CN107233460B - External liquid for treating neck, shoulder, waist and leg pain - Google Patents

External liquid for treating neck, shoulder, waist and leg pain Download PDF

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CN107233460B
CN107233460B CN201710414616.7A CN201710414616A CN107233460B CN 107233460 B CN107233460 B CN 107233460B CN 201710414616 A CN201710414616 A CN 201710414616A CN 107233460 B CN107233460 B CN 107233460B
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radix
external liquid
weight
root
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CN107233460A (en
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李绍庆
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Pang Dongsheng
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Pang Dongsheng
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Abstract

The invention relates to an external liquid for treating neck, shoulder, waist and leg pains, belonging to the field of traditional Chinese medicine liquid preparations. The external liquid is prepared from the following raw materials in parts by weight: 50-100 parts of radix seu folium Gaultheriae Yunnanensis, 50-100 parts of Panax notoginseng, 50-100 parts of Zanthoxylum nitidum, 50-100 parts of Zhaokou, 50-100 parts of Ningpo yam rhizome, 30-50 parts of Iris root, 20-30 parts of Tongchenghu, 30-50 parts of radix Clematidis, 30-50 parts of radix cynanchi paniculatae, 30-50 parts of asarum, 30-50 parts of Liquidambar formosana, 20-30 parts of Indian stringbush root and 30-50 parts of Long Pepper. The external liquid provided by the invention is convenient to use, has a remarkable treatment effect on neck, shoulder, waist and leg pains, has no side effect, and does not relapse.

Description

External liquid for treating neck, shoulder, waist and leg pain
[ technical field ] A method for producing a semiconductor device
The invention relates to a traditional Chinese medicine liquid preparation, in particular to an external liquid for treating neck, shoulder, waist and leg pains.
[ background of the invention ]
Neck, shoulder, waist and leg pain is a common and frequently encountered disease in orthopedics clinic and is often seen in middle-aged and elderly people. The neck muscle ache, the activity limitation, the chronic lumbar muscle strain, the intervertebral disc prolapse and the bone spur bring inconvenience to the work and the life of people after the disease.
At present, many medicines for treating neck, shoulder, waist and leg pains exist in the market, most western medicine preparations are pain-relieving and pain-relieving medicines, and hormones are applied more, so that the medicines have great harm to human bodies after long-term use.
[ summary of the invention ]
The invention aims to: aiming at the existing problems, the external liquid for treating the neck, shoulder, waist and leg pains is provided, is convenient to use, has an obvious treatment effect on the neck, shoulder, waist and leg pains, has no side effect, and does not relapse.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
an external liquid for treating neck, shoulder, waist and leg pains is prepared from the following raw materials in parts by weight:
50-100 parts of radix seu folium Gaultheriae Yunnanensis, 50-100 parts of Panax notoginseng, 50-100 parts of Zanthoxylum nitidum, 50-100 parts of Zhaokou, 50-100 parts of Ningpo yam rhizome, 30-50 parts of Iris root, 20-30 parts of Tongchenghu, 30-50 parts of radix Clematidis, 30-50 parts of radix cynanchi paniculatae, 30-50 parts of asarum, 30-50 parts of Liquidambar formosana, 20-30 parts of Indian stringbush root and 30-50 parts of Long Pepper.
Preferably, the feed is prepared from the following raw materials in parts by weight:
100 parts of caulis et folium gaultheriae yunnanensis, 50 parts of panax notoginseng, 100 parts of radix zanthoxyli, 50 parts of fighting bone, 100 parts of radix achyranthis bidentatae, 50 parts of rhizoma dioscoreae nipponicae, 50 parts of iris root, 20 parts of radix cynanchi, 50 parts of radix clematidis, 30 parts of radix cynanchi paniculatae, 50 parts of asarum, 30 parts of sweet osmanthus, 30 parts of wikstroemia indica and 30 parts of long pepper.
More preferably, the feed additive is prepared from the following raw materials in parts by weight:
50 parts of caulis et folium Gaultheriae Yunnanensis, 100 parts of radix Notoginseng, 50 parts of radix Zanthoxyli, 100 parts of Zhangu, 50 parts of radix Achyranthis bidentatae, 100 parts of Ningpo Yam rhizome, 30 parts of rhizoma Iridis Tectori, 30 parts of Tongchenghu, 30 parts of radix Clematidis, 50 parts of radix Cynanchi Paniculati, 30 parts of herba asari, 50 parts of radix Dendropanacis, 20 parts of Indian Stringbush, and 50 parts of fructus Piperis Longi.
More preferably, the composition is prepared from the following raw materials in parts by weight:
80 parts of caulis et folium gaultheriae yunnanensis, 70 parts of panax notoginseng, 60 parts of radix zanthoxyli, 65 parts of fighting bone, 70 parts of radix achyranthis bidentatae, 60 parts of rhizoma dioscoreae nipponicae, 40 parts of iris root, 25 parts of marshmallow, 40 parts of radix clematidis, 40 parts of paniculate swallowwort root, 35 parts of asarum, 45 parts of sweet osmanthus, 25 parts of wikstroemia indica and 40 parts of long pepper.
A method of preparing the topical liquid of the present invention, comprising the steps of:
(1) weighing raw materials of caulis et folium Gaultheriae Yunnanensis, radix Notoginseng, radix Zanthoxyli, ZUOGU, radix Achyranthis bidentatae, Ningpo Yam rhizome, rhizoma Iridis Tectori, TONGCHANGGU, radix Clematidis, radix Cynanchi Paniculati, herba asari, radix Dendropanacis, Indian Stringbush, and fructus Piperis Longi according to weight parts; pulverizing to obtain Chinese medicinal powder;
(2) and (2) adding 75% ethanol into the mixed traditional Chinese medicine powder in the step (1) for soaking and extracting, filtering, recovering ethanol to obtain filtrate, and concentrating the filtrate to the relative density of 1.10-1.15 at 70 ℃ to obtain the external liquid.
Further, the amount of the 75% ethanol in the step (1) is 10-15 times of the weight of the traditional Chinese medicine mixed powder.
Further, the temperature of the dipping extraction in the step (1) is 25-30 ℃, and the extraction time is 5-7 days.
The raw materials used in the invention are as follows:
bone penetrating and dissipating: is prepared from root and leaf of Gaultheria forrestii Diels of Ericaceae.
Xu san qi: is prepared from Shiraia bambusicola Henn, belonging to family Hypocreales of class Ascomycetes, genus Shiraia, by sub-injection.
Two-side needle: is dried root of Zanthoxylum nitidum (Roxb.) DC. of Rutaceae plant.
Fighting bones: is the dry stem of Premna fulva Craib belonging to Verbenaceae, and is also called Tubawang and Chuanjian.
And 4, bovine seven: is root of achyranthes bidentata Blume of Amaranthaceae.
1, Ningpo Yam rhizome: is rhizome of Dioscorea nipponica Makino of Dioscoreaceae.
Iris root: is rhizome and root of Iris specula Hance of Iridaceae.
The city-passing tiger: is root or whole plant of Aristolochia debiana belonging to Aristolochiaceae and □ Aristolochia longingensis C.F.Liang.
Clematis root: is root and rhizome of Clematischensisasotbeck, Clematischensisobbeck, Clematilia gossypii C.hexapetalapall or Clemaciata manshurica Rupr.
The cunning: is dried root and rhizome of Cynanchum paniculatum (Bge.) Kitag. of Cynanchum of Asclepiadaceae.
Asarum: dried roots and rhizomes of Aristolochiaceae, Asarum heterotropoides Fr. Schmidtvar. mandshuricum (Maxim.) Kitag. Var. seoulnen Nakai, Asarum sieboldii Miq. var. seoulnen Nakai, or Asarum sieboldii Miq.
The sweet osmanthus: sassafras tzamu Hemsl, a plant of the genus Sassafras of the family lauraceae, [ pseudosassafras tzamu Lecomte; laxiflora (Hemsl.) Nakai ], was dosed with roots, bark and leaves.
Indian stringbush root: wikstroemia indica (L.) C.A.Mey, Wikstroemia indica (L.) of Wikstroemia of Thymelaeaceae, and is administered with root, root cortex, and leaf.
Long pepper picking: is dried mature or mature fruit cluster of Piper longum L. of Piperaceae.
The external liquid for treating neck, shoulder, waist and leg pains, provided by the invention, has the effects of promoting blood circulation, removing blood stasis, inducing diuresis, reducing edema and strengthening tendons and bones in the formula, namely, the formula of Tou Gu Xiao, Xue san Qi, Lian Zao, Zhan Gu, Niuqi, Ningpo Yam rhizome and Iris root, and is used as a monarch drug for reuse; the Tongcheng tiger, the clematis root, the paniculate swallowwort root, the asarum and the liquidambar formosana maxim are used as ministerial drugs for clearing heat and toxic materials, expelling wind and removing cold, and warming and activating meridians, and the Indian stringbush root is used as an adjuvant drug for strengthening the effect of a monarch drug on one hand and eliminating the side effects of pruritus, dryness and the like of the skin caused by the monarch drug on the other; long Pepper is used as a guiding drug, leads the drug effects of various drugs to enter focus, and has remarkable curative effect on cervical spondylosis, scapulohumeral periarthritis, lumbar spondylosis, gonarthrosis and other diseases by combining various drugs. The traditional Chinese medicine is applied to pain points or acupuncture points when in use, and has obvious treatment effect on neck, shoulder, waist and leg pains through a large number of clinical verifications.
[ detailed description ] embodiments
Example 1
An external liquid for treating neck, shoulder, waist and leg pains is prepared from the following raw materials in parts by weight:
100 parts of caulis et folium gaultheriae yunnanensis, 50 parts of panax notoginseng, 100 parts of radix zanthoxyli, 50 parts of fighting bone, 100 parts of radix achyranthis bidentatae, 50 parts of rhizoma dioscoreae nipponicae, 50 parts of iris root, 20 parts of radix cynanchi, 50 parts of radix clematidis, 30 parts of radix cynanchi paniculatae, 50 parts of asarum, 30 parts of sweet osmanthus, 30 parts of wikstroemia indica and 30 parts of long pepper.
The preparation method of the external liquid comprises the following steps:
(1) weighing raw materials of caulis et folium Gaultheriae Yunnanensis, radix Notoginseng, radix Zanthoxyli, ZUOGU, radix Achyranthis bidentatae, Ningpo Yam rhizome, rhizoma Iridis Tectori, TONGCHANGGU, radix Clematidis, radix Cynanchi Paniculati, herba asari, radix Dendropanacis, Indian Stringbush, and fructus Piperis Longi according to weight parts; pulverizing to obtain Chinese medicinal powder;
(2) taking the mixed traditional Chinese medicine powder in the step (1), adding 10 times of 75% ethanol by volume, soaking and extracting for 6 days at 25-30 ℃, filtering, recovering ethanol to obtain filtrate, and concentrating the filtrate to relative density of 1.10-1.15 at 70 ℃ to obtain the external liquid.
Example 2
An external liquid for treating neck, shoulder, waist and leg pains is prepared from the following raw materials in parts by weight:
50 parts of caulis et folium Gaultheriae Yunnanensis, 100 parts of radix Notoginseng, 50 parts of radix Zanthoxyli, 100 parts of Zhangu, 50 parts of radix Achyranthis bidentatae, 100 parts of Ningpo Yam rhizome, 30 parts of rhizoma Iridis Tectori, 30 parts of Tongchenghu, 30 parts of radix Clematidis, 50 parts of radix Cynanchi Paniculati, 30 parts of herba asari, 50 parts of radix Dendropanacis, 20 parts of Indian Stringbush, and 50 parts of fructus Piperis Longi.
The preparation method of the external liquid comprises the following steps:
(1) weighing raw materials of caulis et folium Gaultheriae Yunnanensis, radix Notoginseng, radix Zanthoxyli, ZUOGU, radix Achyranthis bidentatae, Ningpo Yam rhizome, rhizoma Iridis Tectori, TONGCHANGGU, radix Clematidis, radix Cynanchi Paniculati, herba asari, radix Dendropanacis, Indian Stringbush, and fructus Piperis Longi according to weight parts; pulverizing to obtain Chinese medicinal powder;
(2) taking the mixed traditional Chinese medicine powder in the step (1), adding 15 times of ethanol with the volume percentage of 75% by weight, soaking and extracting for 7 days at the temperature of 25-30 ℃, filtering, recovering the ethanol to obtain filtrate, and concentrating the filtrate to the relative density of 1.10-1.15 at the temperature of 70 ℃ to obtain the external liquid.
Example 3
An external liquid for treating neck, shoulder, waist and leg pains is prepared from the following raw materials in parts by weight:
80 parts of caulis et folium gaultheriae yunnanensis, 70 parts of panax notoginseng, 60 parts of radix zanthoxyli, 65 parts of fighting bone, 70 parts of radix achyranthis bidentatae, 60 parts of rhizoma dioscoreae nipponicae, 40 parts of iris root, 25 parts of marshmallow, 40 parts of radix clematidis, 40 parts of paniculate swallowwort root, 35 parts of asarum, 45 parts of sweet osmanthus, 25 parts of wikstroemia indica and 40 parts of long pepper.
The preparation method of the external liquid comprises the following steps:
(1) weighing raw materials of caulis et folium Gaultheriae Yunnanensis, radix Notoginseng, radix Zanthoxyli, ZUOGU, radix Achyranthis bidentatae, Ningpo Yam rhizome, rhizoma Iridis Tectori, TONGCHANGGU, radix Clematidis, radix Cynanchi Paniculati, herba asari, radix Dendropanacis, Indian Stringbush, and fructus Piperis Longi according to weight parts; pulverizing to obtain Chinese medicinal powder;
(2) taking the mixed traditional Chinese medicine powder in the step (1), adding 75% ethanol in an amount which is 12 times the weight of the mixed traditional Chinese medicine powder by volume percentage, soaking and extracting for 5 days at the temperature of 25-30 ℃, filtering, recovering the ethanol to obtain filtrate, and concentrating the filtrate to the relative density of 1.10-1.15 at the temperature of 70 ℃ to obtain the external liquid.
Comparative example 1
The external preparation of comparative example 1 was prepared without adding Indian stringbush root as an adjuvant, and the other ingredients and preparation method were the same as those of example 1.
Comparative example 2
The external preparation of comparative example 2 was prepared in the same manner as in example 1, except that piper longum was not added.
Experimental example: the external liquid has the effect of treating neck, shoulder, waist and leg pains
1. General data:
clinical observations were made on 500 patients with neck, shoulder, waist and leg pain. Of 500, 285 male and 215 female patients were aged 82 years old at the maximum and 42 years old at the minimum. 175 cases of cervical spondylosis, 78 cases of scapulohumeral periarthritis, 87 cases of lumbar spondylosis and 160 cases of knee joint disease.
2. Medicine preparation: examples 1-3, comparative examples 1 and 2.
3. The treatment method comprises the following steps:
500 cases were randomly divided into 5 groups of 100 cases, and the external liquids of examples 1 to 3 and comparative examples 1 and 2 were used for each group. The application method comprises applying 10ml of the ointment to the affected part twice a day, half a month as one treatment course, and observing the test result after three treatment courses.
4. Criteria for efficacy assessment
And (3) healing: pain disappeared, joint movement as usual;
the method has the following advantages: pain disappeared, and joint movement was painful;
and (4) invalidation: the symptoms are mild and the joint movement is still limited.
5. Test results
TABLE 1 Effect of examples 1-3, comparative examples 1 and 2 on treating neck, shoulder, waist and leg pain
Group of Recovery method Is effective Invalidation Side effects Number of recurrent cases Total effective rate
Example 1 56 40 4 0 0 96％
Example 2 58 37 5 0 0 95％
Example 3 63 34 3 0 0 97％
Comparative example 1 35 44 21 18 16 79％
Comparative example 2 49 25 26 20 21 74％
According to the clinical data, the total effective rate of the groups in examples 1-3 is higher than that of the groups in comparative examples 1 and 2, and the traditional Chinese medicine composition has no side effect and no recurrence rate; in the comparative example 1, 4 cases of dermatitis and erythema, 11 cases of local pruritus and 3 cases of dry symptom are presented; in comparative example 2, 8 cases of dermatitis and erythema, 9 cases of local pruritus, and 3 cases of dry symptom were observed. Therefore, the components in the prescription of the invention generate synergistic interaction after compatibility, thereby increasing the curative effect, reducing the side effect and being worthy of clinical popularization and application.
The above description is intended to describe in detail the preferred embodiments of the present invention, but the embodiments are not intended to limit the scope of the claims of the present invention, and all equivalent changes and modifications made within the technical spirit of the present invention should fall within the scope of the claims of the present invention.

Claims (6)

1. The external liquid for treating neck, shoulder, waist and leg pains is characterized by being prepared from the following raw materials in parts by weight:
50-100 parts of radix seu folium Gaultheriae Yunnanensis, 50-100 parts of Panax notoginseng, 50-100 parts of Zanthoxylum nitidum, 50-100 parts of Zhaokou, 50-100 parts of Ningpo yam rhizome, 30-50 parts of Iris root, 20-30 parts of Tongchenghu, 30-50 parts of radix Clematidis, 30-50 parts of radix cynanchi paniculatae, 30-50 parts of asarum, 30-50 parts of Liquidambar formosana, 20-30 parts of Indian stringbush root and 30-50 parts of Long Pepper;
the preparation method of the external liquid comprises the following steps:
(1) weighing raw materials of caulis et folium Gaultheriae Yunnanensis, radix Notoginseng, radix Zanthoxyli, ZUOGU, radix Achyranthis bidentatae, Ningpo Yam rhizome, rhizoma Iridis Tectori, TONGCHANGGU, radix Clematidis, radix Cynanchi Paniculati, herba asari, radix Dendropanacis, Indian Stringbush, and fructus Piperis Longi according to weight parts; pulverizing to obtain Chinese medicinal powder;
(2) and (2) adding 75% ethanol into the mixed traditional Chinese medicine powder in the step (1) for soaking and extracting, filtering, recovering ethanol to obtain filtrate, and concentrating the filtrate to the relative density of 1.10-1.15 at 70 ℃ to obtain the external liquid.
2. The external liquid as claimed in claim 1, which is prepared from the following raw materials in parts by weight:
100 parts of caulis et folium gaultheriae yunnanensis, 50 parts of panax notoginseng, 100 parts of radix zanthoxyli, 50 parts of fighting bone, 100 parts of radix achyranthis bidentatae, 50 parts of rhizoma dioscoreae nipponicae, 50 parts of iris root, 20 parts of radix cynanchi, 50 parts of radix clematidis, 30 parts of radix cynanchi paniculatae, 50 parts of asarum, 30 parts of sweet osmanthus, 30 parts of wikstroemia indica and 30 parts of long pepper.
3. The external liquid as claimed in claim 1, which is prepared from the following raw materials in parts by weight:
50 parts of caulis et folium Gaultheriae Yunnanensis, 100 parts of radix Notoginseng, 50 parts of radix Zanthoxyli, 100 parts of Zhangu, 50 parts of radix Achyranthis bidentatae, 100 parts of Ningpo Yam rhizome, 30 parts of rhizoma Iridis Tectori, 30 parts of Tongchenghu, 30 parts of radix Clematidis, 50 parts of radix Cynanchi Paniculati, 30 parts of herba asari, 50 parts of radix Dendropanacis, 20 parts of Indian Stringbush, and 50 parts of fructus Piperis Longi.
4. The external liquid as claimed in claim 1, which is prepared from the following raw materials in parts by weight:
80 parts of caulis et folium gaultheriae yunnanensis, 70 parts of panax notoginseng, 60 parts of radix zanthoxyli, 65 parts of fighting bone, 70 parts of radix achyranthis bidentatae, 60 parts of rhizoma dioscoreae nipponicae, 40 parts of iris root, 25 parts of marshmallow, 40 parts of radix clematidis, 40 parts of paniculate swallowwort root, 35 parts of asarum, 45 parts of sweet osmanthus, 25 parts of wikstroemia indica and 40 parts of long pepper.
5. The topical fluid according to claim 1, wherein: the amount of the 75% ethanol in the step (2) is 10-15 times of the weight of the traditional Chinese medicine mixed powder.
6. The topical fluid according to claim 1, wherein: the temperature of the dipping extraction in the step (2) is 25-30 ℃, and the extraction time is 5-7 days.
CN201710414616.7A 2017-06-05 2017-06-05 External liquid for treating neck, shoulder, waist and leg pain Active CN107233460B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058782A (en) * 2011-01-25 2011-05-18 郭芫沅 Traditional Chinese medicine powder for relieving pains in neck, shoulder, waist and leg
CN102743545A (en) * 2012-06-07 2012-10-24 无为县陡沟镇中心卫生院 Traditional Chinese medicinal ointment for treating rheumatic arthritis
CN106266428A (en) * 2016-08-19 2017-01-04 钟成德 Chinese herbal medicine for external use that preventing and treating rheumatalgia, neck lumbar vertebra be not sick and preparation method thereof
CN106668339A (en) * 2017-02-15 2017-05-17 沂南县迎辉农业开发有限公司 Medicine for reducing side effect of fusidic acid in clinical use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058782A (en) * 2011-01-25 2011-05-18 郭芫沅 Traditional Chinese medicine powder for relieving pains in neck, shoulder, waist and leg
CN102743545A (en) * 2012-06-07 2012-10-24 无为县陡沟镇中心卫生院 Traditional Chinese medicinal ointment for treating rheumatic arthritis
CN106266428A (en) * 2016-08-19 2017-01-04 钟成德 Chinese herbal medicine for external use that preventing and treating rheumatalgia, neck lumbar vertebra be not sick and preparation method thereof
CN106668339A (en) * 2017-02-15 2017-05-17 沂南县迎辉农业开发有限公司 Medicine for reducing side effect of fusidic acid in clinical use

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