CN107440693A - Physiological detection method and its device - Google Patents

Physiological detection method and its device Download PDF

Info

Publication number
CN107440693A
CN107440693A CN201610373586.5A CN201610373586A CN107440693A CN 107440693 A CN107440693 A CN 107440693A CN 201610373586 A CN201610373586 A CN 201610373586A CN 107440693 A CN107440693 A CN 107440693A
Authority
CN
China
Prior art keywords
physiological
signal
information
digitlization
point
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610373586.5A
Other languages
Chinese (zh)
Inventor
许博钧
庄程钧
张凯彦
郑国宏
杨耀焜
林郁翔
余昭蓉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leadtek Technology Co Ltd
Leadtek Research Inc
Original Assignee
Leadtek Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leadtek Technology Co Ltd filed Critical Leadtek Technology Co Ltd
Priority to CN201610373586.5A priority Critical patent/CN107440693A/en
Publication of CN107440693A publication Critical patent/CN107440693A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0261Measuring blood flow using optical means, e.g. infrared light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • A61B5/02021Determining capillary fragility
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026Measuring blood flow
    • A61B5/0295Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

A kind of physiological detection method and its device.The physiological detection method comprises the following steps:The tested position of human body is detected, to obtain sensing signal.Then, sensing signal is handled, to export digitlization physiological signal.Digitlization physiological signal is received, to calculate first and second information for the characteristic point for obtaining digitlization physiological signal, and the ratio of the second information and the first information is calculated again, to obtain physiological status index.Digitizing physiological signal is included according to multiple pulses caused by sequential, and the characteristic point for digitizing physiological signal includes the wave crest point of pulse and the starting point positioned at the rising edge front end of pulse.

Description

Physiological detection method and its device
Technical field
The present invention relates to a kind of physiological detection method, and more particularly to one kind is used for detecting body processes state Physiological detection method.
Background technology
Angiocardiopathy is as one of underlying cause of death of countries in the world.Therefore, various human body angiocarpy follow The detection mode of ring and its research and development are more generally taken seriously.In current detection mode, with The light Volume Changes that light Volume Changes describer (Photoplethysmography, abbreviation PPG) is sent are retouched State signal and be gradually taken seriously to measure the mode of the peripheral blood circulation of human body.Light Volume Changes describer Extractable blood body measurements light volumetric pulse, and further by arithmetic element according to cutting The light volumetric pulse that takes calculates physiological status index.
Specifically, arithmetic element can be accumulated the letter of the characteristic point of pulse signal by the body of light of body measurements Cease to calculate physiological status index.Fig. 1 is the volumetric pulse of the digitlization physiological signal according to known technology Timing chart.Refer to Fig. 1, it is known that the computing mode of physiological status index be according to pulse Difference in height a between trough point d3 and wave crest point d1 (namely with shrinking wave crest point), and trough point d3 Ratio calculation to the difference in height b between the d2 of diastolic wave summit goes out the elasticity indexes of blood vessel.In addition, , also can be via the height and contraction wave crest point d1 to diastolic wave summit for calculating testee in the computing mode known Hardenability value of the ratio of time difference Td between d2 as blood vessel.
However, there is shortcoming in the computing mode of above-mentioned physiological status index.Specifically, it is normal tested The light volumetric pulse of person has the pulse of of short duration a bounce-back and rising during decline, and it is above-mentioned Diastolic wave.But the testee that physical condition is bad or older, its tested position institute The body of light product pulse signal and the position on the summit without diastolic wave or diastolic wave that detection obtains are failed to understand It is aobvious, and the physiological status index of testee can not be effectively obtained according to above-mentioned computing mode.Therefore, on The detection for the physiological status index stated and computing mode can not be applied to all testees.Also therefore, how The physiological detection method of testing result that is correct and being simply applied to all testees is provided, it has also become The important topic of those skilled in the art.
The content of the invention
The present invention provides a kind of physiological detection method, and it is calculated via the characteristic point of digitlization physiological signal Physiological status index, and the peripheral circulation condition of human body is simply assessed according to physiological status index.
The present invention provides a kind of physiology detection apparatus, and it is detected by way of non-intrusion type and evaluator The peripheral circulation state of body.
The step of physiological status detection method of the present invention, includes:The tested position of human body is detected, to obtain Sensing signal.Then, sensing signal is handled, to export digitlization physiological signal.Receive numeral Change physiological signal, to obtain the first information and the second information of the characteristic point for digitizing physiological signal, and The ratio of the second information and the first information is calculated again, to obtain physiological status index.Digitize physiological signal Including according to multiple pulses caused by sequential, and the characteristic point for digitizing physiological signal includes the wave crest point of pulse And positioned at pulse rising edge front end starting point.
The physiology detection apparatus of the present invention includes sensing unit, signal processing unit and computing module.Sense The tested position that unit is adapted to detect for human body is surveyed, to obtain sensing signal.Signal processing unit receives sensing Signal, and sensing signal is handled, to export digitlization physiological signal.Computing module receives numeral Change physiological signal and obtain the first information and the second information of the characteristic point of digitlization physiological signal.Computing mould The ratio of the information of block computing second and the first information, to obtain physiological status index.Digitize physiological signal With according to multiple pulses caused by sequential, and the characteristic point for digitizing physiological signal includes the crest of pulse Point and the starting point positioned at the rising edge front end of pulse.
In one embodiment of this invention, pulse of the above-mentioned first information between starting point and wave crest point The integral area of relative time axle, and pulse relative time of second information between two adjacent starting points The integral area of axle.
In one embodiment of this invention, time of the above-mentioned first information between starting point and wave crest point Difference, and time difference of second information between two adjacent starting points.
In one embodiment of this invention, above-mentioned processing sensing signal, to export digitlization physiological signal The step of include:Sensing signal is filtered, amplifies sensing signal and sensing signal is converted into number Word physiological signal.
In one embodiment of this invention, the information of above-mentioned calculating characteristic point, to obtain physiological status index The step of include:Normalization digitlization physiological signal and the spy from the digitlization physiological signal after normalization Physiological status index is calculated in the first information of sign point and the second information.
In one embodiment of this invention, above-mentioned sensing unit is light Volume Changes describer.Body of light is accumulated Change describer (Photoplethysmography, abbreviation PPG) includes optical transmitting set and optical receiver. Optical transmitting set emits beam, and the tested position that light passes through human body.Optical receiver is received by being tested portion The light of position, to obtain sensing signal.
In one embodiment of this invention, above-mentioned signal processing unit include wave filter, amplifier and Analog-digital converter.Wave filter is used for being filtered sensing signal.Amplifier is used for amplifying sensing letter Number.Analog-digital converter is then for sensing signal is converted into digitlization physiological signal.
In one embodiment of this invention, above-mentioned computing module includes normalization process unit and physiology State indices arithmetic element.Normalization process unit is used for normalization digitlization physiological signal.Physiological status Exponent arithmetic unit is used for calculating physiological status from the characteristic point of the digitlization physiological signal after normalization Index.
Based on the physiological detection method in above-mentioned, of the invention multiple embodiments examined by detection means The tested position of human body is surveyed, to obtain the sensing signal of the physiological status at tested position.In addition, sensing letter Number it can further be handled via signal processing unit and then export digitlization physiological signal.Furthermore transport Calculating module can be by calculating multiple characteristic points, and according to digitlization physiological signal in digitlization physiological signal The information of characteristic point calculates physiological status index.In embodiments of the invention, the physiology of human body Physiological status index that state can be obtained simply via above-mentioned method and device is assessed, with Reduce time, flow, equipment and the correlative charges needed for physiological detection.
For features described above of the invention and advantage can be become apparent, special embodiment below, and coordinate Accompanying drawing is described in detail below.
Brief description of the drawings
Fig. 1 is the timing chart of the volumetric pulse of the digitlization physiological signal according to known technology.
Fig. 2 is the block schematic diagram of the physiology detection apparatus according to one embodiment of the invention.
Fig. 3 A to Fig. 3 C are the arteries and veins of the volumetric pulse of the digitlization physiological signal of Fig. 2 physiology detection apparatus Rush oscillogram.
Fig. 4 is the schematic flow sheet of the physiological detection method according to one embodiment of the invention.
Fig. 5 is the schematic flow sheet of the signal processing method of Fig. 4 physiological detection method.
Fig. 6 is the schematic flow sheet of the operation method of the physiological status index of Fig. 4 physiological detection method.
【Symbol description】
100:Physiology detection apparatus
110:Sensing unit
112:Optical transmitting set
114:Optical receiver
120:Signal processing unit
122:Wave filter
124:Amplifier
126:Analog-digital converter
130:Computing module
132:Normalization process unit
134:Physiological status exponent arithmetic unit
150:Display unit
160:Transmission unit
170:Memory cell
A1、A2:Integral area
a、b:Difference in height
d1:Wave crest point/contraction wave crest point
d2:Diastolic wave summit
d3、P3:Trough point
P1、P1’:Starting point
P2:Wave crest point
S1:Sensing signal
S2:Digital physiologic signal
Td、T1、T2:Time difference
S201~S203, S301~S303, S401~S403:Step
Embodiment
Multiple embodiments hereafter have the component or dress of same or similar function with identical symbology Put, the shape of element, size, ratio etc. are only to illustrate wherein shown in schema, the non-reality to the present invention Scope is applied to be any limitation as.In addition, though any embodiment described in following description discloses multiple skills simultaneously Art feature, also it is not intended that all technical characteristics in any embodiment must be implemented simultaneously.
Fig. 2 is the block schematic diagram of the physiology detection apparatus according to one embodiment of the invention.Fig. 3 A extremely scheme 3C is the timing chart of the volumetric pulse of the digitlization physiological signal of Fig. 2 physiology detection apparatus.It please join Fig. 2 and Fig. 3 is examined, in the present embodiment, physiology detection apparatus 100 includes sensing unit 110, at signal Manage unit 120 and computing module 130.Sensing unit 110 is, for example, light Volume Changes describer, and And the light of specific wavelength that sensing unit 110 can send and receive by it, its absorbed spectrum The number of energy, to detect and judge the physiological status at the tested position of human body.For example, human body Tested position can be the tip positions such as finger or the toe of human body.In the present embodiment, sensing unit 110 Including one or more groups of optical transmitting set 112 and optical receiver 114, and optical transmitting set 112 and light-receiving The form of device 114 can be penetration or reflective.Therefore, the light that optical transmitting set 112 is sent can After penetrating the tested position of human body or being reflected via tested position, then by corresponding optical receiver 114 Received.
The optical transmitting set 112 and optical receiver 114 of the present embodiment are, for example, the infrared light with specific wavelength Transmitter and infrared light receiver, the scope of the wavelength of its light for sending and receiving are to fall to receive 760 Between rice (nm) and 1 millimeter (mm).However, the present embodiment is not limited thereto, according to physiology detection apparatus The light of 100 detection demand, optical transmitting set 112 and optical receiver 114 is alternatively green glow (wave-length coverage Fall between 495 nanometers and 570 nanometers), feux rouges (wave-length coverage falls between 620 nanometers and 750 nanometers) The either light of other species or wave-length coverage.
Specifically, the sensing unit 110 of physiology detection apparatus 100 can be used to obtain sensing signal S1, And the sensing signal S1 of the present embodiment can be accumulated by the body of light that above-mentioned light Volume Changes describer is sent Signal is described.In the present embodiment, the optical receiver 114 of sensing unit 110 has Photosensing Units (not Illustrate), and Photosensing Units can be used to receive the light for passing through or reflecting the tested position from human body.Therefore, The spectral energy that sensing unit 110 is absorbed by the ferroheme of e.g. blood in the tested position of detection Number calculates the change of the cubical content of the blood in blood vessel.It is noted that in the blood of human body The concentration of ferroheme about can be considered certain, therefore, in typical circumstances, detected in the blood vessel The number of ferroheme can be used to infer the change of the cubical content of the blood in blood vessel, and then obtain above-mentioned Sensing signal S1.
For light when by the blood vessel of human body, the size of absorbed spectral energy can be with heart in light Pulse and produce change.Specifically, the unit area of endovascular tube wall can with heartthrob with And flowing through for blood and cause to expand and shrink.Therefore, by the light of blood vessel can with blood vessel expansion, Shrink and blood vessel in blood perfusion amount size variation and produce class and periodically change, and then produce class Periodic sensing signal S1.
In general, when the heart contraction of human body, blood is driven into arteries, now, With the increase of the volumetric blood amount in blood vessel so that absorbed spectral energy is consequently increased in light, And then produce larger sensing signal S1.Therefore, the tested position of sensing signal S1 size and human body Endovascular volumetric blood amount (perfusion flow) into positive correlation.
Fig. 2 is refer again to, signal processing unit 120 is coupled to sensing unit 110, to receive sensing unit Sensing signal S1 caused by 110.The signal processing unit 120 of the present embodiment include wave filter 122, Amplifier 124 and analog-digital converter 126.In the present embodiment, wave filter 122 can be to receiving The sensing signal S1 that arrives carries out bandpass filtering, and the scope of frequency filtering be fall 0.5 hertz (Hz) with Between 5 hertz.It is appropriate that the filter range of above-mentioned wave filter 122 can be done according to different detection demands Change.
The amplifier 124 of signal processing unit 120 can be by sensing signal S1 automatic gains to appropriate big It is small.In addition, analog-digital converter 126 can by after amplification but still turn for the sensing signal S1 of analog signal Digitlization physiological signal S2 is changed to, in favor of carrying out follow-up signal transacting and related operation.
In the present embodiment, after sensing signal S1 first can amplify via amplifier 124 as described above, then via Analog-digital converter 126 will be that the sensing signal S1 of analog signal is converted to digitlization physiological signal originally S2.Or sensing signal S1 also first can be converted to digitlization physiology letter via analog-digital converter 126 Number S2, then carry out signal amplification via amplifier 124 again.
Computing module 130 is coupled to signal processing unit 120, and computing module 130 can be used to computing Above-mentioned digitlization physiological signal S2, to obtain the information of digitlization physiological signal S2 characteristic point.It please join Fig. 3 A are examined, in the present embodiment, corresponding to the pulsation of heart, blood injects blood vessel by cardiac cycle In, digitlization physiological signal S2 has according to multiple pulses caused by sequential, and the size of pulse is correspondingly entered Enter the volumetric blood amount in blood vessel.As shown in Figure 3A, digitizing physiological signal S2 characteristic point may include Wave crest point P2, trough point P3 in pulse and positioned at pulse rising edge front end starting point P1. In the present embodiment, the starting point P1 reflections of pulse is that the diastole of human body terminates and prepares to start During contraction, the pressure of vascular wall and endovascular volumetric blood.
The wave crest point P2 of pulse be pulse summit, and wave crest point P2 reflected be heart contraction when, Ventricle projects the maximum pulse amplitude caused by the blood into blood vessel.In the present embodiment, starting point When what P1 to wave crest point P2 rising wave band represented is the ventricle fast rapid fire blood of heart, in arteries Volumetric blood amount quickly increases, and makes the state of the tube wall Rapid Expansion of blood vessel.In addition, wave crest point P2 it What rear decline wave band represented is that volumetric blood amount in arteries gradually decreases, and the tube wall of blood vessel The state gradually returned back to before expansion.It is noted that digitlization physiological signal S2 pulse is by originating The size of impulse waveform ascensional range between point P1 to wave crest point P2 can by heart blood output quantity, The influence for penetrating blood speed of the resistance of artery, the tube wall elasticity of blood vessel and ventricle.Furthermore this area skill Art personnel know, when the amplitude that the pulse between starting point P1 to wave crest point P2 rises is bigger, starting point The time difference that P1 reaches wave crest point P2 is shorter, and the perfusion state of the blood in expression blood vessel is better.Also Be, blood vessel can within the more short time Rapid Expansion, that is, represent blood vessel tube wall hardenability it is smaller and elastic Better.
In the present embodiment, computing module 130 includes normalization process unit 132 and physiological status index Arithmetic element 134.After when the computing of computing module 130 and obtaining digitlization physiological signal S2 characteristic point, It is regular that the recycling normalization process unit 132 of computing module 130 manages digital signal S2 progress Change, and the primary signal size for making digitlization physiological signal S2 return back to before amplifying through amplifier 124.Connect , the physiological status exponent arithmetic unit 134 of computing module 130 can be according to digitlization physiological signal S2's The first information of characteristic point and the second information calculate physiological status index.
Specifically, it refer to the horizontal cross shaft of Fig. 3 A and Fig. 3 B, Fig. 3 A and Fig. 3 B pulse pattern For time shaft, its unit is millisecond (ms), and the vertical axes of pulse pattern correspondingly digitize physiological signal The size of S2 volumetric pulse.In the present embodiment, the information of the characteristic point of pulse include the first information and Second information.The first information be pulsion phase in Fig. 3 A between starting point P1 to wave crest point P2 for when The integral area A1 of countershaft, and the second information be Fig. 3 B in two starting points P1, P1 ' between (also A complete heart beat cycle) pulsion phase for time shaft integral area A2.In addition, physiological status Exponent arithmetic unit 134 can calculate the ratio of the second information and the first information, that is, integral area A2 With integral area A1 ratio, to obtain corresponding physiological status index, and blood in blood vessel is assessed according to this The state of liquid perfusion, and the sanguimotor state of body.In addition, in the present embodiment, face The mode that each amplitude commonly used in computer science moves to left can be used to reduce computing in the mode that product calculates Amount.
Fig. 3 C are refer to, in another embodiment, the first information of the characteristic point of pulse is alternatively Fig. 3 C In pulse starting point P1 and wave crest point P2 between time difference T1, and the second information be Fig. 3 C in Adjacent two starting point P1 between time difference T2.The physiological status index fortune of computing module 130 The ratio of above-mentioned second information and the first information can also be calculated by calculating unit 134, that is, time difference T2 timely Between poor T1 ratio, come physiological status index corresponding to obtaining, and assess the blood perfusion in blood vessel according to this State, and the blood circulation function of body.
Compared to the content of Fig. 1 known technologies illustrated, the computing side of the physiological status index of the present embodiment The diastolic wave that formula need not be dependent on the digitlization physiological signal S2 of testee pulse when calculating obtains The second information stated.Particularly, from the numeral measured by testee that is older or being in a bad state of health The pulse for changing physiological signal S2 often lacks diastolic wave, or the vertex position unobvious of diastolic wave, and makes The second information can not effectively be obtained to calculate the second information and the first letter from pulse by obtaining computing module 130 The ratio of breath, and then obtain physiological status index.
Second information of the present embodiment is to be extracted directly from two starting points P1, P1 ' between pulse, also It is directly to extract the second information from the pulse of a complete cycle.Therefore, the physiological status of the present embodiment The computing mode of index is except can be from two starting points P1, P1 ' between pulse intercept the second information in addition to, Can be by the arteries and veins between any characteristic point (being, for example, the trough point in Fig. 3 A) repeated in adjacent pulse Bring the second information of interception.Also therefore, the mode of the present embodiment extraction and the information of computing second is compared known It is more simple for technology, the vertex position without being confined to diastolic wave.
In addition, the content of the known technology compared to Fig. 1, the physiological status index of the present embodiment Computing mode remove according to the time difference T1 between starting point P1 and wave crest point P2 and two starting point P1, Time difference T2 between P1 ' is obtained outside physiological status index to obtain first and second information union, The present embodiment also can according between starting point P1 and wave crest point P2 and two starting points P1, P1 ' between Pulsion phase refers to the integral area of time shaft to obtain first and second information union acquisition physiological status Number.The first information that above two mode obtains and the second information and physiological status index can be compared to each other ginseng Examine, more precisely to judge the circulatory condition of blood in human body.
Table 1
For example, Fig. 3 A to Fig. 3 C are refer to, table 1 is the testee institute for different experiments group Ratio and time difference T2, T1 of the pulsion phase calculated for integral area A2, A1 of time shaft Ratio mean size.In the result of calculation of table 1, group 1 represent be health young man, Group 2 represent be health the elderly, group 3 represent be having diabetes but glycemic control is good Good patient.In general, the blood perfusion state in blood vessel can be with age and caused by disease Artery sclerosis degree increase and gradually fail.It is preferable in healthy situation from the result of table 1 Group in (such as the healthy young man in group 1), the Degree of arteriosclerosis of testee is smaller, above-mentioned The integral area A2/ integral areas A1 of testing result numerical value is larger.It is, two starting point P1, The integration face A2 products of pulse (pulse of namely one complete cycle) relative time axle between P1 ' are relative Pulsion phase between starting point P1 to wave crest point P2 to the integral area A1 of time shaft ratio compared to Other groups are big.Therefore, because the young absent cardiovascular disease again of the testee of group 1 and compare other groups For the testee of group, the state of blood perfusion and circulation in blood vessel is preferable.
In addition, in T1/ time difference, T2 time difference result of calculation, can also reflect healthy situation compared with In good group (group 1 as escribed above), time difference T2/ time difference T1 numerical value is larger, that is, two Individual starting point P1, P1 ' between time difference T2 with respect to the time difference between starting point P1 to wave crest point P2 T1 ratio is big compared to other groups, and it reflects the blood perfusion in the blood vessel of the testee of group 1 And recurrent state is preferable.
In the present embodiment, the user of physiology detection apparatus 100 can be simply via above-mentioned integration face A2, A1 ratio or time difference T2, T1 ratio are accumulated to obtain corresponding physiological status index, according to To assess the situation of the blood perfusion in the blood vessel of human body, and the function of overall body processes system.
Fig. 2 is refer again to, the physiology detection apparatus 100 of the present embodiment includes display unit 150, will be upper The physiological status index stated is shown in display unit 150.In this example it is shown that unit 150 Liquid crystal display or light emitting diode indicator in this way.In addition, physiology detection apparatus 100 may also include Memory cell 170, it is, for example, the various data storage devices such as quick flashing (flash) memory, to store sensing Signal S1 and physiological status index.Furthermore it can be configured in addition in physiology detection apparatus 100 e.g. blue The transmission unit 160 of tooth, WiFi and USB (USB), passes through biography by physiological status index Defeated unit 160, which is sent to smart mobile phone, tablet PC or far-end server etc., can show and record number The device of value, monitored with sharp long-term care.
Fig. 4 is the schematic flow sheet of the physiological detection method of one embodiment of the invention.Refer to Fig. 2 and Fig. 4, the physiological detection method of the present embodiment can substantially divide into following steps:First, it is single using sensing Member 110 detects to the tested position of human body, to obtain sensing signal S1 (step S201).Then, Sensing signal S1 is handled using signal processing unit 120, physiological signal S2 (steps are digitized with output S202).Then, computing module 130 receives digitlization physiological signal S2, to obtain digitlization physiological signal The first information of S2 characteristic point and the second information, and computing module 130 passes through normalization process unit 132 couples of digital reason signal S2 carry out normalization process.Then, computing module 130 is via physiology shape State exponent arithmetic unit 134 is believed to calculate the second information of digitlization physiological signal S2 characteristic point with first The ratio of breath, to obtain physiological status index (step S203).
Fig. 5 is the schematic flow sheet of the signal processing method of Fig. 4 physiological detection method.It refer to Fig. 5 And Fig. 2, furthermore, in the present embodiment, when signal processing unit 120 enters to sensing signal S1 During row signal transacting, signal processing unit 120 can be filtered (step S301) to sensing signal S1, so Processing (step S302) is amplified to sensing signal S1 afterwards.Then, signal processing unit 120 can be by original This is converted to digitlization physiological signal S2 (step S303) for the sensing signal S1 of analog signal.This implementation The sensing signal S1 of example signal amplification procedure and the tandem of Analog-digital Converter step can bases The situation of the actual disposition of signal processing unit 120 and the demand of signal transacting come do appropriate adjustment with Change.
Fig. 6 is the schematic flow sheet of the operation method of the physiological status index of Fig. 4 physiological detection method. Fig. 4, Fig. 2 and Fig. 3 A to Fig. 3 C are refer to, in the present embodiment, above-mentioned physiological status index Calculation procedure may include with the regular digitlization physiology of the normalization process unit 132 of computing module 130 Signal S2 (step S401).Then, computing module 130 can distinguish computing starting point P1 and wave crest point P2 Between pulsion phase starting point P1, P1 adjacent to the integral area of time shaft and two ' between pulsion phase pair The integral area of time shaft, to obtain the first information of digitlization physiological signal S2 characteristic point and the second letter Cease (step S402a).In addition, in another embodiment, computing respectively also may be selected in computing module 130 Time difference and two between starting point P1 and wave crest point P2 adjacent starting point P1, P1 ' between when Between it is poor, to obtain the first information of above-mentioned digitlization physiological signal S2 characteristic point and the second information (step S402b).Then, carry out computing second with the physiological status exponent arithmetic unit 134 of computing module 130 to believe The ratio of breath and the first information, with physiological status index (step 403) corresponding to acquisition.
In summary, the physiological detection method in multiple embodiments of the invention is to utilize physiology detection apparatus Optical transmitting set emit beam, and light can penetrate the tested position of human body or be reflected from tested position The optical receiver of physiology detection apparatus is returned to afterwards, to obtain sensing signal.In addition, sensing signal can pass through The process of signal transacting obtains digitlization physiological signal.The physiological detection method of the present invention can be by numeral The starting point and wave crest point for changing the pulse of physiological signal calculate the pulsion phase of whole cycle for time shaft Integral area and starting point obtain to the pulsion phase between wave crest point for the ratio of the integral area of time shaft Physiological status index corresponding to obtaining.In addition, the physiological detection method of the present invention also can be by adjacent pulse Time difference between two starting points, that is, the time of whole cycle, relative to starting point to wave crest point Between time difference ratio come physiological status index corresponding to obtaining.
In embodiments of the invention, relaxed when the pulse of the digitlization physiological signal of testee is not present Zhang Bo, or diastolic wave summit it is unconspicuous in the case of, the physiological status index of testee still can be via Simple calculations mode and obtain.Furthermore user can simply via above-mentioned physiology detection apparatus and The physiological status index that method obtains assesses the physiological status of human body, and it is, for example, that blood in blood vessel fills Stream and recurrent state.Therefore, flow, time and associated assay devices required during physiological detection And expense can be reduced further.
Although the present invention is disclosed as above with embodiment, so it is not limited to the present invention, this area skill Art personnel without departing from the spirit and scope of the present invention, when can make a little change and retouching, therefore this hair Bright protection domain is worked as to be defined depending on appended claims confining spectrum.

Claims (11)

1. a kind of physiological detection method, its step include:
The tested position of human body is detected, to obtain sensing signal;
The sensing signal is handled, to export digitlization physiological signal;And
The digitlization physiological signal is received, to calculate the multiple features for obtaining the digitlization physiological signal The first information and the second information of point, and the ratio of second information and the first information is calculated again, To obtain physiological status index, wherein digital reason signal is included according to multiple pulses caused by sequential, And the multiple characteristic point includes the wave crest point of each of the multiple pulse and positioned at the multiple arteries and veins The starting point of the front end of the rising edge of each of punching.
2. physiological detection method as claimed in claim 1, wherein the first information is the starting point The pulsion phase between the wave crest point is to the integral area of time shaft, and second information is phase The integral area of the pulsion phase between the two adjacent starting points to the time shaft.
3. physiological detection method as claimed in claim 1, wherein the first information is the starting point With the time difference between the wave crest point, and second information is between the two adjacent starting points Time difference.
4. physiological detection method as claimed in claim 1, wherein the sensing signal is handled, with output The step of digitlization physiological signal, includes:
The sensing signal is filtered;
Amplify the sensing signal;And
The sensing signal is converted into the digitlization physiological signal.
5. physiological detection method as claimed in claim 1, wherein the information of the multiple characteristic point is calculated, Included with obtaining the step of the physiological status index:
The normalization digitlization physiological signal;And
The first information according to the multiple characteristic point of the digitlization physiological signal after normalization And second information calculates the physiological status index.
6. a kind of physiology detection apparatus, including:
Sensing unit, the tested position of human body is adapted to detect for, to obtain sensing signal;
Signal processing unit, the sensing signal is received, and the sensing signal is handled, with Output digitlization physiological signal;And
Computing module, the digitlization physiological signal is received, and calculate and obtain the digitlization physiological signal Multiple characteristic points the first information and the second information, and the computing module calculate second information with The ratio of the first information, to obtain physiological status index, wherein digital reason signal has According to multiple pulses caused by sequential, and the multiple characteristic point includes the ripple of each of the multiple pulse Peak dot and positioned at the multiple pulse the rising edge of each front end starting point.
7. physiology detection apparatus as claimed in claim 6, wherein the first information is the starting point The pulsion phase between the wave crest point is to the integral area of time shaft, and second information is two The integral area of the pulsion phase between the starting point to the time shaft.
8. physiology detection apparatus as claimed in claim 6, wherein the first information is the starting point With the time difference between the wave crest point, and time difference of second information between two starting points.
9. physiology detection apparatus as claimed in claim 6, wherein the sensing unit is light Volume Changes Describer, including:
Optical transmitting set, to emit beam, and the tested position that the light passes through human body;And
Optical receiver, the light by the tested part is received, to obtain the sensing signal.
10. physiology detection apparatus as claimed in claim 6, wherein the signal processing unit includes:
Wave filter, to be filtered to the sensing signal;
Amplifier, to amplify the sensing signal;And
Analog-digital converter, the sensing signal is converted into the digital physiologic signal.
11. physiology detection apparatus as claimed in claim 6, wherein the computing module includes:
Normalization process unit, to the normalization digitlization physiological signal;And
Physiological status exponent arithmetic unit, to from described in the digitlization physiological signal after normalization The information of multiple characteristic points calculates the physiological status index.
CN201610373586.5A 2016-05-30 2016-05-30 Physiological detection method and its device Pending CN107440693A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610373586.5A CN107440693A (en) 2016-05-30 2016-05-30 Physiological detection method and its device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610373586.5A CN107440693A (en) 2016-05-30 2016-05-30 Physiological detection method and its device

Publications (1)

Publication Number Publication Date
CN107440693A true CN107440693A (en) 2017-12-08

Family

ID=60484770

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610373586.5A Pending CN107440693A (en) 2016-05-30 2016-05-30 Physiological detection method and its device

Country Status (1)

Country Link
CN (1) CN107440693A (en)

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05253198A (en) * 1992-03-16 1993-10-05 Matsushita Electric Ind Co Ltd Pulse wave measuring system
CN1114174A (en) * 1994-05-23 1996-01-03 姚雪祥 Automatic analyzing and diagnosing method and apparatus for hemotachogram
US20040158162A1 (en) * 2003-01-24 2004-08-12 Colin Medical Technology Corporation Cuff volumetric pulse wave obtaining apparatus, cuff volumetric pulse wave analyzing apparatus, pressure pulse wave obtaining apparatus, and pressure pulse wave analyzing apparatus
US20060195035A1 (en) * 2005-02-28 2006-08-31 Dehchuan Sun Non-invasive radial artery blood pressure waveform measuring apparatus system and uses thereof
US20080262362A1 (en) * 2007-04-17 2008-10-23 General Electric Company Non-invasive blood pressure determination method
CN101703396A (en) * 2009-11-06 2010-05-12 中国科学院合肥物质科学研究院 Radial artery pulse wave based cardiovascular function parameter detection and analysis method and detection device
CN101785667A (en) * 2010-01-15 2010-07-28 北京工业大学 Waveform characteristic point based method for analyzing volume pulse wave pattern and detection device
CN103330550A (en) * 2013-03-04 2013-10-02 北京中医药大学 Automatic three-portion and nine-pulse-taking information acquisition and recognition device and method of MEMS hydraulic transmission touch
CN103976721A (en) * 2014-04-22 2014-08-13 辛勤 Blood pressure measuring method and embedded device for realizing method
CN104000573A (en) * 2014-05-29 2014-08-27 东北大学 Body surface two point pulse wave based central arterial pulse monitoring system and method
CN104382569A (en) * 2014-12-08 2015-03-04 天津工业大学 Fiber-optic sensing intelligent garment and heart sound and blood pressure parameter processing methods thereof

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05253198A (en) * 1992-03-16 1993-10-05 Matsushita Electric Ind Co Ltd Pulse wave measuring system
CN1114174A (en) * 1994-05-23 1996-01-03 姚雪祥 Automatic analyzing and diagnosing method and apparatus for hemotachogram
US20040158162A1 (en) * 2003-01-24 2004-08-12 Colin Medical Technology Corporation Cuff volumetric pulse wave obtaining apparatus, cuff volumetric pulse wave analyzing apparatus, pressure pulse wave obtaining apparatus, and pressure pulse wave analyzing apparatus
US20060195035A1 (en) * 2005-02-28 2006-08-31 Dehchuan Sun Non-invasive radial artery blood pressure waveform measuring apparatus system and uses thereof
US20080262362A1 (en) * 2007-04-17 2008-10-23 General Electric Company Non-invasive blood pressure determination method
CN101703396A (en) * 2009-11-06 2010-05-12 中国科学院合肥物质科学研究院 Radial artery pulse wave based cardiovascular function parameter detection and analysis method and detection device
CN101785667A (en) * 2010-01-15 2010-07-28 北京工业大学 Waveform characteristic point based method for analyzing volume pulse wave pattern and detection device
CN103330550A (en) * 2013-03-04 2013-10-02 北京中医药大学 Automatic three-portion and nine-pulse-taking information acquisition and recognition device and method of MEMS hydraulic transmission touch
CN103976721A (en) * 2014-04-22 2014-08-13 辛勤 Blood pressure measuring method and embedded device for realizing method
CN104000573A (en) * 2014-05-29 2014-08-27 东北大学 Body surface two point pulse wave based central arterial pulse monitoring system and method
CN104382569A (en) * 2014-12-08 2015-03-04 天津工业大学 Fiber-optic sensing intelligent garment and heart sound and blood pressure parameter processing methods thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘冬岚: "《体检人群中高血压患者的脉图t1_t值分析》", 《中国会议》 *
王超臣: "《高血压患者脉搏波参数与脉搏波传导速度的相关性研究》", 《现代生物医学进展》 *

Similar Documents

Publication Publication Date Title
CN101732040B (en) Non-invasive multipath pulse wave detection device, system and analytical system
CN101327121B (en) Physiological parameter measurement mechanism
WO2017024457A1 (en) Blood-pressure continuous-measurement device, measurement model establishment method, and system
CN110251105A (en) A kind of non-invasive blood pressure measuring method, device, equipment and system
US20150088002A1 (en) Hydration monitoring
TWI610655B (en) A blood pressure monitor coordinated with a cardiovascular health condition monitoring module
JP2006271896A (en) Pulse wave detector, and its detecting method
US20200187835A1 (en) Apparatus and method for estimating blood glucose
US20210369235A1 (en) Method for determining pulse transmission time, arteriosclerosis detection apparatus and system
CN106264504A (en) Noninvasive Blood Pressure Measurement System based on finger arteriogram and method
CN103479343A (en) Central aortic pressure detection system and method based on oscillating sphygmomanometer signals
CN102048526A (en) FPGA (field-programmable gate array)-based cardiovascular parameter non-invasive detection device and control method
CN103284703B (en) Aortic pulse wave transfer time measuring method based on upper extremity artery information
CN107692988A (en) The method of monitoring of blood pressure method and graphic software platform based on intelligent platform
CN104739394A (en) Portable human body physiological signal monitoring and alarming system
CN101371779B (en) Method for extracting traditional Chinese medicine pulse manifestation physiology information
CN105361907A (en) Carotid duplex ultrasound hemodynamic monitor
JP3209577U (en) Physiological detection device
CN104825146A (en) Watch type cacosphyxia alarm
KR102576126B1 (en) Apparatus and method for estimating bio-information
KR20190094725A (en) Dietary habits management apparatus and method
KR102560306B1 (en) Apparatus and method for estimating blood pressure
CN110200599A (en) A kind of pulse wave detecting method, terminal device and system
CN107440693A (en) Physiological detection method and its device
KR20210031281A (en) Apparatus and method for estimating bio-information

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20171208