CN107050405A - One kind treats dermopathic capsule medicine and preparation method thereof - Google Patents

One kind treats dermopathic capsule medicine and preparation method thereof Download PDF

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Publication number
CN107050405A
CN107050405A CN201710076800.5A CN201710076800A CN107050405A CN 107050405 A CN107050405 A CN 107050405A CN 201710076800 A CN201710076800 A CN 201710076800A CN 107050405 A CN107050405 A CN 107050405A
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CN
China
Prior art keywords
medicine
dermopathic
radix scrophulariae
disease
capsule
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CN201710076800.5A
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Chinese (zh)
Inventor
罗兴兰
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Sichuan Shuangxin Biological Technology Co Ltd
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Sichuan Shuangxin Biological Technology Co Ltd
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Priority to CN201710076800.5A priority Critical patent/CN107050405A/en
Publication of CN107050405A publication Critical patent/CN107050405A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to treat dermopathic capsule medicine according to one kind that the traditional Chinese medical science is provided dermopathic understanding mechanism, each component and its mass parts ratio of the medicine are as follows:30~120g of ginseng, 150~260g of radix scrophulariae, 30~80g of rhizoma zingiberis, 60~150g of the radix paeoniae rubrathe, 30~120g of hawthorn, 90~160g of radix scrophulariae, 25~160g of rattletop, 80~160g of schizonepeta, 2.5~5g of crotons, 150~480g of gypsum, 30~120g of Ligusticum wallichii;The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

One kind treats dermopathic capsule medicine and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to one kind treats dermopathic capsule medicine, particularly for skin The field of the capsule medicine that skin patient uses and preparation method thereof.
Background technology
Skin disease(dermatosis)It is to occur in skin and the general name of skin accessory organ's disease.Skin is that human body is maximum Organ, dermopathic species is not only various, and the disease that a variety of internal organ occur can also have performance on skin.Cause skin disease The reason for it is a lot, such as skin disease caused by infective agent, such as leprosy, scabies, nosomycosis, bacterial skin infections usually have one Fixed infectiousness, not only influences healthy, and raises fear and social discrimination, but with the improvement of people ' s living standards And scientific and technological progress, the infectious disease such as leprosy has been obviously controlled in the whole world.Other cause it is dermopathic it is inside and outside because Element, such as mechanicalness, it is physical, chemically, biological, incretion, immunity.
Skin disease is to perplex the class disease of human lives always.Although being not enough to fatal, skin disease would generally make one Produce that red, the symptom such as swell, itch, if epiderm skin is also easy to cause bacterium or fungal infection because of itching by destruction, more The state of an illness is aggravated, the live and work of the mankind is had a strong impact on.Therefore, increasingly it is valued by people.
So, dermopathic medicine can be effectively treated with regard to how to find one kind, be an urgent problem needed to be solved.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment skin disease, people gradually appreciate Chinese traditional treatment Dermopathic advantage, and the advantage such as good effect, instant effect, toxic side effect be small over the course for the treatment of, for existing western medical treatment skin The present situation of skin disease, the purpose of the present invention is to be that providing one kind treats dermopathic capsule medicine, to solve dermatosis patient The problem of getting well early.The medicine be using common Chinese medicine as raw material, can by selecting rational medicine and mass parts ratio Effectively treat above-mentioned skin disease.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:One kind is provided and treats dermopathic glue Wafer medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
30~120g of ginseng, 150~260g of radix scrophulariae, 30~80g of rhizoma zingiberis, 60~150g of the radix paeoniae rubrathe, 30~120g of hawthorn, radix scrophulariae 90~ 160g, 25~160g of rattletop, 80~160g of schizonepeta, 2.5~5g of crotons, 150~480g of gypsum, 30~120g of Ligusticum wallichii.
One kind treats dermopathic capsule medicine and preparation method thereof, it is characterised in that each component of the medicine And its mass parts are than as follows:
35~105g of ginseng, 170~230g of radix scrophulariae, 35~70g of rhizoma zingiberis, 70~130g of the radix paeoniae rubrathe, 35~105g of hawthorn, radix scrophulariae 100 ~140g, 30~140g of rattletop, 90~140g of schizonepeta, 3~4.5g of crotons, 130~480g of gypsum, 35~105g of Ligusticum wallichii.
One kind treats dermopathic capsule medicine and preparation method thereof, it is characterised in that the medicine of " preferred plan " Each component and its mass parts of thing are than as follows:
Ginseng 90g, radix scrophulariae 200g, rhizoma zingiberis 60g, radix paeoniae rubrathe 115g, hawthorn 95g, radix scrophulariae 120g, rattletop 120g, schizonepeta 120g, crotons 4g, gypsum 420g, Ligusticum wallichii 95g.
One kind treats dermopathic capsule medicine and preparation method thereof, it is characterised in that methods described includes following step Suddenly it is prepared from:
A, above-mentioned raw materials Chinese medicine is picked to impurity, dust and dried after, be ground into superfine end according to mass parts ratio standby;
B, the method for preparing Chinese medicine capsules according to tradition, after ground superfine myrrh thing sieving, are put into medicine device and mix Uniformly, then it is prepared into capsule(The sealed rear total length of its capsule is 23.3mm, medicinal powder capacity 0.4~0.5g/), Jin Erfen Dress sealing.
One kind treats dermopathic capsule medicine and preparation method thereof, it is characterised in that the instructions of taking is:Will system The capsule medicine got ready is twice a day to take, and once a dose sooner or later, dosage 2g(4)/ time, warm water is sent down, 30 days For a course for the treatment of, 1~3 course for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Ginseng, nature and flavor:Mild-natured, sweet, slight bitter, with reinforcing vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid to quench thirst, tranquilize the mind and promote the intelligence The effect of, for treat deficient internal lesion caused by overexertion, deficiency of food, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, be good for Forget, dizziness and headache, impotence, frequent micturition, quench one's thirst, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, the card of all qi-blood-body fluid deficiencies;
Radix scrophulariae, nature and flavor:It is bitter salty, cool, the effect of with enriching yin, fall fire, relieving restlessness, removing toxic substances, for treat consumption of YIN caused by febrile disease, tongue unravel silk it is tired Yearningly, hair spot, hectic fever due to yin labor heat, night sleep not peaceful, spontaneous sweating, Tianjin hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula, epidemic heat syndrome Send out spot, hot eyes, diphtheria, sore;
Rhizoma zingiberis, nature and flavor:Pungent, heat, the effect of with middle benefit gas by cold, Back to Yang Tongmai, for treating trusted subordinate's crymodynia, vomiting and diarrhoea, the cold arteries and veins of limb Breath with cough for micro-, cold time, wind-cold-dampness arthralgia, the deficiency of yang are told, is defeated in battle, lower blood;
The radix paeoniae rubrathe, nature and flavor:It is bitter, be slightly cold, the effect of with clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down;
Hawthorn, nature and flavor:Sour sweet, tepor, it is nontoxic, with digestion gathered food, change the stagnant stasis of blood the effect of, for Therapeutic diet to be stagnant, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia;
Radix scrophulariae, nature and flavor:Sweet, bitter, salty, cold nature, the effect of with clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass, for treating Warm heat disease heat and ying blood, body heat, polydipsia, tongue are deep red, send out spot, hectic fever due to yin labor is coughed, dysphoria not puckery dim-sighted, the throat larynx of awake, Tianjin hinder constipation, mesh Swell and ache, scrofula subcutaneous nodule, skin sore;
Rattletop, nature and flavor:It is sweet pungent slight bitter, cool, with rising Yang, deliver, promoting eruption, removing toxic substances the effect of, gas plague, headache during for treating Fever and chills, laryngalgia, aphtha, macula are impermeable, the sinking of qi of middle-jiao, protracted dysentery and diarrhea, prolapse of the anus, women are collapsed, band, uterus tenesmus, carbuncle sore tumefacting virus;
Schizonepeta, nature and flavor:Pungent, temperature, with delivering, wind-dispelling, regulating blood condition, fries charcoal hemostasis the effect of, for treat cold, fever, headache, Abscess of throat, apoplexy lockjaw, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, the disease such as scrofula;
Crotons, nature and flavor:Pungent, heat is very toxic, with rushing down cold product, orifice opening, by phlegm, water-filling, the effect of desinsection, cold for treating Product stagnates, fullness and oppression of chest and abdomen shoot, blood lump in the abdomen, phlegm addiction, rush down dysentery, oedema, and external application controls sore-throat, larynx numbness, malignant sore mange, control cold product stagnate, Fullness and oppression of chest and abdomen shoot, blood lump in the abdomen, phlegm addiction, rush down dysentery, oedema, sore-throat, larynx numbness, malignant sore mange;
Gypsum, nature and flavor:Xin Gan, cold, the effect of quenching the thirst with expelling pathogenic factors from muscles for clearing heat, relieving restlessness, do not moved back for treating pyreticosis high fever, vexed god Dusk, delirious speech is gone mad, thirsty and dry pharynx, lung heat breathe heavily urgency, heatstroke spontaneous perspiration, stomach headache due to fire-evil, toothache, heat toxin stop up Shengs, spot dermexanthesis, dispute give birth to Sore, forge deposited myogenic sore, control outside ulcer sores, burst do not close up, the burning hot wound of soup;
Ligusticum wallichii, nature and flavor:Pungent, temperature, the effect of with promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating irregular menstruation, warp Close the stagnant raw meat pain of dysmenorrhoea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sores.
Medicine of the present invention is to be based on the dermopathic principle of Chinese traditional treatment, is thought from pharmacological action and mechanism of action:With regard to skin Each raw material herbal medicine efficacy in disease, medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at above-mentioned treating for skin disease, the medicine prepared using the formula Thing good drug efficacy, instant effect is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail:
Embodiment 1:
One kind treats dermopathic capsule medicine, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Ginseng 90g, radix scrophulariae 200g, rhizoma zingiberis 60g, radix paeoniae rubrathe 115g, hawthorn 95g, radix scrophulariae 120g, rattletop 120g, schizonepeta 120g, crotons 4g, gypsum 420g, Ligusticum wallichii 95g.
Embodiment 2:
One kind treats dermopathic capsule medicine, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Ginseng 105g, radix scrophulariae 230g, rhizoma zingiberis 70g, radix paeoniae rubrathe 130g, hawthorn 105g, radix scrophulariae 140g, rattletop 140g, schizonepeta 140g, bar Beans 4.5g, gypsum 480g, Ligusticum wallichii 105g.
Embodiment 3:
One kind treats dermopathic capsule medicine, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown:
Ginseng 120g, radix scrophulariae 260g, rhizoma zingiberis 80g, radix paeoniae rubrathe 150g, hawthorn 120g, radix scrophulariae 160g, rattletop 160g, schizonepeta 160g, bar Beans 5g, gypsum 480g, Ligusticum wallichii 120g.
Model case
Through clinical conditions dermatosis patient totally 456, the age is 315 of more than 37 years old, only 141 for 37 years old with Under.350 fully recovered in 456 patients, effective 106, total effective rate is up to 100%.

Claims (3)

1. one kind treats dermopathic capsule medicine, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower:
30~120g of ginseng, 150~260g of radix scrophulariae, 30~80g of rhizoma zingiberis, 60~150g of the radix paeoniae rubrathe, 30~120g of hawthorn, radix scrophulariae 90~ 160g, 25~160g of rattletop, 80~160g of schizonepeta, 2.5~5g of crotons, 150~480g of gypsum, 30~120g of Ligusticum wallichii.
2. the dermopathic capsule medicine for the treatment of according to claim 1, it is characterised in that each component of the medicine And its mass parts are than as follows:
35~105g of ginseng, 170~230g of radix scrophulariae, 35~70g of rhizoma zingiberis, 70~130g of the radix paeoniae rubrathe, 35~105g of hawthorn, radix scrophulariae 100 ~140g, 30~140g of rattletop, 90~140g of schizonepeta, 3~4.5g of crotons, 130~480g of gypsum, 35~105g of Ligusticum wallichii.
3. the dermopathic capsule medicine for the treatment of according to claim 1 to 2, it is characterised in that the medicine each Component and its mass parts are than as follows:
Ginseng 90g, radix scrophulariae 200g, rhizoma zingiberis 60g, radix paeoniae rubrathe 115g, hawthorn 95g, radix scrophulariae 120g, rattletop 120g, schizonepeta 120g, crotons 4g, gypsum 420g, Ligusticum wallichii 95g.
CN201710076800.5A 2017-02-13 2017-02-13 One kind treats dermopathic capsule medicine and preparation method thereof Withdrawn CN107050405A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52130903A (en) * 1976-04-21 1977-11-02 Kunitarou Maruo Rubbing liquid of planttorigin
CN102772762A (en) * 2012-07-12 2012-11-14 张群 Traditional Chinese medicinal active ingredient composition for treating skin diseases and method for preparing traditional Chinese medicinal active ingredient composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52130903A (en) * 1976-04-21 1977-11-02 Kunitarou Maruo Rubbing liquid of planttorigin
CN102772762A (en) * 2012-07-12 2012-11-14 张群 Traditional Chinese medicinal active ingredient composition for treating skin diseases and method for preparing traditional Chinese medicinal active ingredient composition

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Application publication date: 20170818