CN107340151A - Fecal sample quantitative collection device and acquisition method - Google Patents
Fecal sample quantitative collection device and acquisition method Download PDFInfo
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- CN107340151A CN107340151A CN201710754181.0A CN201710754181A CN107340151A CN 107340151 A CN107340151 A CN 107340151A CN 201710754181 A CN201710754181 A CN 201710754181A CN 107340151 A CN107340151 A CN 107340151A
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- 230000002550 fecal effect Effects 0.000 title claims description 68
- 238000000034 method Methods 0.000 title claims description 14
- 239000007788 liquid Substances 0.000 claims description 32
- 238000001914 filtration Methods 0.000 claims description 15
- 238000007789 sealing Methods 0.000 claims description 13
- 238000003756 stirring Methods 0.000 claims description 11
- 238000001514 detection method Methods 0.000 claims description 9
- 239000006166 lysate Substances 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 6
- 238000003780 insertion Methods 0.000 claims description 3
- 230000037431 insertion Effects 0.000 claims description 3
- 210000003462 vein Anatomy 0.000 claims description 3
- 230000005611 electricity Effects 0.000 claims description 2
- 238000005259 measurement Methods 0.000 claims description 2
- 238000005070 sampling Methods 0.000 description 6
- 230000032258 transport Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 5
- 230000007547 defect Effects 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000007599 discharging Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 239000008155 medical solution Substances 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000011982 device technology Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
- G01N2001/386—Other diluting or mixing processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Disclose a kind of fecal sample quantitative collection device and acquisition method, fecal sample quantitative collection device includes collection tube (1), gather pipe cap (2) and quantitative collector (6), the collection pipe cap (2) includes being used for the pipe cap end and pipe cap top for connecting the collection tube (1), the pipe cap end is provided with the middle internal thread (12) for being threadedly coupled first externally threaded first internal thread (11) and Second bobbin diameter, the end through hole (13) and liquid feed valve (14) of the 3rd diameter are provided with the top of the pipe cap, the end through hole (13) and middle internal thread (12), first internal thread (11) is sequentially communicated；Described is more than the 3rd diameter greater diameter than Second bobbin diameter, the Second bobbin diameter；When reducing push rod (5) filters fecal sample via filter screen (17) and is pushed to blind end (9), processor (8) controls the mixing speed of agitating unit (10) and the liquid inlet volume of the concentration signal control liquid feed valve (14) based on concentration sensor (7) detection.
Description
Technical field
The present invention relates to medical experiment detection device technology field, particularly a kind of fecal sample quantitative collection device and adopt
Diversity method.
Background technology
The detection of excrement has special meaning to diagnosing some diseases, but conventional use of sample-collecting box is very simple and crude, no
It is easy to the retention of excrement sample, detection also needs the direct operating of contacts of hand when sampling, so as to not only cause person under inspection and tester's inconvenience, and
And smell because of excrement sample or the pathogen that contains and easily form pollution sources, reviewer need to endure sample stink, and excrement
Sample can not quantify, and be not suitable for quantitative testing.There is the defects of following in conventional sampler, it is impossible to meet the need of clinical practice
Will：(1) handshake part of traditional sampler is short and thick, grip inconvenience, and easily makes both hands dirty；(2) legacy sampler is more
Sampled using small spoon structure, it is necessary to the excrement quantity that collection can be only achieved sampling request be repeated several times, operating process is complicated, easily
User is set to produce psychological pressure；(3) excrement of legacy sampler collection is not readily separated, and can not fully be reacted with lysate, unfavorable
In the progress of scientific research personnel's follow-up work；(4) legacy sampler uses the assembling and fixation of single screw thread or buckle, no
It can effectively prevent lysate is mixed to spill and pollute with excrement；(5) legacy sampler uses cheap transparent plastic system mostly
Make, stress is broken, and easily brings psychological pressure to user when in use；(6) legacy sampler is not equipped with defecate collection box,
Stool and urine separation can not be realized and pollute excrement, serious inconvenience is brought to feces collection work；(7) tradition sampling is random, it is impossible to
Ensure collection capacity, cause too much or very little.
Patent document 1 discloses a kind of stool collection cup, including cup, the top cover located at cup top and through top
The sample spoon stretched into cup is covered, a dividing plate is provided with the cup, both sides and the cup inwall linear contact lay of the dividing plate are described
The lower end of dividing plate is provided with filter screen；The inner chamber of cup is isolated stir chamber and test chamber by the filter screen and dividing plate, on the top cover
Instrument connection is provided with test chamber corresponding position.The patent has gathered sample and has been diluted, mixes, filters, and admixing medical solutions are only logical
The filter screen for crossing bottom enters test chamber, therefore admixing medical solutions are than more uniform, but the patent can not quantitative collection sample, decoction and sample
Originally it can not automatically and accurately match and be not suitable for storage and transport, can not facilitate and wholesomely sample, security reliability is poor
And easy secondary pollution.
Patent document 2 discloses that one kind adopts closet, include sample-storing bottle, bottom, protecgulum, blanking cover, one end set of sample-storing bottle
Equipped with U-shaped sealing shroud, adopting the just bottom of rod insertion U-shaped sealing shroud and extending in sample-storing bottle, bottom in bottom, with helicla flute
Outer wall be connected with the end of sample-storing bottle, bottom carries the protecgulum of discharging tube, sets sealing ring, the outer wall of protecgulum in its bottom
It is connected with the other end of sample-storing bottle, the outlet of discharging tube is through hole, and discharging tube is externally connected with blanking cover, blanking cover bottom and discharge opeing
Pipe is provided with sealing gasket between outlet.The setting of the helicla flute and U-shaped sealing shroud of the patent acquisition rod so that each inspected excrement
It is small to measure amplitude of variation, but the patent can only fix the collection of scheduled volume, can not accomplish the quantitative collection of a variety of scheduled volumes, more can not
So that decoction and sample automatically and accurately match and are not suitable for storage and transport.
Patent document 3 discloses that a kind of excrement quantitative collection bottle, including bottle cap set (1), serum cap (2), transparent plastic bottle
Body (3) and bottle holder (4), four symmetrical pipes (5) being provided with serum cap (2), pipe (5) hypomere wall is provided with groove (6),
Pillar (7) is provided with pipe (5), pillar (7) hypomere is provided with bulge loop (8), and pillar (7) upper end is provided with pressing plate (9), and four symmetrical
Pipe (5) lower end outside edge is provided with a circular neck (10), and discoid raised (11), disk are provided with circular neck (10)
Shape projection (11) is provided with the diminishing sleeve pipe of caliber size (12), and serum cap (2) center is communicated with cavity (13), connection
Cavity (13) hypomere is provided with threaded connection (14), and threaded connection (14) is provided with hollow circular tube (15), hollow circular tube (15) hypomere
Provided with cylindrical acquisition cavity (16), piston sheet (17) is provided with cylindrical acquisition cavity (16), piston sheet (17) is provided with piston rod
(18), piston rod (18) passes hollow circular tube (15), and piston rod (18) epimere is provided with neck (19), and connection cavity (13) edge is set
Elastic registration arm (20), transparent plastic body (3) are provided with scale (21), and serum cap (2) edge is provided with water filling port (22), note
The mouth of a river (22) is provided with elastic sealing film (23), and transparent plastic body (3) hypomere is provided with funnel (24), and funnel (24) root is provided with
Filter screen (25), funnel (24) hypomere are provided with delivery port (26).Patent environmental pollution when carrying out just sample inspection is small, operation side
Just it is hygienic, and can quantitative collection excrement, but the patent can not decoction and sample automatically and accurately match and be not suitable for protecting
Deposit and transport, sampling operation is complicated, poor reliability.
Prior art literature
Patent document
Patent document 1：Chinese patent discloses No. CN204214676U
Patent document 2：Chinese patent discloses No. CN2493921A
Patent document 3：Chinese patent discloses No. CN203191221U
The content of the invention
Problems to be solved by the invention
A kind of as described above, the defects of present invention is directed to above-mentioned prior art, there is provided portable fecal sample quantitative collection
Device.The fecal sample quantitative collection device is easy to use, can carry out quantitative collection to stool sample, and decoction and sample are automatic
And match exactly, suitable storage and transport are easy to use and hygienic, can avoid causing secondary pollution.
Solution to problem
The present inventor etc. have made intensive studies to reach above-mentioned purpose, and specifically, the present invention provides a kind of excrement
Just sample quantitative collection device, fecal sample quantitative collection device include collection tube, collection pipe cap and quantitative collector.
The collection tube includes being used for the concentration sensor, processor, blind end and open end for detecting excrement model concentration,
The openend is provided with the first external screw thread of the first diameter, and the blind end is provided with agitating unit.
The collection pipe cap includes being used for the pipe cap end and pipe cap top for connecting the collection tube, and the pipe cap end is set
There is the middle internal thread for being threadedly coupled first externally threaded first internal thread and Second bobbin diameter, be provided with the top of the pipe cap
The end through hole and liquid feed valve of 3rd diameter, the end through hole and middle internal thread, the first internal thread are sequentially communicated.
The quantitative collector includes the interior pipe portion with bigger diameter end and miner diameter end, is movably disposed at said inner tube portion
Reducing push rod and be arranged in the filter screen of interior pipe portion bigger diameter end, the miner diameter end in said inner tube portion is provided with the threaded connection centre
Second external screw thread of internal thread, reducing push rod include the large-diameter portion and minor diameter part for being respectively received in the bigger diameter end and miner diameter end,
The minor diameter part is slidably connected the end through hole, and the large-diameter portion is in close contact the bigger diameter end and wherein slidably,
Described is more than the 3rd diameter greater diameter than Second bobbin diameter, the Second bobbin diameter.
When excrement via strainer filtering and is pushed to blind end by reducing push rod, processor controls agitating unit mixing speed
And the liquid inlet volume of the concentration signal control liquid feed valve based on concentration sensor detection.
The air pressure valve that includes being used in described fecal sample quantitative collection device, at the top of the pipe cap adjusting air pressure and
The pressure sensor of pressure signal in collection tube is measured, the processor for connecting the pressure sensor and air pressure valve is believed based on pressure
Number control pressure valve.
In described fecal sample quantitative collection device, the harvester includes being used for the collection support for holding excrement
Disk, the collection pallet upper end side are outward extended with the Handheld Division of triangle.
In described fecal sample quantitative collection device, the liquid feed valve connection feed tube reaches closing to convey liquid
End, the periphery of agitating unit are provided with the filtering container for being used to filtering out fecal sample after stirring, and the filtering container allows to be less than pre-
The fecal sample for determining threshold size is leached into blind end from the inside of filtering container.
In described fecal sample quantitative collection device, collection tube, collection pipe cap and/or quantitative collector are PVC materials
Material is made.
In described fecal sample quantitative collection device, the bigger diameter end in said inner tube portion and/or the path of reducing push rod
Portion is provided with scale.
It is close that first is provided with described fecal sample quantitative collection device, between the collection tube and the collection pipe cap
Seal, the second sealing ring is provided between said inner tube portion and the collection pipe cap.
In described fecal sample quantitative collection device, the reducing push rod is piston push rod, wherein, large-diameter portion is work
Chock plug.
In described fecal sample quantitative collection device, the periphery of the collection pipe cap is provided with anti-slip veins, described small
Footpath portion top is provided with handle, the lysate of the liquid feed valve input scheduled volume.
In described fecal sample quantitative collection device, the processor be general processor, digital signal processor,
Application-specific integrated circuit ASIC, on-site programmable gate array FPGA, analog circuit or digital circuit, the processor include storage
Device, the memory can including one or more read only memory ROMs, random access memory ram, flash memory or electronics
Erasable programmable read-only memory (EPROM) EEPROM.
According to another aspect of the present invention, the step of the acquisition method of the fecal sample quantitative collection device described in a kind of utilization
Suddenly include:
In quantitative collector insertion excrement, the relatively interior pipe portion of reducing push rod is moved up to aspirate the excrement of scheduled volume to greatly
Footpath end.
Quantitative collector is put into collection tube, and the first internal thread is threadedly coupled first external screw thread, the middle internal thread
The second external screw thread is threadedly coupled, the collection pipe cap connects the quantitative collector and collection tube.
Excrement via strainer filtering and is pushed to blind end by reducing push rod, and processor controls agitating unit with predetermined stirring
Speed stirs fecal sample, and the liquid inlet volume of the concentration signal control liquid feed valve based on concentration sensor detection.
Described above is only the general introduction of technical solution of the present invention, in order to cause the technological means of the present invention clearer
Understand, reach the degree that those skilled in the art can be practiced according to the content of specification, and in order to allow the present invention
Above and other objects, features and advantages can become apparent, below with the present invention embodiment illustrated
Explanation.
Brief description of the drawings
[Fig. 1] shows the structural representation of the fecal sample quantitative collection device of one embodiment of the invention.
[Fig. 2] shows the structural representation of the fecal sample quantitative collection device of another embodiment of the present invention.
[Fig. 3] show one embodiment of the invention using fecal sample quantitative collection device acquisition method the step of
Schematic diagram.
Symbol description
1 collection tube
2 collection pipe caps
Pipe portion in 3
4 reducing push rods
5 collection pallets
6 quantitative collectors
7 concentration sensors
8 processors
9 blind ends
10 openends
11 first internal threads
12 middle internal threads
13 end through holes
14 liquid feed valves
15 miner diameter ends
16 bigger diameter ends
17 filter screens
18 large-diameter portions
19 minor diameter parts
20 air pressure valves
21 pressure sensors
22 feed tubes
23 filtering containers
Embodiment
The specific embodiment of the present invention is more fully described below with reference to accompanying drawings.Although show the present invention's in accompanying drawing
Specific embodiment, it being understood, however, that may be realized in various forms the present invention without should be limited by embodiments set forth here
System.Conversely, there is provided these embodiments are to be able to be best understood from the present invention, and can be complete by the scope of the present invention
Be communicated to those skilled in the art.
It should be noted that some vocabulary has been used to censure specific components among specification and claim.Ability
Field technique personnel it would be appreciated that, technical staff may call same component with different nouns.This specification and right
It is required that not in a manner of the difference of noun is used as and distinguishes component, but differentiation is used as with the difference of component functionally
Criterion."comprising" or " comprising " as mentioned in working as in specification in the whole text and claim are an open language, therefore should be solved
It is interpreted into " include but be not limited to ".Specification subsequent descriptions for implement the present invention better embodiment, so it is described description be with
For the purpose of the rule of specification, the scope of the present invention is not limited to.Protection scope of the present invention is when regarding appended right
It is required that institute's defender is defined.
For ease of the understanding to the embodiment of the present invention, done further by taking several specific embodiments as an example below in conjunction with accompanying drawing
Explanation, and each accompanying drawing does not form the restriction to the embodiment of the present invention.
Specifically, a kind of fecal sample quantitative collection device as shown in Figure 1.Fecal sample quantitative collection device includes adopting
Collector 1, collection pipe cap 2 and quantitative collector 6.
The collection tube 1 is including the concentration sensor 7 for detecting fecal sample concentration, processor 8, blind end 9 and opens
Mouth end 10, the openend 10 are provided with the first external screw thread of the first diameter, and the blind end 9 is provided with agitating unit 10.
The collection pipe cap 2 includes being used for the pipe cap end and pipe cap top for connecting the collection tube 1, the pipe cap end
Provided with the middle internal thread 12 for being threadedly coupled first externally threaded first internal thread 11 and Second bobbin diameter, the pipe cap top
Portion is provided with the end through hole 13 and liquid feed valve 14 of the 3rd diameter, the end through hole 13 and middle internal thread 12, the first internal thread
11 are sequentially communicated.
The quantitative collector 6 include the interior pipe portion 3 with bigger diameter end 15 and miner diameter end 16, be movably disposed at it is described
The reducing push rod 4 of interior pipe portion 3 and the filter screen 17 for being arranged in bigger diameter end 16, the miner diameter end 15 are provided with the threaded connection centre
Second external screw thread of internal thread 12, reducing push rod 4 include the large-diameter portion 18 for being respectively received in the bigger diameter end 16 and miner diameter end 15
With minor diameter part 19, the minor diameter part 19 is slidably connected the end through hole 13, and the large-diameter portion 18 is in close contact the big footpath
End 16 and wherein slidably, described the is more than the 3rd diameter greater diameter than Second bobbin diameter, the Second bobbin diameter.
When reducing push rod 5 filters fecal sample via filter screen 17 and is pushed to blind end 9, the control stirring of processor 8 is single
The liquid inlet volume of the mixing speed of member 10 and the concentration signal control liquid feed valve 14 detected based on concentration sensor 7.
The fecal sample quantitative collection device of the present invention is by setting quantitative collector 6 to gather and traditional stool drawing device phase
Than a greater amount of fecal samples, and sampling process is quick, accomplishs without any letup, without operating repeatedly, so as to improve collecting efficiency, subtracts
Low user psychology pressure；Collection tube 1, collection pipe cap 2 and the quantitative collector 6 of the present invention can be facilitated using threaded connection
Ground disassembly and installation, water resistance is good, effectively prevents such as lysate and fecal sample from occurring the problem of leakage in transit, peace
Full health；Collection tube 1 and liquid feed valve 14 the separation arrangement of the present invention, reagent can not be added by avoiding the harvester of prior art
The defects of solution, also farthest prevent from having such as corrosive lysate reagent solution contact skin, human body is caused
Injury, while prevent that further, just sample quantitative collection device of the invention passes through place to lysate by unnecessary pollution
The concentration signal control liquid feed valve 14 that reason device 8 is controlled the mixing speed of agitating unit 10 and detected based on concentration sensor 7 enters
Liquid measure so that the present invention can easily obtain the fecal sample of expectation concentration, and securely and reliably, hygienic and convenient.
Include using in the preferred embodiment of the described fecal sample quantitative collection device of the present invention, at the top of the pipe cap
In the pressure sensor 21 of pressure signal in the air pressure valve 20 and measurement collection tube of regulation air pressure, the pressure sensor 21 is connected
Pressure signal control pressure valve 20 is based on the processor 8 of air pressure valve 20.The present invention, can by processor automatic adjustable pressure
Avoid, due to the defects of fecal sample push is not smooth caused by air pressure or pushes error, ensuring that the detection of fecal sample
Precision.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, the harvester includes using
In the collection pallet 5 for holding excrement, the collection pallet 5 upper end side is outward extended with the Handheld Division of triangle.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, collection tube 1, collection pipe cap 2
And/or quantitative collector 6 is made up of PVC material.Fecal sample quantitative collection device uses PVC material, intensity height not cracky,
It is safer.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, the big footpath in said inner tube portion 3
The minor diameter part 19 of end 15 and/or reducing push rod 4 is provided with scale.By setting scale to improve the precision of push sample, further
Ground, when collection tube 1 is transparent material, the bigger diameter end 15 in said inner tube portion 3 is provided with scale.When collection tube 1 is opaque material
When, the minor diameter part 19 of reducing push rod 4 is provided with scale.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, the collection tube 1 and described
The first sealing ring is provided between collection pipe cap 2, the second sealing ring is provided between said inner tube portion 3 and the collection pipe cap 2.Enter one
Step ground, first sealing ring and/or the second sealing ring are O-ring seal.The present invention is using the screw thread encryption dual waterproof of seal
Measure, effectively prevent lysate and excrement from occurring the problem of leakage, safety and sanitation in transit.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, the reducing push rod 4 is work
Push rod is filled in, wherein, large-diameter portion 18 is piston head.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, outside the collection pipe cap 2
It is provided with anti-slip veins week, the top of minor diameter part 19 is provided with handle, and the liquid feed valve 14 inputs the lysate of scheduled volume.
In the preferred embodiment of the described fecal sample quantitative collection device of the present invention, the processor 8 is general
Processor, digital signal processor, application-specific integrated circuit ASIC, on-site programmable gate array FPGA, analog circuit or numeral electricity
Road, the processor 8 include memory, and the memory includes one or more read only memory ROMs, random access memory
RAM, flash memory or Electrical Erasable programmable read only memory EEPROM.
Another embodiment as shown in Figure 2, fecal sample quantitative collection device include collection tube 1, collection pipe cap 2 and determined
Measure collector 6.The collection tube 1 includes being used for the concentration sensor 7, processor 8, the and of blind end 9 for detecting fecal sample concentration
Openend 10, the openend 10 are provided with the first external screw thread of the first diameter, and the blind end 9 is provided with agitating unit 10.It is described
Collection pipe cap 2 includes being used for the pipe cap end and pipe cap top for connecting the collection tube 1, and the pipe cap end is provided with threaded connection
The middle internal thread 12 of first externally threaded first internal thread 11 and Second bobbin diameter, it is straight that the pipe cap top is provided with the 3rd
The end through hole 13 and liquid feed valve 14 in footpath, the end through hole 13 are sequentially communicated with middle internal thread 12, the first internal thread 11.Institute
Stating quantitative collector 6 includes the interior pipe portion 3 with bigger diameter end 15 and miner diameter end 16, is movably disposed at said inner tube portion 3
Reducing push rod 4 and the filter screen 17 for being arranged in bigger diameter end 16, the miner diameter end 15 are provided with the threaded connection middle internal thread 12
The second external screw thread, reducing push rod 4 includes being respectively received in the large-diameter portion 18 and minor diameter part of the bigger diameter end 16 and miner diameter end 15
19, the minor diameter part 19 is slidably connected the end through hole 13, the large-diameter portion 18 be in close contact the bigger diameter end 16 and
Wherein slidably, described is more than the 3rd diameter greater diameter than Second bobbin diameter, the Second bobbin diameter.When reducing push rod 5 is by excrement
Just sample filters via filter screen 17 and is pushed to blind end 9, and processor 8 controls the mixing speed of agitating unit 10 and is based on concentration
The liquid inlet volume for the concentration signal control liquid feed valve 14 that sensor 7 detects, the liquid feed valve 14 connect feed tube 22 to convey liquid
Reach blind end 9, the periphery of agitating unit 10 is provided with the filtering container 23 for being used to filtering out fecal sample after stirring, and the filtering is held
Device 23 allows the fecal sample less than predetermined threshold size to be leached into blind end 9 from the inside of filtering container 23.
The present embodiment further increases the accuracy of detection of harvester.Further, the internal diameter of quantitative collector 6 has three
Kind model, corresponds respectively to three kinds of different feces collection amounts.This harvester is easy to use, and stool sample quantitatively can be adopted
Collection, normal temperature transport.
In one embodiment, it is plate-like to gather pallet 5, and the upper end side of the collection pallet is outward extended with triangle
Extension, the triangle extension are the Handheld Division of collection pallet.It can be used for holding, it is mobile or very convenient by moving.
As the improvement to above-mentioned technical proposal, the collection pallet 5 is disposable collection pallet.
Fig. 3 show one embodiment of the invention using fecal sample quantitative collection device acquisition method the step of show
It is intended to, one kind utilizes, and includes the step of the acquisition method of described fecal sample quantitative collection device:
Quantitative collector 6 is inserted in excrement, and the relatively interior pipe portion 3 of reducing push rod 4 is moved up to aspirate the excrement of scheduled volume
Sample is to bigger diameter end 15.
Quantitative collector 6 is put into collection tube 1, and the first internal thread 11 is threadedly coupled first external screw thread, in the centre
Screw thread 12 is threadedly coupled the second external screw thread, and the collection pipe cap 2 connects the quantitative collector 6 and collection tube 1.
Fecal sample is filtered and is pushed to blind end 9 by reducing push rod 4 via filter screen 17, and processor 8 controls agitating unit
10 stir fecal sample with predetermined mixing speed, and the concentration signal detected based on concentration sensor 7 controls entering for liquid feed valve 14
Liquid measure.
In the method, the quantitative collector 6 being connected with collection pipe cap 2, the complete premise of ledge on top are removed
Under, the stool sample being put in clean sample collection pallet 5 is pressed with quantitative collector 6, is repeated several times, determines in confirmatory sample
Integrally put back in collection tube 1 after having been filled with sample in amount collector, screw collection pipe cap 2.While covering, press with finger
Ledge on pipe cap 2 is gathered, makes it equal with collection pipe cap 2, that is, completes sampling process.The present invention facilitates the collection of excrement,
The entirety of collection pipe cap 2 need to only be removed, quantitative collector 6 is inserted to the stool sample for being put in disposable collection pallet 5, makes bottom
The full excrement of filling, then collection tube 1 is put back to, press the quantitative collection work that reducing push rod 4 completes whole stool sample, processor
8 control agitating units 10 stir fecal sample, and the concentration signal control detected based on concentration sensor 7 with predetermined mixing speed
The liquid inlet volume of liquid feed valve 14, make stool sample with after such as nucleic acid stability agent solution thoroughly mixing, can room temperature 24h, be easy to
Normal temperature transports, without other any aids.The present invention can select the sample of model to determine according to the requirement of stool sample
Amount collection collector.After traditional acquisition mode needs clinical or scientific research personnel to receive stool sample, dispensed after balance weighs,
Not only waste time and energy, and aggravated the unstability of sample in vitro, influence follow-up experimental result.The excrement of the present invention
Collection device is simple to operate, only needs to briefly describe, can complete independently, and the quality of institute's collect specimen can be ensured, can be with
Preferably convenient clinical or scientific research personnel, greatly reduces human cost, this fecal collecting device can pass through feed liquor in pipe
Valve 14 add scheduled volume such as the liquid of nucleic acid stability agent, the sample for being stored in the inside can be played at normal temperatures steady well
It is set for using, ensures the reliability of follow-up experimental result.
Industrial applicibility
The fecal sample quantitative collection apparatus and method of the present invention can manufacture and use in medical science.
Although embodiment of the present invention is described above in association with accompanying drawing, the invention is not limited in above-mentioned
Specific embodiments and applications field, above-mentioned specific embodiment are only schematical, directiveness, rather than restricted
's.One of ordinary skill in the art is under the enlightenment of this specification and in the scope for not departing from the claims in the present invention and being protected
In the case of, the form of many kinds can also be made, these belong to the row of protection of the invention.
Claims (10)
1. a kind of fecal sample quantitative collection device, harvester includes collection tube (1), collection pipe cap (2) and quantitative collector
(6), it is characterised in that：
The collection tube (1) includes being used for the concentration sensor (7), processor (8), blind end (9) for detecting fecal sample concentration
With openend (10), the openend (10) is provided with the first external screw thread of the first diameter, and the blind end (9) is provided with agitating unit
(10)；
The collection pipe cap (2) includes being used for the pipe cap end and pipe cap top for connecting the collection tube (1), the pipe cap end
Provided with the middle internal thread (12) for being threadedly coupled first externally threaded first internal thread (11) and Second bobbin diameter, the pipe
Crown portion is provided with the end through hole (13) and liquid feed valve (14) of the 3rd diameter, the end through hole (13) and middle internal thread
(12), the first internal thread (11) is sequentially communicated；
The quantitative collector (6) includes the interior pipe portion (3) with bigger diameter end (15) and miner diameter end (16), is movably disposed at
The reducing push rod (4) in said inner tube portion (3) and the filter screen (17) for being arranged in bigger diameter end (16), the miner diameter end (15) are provided with spiral shell
Line connects the second external screw thread of the middle internal thread (12), and reducing push rod (4) includes being respectively received in the bigger diameter end (16)
With the large-diameter portion (18) and minor diameter part (19) of miner diameter end (15), the minor diameter part (19) is slidably connected the end through hole
(13), the large-diameter portion (18) is in close contact the bigger diameter end (16) and wherein slidably, and described the greater diameter than second
Diameter, the Second bobbin diameter are more than the 3rd diameter；
When reducing push rod (5) filters fecal sample via filter screen (17) and is pushed to blind end (9), processor (8) control is stirred
Mix the mixing speed of unit (10) and the liquid inlet volume of the concentration signal control liquid feed valve (14) based on concentration sensor (7) detection.
2. fecal sample quantitative collection device according to claim 1, it is characterised in that：Include being used at the top of the pipe cap
The pressure sensor (21) of pressure signal in the air pressure valve (20) and measurement collection tube of air pressure is adjusted, connects the pressure sensor
(21) and the processor (8) of air pressure valve (20) is based on pressure signal control pressure valve (20).
3. fecal sample quantitative collection device according to claim 1, it is characterised in that：The harvester includes being used for
The collection pallet (5) of excrement is held, described collection pallet (5) upper end side is outward extended with the Handheld Division of triangle.
4. fecal sample quantitative collection device according to claim 1, it is characterised in that：Liquid feed valve (14) connection is defeated
Liquor charging body reaches the feed tube (22) of blind end (9), and the periphery of agitating unit (10), which is provided with, is used to filtering out fecal sample after stirring
Filtering container (23), the filtering container (23) allows fecal sample less than predetermined threshold size from filtering container (23)
Inside is leached into blind end (9).
5. fecal sample quantitative collection device according to claim 1, it is characterised in that：The big footpath in said inner tube portion (3)
The minor diameter part (19) of end (15) and/or reducing push rod (4) is provided with scale.
6. fecal sample quantitative collection device according to claim 1, it is characterised in that：The collection tube (1) and described
The first sealing ring is provided between collection pipe cap (2), the second sealing is provided between said inner tube portion (3) and the collection pipe cap (2)
Circle.
7. fecal sample quantitative collection device according to claim 1, it is characterised in that：Collection tube (1), collection pipe cap
(2) and/or quantitative collector (6) is made up of PVC material, and the reducing push rod (4) is piston push rod, wherein, large-diameter portion (18)
For piston head.
8. fecal sample quantitative collection device according to claim 1, it is characterised in that：Outside the collection pipe cap (2)
It is provided with anti-slip veins week, minor diameter part (19) top is provided with handle, the lysate of liquid feed valve (14) the input scheduled volume.
9. fecal sample quantitative collection device according to claim 1, it is characterised in that：The processor (8) is general
Processor, digital signal processor, application-specific integrated circuit ASIC, on-site programmable gate array FPGA, analog circuit or numeral electricity
Road, the processor (8) include memory, and the memory includes one or more read only memory ROMs, random access memory
Device RAM, flash memory or Electrical Erasable programmable read only memory EEPROM.
10. a kind of acquisition method of fecal sample quantitative collection device using any one of claim 1-9, its step
Including:
In quantitative collector (6) insertion excrement, the relatively interior pipe portion (3) of reducing push rod (4) is moved up to aspirate the excrement of scheduled volume
Just sample is to bigger diameter end (15)；
Quantitative collector (6) is put into collection tube (1), and the first internal thread (11) is threadedly coupled first external screw thread, the centre
Internal thread (12) is threadedly coupled the second external screw thread, and the collection pipe cap (2) connects the quantitative collector (6) and collection tube (1)；
Fecal sample is filtered and is pushed to blind end (9) by reducing push rod (4) via filter screen (17), processor (8) control stirring
Unit (10) stirs fecal sample, and the concentration signal control feed liquor based on concentration sensor (7) detection with predetermined mixing speed
The liquid inlet volume of valve (14).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710754181.0A CN107340151B (en) | 2017-08-29 | 2017-08-29 | Quantitative fecal sample collection device and collection method |
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|---|---|---|---|
| CN201710754181.0A CN107340151B (en) | 2017-08-29 | 2017-08-29 | Quantitative fecal sample collection device and collection method |
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| CN107340151A true CN107340151A (en) | 2017-11-10 |
| CN107340151B CN107340151B (en) | 2023-06-09 |
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| CN110579371A (en) * | 2019-10-14 | 2019-12-17 | 杭州同创越诚基因科技有限公司 | A fecal sample quantitative collection device and method of use for intestinal microecological detection |
| CN112557657A (en) * | 2021-01-31 | 2021-03-26 | 陈春 | Stool dilution sampling mechanism for stool detection and control method thereof |
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| CN107340151B (en) | 2023-06-09 |
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Address after: Room 301, Building 1, No. 366 Tongyun Street, Liangzhu Street, Yuhang District, Hangzhou City, Zhejiang Province 310018 Patentee after: Zhongnuo (Hangzhou) Gene Technology Co.,Ltd. Country or region after: China Address before: Room A0101-32, Building 2, No. 452, 6th Street, Baiyang Street, Hangzhou Economic and Technological Development Zone, Hangzhou City, Zhejiang Province, 310018 Patentee before: HANGZHOU TONGCHUANG YUECHENG GENE TECHNOLOGY CO.,LTD. Country or region before: China |