CN107496882A - 一种治疗支气管哮喘的丸剂药物及制备方法 - Google Patents

一种治疗支气管哮喘的丸剂药物及制备方法 Download PDF

Info

Publication number
CN107496882A
CN107496882A CN201710888270.4A CN201710888270A CN107496882A CN 107496882 A CN107496882 A CN 107496882A CN 201710888270 A CN201710888270 A CN 201710888270A CN 107496882 A CN107496882 A CN 107496882A
Authority
CN
China
Prior art keywords
root
medicine
chinese
tuber
bark
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201710888270.4A
Other languages
English (en)
Inventor
罗兴贵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Xingjujiao Medical Technology Co Ltd
Original Assignee
Sichuan Xingjujiao Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Xingjujiao Medical Technology Co Ltd filed Critical Sichuan Xingjujiao Medical Technology Co Ltd
Priority to CN201710888270.4A priority Critical patent/CN107496882A/zh
Publication of CN107496882A publication Critical patent/CN107496882A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明属于中药制剂领域，目的是根据中医治疗支气管哮喘的认识机理而提供的一种治疗支气管哮喘的丸剂药物，所述药物的各个组分及其质量份比如下：五味子30～160g、白芷30～160g、地龙50～120g、款冬花50～100g、桔梗30～100g、生姜30～100g、金荞麦150～350g、百部30～120g、麦冬60～120g、辛夷30～120g、桑白皮90～160g、白前30～100g、紫菀50～100g、鹅不食草60～100g、鱼腥草150～350g、前胡30～100g、白果50～90g、陈皮30～160g、人参30～100g、猫爪草150～350g、麻黄25～120g、厚朴30～100g，本发明提供的药物是一个很好的中药组方。

Description

一种治疗支气管哮喘的丸剂药物及制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种治疗支气管哮喘的丸剂药物，特别是供支气管哮喘患者使用的丸剂药物及制备方法的领域。
背景技术
医者认为：支气管哮喘是由多种细胞和细胞组分参与的气道慢性炎症性疾病，这种慢性炎症与气道高反应性相关，通常出现广泛而多变的可逆性气流受限，导致反复发作的喘息、气促、胸闷和（或）咳嗽等症状，多在夜间和（或）清晨发作、加剧，多数患者可自行缓解或经治疗缓解。
临床表现：发作性伴有哮鸣音的呼气性呼吸困难或发作性咳嗽、胸闷。严重者被迫采取坐位或呈端坐呼吸，干咳或咳大量白色泡沫痰，甚至出现发绀等，有时咳嗽可为唯一的症状（咳嗽变异型哮喘）。有的青少年病人则以运动时出现胸闷、咳嗽及呼吸困难为惟一的临床表现（运动性哮喘）。哮喘症状可在数分钟内发作，经数小时至数天，用支气管舒张剂或自行缓解。某些患者在缓解数小时后可再次发作。夜间及凌晨发作和加重常是哮喘的特征之一。
那么，就如何找到一种可有效治疗支气管哮喘的中药组合物，是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗支气管哮喘上，人们逐渐意识到了中医治疗支气管哮喘的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗支气管哮喘的现状，本发明的目的是在于提供一种治疗支气管哮喘的丸剂药物，以解决支气管哮喘患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及其质量份比，可有效治疗上述支气管哮喘。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗支气管哮喘的丸剂药物及制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子30～160g、白芷30～160g、地龙50～120g、款冬花50～100g、桔梗30～100g、生姜30～100g、金荞麦150～350g、百部30～120g、麦冬60～120g、辛夷30～120g、桑白皮90～160g、白前30～100g、紫菀50～100g、鹅不食草60～100g、鱼腥草150～350g、前胡30～100g、白果50～90g、 陈皮30～160g、人参30～100g、猫爪草150～350g、麻黄25～120g、厚朴30～100g，辅料：淀粉适量。
一种治疗支气管哮喘的丸剂药物及制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子38～130g、白芷38～130g、地龙58～105g、款冬花58～90g、桔梗38～90g、生姜38～90g、金荞麦180～320g、百部38～105g、麦冬70～105g、辛夷38～105g、桑白皮100～130g、白前38～90g、紫菀58～90g、鹅不食草70～90g、鱼腥草180～320g、前胡38～90g、白果58～80g、 陈皮38～130g、人参38～90g、猫爪草180～320g、麻黄30～105g、厚朴38～90g，辅料：淀粉适量。
一种治疗支气管哮喘的丸剂药物及制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子115g、白芷115g、地龙95g、款冬花80g、桔梗80g、生姜80g、金荞麦260g、百部95g、麦冬95g、辛夷95g、桑白皮118g、白前80g、紫菀80g、鹅不食草80g、鱼腥草260g、前胡80g、白果70g、 陈皮115g、人参80g、猫爪草260g、麻黄95g、厚朴80g，辅料：淀粉适量。
一种治疗支气管哮喘的丸剂药物及制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比共粉碎成粗粒状包煎；
B、①将包好的原料中药放入冷开水中浸泡60min，然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内，加入原料中药重量6～7 倍的冷开水进行第一次武火煎煮，待煎煮到18min时，转文火熬制130min，滤取药液；②药渣中再次加入原料中药重量5～6 倍的冷开水进行第二次武火煎煮，待煎煮到15min时，转文火熬制130min，滤取药液；③将二次药液混合浓缩成相对密度为1.15的清膏，然后干燥、研磨成极细末备用；
C、①按照传统制备中药水丸剂的方法，将上述极细末和淀粉过筛后，混合均匀，制备成水丸剂（其水丸的粒度为：3.8mm～4.0mm），进而烘干，灭菌，分装密封即可。
一种治疗支气管哮喘的丸剂药物及制备方法，其特征在于，所述服用方法为：将制备好的水丸剂药物以每日三次服用，早中晚各服一次，给药量6g /次，饭后服，21天为一个疗程，服药2～5个疗程，症状得到控制，从而减少了支气管哮喘的发作。
本发明组方中的各原料中药在中国药典、中国辞典以及其中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
五味子，性味：酸、甘、温，具有收敛固涩、益气生津、补肾宁心之功效，用于治疗久泻不止、久咳虚喘、心悸、失眠、多梦、自汗、盗汗、津伤口渴、消渴、遗精、滑精等症；
白芷，性味：性温、味辛、气芳香、微苦，具有祛风湿、活血排脓、生肌止痛之功效，用于治疗头痛、牙痛、鼻渊、肠风痔漏、赤白带下、痈疽疮疡、皮肤瘙痒；
地龙，性味：味咸、性寒，具有清势止痉、平肝熄风、通经活络、平喘利尿之功效，用于治疗热病发热狂燥、惊痫抽搐、肝阳头痛、中风偏瘫、风湿痹痛、肺热喘咳、小便不通等症；
款冬花，性味：辛、微苦、温，具有润肺下气，止咳化痰之功效，用于治疗新久咳嗽、喘咳痰多、劳嗽咳血；
桔梗，性味：性平、味苦、辛，有小毒，具有祛痰、利咽、宣肺、排脓、利五脏、补气血、补五劳、养气之功效，用于治疗咽喉肿痛、肺痈吐脓、咳嗽痰多、痢疾腹痛；
生姜，性味：味辛、性微温，具有解表散寒、温中止呕、温肺止咳、解毒之功效，用于治疗风寒感冒、脾胃寒症、胃寒呕吐、肺寒咳嗽、解鱼蟹毒；
金荞麦，性味：苦、平，具有清热解毒、活血消痈、祛风除湿疮毒、蛇虫咬伤之功效，用于治疗肺痈、肺热咳喘、咽喉肿痛、痢疾、风湿痹证、跌打损伤、痈肿癌；
百部，性味：甘、苦、微温，具有润肺止咳、杀虫灭虱之功效，用于治疗新久咳嗽、肺痨、百日咳、蛲虫病、体虱、癣疥等症；
麦冬，性味：甘、微苦微寒，具有养阴润肺、益胃清心之功效，用于治疗阴虚肺燥、干咳痰稠、劳嗽咯血、津少口渴、心烦失眠、肠燥便秘等症；
辛夷，性味：辛、性温，具有散风寒、通鼻窍之功效，用于治疗鼻渊、风寒感冒之头痛、鼻塞、流涕等症；
桑白皮，性味：甘、辛、性寒，具有泻肺平喘、利水消肿之功效，用于治疗肺热喘痰、水饮停肺、胀满喘急、水肿、脚气、小便不利等症；
白前，性味：辛、苦、微温，具有降气、消痰、止咳之功效，用于治疗肺气壅实、咳嗽痰多、胸满喘急；
紫菀，性味：辛、苦、温，具有润肺下气、消痰止咳之功效，用于治疗痰多喘咳、新久咳嗽、劳嗽咳血；
鹅不食草，性味：味辛、性温，具有发散风寒、通鼻窍、止咳之功效，用于治疗风寒头痛、咳嗽痰多、鼻塞不通、鼻渊流涕；
鱼腥草，性味：味辛、性微寒，具有清热解毒、利尿消肿之功效，用于治疗肺炎、肺脓疡、热痢、疟疾、水肿、淋病、白带、痈肿、痔疮、脱肛、湿疹、秃疮、疥癣等症；
前胡，性味：苦、辛、微寒，具有散风清热，降气化痰之功效，用于治疗风热咳嗽痰多、痰热喘满、咯痰黄稠；
白果，性味：甘、苦、涩、平，有毒， 具有敛肺定喘、止带浊、缩小便之功效，用于治疗痰多喘咳、带下白浊、遗尿尿频；
陈皮，性味：味辛、苦、性温，具有理气和中，燥湿化痰，利水通便之功效，用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等；
人参，性味：性平、味甘、微苦，具有大补元气、复脉固脱、补脾益肺、生津止渴、安神益智之功效，用于治疗劳伤虚损、食少、倦怠、反胃吐食、大便滑泄、虚咳喘促、自汗暴脱、惊悸、健忘、眩晕头痛、阳痿、尿频、消渴、妇女崩漏、小儿慢惊及久虚不复，一切气血津液不足之证；
猫爪草，性味：味甘、辛、性温，具有化痰散结、解毒消肿之功效，用于治疗瘰疬痰核、疔疮肿毒、蛇虫咬伤；
麻黄，性味：辛；微苦、性温，具有发汗解表、宣肺平喘、利水消肿之功效，用于治疗风寒表实证、恶寒发热、无汗、头痛身疼、邪壅于肺、肺气不宣、咳嗽气喘、风水肿、小便不利、风湿痹痛、肌肤不仁以及风疹瘙痒、阴疽痰核；
厚朴， 性味：苦、辛、温，具有燥湿消痰、下气除满之功效，用于治疗湿阻中焦，脘腹胀满，食积气滞，腹胀便秘， 痰饮喘咳；此外，七情郁结，痰气互阻，咽中如有物阻，咽之不下，吐之不出的梅核气证，亦可取本品燥湿消痰，下气宽中之效。
本发明药物是基于中医治疗支气管哮喘的原则，从依据支气管哮喘的病理机制及药理作用认为：就支气管哮喘，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述支气管哮喘的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个很好的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子115g、白芷115g、地龙95g、款冬花80g、桔梗80g、生姜80g、金荞麦260g、百部95g、麦冬95g、辛夷95g、桑白皮118g、白前80g、紫菀80g、鹅不食草80g、鱼腥草260g、前胡80g、白果70g、 陈皮115g、人参80g、猫爪草260g、麻黄95g、厚朴80g，辅料：淀粉适量。
实施例2：
一种治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子130g、白芷130g、地龙105g、款冬花90g、桔梗90g、生姜90g、金荞麦320g、百部105g、麦冬105g、辛夷105g、桑白皮130g、白前90g、紫菀90g、鹅不食草90g、鱼腥草320g、前胡90g、白果80g、 陈皮130g、人参90g、猫爪草320g、麻黄105g、厚朴90g，辅料：淀粉适量。
实施例3：
一种治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子160g、白芷160g、地龙120g、款冬花100g、桔梗100g、生姜100g、金荞麦350g、百部120g、麦冬120g、辛夷120g、桑白皮160g、白前100g、紫菀100g、鹅不食草100g、鱼腥草350g、前胡100g、白果90g、 陈皮160g、人参100g、猫爪草350g、麻黄120g、厚朴100g，辅料：淀粉适量。
典型病例
经临床诊断治疗支气管哮喘患者共1730例，年龄为66岁以上的915例，只有815例为66岁以下。1730例患者中症状得到明显控制的880例，有效的763例，无效的87例。总有效率达95%。

Claims (3)

1.一种治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子30～160g、白芷30～160g、地龙50～120g、款冬花50～100g、桔梗30～100g、生姜30～100g、金荞麦150～350g、百部30～120g、麦冬60～120g、辛夷30～120g、桑白皮90～160g、白前30～100g、紫菀50～100g、鹅不食草60～100g、鱼腥草150～350g、前胡30～100g、白果50～90g、 陈皮30～160g、人参30～100g、猫爪草150～350g、麻黄25～120g、厚朴30～100g，辅料：淀粉适量。
2.根据权利要求1所述的治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子38～130g、白芷38～130g、地龙58～105g、款冬花58～90g、桔梗38～90g、生姜38～90g、金荞麦180～320g、百部38～105g、麦冬70～105g、辛夷38～105g、桑白皮100～130g、白前38～90g、紫菀58～90g、鹅不食草70～90g、鱼腥草180～320g、前胡38～90g、白果58～80g、 陈皮38～130g、人参38～90g、猫爪草180～320g、麻黄30～105g、厚朴38～90g，辅料：淀粉适量。
3.根据权利要求1至2所述的治疗支气管哮喘的丸剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
五味子115g、白芷115g、地龙95g、款冬花80g、桔梗80g、生姜80g、金荞麦260g、百部95g、麦冬95g、辛夷95g、桑白皮118g、白前80g、紫菀80g、鹅不食草80g、鱼腥草260g、前胡80g、白果70g、 陈皮115g、人参80g、猫爪草260g、麻黄95g、厚朴80g，辅料：淀粉适量。
CN201710888270.4A 2017-09-27 2017-09-27 一种治疗支气管哮喘的丸剂药物及制备方法 Withdrawn CN107496882A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710888270.4A CN107496882A (zh) 2017-09-27 2017-09-27 一种治疗支气管哮喘的丸剂药物及制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710888270.4A CN107496882A (zh) 2017-09-27 2017-09-27 一种治疗支气管哮喘的丸剂药物及制备方法

Publications (1)

Publication Number Publication Date
CN107496882A true CN107496882A (zh) 2017-12-22

Family

ID=60699201

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710888270.4A Withdrawn CN107496882A (zh) 2017-09-27 2017-09-27 一种治疗支气管哮喘的丸剂药物及制备方法

Country Status (1)

Country Link
CN (1) CN107496882A (zh)

Similar Documents

Publication Publication Date Title
KR20130014766A (ko) 소아비염 치료용 한약 조성물 및 이의 제조방법
CN103169885A (zh) 一种治疗小儿哮喘的中药组合物
CN102805805A (zh) 一种治疗鼻炎的药物及其制备方法
CN104001045A (zh) 一种用于治疗犬肺炎的药物及其制备方法
CN107375828A (zh) 一种可有效治疗失眠的中药组合物及其制备方法
CN108096344A (zh) 一种治疗鼻炎的中药组合物
CN107737285A (zh) 一种治疗小儿咳嗽的汤剂药物及其制备方法
CN103845718B (zh) 一种治疗咳嗽气喘的药物及制备方法
CN103611005B (zh) 一种治疗慢性咽炎的药物及其制备方法
CN107496882A (zh) 一种治疗支气管哮喘的丸剂药物及制备方法
CN108114220A (zh) 一种治疗鼻炎的胶囊剂药物及制备方法
CN107823453A (zh) 一种治疗耳鸣的新型中药丸及其制备方法
CN106938025A (zh) 一种用于治疗气喘的新型中药组合物及其制备方法
CN105194637A (zh) 一种用于治疗感冒的中药制剂及制备方法
CN106177607A (zh) 一种可有效治疗慢性咽炎的中药组合物
CN104491275A (zh) 一种用于痔疮护理的中药制剂及制备方法
CN107496794A (zh) 一种治疗支气管哮喘的丸剂药物及其制备方法
CN107596163A (zh) 一种用于治疗黑头粉刺的丸剂药物及其制备方法
CN107343937A (zh) 一种治疗气虚咳嗽的胶囊剂药物及制备方法
CN107496877A (zh) 一种用于治疗支气管哮喘的汤剂药物及其制备方法
CN107349367A (zh) 一种治疗哮喘病的新型中药组合物及制备方法
CN110201062A (zh) 一种用于治疗慢性鼻炎的中药组合物及其制备方法
CN108186769A (zh) 一种治疗鼻炎的内服中药丸及制备方法
CN107802784A (zh) 一种用于治疗肺癌的中药组合物及制备方法
CN107823515A (zh) 一种治疗风热感冒的内服药物及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20171222