CN107469019A - It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof - Google Patents

It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof Download PDF

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CN107469019A
CN107469019A CN201710922860.4A CN201710922860A CN107469019A CN 107469019 A CN107469019 A CN 107469019A CN 201710922860 A CN201710922860 A CN 201710922860A CN 107469019 A CN107469019 A CN 107469019A
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chinese
medicine composition
root
chinese medicine
fruit
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Sichuan Jintang Haina Biomedical Technology Institute
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of Chinese medicine composition that can effectively treat hepatitis provided according to the traditional Chinese medical science the understanding mechanism of hepatitis, each component and its mass parts ratio of the Chinese medicine composition are as follows：30~120g of the fruit of Chinese magnoliavine, 250~520g of Chinese mahonia, 30~120g of radix bupleuri, 100~220g of the fruit of Chinese wolfberry, 80~160g of root tuber of aromatic turmeric, 80~160g of Radix Angelicae Sinensis, 150~260g of Poria cocos, 50~160g of the red sage root, 30~60g of subprostrate sophora, 30~160g of radix glycyrrhizae, 100~160g of tiger battle, 100~220g of the root of herbaceous peony；Medicine provided by the invention is a Chinese prescription treated both principal and secondary aspect of disease.

Description

It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition that can effectively treat hepatitis, particularly The field of the Chinese medicine composition used for hepatitis and preparation method thereof.
Background technology
Doctor thinks：Hepatitis is the general designation of inflammation.Typically refer to by a variety of pathogenic factors -- such as virus, bacterium, post Infested, chemical toxicant, medicine, alcohol, role of autoimmune factors etc. are destroyed liver cell, and the function of liver suffers damage, Cause a series of malaise symptoms of body, and the exception of liver function index.
Due to triggering the cause of disease of hepatitis different, although there is similar clinical manifestation, in aetology, serology, damage Infringement, diagnosis and treatment etc. often have obvious difference outside mechanism, clinical process and prognosis, liver.
It should be noted that hepatitis described generally in our lives, majority are referred to by the liver such as A type, B-mode, the third type Virus hepatitis caused by scorching virus.
So, a kind of Chinese medicine composition that can effectively treat hepatitis how is just found, is that we are badly in need of being solved at present Problem.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment hepatitis, people gradually appreciate Chinese traditional treatment liver The advantages of scorching, and the advantages such as good effect, toxic side effect be small over the course for the treatment of, for the present situation of existing western medical treatment hepatitis, this The purpose of invention is to be to provide a kind of Chinese medicine composition that can effectively treat hepatitis, is got well early with solving hepatitis The problem of.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and its mass parts ratio, can effectively be treated State hepatitis.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：Hepatitis can effectively be treated by providing one kind Chinese medicine composition and preparation method thereof, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition are as follows It is shown：
30~120g of the fruit of Chinese magnoliavine, 250~520g of Chinese mahonia, 30~120g of radix bupleuri, 100~220g of the fruit of Chinese wolfberry, root tuber of aromatic turmeric 80~ 160g, 80~160g of Radix Angelicae Sinensis, 150~260g of Poria cocos, 50~160g of the red sage root, 30~60g of subprostrate sophora, 30~160g of radix glycyrrhizae, tiger battle 100~160g, 100~220g of the root of herbaceous peony.
It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：
35~105g of the fruit of Chinese magnoliavine, 270~430g of Chinese mahonia, 35~105g of radix bupleuri, 115~200g of the fruit of Chinese wolfberry, root tuber of aromatic turmeric 90~ 140g, 90~140g of Radix Angelicae Sinensis, 170~230g of Poria cocos, 60~140g of the red sage root, 35~50g of subprostrate sophora, 35~140g of radix glycyrrhizae, tiger battle 115~140g, 115~200g of the root of herbaceous peony.
It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof, it is characterised in that " preferred plan " Chinese medicine composition each component and its mass parts than as follows：
Fruit of Chinese magnoliavine 90g, Chinese mahonia 380g, radix bupleuri 90g, fruit of Chinese wolfberry 170g, root tuber of aromatic turmeric 120g, Radix Angelicae Sinensis 120g, Poria cocos 200g, the red sage root 120g, subprostrate sophora 45g, radix glycyrrhizae 120g, tiger battle 120g, root of herbaceous peony 170g.
It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof, it is characterised in that methods described is included such as Lower step is prepared：
A, after above-mentioned raw materials Chinese medicine being picked impurity, dust and dried, it is stand-by to be ground into superfine end according to mass parts ratio；
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing sieving, it is put into medicine device and mixes Mix, be then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, sealed packaging.
It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof, it is characterised in that the instructions of taking is： By the water pill medicine prepared twice a day to take, once a dose sooner or later, and dosage 9g/time（Avoid during medication：Edible oil Greasy, pungent irritable food and tobacco and wine）.One month is a course for the treatment of, and after 2~4 courses for the treatment of of taking medicine, symptom disappears substantially, and disease, which is accused, fullys recover from an illness More.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
The fruit of Chinese magnoliavine, nature and flavor：It is sour, warm-natured, there is the effect of restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, antitoxic heart-soothing and sedative, it is empty for treating cough Asthma, emission, the urine quite disease such as the enuresis, endless diarrhea, spontaneous sweating, injury thirst, palpitation and insomnia；
Chinese mahonia, nature and flavor：It is bitter, cold, leaf：With nourishing Yin and clearing heat, pulmonary tuberculosis, flu are cured mainly；Root, stem：With clearing heat and detoxicating, master Bacillary dysentery, acute smooth gastritis, catarrhal jaundice, pneumonia, pulmonary tuberculosis, bronchitis, abscess of throat are controlled, eye conjunctiva is controlled in external application Inflammation, carbuncle furuncle poison, burn；
Radix bupleuri, nature and flavor：It is bitter, cool, have and inducing diaphoresis in, soothing the liver, rising Yang the effect of, for treating fevers and chills alternate, fullness in the chest and hypochondriac pain, mouth The diseases such as bitter deafness, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis；
The fruit of Chinese wolfberry, nature and flavor：It is sweet, mild-natured, have nourishing the liver, nourshing kidney, moistening lung the effect of, for treat caused by liver and kidney deficiency, have a dizzy spell, Visual one is clear, soreness and weakness of waist and knees, the expensive essence of impotence, cough due to consumptive disease, quenches one's thirst and draws drink；
Root tuber of aromatic turmeric, nature and flavor：It is acrid flavour, hardship, cold in nature, there is the effect of promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, soothing liver-gallbladder, use In all pain for the treatment of chest and abdomen side of body rib, dysmenorrhes, Amenorrhea, abdominal mass caking, pyreticosis coma, demented, frightened epilepsy, haematemesis, nosebleed be standby, blood strangury, Sand leaching, jaundice；
Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type stomachache, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury；
Poria cocos, nature and flavor：It is sweet, light, flat, have eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative the effect of, for treat difficult urination, The diseases such as oedema turgor, phlegm and retained fluid cough are inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea；
The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；
Subprostrate sophora, nature and flavor：It is bitter, cold, it is poisonous, there is the effect of clearing heat and detoxicating, detumescence relieving sore-throat, pented up for treating fiery poison, acute tonsillitis The illnesss such as larynx numbness, abscess of throat, gingivitis, aphthae；
Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；
Tiger battle, nature and flavor：Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；
The root of herbaceous peony, nature and flavor：It is picric acid, cool, have nourishing blood and liver, it is slow in analgesic, hold back cloudy the effect of receiving sweat, for treating chest and abdomen side of body rib pain Bitterly, under diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, band.
Medicine of the present invention is the principle based on Chinese traditional treatment hepatitis, is thought from pharmacological action and mechanism of action：With regard to hepatitis one Demonstrate,prove, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned hepatitis, the medicine prepared using the formula Good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the specific of the present invention Embodiment is described in further detail：
Embodiment 1：
A kind of Chinese medicine composition that can effectively treat hepatitis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：
Fruit of Chinese magnoliavine 90g, Chinese mahonia 380g, radix bupleuri 90g, fruit of Chinese wolfberry 170g, root tuber of aromatic turmeric 120g, Radix Angelicae Sinensis 120g, Poria cocos 200g, the red sage root 120g, subprostrate sophora 45g, radix glycyrrhizae 120g, tiger battle 120g, root of herbaceous peony 170g.
Embodiment 2：
A kind of Chinese medicine composition that can effectively treat hepatitis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：
Fruit of Chinese magnoliavine 105g, Chinese mahonia 430g, radix bupleuri 105g, fruit of Chinese wolfberry 200g, root tuber of aromatic turmeric 140g, Radix Angelicae Sinensis 140g, Poria cocos 230g, pellet Join 140g, subprostrate sophora 50g, radix glycyrrhizae 140g, tiger battle 140g, root of herbaceous peony 200g.
Embodiment 3：
A kind of Chinese medicine composition that can effectively treat hepatitis, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：
Fruit of Chinese magnoliavine 120g, Chinese mahonia 520g, radix bupleuri 120g, fruit of Chinese wolfberry 220g, root tuber of aromatic turmeric 160g, Radix Angelicae Sinensis 160g, Poria cocos 260g, pellet Join 160g, subprostrate sophora 60g, radix glycyrrhizae 160g, tiger battle 160g, root of herbaceous peony 220g.
Model case
Through clinical conditions hepatitis totally 625, the age is 325 of more than 31 years old, and only 300 are less than 31 years old. 600 to be fully recovered in 625 patients, effective 25, total effective rate is up to 100%.

Claims (3)

  1. A kind of 1. Chinese medicine composition that can effectively treat hepatitis, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：
    30~120g of the fruit of Chinese magnoliavine, 250~520g of Chinese mahonia, 30~120g of radix bupleuri, 100~220g of the fruit of Chinese wolfberry, root tuber of aromatic turmeric 80~ 160g, 80~160g of Radix Angelicae Sinensis, 150~260g of Poria cocos, 50~160g of the red sage root, 30~60g of subprostrate sophora, 30~160g of radix glycyrrhizae, tiger battle 100~160g, 100~220g of the root of herbaceous peony.
  2. 2. the Chinese medicine composition according to claim 1 that can effectively treat hepatitis, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：
    35~105g of the fruit of Chinese magnoliavine, 270~430g of Chinese mahonia, 35~105g of radix bupleuri, 115~200g of the fruit of Chinese wolfberry, root tuber of aromatic turmeric 90~ 140g, 90~140g of Radix Angelicae Sinensis, 170~230g of Poria cocos, 60~140g of the red sage root, 35~50g of subprostrate sophora, 35~140g of radix glycyrrhizae, tiger battle 115~140g, 115~200g of the root of herbaceous peony.
  3. 3. the Chinese medicine composition that can effectively treat hepatitis according to claim 1 to 2, it is characterised in that the Chinese medicine group The each component and its mass parts of compound are than as follows：
    Fruit of Chinese magnoliavine 90g, Chinese mahonia 380g, radix bupleuri 90g, fruit of Chinese wolfberry 170g, root tuber of aromatic turmeric 120g, Radix Angelicae Sinensis 120g, Poria cocos 200g, the red sage root 120g, subprostrate sophora 45g, radix glycyrrhizae 120g, tiger battle 120g, root of herbaceous peony 170g.
CN201710922860.4A 2017-09-30 2017-09-30 It is a kind of effectively to treat Chinese medicine composition of hepatitis and preparation method thereof Withdrawn CN107469019A (en)

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