CN107744468A - A kind of radioisotope solution capsule auto-loading system and method for filling - Google Patents
A kind of radioisotope solution capsule auto-loading system and method for filling Download PDFInfo
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- CN107744468A CN107744468A CN201610742473.8A CN201610742473A CN107744468A CN 107744468 A CN107744468 A CN 107744468A CN 201610742473 A CN201610742473 A CN 201610742473A CN 107744468 A CN107744468 A CN 107744468A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/078—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of wafers or cachets
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Abstract
The present invention relates to a kind of radioisotope solution capsule auto-loading system and automatic subpackaging method.The system includes supporting table and the shielding hot cell being installed in supporting table；Packing platform is provided with hot cell, packing platform is provided with robot, packaging device, pre-filled capsule pallet component, the Recycling Mother Solution device being connected by power set with packaging device；Robot, packaging device and power set are connected with controller, and controller controls above-mentioned component to be acted to realize that decoction capsule automatic ration dispenses according to decoction and patient profiles.Automaticity height, production efficiency height, high, easy to operate, advantages of good shielding performance the isotope decoction capsule auto-loading system of packing precision and method for filling of the present invention, this set system can select economic model or high effective model simultaneously, bigger selection space is provided for different demands user, there is huge application value.
Description
Technical field
The present invention relates to medicine dispense field, and in particular to a kind of radioisotope solution capsule auto-loading system and
Method for filling.
Background technology
Radio isotope medicine is widely used to clinic, and many methods can all realize the automatic dilution of isotope decoction
Packing, but they dispense it is latter as finally take to patient is oral administration solution；Oral administration solution has many drawbacks, such as counterpart
The pollution of chamber, esophagus etc. and damage problem, in order to solve these problems, domestic and foreign scholars propose replaces oral administration solution with capsule
Scheme.
But the production of current radioisotope solution capsule is substantially or artificial packing, the artificial capsule method that dispenses are deposited
In following problem：
A, isotope drug ingedient dosage is inaccurate in capsule：It is too low, therapeutic effect is influenceed, it is too high, it may cause to patient
Injury；
B, the safeguard procedures for dispensing personnel are improper：If protection is enough, manipulation strength is big;If reducing manipulation strength, radiate
Property protective is poor, and operating personnel's stress is big；
C, it is low to dispense efficiency；
D, and the problems such as the relevant information statistical difficulty of patient.
The content of the invention
It is existing to solve it is an object of the present invention to provide a kind of radioisotope solution capsule auto-loading system
Isotope decoction capsule can not realize automation packing and existing packing technology is inaccurate, efficiency is low and protection improperly
Measure.
It is a further object to provide automatic point of above-mentioned radioisotope solution capsule auto-loading system
Dress method.
The technical scheme that the present invention solves above-mentioned technical problem is as follows：A kind of radioisotope solution capsule automatic subpackaging
System, including supporting table and the shielding hot cell that is installed in supporting table；
Packing platform is provided with the hot cell, the packing platform is provided with robot, packaging device, pre-filled capsule tray set
Part, the Recycling Mother Solution device being connected by power set with the packaging device；
The robot, packaging device and power set are connected with controller, and the controller is according to decoction and patient's feelings
Condition controls above-mentioned component to be acted to realize that decoction capsule automatic ration dispenses.
On the basis of above-mentioned technical proposal, the present invention can also do following improvement.
Further, the radioisotope solution capsule auto-loading system is also respectively arranged at shielding heat including two
Room side and the shielding transfer device of lower end.
Further, the shielding transfer device transmits drawer for shielding transfer chamber or shielding；Set in the shielding transfer chamber
There is side room shield door；The shielding transmits drawer and is provided with shielding drawer cover plate.
Further, the lifting device being connected with controller is additionally provided with the packing platform, is gone back on auto-loading system
Provided with activity measurement equipment, lifting device matches with activity measurement equipment to be connected；
The activity measurement equipment includes ionization well and the activity meter being connected with the ionization well.
Further, the lifting device includes lifting device bracket and is vertically connected at the lifting of the lifting device bracket
Appliance stand；At least one positioning hole is provided with the lifting device bracket.
Further, the packaging device includes packaging device main body, the packing pin being arranged in the packaging device main body
Base and the packing pin being fixed on the packing pin base.Further, the packaging device also includes being arranged at the packing
It is used to drive the contact pin drive device of the packing pin base motions on apparatus main body, is arranged under the packaging device main body
The hold assembly for being used to grip capsule on base.
Further, the Recycling Mother Solution device includes mother liquid multi-cavity bottle, the mother liquor cask flask for placing mother liquid multi-cavity bottle and is plugged in
Liquid pin, backflow pin and exhaust needle are taken on mother liquid multi-cavity bottle；It is described to take liquid pin to be then connected to after being connected by pipeline with power set
Packaging device；The backflow pin is connected with packaging device.
Further, the pre-filled capsule pallet component also includes cask flask and cask flask plug.
Further, hot cell shield door and the organic glass door with glove hole, the heat are additionally provided with the shielding hot cell
Room shield door is provided with protected type hagioscope.
Further, the power set are the pump group being made up of one or several peristaltic pumps.
The automatic subpackaging method of above-mentioned radioisotope solution capsule auto-loading system, including：
According to isotope decoction mother liquor and patient data, decoction packing dosage requirements data are calculated, and above-mentioned data are defeated
Go out to controller；
Recycling Mother Solution device and pre-filled capsule pallet component are arranged respectively so that radioisotope solution mother liquor, pre-filled
Capsule prepares in place；
Controller control machine people grips pre-filled capsule from pre-filled capsule pallet component, and is moved to packaging device progress
Packing, isotope liquid medicine quantitative is injected in pre-filled capsule；
The manipulator of controller control machine people grips pre-filled capsule from pre-filled capsule pallet component, and is moved to packing
Device, while coordinated signals power set are dispensed, so as to which isotope liquid medicine quantitative is injected in pre-filled capsule.
Further, the automatic subpackaging method of radioisotope solution capsule auto-loading system also includes：
Isotope capsule to lifting device, lifting device after the manipulator clamping filling of controller control machine people again will filling
Isotope capsule transport to measuring in activity measurement equipment；
By measurement result compared with the decoction packed dose data that initial calculation obtains, if packing is correct, robot
Capsule is directly clamped into decoction capsule tank tray set；
By measurement result compared with the decoction packing dosage requirements data that initial calculation obtains, if packing is correct, control
Robot processed directly clamps capsule into the cask flask of pre-filled capsule pallet component and covers shield plug；
If packing is incorrect, control machine people clamp capsule into pre-filled capsule pallet component pre-filled capsule it is initial
Position, whole capsule subpackages are waited to be modified again after terminating.
Further, the specific method of arrangement Recycling Mother Solution device and pre-filled capsule pallet component successively is：
Pull out protected type and transmit drawer, mother liquor cask flask is put into, close protected type and transmit drawer；
Side room shield door is opened, pre-filled capsule pallet component is inserted in shielding transfer chamber, closes side room shield door；
Hot cell shield door is opened, by the glove hole on the organic glass door with glove hole, shielding drawer cover plate is opened, by mother
Liquid cask flask takes out, and then covers shielding drawer cover plate, then will take liquid pin, backflow pin and exhaust needle insertion mother liquid multi-cavity bottle；
Pre-filled capsule pallet component is taken out again, predeterminated position is slid into and fixes, be then shut off hot cell shield door.
Further, use the specific method that packaging device is dispensed for：
The manipulator of robot grips pre-filled capsule from pre-filled capsule pallet component, moves to packaging device station, machinery
Pre-filled capsule is placed in the positioning of capsule positioning hole by hand, and gripping apparatus grips fix pre-filled capsule, the driving of contact pin drive device
Dispense pin base and packing pin inserts pre-filled capsule；Dosage requirements data are dispensed according to decoction, power set are by volumetric soiutions
Injected by dispensing pin in pre-filled capsule；
After fluid injection terminates, contact pin drive device driving packing pin base and packing pin are extracted and resetted from pre-filled capsule.
Further, use the specific method that packaging device is dispensed for：
The manipulator of robot grips pre-filled capsule from pre-filled capsule pallet component, moves to packaging device station, machinery
Hand clamps pre-filled capsule and moved to pan-up, until pre-filled capsule is by packing needle-penetration；Dosage requirements are dispensed according to decoction
Data, power set inject quantitative isotope decoction in pre-filled capsule by dispensing pin；
After fluid injection terminates, the pre-filled capsule of manipulator clamping is extracted from packing pin.
The present invention is by setting by robot and the packaging device, power set and the Recycling Mother Solution device that are controlled by controller
Deng the auto-loading system of composition, the full-automatic and controllable of radioisotope solution capsule subpackage is realized in a creative way
Change so that radio isotope capsule product realize can Flexible Production, meanwhile, as needed, can every glue of adjust automatically
The dosage of capsule, it have effectively achieved safe, the accurate and automated production of radioactive capsule production.
Using the auto-loading system of the present invention, greatly reducing the nuclear radiation on operating personnel influences, and effectively increases
The security of production process；Meanwhile the packing of capsule is effectively carried out according to result of calculation, can also be adjusted automatically according to production process
The dosage of whole every capsule, packing precision is higher, and flexibility is more preferable, and then also substantially increases production efficiency.
The system is by setting the packaging device of different structure so that packing process can be in economic model and high effective model
Between switch, provide the user bigger selection space, reduce part accessory, reduce cost.
Brief description of the drawings
Fig. 1 is the main structure chart of radioisotope solution capsule auto-loading system of the present invention；
Fig. 2 is the part-structure figure of radioisotope solution capsule auto-loading system of the present invention；
Fig. 3 is the structural representation of packing platform；
Fig. 4 is the structural representation of lifting device；
Fig. 5 is structural representation of the packaging device under high effective model；
Fig. 6 is the structural representation of packaging device in the economy mode.
In accompanying drawing, the list of parts representated by each label is as follows：
1st, hot cell is shielded；11st, protected type hagioscope；12nd, hot cell shield door；13rd, organic glass door；14th, side room isolating door；15、
Dispense platform；151st, lifting device；1511st, lifting device bracket；1512nd, lifting device support；1513rd, positioning hole；152nd, divide
Assembling device；1521st, contact pin drive device；1522nd, packaging device main body；1523rd, hold assembly；1524th, capsule positioning hole；
1525th, pin is dispensed；1526th, pin base is dispensed；153rd, Recycling Mother Solution device；1531st, liquid pin is taken；1532nd, flow back pin；1533rd, arrange
Air tube；1534th, mother liquid multi-cavity bottle；1535th, mother liquor cask flask；154th, peristaltic pump；155th, robot；1551st, manipulator；156th, it is pre-filled
Capsule pallet component；1561st, cask flask plug；1562nd, cask flask；1563rd, pallet；2nd, supporting table；3rd, drawer is transmitted in shielding；31、
Shield drawer cover plate；4th, transfer chamber is shielded；41st, side room shield door；5th, activity meter；6th, well is ionized；7th, controller；8th, shading ring.
Embodiment
The principle and feature of the present invention are described below in conjunction with accompanying drawing, the given examples are served only to explain the present invention, and
It is non-to be used to limit the scope of the present invention.
Embodiment 1：Radioisotope solution capsule auto-loading system
According to one embodiment of the application, as depicted in figs. 1 and 2, radioisotope solution capsule auto-loading system bag
Supporting table 2 is included, shielding hot cell 1 is provided with supporting table 2, the right side in shielding hot cell 1 is provided with shielding transfer chamber 4, shielding hot cell 1
Lower end is provided with shielding and transmits drawer 3；Shielding transfer chamber 4 is provided with side room shield door 41；Shielding transmits drawer 3 and is provided with shielding
Drawer cover plate 31；Shielding is additionally provided with hot cell shield door 12 and the organic glass door 13 with glove hole, hot cell shield door on hot cell 1
12 are provided with protected type hagioscope 11；Shielding transfer chamber 4 is provided with side room isolating door 14 with the shielding connection of hot cell 1；Shielding heat
The outside of room 1 is also provided with activity measurement equipment；Activity measurement equipment includes the ionization being installed in the lower space of supporting table 2
Well 6 and the activity meter 5 being arranged at outside shielding hot cell；Shading ring 8 is also provided with the space of the bottom of supporting table 2, ionizes well 6
The part stretched out outside shielding hot cell is wrapped up by shading ring, with anti-nuclear radiation.
As shown in figure 3, being provided with packing platform 15 in shielding hot cell 1, packing platform 15 is provided with robot 155, packing dress
Put 152, pre-filled capsule pallet component 156, power set and Recycling Mother Solution device 153；It is provided with the space of the bottom of supporting table 2
Controller 7；Robot 155, packaging device 152 and power set are connected with controller 7；Wherein, robot 155 is provided with
Manipulator 1551, it is controlled to be acted by controller 7；
In one embodiment of the application, dispense in platform 15 and be also provided with lifting device 151, itself and activity measurement equipment
Supporting connection measures for the decoction capsule after packing, and carries out related amendment according to measurement result；As shown in figure 4, carry
Rise device 151 to be made up of with the lifting device support 1512 for being vertically connected at lifting device bracket lifting device bracket 1511, carry
Rise in device bracket 1511 and be provided with one or several positioning holes 1513.
As shown in figure 5, in one embodiment of the application, packaging device 152 can by packaging device main body 1522, set
The packing pin base 1526 that is placed in packaging device main body, the packing pin 1525 being fixed on packing pin base, for driving point
Fill pin base motions contact pin drive device 1521, be arranged on the lower bottom base of packaging device main body be used for grip capsule
Hold assembly 1523 and capsule positioning hole 1524 form, under this structure, auto-loading system can be under high effective model
Produced, detailed process is：
Manipulator 1551 grips pre-filled capsule from pre-filled capsule pallet component 156, moves to the station of packaging device 152, machine
Pre-filled capsule is placed in capsule positioning hole 1524 and positioned by tool hand 1551, and manipulator leaves, and hold assembly 1523 grips pre-
Capsule is filled, the driving packing pin of contact pin drive device 1521 base 1526 and packing pin 1525 insert pre-filled capsule；According to meter
Result is calculated, power set inject volumetric soiutions in pre-filled capsule by dispensing pin 1525；
After fluid injection terminates, the driving packing pin of contact pin drive device 1521 base 1526 and packing pin 1525 pull out from the capsule having been filled with
Go out and reset, complete the high effective model of packing.
As shown in fig. 6, in one embodiment of the application, packaging device can be by packaging device main body 1522, setting
Formed in the packing pin base 1526 in packaging device main body and the packing pin 1525 being fixed on packing pin base, in the structure
Under, auto-loading system can be produced in the economy mode, and detailed process is：
Manipulator 1551 grips pre-filled capsule from pre-filled capsule pallet component 156, moves to the station of packaging device 152；
The station of packaging device 152, manipulator 1551 clamp pre-filled capsule and moved to pan-up, until pre-filled capsule is by packing pin
1525 pierce through；According to result of calculation, power set inject volumetric soiutions in pre-filled capsule by dispensing pin 1525；Fluid injection knot
Shu Hou, the clamping of manipulator 1551 have been filled with capsule and extracted from packing pin.
On the basis of said structure, when system includes lifting device, its course of work is：
After the release of hold assembly 1523 has been filled with capsule, the clamping of manipulator 1551 has been filled with capsule to the station of lifting device 151；Machine
Tool hand 1551 is placed in capsule is had been filled with the positioning hole 1513 of lifting device bracket 1511, and manipulator 1551 leaves, lifting dress
Put bracket 1511 carry have been filled with capsule drop to ionization well 6 in measure；After being measured, lifting device bracket 1511 is taken
Band has been filled with capsule and rises to initial position；The decoction packing dosage requirements data that measurement result is obtained with initial calculation are compared
Compared with analysis：
If packing is inaccurate, it is necessary to correct, the clamping of manipulator 1551 has been filled with capsule and placed to pre-filled capsule tray set
Initial position on part 156, whole capsule subpackages are waited to be modified operation after terminating；
If being not required to correct, the clamping of manipulator 1551 has been filled with capsule and put into cask flask 1562, manipulator 1551
The vessel port that cask flask plug 1561 clogs cask flask is clamped again；All capsule manufactures are filled out in pre-filled capsule pallet component 156
Complete, shutdown is charged, opening hot cell shield door 12, passes through the glove hole on the organic glass door 13 with glove hole and opens side room isolation
Door 14, pre-filled capsule pallet component 156 is sent into shielding transfer chamber 4, side room isolating door 14 is closed, opens side room shield door
41, pre-filled capsule pallet component 156 is taken out；So far capsule subpackage entire flow terminates.
In one embodiment of the application, power set can be to form pump group by one or several peristaltic pumps 154,
Packaging device is squeezed into by mother liquid multi-cavity bottle for mother liquor power is provided；In this application, power set can be by 154 groups of a peristaltic pump
Into.
In one embodiment of the application, Recycling Mother Solution device 153 can be by mother liquid multi-cavity bottle 1534, the mother for placing mother liquid multi-cavity bottle
Liquid cask flask 1535, it is inserted on mother liquid multi-cavity bottle and takes liquid pin 1531, backflow pin 1532 and exhaust needle 1533 to form；Wherein, liquid pin is taken
1531 are connected by pipeline with peristaltic pump 154, and backflow pin 1532 is connected with packaging device 152, and exhaust needle 1533 is empty needle head
It is not connected to any equipment；In production, mother liquor cask flask 1535 is entered in shielding hot cell 1 by shielding transmission drawer 3.
In one embodiment of the application, pre-filled capsule pallet component 156 by pallet 1563, be arranged on pallet
Several cask flasks 1562, cask flask plug 1561 and several pre-filled capsule compositions；During production, pre-filled capsule pallet component
156 enter shielding hot cell 1 by shielding transfer chamber 4.
Concrete structure based on above-mentioned Recycling Mother Solution device 153 and pre-filled capsule pallet component 156, divided automatically
During dress, specific operation process is：
Pull out shielding and transmit drawer 3, the mother liquor cask flask 1535 for being placed with mother liquid multi-cavity bottle 1534 is put into above-mentioned drawer, close shielding
Transmit drawer 3；Side room shield door 41 is opened, pre-filled capsule pallet component 156 is inserted, closes side room shield door 41；Open
Hot cell shield door 12, by the gloves hole operation on the organic glass door 13 with glove hole, shielding drawer cover plate 31 is opened, by mother
Liquid cask flask 1535 is taken out, and then covers shielding drawer cover plate 31, and liquid pin 1531, backflow pin 1532, exhaust needle 1533 will be taken to insert
Enter mother liquid multi-cavity bottle 1534, make pipeline in order；Side room isolating door 14 is opened, pre-filled capsule pallet component 156 is taken out, slid into default
Position is fixed, and is then shut off side room isolating door 14, closes hot cell shield door 41, ready.
Embodiment 2：The automatic subpackaging method of radioisotope solution capsule auto-loading system
The automatic subpackaging method of above-mentioned radio isotope capsule auto-loading system can be divided under high effective model and economic mould
The course of work under formula, it is respectively：
1. the course of work under high effective model
According to isotope decoction mother liquor and patient data, the data such as decoction packing dosage requirements, volume are calculated, and will be above-mentioned
Data output is to controller 7；Controller 7 call control machine people and related I after data O Interface end cooperative equipment（Such as machinery
Hand 1551, lifting device 151, power set, Recycling Mother Solution device 153 and packaging device 152 etc.）Dispensed and measured, surveyed
Data are measured through activity measurement device measuring, measurement data is judged, and then controls and is modified or the associative operation such as shipment,
Pre-filled capsule pallet component 156 is taken out into then flow out of shielding transfer chamber 4 after the completion of a collection of capsule manufacture to terminate, specifically
Process is：
Pull out shielding and transmit drawer 3, mother liquid multi-cavity bottle 1534 is put into mother liquor cask flask 1535, then mother liquor cask flask 1535 is put into
In above-mentioned drawer, close shielding and transmit drawer 3；Side room shield door 41 is opened, pre-filled capsule pallet component 156 is inserted, is closed
Close side room shield door 41；Hot cell shield door 12 is opened, by the gloves hole operation on the organic glass door 13 with glove hole, is opened
Drawer cover plate 31 is shielded, mother liquor cask flask 1535 is taken out, then covers shielding drawer cover plate 31, liquid pin 1531, backflow will be taken
Pin 1532 and exhaust needle 1533 insert mother liquid multi-cavity bottle 1534, make pipeline in order；Side room isolating door 14 is opened, by pre-filled capsule tray set
Part 156 takes out, and slides into predeterminated position and fixes, and is then shut off side room isolating door 14, closes hot cell shield door 12.
Manipulator 1551 grips pre-filled capsule from pre-filled capsule pallet component 156, moves to the work of packaging device 152
Pre-filled capsule is placed in capsule positioning hole 1524 and positioned by position, manipulator 1551, and manipulator leaves, and the clamping of hold assembly 1523 is solid
Fixed pre-filled capsule, the driving packing pin of contact pin drive device 1521 base 1526 and packing pin 1525 insert pre-filled capsule；Root
According to result of calculation, peristaltic pump 154 injects volumetric soiutions in pre-filled capsule by dispensing pin 1525；
After fluid injection terminates, the driving packing pin of contact pin drive device 1521 base 1526 and packing pin 1525 are extracted from capsule is had been filled with
And reset；
After the release of hold assembly 1523 has been filled with capsule, the clamping of manipulator 1551 has been filled with capsule to the station of lifting device 151；Machine
Tool hand 1551 is placed in capsule is had been filled with the positioning hole 1513 of lifting device bracket 1511, and manipulator 1551 leaves, lifting dress
Put bracket 1511 carry have been filled with capsule drop to ionization well 6 in measure；Lifting device bracket 1511 carries and has been filled with glue
Capsule rises to initial position；
Measurement result is judged, as packing is inaccurate, it is necessary to correct, the clamping of manipulator 1551 have been filled with capsule place to
Initial position on pre-filled capsule pallet component 156, whole capsule subpackages are waited to be modified operation after terminating；Such as it is not required to repair
Just, then manipulator folder 1551 is held and has been filled with capsule and put into cask flask 1562, and manipulator 1551 clamps cask flask plug again
1561 clog the vessel port of cask flask 1562；All capsule manufacture fillings finish in pre-filled capsule pallet component 156, stop
Machine, hot cell shield door 12 is opened, side room isolating door 14 is opened by the glove hole on the organic glass door 13 with glove hole, will be pre-
Fill capsule pallet component 156 and be sent into shielding transfer chamber 4, close side room isolating door 14, open side room shield door 41, will be pre-filled
Capsule pallet component 156 takes out；So far capsule subpackage entire flow terminates.
2. the course of work under economic model
The course of work under economic model is substantially identical with high effective model, and unique different place is because packing fills
The difference of structure is put, the difference of the caused course of work, when embodiment 1 describes system, has been carried out illustrating, then this, no
Repeat.
In summary, the invention provides a set of automaticity is high, production efficiency is high, packing precision is high, it is easy to operate,
The isotope decoction capsule auto-loading system and method for filling of advantages of good shielding performance, while this set system can select economic model
Or high effective model, bigger selection space is provided for different demands user, there is huge application value.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.
Claims (17)
1. radioisotope solution capsule auto-loading system, it is characterized in that, including supporting table and be installed in supporting table
Shield hot cell；
Packing platform is provided with the hot cell, the packing platform is provided with robot, packaging device, pre-filled capsule tray set
Part, the Recycling Mother Solution device being connected by power set with the packaging device；
The robot, packaging device and power set are connected with controller, and the controller is according to decoction and patient's feelings
Condition controls above-mentioned component to be acted to realize that decoction capsule automatic ration dispenses.
2. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that,
Also include two shielding transfer devices for being respectively arranged at shielding hot cell side and lower end.
3. radioisotope solution capsule auto-loading system according to claim 2, it is characterized in that,
The shielding transfer device transmits drawer for shielding transfer chamber or shielding；The screened room transfer chamber shields provided with side room
Door；The shielding transmits drawer and is provided with shielding drawer cover plate.
4. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that,
The lifting device being connected with controller, the lifting device and activity measurement equipment phase are additionally provided with the packing platform
Supporting connection；
The activity measurement equipment includes ionization well and the activity meter being connected with the ionization well.
5. radioisotope solution capsule auto-loading system according to claim 4, it is characterized in that：The lifting dress
Put including lifting device bracket and the lifting device support for being vertically connected at the lifting device bracket；The lifting device bracket
It is interior to be provided with least one positioning hole.
6. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that,
The packaging device includes packaging device main body, the packing pin base being arranged in the packaging device main body and is fixed on
Packing pin on the packing pin base.
7. radioisotope solution capsule auto-loading system according to claim 6, it is characterized in that, the packing dress
Putting also includes being arranged at the contact pin drive device for being used to drive the packing pin base motions in the packaging device main body, sets
The hold assembly for being used to grip capsule on the lower bottom base of the packaging device main body.
8. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that, the mother liquor follows
Loop device include mother liquid multi-cavity bottle, the mother liquor cask flask for placing mother liquid multi-cavity bottle and be plugged on mother liquid multi-cavity bottle take liquid pin, backflow pin and
Exhaust needle；It is described to take liquid pin to be then connected to packaging device after being connected by pipeline with power set；The backflow pin and packing
Device is connected.
9. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that, it is described pre-filled
Capsule pallet component includes pallet and several the pre-filled capsules being positioned on pallet.
10. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that, the pre-fill
Filling capsule pallet component also includes cask flask and cask flask plug.
11. radioisotope solution capsule auto-loading system according to claim 1, it is characterized in that, the shielding
Hot cell shield door and the organic glass door with glove hole are additionally provided with hot cell, the hot cell shield door is spied on provided with protected type
Window.
12. according to the radioisotope solution capsule auto-loading system described in claim 1, it is characterized in that, the power dress
It is set to the pump group being made up of one or several peristaltic pumps.
13. the automatic subpackaging side of the radioisotope solution capsule auto-loading system described in any one of claim 1 to 12
Method, it is characterized in that, including：
According to isotope decoction mother liquor and patient data, decoction packing dosage requirements data are calculated, and above-mentioned data are defeated
Go out to controller；
Recycling Mother Solution device and pre-filled capsule pallet component are arranged respectively so that radioisotope solution mother liquor, pre-filled
Capsule prepares in place；
Controller control machine people grips pre-filled capsule from pre-filled capsule pallet component, and is moved to packaging device progress
Packing, isotope liquid medicine quantitative is injected in pre-filled capsule；
The manipulator of controller control machine people grips pre-filled capsule from pre-filled capsule pallet component, and is moved to packing
Device, while coordinated signals power set are dispensed, so as to which isotope liquid medicine quantitative is injected in pre-filled capsule.
14. the automatic subpackaging method of the radioisotope solution capsule auto-loading system described in claim 13, its feature
It is, in addition to：
Isotope capsule to lifting device, lifting device after the manipulator clamping filling of controller control machine people again will filling
Isotope capsule transport to measuring in activity measurement equipment；
By measurement result compared with the decoction packed dose data that initial calculation obtains, if packing is correct, robot
Capsule is directly clamped into pre-filled capsule pallet component；
By measurement result compared with the decoction packing dosage requirements data that initial calculation obtains, if packing is correct, control
Robot processed directly clamps capsule into the cask flask of pre-filled capsule pallet component and covers shield plug；
If packing is incorrect, control machine people clamp capsule into pre-filled capsule pallet component pre-filled capsule it is initial
Position, whole capsule subpackages are waited to be modified again after terminating.
15. the automatic subpackaging method of radioisotope solution capsule auto-loading system according to claim 13, its
It is characterized in, the specific method of the arrangement Recycling Mother Solution device and pre-filled capsule pallet component is：
Pull out protected type and transmit drawer, mother liquor cask flask is put into, close protected type and transmit drawer；
Side room shield door is opened, pre-filled capsule pallet component is inserted in shielding transfer chamber, closes side room shield door；
Hot cell shield door is opened, by the glove hole on the organic glass door with glove hole, shielding drawer cover plate is opened, by mother
Liquid cask flask takes out, and then covers shielding drawer cover plate, then will take liquid pin, backflow pin and exhaust needle insertion mother liquid multi-cavity bottle；
Pre-filled capsule pallet component is taken out again, predeterminated position is slid into and fixes, be then shut off hot cell shield door.
16. the automatic subpackaging method of radioisotope solution capsule auto-loading system according to claim 13, its
Be characterized in, use the specific method that packaging device is dispensed for：
The manipulator of robot grips pre-filled capsule from decoction capsule tank tray set, moves to packaging device station, manipulator
Pre-filled capsule is placed in the positioning of capsule positioning hole, gripping apparatus grips fix pre-filled capsule, the driving point of contact pin drive device
Fill pin base and packing pin inserts pre-filled capsule；According to result of calculation, pump is pre-filled by dispensing pin injection by volumetric soiutions
In capsule；
The manipulator of robot grips pre-filled capsule from pre-filled capsule pallet component, moves to packaging device station, machinery
Pre-filled capsule is placed in the positioning of capsule positioning hole by hand, and gripping apparatus grips fix pre-filled capsule, the driving of contact pin drive device
Dispense pin base and packing pin inserts pre-filled capsule；Dosage requirements data are dispensed according to decoction, power set are by volumetric soiutions
Injected by dispensing pin in pre-filled capsule；
After fluid injection terminates, contact pin drive device driving packing pin base and packing pin are extracted and resetted from pre-filled capsule.
17. the automatic subpackaging method of radioisotope solution capsule auto-loading system according to claim 13, its
Be characterized in, use the specific method that packaging device is dispensed for：
The manipulator of robot grips pre-filled capsule from pre-filled capsule pallet component, moves to packaging device station, machinery
Hand clamps pre-filled capsule and moved to pan-up, until pre-filled capsule is by packing needle-penetration；Dosage requirements are dispensed according to decoction
Data, power set inject quantitative isotope decoction in pre-filled capsule by dispensing pin；
After fluid injection terminates, the pre-filled capsule of manipulator clamping is extracted from packing pin.
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| CN201610742473.8A CN107744468B (en) | 2016-08-29 | 2016-08-29 | Automatic sub-packaging system and sub-packaging method for radioactive isotope liquid medicine capsules |
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| CN201610742473.8A CN107744468B (en) | 2016-08-29 | 2016-08-29 | Automatic sub-packaging system and sub-packaging method for radioactive isotope liquid medicine capsules |
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