CN107183678A - A kind of Periostracum cicadae instant powder and preparation method thereof - Google Patents
A kind of Periostracum cicadae instant powder and preparation method thereof Download PDFInfo
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- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 claims abstract description 23
- 230000008569 process Effects 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims description 49
- 239000000706 filtrate Substances 0.000 claims description 28
- 239000000284 extract Substances 0.000 claims description 27
- 239000004480 active ingredient Substances 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 108090000790 Enzymes Proteins 0.000 claims description 18
- 102000004190 Enzymes Human genes 0.000 claims description 18
- 229940088598 enzyme Drugs 0.000 claims description 18
- 238000000605 extraction Methods 0.000 claims description 15
- 239000006286 aqueous extract Substances 0.000 claims description 12
- 239000002002 slurry Substances 0.000 claims description 9
- 239000005913 Maltodextrin Substances 0.000 claims description 7
- 229920002774 Maltodextrin Polymers 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 7
- 239000000919 ceramic Substances 0.000 claims description 7
- 229940059442 hemicellulase Drugs 0.000 claims description 7
- 108010002430 hemicellulase Proteins 0.000 claims description 7
- 229940035034 maltodextrin Drugs 0.000 claims description 7
- 239000012528 membrane Substances 0.000 claims description 7
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 108010059892 Cellulase Proteins 0.000 claims description 6
- 229940106157 cellulase Drugs 0.000 claims description 6
- 230000001804 emulsifying effect Effects 0.000 claims description 5
- 239000006185 dispersion Substances 0.000 claims description 4
- 238000004945 emulsification Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 238000000926 separation method Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 108090000637 alpha-Amylases Proteins 0.000 claims description 3
- 102000004139 alpha-Amylases Human genes 0.000 claims description 3
- 229940024171 alpha-amylase Drugs 0.000 claims description 3
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- 238000002137 ultrasound extraction Methods 0.000 claims description 2
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- 230000036541 health Effects 0.000 abstract description 4
- 230000036039 immunity Effects 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 3
- 235000013402 health food Nutrition 0.000 abstract description 2
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- 239000000203 mixture Substances 0.000 description 6
- 241000233866 Fungi Species 0.000 description 5
- 241001248610 Ophiocordyceps sinensis Species 0.000 description 5
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- 241001625026 Cordyceps cicadae Species 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 241001264174 Cordyceps militaris Species 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
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- 230000035764 nutrition Effects 0.000 description 2
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- 241001480006 Clavicipitaceae Species 0.000 description 1
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 1
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- 230000036592 analgesia Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
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- 108010019077 beta-Amylase Proteins 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 1
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 1
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- 208000021822 hypotensive Diseases 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
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- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention belongs to health product technology field, and in particular to a kind of Periostracum cicadae instant powder, and further disclose its preparation method.Periostracum cicadae instant powder of the present invention is using Periostracum cicadae as primary raw material, instant powder is made using common process, body immunity can be effectively improved, with improve sleep, it is antifatigue the effects such as, obtained instant powder, it can be directly used for taking, the raw material that can also act on medicine, health food etc. is utilized.
Description
Technical field
The invention belongs to health product technology field, and in particular to a kind of Periostracum cicadae instant powder, and further disclose its system
Preparation Method.
Background technology
Periostracum cicadae, also known as golden cicada are spent, are commonly called as big cordyceps sinensis, are the golden cicada flower (Isariacicadae of artificial cultivation
Miquel), it is dry composite body that cicada class nymph is parasitized by Clavicipitaceae Cordyceps sinensis fungus Paecilomyces cicadae, belongs to worm life true
Bacterium.In the whole world it has been found that 504 kinds of cordyceps sinensis in, Periostracum cicadae, cordyceps sinensis are only two kinds therein, be China tradition
One of rare traditional Chinese medicine, be distributed mainly on the ground such as Sichuan, Jiangsu, Zhejiang, Fujian, Anhui, the Yunnan Province of China.
Periostracum cicadae is the marvellous biology that a kind of profile has " animal " and " plant " morphological feature, and its root is the larva of cicada
Body；Its flower grows out from single or 2-3 cicada larva head, and how long is flower about one-inch, and is bloomed from top branch；Flower
Powder is then also referred to as " cicada fungus conidia powder " for milk yellow, is exactly briefly " seed ", and pollen has breeding function.Cicada fungus worm
Grass forming process be：The larva of cicada is infected and parasitic before cicada sprouts wings by Cordyceps Militaris, when climatic environment is suitable, Cordyceps Militaris
The nutrition for absorbing polypide changes into mycelium, and final polypide accounts for tool by mycelium and only remains next body completely；When all things on earth is multiple
Su Shijie, mycelium gradates " the cicada fungus conidia powder " for having breeding function for the perfect stage from the vegetative phase again, gradually from top
Hold branch " germination " to be similar to flower, be also therefore referred to as cicada fungus.
Existing result of study shows that Periostracum cicadae, which has, to be improved immunity, improves renal function, antifatigue, reducing blood lipid, drop blood
The effects such as sugar, hypotensive, antitumor, improving eyesight, improvement sleep, radioresistance, analgesia, calmness.And the research of active ingredient is also indicated that,
The effective ingredient of Periostracum cicadae has cordycepin, Cordyceps sinensis polysaccharide, cordycepic acid etc., and the aminoacid ingredient in cicada fungus and a variety of cordyceps sinensis
In amino acid classes it is similar, with different degrees of benefiting action.Meanwhile, Periostracum cicadae also contains a variety of nutriments, such as
The polysaccharide of extraction is referred to as paecilomyces cicadae polysaccharide or Periostracum cicadae polysaccharide, has adjustment effect, to big to senile rat immunologic function
The tool such as mouse immunologic function and blood biochemical function has certain effect.It can be seen that, Periostracum cicadae be a kind of nutrition and health care value compared with
High integration of drinking and medicinal herbs product.But so far, the also rarely seen health product using Periostracum cicadae as main component of in the market, even
Some are known as the product of addition Periostracum cicadae health-care efficacy, and its processing to Periostracum cicadae is general also more simple and directly, very
The difficult drug effect for playing Periostracum cicadae to greatest extent.
The content of the invention
Therefore, the technical problems to be solved by the invention are to provide a kind of Periostracum cicadae instant powder, and further disclose
Its preparation method.
In order to solve the above technical problems, a kind of method for extracting Periostracum cicadae active ingredient of the present invention, including such as
Lower step：
(1) crushing that adds water of Periostracum cicadae coremium is taken to obtain slurries, and by gained slurries emulsification treatment, it is super through homogeneous after
Crushing of Ultrafine, obtains feed liquid；
(2) enzyme preparation is added into the feed liquid after above-mentioned processing and carries out enzymolysis processing；The enzyme preparation be selected from alpha-amylase,
At least one of beta amylase, cellulase, hemicellulase, trypsase, pectase；
(3) take the enzymolysis liquid after above-mentioned processing to carry out separation of solid and liquid, filtrate and residue are collected respectively；
(4) take above-mentioned filtrate to be handled through ceramic membrane filter, collect film process clear liquid, as containing required Periostracum cicadae effectively into
The extract solution divided.
In the step (1), the addition of the water is 5-8 times of the Periostracum cicadae coremium weight.
In the step (1), the emulsifying step is carried out in high-shearing dispersion emulsifying machine, and the homogenizing step is in high pressure
Carried out in high-shear homogenizing machine.
In the step (2), the addition of the enzyme preparation accounts for the 1-2wt% of the feed liquid weight.
In the step (3), in addition to the step of by the residue extracting in water of collection, and gained Aqueous extracts are added into fiber
Plain enzyme and/or hemicellulase continue enzymolysis processing, gained enzymolysis liquid are collected after separation of solid and liquid, by gained filtrate and step
(3) filtrate collected in merges.
In the step (3), the extracting in water step is ultrasonic extraction, and the ultrasonic power is 2000-3000W, shake
Plate frequency 100-150khz, Extracting temperature is 40-60 DEG C.
The present invention is also also disclosed extracts obtained Periostracum cicadae effective extract by described extracting method.
The present invention also also discloses the purposes that described Periostracum cicadae effective extract is used to prepare Periostracum cicadae instant powder.
The present invention also also discloses a kind of Periostracum cicadae instant powder, using described Periostracum cicadae effective extract as raw material,
Add customary adjuvant, be made according to common process.
The present invention also also discloses a kind of method for preparing described Periostracum cicadae instant powder, i.e., including containing required to described
Maltodextrin auxiliary material is added in the extract solution of Periostracum cicadae active ingredient and the step of through high-pressure homogeneous processing, subsequent spray is dried
Dry powder is obtained, and little particle is obtained through further boiling granulating, packaging is produced.
Instant powder is made using common process using Periostracum cicadae as primary raw material in Periostracum cicadae instant powder of the present invention,
Body immunity can be effectively improved, with improve sleep, it is antifatigue the effects such as, obtained instant powder can be directly used for taking,
Also the raw material that medicine, health food etc. can be acted on is utilized.
The method of the present invention for preparing instant powder, enzymolysis and extraction is entered using conbined enzymolysis to the Periostracum cicadae, can
The utilization rate of Periostracum cicadae is reached more than 90%, and after complex enzyme formulation extraction process, can preferably absorb.
In the method for enzymolysis Periostracum cicadae of the present invention, gained feed liquid is carried out at emulsification with high-shearing dispersion emulsifying machine
Reason, high tangential velocity and the powerful kinetic energy that brings of high frequency mechanical effect produced by being rotated at a high speed using rotor, make material it is fixed,
By strong machinery and aquashear in the narrow gap of rotor, by centrifuging extruding, liquid layer friction, hitting tear and turbulent flow
Deng comprehensive function, so that immiscible solid phase moment uniformly crushes, more subtly dispersion and emulsion, past by the circulation of high frequency
Multiple, the high-quality ultramicro grinding product stablized is more beneficial for the absorption of Periostracum cicadae.
Embodiment
The Periostracum cicadae extracts active ingredients of embodiment 1
The extraction of Periostracum cicadae active ingredient, comprises the following steps described in the present embodiment：
(1) Periostracum cicadae fresh sporophore 1kg is taken, it is broken through blade type beating crusher, add water when broken, add water total amount
For 5 times (5kg) of Periostracum cicadae fresh sporophore weight, obtained slurries are handled by high-shear emulsion machine, and mulser turns
Fast 5000rpm, the feed liquid handled through mulser further carries out ultramicro grinding, homogenizer work pressure through high pressure high-shear homogenizing machine
Power 95-100mpa, handles 5 repetitions；
(2) the treated feed liquid of step of learning from else's experience (1), adds the enzyme preparation (alpha-amylase for accounting for the feed liquid weight 1wt%：
Pectase=1：1), in carrying out enzymolysis processing under normal temperature；
(3) enzymolysis liquid for taking step (2) treated is centrifuged through tube centrifuge, collects filtrate and residue；Take
Filter residue adds the water that 5 times of quality are measured again, is extracted using sound-insulating supersonic extractors, control extractor power 2500W, shake plate
50 DEG C of frequency 120khz, Extracting temperature, carries out extraction 3min；Collect Aqueous extracts and add and account for the Aqueous extracts weight 2wt%'s
Cellulase continues enzymolysis processing, and after collection gained enzymolysis liquid is centrifuged, gained filtrate and the filtrate collected before are closed
And；
(4) gained filtrate is passed through to the ceramic membrane filter clarifying treatment in 0.1um apertures, film process clear liquid is collected, as contains
The extract solution of required Periostracum cicadae active ingredient.
The Periostracum cicadae extracts active ingredients of embodiment 2
The extraction of Periostracum cicadae active ingredient, comprises the following steps described in the present embodiment：
(1) Periostracum cicadae fresh sporophore 1kg is taken, it is broken through blade type beating crusher, add water when broken, add water total amount
For 8 times (8kg) of Periostracum cicadae fresh sporophore weight, obtained slurries are handled by high-shear emulsion machine, and mulser turns
Fast 5000rpm, the feed liquid handled through mulser further carries out ultramicro grinding, homogenizer work pressure through high pressure high-shear homogenizing machine
Power 95-100mpa, handles 5 repetitions；
(2) the treated feed liquid of step of learning from else's experience (1), adds the enzyme preparation (cellulase for accounting for the feed liquid weight 2wt%：
Trypsase=1：1), in carrying out enzymolysis processing under normal temperature；
(3) enzymolysis liquid for taking step (2) treated is centrifuged through tube centrifuge, collects filtrate and residue；Take
Filter residue adds the water that 5 times of quality are measured again, is extracted using sound-insulating supersonic extractors, control extractor power 2000W, shake plate
40 DEG C of frequency 100khz, Extracting temperature, carries out extraction 3min；Collect Aqueous extracts and add and account for the Aqueous extracts weight 2wt%'s
Cellulase continues enzymolysis processing, and after collection gained enzymolysis liquid is centrifuged, gained filtrate and the filtrate collected before are closed
And；
(4) gained filtrate is passed through to the ceramic membrane filter clarifying treatment in 0.1um apertures, film process clear liquid is collected, as contains
The extract solution of required Periostracum cicadae active ingredient.
The Periostracum cicadae extracts active ingredients of embodiment 3
The extraction of Periostracum cicadae active ingredient, comprises the following steps described in the present embodiment：
(1) Periostracum cicadae fresh sporophore 1kg is taken, it is broken through blade type beating crusher, add water when broken, add water total amount
For 6 times (6kg) of Periostracum cicadae fresh sporophore weight, obtained slurries are handled by high-shear emulsion machine, and mulser turns
Fast 5000rpm, the feed liquid handled through mulser further carries out ultramicro grinding, homogenizer work pressure through high pressure high-shear homogenizing machine
Power 95-100mpa, handles 5 repetitions；
(2) the treated feed liquid of step of learning from else's experience (1), adds the enzyme preparation (β-starch for accounting for the feed liquid weight 1.5wt%
Enzyme), in carrying out enzymolysis processing under normal temperature；
(3) enzymolysis liquid for taking step (2) treated is centrifuged through tube centrifuge, collects filtrate and residue；Take
Filter residue adds the water that 5 times of quality are measured again, is extracted using sound-insulating supersonic extractors, control extractor power 3000W, shake plate
60 DEG C of frequency 150khz, Extracting temperature, carries out extraction 3min；Collect Aqueous extracts and add and account for the Aqueous extracts weight 2wt%'s
Hemicellulase continues enzymolysis processing, after collection gained enzymolysis liquid is centrifuged, by gained filtrate and the filtrate collected before
Merge；
(4) gained filtrate is passed through to the ceramic membrane filter clarifying treatment in 0.1um apertures, film process clear liquid is collected, as contains
The extract solution of required Periostracum cicadae active ingredient.
The Periostracum cicadae extracts active ingredients of embodiment 4
The extraction of Periostracum cicadae active ingredient, comprises the following steps described in the present embodiment：
(1) Periostracum cicadae fresh sporophore 1kg is taken, it is broken through blade type beating crusher, add water when broken, add water total amount
For 7 times (7kg) of Periostracum cicadae fresh sporophore weight, obtained slurries are handled by high-shear emulsion machine, and mulser turns
Fast 5000rpm, the feed liquid handled through mulser further carries out ultramicro grinding, homogenizer work pressure through high pressure high-shear homogenizing machine
Power 95-100mpa, handles 5 repetitions；
(2) the treated feed liquid of step of learning from else's experience (1), adds the enzyme preparation (cellulose for accounting for the feed liquid weight 1.5wt%
Enzyme：Hemicellulase=1：1), in carrying out enzymolysis processing under normal temperature；
(3) enzymolysis liquid for taking step (2) treated is centrifuged through tube centrifuge, collects filtrate and residue；Take
Filter residue adds the water that 5 times of quality are measured again, is extracted using sound-insulating supersonic extractors, control extractor power 3000W, shake plate
60 DEG C of frequency 150khz, Extracting temperature, carries out extraction 3min；Collect Aqueous extracts and add and account for the Aqueous extracts weight 2wt%'s
Hemicellulase continues enzymolysis processing, after collection gained enzymolysis liquid is centrifuged, by gained filtrate and the filtrate collected before
Merge；
(4) gained filtrate is passed through to the ceramic membrane filter clarifying treatment in 0.1um apertures, film process clear liquid is collected, as contains
The extract solution of required Periostracum cicadae active ingredient.
The Periostracum cicadae extracts active ingredients of embodiment 5
The extraction of Periostracum cicadae active ingredient, comprises the following steps described in the present embodiment：
(1) Periostracum cicadae fresh sporophore 1kg is taken, it is broken through blade type beating crusher, add water when broken, add water total amount
For 6.5 times (6.5kg) of Periostracum cicadae fresh sporophore weight, obtained slurries are handled by high-shear emulsion machine, emulsification
Machine rotating speed 5000rpm, the feed liquid handled through mulser further carries out ultramicro grinding, homogenizer work through high pressure high-shear homogenizing machine
Make pressure 95-100mpa, handle 5 repetitions；
(2) the treated feed liquid of step of learning from else's experience (1), adds the enzyme preparation (cellulose for accounting for the feed liquid weight 1.5wt%
Enzyme：Pectase=1：1), in carrying out enzymolysis processing under normal temperature；
(3) enzymolysis liquid for taking step (2) treated is centrifuged through tube centrifuge, collects filtrate and residue；Take
Filter residue adds the water that 5 times of quality are measured again, is extracted using sound-insulating supersonic extractors, control extractor power 3000W, shake plate
60 DEG C of frequency 150khz, Extracting temperature, carries out extraction 3min；Collect Aqueous extracts and add and account for the Aqueous extracts weight 2wt%'s
Hemicellulase continues enzymolysis processing, after collection gained enzymolysis liquid is centrifuged, by gained filtrate and the filtrate collected before
Merge；
(4) gained filtrate is passed through to the ceramic membrane filter clarifying treatment in 0.1um apertures, film process clear liquid is collected, as contains
The extract solution of required Periostracum cicadae active ingredient.
The Periostracum cicadae instant powder of embodiment 6
The preparation of Periostracum cicadae instant powder includes described in the present embodiment：It is obtained effective containing Periostracum cicadae in Example 1
The extract solution of composition, maltodextrin (DE8-10) is added according to the ratio of the Periostracum cicadae fresh sporophore heavy amount 10% of addition,
It is spray-dried to obtain dry powder after being come out after mixing through high pressure homogenizer homogeneous, and after further boiling granulating, what is obtained is small
Particle, packaging.
The Periostracum cicadae instant powder of embodiment 7
The preparation of Periostracum cicadae instant powder includes described in the present embodiment：It is obtained effective containing Periostracum cicadae in Example 2
The extract solution of composition, maltodextrin (DE8-10) is added according to the ratio of the Periostracum cicadae fresh sporophore heavy amount 10% of addition,
It is spray-dried to obtain dry powder after being come out after mixing through high pressure homogenizer homogeneous, and after further boiling granulating, what is obtained is small
Particle, packaging.
The Periostracum cicadae instant powder of embodiment 8
The preparation of Periostracum cicadae instant powder includes described in the present embodiment：It is obtained effective containing Periostracum cicadae in Example 3
The extract solution of composition, maltodextrin (DE8-10) is added according to the ratio of the Periostracum cicadae fresh sporophore heavy amount 10% of addition,
It is spray-dried to obtain dry powder after being come out after mixing through high pressure homogenizer homogeneous, and after further boiling granulating, what is obtained is small
Particle, packaging.
The Periostracum cicadae instant powder of embodiment 9
The preparation of Periostracum cicadae instant powder includes described in the present embodiment：It is obtained effective containing Periostracum cicadae in Example 4
The extract solution of composition, maltodextrin (DE8-10) is added according to the ratio of the Periostracum cicadae fresh sporophore heavy amount 10% of addition,
It is spray-dried to obtain dry powder after being come out after mixing through high pressure homogenizer homogeneous, and after further boiling granulating, what is obtained is small
Particle, packaging.
The Periostracum cicadae instant powder of embodiment 10
The preparation of Periostracum cicadae instant powder includes described in the present embodiment：It is obtained effective containing Periostracum cicadae in Example 5
The extract solution of composition, maltodextrin (DE8-10) is added according to the ratio of the Periostracum cicadae fresh sporophore heavy amount 10% of addition,
It is spray-dried to obtain dry powder after being come out after mixing through high pressure homogenizer homogeneous, and after further boiling granulating, what is obtained is small
Particle, packaging.
Experimental example
Its advantage is verified with Periostracum cicadae instant powder obtained by the embodiment of the present invention 8,300 different age groups are chosen
Crowd take, wherein each half of men and women, the age is averaged from 20-60 Sui age bracket number.It is early, middle and late for each person every day respectively to take
50g, bath 150mL takes.
After 15 days, 1/3rd groups of people feel condition on probation substantially improves, and fatigue state has clear improvement, and sleeps
Dormancy state improves；It is most of substantially to feel above-mentioned improvement per capita after 1 month；Take at the latest two months, all people on probation
Member can substantially experience above-mentioned change.It can be seen that, Periostracum cicadae oral liquid of the present invention can effectively improve body immunity, tool
Have improvement sleep, it is antifatigue the effects such as.
Obviously, above-described embodiment is only intended to clearly illustrate example, and the not restriction to embodiment.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of change or
Change.There is no necessity and possibility to exhaust all the enbodiments.And the obvious change thus extended out or
Among changing still in the protection domain of the invention.
Claims (10)
1. a kind of method for extracting Periostracum cicadae active ingredient, it is characterised in that comprise the following steps：
(1) crushing that adds water of Periostracum cicadae coremium is taken to obtain slurries, and by gained slurries emulsification treatment, through homogeneous Ultramicro-powder after
It is broken, obtain feed liquid；
(2) enzyme preparation is added into the feed liquid after above-mentioned processing and carries out enzymolysis processing；The enzyme preparation is selected from alpha-amylase, β-shallow lake
At least one of powder enzyme, cellulase, hemicellulase, trypsase, pectase；
(3) take the enzymolysis liquid after above-mentioned processing to carry out separation of solid and liquid, filtrate and residue are collected respectively；
(4) take above-mentioned filtrate to be handled through ceramic membrane filter, film process clear liquid is collected, as containing required Periostracum cicadae active ingredient
Extract solution.
2. the method according to claim 1 for extracting Periostracum cicadae active ingredient, it is characterised in that in the step (1),
The addition of the water is 5-8 times of the Periostracum cicadae coremium weight.
3. the method according to claim 1 or 2 for extracting Periostracum cicadae active ingredient, it is characterised in that the step (1)
In, the emulsifying step is carried out in high-shearing dispersion emulsifying machine, and the homogenizing step is carried out in high pressure high-shear homogenizing machine.
4. the method for the extraction Periostracum cicadae active ingredient according to claim any one of 1-3, it is characterised in that the step
Suddenly in (2), the addition of the enzyme preparation accounts for the 1-2wt% of the feed liquid weight.
5. the method for the extraction Periostracum cicadae active ingredient according to claim any one of 1-4, it is characterised in that the step
Suddenly in (3), in addition to the step of by the residue extracting in water of collection, and gained Aqueous extracts are added into cellulase and/or half fine
The plain enzyme of dimension continues enzymolysis processing, collects gained enzymolysis liquid after separation of solid and liquid, the filtrate that will be collected in gained filtrate and step (3)
Merge.
6. the method according to claim 5 for extracting Periostracum cicadae active ingredient, it is characterised in that in the step (3),
The extracting in water step is ultrasonic extraction, and the ultrasonic power is 2000-3000W, shake plate frequency 100-150khz, extracts temperature
Spend for 40-60 DEG C.
7. obtained Periostracum cicadae effective extract is extracted as the extracting method described in claim any one of 1-6.
8. the Periostracum cicadae effective extract described in claim 7 is used for the purposes for preparing Periostracum cicadae instant powder.
9. a kind of Periostracum cicadae instant powder, it is characterised in that using the Periostracum cicadae effective extract described in claim 7 as original
Material, adds customary adjuvant, is made according to common process.
10. a kind of method of the Periostracum cicadae instant powder prepared described in claim 9, it is characterised in that including containing institute to described
Need to add maltodextrin auxiliary material in the extract solution of Periostracum cicadae active ingredient and the step of through high-pressure homogeneous processing, subsequent spray is done
It is dry to obtain dry powder, and little particle is obtained through further boiling granulating, packaging is produced.
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| CN110791497B (en) * | 2019-11-06 | 2022-04-29 | 江苏医药职业学院 | Enzyme composition and preparation method thereof |
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Application publication date: 20170922 |