CN107304033A - A kind of automatic orifice plate liquid separating meter - Google Patents

A kind of automatic orifice plate liquid separating meter Download PDF

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Publication number
CN107304033A
CN107304033A CN201610249887.7A CN201610249887A CN107304033A CN 107304033 A CN107304033 A CN 107304033A CN 201610249887 A CN201610249887 A CN 201610249887A CN 107304033 A CN107304033 A CN 107304033A
Authority
CN
China
Prior art keywords
orifice plate
wick
sample
liquid separating
automatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610249887.7A
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Chinese (zh)
Inventor
王立言
毕鲜荣
蒙玄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luoyang Huaqing Skywood Biotechnology Co Ltd
Original Assignee
Luoyang Huaqing Skywood Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luoyang Huaqing Skywood Biotechnology Co Ltd filed Critical Luoyang Huaqing Skywood Biotechnology Co Ltd
Priority to CN201610249887.7A priority Critical patent/CN107304033A/en
Publication of CN107304033A publication Critical patent/CN107304033A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C3/00Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
    • B67C3/007Applications of control, warning or safety devices in filling machinery
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C3/00Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
    • B67C3/02Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
    • B67C3/22Details
    • B67C3/28Flow-control devices, e.g. using valves

Abstract

A kind of automatic orifice plate liquid separating meter, including (X Y Z) 3 axis motion systems, sample liquid separation system, control system.(X Y Z) 3 axis motion systems include 3 stepper motors and 3 optoelectronic switches, and stepper motor is to control the motion on (X Y Z) axle of point wick-containing piece, optoelectronic switch (X Y Z) 3 axle return-to-zeros adjusting;Sample liquid separation system includes sample bottle, peristaltic pump, the sample divided in wick-containing piece and orifice plate objective table, peristaltic pump pumps sample bottle through undue wick-containing piece decile, the liquid inlet handhole plate of decile.Control system includes touch-screen and control program, control chip, and orifice plate type, orifice plate number and columns, filling liquid amount are chosen by touch-screen, controls 3 axle systems by control chip, a point wick-containing piece is moved on corresponding orifice plate and corresponding columns.This instrument can disposably realize the automatic sample of 9 pieces of orifice plates, and flux is high, control is simple, sample-adding amount is accurate, can expeditiously complete the liquid sample-adding work of a large amount of orifice plates.

Description

A kind of automatic orifice plate liquid separating meter
Technical field
The invention belongs to the liquid aliquot point filling field of liquid, the more particularly to liquid separating meter for 24,48,96 orifice plates.
Background technology
24,48,96 orifice plates are often used in microculture, ELISA experiments, in the experiment to these orifice plate liquid feedings In, it is typically used for the volley of rifle fire, board-washing machine, liquid separating meter, liquor removing workstation.Wherein the volley of rifle fire needs artificial operation, it is impossible to liberate manpower. Board-washing machine and liquid separating meter can only be generally loaded to an orifice plate, and the volume of sample-adding is generally smaller than 200mL.This 3 Plant instrument and carry out liquid feeding mainly for 96 orifice plates.Liquor removing workstation can be to multiple 24,48,96 orifice plate liquid feedings, but price Costliness, various function, complex operation, occupied area are big.In conventional microculture, ELISA experiments, liquid feeding is most Conventional operation, and traditional liquid separating meter device to 8 hole liquid feedings of row when, it is general using 8 pipelines difference liquid feedings, or adopt Liquid feeding is carried out with the asymmetric chip of pipe passage, this not only make it that the processing technology of instrument is complicated, and asymmetric chip is led Error increases between pore.
The content of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide, a kind of point of liquid precision is high, point liquid speed degree is fast and processes The simple automatic orifice plate liquid separating meter of technique.
Technical scheme is as follows:
A kind of automatic orifice plate liquid separating meter, including (X Y Z) 3 axis motion systems, sample liquid separation system, control system, the axles of XYZ 3 Kinematic system include 3 stepper motors and 3 optoelectronic switches, stepper motor to control point wick-containing piece 5 to be moved on 3 axles, Optoelectronic switch is to adjust 3 axle return-to-zeros;Sample liquid separation system includes sample bottle 11, peristaltic pump 4, point wick-containing piece 5 and orifice plate Objective table 6, the sample that peristaltic pump 4 is extracted in sample bottle 11 carries out decile, the liquid inlet handhole of decile through undue wick-containing piece 5 Plate;Control system includes touch-screen and control program, control chip 7, according to the parameter set on touch-screen, by a point wick-containing piece 5 are moved on corresponding orifice plate and corresponding columns.
Point wick-containing piece 5 of this liquid separating meter is in symmetrical structure, and a point liquid is carried out using the chip of symmetry, will produce symmetrical stream Amount, thus point liquid precision is high.
Further, point wick-containing piece 5 of this liquid separating meter is 8 deciles, can so meet the demand of most of orifice plates, again It can ensure that point liquid is carried out under appropriate flow velocity.
It is available for the parameter set to include on the touch-screen of this liquid separating meter:Plate number, panel and one pore volume.Wherein, plate number is The selective scope of orifice plate quantity is 1-9 blocks, and the time needed for automatic orifice plate liquid separating meter handles 9 blocks of plates is less than 45 seconds.Panel And the selective scope of orifice plate columns to be filled is 1-12 row.One pore volume is that the selective scope of single hole liquid volume added is 100 μ L-5mL, and error range is less than 1%.
This liquid separating meter is applied to 24 orifice plates, 48 orifice plates, 96 orifice plates, and " selection of version type " module that can be on the touchscreen is entered Row selection.Specified orifice plate number and columns may be selected by operation touch-screen, gradient liquid feeding can be achieved.
Beneficial effect:The present invention provides a kind of automatic orifice plate liquid separating meter, using symmetrically point wick-containing piece, so as to produce symmetrical Shunting, the error between each pipeline can be effectively reduced, a point liquid precision is drastically increased;Pair of point wick-containing piece in this liquid separating meter Title property, also accelerates score liquid speed degree;This liquid separating meter is simple in construction, easy to process, economical and practical.
Brief description of the drawings
Fig. 1 is the overall structure diagram of the embodiment of the present invention.
Fig. 2 is the internal structure schematic diagram of the embodiment of the present invention.
Fig. 3 is the internal structure schematic front view of the embodiment of the present invention.
Fig. 4 is the internal structure schematic top plan view of the embodiment of the present invention.
Fig. 5 divides wick-containing piece schematic diagram for the embodiment of the present invention.
Fig. 6 is the touch-screen schematic diagram of the embodiment of the present invention.
Fig. 7 is " pattern " interface in the touch-screen of the embodiment of the present invention.
Each label lists as follows in figure:
1-X shaft step motors;2-Y shaft step motors;3-Z shaft step motors;4- peristaltic pumps;5- points of wick-containing pieces;6- orifice plate objective tables; 7- control chips;8-Y axle optoelectronic switches;9-Z axle optoelectronic switches;10-X axle optoelectronic switches;11- sample bottles;12-X is moved Axle;13-Y shifting axles;14-Z shifting axles;15- housings;16- working bins.
Embodiment
Below in conjunction with technical scheme and accompanying drawing, a kind of embodiment of automatic orifice plate liquid separating meter of the present invention is described in detail.
The present invention relates to a kind of automatic orifice plate liquid separating meter, its overall structure diagram is as shown in figure 1, including housing 15 and work Make storehouse 16, the left and right side of housing 15 can have an X-rayed, point liquid process in convenient observation working bin 16.Fig. 2 gives this The internal structure schematic diagram of invention, first with touch-screen set processing parameter, by control chip 7 realize to peristaltic pump 4, X-axis stepper motor 1, y-axis stepper motor 2, the control of Z axis stepper motor 3, wherein X-axis stepper motor 1, Y-axis step Stepper motor 2 is then used for the movement for controlling point wick-containing piece 5, and Z axis stepper motor 3 is used for the rising of control hole plate objective table 6 with Drop.
Fig. 3 and Fig. 4 are respectively the main view and schematic top plan view of internal structure of the present invention, and this instrument includes (X Y Z) 3 axles Kinematic system, sample liquid separation system, control system;3 axis motion systems include 3 stepper motors and 3 optoelectronic switches, its Middle stepper motor is to control point wick-containing piece 5 to be moved on (X Y Z) axle, and return adjusting by (X Y Z) 3 axles for optoelectronic switch Zero point;Sample liquid separation system includes sample bottle 11, peristaltic pump 4, point wick-containing piece 5 and orifice plate objective table 6, and peristaltic pump 4 is extracted Sample in sample bottle 11 carries out decile, the liquid inlet handhole plate of decile through undue wick-containing piece 5.Control system includes touch-screen And control program, control chip 7, orifice plate type, orifice plate number and columns, filling liquid amount are chosen by touch-screen, pass through control Coremaking piece 7 controls 3 axis motion systems, and a point wick-containing piece 5 is moved on corresponding orifice plate and corresponding columns.
The liquid separating meter of the present invention carries out a point liquid using symmetrical chip, one-to-two, two point four, four point eight, in controlled range It inside can also continue to symmetrically distribute down.The 8 grades point schematic diagram of point wick-containing piece 5 is shown in Fig. 5.
The operating process of the present invention is as follows:
Click on the RESET key (see Fig. 6) of touch-screen in control system, X-axis stepper motor 1, y-axis stepper motor 2, Z axis step Stepper motor 3, driving (X Y Z) 3 axles zero, as divides the zeroing of wick-containing piece 5 respectively.The position of zero point is by optoelectronic switch Position is determined:Catch is connected on (X Y Z) axle, respectively along X shifting axles 12, Y shifting axles 13, Z shifting axles 14, Moved towards the position of X-axis optoelectronic switch 10, Y-axis optoelectronic switch 8, Z axis optoelectronic switch 9, catch, which is moved to, covers photoelectricity During the light path of switch, stepper motor stop motion, you can determine the dead-center position of 3 axles.
" cleaning " key (see Fig. 6) of touch-screen in control system is clicked on, peristaltic pump 4 is rotated, detergent line and point wick-containing Piece 5.After startup, " cleaning " printed words are changed into " stopping ", after pipeline and a point wick-containing piece 5 are cleaned up, click on " stopping " Key, peristaltic pump 4 stops operating.
Orifice plate type, plate number, panel, one pore volume parameter (see Fig. 6) are selected in touch-screen, wherein, plate number is hole The selective scope of plate quantity is 1-9 blocks.Panel is that the selective scope of orifice plate columns to be filled is 1-12 row.Single hole body Product is that the selective scope of single hole liquid volume added is 100 μ L-5mL.Click on "start" button.X-axis stepper motor 1, Y-axis step Stepper motor 2 is moved, above the first row that point wick-containing piece 5 is moved to first piece of orifice plate, and Z axis stepper motor 3 is moved, lifting Orifice plate objective table 6, makes the metallic sheath of point wick-containing piece 5 insert in the hole of orifice plate.Then peristaltic pump 4 is rotated, and liquid is conveyed To a point wick-containing piece 5, orifice plate is flowed into after the undue decile of wick-containing piece 5.After the completion of single-row liquid feeding, Z axis stepper motor 3 is moved, Orifice plate objective table 6 is reduced, then X-axis stepper motor 1, y-axis stepper motor 2 are moved, and a point wick-containing piece 5 is moved into second On row, Z axis stepper motor 3 is moved, lifting orifice plate objective table 6, carries out liquid filling.Such repeating motion, completes to specify panel And plate number is filling.After the completion of all filling work, point wick-containing piece 5 returns to zero point automatically.
The present invention devises " calibration " function in addition to fill water also directed to the liquid that viscosity is big, density is big.Click on " pattern " key of touch-screen in control system, into another " calibration " interface (see Fig. 7), normal mode is corresponding to be filled Dress liquid is water.Pattern 1,2,3 can confirm certain corresponding liquid for user, click on " calibration starts ", peristaltic pump 4 rotation 1min are adjusted, and then input one pore volume amount, selectable scope is 0-40mL, click on " calibration validation ", Data will be recorded in control chip, and it is achievable accurate filling to select the corresponding pattern of this liquid.

Claims (9)

1. a kind of automatic orifice plate liquid separating meter, including the axis motion systems of X Y Z 3, sample liquid separation system, control system, it is characterised in that X Y the axis motion systems of Z 3 include 3 stepper motors and 3 optoelectronic switches, the stepper motor is to control a point wick-containing piece (5) Moved on 3 axles, the optoelectronic switch is to adjust 3 axle return-to-zeros;
Sample liquid separation system includes sample bottle (11), peristaltic pump (4), point wick-containing piece (5) and orifice plate objective table (6), described to wriggle The sample that pump (4) is extracted in sample bottle (11) carries out decile, the liquid inlet handhole plate of decile through undue wick-containing piece (5);
Control system includes touch-screen and control program, control chip (7), according to the parameter set on the touch-screen, by a point wick-containing Piece (5) is moved on corresponding orifice plate and corresponding columns.
2. automatic orifice plate liquid separating meter as claimed in claim 1, it is characterised in that described point of wick-containing piece (5) is in symmetrical structure.
3. automatic orifice plate liquid separating meter as claimed in claim 2, it is characterised in that described point of wick-containing piece (5) is 8 deciles.
4. automatic orifice plate liquid separating meter as claimed in claim 1, it is characterised in that the plate number that can be set on the touch-screen is 1-9 blocks.
5. automatic orifice plate liquid separating meter as claimed in claim 4, it is characterised in that the automatic orifice plate liquid separating meter handles 9 pieces of plate institutes The time needed is less than 45 seconds.
6. automatic orifice plate liquid separating meter as claimed in claim 1, it is characterised in that the panel that can be set on the touch-screen is 1-12 Row.
7. automatic orifice plate liquid separating meter as claimed in claim 1, it is characterised in that the single hole liquid volume added that can be set on the touch-screen For 100 μ L-5mL, error range is less than 1%.
8. the automatic orifice plate liquid separating meter as described in claim any one of 1-7, it is characterised in that the orifice plate is 24 orifice plates, 48 holes Plate or 96 orifice plates.
9. the automatic orifice plate liquid separating meter as described in claim any one of 1-7, it is characterised in that by operating the touch-screen may be selected Orifice plate number and columns are specified, gradient liquid feeding can be achieved.
CN201610249887.7A 2016-04-20 2016-04-20 A kind of automatic orifice plate liquid separating meter Pending CN107304033A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610249887.7A CN107304033A (en) 2016-04-20 2016-04-20 A kind of automatic orifice plate liquid separating meter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610249887.7A CN107304033A (en) 2016-04-20 2016-04-20 A kind of automatic orifice plate liquid separating meter

Publications (1)

Publication Number Publication Date
CN107304033A true CN107304033A (en) 2017-10-31

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610249887.7A Pending CN107304033A (en) 2016-04-20 2016-04-20 A kind of automatic orifice plate liquid separating meter

Country Status (1)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101332439A (en) * 2007-06-26 2008-12-31 上海裕隆生物科技有限公司 Automatic liquor removing workstation
CN203695506U (en) * 2014-01-24 2014-07-09 北京亦庄国际诊断试剂技术有限公司 ELISA plate cleaning system
CN203938455U (en) * 2014-06-30 2014-11-12 张式琦 The Special Automatic packing instrument of a kind of nucleic
CN204214881U (en) * 2014-10-15 2015-03-18 中国航空工业集团公司北京航空材料研究院 A kind of automatic quantitative liquid feeder
CN105233527A (en) * 2015-11-06 2016-01-13 青岛顺昕电子科技有限公司 Full-automatic oscillation extraction instrument
CN205095456U (en) * 2015-10-30 2016-03-23 青岛顺昕电子科技有限公司 Vibrate extraction appearance with automatic constant volume liquid feeding device
CN205301343U (en) * 2015-12-30 2016-06-08 无锡源清天木生物科技有限公司 Full -automatic orifice plate divides liquid device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101332439A (en) * 2007-06-26 2008-12-31 上海裕隆生物科技有限公司 Automatic liquor removing workstation
CN203695506U (en) * 2014-01-24 2014-07-09 北京亦庄国际诊断试剂技术有限公司 ELISA plate cleaning system
CN203938455U (en) * 2014-06-30 2014-11-12 张式琦 The Special Automatic packing instrument of a kind of nucleic
CN204214881U (en) * 2014-10-15 2015-03-18 中国航空工业集团公司北京航空材料研究院 A kind of automatic quantitative liquid feeder
CN205095456U (en) * 2015-10-30 2016-03-23 青岛顺昕电子科技有限公司 Vibrate extraction appearance with automatic constant volume liquid feeding device
CN105233527A (en) * 2015-11-06 2016-01-13 青岛顺昕电子科技有限公司 Full-automatic oscillation extraction instrument
CN205301343U (en) * 2015-12-30 2016-06-08 无锡源清天木生物科技有限公司 Full -automatic orifice plate divides liquid device

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Application publication date: 20171031