CN107361730B - A kind of electronic endoscope system - Google Patents

A kind of electronic endoscope system Download PDF

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Publication number
CN107361730B
CN107361730B CN201710678989.5A CN201710678989A CN107361730B CN 107361730 B CN107361730 B CN 107361730B CN 201710678989 A CN201710678989 A CN 201710678989A CN 107361730 B CN107361730 B CN 107361730B
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CN
China
Prior art keywords
light source
accommodation groove
hydraulic cylinder
cold light
electronic endoscope
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CN201710678989.5A
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CN107361730A (en
Inventor
马骁萧
冯宇
付玲
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Huazhong University of Science and Technology
Ezhou Institute of Industrial Technology Huazhong University of Science and Technology
Original Assignee
Huazhong University of Science and Technology
Ezhou Institute of Industrial Technology Huazhong University of Science and Technology
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Application filed by Huazhong University of Science and Technology, Ezhou Institute of Industrial Technology Huazhong University of Science and Technology filed Critical Huazhong University of Science and Technology
Priority to CN201710678989.5A priority Critical patent/CN107361730B/en
Publication of CN107361730A publication Critical patent/CN107361730A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]

Abstract

The invention discloses a kind of electronic endoscope systems, comprising: processing unit is used for circuit control and image procossing;Head, illuminating lens, LED cold light source, object lens and ccd sensor are peeped in endoscope, including column;Connecting conduit, including connection pipe body and connection wiring harness, connection wiring harness is for connecting processing unit and LED cold light source, ccd sensor;Illumination adjustments component, including adjust pedestal, first hydraulic cylinder, second hydraulic cylinder, hydraulic pipe, adjust screw rod and adjusting nut.Illumination adjustments component is arranged to adjust the distance between illuminating lens and LED cold light source in the present invention, so that the dispersion angle that illuminating lens emits beam to LED cold light source is adjusted, and then adjust the ray density of different location on cavity inner wall to be seen, the ray density that cavity inner wall different location to be seen reflexes to ccd sensor is adjusted in it, it can reduce the probability to form shade and speck, more clearly observe image consequently facilitating being formed.

Description

A kind of electronic endoscope system
Technical field
The present invention relates to the field of medical instrument technology, more particularly, to a kind of electronic endoscope system.
Background technique
Medical endoscope as a kind of medical instrument, be widely used in the insertion various cavities of inside of human body clinical observation and It is a kind of important means of disease examination in diagnosis.Common medical endoscope includes hard pipe type endoscope, in optical fiber Sight glass and three kinds of fujinon electronic video endoscope.The working principle of fujinon electronic video endoscope is by the way that pictorial information obtained in object lens to be converted into Electronic information, then by the circuit conversion electronic information, finally show on a display screen.
Currently, illumination for endoscope light source is stabilized light source, i.e. the distance between lighting source and illuminating lens will not It changes, causes illuminating lens not convert the divergence for the illuminating ray that lighting source occurs, due to cavity Inner wall is unavoidably roughness, easily leads to and generates shade on the observation image to be formed, and adjusts brightness and then easily lead to Raised position forms speck, is unfavorable for clinical observation and diagnosis.
Summary of the invention
It is an object of the invention to overcome above-mentioned technical deficiency, a kind of electronic endoscope system is proposed, solve the prior art The technical issues of position solidifies and endoscopic picture is caused to be also easy to produce shade and speck between middle lighting source and illuminating lens.
To reach above-mentioned technical purpose, technical solution of the present invention provides a kind of electronic endoscope system, comprising:
One processing unit is used for circuit control and image procossing;
One endoscope comprising head, illuminating lens, LED cold light source, object lens and ccd sensor are peeped in column;It is peeped in described Head front end is equipped with the first accommodation groove and the second accommodation groove axially arranged along it, and the object lens and illuminating lens are embedded at the respectively The notch of one accommodation groove and the second accommodation groove, the ccd sensor are built in the first accommodation groove, and the LED cold light source sliding connects It is connected to the second accommodating groove sidewall and can be axially moved along the second accommodation groove;
Connecting conduit comprising a connection pipe body and one be built in the connection pipe body connection wiring harness, the connecting line Beam is for connecting the processing unit and LED cold light source, ccd sensor;
Illumination adjustments component comprising adjust pedestal, first hydraulic cylinder, second hydraulic cylinder, hydraulic pipe, adjust screw rod and Adjusting nut;The first hydraulic cylinder is embedded in the second accommodating trench bottom and its tailpiece of the piston rod and the LED cold light source connect Connect, the second hydraulic cylinder be embedded in adjust pedestal adjusting cavity in, the adjusting nut be built in the adjusting cavity and with institute The piston end connection of second hydraulic cylinder is stated, the adjusting screw rod is rotatably connected with adjusting pedestal and one end extends in adjusting cavity And be threadedly coupled with the adjusting nut, the hydraulic pipe be built in connection pipe body and its both ends respectively with first hydraulic cylinder and The cylinder body of second hydraulic cylinder is connected to.
Compared with prior art, illumination adjustments component is arranged to adjust between illuminating lens and LED cold light source in the present invention Distance so that the dispersion angle that illuminating lens emits beam to LED cold light source is adjusted, and then adjusts cavity inner wall to be seen The ray density that cavity inner wall different location to be seen reflexes to ccd sensor is adjusted in the ray density of upper different location, It can reduce the probability to form shade and speck, more clearly observe image consequently facilitating being formed.
Detailed description of the invention
Fig. 1 is the attachment structure schematic diagram of electronic endoscope system of the invention;
Fig. 2 is the structural schematic diagram of endoscope of the invention;
Fig. 3 is the A-A direction view of Fig. 2 of the invention;
Fig. 4 is the structural schematic diagram of illumination adjustments component and image adjustment component of the invention;
Fig. 5 is the structural schematic diagram of U-bracket of the invention;
Fig. 6 is the left view of Fig. 5 of the invention.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and It is not used in the restriction present invention.
Fig. 1~6 are please referred to, the present invention provides a kind of electronic endoscope systems, including processing unit 1, endoscope 2, company Connect conduit 3, illumination adjustments component 4 and image adjustment component 5.Processing unit 1 is generally by conventional circuit control unit and image Processing unit 1 is constituted, and circuit control unit can be used for controlling photo and the operation of other interlock circuits of endoscope 2, image procossing Unit 1 is mainly used for image and its processing for the cavity to be seen for showing that endoscope 2 acquires, and is all made of existing usual manner Processing.
As shown in Figure 1, Figure 2, Figure 3 shows, endoscope 2 includes peeping first 21, illuminating lens 22, LED cold light source 23, object lens in column 24 and ccd sensor 25;First 21 front end is peeped in described is equipped with the first accommodation groove 211 and the second accommodation groove axially arranged along it 212, the object lens 24 and illuminating lens 22 are embedded at the notch of the first accommodation groove 211 and the second accommodation groove 212 respectively, described Ccd sensor 25 is built in the first accommodation groove 211, and the LED cold light source 23 is slidably connected to 212 side wall of the second accommodation groove And it can be axially moved along the second accommodation groove 212;Wherein, the first accommodation groove 211 and the second accommodation groove 212 are all made of circular trough, Illuminating lens 22 and object lens 24 are tightly connected with the notch of the first accommodation groove 211 and the second accommodation groove 212 respectively, and in order to obtain More preferably illuminating effect and image effect, illuminating lens 22 and object lens 24, which can slightly protrude from the first accommodation groove 211 and second, to be held Set slot 212.
For the ease of the adjusting of illuminating ray, the second accommodation groove of the present embodiment 212 may be configured as two, certainly can also basis Needing to be set as three or more, and for the ease of the cooperation of image and illuminating ray, the first accommodation groove 211 can be peeped with interior It is first 21 coaxial arrangement, and two the second accommodation grooves 212 then relatively in peep first 21 central axes be symmetrical arranged.
When practical application, the intracorporal blood stains of chamber to be seen and other liquid easily lead to illuminating lens 22 and the pollution of object lens 24, Therefore first 21 front end can be peeped inside, one antifouling mirror 26 is set, antifouling 26 outer fringe seal of mirror be connected in peep first 21 front outer, by First 21 front end surface is peeped in illuminating lens 22 and object lens 24 protrude from, therefore antifouling mirror 26 may be configured as spherical, i.e., it is antifouling The cross section setting of mirror 26 is arc-shaped.
As shown in Figure 1, connecting conduit 3 includes that a connection pipe body 31 and one are built in the connection wiring harness of the connection pipe body 31 32, for connection wiring harness 32 for connecting processing unit 1 and LED cold light source 23, ccd sensor 25, i.e. processing unit 1 can pass through connection Harness 32 provides electric energy or light energy source to LED cold light source 23, and ccd sensor 25 by the light converted electrical number of reflection and can pass It send to processing unit 1, and the image that can be shown is formed by 1 processing of processing unit, be this field routine techniques, therefore this implementation Example is not described in detail.
As shown in Figure 2, Figure 4 shows, illumination adjustments component 4 include adjust pedestal 41, first hydraulic cylinder 42, second hydraulic cylinder 43, Hydraulic pipe 44 adjusts screw rod 45 and adjusting nut 46;The first hydraulic cylinder 42 is embedded in 212 bottom of the second accommodation groove And its tailpiece of the piston rod is connect with the LED cold light source 23, the second hydraulic cylinder 43 is embedded in the adjusting cavity 411 for adjusting pedestal 41 Interior, the adjusting nut 46 is built in the adjusting cavity 411 and connect with the piston end of the second hydraulic cylinder 43, the adjusting Screw rod 45 and adjusting pedestal 41 are rotatably connected and one end extends in adjusting cavity 411 and connects with 46 screw thread of adjusting nut It connects, the hydraulic pipe 44 is built in connection pipe body 31 and its both ends cylinder with first hydraulic cylinder 42 and second hydraulic cylinder 43 respectively Body connection.When specific setting, since the second accommodation groove 212 is set as two, then first hydraulic cylinder 42, second hydraulic cylinder 43, liquid Pressing conduit 44, adjusting screw rod 45 and adjusting nut 46 is two, and is arranged in a one-to-one correspondence with the second accommodation groove 212.Wherein, One hydraulic cylinder 42 and the second accommodation groove 212 are coaxially disposed, axial along the second accommodation groove 212 convenient for the piston rod of first hydraulic cylinder 42 It moves and LED cold light source 23 is driven to be axially moved along the second accommodation groove 212;And second hydraulic cylinder 43 is set with the dislocation of screw rod 45 is adjusted It sets, and the piston rod of second hydraulic cylinder 43, along the axial setting for adjusting screw rod 45, the piston end of second hydraulic cylinder 43 can adjusted It is axially moved under the action of adjusting nut 46 along adjusting screw rod 45 when screw rod 45 rotates;And hydraulic pipe 44 is then connected to the first liquid Cylinder pressure 42 and second hydraulic cylinder 43, when adjusting screw rod rotates forward, adjusting nut 46 drives the piston end of second hydraulic cylinder 43 It moving upwards, forms negative pressure in second hydraulic cylinder 43, then hydraulic oil enters second hydraulic cylinder 43 by first hydraulic cylinder 42, then and first Negative pressure is formed in hydraulic cylinder 42, the tailpiece of the piston rod of first hydraulic cylinder 42 is moved to far from 22 direction of illuminating lens, can drive LED Far from illuminating lens 22, and when adjusting screw rod 45 rotates backward, the piston end of second hydraulic cylinder 43 moves downward cold light source 23, Then the piston end of corresponding first hydraulic cylinder 42 is moved to the direction close to illuminating lens 22, and LED cold light source 23 can be driven to lean on Near lightning lens 22, can by adjust screw rod 45 rotation adjust control LED cold light source 23 and illuminating lens 22 between away from From, and by adjusting being threadedly engaged between screw rod 45 and adjusting nut 46, it can guarantee the precision adjusted.
In practical application, in order to guarantee to adjust the precision controlled, illumination adjustments component 4 further includes one described for driving The stepper motor 47 and one that adjusting screw rod 45 rotates are used to that stepper motor 47 to be driven to rotate the impulse generator 48 for setting fixing turn, It can be controlled by impulse generator 48 and issue the circle number that the quantity control stepper motor 47 of pulse rotates, and then control to adjust nut 46 distances to move up and down can guarantee the precision of control to control the distance that LED cold light source 23 moves.
The present embodiment illumination adjustments component 4 further includes a guide cylinder 49 mutually agreed with 212 inner wall of the second accommodation groove, The guide cylinder 49 is connect with 212 side walls of the second accommodation groove, and the LED cold light source 23 is built in guide cylinder 49, is led to Crossing one guide cylinder 49 of setting can guarantee that LED cold light source 23 is axially moved along the second accommodation groove 212, avoid it that radial wobble occurs, It ensure that the accuracy that light is adjusted.Meanwhile 212 side wall of the second accommodation groove is provided at least one guide groove axially arranged along it 212a, the conducting bar 491 agreed with guide groove 212a phase is arranged in 49 outer surface of guide cylinder, specifically when setting, guide groove 212a and conducting bar 491 Two are disposed as, opposite second accommodation groove 212 of guide cylinder 49 is can avoid and circumferential movement occurs, advantageously ensure that LED is cold The stability that light source 23 moves.
As shown in figure 2, figure 5 and figure 6, and in order to guarantee the piston rod of first hydraulic cylinder 42 with guide cylinder 49 it moves coaxial Property, a settable U-bracket 40, the U-bracket 40 includes a connection piece 401 and prolongs from 401 free end of connector to one side Two supporting elements 402 to be formed are stretched, the free end of the supporting element 402 is connected to the outer rim of guide cylinder 49, first hydraulic cylinder 42 Piston rod is connected to the middle part of the connector 401, and the length of connector 401 is settable with 212 internal diameter phase of the second accommodation groove Together, opposite second accommodation groove, the 212 inner wall side of corresponding supporting element 402 is set as mutually agreeing with 212 inner wall of the second accommodation groove Arc advantageously ensures that U-bracket 40 is axially moved along the second accommodation groove 212, guarantees the precision that guide cylinder 49 is axially moved.
Image adjustment component 5, it is essentially identical with the control principle of illumination adjustments component 4, it is mainly used for described in adjusting The distance between ccd sensor 25 and object lens 24 are conducive to focus.Since the inner wall of cavity to be seen is sensed with respect to CCD Device 25 is inclined, and it is unintelligible to easily lead to portion, although focus adjustment can be realized by Automatic zoom lens focusing device, It can not clearly observe part, therefore image adjustment component 5 is arranged in the present embodiment, can be by adjusting ccd sensor 25 The distance between object lens 24 automatically adjust focal length, in order to clearly be observed each position in cavity to be seen, benefit In raising subsequent procedures quality.
Compared with prior art, the present invention illumination adjustments component 4 is set with adjust illuminating lens 22 and LED cold light source 23 it Between distance so that the dispersion angle that illuminating lens 22 emits beam to LED cold light source 23 is adjusted, and then adjust to be seen The ray density of different location on cavity inner wall, can reduce the probability to form shade and speck, consequently facilitating being formed more clear The observation image of Chu.
The above described specific embodiments of the present invention are not intended to limit the scope of the present invention..Any basis Any other various changes and modifications that technical concept of the invention is made should be included in the guarantor of the claims in the present invention It protects in range.

Claims (8)

1. a kind of electronic endoscope system characterized by comprising
One processing unit is used for circuit control and image procossing;
One endoscope comprising head, illuminating lens, LED cold light source, object lens and ccd sensor are peeped in column;Before peeping head in described End is equipped with the first accommodation groove and the second accommodation groove axially arranged along it, and the object lens and illuminating lens are embedded at the first appearance respectively The notch of slot and the second accommodation groove is set, the ccd sensor is built in the first accommodation groove, and the LED cold light source is slidably connected to The second accommodating groove sidewall can be simultaneously axially moved along the second accommodation groove;
Connecting conduit comprising a connection pipe body and one be built in the connection pipe body connection wiring harness, the connection wiring harness uses In the connection processing unit and LED cold light source, ccd sensor;
Illumination adjustments component comprising adjust pedestal, first hydraulic cylinder, second hydraulic cylinder, hydraulic pipe, adjust screw rod and adjusting Nut;The first hydraulic cylinder is embedded in the second accommodating trench bottom and its tailpiece of the piston rod is connect with the LED cold light source, institute It states second hydraulic cylinder to be embedded in the adjusting cavity for adjusting pedestal, the adjusting nut is built in the adjusting cavity and with described second The piston end of hydraulic cylinder connects, the adjustings screw rod and adjust pedestal be rotatably connected and one end extend to adjusting cavity it is interior and with institute State adjusting nut threaded connection, the hydraulic pipe be built in connection pipe body and its both ends respectively with first hydraulic cylinder and the second liquid The cylinder body of cylinder pressure is connected to.
2. electronic endoscope system according to claim 1, which is characterized in that the illumination adjustments component further includes a use In the stepper motor for driving the adjusting screw rod rotation and one for driving stepper motor rotation to set the impulse generator of fixing turn.
3. electronic endoscope system according to claim 2, which is characterized in that the illumination adjustments component further include one with The guide cylinder that the second accommodation groove inner wall mutually agrees with, the guide cylinder is connect with the second accommodation groove side walls, described LED cold light source is built in guide cylinder.
4. electronic endoscope system according to claim 3, which is characterized in that it is described second accommodating groove sidewall be provided with to The conducting bar mutually agreed with guide groove is arranged in a few guide groove axially arranged along it, the guide cylinder outer surface.
5. electronic endoscope system according to any one of claims 1 to 4, which is characterized in that first accommodation groove and institute Head coaxial arrangement is peeped in stating, second accommodation groove is two and the relatively described interior central axes of peeping are symmetrical arranged.
6. electronic endoscope system according to claim 5, which is characterized in that the endoscope further includes one set on described The antifouling mirror of a front end is inside peeped, the antifouling mirror outer fringe seal is connected in described and peeps a front outer.
7. electronic endoscope system according to claim 6, which is characterized in that the antifouling mirror cross section is arc-shaped.
8. electronic endoscope system according to claim 7, which is characterized in that the electronic endoscope system further includes one For adjusting the image adjustment component of the distance between the ccd sensor and object lens.
CN201710678989.5A 2017-08-10 2017-08-10 A kind of electronic endoscope system Active CN107361730B (en)

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CN107361730B true CN107361730B (en) 2019-04-16

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110584677A (en) * 2019-07-05 2019-12-20 浙江荷清柔性电子技术有限公司 Signal measuring device, blood oxygen monitoring system and method
CN111297309B (en) * 2020-03-07 2024-01-30 陕西艾诺美瑞申医疗科技有限公司 Electronic endoscope for medical imaging
CN113229771A (en) * 2021-04-23 2021-08-10 苏州法兰克曼医疗器械有限公司 Endoscope with adjustable and controllable illumination function
CN115191911B (en) * 2022-09-16 2022-12-16 苏州科灵医疗科技有限公司 Endoscope capable of intelligently regulating imaging effect

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1759803A (en) * 2004-10-12 2006-04-19 株式会社茉莉特斯 Illumination apparatus and an endoscope with object illumination using the same

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4406130B2 (en) * 1999-10-26 2010-01-27 Hoya株式会社 Optical cable for illumination used in electronic endoscope system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1759803A (en) * 2004-10-12 2006-04-19 株式会社茉莉特斯 Illumination apparatus and an endoscope with object illumination using the same

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