CN107184838A - A kind of Chinese medicine preparation with effect of lowering blood sugar and preparation method thereof - Google Patents
A kind of Chinese medicine preparation with effect of lowering blood sugar and preparation method thereof Download PDFInfo
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- CN107184838A CN107184838A CN201710419553.4A CN201710419553A CN107184838A CN 107184838 A CN107184838 A CN 107184838A CN 201710419553 A CN201710419553 A CN 201710419553A CN 107184838 A CN107184838 A CN 107184838A
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- volatile oil
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 36
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- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 8
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Classifications
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- A61K31/33—Heterocyclic compounds
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- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- Animal Behavior & Ethology (AREA)
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- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
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- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine preparation with effect of lowering blood sugar, 60~80 parts of Sculellaria barbata is added in the formula of the Chinese medicine preparation with effect of lowering blood sugar, 70~90 parts of radix bupleuri, 70~90 parts of semen brassicae, 50~70 parts of American Ginseng, 40~60 parts of rhizome of cyrtomium, 30~60 parts of rascal, 40~60 parts of Radix Isatidis, adds appropriate amount of auxiliary materials and is made 1000, coating clothing is produced.The morbidity interpretation of the cause, onset and process of an illness, characteristics of incidence and the symptom of diabetic of the present invention for diabetes, plurality of Chinese is pressed into certain part by weight compatibility, can nourishing Yin and promoting production of body fluid, qi and activate blood circulation, tonifying liver invigorating the spleen, heat-clearing drop is dry, good synergy is not only reached, and safety has no adverse reaction, and is especially suitable for diabetic and takes for a long time.
Description
Technical field
The present invention relates to pharmaceutical field, specially a kind of Chinese medicine preparation with effect of lowering blood sugar and preparation method thereof.
Background technology
Diabetes, the traditional Chinese medical science claims diabetes, be it is a kind of because internal insulin is absolute or relative deficiency caused by a series of face
Bed syndrome, is a kind of common, multiple, adjoint lifelong disease.Its incidence of disease has the trend increased year by year, in flourishing state
Family has been listed in the third-largest disease after angiocardiopathy and diabetes.Current diabetes are to human health risk maximum
It is a variety of chronic complicating diseases produced on the basis of artery sclerosis and microangiopathies, such as diabetic cardiomyopathy, diabetic keratopathy
Acromelic gangrene, diabetic cerebrovascular disease, nephrosis, BDR and DPN etc..Because of glycosuria
Disease causes blind person 10~25 times more than common people, current BDR turned into four big main blinding diseases it
One；20 times more than diabetic gangrene and amputee ratio common people；Diabetes are compared with non-diabetic person's cardiovascular system incidence of disease with dying of illness
Rate is high 2~3 times；Diabetes cause renal failure 17 times more than nephrosis.In a word, diabetes and its chronic complicating diseases are strong to the mankind
The harm of health is extremely serious, has caused the great attention of world-wide medical circle.Though TCM Treatment of Diabetes has been achieved
Certain methods and experience, but at present still without really popularity and the experience and achievement that use can be worth.
In addition, the existing Chinese medicine preparation with effect of lowering blood sugar is typically all various medicinal materials is brewed into liquid together, its
Impurity easily is infiltrated, causes the quality of Chinese medicine unstable, and the shelf-life is shorter.
For the unstable phenomenon of the Chinese medicine preparation quality with effect of lowering blood sugar, the present invention is carried out to its production technology
Improve, expectation can improve the stability of the Chinese medicine preparation with effect of lowering blood sugar in process of production, drug quality and drug effect,
And the term of validity of Chinese medicine preparation of the extension with effect of lowering blood sugar.
The content of the invention
The technical problem to be solved in the present invention is to overcome existing defect new to have effect of lowering blood sugar there is provided a kind of
Chinese medicine preparation.
In order to solve the above-mentioned technical problem, the invention provides following technical scheme：
A kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 160
~200 parts, 160~200 parts of the capsule of weeping forsythia, 60~80 parts of Chinese cassia tree, 80~100 parts of the stem of noble dendrobium, 60~80 parts of lophatherum gracile, Taxus 100~
120 parts, 100~120 parts of reed rhizome, 100~120 parts of semen brassicae, 80~100 parts of sun-dried ginseng, 0.5~1.5 part of evodia rutaecarpa, long-noded pit viper
100~110 parts of tongue grass, 40~60 parts of vitamin C, 0.8~1.2mL of oligosaccharide, 60~80 parts of Sculellaria barbata, 70~90 parts of radix bupleuri,
50~70 parts of American Ginseng, 40~60 parts of rhizome of cyrtomium, 30~60 parts of rascal, 40~60 parts of Radix Isatidis adds appropriate amount of auxiliary materials and is made 1000
Piece, coating clothing is produced.
The Chinese herbaceous peony leaf extract, which is prepared by the following method, to be obtained：Chinese herbaceous peony leaf is taken, using 0~95% ethanol to be molten
Matchmaker, is flowed back 1~8 time, reclaims ethanol, and extract solution is concentrated into 10~20Bx, and in standing 24~36h at 1~4 DEG C, centrifugation is removed
Precipitation is gone, it is standby by supernatant concentration to 20~40Bx；
Further, the new Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony
It is 180 parts of leaf extract, 180 parts of the capsule of weeping forsythia, 72 parts of Chinese cassia tree, 90 parts of the stem of noble dendrobium, 72 parts of lophatherum gracile, 108 parts of Taxus, 108 parts of reed rhizome, white
108 parts of mustard seed, 90 parts of sun-dried ginseng, 1.05 parts of evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, oligosaccharide 1.08mL,
70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts of Radix Isatidis adds appropriate amount of auxiliary materials and is made
1000, coating clothing is produced.
In order to improve the stability of the Chinese medicine preparation with effect of lowering blood sugar in process of production, drug quality and medicine
Effect, and extension have the term of validity of the Chinese medicine preparation of effect of lowering blood sugar, and applicant is to the Chinese medicine preparation with effect of lowering blood sugar
Preparation method improve, step of preparation process is as follows：
1) 160~200 parts of the capsule of weeping forsythia, 160~200 parts of Chinese herbaceous peony leaf extract, 60~80 parts of Chinese cassia tree is taken to be placed in volatile oil extracting
In device, 8 times of waters are added, with extraction by steam distillation volatile oil, 4 hours is extracted, is layered after condensation, obtains volatile oil,
It is standby；
2) dregs of a decoction after volatile oil and 80~100 parts of the stem of noble dendrobium, 60~80 parts of lophatherum gracile, reed rhizome 100~120 will 1) be extracted
Part, 100~120 parts of semen brassicae, 80~100 parts of sun-dried ginseng, 60~80 parts of Sculellaria barbata, 70~90 parts of radix bupleuri, American Ginseng 50~70
Part, 40~60 parts of rhizome of cyrtomium, 30~60 parts of rascal, 12 taste medicinal material mixing of Radix Isatidis 40~60 part, add 10 times of decoctings and boil 1
Hour, 8 times of decoctings are added after filtering and are boiled 1 hour, filters, merges filtrate twice；
3) 100~120 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, merges filter
Liquid, reclaims ethanol, and adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；0.8~1.2mL of volatile oil and peppermint oil of gained in adding 1), is mixed；
6) add 0.5~1.5 part of major pharmaceutical evodia rutaecarpa, it is 100~110 parts of oldenlandia diffusa, 40~60 parts of vitamin C, mixed
Even, tabletting, coating clothing is produced.
Further, the step of preparation process of the Chinese medicine preparation with effect of lowering blood sugar is as follows：
1) take 180 parts of the capsule of weeping forsythia, 180 parts of Chinese herbaceous peony leaf extract, 72 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of water
Amount, with extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) will 1) extract 90 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil, 72 parts of lophatherum gracile, 108 parts of reed rhizome, 108 parts of semen brassicae,
90 parts of sun-dried ginseng, 70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts, 12 of Radix Isatidis
Taste medicinal material is mixed, and is added 10 times of decoctings and is boiled 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merging is filtered twice
Liquid；
3) 108 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 1.08mL of gained in adding 1), are mixed；
6) 1.05 parts of major pharmaceutical evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, mixing, tabletting, coating are added
Clothing is produced.
The present invention the Chinese medicine preparation with effect of lowering blood sugar compared with prior art, with following beneficial effect：
The present invention improves the stability of the Chinese medicine preparation with effect of lowering blood sugar in process of production, drug quality and medicine
Effect, and extension have the term of validity of the Chinese medicine preparation of effect of lowering blood sugar, and after placing 36 months at room temperature, each component content is still big
In 99.6% so that the production technology of the Chinese medicine preparation with effect of lowering blood sugar has substantial breakthrough and technological progress.This
Invention is matched somebody with somebody plurality of Chinese by certain part by weight for the morbidity interpretation of the cause, onset and process of an illness, characteristics of incidence and the symptom of diabetic of diabetes
5, can nourishing Yin and promoting production of body fluid, qi and activate blood circulation, tonifying liver invigorating the spleen, heat-clearing drop is dry, does not only reach good synergy, and safety is invariably
Good reaction, is especially suitable for diabetic and takes for a long time.
Embodiment
The preferred embodiments of the present invention are illustrated below, it will be appreciated that preferred embodiment described herein is only used
In the description and interpretation present invention, it is not intended to limit the present invention.
Embodiment 1
A kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 160
Part, 160 parts of the capsule of weeping forsythia, 60 parts of Chinese cassia tree, 80 parts of the stem of noble dendrobium, 60 parts of lophatherum gracile, 100 parts of Taxus, 100 parts of reed rhizome, 100 parts of semen brassicae,
80 parts of sun-dried ginseng, 0.5 part of evodia rutaecarpa, 100 parts of oldenlandia diffusa, 40 parts of vitamin C, oligosaccharide 0.8mL, 80 parts of Sculellaria barbata, bavin
90 parts recklessly, 70 parts of American Ginseng, 60 parts of rhizome of cyrtomium, 60 parts of rascal, 60 parts of Radix Isatidis adds appropriate amount of auxiliary materials and 1000, coating clothing is made
Produce.
The formula has the step of preparation process of the Chinese medicine preparation of effect of lowering blood sugar as follows：
1) take 160 parts of the capsule of weeping forsythia, 160 parts of Chinese herbaceous peony leaf extract, 60 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of water
Amount, with extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) will 1) extract 80 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil, 72 parts of lophatherum gracile, 100 parts of reed rhizome, 100 parts of semen brassicae,
80 parts of sun-dried ginseng, 80 parts of Sculellaria barbata, 90 parts of radix bupleuri, 70 parts of American Ginseng, 60 parts of rhizome of cyrtomium, 60 parts of rascal, 60 parts, 12 of Radix Isatidis
Taste medicinal material is mixed, and is added 10 times of decoctings and is boiled 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merging is filtered twice
Liquid；
3) 100 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 0.8mL of gained in adding 1), are mixed；
6) 0.5 part of major pharmaceutical evodia rutaecarpa, 100 parts of oldenlandia diffusa, 40 parts of vitamin C, mixing, tabletting, coating clothing are added
Produce.
Embodiment 2
A kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 200
Part, 200 parts of the capsule of weeping forsythia, 80 parts of Chinese cassia tree, 100 parts of the stem of noble dendrobium, 80 parts of lophatherum gracile, 120 parts of Taxus, 120 parts of reed rhizome, 120 parts of semen brassicae,
100 parts of sun-dried ginseng, 1.5 parts of evodia rutaecarpa, 110 parts of oldenlandia diffusa, 60 parts of vitamin C, oligosaccharide 1.2mL, 60 parts of Sculellaria barbata,
70 parts of radix bupleuri, 50 parts of American Ginseng, 40 parts of rhizome of cyrtomium, 30 parts of rascal, 40 parts of Radix Isatidis adds appropriate amount of auxiliary materials and 1000, coating is made
Clothing is produced.
The formula has the step of preparation process of the Chinese medicine preparation of effect of lowering blood sugar as follows：
1) take 200 parts of the capsule of weeping forsythia, 200 parts of Chinese herbaceous peony leaf extract, 80 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of water
Amount, with extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) will 1) extract 100 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil, 80 parts of lophatherum gracile, 120 parts of reed rhizome, 120 parts of semen brassicae,
100 parts of sun-dried ginseng, 60 parts of Sculellaria barbata, 70 parts of radix bupleuri, 50 parts of American Ginseng, 40 parts of rhizome of cyrtomium, 30 parts of rascal, 40 parts of Radix Isatidis, 12
Position taste medicinal material mixing, adds 10 times of decoctings and boils 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merging is filtered twice
Liquid；
3) 120 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, be cooled to paraffin and float on liquid level, remove paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 0.8mL of gained in adding 1), are mixed；
6) 1.5 parts of major pharmaceutical evodia rutaecarpa, 110 parts of oldenlandia diffusa, 60 parts of vitamin C, mixing, tabletting, coating clothing are added
Produce.
Embodiment 3
A kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 180
Part, 180 parts of the capsule of weeping forsythia, 70 parts of Chinese cassia tree, 90 parts of the stem of noble dendrobium, 70 parts of lophatherum gracile, 110 parts of Taxus, 110 parts of reed rhizome, 110 parts of semen brassicae,
90 parts of sun-dried ginseng, 1.0 parts of evodia rutaecarpa, 105 parts of oldenlandia diffusa, 50 parts of vitamin C, oligosaccharide 1.0mL, 70 parts of Sculellaria barbata, bavin
80 parts recklessly, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts of Radix Isatidis adds appropriate amount of auxiliary materials and 1000, coating clothing is made
Produce.
The formula has the step of preparation process of the Chinese medicine preparation of effect of lowering blood sugar as follows：
1) take 180 parts of the capsule of weeping forsythia, 180 parts of Chinese herbaceous peony leaf extract, 70 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of water
Amount, with extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) will 1) extract 90 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil, 70 parts of lophatherum gracile, 110 parts of reed rhizome, 110 parts of semen brassicae,
90 parts of sun-dried ginseng, 70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts, 12 of Radix Isatidis
Taste medicinal material is mixed, and is added 10 times of decoctings and is boiled 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merging is filtered twice
Liquid；
3) 110 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, be cooled to paraffin and float on liquid level, remove paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 0.8mL of gained in adding 1), are mixed；
6) 1 part of major pharmaceutical evodia rutaecarpa, 105 parts of oldenlandia diffusa, 50 parts of vitamin C, mixing, tabletting are added, coating clothing is
.
Embodiment 4
A kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 180
Part, 180 parts of the capsule of weeping forsythia, 72 parts of Chinese cassia tree, 90 parts of the stem of noble dendrobium, 72 parts of lophatherum gracile, 108 parts of Taxus, 108 parts of reed rhizome, 108 parts of semen brassicae,
90 parts of sun-dried ginseng, 1.05 parts of evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, oligosaccharide 1.08mL, Sculellaria barbata 70
Part, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts of Radix Isatidis adds appropriate amount of auxiliary materials and 1000, bag is made
Film clothing is produced.
The formula has the step of preparation process of the Chinese medicine preparation of effect of lowering blood sugar as follows：
1) take 180 parts of the capsule of weeping forsythia, 180 parts of Chinese herbaceous peony leaf extract, 72 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of water
Amount, with extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) will 1) extract 90 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil, 72 parts of lophatherum gracile, 108 parts of reed rhizome, 108 parts of semen brassicae,
90 parts of sun-dried ginseng, 70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts, 12 of Radix Isatidis
Taste medicinal material is mixed, and is added 10 times of decoctings and is boiled 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merging is filtered twice
Liquid；
3) 108 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the leaching that relative density at 60 DEG C is 1.08~1.10
Cream, is dried under reduced pressure, and dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, hard magnesium 30 are added
Part, it is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 1.08mL of gained in adding 1), are mixed；
6) 1.05 parts of major pharmaceutical evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, mixing, tabletting, coating are added
Clothing is produced.
Finally it should be noted that：The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention,
Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, it still may be used
To be modified to the technical scheme described in foregoing embodiments, or equivalent substitution is carried out to which part technical characteristic.
Within the spirit and principles of the invention, any modification, equivalent substitution and improvements made etc., should be included in the present invention's
Within protection domain.
Claims (6)
1. a kind of Chinese medicine preparation with effect of lowering blood sugar, is made up of the medicine of following weight proportion：Chinese herbaceous peony leaf extract 160~
200 parts, 160~200 parts of the capsule of weeping forsythia, 60~80 parts of Chinese cassia tree, 80~100 parts of the stem of noble dendrobium, 60~80 parts of lophatherum gracile, Taxus 100~120
Part, 100~120 parts of reed rhizome, 100~120 parts of semen brassicae, 80~100 parts of sun-dried ginseng, 0.5~1.5 part of evodia rutaecarpa, oldenlandia
100~110 parts of grass, 40~60 parts of vitamin C, 0.8~1.2mL of oligosaccharide, 60~80 parts of Sculellaria barbata, 70~90 parts of radix bupleuri, west
50~70 parts of American ginseng, 40~60 parts of rhizome of cyrtomium, 30~60 parts of rascal, 40~60 parts of Radix Isatidis adds appropriate amount of auxiliary materials and is made 1000,
Coating clothing is produced.
2. a kind of Chinese medicine preparation with effect of lowering blood sugar as claimed in claim 1, is made up of the medicine of following weight proportion：
160 parts of Chinese herbaceous peony leaf extract, 160 parts of the capsule of weeping forsythia, 60 parts of Chinese cassia tree, 80 parts of the stem of noble dendrobium, 60 parts of lophatherum gracile, 100 parts of Taxus, reed rhizome 100
Part, 100 parts of semen brassicae, 80 parts of sun-dried ginseng, 0.5 part of evodia rutaecarpa, 100 parts of oldenlandia diffusa, 40 parts of vitamin C, oligosaccharide
0.8mL, 60 parts of Sculellaria barbata, 70 parts of radix bupleuri, 50 parts of American Ginseng, 40 parts of rhizome of cyrtomium, 30 parts of rascal, 40 parts of Radix Isatidis is added appropriate auxiliary
Material is made 1000, and coating clothing is produced.
3. a kind of Chinese medicine preparation with effect of lowering blood sugar as claimed in claim 1, is made up of the medicine of following weight proportion：
200 parts of Chinese herbaceous peony leaf extract, 200 parts of the capsule of weeping forsythia, 80 parts of Chinese cassia tree, 100 parts of the stem of noble dendrobium, 80 parts of lophatherum gracile, 120 parts of Taxus, reed rhizome 120
Part, 120 parts of semen brassicae, 100 parts of sun-dried ginseng, 1.5 parts of evodia rutaecarpa, 110 parts of oldenlandia diffusa, 60 parts of vitamin C, oligosaccharide
1.2mL, 80 parts of Sculellaria barbata, 90 parts of radix bupleuri, 70 parts of American Ginseng, 40~60 parts of rhizome of cyrtomium, 30~60 parts of rascal, Radix Isatidis 40~60
Part, add appropriate amount of auxiliary materials and be made 1000, coating clothing is produced.
4. a kind of Chinese medicine preparation with effect of lowering blood sugar as claimed in claim 1, is made up of the medicine of following weight proportion：
180 parts of Chinese herbaceous peony leaf extract, 180 parts of the capsule of weeping forsythia, 72 parts of Chinese cassia tree, 90 parts of the stem of noble dendrobium, 72 parts of lophatherum gracile, 108 parts of Taxus, reed rhizome 108
Part, 108 parts of semen brassicae, 90 parts of sun-dried ginseng, 1.05 parts of evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, oligosaccharide
1.08mL, 70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts of Radix Isatidis is added appropriate auxiliary
Material is made 1000, and coating clothing is produced.
5. a kind of preparation method of Chinese medicine preparation with effect of lowering blood sugar as described in Claims 1 to 4 is any, its feature exists
In step of preparation process is as follows：
1) 160~200 parts of the capsule of weeping forsythia, 160~200 parts of Chinese herbaceous peony leaf extract, 60~80 parts of Chinese cassia tree is taken to be placed in volatile oil extractor,
8 times of waters are added, with extraction by steam distillation volatile oil, 4 hours is extracted, is layered after condensation, obtains volatile oil, it is standby；
2) 80~100 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil will 1) be extracted, it is 60~80 parts of lophatherum gracile, 100~120 parts of reed rhizome, white
100~120 parts of mustard seed, 80~100 parts of sun-dried ginseng, 60~80 parts of Sculellaria barbata, 70~90 parts of radix bupleuri, 50~70 parts of American Ginseng, pass through
Many 40~60 parts, 30~60 parts of rascal, 12 taste medicinal material mixing of Radix Isatidis 40~60 part, add 10 times of decoctings and boil 1 hour,
8 times of decoctings are added after filtering to boil 1 hour, are filtered, are merged filtrate twice；
3) 100~120 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate is returned
Ethanol is received, adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the medicinal extract that relative density at 60 DEG C is 1.08~1.10,
It is dried under reduced pressure, dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, 30 parts of hard magnesium are added,
It is that adhesive is pelletized with 94mL95% ethanol；0.8~1.2mL of volatile oil and peppermint oil of gained in adding 1), is mixed；
6) 0.5~1.5 part of major pharmaceutical evodia rutaecarpa, 100~110 parts of oldenlandia diffusa, 40~60 parts of vitamin C, mixing are added,
Tabletting, coating clothing is produced.
6. a kind of preparation method of the Chinese medicine preparation with effect of lowering blood sugar as claimed in claim 3, it is characterised in that prepare
Processing step is as follows：
1) take 180 parts of the capsule of weeping forsythia, 180 parts of Chinese herbaceous peony leaf extract, 72 parts of Chinese cassia tree to be placed in volatile oil extractor, add 8 times of waters, with
Extraction by steam distillation volatile oil, extracts 4 hours, is layered after condensation, obtains volatile oil, standby；
2) 90 parts of the dregs of a decoction and the stem of noble dendrobium after volatile oil will 1) be extracted, it is 72 parts of lophatherum gracile, 108 parts of reed rhizome, 108 parts of semen brassicae, sun-dried
90 parts of ginseng, 70 parts of Sculellaria barbata, 80 parts of radix bupleuri, 60 parts of American Ginseng, 50 parts of rhizome of cyrtomium, 45 parts of rascal, 50 parts of Radix Isatidis, 12 taste medicines
Material is mixed, and is added 10 times of decoctings and is boiled 1 hour, and 8 times of decoctings are added after filtering and are boiled 1 hour, are filtered, merge filtrate twice；
3) 108 parts of use of Taxus, 60% ethanol heating and refluxing extraction is secondary, every time 4 hours, filtering, and merging filtrate reclaims second
Alcohol, adding paraffin makes dissolving, is cooled to paraffin and floats on liquid level, except paraffin layer；
4) filtrate obtained by merging 2) and 3) middle gained filtrate, are condensed into the medicinal extract that relative density at 60 DEG C is 1.08~1.10,
It is dried under reduced pressure, dried cream powder is made；
5), into dried cream powder, 1176 parts of lactose, 200 parts of talcum powder, 300 parts of sodium carboxymethyl starch, 30 parts of hard magnesium are added,
It is that adhesive is pelletized with 94mL95% ethanol；The volatile oil and peppermint oil 1.08mL of gained in adding 1), are mixed；
6) 1.05 parts of major pharmaceutical evodia rutaecarpa, 105 parts of oldenlandia diffusa, 49.5 parts of vitamin C, mixing, tabletting are added, coating clothing is
.
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| CN102580030A (en) * | 2012-03-06 | 2012-07-18 | 北京张润琪医学研究院 | External traditional Chinese medicine composition having effect of reducing blood sugar, preparation prepared from the external traditional Chinese medicine composition, and their preparation method |
| CN104189588A (en) * | 2014-09-11 | 2014-12-10 | 江西九华药业有限公司 | Vitamin C Yinqiao tablets and preparation method thereof |
| CN106075141A (en) * | 2016-07-26 | 2016-11-09 | 贵州医科大学 | A kind of anti-tumor Chinese medicine and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102580030A (en) * | 2012-03-06 | 2012-07-18 | 北京张润琪医学研究院 | External traditional Chinese medicine composition having effect of reducing blood sugar, preparation prepared from the external traditional Chinese medicine composition, and their preparation method |
| CN104189588A (en) * | 2014-09-11 | 2014-12-10 | 江西九华药业有限公司 | Vitamin C Yinqiao tablets and preparation method thereof |
| CN106075141A (en) * | 2016-07-26 | 2016-11-09 | 贵州医科大学 | A kind of anti-tumor Chinese medicine and preparation method thereof |
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