CN107262472A - A kind of analyzer cleans disk - Google Patents
A kind of analyzer cleans disk Download PDFInfo
- Publication number
- CN107262472A CN107262472A CN201710498773.0A CN201710498773A CN107262472A CN 107262472 A CN107262472 A CN 107262472A CN 201710498773 A CN201710498773 A CN 201710498773A CN 107262472 A CN107262472 A CN 107262472A
- Authority
- CN
- China
- Prior art keywords
- reaction cup
- cup
- magnetic pole
- pole
- disk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/08—Cleaning containers, e.g. tanks
- B08B9/20—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/08—Cleaning containers, e.g. tanks
- B08B9/083—Removing scrap from containers, e.g. removing labels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/08—Cleaning containers, e.g. tanks
- B08B9/20—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
- B08B9/38—Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by using scrapers, chains, grains of shot, sand or other abrasive means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B2209/00—Details of machines or methods for cleaning hollow articles
- B08B2209/08—Details of machines or methods for cleaning containers, e.g. tanks
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Disk is cleaned the present invention relates to a kind of analyzer, magnetic bead in reaction cup is attracted by the pole pair positioned at some reaction cup run channel both sides, make magnetic bead be located at reaction cup front and rear wall on so that will not siphon away the magnetic bead in reaction cup when being inserted into imbibition injection needle imbibition in reaction cup.Meanwhile, by the change of each pole pair N S poles the magnetic bead in the gap reaction cup of imbibition is moved, magnetic bead is fully contacted with cleaning fluid, wash the nonadherent reagent in magnetic bead surfaces off.
Description
Technical field
Disk is cleaned the present invention relates to a kind of analyzer, belongs to technical field of medical instruments.
Background technology
Chemiluminescence immune assay (chemiluminescence immunoassay, CLIA), is by with high sensitivity
Chemical luminescent detecting technology be combined with the immune response of high specific, for various antigens, haptens, antibody, hormone,
The detection and analysis technology of enzyme, aliphatic acid, vitamin and medicine etc..It is generally necessary to specific biological raw material is coated on magnetic bead,
Then luminescent solution is being added, is collecting luminous intensity to carry out quantitative analysis to detectable substance.
Analyzer cleaning disk is manufactured to realize continuous measurement, and reaction cup carries out multiple on a disk rotated
Cleaning, so that the specific biological raw material not being coated on magnetic bead be washed, existing analyzer cleaning disk cleaning performance is not
It is good, and easily walk magnetic bead together cleaned liquid band, so as to influence the accuracy of measurement.
The content of the invention
The technical problem to be solved in the present invention is：To overcome above mentioned problem, there is provided a kind of more preferable analyzer of cleaning performance
Clean disk.
The technical solution adopted for the present invention to solve the technical problems is：
The present invention provides a kind of analyzer cleaning disk,
Including：
Cylinder, with circular reaction cup run channel；
Disk, is rotatably arranged in cylinder, and isometrical on disk to be placed with a circle reaction cup receiving hole, reaction cup can
Insert in reaction cup receiving hole；
Some magnetic pole groups, are arranged in cylinder and are sequentially arranged along reaction cup traffic direction, are located at if each magnetic pole group has
The pole pair of dry reaction cup run channel both sides is constituted, and each magnetic pole group at least has two magnetic for being located at reaction cup run channel both sides
Extremely right, the pole orientation of the magnet in addition to last magnetic pole group in each magnetic pole group in each pole pair is identical, two neighboring
The pole orientation of pole pair is on the contrary, the pole orientation of the magnet in each pole pair of last magnetic pole group is identical or different
And pole pair sets height gradually to reduce；
It is imbibition and the fluid injection position of imbibition injection needle on the corresponding position of last pole pair of each magnetic pole group；
Uniform shaking mechanism is provided between two magnetic pole groups.
Preferably, latter pole pair and previous magnetic pole in analyzer of the invention cleaning disk, last magnetic pole group
To declining 5-8mm compared to height.
Preferably, analyzer of the invention cleaning disk, including：Actuator is lifted, lifter plate is fixed on shaking for bottom of cylinder
Even actuator, by shaft coupling with shaking up the rocking bar that actuator is connected, is arranged on the eccentric cup at the top of rocking bar, is fixed on cylinder
The flexure strip extending at the top of disk, be provided with flexure strip for covering the lid wheel at the top of reaction cup, lid wheel bottom has
The circle wheel that can extend into reaction cup, the axis of eccentric cup and the axis of rocking bar be not conllinear, when being shaken up to reaction cup,
Lift actuator driving lifter plate to rise, shake up actuator, rocking bar, eccentric cup and risen with lifter plate, eccentric cup is by reaction cup top
Rise, the lid wheel of flexure strip is propped up at the top of reaction cup, reaction cup is fixed again, actuator startup is shaken up afterwards, passes through eccentric cup
Reaction cup is rocked, liquid in reaction cup is shaken up, lid wheel bottom has silastic-layer, and when shaking up, shaking up actuator makes reaction
Cup rotates 10-15s to a direction with 800-1200 rpms of speed.
Preferably, the distance of analyzer of the invention cleaning disk, the axis of eccentric cup and the axis of rocking bar is reaction
The 1/8-1/4 of cup width.
Preferably, the eccentric cup of the uniform shaking mechanism before analyzer of the invention cleaning disk, last magnetic pole group has magnetic
Property, magnetic pole is located at top and bottom ends.
Preferably, analyzer of the invention cleaning disk, magnetic pole group has 6, and each magnetic pole group has 2 pole pairs.
Preferably, in analyzer of the invention cleaning disk, 6 magnetic pole groups, pole pair pole orientation is followed successively by N-S, N-S,
S-N、S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S、
N-S, S-N, S-N.
The beneficial effects of the invention are as follows：The analyzer cleaning disk of the present invention, by positioned at some reaction cup run channel both sides
Pole pair attract the magnetic bead in reaction cup, magnetic bead is located on reaction cup front and rear wall so that be inserted into reaction cup
The magnetic bead in reaction cup will not be siphoned away during imbibition injection needle imbibition.Meanwhile, caused by the change of each pole pair N-S poles in imbibition
Gap reaction cup in magnetic bead move, magnetic bead is fully contacted with cleaning fluid, wash off nonadherent in magnetic bead table
The reagent in face.
Brief description of the drawings
The present invention is further described with reference to the accompanying drawings and examples.
Fig. 1 is a kind of three-dimensional structure diagram of embodiment of analyzer reagent cleaning device of the present invention；
Fig. 2 is the schematic diagram of disk upper magnetic pole arrangement of the present invention；
Fig. 3 is a kind of three-dimensional structure diagram of embodiment of present invention cleaning disc mechanism；
Fig. 4 is a kind of three-dimensional structure diagram of embodiment of uniform shaking mechanism of the present invention.
Reference is：
1- cylinders；11- reaction cup run channel；2- disks；；3- uniform shaking mechanisms；310- shakes up actuator；311- rocking bars；
321- flexure strips；322- lid wheels；330- bias cups；400- feed mechanisms；410- electromagnetic drivers；420- frames；430- is swung
Plate；500- cutting agencies；900- reaction cups.
Embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.These accompanying drawings are simplified schematic diagram, only with
Illustration illustrates the basic structure of the present invention, therefore it only shows the composition relevant with the present invention.
Embodiment 1
The present embodiment provides a kind of analyzer cleaning disk, as shown in Figure 1：
Clean disc mechanism, imbibition mechanism for filling liquid and uniform shaking mechanism 3；
Cleaning disc mechanism includes：
Cylinder 1, with circular reaction cup run channel 11；
Disk 2, is rotatably arranged in cylinder 1, isometrical on disk 2 to be placed with a circle reaction cup receiving hole, reaction cup
900 can insert in reaction cup receiving hole；
Some magnetic pole groups, being arranged on to be sequentially arranged along the traffic direction of reaction cup 900 in cylinder 1 (has 6 magnetic in such as Fig. 1
Pole group, two pole pairs are one group), each magnetic pole group has the pole pair composition positioned at some both sides of reaction cup run channel 11, often
Individual magnetic pole group at least has in two pole pairs for being located at the both sides of reaction cup run channel 11, each magnetic pole group in each pole pair
The pole orientation of magnet is identical, and conversely (such as pole pair pole orientation is followed successively by N-S, N- to the pole orientation of two neighboring pole pair
S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-
S, N-S, S-N, S-N), the pole pair of last magnetic pole group sets height gradually to reduce, latter pole pair and previous magnetic
Extremely to declining 5-8mm compared to height；
Uniform shaking mechanism 3, between two magnetic pole groups, including：Actuator is lifted, lifter plate is fixed on the bottom of cylinder 110
Shake up actuator 310, by shaft coupling with shaking up the rocking bar 311 that actuator 310 is connected, be arranged on the inclined of the top of rocking bar 311
Heart cup 330, is fixed on the flexure strip 321 for extending into the top of disk 120 on cylinder 110, flexure strip 321 and is provided with for covering
Lid wheel 322 at the top of reaction cup 900,322 bottoms of lid wheel have the circle wheel that can extend into reaction cup 900, eccentric cup 330
Axis is not conllinear with the axis of rocking bar 311, and the distance of the axis of eccentric cup 330 and the axis of rocking bar 311 is reaction
The 1/8-1/4 of 900 width of cup (is 1cm than the width of reaction cup 900, then distance is 2-2.5mm, otherwise the liquid in reaction cup 900
Can be because shaking amplitude is big and overflows), when being shaken up to reaction cup 900, lifting actuator driving lifter plate rises, and shakes up drive
Moving part 310, rocking bar 311, eccentric cup 330 rise with lifter plate, and eccentric cup 330 is by the jack-up of reaction cup 900 (so that reaction cup 900
Do not limited by reaction cup receiving hole 121), the top of reaction cup 900 props up the lid wheel 322 of flexure strip 321,900 times of reaction cup
Fix, actuator 310 is shaken up afterwards and is started, reaction cup 900 is rocked by eccentric cup 330, shake liquid in reaction cup 900
It is even, lid wheel 322 bottoms there is silastic-layer, when shaking up, when shaking up, shake up actuator 310 make reaction cup 900 to a direction with
800-1200 rpms of speed rotates 10-15s
All magnets are neodymium ferro-boron magnet.
The eccentric cup 330 of uniform shaking mechanism 3 before last magnetic pole group has magnetic, and magnetic pole is located at top and bottom ends.
The imbibition injection needle 4 of imbibition mechanism for filling liquid can be extend into when needing imbibition and fluid injection each magnetic pole group last
In reaction cup 900 on the corresponding position of individual pole pair, after imbibition and fluid injection terminate, then imbibition injection needle 4 taken out, except last
Outside a piece imbibition injection needle 4, remaining imbibition injection needle 4 is respectively provided with the function of imbibition and fluid injection, last root imbibition injection needle 4
Only there is the function of imbibition.
The analyzer disc type cleaning device of the present embodiment, by the pole pair positioned at some both sides of reaction cup run channel 11 come
Attract the magnetic bead in reaction cup 900, magnetic bead is located on the front and rear wall of reaction cup 900 so that be inserted into suction in reaction cup 900
The magnetic bead in reaction cup 900 will not be siphoned away during liquid 4 imbibition of injection needle.Meanwhile, cause inhaling by the change of each pole pair N-S poles
Magnetic bead in the gap reaction cup 900 of liquid is moved, and magnetic bead is fully contacted with cleaning fluid, is washed off nonadherent in magnetic
The reagent of bead surface.
Embodiment 2
The present embodiment provides a kind of analyzer reagent warehouse structure, as shown in Figure 1：
The different differences with embodiment 1 of the pole orientation of a last magnetic pole group, (such as pole pair pole orientation is followed successively by
S-N, S-N, S-N, S-N；N-S, N-S, N-S, N-S；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N,
S-N；N-S, N-S, S-N, S-N), the pole pair of last magnetic pole group sets height gradually to reduce, and latter magnetic pole group is with before
One magnetic pole group declines 5-8mm compared to height.
Using the above-mentioned desirable embodiment according to the present invention as enlightenment, by above-mentioned description, relevant staff is complete
Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention
Property scope is not limited to the content on specification, it is necessary to its technical scope is determined according to right.
Claims (7)
1. a kind of analyzer cleans disk, it is characterised in that
Including：
Cylinder (1), with circular reaction cup run channel (11)；
Disk (2), is rotatably arranged in cylinder (1), isometrical on disk (2) to be placed with a circle reaction cup receiving hole, reaction
Cup (900) can be inserted in reaction cup receiving hole；
Some magnetic pole groups, are arranged in cylinder (1) and are sequentially arranged along reaction cup (900) traffic direction, each magnetic pole group has position
Pole pair in some reaction cup run channel (11) both sides is constituted, and each magnetic pole group at least has two and is located at reaction cup run channel
(11) pole pair of both sides, the pole orientation phase of the magnet in addition to last magnetic pole group in each magnetic pole group in each pole pair
Together, the pole orientation of two neighboring pole pair is on the contrary, the pole orientation of the magnet in each pole pair of last magnetic pole group
Identical or different and pole pair sets height gradually to reduce；
It is imbibition and the fluid injection position of imbibition injection needle (4) on the corresponding position of last pole pair of each magnetic pole group；
Uniform shaking mechanism (3) is provided between two magnetic pole groups.
2. analyzer according to claim 1 cleans disk, it is characterised in that latter pole pair in last magnetic pole group
Height declines 5-8mm compared with previous pole pair.
3. analyzer according to claim 1 cleans disk, it is characterised in that including：Actuator is lifted, lifter plate is fixed
Actuator (310) is shaken up in cylinder (110) bottom, by shaft coupling with shaking up the rocking bar (311) that actuator (310) is connected,
The eccentric cup (330) at the top of rocking bar (311) is arranged on, the elasticity extending at the top of disk (120) on cylinder (110) is fixed on
The lid wheel (322) for covering at the top of reaction cup (900), lid wheel (322) bottom tool are provided with piece (321), flexure strip (321)
There is the circle wheel that can extend into reaction cup (900), the axis of eccentric cup (330) is not conllinear with the axis of rocking bar (311), right
When reaction cup (900) is shaken up, lifting actuator driving lifter plate rises, and shakes up actuator (310), rocking bar (311), bias
Cup (330) is risen with lifter plate, and reaction cup (900) jack-up, reaction cup are propped up flexure strip by eccentric cup (330) at the top of (900)
(321) lid wheel (322), reaction cup (900) is fixed again, and actuator (310) startup is shaken up afterwards, is passed through eccentric cup (330)
Reaction cup (900) is rocked, reaction cup (900) interior liquid is shaken up, lid wheel (322) bottom has silastic-layer, when shaking up, shakes
Even actuator (310) makes reaction cup (900) rotate 10-15s to a direction with 800-1200 rpms of speed.
4. analyzer according to claim 3 cleans disk, it is characterised in that the axis of eccentric cup (330) and rocking bar
(311) distance of axis is the 1/8-1/4 of reaction cup (900) width.
5. the analyzer cleaning disk according to claim 3 or 4, it is characterised in that the rocking evenly machine before last magnetic pole group
The eccentric cup (330) of structure (3) has magnetic, and magnetic pole is located at top and bottom ends.
6. the analyzer cleaning disk according to claim 3 or 4, it is characterised in that magnetic pole group has 6, and each magnetic pole group has 2
Individual pole pair.
7. analyzer according to claim 6 cleans disk, it is characterised in that in 6 magnetic pole groups, pole pair pole orientation according to
Secondary is N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S, S-N, S-N；N-S, N-S,
S-N、S-N；N-S, N-S, S-N, S-N.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710498773.0A CN107262472B (en) | 2017-06-27 | 2017-06-27 | Cleaning disc of analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710498773.0A CN107262472B (en) | 2017-06-27 | 2017-06-27 | Cleaning disc of analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107262472A true CN107262472A (en) | 2017-10-20 |
| CN107262472B CN107262472B (en) | 2023-04-18 |
Family
ID=60068443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710498773.0A Active CN107262472B (en) | 2017-06-27 | 2017-06-27 | Cleaning disc of analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107262472B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110586557A (en) * | 2019-09-11 | 2019-12-20 | 苏州长光华医生物医学工程有限公司 | Cleaning and separating device |
| CN113787070A (en) * | 2021-11-17 | 2021-12-14 | 南京万承生物科技有限公司 | Dynamic cleaning station of chemiluminescence immunoassay analyzer |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203426088U (en) * | 2013-08-22 | 2014-02-12 | 钟伟明 | Magnetic bead washing device |
| CN103599898A (en) * | 2013-10-29 | 2014-02-26 | 北京利德曼生化股份有限公司 | Full-automatic chemiluminescence immune analyzer magnetic bead washing device |
| CN203764601U (en) * | 2014-04-11 | 2014-08-13 | 中国科学院苏州生物医学工程技术研究所 | Magnetic microsphere cleaning device used for fully automatic chemiluminescence immunity analyzer |
| CN104655831A (en) * | 2015-03-04 | 2015-05-27 | 哈尔滨工业大学（威海） | Magnetic bead cleaning and separating device for full-automatic chemical luminescence immunity analyzer |
| CN105891113A (en) * | 2014-12-16 | 2016-08-24 | 合肥运涛光电科技有限公司 | Reaction vessel for luminescence tester and cleaning and separating mechanism thereof |
| CN207154340U (en) * | 2017-06-27 | 2018-03-30 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer cleans disk |
-
2017
- 2017-06-27 CN CN201710498773.0A patent/CN107262472B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203426088U (en) * | 2013-08-22 | 2014-02-12 | 钟伟明 | Magnetic bead washing device |
| CN103599898A (en) * | 2013-10-29 | 2014-02-26 | 北京利德曼生化股份有限公司 | Full-automatic chemiluminescence immune analyzer magnetic bead washing device |
| CN203764601U (en) * | 2014-04-11 | 2014-08-13 | 中国科学院苏州生物医学工程技术研究所 | Magnetic microsphere cleaning device used for fully automatic chemiluminescence immunity analyzer |
| CN105891113A (en) * | 2014-12-16 | 2016-08-24 | 合肥运涛光电科技有限公司 | Reaction vessel for luminescence tester and cleaning and separating mechanism thereof |
| CN104655831A (en) * | 2015-03-04 | 2015-05-27 | 哈尔滨工业大学（威海） | Magnetic bead cleaning and separating device for full-automatic chemical luminescence immunity analyzer |
| CN207154340U (en) * | 2017-06-27 | 2018-03-30 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer cleans disk |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110586557A (en) * | 2019-09-11 | 2019-12-20 | 苏州长光华医生物医学工程有限公司 | Cleaning and separating device |
| CN110586557B (en) * | 2019-09-11 | 2021-08-20 | 苏州长光华医生物医学工程有限公司 | Cleaning and separating device |
| CN113787070A (en) * | 2021-11-17 | 2021-12-14 | 南京万承生物科技有限公司 | Dynamic cleaning station of chemiluminescence immunoassay analyzer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107262472B (en) | 2023-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107262444B (en) | A kind of analyzer magnetic bead cleaning method | |
| CN107252793A (en) | A kind of analyzer disc type cleaning device | |
| JP3403839B2 (en) | Cartridge container | |
| WO2018126774A1 (en) | Automatic analysis device and sample analysis method | |
| KR20190103293A (en) | Reaction culture apparatus, immunoassay and reaction culture method | |
| US20120282681A1 (en) | Rapid Identification of Organisms in Bodily Fluids | |
| CN207154340U (en) | A kind of analyzer cleans disk | |
| CN107262472A (en) | A kind of analyzer cleans disk | |
| CN208303355U (en) | Magnetic bead cleans separator and chemical illumination immunity analysis instrument | |
| CN111279197A (en) | Magnetic separation method and automatic analyzer | |
| CN103217519A (en) | Assay device having multiple reagent cells | |
| CN106771307A (en) | Magnetic analytes collect transfer system and its method | |
| CN103760373A (en) | Cleaning device in fully-automatic chemiluminescence immunity analyzer | |
| CN207154285U (en) | A kind of analyzer disc type cleaning device | |
| CN206740787U (en) | Test solution suction device of multi-channel magnetic particle chemiluminescence immunoassay analyzer | |
| CN109499636B (en) | Pathogen immunodetection digital micro-fluidic chip and manufacturing method thereof | |
| CN208303354U (en) | Magnetic bead cleans separator and chemical illumination immunity analysis instrument | |
| CN204544866U (en) | A kind of magnetic separating device | |
| CN203178192U (en) | Dual-disc excrement analysis instrument | |
| CN206975052U (en) | A kind of analyzer disc type reaction unit | |
| CN110125075A (en) | Magnetic bead cleans separator and chemical illumination immunity analysis instrument | |
| CN107192841B (en) | One kind can drawing liquid manipulator | |
| CN210037827U (en) | Full-automatic immunofluorescence analysis device | |
| JP6479411B2 (en) | Dispensing device and clinical examination device | |
| CN206258461U (en) | A kind of reaction cup automatic flushing device on time resolution detector |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |