CN107496827A - 一种可有效治疗子宫肌瘤的丸剂药物及其制备方法 - Google Patents

一种可有效治疗子宫肌瘤的丸剂药物及其制备方法 Download PDF

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CN107496827A
CN107496827A CN201710683997.9A CN201710683997A CN107496827A CN 107496827 A CN107496827 A CN 107496827A CN 201710683997 A CN201710683997 A CN 201710683997A CN 107496827 A CN107496827 A CN 107496827A
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孙素蓉
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Chengdu Fengmi Biotechnology Co Ltd
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Abstract

本发明属于中药制剂领域,目的是根据中医治疗子宫肌瘤的认识机理而提供的一种可有效治疗子宫肌瘤的丸剂药物,所述药物的各个组分及其质量份比如下:鳖甲100~350g、白花蛇舌草500~1100g、水红花子30~120g、仙鹤草60~150g、三棱50~120g、牡丹皮60~150g、半枝莲150~350g、牡蛎150~350g、薏苡仁100~350g、莪术50~100g、三七30~100g、党参60~160g、吴茱萸150~450g;本发明提供的药物是一个很好的中药组方。

Description

一种可有效治疗子宫肌瘤的丸剂药物及其制备方法
技术领域
本发明属于中药制剂领域,具体涉及一种可有效治疗子宫肌瘤的丸剂药物,特别是供子宫肌瘤患者使用的丸剂药物及其制备方法的领域。
背景技术
据文献资料显示:子宫肌瘤是女性生殖器官中最常见的一种良性肿瘤,也是人体中最常见的肿瘤之一,又称为纤维肌瘤、子宫纤维瘤。由于子宫肌瘤主要是由子宫平滑肌细胞增生而成,其中有少量纤维结缔组织作为一种支持组织而存在,故称为子宫平滑肌瘤较为确切。简称子宫肌瘤。
那么,就如何找到一种可效治疗子宫肌瘤的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗子宫肌瘤上,人们逐渐意识到了中医治疗子宫肌瘤的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗子宫肌瘤的现状,本发明的目的是在于提供一种可有效治疗子宫肌瘤的丸剂药物,以解决子宫肌瘤患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述子宫肌瘤。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗子宫肌瘤的丸剂药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲100~350g、白花蛇舌草500~1100g、水红花子30~120g、仙鹤草60~150g、三棱50~120g、牡丹皮60~150g、半枝莲150~350g、牡蛎150~350g、薏苡仁100~350g、莪术50~100g、三七30~100g、党参60~160g、吴茱萸150~450g,辅料:淀粉适量。
一种可有效治疗子宫肌瘤的丸剂药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲115~310g、白花蛇舌草580~950g、水红花子36~105g、仙鹤草68~130g、三棱58~105g、牡丹皮70~130g、半枝莲180~310g、牡蛎180~310g、薏苡仁115~310g、莪术58~90g、三七36~90g、党参70~130g、吴茱萸180~400g,辅助:淀粉适量。
一种可有效治疗子宫肌瘤的丸剂药物及其制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其质量份比如下所示:
鳖甲280g、白花蛇舌草830g、水红花子95g、仙鹤草115g、三棱95g、牡丹皮115g、半枝莲280g、牡蛎280g、薏苡仁280g、莪术80g、三七80g、党参115g、吴茱萸360g,辅料:淀粉适量。
一种可有效治疗子宫肌瘤的丸剂药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除淀粉外,将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物过100目筛后,混合均匀,即得药粉①;其在药粉中加入适量的淀粉,混合均匀,然后制备成丸,即得水丸剂②,③继而干燥、消毒,分装密封即可。
一种可有效治疗子宫肌瘤的丸剂药物及其制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量6g/次,温开水送服(注:月经期暂停服用)。三个月经周期为一疗程,服药1~2个疗程后,瘤体得到控制。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
鳖甲,性味:味咸、性微寒,具有滋阴清热、潜阳熄风、软坚散结之功效,用于治疗阴虚发热、劳热骨蒸、热病伤阴、虚风内动、小作惊痫、久疟、疟母、癥瘕、经闭等症;
白花蛇舌草,性味:苦甘、寒,具有清热、利湿、解毒之功效,用于治疗肺热喘咳、扁桃体炎、咽喉炎、阑尾炎、痢疾、尿路感染、黄疸、肝炎、盆腔炎、附件炎、痈肿疔疮、毒蛇咬伤、肿瘤,亦可用于消化道癌症;
水红花子,性味:咸、性凉,具有活血消积、健脾利湿、清热解毒、明目之功效,用于治疗胁腹癥积、水臌、胃脘痛、食少腹胀、火眼、疮肿、瘰疬等症;
仙鹤草,性味:苦、涩、平,具有收敛止血、截疟、止痢、解毒之功效,用于治疗咳血、吐血、崩漏下血、疟疾、血痢、脱力劳伤、痈肿疮毒、阴痒带下;
三棱,性味:味辛、涩、凉,具有破血行气、消积止痛之功效,用于治疗症瘕痞块、瘀滞经闭、痛经、食积胀痛、跌年伤痛等症;
牡丹皮,性味:苦、辛、微寒,具有清热凉血、活血化瘀之功效,用于治疗温毒发斑、吐血衄血、夜热早凉、无汗骨蒸、经闭痛经、痈肿疮毒、跌扑伤痛;
半枝莲,性味:味辛、苦、性寒,具有清热解毒、散瘀止血、利尿消肿之功效,用于治疗热毒痈肿、咽喉疼痛、肺痈、肠痈、瘰疬、毒蛇咬伤、跌打损伤、吐血、衄血、血淋、水肿、腹水及癌症;
牡蛎,性味:味咸、性微寒,具有平肝潜阳、重镇安神、软坚散结、收敛固涩之功效,用于治疗眩晕耳鸣、惊悸失眠、瘰疬瘿瘤、癥瘕痞块、自汗盗汗、遗精、崩漏、带下等症;
薏苡仁,性味:甘、淡、微寒,具有利湿健脾、舒筋除痹、清热排脓之功效,用于治疗水肿、脚气、小便淋沥、湿温病、泄泻带下、风湿痹痛、筋脉拘挛、肺痈、肠痈、扁平疣等症;
莪术,性味:辛、苦、温,具有破血行气、消积止痛之功效,用于治疗气滞血瘀所致的徵瘕积聚、心腹胀满、气滞食积、闭经痛经、跌打损伤等;
三七,性味:甘、微苦、温,具有散瘀止血、消肿定痛之功效,用于治疗咯血、吐血、衄血、便血、崩漏、外伤出血、胸腹剌痛、跌扑肿痛等症;
党参,性味:味甘、性平,具有健脾补肺、益气生津之功效,用于治疗脾胃虚弱、食少便溏、四肢乏力、肺虚喘咳、气短自汗、气微两亏诸证等症;
吴茱萸,性味:辛、苦、热,有小毒,具有散寒止痛、降逆止呕、助阳止泻之功效,用于治疗厥阴头痛、寒疝腹痛、寒湿脚气、经行腹痛、脘腹胀痛、呕吐吞酸、五更泄泻、外治口疮,高血压。
本发明药物是基于中医治疗子宫肌瘤的原则,从依据子宫肌瘤的病理机制及药理作用认为:就子宫肌瘤,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述子宫肌瘤的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲280g、白花蛇舌草830g、水红花子95g、仙鹤草115g、三棱95g、牡丹皮115g、半枝莲280g、牡蛎280g、薏苡仁280g、莪术80g、三七80g、党参115g、吴茱萸360g,辅料:淀粉适量。
实施例2:
一种可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲310g、白花蛇舌草950g、水红花子105g、仙鹤草130g、三棱105g、牡丹皮130g、半枝莲310g、牡蛎310g、薏苡仁310g、莪术90g、三七90g、党参130g、吴茱萸400g,辅料:淀粉适量。
实施例3:
一种可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲350g、白花蛇舌草1100g、水红花子120g、仙鹤草150g、三棱120g、牡丹皮150g、半枝莲350g、牡蛎350g、薏苡仁350g、莪术100g、三七100g、党参160g、吴茱萸450g,辅料:淀粉适量。
典型病例
经临床诊断治疗子宫肌瘤患者共1290例,年龄为38岁以上的895例,只有395例为38岁以下。1290例患者中瘤体得到控制的690例,有效的529例,无效的71例。总有效率达94.5%。

Claims (3)

1.一种可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲100~350g、白花蛇舌草500~1100g、水红花子30~120g、仙鹤草60~150g、三棱50~120g、牡丹皮60~150g、半枝莲150~350g、牡蛎150~350g、薏苡仁100~350g、莪术50~100g、三七30~100g、党参60~160g、吴茱萸150~450g,辅料:淀粉适量。
2.根据权利要求1所述的可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲115~310g、白花蛇舌草580~950g、水红花子36~105g、仙鹤草68~130g、三棱58~105g、牡丹皮70~130g、半枝莲180~310g、牡蛎180~310g、薏苡仁115~310g、莪术58~90g、三七36~90g、党参70~130g、吴茱萸180~400g,辅料:淀粉适量。
3.根据权利要求1至2所述的可有效治疗子宫肌瘤的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鳖甲280g、白花蛇舌草830g、水红花子95g、仙鹤草115g、三棱95g、牡丹皮115g、半枝莲280g、牡蛎280g、薏苡仁280g、莪术80g、三七80g、党参115g、吴茱萸360g,辅料:淀粉适量。
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