixer 9's discharge gate passes through the pipeline and is connected with vibratory separator 10's feed inlet, vibratory separator 10's discharge gate passes through the pipeline and closes fan 5 to be connected with material loading bin 11's feed inlet, it is connected with pulverizer's 13 through the pipeline and is connected with pulverizer's feed inlet that the cyclone separator's 13, the material outlet passes through the pipeline and is connected with pulverizer's 13 to the cyclone separator's feed inlet, the detector's 13 is connected with pulverizer's feed inlet and is connected with pulverizer's feed inlet.
Preferably, two storage bins 3 and 4 are respectively provided, the filter 4 is a 0.22 micron sterile titanium rod filter, the pulverizer 2 is a pendulum coarse pulverizer, a quick-opening type observation maintenance hole 16 is formed in the pulverizer, a pneumatic butterfly valve is arranged on a pipeline between the pulverizer 2 and a feed inlet of the storage bins 3, a pneumatic ball valve is arranged on a pipeline at a discharge hole of the storage bins 3, a cleaning discharge hole 24 is formed in a vacuum feeding pipeline between the storage bins 3 and the filter 4, a jar 17, a sight hole lamp 18 and the quick-opening type observation maintenance hole 16 are formed in the storage bins 3, and wheels 19 with brake pads are arranged at the bottoms of the storage bins 3.
Preferably, the vacuum port at the upper end of the storage bin 3 is connected with a vacuum system through a pipeline, the vacuum system comprises a vacuum unit 20, the vacuum unit 20 is respectively connected with two groups of 0.01-micrometer sterile filters 21 through pipelines, the sterile filters 21 are respectively connected with the vacuum port at the upper end of the storage bin 3 through pipelines, ball valves are respectively arranged on the pipelines at the air inlet and the air outlet of the sterile filters 21, a pneumatic valve is arranged on the pipeline at the vacuum port at the upper end of the storage bin 3, and a vacuum detector 22 and a balance valve 23 are arranged on the pipeline between the sterile filters 21 and the storage bin 3.
Preferably, the gas port at the upper end of the storage bin 3 is connected with the Roots blower system through a pipeline, the Roots blower system comprises a Roots blower set 25, the Roots blower set 25 is respectively connected with two groups of 0.01-micrometer sterile filters through pipelines, the sterile filters are respectively connected with the gas port at the upper end of the storage bin 3 through pipelines, ball valves are arranged on the pipelines at the gas inlet and the gas outlet of the sterile filters, a wind distribution valve is arranged on the pipeline at the gas port at the upper end of the storage bin 3, and a wind volume detector 26 and a balance valve are arranged on the pipeline between the sterile filters and the storage bin 3.
Preferably, the vacuum port at the upper end of the filter 4 is connected with the vacuum unit 20 through a pipeline, a balance valve and a vacuum detector are arranged on the pipeline between the vacuum port and the vacuum unit, and a pneumatic valve is arranged at the vacuum port at the upper end of the filter 4; the air port at the upper end of the filter 4 is connected with an instrument air source distribution device 31 through a pipeline, and the instrument air source distribution device 31 is respectively provided with an instrument air pipeline with the diameter of 4-12mm, a pneumatic valve air pipeline, a balance valve air pipeline and a counter-blowing pipeline with the diameter of 20-38.
Preferably, the crystal temporary storage tank 6 and the mixing tank 9 are respectively provided with a sight hole lamp, a tank cover, a stirring device and a heat preservation jacket, the tank cover is provided with an observation hole, the discharge holes of the crystal temporary storage tank 6 and the mixing tank 9 are respectively provided with an electric regulating valve, the electric regulating valves are connected with a low-temperature screw pulverizer through flexible connection, the low-temperature screw pulverizer is respectively provided with an air inlet filter 32 on a pulverizer fixed cutter head and a movable cutter head, and a 0.45mm prefilter and a 0.01mm sterile fine filter are arranged in the air inlet filter.
Preferably, the upper part of the cyclone separator 8 is connected with an induced draft fan 33 through a pipeline, and the induced draft fan 33 is connected with a water curtain dust removal system 34 through a pipeline; the feeding pipeline in the feeding bin 11 enters the feeding bin 3-5cm, and the discharging pipe in the feeding bin is 3-5cm away from the bottom.
Preferably, the automatic collecting, crushing and packaging system for the dextran biomacromolecule finished product is further provided with a cleaning system, the cleaning system comprises a superheated water system 29 and a pure water system 30, water outlets of the superheated water system 29 and the pure water system 30 are respectively connected with water inlets of a storage bin 3, a crystal temporary storage tank 6, a mixing tank 9 and a filter 4 through pipelines, ball valves are arranged on the pipelines at the water outlets of the superheated water system 29 and the pure water system 30, pneumatic valves are arranged at the water inlets of the storage bin 3, the crystal temporary storage tank 6, the mixing tank 9 and the filter 4, spray pipes 27 are arranged in the storage bin 3, the crystal temporary storage tank 6, the mixing tank 9 and the filter 4, spray heads 28 are arranged on the spray pipes 27 and are connected with the water inlets, spray heads in the storage bin 3 and the filter 4 are fan-shaped 60-degree spray heads, spray heads in the crystal temporary storage tank 6 and the mixing tank 9 are 360-degree rotary spray heads, an emptying valve 12 is arranged in front of an electric control valve below the crystal temporary storage tank 6 and the mixing tank 9, and an emptying valve is arranged on the pipeline of the low-temperature spiral crusher 7 and the cyclone separator 10 are connected with the pipeline.
Preferably, the automatic collecting, crushing and packaging system for the dextran biomacromolecule finished product further comprises a control system, the control system comprises a controller data communication system, the pneumatic valve, the electric regulating valve, the balance valve, the vacuum detector and the air volume detector are electrically connected with the controller data communication system, the controller data communication system comprises a detector transmitter, the pneumatic valve, the electric regulating valve and a balance valve actuator, the controller data communication system is connected with an operation microcomputer, the control system can realize on-site control, and further can realize on-line remote control of the computer.
Example 2
A method for automatically collecting, crushing and packaging a dextran biomacromolecule finished product is characterized in that: the automatic collection, crushing and packaging system comprises the following steps:
(1) Drying 1000 crystals of dextran biological macromolecules in a dryer until the viscosity is 5-10 ten thousand centipoise, feeding the crystals into a pendulum type coarse crusher for coarse crushing, enabling the particle size of the coarse crushed particles to be 3-4 mm, feeding the coarse crushed particles into a 0.22-micrometer sterile titanium rod filter for filtering through a vacuum feeding pipeline, setting the back blowing control interval time to be 100-600 seconds, and carrying out back blowing operation on the 0.22-micrometer sterile titanium rod filter through an instrument air source distribution device;
(2) The particles enter a crystal temporary storage tank through a shut-down fan to be stirred, then enter a low-temperature spiral crusher to be finely crushed with 120-300 meshes, enter a mixing tank to be stirred and mixed after being separated by a cyclone separator, and then are sieved by a vibration sieving machine to obtain a finished product;
(3) After entering the feeding bin, the finished product enters the packaging bin after being separated by the cyclone separator through the feeding pipe, and then enters the metal detector and the automatic packaging machine respectively under the action of the fan to finish packaging.

Claims (7)

1. The utility model provides a dextran biological macromolecule finished product automatic collection smashes package system, its characterized in that, including desiccator (1), the discharge gate of desiccator (1) communicates with the feed inlet of rubbing crusher (2), the discharge gate of rubbing crusher (2) is connected with the feed inlet of feed bin (3) through the pipeline, the vacuum port of feed bin (3) upper end is connected with vacuum system through the pipeline, the gas port of feed bin (3) upper end is connected with Roots blower system through the pipeline, the discharge gate of feed bin (3) is connected with the feed inlet of filter (4) through vacuum material loading pipeline, the discharge gate of filter (4) is connected with pass through pipeline and gate fan (5), gate fan (5) is connected with the feed inlet of crystal temporary storage tank (6), the discharge gate of crystal temporary storage tank (6) is connected with the feed inlet of low temperature screw crusher (7) through the pipeline, the discharge gate of low temperature screw crusher (7) is connected with the feed inlet of cyclone (8) through the vacuum material loading pipeline, cyclone (8) is connected with the feed inlet of separator (9 through the pipeline and gate of mixing drum (10) through the pipeline and mix bin (10) is connected with the feed inlet of sieve (10), the discharging port of the feeding bin (11) is connected with the feeding port of the cyclone separator through a vacuum feeding pipeline, the discharging port of the cyclone separator is connected with the feeding port of the packaging bin (13) through a pipeline, the discharging port of the packaging bin (13) is connected with a closing fan through a pipeline, the closing fan is connected with the feeding port of the metal detector (14), and the discharging port of the metal detector (14) is connected with the automatic packaging machine (15) through a pipeline; the vacuum system comprises a vacuum unit (20), wherein the vacuum unit (20) is respectively connected with two groups of 0-01-micrometer sterile filters (21) through pipelines, the sterile filters (21) are respectively connected with vacuum ports at the upper end of a storage bin (3) through pipelines, ball valves are arranged on pipelines at the air inlet and the air outlet of the sterile filters (21), a pneumatic air valve is arranged on a pipeline at the vacuum port at the upper end of the storage bin (3), and a vacuum detector (22) and a balance valve (23) are arranged on a pipeline between the sterile filters (21) and the storage bin (3); the Roots blower system comprises a Roots blower set (25), the Roots blower set (25) is respectively connected with two groups of 0-01-micrometer sterile filters through pipelines, the sterile filters are respectively connected with air ports at the upper end of a storage bin (3) through pipelines, ball valves are arranged on pipelines at the air inlet and the air outlet of the sterile filters, an air distribution valve is arranged on the pipeline at the air port at the upper end of the storage bin (3), and an air volume detector (26) and a balance valve are arranged on the pipeline between the sterile filters and the storage bin (3); the material conveying is realized through the opening exchange of the vacuum pneumatic valve and the air distribution valve; the utility model discloses a crystal temporary storage tank, including crystal temporary storage tank (6), mixing tank (9), crystal temporary storage tank (6) and mixing tank (9), all be provided with sight glass lamp, cover, agitating unit and heat preservation jacket on crystal temporary storage tank (9), be provided with the observation hole on the cover, the discharge gate department of crystal temporary storage tank (6) and mixing tank (9) all is provided with electric control valve, and electric control valve links to each other with low temperature screw pulverizer through the flexible coupling, is provided with air inlet filter (32) on pulverizer fixed blade disc, movable blade disc on the low temperature screw pulverizer respectively, install 0, 45mm prefilter and 0, 01mm aseptic smart filter in the air inlet filter.
2. The automatic collecting, crushing and packaging system for the finished dextran biomacromolecule product according to claim 1, wherein the automatic collecting, crushing and packaging system is characterized in that: the utility model discloses a pneumatic type pneumatic crusher is characterized in that two storage bins (3) and two filters (4) are respectively arranged, the filters (4) are 0, 22 microns of sterile titanium rod filters, the crusher (2) is a pendulum type coarse crusher, a quick-open type observation maintenance hole (16) is formed in the crusher (2), a pneumatic butterfly valve is arranged on a pipeline between the crusher (2) and a feed inlet of the storage bins (3), a pneumatic ball valve is arranged on a pipeline at a discharge outlet of the storage bins (3), a cleaning discharge outlet (24) is formed in a vacuum feeding pipeline between the storage bins (3) and the filters (4), a jar (17), a vision hole lamp (18) and a quick-open type observation maintenance hole (16) are formed in the storage bins (3), and wheels (19) with brake pads are arranged at the bottoms of the storage bins (3).
3. The automatic collecting, crushing and packaging system for the finished dextran biomacromolecule product according to claim 1, wherein the automatic collecting, crushing and packaging system is characterized in that: the vacuum port at the upper end of the filter (4) is connected with a vacuum unit (20) through a pipeline, a balance valve and a vacuum detector are arranged on the pipeline between the vacuum port and the vacuum unit, and a pneumatic valve is arranged at the vacuum port at the upper end of the filter (4); the air port at the upper end of the filter (4) is connected with an instrument air source distribution device (31) through a pipeline, and the instrument air source distribution device (31) is respectively provided with an instrument air pipeline with the diameter of 4-12mm, a pneumatic valve air pipeline, a balance valve air pipeline and a back-blowing pipeline with the diameter of 20-38.
4. The automatic collecting, crushing and packaging system for the finished dextran biomacromolecule product according to claim 1, wherein the automatic collecting, crushing and packaging system is characterized in that: the upper part of the cyclone separator (8) is connected with an induced draft fan (33) through a pipeline, and the induced draft fan (33) is connected with a water curtain dust removal system (34) through a pipeline; the feeding pipeline in the feeding bin (11) enters 3-5cm of the feeding bin, and the discharging pipe in the feeding bin is 3-5cm away from the bottom.
5. The automatic collecting, crushing and packaging system for the finished dextran biomacromolecule product according to claim 1, wherein the automatic collecting, crushing and packaging system is characterized in that:
Still be provided with cleaning system, cleaning system includes overheated water system (29) and pure water system (30), the delivery port of overheated water system (29) and pure water system (30) is connected with the water inlet on feed bin (3), crystal temporary storage tank (6), blending tank (9), filter (4) respectively through the pipeline, all be provided with the ball valve on the pipeline of the delivery port department of overheated water system (29) and pure water system (30), feed bin (3), crystal temporary storage tank (6), blending tank (9), filter (4) water inlet department all is provided with the pneumatic valve, all be provided with shower (27) in feed bin (3), crystal temporary storage tank (6), blending tank (9), filter (4), be provided with shower (28) on shower (27), shower (27) are connected with the water inlet, the shower nozzle in feed bin (3) and the filter (4) is fan-shaped 60 degrees shower head, the shower nozzle in crystal temporary storage tank (6) and the blending tank (9) is 360 degrees rotatory heads, establishes on the cyclone separator (10) of the low-temperature separator that the motor-driven air separator of setting up in front of the low-temperature adjustment valve (12) and blending tank (4).
6. The automatic collecting, crushing and packaging system for the finished dextran biomacromolecule product according to any one of claims 1 to 5, which is characterized in that: the control system comprises a controller data communication system, wherein the pneumatic valve, the electric regulating valve, the balance valve, the vacuum detector and the air volume detector are electrically connected with the controller data communication system, the controller data communication system comprises a detector transmitter, the pneumatic valve, the electric regulating valve and a balance valve actuator, the controller data communication system is connected with an operation microcomputer, the control system can realize field control, and further can realize computer online remote control.
7. A method for automatically collecting, crushing and packaging a dextran biomacromolecule finished product is characterized in that: completed by the automatic collection and crushing packaging system according to any one of claims 1 to 6, comprising the following steps:
(1) Drying 1000 crystals of dextran biological macromolecules in a dryer until the viscosity is 5-10 ten thousand centipoise, coarse pulverizing in a pendulum coarse pulverizer, coarse pulverizing to obtain particles with particle diameter of 3-4 mm, and filtering with 0, 22 μm sterile titanium rod filter via vacuum feeding pipeline;
(2) The particles enter a crystal temporary storage tank through a shut-down fan to be stirred, then enter a low-temperature spiral crusher to be finely crushed with 120-300 meshes, enter a mixing tank to be stirred and mixed after being separated by a cyclone separator, and then are sieved by a vibration sieving machine to obtain a finished product;
(3) After entering the feeding bin, the finished product enters the packaging bin after being separated by the cyclone separator through the feeding pipe, and then enters the metal detector and the automatic packaging machine respectively under the action of the fan to finish packaging.
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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108946175B (en) * 2018-07-26 2023-08-25 常州朗脉洁净技术有限公司 Continuous discharging system for material dust of vacuum belt dryer
CN112078872A (en) * 2020-09-13 2020-12-15 雷增社 Agricultural chemical fertilizer production equipment for packing device

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0201338A2 (en) * 1985-05-10 1986-11-12 The Babcock & Wilcox Company Coal-water fuel production
JP2008012458A (en) * 2006-07-07 2008-01-24 M & K:Kk Powder and granular material treatment facility
CN102407186A (en) * 2011-11-28 2012-04-11 河南省康星药业有限公司 Traditional Chinese medicine superfine powder sieve linkage system
CN202670746U (en) * 2012-05-31 2013-01-16 开封万盛新材料有限公司 Automatic micro-powder feeding system
CN203184068U (en) * 2013-04-12 2013-09-11 江苏华信塑业发展有限公司 High-efficiency grinding system
CN204648907U (en) * 2015-05-06 2015-09-16 山东金朗生物科技有限公司 A kind of biological polyoses spray drying tower automatic feeding
CN204914285U (en) * 2015-07-20 2015-12-30 江苏锐升新材料有限公司 A automatic compounding system for PVC floor production line
CN105498258A (en) * 2015-12-31 2016-04-20 山东金朗生物科技有限公司 Spray drying system
CN205461921U (en) * 2016-01-26 2016-08-17 浙江德清美史乐颜料科技有限公司 Pigment processing lines
CN106040356A (en) * 2016-07-20 2016-10-26 福建中科康膳生物科技有限公司 Micron-grade wheat bran powder producing and processing device
CN106516309A (en) * 2016-12-29 2017-03-22 江苏金旺包装机械科技有限公司 Pesticide water dispersible granule processing and packaging stereo-distribution composite workshop
CN107051960A (en) * 2017-06-06 2017-08-18 科威嘉粉末涂料(天津)股份有限公司 A kind of powdery paints is from dynamic auxiliary purging system
CN206552867U (en) * 2017-02-21 2017-10-13 山东金朗生物科技有限公司 A kind of L crystalline alanines liquid centrifuges conveying device
CN207725724U (en) * 2017-12-21 2018-08-14 山东金朗生物科技有限公司 Dextran large biological molecule finished product collects crushing packing system automatically

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2014116670A (en) * 2014-04-23 2015-10-27 Петров Алексей Иванович METHOD FOR COMPREHENSIVE PROCESSING OF BROWN COAL AND LEONARDITIS IN HUMIC FERTILIZERS, PREPARATIONS AND IN FUEL BRIQUETTES AND MECHANOCHEMICAL REACTOR FOR PROCESSING HIGH-VISCOUS MEDIA
US10369575B2 (en) * 2015-08-21 2019-08-06 Urban Mining Northeast, Llc Process for cleaning dirty post-consumer waste glass

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0201338A2 (en) * 1985-05-10 1986-11-12 The Babcock & Wilcox Company Coal-water fuel production
JP2008012458A (en) * 2006-07-07 2008-01-24 M & K:Kk Powder and granular material treatment facility
CN102407186A (en) * 2011-11-28 2012-04-11 河南省康星药业有限公司 Traditional Chinese medicine superfine powder sieve linkage system
CN202670746U (en) * 2012-05-31 2013-01-16 开封万盛新材料有限公司 Automatic micro-powder feeding system
CN203184068U (en) * 2013-04-12 2013-09-11 江苏华信塑业发展有限公司 High-efficiency grinding system
CN204648907U (en) * 2015-05-06 2015-09-16 山东金朗生物科技有限公司 A kind of biological polyoses spray drying tower automatic feeding
CN204914285U (en) * 2015-07-20 2015-12-30 江苏锐升新材料有限公司 A automatic compounding system for PVC floor production line
CN105498258A (en) * 2015-12-31 2016-04-20 山东金朗生物科技有限公司 Spray drying system
CN205461921U (en) * 2016-01-26 2016-08-17 浙江德清美史乐颜料科技有限公司 Pigment processing lines
CN106040356A (en) * 2016-07-20 2016-10-26 福建中科康膳生物科技有限公司 Micron-grade wheat bran powder producing and processing device
CN106516309A (en) * 2016-12-29 2017-03-22 江苏金旺包装机械科技有限公司 Pesticide water dispersible granule processing and packaging stereo-distribution composite workshop
CN206552867U (en) * 2017-02-21 2017-10-13 山东金朗生物科技有限公司 A kind of L crystalline alanines liquid centrifuges conveying device
CN107051960A (en) * 2017-06-06 2017-08-18 科威嘉粉末涂料(天津)股份有限公司 A kind of powdery paints is from dynamic auxiliary purging system
CN207725724U (en) * 2017-12-21 2018-08-14 山东金朗生物科技有限公司 Dextran large biological molecule finished product collects crushing packing system automatically

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
何志成.制剂单元操作与制剂工程设计.北京中国医药科技出版社,2006,(第1版),181-187. *
全自动CIP清洗系统综述;卢成雷;中国乳业(第176期);62-67 *
刘广文.干燥设备选型及采购指南.中国石化出版社,2004,(第第一版版),117-120. *
真空冷冻干燥的现状与展望(二);徐成海;张世伟;彭润玲;张志军;;真空(第03期);全文 *
降低无菌原料药污染风险的技术措施;周立法;;机电信息;20131215(第35期);全文 *

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