CN107182804A

CN107182804A - A kind of GMP workshops animal feeding room drainage technological design

Info

Publication number: CN107182804A
Application number: CN201710615082.4A
Authority: CN
Inventors: 贾布托; 贾志平; 余彬辉
Original assignee: Zhejiang Yi Jian Biological Products Co Ltd
Current assignee: Zhejiang Yi Jian Biological Products Co Ltd
Priority date: 2017-07-26
Filing date: 2017-07-26
Publication date: 2017-09-22

Abstract

The animal feeding room drainage technological design of GMP workshops is based on the invention discloses one kind, it is mainly used in the big or middle animal feeding room dirt separation discharge in GMP workshops, it is characterized in that small opening cover plate, a section dirt are slipped through the net and the design of fluid-tight airflow partition, wherein, the small opening deck design, for solving system first separation function；Described section of dirt is slipped through the net design, for solving the problems, such as secondary separation；The fluid-tight airflow partition design, for solving, room pressure difference during blowdown is constant and blow-off pipe pours in down a chimney problem.

Description

GMP workshop animal feeding room drainage system process design

Technical Field

The invention belongs to the technical field of biological medicines, and particularly relates to a sewage separation and discharge system for large and medium animal raising rooms in a GMP workshop.

Background

Under the encouragement of national policy, domestic biopharmaceutical enterprises are increasing day by day, along with the demand and quality requirements of the market on products, the GMP production workshop needs to guarantee the production quantity all the year round, the quality also needs to be guaranteed, the function of an animal house is inspected, namely, the animal test is carried out on the finished vaccine, the biological safety of the product is confirmed, the design and acceptance of the animal house are inspected, the laws and regulations are strictly executed, and meanwhile, the design and acceptance of the animal house are also restricted by a plurality of industrial standards, the daily animal raising excrement is generally a solid-liquid mixture, the viscosity is high, the discharge difficulty is high, certain pressure is caused on a sewage discharge pipeline, partial sewage after security inspection can also relate to the biological safety hidden trouble carrying active substances, special treatment is required, the sewage discharge of the large and medium animal raising rooms of the domestic biopharmaceutical enterprises at present is designed to be a drainage ditch type branched summary filtration drainage, or a front-end straight-through, the design easily causes that sewage pipes are frequently blocked or air flows in rooms leak through sewage discharge facilities when sewage is discharged, so that the later-stage operation cost and the maintenance rate of the sewage discharge pipes are greatly improved, and the most important is that the normal maintenance of the pressure difference of adjacent rooms is difficult to ensure. The design scheme of the invention solves the problems, thoroughly avoids the pressure difference fluctuation of adjacent rooms under the condition of ensuring the normal sewage discharge of the animal feeding room, designs the secondary separation device at the front end of the sewage discharge, can avoid the maintenance problems of frequent blockage of a sewage discharge system and the like through daily cleaning, and can also reduce the problem of pipe fitting blockage of a rear-section sewage inactivation system.

Disclosure of Invention

Aiming at the defects of the prior GMP workshop animal feeding room sewage discharge system process design, the invention provides a matched device which ensures solid-liquid interception and separation, liquid seal pressure maintaining and operation and maintenance of the whole system through a leak hole cover plate, a sewage interception and leakage net, a liquid seal partition air flow design and the like.

The purpose of the invention is realized by the following technical scheme: a GMP-based workshop animal feeding room blowdown system process design is characterized by comprising the following contents:

the design of a leak hole cover plate, the design of a sewage interception leak net and the design of a liquid seal partition airflow; wherein,

the design of the leak hole cover plate is as follows:

the method comprises the following steps: the sewage in the animal feeding chamber flows into a sewage discharge system through a leak hole cover plate and is separated for the first time;

the design of the sewage interception leakage net is as follows:

the method comprises the following steps: the sewage interception and leakage net in the sewage discharge system carries out secondary separation on the sewage which flows in from the primary separation;

step two: after secondary separation by the sewage interception and leakage net, the sewage in the sewage system flows into the partition area of the sewage pipe through the sewage baffle plate;

step three: the liquid levels of the left and right chambers of the sewage draining partition board are flush and are always higher than the lowest position of the partition of the sewage draining board, so that the liquid sealing state of the sewage draining system is ensured;

the liquid seal cuts off the air current design:

the method comprises the following steps: the sewage discharge system is made of stainless steel and is arranged flush with the ground of the indoor drainage ditch;

step two: dividing the sewage system (box body) into two parts, and uniformly and fully welding three edges of the middle partition plate to the box body to form a sewage partition plate;

step three: the box body is injected with water quantitatively to form a liquid seal state, and the lower end of the partition plate is lower than the water surface for a certain position, so that the pressure of a sealed room can be cut off, and the problem of abnormal flow of air flow between rooms or between the room and a trench is solved;

compared with the prior art, the invention has the beneficial effects that:

1. a drain hole cover plate designed on the outermost surface of the animal raising room sewage discharge system can be used for roughly filtering sewage;

2. the unique sewage interception and leakage net design is used for carrying out secondary filtration on the sewage discharged into the sewage discharge system, so that large-particle objects can not flow through the leakage net, and the blockage caused by long-term accumulation of the sewage such as animal excrement and the like in the sewage discharge system is avoided;

3. the unique design of the sewage discharge partition plate and the sewage discharge vertical pipe ensures constant liquid in the sewage discharge system and liquid seal of the liquid;

4. the blowdown system maintenance apron adopts full welding mode, has guaranteed the leakproofness of blowdown system, and during later stage blowdown pipeline maintenance, can directly realize through the blowdown apron, and need not to carry out the operation of ground ditching.

Drawings

FIG. 1 is a front view

FIG. 2 top view

FIG. 3 is a side view (left view)

FIG. 4 is a side view (Right side view)

In the figure: a is a leak hole cover plate, B is a sewage interception leak net, C is a sewage discharge partition plate, D is a sewage discharge vertical pipe, E is a leak hole cover plate fixing block, F is a sewage interception leak net fixing block, and G is a sewage discharge box body.

Detailed Description

The operation mode is as follows:

1. the dirt in the animal raising room flows into the A in a cleaning mode;

2. the dirt is subjected to solid-liquid separation through the B, and the liquid flows into the partition area of the D through the C;

3. the liquid level in the sewage discharge system is always higher than the lowest end of the C, and when the liquid level is higher than the upper surface of the D, sewage discharge is carried out;

4. when the liquid level in the sewage discharge system is discharged to be lower than the upper surface of D, stopping discharging sewage, and repeating the steps;

cleaning mode:

1. the liquid level in the sewage draining groove is ensured to be always higher than the lowest end of the C;

2. manually lifting the A, lifting the B out of the sewage draining groove, and removing the dirt trapped in the B;

3. b, cleaning and cleaning the trapped matter in the B, putting the cleaned trapped matter into a sewage system again, resetting the A, and entering an operation mode;

and (3) maintenance mode:

1. cleaning a sewage system, and soaking the sewage system in disinfection water;

2. carrying out ozone or formaldehyde fumigation in a room;

3. removing A, B, cutting G, and removing C;

4. cleaning and maintaining the sewage draining tank;

5. after maintenance, G is welded and B, A is reset and installed.

Claims

1. A GMP workshop animal feeding room based blowdown system process design is characterized in that a leakage hole cover plate, a sewage interception leakage net and a liquid seal partition air flow design are adopted, wherein the leakage hole cover plate is designed to solve the problem of a system primary separation function; the sewage interception leakage net is designed to solve the problem of secondary separation; the liquid seal partition airflow design is used for solving the problems of constant room pressure difference and backflow of a sewage discharge pipe during sewage discharge.

2. The GMP plant animal feeding room exhaust system process design according to claim 1, wherein the orifice cover design comprises:

the leak hole cover plate is used for separating sewage once, is made of stainless steel, and can change in size according to the sewage discharge amount.

3. The GMP plant animal feeding room exhaust system process design according to claim 1, wherein the drain trap design comprises:

the sewage interception leakage net is used for secondary separation of sewage, is made of stainless steel, and can change size according to the sewage discharge amount.

4. The GMP plant animal feeding room exhaust system process design according to claim 1, wherein the liquid seal off air flow design comprises:

the sewage discharge partition plate is designed for partially partitioning the sewage discharge groove to form a U-shaped liquid seal groove, the stainless steel material is adopted, the connection mode is selected for welding, and the size can be changed according to the sewage discharge amount;

the design of blowdown box for blowdown groove later maintenance adopts stainless steel, and the connected mode selects the welding, and the size can change according to the blowdown volume.

5. A method of operating a GMP-based process design for animal husbandry room exhaust system according to claim 1, comprising the steps of:

step 1: the sewage draining tank is in a liquid sealing state;

step 2: the sewage in the animal feeding chamber flows into the sewage discharge groove after being separated for one time through the leak hole cover plate;

and step 3: the sewage blocking and leaking net in the sewage draining groove carries out secondary separation on the sewage after primary separation;

and 4, step 4: when the liquid level in the sewage discharge groove exceeds the opening of the sewage discharge pipe, the liquid is quantitatively discharged to the leveling position of the opening of the sewage discharge pipe.