CN107233537A - 一种治疗银屑病的胶囊剂药物及其制备方法 - Google Patents

一种治疗银屑病的胶囊剂药物及其制备方法 Download PDF

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CN107233537A
CN107233537A CN201710572752.9A CN201710572752A CN107233537A CN 107233537 A CN107233537 A CN 107233537A CN 201710572752 A CN201710572752 A CN 201710572752A CN 107233537 A CN107233537 A CN 107233537A
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罗兴贵
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Sichuan Xingjujiao Medical Technology Co Ltd
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Abstract

本发明属于中药制剂领域,目的是根据中医对银屑病的认识机理而提供的一种治疗银屑病的胶囊剂药物,所述药物的各个组分及其质量份比如下:肿节风90~160g、黄芪90~320g、莪术(醋制)80~160g、土茯苓100~500g、补骨脂80~160g、防风80~160g、赤芍50~150g、丹参80~160g、乌梅40~80g、红花50~120g、紫草50~160g、白术80~160g、甘草30~150g;本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗银屑病的胶囊剂药物及其制备方法
技术领域
[0001] 本发明属于中药制剂领域,具体涉及其一种治疗银肩病的胶囊剂药物,特别是供 银屑病患者使用的胶囊剂药物及其制备方法的领域。 '
背景技术
[0002] 银屑病相当于中医的白疤、白壳疮、松皮癖、蛇虱、顽癣等,是一种慢性炎性、非感 染性皮肤病。该病经过缓慢,具有复发倾向。其发病机制可能与感染、代谢障碍、免疫功能、 遗传及其精神等因素有关,但至今尚未完全阐明,中医认为本病的发生与血热、血燥、血疲 等有关。银屑病患者遍布世界各地,不同民族、性别、年龄均可发病。据文献报道,银肩病的 发病率占世界人口的0 • 1%〜3%,黄种人发病率为0.1%〜0.3%,该病在人群中的发病率白种 人明显高于黄种人,黑种人次之,截止到2000年底,我国银肩病患者比1994年增加了一 倍;北方的患病率又高于南方,我国银屑病患者至少在130万〜400万左右。银屑病可分为 寻常型、脓疱型、关节病型、红皮病型,以寻常型银屑病最为常见,临床表现以白色鳞屑、薄 膜现象、点状出血为特征。尽管银肩病不威胁人的生命安全,但该病由于其慢性、缠绵反复、 顽固难愈、复发率高、严重影响患者的社会生活,造成极大的身体和心理上的痛苦,对患者 的身心健康影响很大。同时,由于该病反复发作,常需反复治疗,也给患者带来沉重的经济 负担。
[0003]那么,就如何找到一种可有效治疗银屑病的药物,是我们目前急需要解决的问题。
发明内容
[0004]随着我国中医中药学的不断发展,在治疗银肩病上,人们逐渐意识到了中医治疗 银肩病的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗银 屑病的现状,本发明的目的是在于提供一种治疗银屑病的胶囊剂药物,以解决银屑病患者 早曰恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可 有效治疗上述银屑病。
[0005]为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗银肩病的胶 囊剂药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示: 肿节风9〇〜160g、黄芪90〜320g、莪术(醋制)80〜160g、土茯苓100〜5〇〇g、补骨脂80〜 l6〇g、防风8〇〜l6〇g、赤芍50〜150g、丹参80〜160g、乌梅40〜80g、红花5〇〜120g、紫草50 〜l6〇g、白术8〇〜l6〇g、甘草30〜150g。
[0006] 一种治疗银肩病的胶囊剂药物及其制备方法,其特征在于,所述药物的各个组分 及其质量份比如下所示: 肿节风100〜140g、黄芪100〜280g、莪术(醋制)90〜140g、土茯苓II5〜420g、补骨脂90 〜140g、防风90〜140g、赤芍60〜170g、丹参90〜140g、乌梅50〜70g、红花60〜100g、紫草 6〇〜l4〇g、白术9〇〜14〇g、甘草35〜130g。
[0007] 一种治疗银肩病的胶囊剂药物及其制备方法,其特征在于,所述“最佳方案”的药 物的各个组分及其质量份比如下所示: 肿节风120g、黄芪250g、莪术(醋制)120g、土茯苓380g、补骨脂120g、防风120g、赤芍 150g、丹参120g、乌梅60g、红花90g、紫草120g、白术120g、甘草115g。
[0008] —种治疗银屑病的胶囊剂药物及其制备方法,其特征在于,所述方法包括如下步 骤制备而成: A、 将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用; B、 按照传统制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,放入药器中混合 均匀,然后制备成胶囊剂(其胶囊锁合后总长度为23.3mm,药粉容量0.4〜0.5g/粒),分装密 封即可。
[0009] —种治疗银肩病的胶囊剂药物及其制备方法,其特征在于,所述服用方法为:将制 备好的胶囊剂药物以每日三次服用,早中晚各服一次,给药量3g (6粒)/次,温开水送下,月艮 药4〜6个月后,症状全部消失,病告痊愈。已回访一年半,未见复发。
[0010]本发明组方中的各原料中药在中国药典、中国辞典以及其中华本草中均有详细的 记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效: 肿节风,性味:苦、辛、平,具有祛风除湿、活血散瘀、清热解毒之功效,用于治疗肢体麻 木、跌打损伤、骨折、妇女痛经、产后瘀滞腹痛、肺炎、争性阑尾炎、急性胃肠炎、菌痢、胆囊 炎、脓肿、口腔炎、风湿痹痛; 黄芪,性味:甘、微温,具有补气固表、利尿托毒、排脓、敛疮生肌之功效,用于治疗气虚 乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏、表虚自汗、气虚水肿、痈疽难溃、久溃不敛、 血虚瘘黄、内热消渴、慢性肾炎蛋白尿、糖尿病; 莪术(醋制),性味:味辛、苦、性温,具有行气破血、消积止痛之功效,用于治疗血气心 痛、饮食积滞、脘腹胀痛、血滞经闭、痛经、症瘕瘤痞块、跌打损伤; 土茯苓,性味:甘、淡、平,具有除湿、解毒、通利关节之功效,用于治疗湿热淋浊、带下、 痈肿、瘰疬、疥癖、梅毒及汞中毒所致的肢体拘挛、筋骨拘挛疼痛、瘰疬、疮疡; 补骨脂,性味:辛、温,具有补肾助阳之功效,用于治疗肾虚冷泻、遗尿、滑精、小便频数、 阳痿、腰膝冷痛、虚寒喘嗽、外用治白癜风等症; 防风,性味:辛甘、温,具有发表、祛风、胜湿、止痛之功效,用于治疗外感风寒、头痛、目 眩、项强、风寒湿痹、骨节酸痛、四肢挛急、破伤风等症; 赤芍,性味:苦、微寒,具有清热凉血、散瘀止痛之功效,用于治疗温毒发斑、吐血衄血、 目赤肿痛、肝郁胁痛、经闭痛经、症瘕腹痛、跌扑损伤、痈肿疮疡; 丹参,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于 治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、症瘕积聚、热痹肿痛、跌打损伤、 热入营血、烦躁不安、心烦失眠、痈疮肿毒; 乌梅,性味:味酸、性平,具有收敛生津、安蛔驱虫之功效,用于治疗久咳、虚热烦渴、久 疟、久泻、痢疾、便血、尿血、血崩、蛔厥腹痛、呕吐、钩虫病、牛皮癣、胬肉等症; 红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀 阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑瘆等症; 紫草,性味:苦、寒,具有凉血、活血、清热、解毒之功效,用于治疗温热斑疹、湿热黄疸、 紫癜、吐、衄、尿血、淋浊、热结便秘、烧伤、湿瘆、丹毒、痈疡等症; 白术,性味:味苦、甘、性温,具有健脾益气、燥湿利水、止汗、安胎之功效,用于治疗脾气 虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气 虚自汗、胎动不安等症; 甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用 于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿 痛、痈疮肿痛、小儿胎毒及药物、食物中毒。
[0011]本发明药物是基于中医治疗银肩病的原则,从药理作用及其作用机制认为:就银 屑病,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
[0012]本发明就是针对上述银屑病的治疗而提出的一种中药配方,采用该配方制备的药 物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具 体实施方式作进一步详细的描述: 实施例1: 一种治疗银肩病的胶囊剂药物,其特征在于,所述药物的各个组分及其质量份比如下 所示: 肿节风120g、黄芪250g、莪术(醋制)120g、土茯苓380g、补骨脂120g、防风120g、赤芍 150g、丹参120g、乌梅60g、红花90g、紫草120g、白术120g、甘草115g。
[0013] 实施例2: 一种治疗银屑病的胶囊剂药物,其特征在于,所述药物的各个组分及其质量份比如下 所示: 肿节风140g、黄芪280g、莪术(醋制)140g、土茯苓420g、补骨脂140g、防风140g、赤芍 170g、丹参140g、乌梅70g、红花100g、紫草140g、白术140g、甘草130g。
[0014] 实施例3: 一种治疗银屑病的胶囊剂药物,其特征在于,所述药物的各个组分及其质量份比如下 所示: 肿节风160g、黄芪320g、莪术(醋制)160g、土茯苓500g、补骨脂160g、防风160g、赤芍 150g、丹参160g、乌梅80g、红花120g、紫草160g、白术160g、甘草150g。
[0015] 典型病例 经临床诊断治疗银肩病患者共665例,年龄为22岁以上的335例,只有330例为22岁以 下。665例患者中痊愈的635例,显效的的30例,总有效率达100%。

Claims (3)

1.一种治疗银肩病的胶囊剂药物,其特征在于,所述药物的各个组分及其质量份比如 下所示: 肿节风90〜160g、黄芪90〜320g、莪术(醋制)80〜160g、土茯苓1〇〇〜500g、补骨脂80〜 l6〇g、防风SO〜l6〇g、赤芍50〜150g、丹参8〇〜16〇g、乌梅4〇〜8〇g、红花5〇〜12〇g、紫草5〇 〜l6〇g、白术8〇〜l6〇g、甘草30〜150g。
2.根据权利要求1所述的治疗银肩病的胶囊剂药物,其特征在于,所述药物的各个组分 及其质量份比如下所示: 肿节风100〜140g、黄芪1〇〇〜280g、莪术(醋制)90〜140g、土茯苓115〜420g、补骨脂90 〜140g、防风卯〜I40g、赤芍60〜170g、丹参90〜140g、乌梅50〜70g、红花㈤〜l〇〇g、紫草 60〜140g、白术90〜140g、甘草35〜130g。
3.根据权利要求1至2所述的治疗银肩病的胶囊剂药物,其特征在于,所述药物的各个 组分及其质量份比如下所示: 肿节风120g、黄芪250g、莪术(醋制)120g、土茯苓380g、补骨脂120g、防风120g、赤芍 15〇g、丹参120g、乌梅60g、红花90g、紫草120g、白术120g、甘草115g。
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