CN107233458A - 一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法 - Google Patents
一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法 Download PDFInfo
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- CN107233458A CN107233458A CN201710624354.7A CN201710624354A CN107233458A CN 107233458 A CN107233458 A CN 107233458A CN 201710624354 A CN201710624354 A CN 201710624354A CN 107233458 A CN107233458 A CN 107233458A
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗小儿慢性鼻窦炎的认识机理而提供的一种治疗小儿慢性鼻窦炎的丸剂药物,所述药物的各个组分及其质量份比如下:当归120g、香附95g、苍耳95g、蜂房36g、连翘120g、冬瓜仁120g、川芎95g、石菖蒲80g、桔梗80g、红藤120g、鱼腥草200g、金荞麦360g、黄芪200g、辛夷80g、白芷95g、野菊花120g、黄芩80g、蒲公英120g、金银花280g、荆芥95g、甘草115g;本发明提供的药物是一个很好的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗小儿慢性鼻窦炎的丸剂药物,特别是供小儿慢性鼻窦炎患者使用的丸剂药物及制备方法的领域。
背景技术
祖国医学认为:儿童鼻窦炎较为常见,近年来颇受重视。其病因、症状、诊断和治疗与成人者不尽相同。各窦之发病率与其发育先后不同有关;上颌窦和筛窦较早发育,故常先受感染,额窦和蝶窦一般在2~3岁后才开始发育,故较迟受累。儿童鼻窦炎的诊断比较困难,鼻窦CT对成人鼻窦炎有重要的诊断价值。儿童鼻窦炎的诊断主要依据病史分析和细致的临床检查。儿童鼻窦炎的症状与成人不同,咳嗽、鼻漏及慢性中耳炎在儿童常见,成人则表现为慢性头痛、鼻阻塞及异常引流。
那么,就如何找到一种可有效治疗小儿慢性鼻窦炎的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗小儿慢性鼻窦炎上,人们逐渐意识到了中医治疗小儿慢性鼻窦炎的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗小儿慢性鼻窦炎的现状,本发明的目的是在于提供一种治疗小儿慢性鼻窦炎的丸剂药物,以解决小儿慢性鼻窦炎患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述小儿慢性鼻窦炎。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归60~160g、香附50~120g、苍耳60~120g、蜂房30~50g、连翘60~160g、冬瓜仁100~160g、川芎30~120g、石菖蒲30~100g、桔梗50~100g、红藤90~160g、鱼腥草150~260g、金荞麦150~500g、黄芪150~260g、辛夷30~100g、白芷30~120g、野菊花100~160g、黄芩30~100g、蒲公英90~160g、金银花150~360g、荆芥30~120g、甘草30~150g,炼蜜(每100g药粉中加炼蜜110~155g)。
一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归70~140g、香附58~105g、苍耳70~105g、蜂房38~42g、连翘70~140g、冬瓜仁115~140g、川芎38~105g、石菖蒲38~90g、桔梗58~90g、红藤100~140g、鱼腥草180~220g、金荞麦180~420g、黄芪180~220g、辛夷38~90g、白芷38~105g、野菊花115~140g、黄芩38~90g、蒲公英100~140g、金银花180~320g、荆芥38~105g、甘草38~130g,炼蜜(每100g药粉中加炼蜜110~155g)。
一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其质量份比如下所示:
当归120g、香附95g、苍耳95g、蜂房36g、连翘120g、冬瓜仁120g、川芎95g、石菖蒲80g、桔梗80g、红藤120g、鱼腥草200g、金荞麦360g、黄芪200g、辛夷80g、白芷95g、野菊花120g、黄芩80g、蒲公英120g、金银花280g、荆芥95g、甘草115g,炼蜜(每100g药粉中加炼蜜110~155g)。
一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除炼蜜外,将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水蜜丸的方法,将研磨好的极细末药物过100目筛后,混合均匀,即得药粉①;将每100g药粉中加入110~155g炼蜜,混合均匀,然后制备成丸,即得水蜜丸②,③进而烘干、消毒,分装密封即可。
一种治疗小儿慢性鼻窦炎的丸剂药物及制备方法,其特征在于,所述服用方法为:将制备好的水蜜丸药物以每日三次服用,早中晚各服一次,给药量3g /次,饭前温开水送服,30天为一个疗程,服药2~4个疗程,症状消失,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
当归,性味:味甘、辛、苦、性温,具有补血、活血、调经止痛、润燥滑肠之功效,用于治疗血虚诸证、月经不调、经闭、痛经、癥瘕结聚、崩漏、虚寒腹痛、痿痹、肌肤麻木、肠燥便难、赤痢后重、痈疽疮疡、跌扑损伤;
香附,性味:味辛、微寒,无毒,具有理气解郁、调经止痛、安胎之功效,用于治疗胁肋胀痛、乳房胀育、疝气疼痛、月经不调、脘腹痞满疼痛、嗳气吞酸、呕恶、经行腹痛、崩漏带下、胎动不安;
苍耳,性味:味苦、辛、性微寒,小毒,具有祛风、散热、除湿、解毒之功效,用于治疗感冒、头风、头晕、鼻渊、目赤、目翳、风温痹痛、拘挛麻木、风癞、疔疮、疥癣、皮肤瘙痒、痔疮、痢疾等症;
蜂房,性味:甘、平,具有祛风、功毒、杀虫、止痛之功效,用于治疗龋齿牙痛、疮疡肿毒、乳痈、瘰疬、皮肤顽癣、鹅掌风;
连翘,性味:苦、微寒,具有清热解毒、消肿散结之功效,用于治疗痈疽、瘰疠、乳痈、丹毒、风热感冒、温病初起、温热入营、高热烦渴、神昏发斑、热淋尿闭;
冬瓜仁,性味:味甘、性微寒,具有清肺化痰、消痈排脓、利湿之功效,用于治疗痰热咳嗽、肺痈、肠痈、白浊、带下、脚气、水肿、淋证等症;
川芎,性味:味辛、性温, 具有活血祛瘀、行气开郁、祛风止痛之功效,用于治疗月经不调、经闭痛经、产后瘀滞腥痛、症瘕肿块、胸胁疼痛、头痛眩晕、风寒湿痹、跌打损伤、痈疽疮疡;
石菖蒲,性味:辛、苦、温,具有化湿开胃、开窍豁痰、醒神益智之功效,用于治疗脘痞不饥、噤口下痢、神昏癫痫、健忘耳聋;
桔梗,性味:性平、味苦、辛,有小毒,具有祛痰、利咽、宣肺、排脓、利五脏、补气血、补五劳、养气之功效,用于主治咽喉肿痛、肺痈吐脓、咳嗽痰多、痢疾腹痛、胞满胁痛、口舌生疮、赤目肿痛、小便癃闭;
红藤,性味:味苦、平,无毒,具有活血通络、败毒散瘀、祛风杀虫之功效, 用于治疗治急、慢性阑尾炎、风湿痹痛、赤痢、血淋、月经不调、疳积、虫痛、跌扑损伤、清热解毒、活血、祛风、肠痈腹痛、风湿痹痛;
鱼腥草,性味:辛,寒。具有清热解毒、排脓消痈、利尿通淋之功效,用于治疗肺痈吐脓、痰热喘咳、喉哦、热痢、痈肿疮毒、热淋等症;
金荞麦,性味:微辛、涩、凉,具有清热解毒、排脓祛瘀之功效,用于治疗肺脓疡、麻疹肺炎、扁桃体周围脓肿;
黄芪,性味:甘、微温,具有补齐固表、托疮生肌之功效,用于治疗体虚自汗、久泻、脱肛、子宫脱垂、慢性肾炎、体虚浮肿、慢性溃疡、疮口久不愈合;
辛夷,性味:辛、性温,具有散风寒、通鼻窍之功效,用于治疗鼻渊、风寒感冒之头痛、鼻塞、流涕等症;
白芷,性味:味辛、性温,具有祛风除湿、通窃止痛、消肿排脓之功效,用于治疗感冒头痛、眉棱骨痛、牙痛、鼻塞、鼻渊、湿胜久泻、妇女白带、痈疽疮疡、毒蛇咬伤;
野菊花,味苦;辛;性平,具有清热解毒、疏风平肝之功效,用于治疗疔疮、痈疽、丹毒、湿疹、皮炎、风热感冒、咽喉肿痛、高血压病等症;
黄芩,性味:味苦、性寒,具有清热泻火、燥湿解毒、止血、安胎之功效,用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疔疮;
蒲公英,性味:苦、甘、寒,具有清热解毒、消肿散结、利尿通淋之功效,用于治疗疔疮肿毒、乳痈、瘰疠、目赤、咽痛、肺痈、肠痈、湿热黄疸、热淋涩痛;
金银花,性味:味甘、性寒,具有清热解毒、疏散风热、疏利咽喉、消暑除烦之功效,用于治疗暑热症、泻痢、流感、疮疖肿毒、急慢性扁桃体炎、牙周炎等病症;
荆芥,性味:味辛、微苦、性微湿,具有祛风、解表、透疹、止血之功效,用于治疗感冒发热、头痛、目痒、咳嗽、咽喉肿痛、麻疹、痈肿、疮疥、衄血、吐血、便血、崩漏、产后血晕;
甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒等症。
本发明药物是基于中医治疗小儿慢性鼻窦炎的原则,从依据小儿慢性鼻窦炎的病理机制及药理作用认为:就小儿慢性鼻窦炎,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述小儿慢性鼻窦炎的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归120g、香附95g、苍耳95g、蜂房36g、连翘120g、冬瓜仁120g、川芎95g、石菖蒲80g、桔梗80g、红藤120g、鱼腥草200g、金荞麦360g、黄芪200g、辛夷80g、白芷95g、野菊花120g、黄芩80g、蒲公英120g、金银花280g、荆芥95g、甘草115g,炼蜜(每100g药粉中加炼蜜110~155g)。
实施例2:
一种治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归140g、香附105g、苍耳105g、蜂房42g、连翘140g、冬瓜仁140g、川芎105g、石菖蒲90g、桔梗90g、红藤140g、鱼腥草220g、金荞麦420g、黄芪220g、辛夷90g、白芷105g、野菊花140g、黄芩90g、蒲公英140g、金银花320g、荆芥105g、甘草130g,炼蜜(每100g药粉中加炼蜜110~155g)。
实施例3:
一种治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归160g、香附120g、苍耳120g、蜂房50g、连翘160g、冬瓜仁160g、川芎120g、石菖蒲100g、桔梗100g、红藤160g、鱼腥草260g、金荞麦500g、黄芪260g、辛夷100g、白芷120g、野菊花160g、黄芩100g、蒲公英160g、金银花360g、荆芥120g、甘草150g,炼蜜(每100g药粉中加炼蜜110~155g)。
典型病例
经临床诊断治疗小儿慢性鼻窦炎患者共1100例,年龄为8岁以上的750例,只有350例为8岁以下。1100例患者中痊愈的820例,有效的170例,无效的110例。总有效率达90%。
Claims (3)
1.一种治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归60~160g、香附50~120g、苍耳60~120g、蜂房30~50g、连翘60~160g、冬瓜仁100~160g、川芎30~120g、石菖蒲30~100g、桔梗50~100g、红藤90~160g、鱼腥草150~260g、金荞麦150~500g、黄芪150~260g、辛夷30~100g、白芷30~120g、野菊花100~160g、黄芩30~100g、蒲公英90~160g、金银花150~360g、荆芥30~120g、甘草30~150g,炼蜜(每100g药粉中加炼蜜110~155g)。
2.根据权利要求1所述的治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归70~140g、香附58~105g、苍耳70~105g、蜂房38~42g、连翘70~140g、冬瓜仁115~140g、川芎38~105g、石菖蒲38~90g、桔梗58~90g、红藤100~140g、鱼腥草180~220g、金荞麦180~420g、黄芪180~220g、辛夷38~90g、白芷38~105g、野菊花115~140g、黄芩38~90g、蒲公英100~140g、金银花180~320g、荆芥38~105g、甘草38~130g,炼蜜(每100g药粉中加炼蜜110~155g)。
3.根据权利要求1至2所述的治疗小儿慢性鼻窦炎的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
当归120g、香附95g、苍耳95g、蜂房36g、连翘120g、冬瓜仁120g、川芎95g、石菖蒲80g、桔梗80g、红藤120g、鱼腥草200g、金荞麦360g、黄芪200g、辛夷80g、白芷95g、野菊花120g、黄芩80g、蒲公英120g、金银花280g、荆芥95g、甘草115g,炼蜜(每100g药粉中加炼蜜110~155g)。
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