CN107157824A - A kind of antioxidant composition and cosmetics and application - Google Patents

A kind of antioxidant composition and cosmetics and application Download PDF

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Publication number
CN107157824A
CN107157824A CN201710318601.0A CN201710318601A CN107157824A CN 107157824 A CN107157824 A CN 107157824A CN 201710318601 A CN201710318601 A CN 201710318601A CN 107157824 A CN107157824 A CN 107157824A
Authority
CN
China
Prior art keywords
mass parts
cosmetics
tomato
flos micheliae
micheliae albae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710318601.0A
Other languages
Chinese (zh)
Inventor
葛啸虎
陈海佳
王飞
王一飞
张凤端
王小燕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Saliai Stemcell Science and Technology Co Ltd
Original Assignee
Guangzhou Saliai Stemcell Science and Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Saliai Stemcell Science and Technology Co Ltd filed Critical Guangzhou Saliai Stemcell Science and Technology Co Ltd
Priority to CN201710318601.0A priority Critical patent/CN107157824A/en
Publication of CN107157824A publication Critical patent/CN107157824A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/96Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toilet preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use

Abstract

The invention discloses a kind of antioxidant composition and cosmetics and application.The antioxidant composition, including tomato antioxygen element and Flos micheliae Albae extract, wherein plain 0.2 3 mass parts of tomato antioxygen, the mass parts of Flos micheliae Albae extract 0.5 5.Antioxidant composition of the present invention is using tomato antioxygen element and Flos micheliae Albae extract as main active, by the way that tomato antioxygen element and Flos micheliae Albae extract are compounded in the ratio of restriction, resulting composition and cosmetics have good antioxidant effect, tomato antioxygen element can give full play to the effect of its antioxidation activity under the ratio of the present invention, be acted synergistically with Flos micheliae Albae extract.

Description

A kind of antioxidant composition and cosmetics and application
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of antioxidant composition and cosmetics and application.
Background technology
Anti-aging is the wonderful dream that people pursue always from ancient times to the present, but with advancing age, human body naturally resists The ability of free radical (i.e. anti-oxidant) constantly declines, and skin can be roughening, produces wrinkle and pigmentation.
The approach of anti-aging cosmetics anti-aging in the market is concentrated mainly on three big aspects:(1) remove Excessive active oxygen radical;(2) metabolism of cell is promoted;(3) collagen and elastin laminin in supplement skin.Its Moderate resistance free radical theory theory has obtained extensive approval in the industry:Intracellular free radicals are removed mainly by antioxidation, Every polyphenoils can be described as free radical scavenger.
In common antioxidation cosmetic product to contain vitamins, the vitamin used is all synthetic vitamin, with people more Health perception enhancing, artificial synthesized antioxidant is bad because of its normal self stability, easily changes colour spoiled, anti-oxidant effect Fruit can not allow consumer satisfaction, and increasingly be out of favour.On the contrary, being obtained from natural products with certain antioxidation activity Material is increasingly taken seriously.Especially many researchs confirm that many Natural Antioxidants can suppress inside of human body in recent years Lipid peroxidization, have positive prevention effect to anti-aging.
The content of the invention
It is an object of the invention to overcoming the defect of prior art there is provided a kind of antioxidant composition of natural origin and Cosmetics and application.
In order to solve the above technical problems, the present invention is adopted the following technical scheme that:
A kind of antioxidant composition, including tomato antioxygen element and Flos micheliae Albae extract, wherein tomato antioxygen element 0.2-3 mass Part, Flos micheliae Albae extract 0.5-5 mass parts.
Preferably, the antioxidant composition includes following components of following mass parts:Tomato antioxygen element 1-2 mass parts, Flos micheliae Albae extract 2-5 mass parts.
Preferably, the antioxidant composition is made up of following components of following mass parts:Tomato antioxygen 1.5 mass of element Part, the mass parts of Flos micheliae Albae extract 5.
In antioxidant composition of the present invention tomato antioxygen element containing abundant lycopene, carotenoid, phytosterol, Tocopherol, with superpower oxidation resistance, keeps young skin here and takees good care of the All Pure Nature mode of itself;Flos micheliae Albae extract has Good anti-oxidant, antiradical activities, protection and reparation skin, improve skin.
In above-mentioned antioxidant composition, the tomato antioxygen element is Italian AKOTT product, the entitled Tomato Seed of INCI Oil, containing abundant lycopene, carotenoid, phytosterol, tocopherol, with superpower oxidation resistance.Wherein tomato Red pigment is the most strong antioxidant found in the world at present, is referred to as " plant gold " by western countries.Lycopene is removed certainly Other carotenoid and vitamin E, vitamin C are outclassed by effect of base, its oxidation resistance is 100 times of vitamin E, Ascorbic 1,000 times, skin resistance oxidation radiation can be helped, free radical is removed.
In above-mentioned antioxidant composition, the Flos micheliae Albae extract is the product of EUROCOSTECH companies of South Korea, INCI Entitled water, butanediol, orchid extract solution.Flos micheliae Albae is South Korea's national flower, most perfect natural plants, rich in mineral matter, to skin Good penetrability, cutaneous immunisation power can be improved.
A kind of cosmetics, conventional matrix and/or deionization comprising above-mentioned antioxidant composition and cosmetics exterior-applied formulation Water.
Preferably, the toiletry bag contains following components of following mass parts:
Tomato antioxygen element 0.2-3 mass parts, Flos micheliae Albae extract 0.5-5 mass parts, the conventional base of cosmetics exterior-applied formulation Matter and/or deionized water 92-99.3 mass parts.
Preferably, the toiletry bag contains following components of following mass parts:Tomato antioxygen element 1-2 mass parts, Flos micheliae Albae Extract 2-5 mass parts, the conventional matrix and/or deionized water of cosmetics exterior-applied formulation are 93-97 mass parts.
Preferably, the toiletry bag contains following components of following mass parts:Tomato antioxygen 1.5 mass parts of element, Flos micheliae Albae The mass parts of extract 5, the conventional matrix and/or deionized water of cosmetics exterior-applied formulation are 93.5 mass parts.
The formulation of cosmetics of the present invention, which is preferably that cream shape, emulsion form or elite honey etc. are a variety of, to be accepted Dosage form.
The conventional matrix of the cosmetics exterior-applied formulation includes emulsifying agent, grease, emollient, NMF, thickener, polynary One or more in alcohol, preservative and essence.
Application of the antioxidant composition in cosmetics are prepared.
Compared with prior art, the present invention has the advantages that:Antioxidant composition of the present invention is with tomato antioxygen element It is main active with Flos micheliae Albae extract, by the way that tomato antioxygen element and Flos micheliae Albae extract are answered in the ratio limited Match somebody with somebody, resulting composition and cosmetics have good antioxidant effect, tomato antioxygen element can fully be sent out under the ratio of the present invention The effect of its antioxidation activity is waved, is acted synergistically with Flos micheliae Albae extract.
Brief description of the drawings
Fig. 1 is DPPH clearance rates in embodiment 7.
Embodiment
The antioxidant composition and cosmetics that the present invention is provided using tomato antioxygen element and Flos micheliae Albae extract as primary raw material, Add cosmetic composition and often use matrix components emulsifying agent, grease, emollient, NMF, thickener, polyalcohol, preservative, perfume (or spice) One or more in essence and deionized water etc. are made.
Embodiment 1, anti-oxidant elite honey
The anti-oxidant elite honey of the present embodiment of every 100 mass parts, is made up of following components by following mass parts:
Aqueous phase:Deionized water surplus, the mass parts of carbomer 0.1, the mass parts of glycerine 3, the mass parts of butanediol 4, polysorbate The mass parts of ester -601, the mass parts of trehalose 2.
Oil phase:The mass parts of PAA/sodium acryloyldimethyl taurate copolymers 0.6, ring five dimethyl silicone polymer 3 Mass parts, tomato antioxygen 0.2 mass parts of element.
Oil phase and aqueous phase are heated separately to after 80 DEG C, after several minutes of two-phase mixtures homogeneous, stirring cooling is cooled to 45 DEG C Add the mass parts of triethanolamine 0.1 to neutralize, stir, add the mass parts of Flos micheliae Albae extract 0.5, appropriate amount of essence and anti-corrosion Agent stirs, and continues to be cooled to 35 DEG C of dischargings that stir.
Embodiment 2, anti-oxidant emulsion
The anti-oxidant emulsion of the present embodiment of every 100 mass parts, is made up of following components by following mass parts:
Aqueous phase:Deionized water surplus, the mass parts of xanthans 0.1, the mass parts of glycerine 3, the mass parts of butanediol 4, the matter of trehalose 2 Measure part.
Oil phase:The mass parts of C12-20 alkyl glucosides 2, the mass parts of stearine 1.5, the matter of cetearyl alcohol acid esters 0.8 Measure part, the mass parts of caprylic/capric triglyceride 4, the mass parts of White Mineral Oil 3, the mass parts of dimethyl silicone polymer 2, tomato antioxygen element 0.5 mass parts.
Oil phase and aqueous phase are heated separately to after 80 DEG C, after several minutes of two-phase mixtures homogeneous, stirring cooling is cooled to 45 DEG C Add the mass parts of Flos micheliae Albae extract 1.5, appropriate amount of essence and preservative to stir, continue to be cooled to 35 DEG C stirring out Material.
Embodiment 3, anti-oxidant emulsion
The anti-oxidant emulsion of the present embodiment of every 100 mass parts, is made up of following components by following mass parts:
Aqueous phase:Deionized water surplus, the mass parts of xanthans 0.1, the mass parts of glycerine 3, the mass parts of butanediol 4, the matter of trehalose 2 Measure part.
Oil phase:The mass parts of C12-20 alkyl glucosides 2, the mass parts of stearine 1.5, the matter of cetearyl alcohol acid esters 0.8 Measure part, the mass parts of caprylic/capric triglyceride 4, the mass parts of White Mineral Oil 3, the mass parts of dimethyl silicone polymer 2, tomato antioxygen element 1 Mass parts.
Oil phase and aqueous phase are heated separately to after 80 DEG C, after several minutes of two-phase mixtures homogeneous, stirring cooling is cooled to 45 DEG C Add the mass parts of Flos micheliae Albae extract 3, appropriate amount of essence and preservative to stir, continue to be cooled to 35 DEG C of dischargings that stir.
Embodiment 4, anti-oxidant cream
The anti-oxidant cream of the present embodiment of every 100 mass parts, is made up of following components by following mass parts:
Aqueous phase:Deionized water surplus, the mass parts of xanthans 0.2, the mass parts of glycerine 5, the mass parts of butanediol 5, the matter of trehalose 2 Measure part.
Oil phase:The mass parts of C12-20 alkyl glucosides 1.5, the mass parts of stearine 0.8, ethylene glycol palmitate 2.2 mass parts, the mass parts of caprylic/capric triglyceride 5, the mass parts of White Mineral Oil 5, the mass parts of dimethyl silicone polymer 2, tomato resists Oxygen 3 mass parts of element.
Oil phase and aqueous phase are heated separately to after 80 DEG C, after several minutes of two-phase mixtures homogeneous, stirring cooling is cooled to 45 DEG C Add the mass parts of Flos micheliae Albae extract 4, appropriate amount of essence and preservative to stir, continue to be cooled to 35 DEG C of dischargings that stir.
Embodiment 5, anti-oxidant cream
The anti-oxidant cream of the present embodiment of every 100 mass parts, is made up of following components by following mass parts:
Aqueous phase:Deionized water surplus, the mass parts of xanthans 0.2, the mass parts of glycerine 5, the mass parts of butanediol 5, the matter of trehalose 2 Measure part.
Oil phase:The mass parts of C12-20 alkyl glucosides 1.5, the mass parts of stearine 0.8, ethylene glycol palmitate 2.2 mass parts, the mass parts of caprylic/capric triglyceride 5, the mass parts of White Mineral Oil 5, the mass parts of dimethyl silicone polymer 2, tomato resists Oxygen 1.5 mass parts of element.
Oil phase and aqueous phase are heated separately to after 80 DEG C, after several minutes of two-phase mixtures homogeneous, stirring cooling is cooled to 45 DEG C Add the mass parts of Flos micheliae Albae extract 5, appropriate amount of essence and preservative to stir, continue to be cooled to 35 DEG C of dischargings that stir.
The crease-resistant experiment of embodiment 6, human body skin
By the principle of voluntariness selection age in 29-56, the face of the main organs illness such as no severe cardiac, liver, kidney has substantially Wrinkle person is subject, totally 72, all women, average age 35 years old.It is randomly divided into 4 groups, every group of 18 people.Wherein 1 group makes The anti-aging cream prepared with the embodiment of the present invention 5 is as experimental group, and 3 groups are resisted using removing tomato in embodiment 5 respectively in addition The cream of oxygen element as a control group 1, remove the cream as a control group 2, and remove tomato antioxygen simultaneously of Flos micheliae Albae extract The cream as a control group 3 of element and Flos micheliae Albae extract, carries out observation of curative effect.
During experiment, take appropriate cream to be equably applied to face, smear once sooner or later daily, it is continuous to use 28 days, The relevant cosmetics of face are stopped using during experiment.Use front and rear contrast types of facial makeup in Beijing operas instrument test light lower face skin surface wrinkle rating (numerical value smaller represent wrinkle degree lighter).As a result it is as shown in table 1.
Table 1, each group cream use front and rear wrinkle rating (x ± SD, n=1)
Group Before use After use
Experimental group 8.36±8.79 5.68±8.07
Control group 1 8.48±8.73 6.02±8.32
Control group 2 8.67±8.67 6.68±8.28
Control group 3 8.43±8.56 7.14±8.22
As seen from the results in Table 1, control group is somewhat made moderate progress after using cream to wrinkle of skin, and experimental group is using cream Obvious to the improvement of wrinkle of skin before and after white, its effect for improving wrinkle of skin is substantially better than an addition tomato antioxygen element Control group 1, the only control group 2 of addition Flos micheliae Albae extract, the control group 3 without tomato antioxygen element and Flos micheliae Albae extract, Prove that tomato antioxygen element can give full play to the effect of its antioxidation activity under this ratio, and work is cooperateed with Flos micheliae Albae extract With the antioxidant effect of product is obviously improved.The antioxidant composition of tomato antioxygen element and Flos micheliae Albae extract composition is even Continue after using 28 days, have good improvement for the wrinkle on skin, there is anti-oxidant, anti-aging.
Embodiment 7, anti-oxidant experiment
DPPH methods determination sample removes the ability of free radical.Experimental group and control group set as follows:With the embodiment of the present invention 5 The anti-aging cream of preparation separately sets 4 groups of control groups, i.e., using the cream for removing tomato antioxygen element in embodiment 5 as experimental group As a control group 1, remove the cream as a control group 2, and remove tomato antioxygen element and Flos micheliae Albae simultaneously of Flos micheliae Albae extract The cream of extract as a control group 3, with 0.2mg/ml ascorbic acid as a control group 4.
Accurately weighed 0.05g experimental groups and control group cream, 10mL are settled to deionized water, concussion is uniformly dissolved, point Other compound concentration is the 0.2mg/mL aqueous solution.Reaction is complete in equal volume by sample and the 0.2mg/ml prepared with deionized water DPPH After 30min, final absorbance is recorded.Free radical scavenging activity (%)=[(sample adds the extinction of DPPH absorbance-sample to 1- Degree)/DPPH absorbance] × 100%.Experimental result is shown in accompanying drawing 1.
Experimental group sample and control sample play the role of necessarily to Green Tea Extract, with the 0.2mg/ml's of control group 4 Ascorbic acid is standard reference material, and the antioxidant effect of experimental group sample is substantially better than only addition tomato antioxygen element as shown in Figure 1 Control group 1, only addition Flos micheliae Albae extract control group 2, without tomato antioxygen element and Flos micheliae Albae extract control group 3, it was demonstrated that tomato antioxygen element can give full play to its effect for removing free radical under this ratio, be cooperateed with Flos micheliae Albae extract The antioxidant composition addition of effect, i.e. tomato antioxygen element and Flos micheliae Albae extract composition has anti-oxidant well in cosmetics Effect.
Embodiment described above only expresses the several embodiments of the present invention, and it describes more specific and detailed, but simultaneously Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (10)

1. a kind of antioxidant composition, it is characterised in that:Including tomato antioxygen element and Flos micheliae Albae extract, wherein tomato antioxygen element 0.2-3 mass parts, Flos micheliae Albae extract 0.5-5 mass parts.
2. antioxidant composition according to claim 1, it is characterised in that:Following components comprising following mass parts:Kind Eggplant antioxygen element 1-2 mass parts, Flos micheliae Albae extract 2-5 mass parts.
3. antioxidant composition according to claim 2, it is characterised in that:The antioxidant composition is by following mass parts Following components composition:Tomato antioxygen 1.5 mass parts of element, the mass parts of Flos micheliae Albae extract 5.
4. a kind of cosmetics, it is characterised in that:Comprising the antioxidant composition described in claim 1 and cosmetics exterior-applied formulation Conventional matrix and/or deionized water.
5. cosmetics according to claim 4, it is characterised in that:The toiletry bag contains following groups of following mass parts Point:Tomato antioxygen element 0.2-3 mass parts, Flos micheliae Albae extract 0.5-5 mass parts, the conventional matrix of cosmetics exterior-applied formulation and/ Or deionized water 92-99.3 mass parts.
6. cosmetics according to claim 5, it is characterised in that:The toiletry bag contains following groups of following mass parts Point:Tomato antioxygen element 1-2 mass parts, Flos micheliae Albae extract 2-5 mass parts and/or are gone at the conventional matrix of cosmetics exterior-applied formulation Ionized water is 93-97 mass parts.
7. cosmetics according to claim 6, it is characterised in that:The toiletry bag contains following groups of following mass parts Point:Tomato antioxygen element 1.5 mass parts, the mass parts of Flos micheliae Albae extract 5, the conventional matrix of cosmetics exterior-applied formulation and/or go from Sub- water is 93.5 mass parts.
8. cosmetics according to claim 4, it is characterised in that:State of cosmetics includes cream shape, emulsion form or elite Honey.
9. cosmetics according to claim 4, it is characterised in that:The conventional matrix of the cosmetics exterior-applied formulation includes breast One or more in agent, grease, emollient, NMF, thickener, polyalcohol, preservative and essence.
10. application of the antioxidant composition described in claim 1 in cosmetics are prepared.
CN201710318601.0A 2017-05-08 2017-05-08 A kind of antioxidant composition and cosmetics and application Pending CN107157824A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111803415A (en) * 2020-07-16 2020-10-23 广州市澳键丰泽生物科技股份有限公司 Plant essential oil nano emulsion, preparation method thereof and application thereof in lip products

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101897441A (en) * 2010-07-09 2010-12-01 晨光生物科技集团天津有限公司 Soft capsule of lycopene
CN103948529A (en) * 2014-01-26 2014-07-30 广州丹奇日用化工厂有限公司 Cosmetic combination containing tomato pulp extract
CN105310932A (en) * 2015-10-26 2016-02-10 深圳市仙迪化妆品有限公司 Cosmetic composition containing tomato fruit extract and preparation method thereof
CN106166130A (en) * 2016-08-25 2016-11-30 广州合诚三先生物科技有限公司 The Fructus Hippophae with self-corrosion protection function repairs lip gloss and preparation method thereof
CN106214529A (en) * 2016-09-09 2016-12-14 江南大学 A kind of food stage hand cream

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101897441A (en) * 2010-07-09 2010-12-01 晨光生物科技集团天津有限公司 Soft capsule of lycopene
CN103948529A (en) * 2014-01-26 2014-07-30 广州丹奇日用化工厂有限公司 Cosmetic combination containing tomato pulp extract
CN105310932A (en) * 2015-10-26 2016-02-10 深圳市仙迪化妆品有限公司 Cosmetic composition containing tomato fruit extract and preparation method thereof
CN106166130A (en) * 2016-08-25 2016-11-30 广州合诚三先生物科技有限公司 The Fructus Hippophae with self-corrosion protection function repairs lip gloss and preparation method thereof
CN106214529A (en) * 2016-09-09 2016-12-14 江南大学 A kind of food stage hand cream

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111803415A (en) * 2020-07-16 2020-10-23 广州市澳键丰泽生物科技股份有限公司 Plant essential oil nano emulsion, preparation method thereof and application thereof in lip products

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