CN107050227A - A kind of herbal essences combination eye sticker and preparation method for treating eye visual fatigue disease - Google Patents

A kind of herbal essences combination eye sticker and preparation method for treating eye visual fatigue disease Download PDF

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Publication number
CN107050227A
CN107050227A CN201710462558.5A CN201710462558A CN107050227A CN 107050227 A CN107050227 A CN 107050227A CN 201710462558 A CN201710462558 A CN 201710462558A CN 107050227 A CN107050227 A CN 107050227A
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parts
eye
woven fabrics
visual fatigue
decoction
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傅波
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Qingdao Eboman Biological Science And Technology Co Ltd
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Qingdao Eboman Biological Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

Eye sticker is combined the invention discloses a kind of herbal essences for treating eye visual fatigue disease, the hot castrate package absorbed including pharmaceutical film and for ancillary drug, the pharmaceutical film is by load stype and is impregnated in and carries the decoction on stype and constitute, and the decoction extracted is formed by the Chinese medicine material of following parts by weight:11~35 parts of safflower, yellow 52~95 parts of dog courage, 52~95 parts of mulberry leaf, 52~95 parts of cassia seed, 52~95 parts of chrysanthemum, 95~155 parts of matrimony vine, 52~95 parts of bat's faces, 52~95 parts of climbing groundsel, 5~9 parts of Moschus, 21~35 parts of borneol, 52~95 parts of the seed of cowherb, 52~95 parts of Ligusticum wallichii, 52~95 parts of pipewort, 63~95 parts of grass-leaved sweetflag, 85~155 parts of Semen Leonuri.Cure rate is high, and determined curative effect does not rebound;The crowd of being applicable is wide, is particularly suitable for teenager, early treatment, early rehabilitation to A nearsighted person, it is early be benefited it is significant;Using pure Chinese medicinal preparation, using safety, have no toxic side effect;Using simple, easily popularize.

Description

A kind of herbal essences combination eye sticker and preparation method for treating eye visual fatigue disease
Technical field
Myopia, astigmatism, strabismus, amblyopia, presbyopic are treated the present invention relates to Chinese herb medicine eye paste technical field, more particularly to one kind The herbal essences combination eye sticker and preparation method of the eye visual fatigue diseases such as eye, eyeground ischemic disease.
Background technology
Kopiopia is a kind of ophthalmology common disease, and the eye caused by it is dry, eye is puckery, eye is sour swollen, under blurred vision even eyesight Drop directly affects the work and life of people.When kopiopia usually concentrates to see computer screen mainly due to us, eyes Number of winks is reduced, and causes tears Secretion to reduce, while flashing caused by the intense stimulus eyes of fluorescent screen.It can cause people The corresponding site such as neck, shoulder there is pain, can also trigger and aggravate various illness in eye.It is various for the alleviation method of eye fatigue Various kinds, but popular receiving is also just so several:(1) rest more;(2) replenishing vitamins;(3) using eye drops and it is eye guarantor Strong behaviour.
Kopiopia reason has the following aspects:
Ophthalmic refractive is abnormal:When with long sight, myopia, astigmatism, presbyopia, see that eyes are required for employing very big tune when far seeing near Power is saved, eyes is overworked.Excessive eye set:When myopia does not obtain correction, caused because reading distance is too near Degree set, excessively set again can with excessively regulation, increase myopic degree, reading distance closer to.So occur vicious circle, So that producing kopiopia.
Continuous shift the focus:Under astigmatism symptom, imaging is accomplished by using intraocular ciliary muscle when can not be on a point Adjustment effect, carry out constantly shift the focus, exceedingly with regulation, ciliary muscle is also related to head nerves, in the course of time, eyelash The tired out of shape flesh can cause corresponding nerve pain.
Disease of eye:With blurring of vision caused by nebula, phacoscotasmus and other eye illnesses, also easily cause eye Fatigue.
Dysplasia of eye:Such as two eye pupils are also easy to produce kopiopia away from larger, two set difficulties.
Constitution and life factor:Do not get enough athletic exercise such as, it is malnutritive, often have a sleepless night, no rule of living, excessive drinking and smoking, Eye hygiene etc. is not noted, easily occurs kopiopia.
Age factor:The people of more than 40 years old, eyes start aging, but do not match somebody with somebody presbyopic glasses in time, easily occur kopiopia.
Environmental factor:Work or the illumination of study place are not enough;The writing or working substance of read-write are too small;Target and background difference It is not distinct;Read-write and longevity of service;Sighting distance does not fix (such as on car and boat read and write and work), eyes can be caused nervous with Excessive use adjusting force, works to eyes excess load, and not only easily occurs kopiopia, but also can cause myopia and other diseases Disease.
The content of the invention
In view of the deficienciess of the prior art, the technical problems to be solved by the invention, which are to provide a kind of scattered stasis of blood, dredges arteries and veins, it is living Blood relaxing muscles and tendons, moistening for dryness and clearing away heat, sensible improving eyesight can prevent Eye disease, effective relieving eye strain, confrontation visual impairment moisten Eye, the herbal essences combination eye sticker and preparation method for alleviating the treatment eye visual fatigue disease that eyes are dried.
In order to solve the above technical problems, the technical solution used in the present invention is:A kind of eye visual fatigue disease for the treatment of Herbal essences combine eye sticker, including pharmaceutical film and the hot castrate package that is absorbed for ancillary drug, the pharmaceutical film by load stype and The decoction composition carried on stype is impregnated in, the decoction extracted is formed by the Chinese medicine material of following parts by weight:Safflower 11~ 35 parts, yellow 52~95 parts of dog courage, 52~95 parts of mulberry leaf, 52~95 parts of cassia seed, 52~95 parts of chrysanthemum, 95~155 parts of matrimony vine, night Bright 52~95 parts of sand, 52~95 parts of climbing groundsel, 5~9 parts of Moschus, 21~35 parts of borneol, 52~95 parts of the seed of cowherb, Ligusticum wallichii 52~ 95 parts, 52~95 parts of pipewort, 63~95 parts of grass-leaved sweetflag, 85~155 parts of Semen Leonuri.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the decoction by following parts by weight Chinese medicine material It is extracted to form:11 parts of safflower, yellow 52 parts of dog courage, 52 parts of mulberry leaf, 52 parts of cassia seed, 52 parts of chrysanthemum, 95 parts of matrimony vine, bat's faces 52 parts, 52 parts of climbing groundsel, 5 parts of Moschus, 21 parts of borneol, 52 parts of the seed of cowherb, 52 parts of Ligusticum wallichii, 52 parts of pipewort, 63 parts of grass-leaved sweetflag, 85 parts of Semen Leonuri.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the decoction by following parts by weight Chinese medicine Raw material is extracted to be formed:20 parts of safflower, yellow 73 parts of dog courage, 73 parts of mulberry leaf, 73 parts of cassia seed, 73 parts of chrysanthemum, 125 parts of matrimony vine, 73 parts of bat's faces, 73 parts of climbing groundsel, 7 parts of Moschus, 28 parts of borneol, 73 parts of the seed of cowherb, 73 parts of Ligusticum wallichii, 73 parts of pipewort, stone Chang 78 parts of Pu, 120 parts of Semen Leonuri.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the decoction by following parts by weight Chinese medicine Raw material is extracted to be formed:35 parts of safflower, yellow 95 parts of dog courage, 95 parts of mulberry leaf, 95 parts of cassia seed, 95 parts of chrysanthemum, 155 parts of matrimony vine, 95 parts of bat's faces, 95 parts of climbing groundsel, 9 parts of Moschus, 35 parts of borneol, 95 parts of the seed of cowherb, 95 parts of Ligusticum wallichii, 95 parts of pipewort, stone Chang 95 parts of Pu, 155 parts of Semen Leonuri.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the hot castrate package is by heating eyeshade and difference The acupuncture point paster composition between two temple and two eyebrows is adhered to, the heating eyeshade includes two layers of applying film nonwoven being bonded to one another Cloth, is filled with heating bag between two layers of applying film non-woven fabrics, and heating temp scope is 40 DEG C~70 DEG C, two layers of applying film nonwoven The both ends that any one layer of cloth are sewed with the fixing band for wearing respectively.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the acupuncture point paster includes containing pressure sensitive adhesive Non-woven fabrics, medicine layer is applied on non-woven fabrics, on the non-woven fabrics containing pressure sensitive adhesive one side paste silicone oil protection sheet, it is described pressure-sensitive Peel strength >=1.0N/cm of glue, holds sticky > 2.5mm.
The herbal essences combination eye sticker of above-mentioned treatment eye visual fatigue disease, the load stype is non-woven fabrics, non-woven fabrics Shape be cut to and the circular of human body eye profiling, ellipse or rectangle.
A kind of method that herbal essences for preparing treatment eye visual fatigue disease as claimed in claim 1 combine eye sticker, Comprise the following steps:
(1), weigh, cleaning:Chinese medicine safflower, yellow dog courage, mulberry leaf, cassia seed, chrysanthemum, matrimony vine, bat's faces, thousand are weighed in proportion In light, Moschus, the seed of cowherb, Ligusticum wallichii, pipewort, grass-leaved sweetflag, Semen Leonuri, then with pure water clean;
(2), drying, crush:By step(1)In each taste Chinese medicine for cleaning be put into drying in dryer, then carried out with pulverizer Attrition grinding is to powdered, and attrition grinding granularity is the mesh of 150 mesh~300, is taken out standby;
(3), borneol crush:Borneol is weighed in proportion, and borneol is put into the independent attrition grinding of pulverizer to powdered, attrition grinding Granularity is the mesh of 150 mesh~300, is taken out standby;
(4), medicinal powder prepare:By step(2)、(3)Obtained two kinds of powder mixing, is put into batch mixer and is sufficiently stirred for 1 hour, make Into medicinal powder mixture;
(5), decoction prepare:Medicinal powder mixture is put into 110~150 DEG C, 0.25MPa extraction cylinder and carries out that to boil 1~3 small When, filtration, filtrate is condensed into thick liquid;Sterilizing in retort is then placed in, deionized water is then added and is diluted to dilution, then The pH value for adjusting dilution with the NaOH aqueous solution is well mixed to obtain decoction to 6.2~7.0;
(6), eye sticker prepare:Use non-woven fabrics impregnation steps(5)Obtained decoction simultaneously soaks non-woven fabrics to decoction completely;
(7), packaging complete:The wet non-woven fabrics pack of decoction will be impregnated, every bag a piece of, and sealing is got product.
The herbal essences of above-mentioned treatment eye visual fatigue disease combine the preparation method of eye sticker, the step(5)Middle system The relative density of the thick liquid obtained is 1.14~1.24g/ml, and the relative density of the dilution after being diluted through deionized water is 1.006~1.01g/ml, NaOH concentration of aqueous solution are 4.1~4.5mol/L.
The herbal essences of above-mentioned treatment eye visual fatigue disease combine the preparation method of eye sticker, the step(5)In it is dense The sterilising temp of magma is 83~87 DEG C, sterilization time 1~3 minute.
The herbal essences combination eye sticker of present invention treatment eye visual fatigue disease and the advantage of preparation method are:With conventional dry The medicine eye sticker of formula is compared, and the present invention acts directly on eye using decoction, is administered and works by circumference of eyes channels and collaterals.This Invention is refining to obtain use according to theory of traditional Chinese medical science and Drug Percutaneous Absorption technology, selected pharmaceutical formulation with reference to tradition and modern crafts In treatment myopia eye sticker, be directly applied to acupuncture point around eye, with promoting blood circulation latus rectum, clear liver and improve vision, inducing resuscitation it is sensible it Effect, by permanent balanced release medicine, stimulates circumference of eyes neural sensor and peripheral vessel, is effectively improved circumference of eyes blood Liquid is circulated and interior nerve modulation, improves the blood circulation and metabolism of part tissue of eye, recovers the Physiological effect of eye muscle, so that reaching has Effect improves the purpose of visual rehabilitation.Using heating eyeshade and acupuncture point paster collective effect, eye is served to pharmaceutical film Chinese medicine liquid Assist absorption effect.The mode that pharmaceutical film is separated with hot castrate package, is applied in combination when using, and more facilitates.Demonstrate,proved through clinical test Bright, product of the present invention is used to treat myopia, and recovery period is short, and cure rate is high, and determined curative effect does not rebound;Product of the present invention is applicable Crowd is wide, is particularly suitable for teenager, and early treatment, early rehabilitation to A nearsighted person, morning are benefited significant;Product of the present invention Using pure Chinese medicinal preparation, using safety, have no toxic side effect, devoid of risk and sequelae;Product of the present invention is easily promoted general using simple And, more A nearsighted persons can be made to be benefited.
Brief description of the drawings
Fig. 1 is the structural representation of pharmaceutical film of the present invention;
The overall structure diagram of Fig. 2 hot castrate packages of the present invention;
Fig. 3 is the cross section structure diagram of hot castrate package;
Fig. 4 is the structural representation of acupuncture point paster.
Embodiment
Below in conjunction with the accompanying drawings and specific embodiment is described in further details to the present invention;
Embodiment 1:
As shown in Figure 1,2,3, 4, a kind of herbal essences combination eye sticker for treating eye visual fatigue disease, including pharmaceutical film 1 and use The hot castrate package absorbed in ancillary drug, the pharmaceutical film 1 is made up of load stype 2 and the decoction 3 being impregnated on load stype 2.Institute It is non-woven fabrics to state load stype 2, and the shape of non-woven fabrics is cut to and the circular of human body eye profiling, ellipse or rectangle.
Hot castrate package is by heating eyeshade 4 and adheres to the acupuncture point paster 5 between two temple and two eyebrows respectively and constitutes, the hair Hot eyeshade 4 includes two layers of applying film non-woven fabrics 5 being bonded to one another, and heating bag 6, heating are filled between two layers of applying film non-woven fabrics 5 Temperature range is 40 DEG C~70 DEG C, and the both ends of 5 any one layers of two layers of applying film non-woven fabrics are sewed with for wearing respectively Fixing band 7.Acupuncture point paster 5 includes the non-woven fabrics 9 containing pressure sensitive adhesive 8, and medicine layer 10 is applied on non-woven fabrics 9, contains pressure sensitive adhesive 8 Silicone oil protection sheet 11, peel strength >=1.0N/cm of the pressure sensitive adhesive 8 are pasted on non-woven fabrics 5 simultaneously, sticky > 2.5mm are held.
The decoction extracted is formed by the Chinese medicine material of following parts by weight:11 parts of safflower, yellow 52 parts of dog courage, mulberry leaf 52 Part, 52 parts of cassia seed, 52 parts of chrysanthemum, 95 parts of matrimony vine, 52 parts of bat's faces, 52 parts of climbing groundsel, 5 parts of Moschus, 21 parts of borneol, Wang Buliu 52 parts of row, 52 parts of Ligusticum wallichii, 52 parts of pipewort, 63 parts of grass-leaved sweetflag, 85 parts of Semen Leonuri.
A kind of method that herbal essences for preparing treatment eye visual fatigue disease combine eye sticker, comprises the following steps:
(1), weigh, cleaning:Chinese medicine safflower, yellow dog courage, mulberry leaf, cassia seed, chrysanthemum, matrimony vine, bat's faces, thousand are weighed in proportion In light, Moschus, the seed of cowherb, Ligusticum wallichii, pipewort, grass-leaved sweetflag, Semen Leonuri, then with pure water clean;
(2), drying, crush:By step(1)In each taste Chinese medicine for cleaning be put into drying in dryer, then carried out with pulverizer Attrition grinding is to powdered, and attrition grinding granularity is the mesh of 150 mesh~300, is taken out standby;
(3), borneol crush:Borneol is weighed in proportion, and borneol is put into the independent attrition grinding of pulverizer to powdered, attrition grinding Granularity is the mesh of 150 mesh~300, is taken out standby;
(4), medicinal powder prepare:By step(2)、(3)Obtained two kinds of powder mixing, is put into batch mixer and is sufficiently stirred for 1 hour, make Into medicinal powder mixture;
(5), decoction prepare:Medicinal powder mixture is put into 110 DEG C, 0.25MPa extraction cylinder and boil 1 hour, is filtered, filter Liquid is condensed into the thick liquid that relative density is 1.14g/ml;Sterilizing in retort is then placed in, the sterilising temp of thick liquid is 83 DEG C, then sterilization time 3 minutes adds deionized water and is diluted to dilution of the relative density for 1.006g/ml, then be with concentration The pH value of 4.1mol/L NaOH aqueous solution regulation dilution is well mixed to obtain decoction to 6.2;
(6), eye sticker prepare:Use non-woven fabrics impregnation steps(5)Obtained decoction simultaneously soaks non-woven fabrics to decoction completely;
(7), packaging complete:The wet non-woven fabrics pack of decoction will be impregnated, every bag a piece of, and sealing is got product.
Embodiment 2:
The present embodiment part same as Example 1 is repeated no more, and its difference is:The decoction is in following parts by weight Medicine raw material is extracted to be formed:20 parts of safflower, yellow 73 parts of dog courage, 73 parts of mulberry leaf, 73 parts of cassia seed, 73 parts of chrysanthemum, matrimony vine 125 Part, 73 parts of bat's faces, 73 parts of climbing groundsel, 7 parts of Moschus, 28 parts of borneol, 73 parts of the seed of cowherb, 73 parts of Ligusticum wallichii, 73 parts of pipewort, stone 78 parts of calamus, 120 parts of Semen Leonuri.
A kind of method that herbal essences for preparing treatment eye visual fatigue disease combine eye sticker, comprises the following steps:
(1), weigh, cleaning:Chinese medicine safflower, yellow dog courage, mulberry leaf, cassia seed, chrysanthemum, matrimony vine, bat's faces, thousand are weighed in proportion In light, Moschus, the seed of cowherb, Ligusticum wallichii, pipewort, grass-leaved sweetflag, Semen Leonuri, then with pure water clean;
(2), drying, crush:By step(1)In each taste Chinese medicine for cleaning be put into drying in dryer, then carried out with pulverizer Attrition grinding is to powdered, and attrition grinding granularity is the mesh of 150 mesh~300, is taken out standby;
(3), borneol crush:Borneol is weighed in proportion, and borneol is put into the independent attrition grinding of pulverizer to powdered, attrition grinding Granularity is the mesh of 150 mesh~300, is taken out standby;
(4), medicinal powder prepare:By step(2)、(3)Obtained two kinds of powder mixing, is put into batch mixer and is sufficiently stirred for 1 hour, make Into medicinal powder mixture;
(5), decoction prepare:Medicinal powder mixture is put into 130 DEG C, 0.25MPa extraction cylinder and boil 2 hours, is filtered, filter Liquid is condensed into the thick liquid that relative density is 1.19g/ml;Sterilizing in retort is then placed in, the sterilising temp of thick liquid is 85 DEG C, then sterilization time 2 minutes adds deionized water and is diluted to dilution of the relative density for 1.008g/ml, then be with concentration The pH value of 4.3mol/L NaOH aqueous solution regulation dilution is well mixed to obtain decoction to 6.6;
(6), eye sticker prepare:Use non-woven fabrics impregnation steps(5)Obtained decoction simultaneously soaks non-woven fabrics to decoction completely;
(7), packaging complete:The wet non-woven fabrics pack of decoction will be impregnated, every bag a piece of, and sealing is got product.
Embodiment 3:
The present embodiment part same as Example 1 is repeated no more, and its difference is:The decoction is in following parts by weight Medicine raw material is extracted to be formed:35 parts of safflower, yellow 95 parts of dog courage, 95 parts of mulberry leaf, 95 parts of cassia seed, 95 parts of chrysanthemum, matrimony vine 155 Part, 95 parts of bat's faces, 95 parts of climbing groundsel, 9 parts of Moschus, 35 parts of borneol, 95 parts of the seed of cowherb, 95 parts of Ligusticum wallichii, 95 parts of pipewort, stone 95 parts of calamus, 155 parts of Semen Leonuri.
A kind of method that herbal essences for preparing treatment eye visual fatigue disease combine eye sticker, comprises the following steps:
(1), weigh, cleaning:Chinese medicine safflower, yellow dog courage, mulberry leaf, cassia seed, chrysanthemum, matrimony vine, bat's faces, thousand are weighed in proportion In light, Moschus, the seed of cowherb, Ligusticum wallichii, pipewort, grass-leaved sweetflag, Semen Leonuri, then with pure water clean;
(2), drying, crush:By step(1)In each taste Chinese medicine for cleaning be put into drying in dryer, then carried out with pulverizer Attrition grinding is to powdered, and attrition grinding granularity is the mesh of 150 mesh~300, is taken out standby;
(3), borneol crush:Borneol is weighed in proportion, and borneol is put into the independent attrition grinding of pulverizer to powdered, attrition grinding Granularity is the mesh of 150 mesh~300, is taken out standby;
(4), medicinal powder prepare:By step(2)、(3)Obtained two kinds of powder mixing, is put into batch mixer and is sufficiently stirred for 1 hour, make Into medicinal powder mixture;
(5), decoction prepare:Medicinal powder mixture is put into 150 DEG C, 0.25MPa extraction cylinder and boil 3 hours, is filtered, filter Liquid is condensed into the thick liquid that relative density is 1.24g/ml;Sterilizing in retort is then placed in, the sterilising temp of thick liquid is 87 DEG C, then sterilization time 1 minute adds deionized water and is diluted to dilution of the relative density for 1.01g/ml, then be with concentration The pH value of 4.5mol/L NaOH aqueous solution regulation dilution is well mixed to obtain decoction to 7.0;
(6), eye sticker prepare:Use non-woven fabrics impregnation steps(5)Obtained decoction simultaneously soaks non-woven fabrics to decoction completely;
(7), packaging complete:The wet non-woven fabrics pack of decoction will be impregnated, every bag a piece of, and sealing is got product.
(One), application method:
1st, before using pharmaceutical film, first eye part skin is cleaned with hot water;
2 and then a pair of pharmaceutical films are attached on eye part skin, and appropriate gently massage;
3rd, hot castrate package is opened, heating eyeshade is covered in into pharmaceutical film, while acupuncture point paster is removed into silicone oil protection sheet, pasted respectively At place between the eyebrows at the temple of both sides and between two eyebrows;
4th, after 20~30 minutes, heating eyeshade and pharmaceutical film are thrown off, crosses and cleans out eye part skin again in 15~20 seconds;
5th, a pair of pharmaceutical films are applied daily, adhere to the treatment of 1 month course for the treatment of, be effectively improved the inconvenience that eye illness is brought, Sight is apparent;
6th, eye part skin damages the wounded, allergic person and pregnant woman disabling.
(Two), selection case standard:
1st, slight ametropia, the puckery kopiopia of eye dry eyes, ocular movemeut is unfavorable.
2nd, suitable for myopia, amblyopia, strabismus, astigmatism, presbyopia, eyeground ischemic disease crowd.
3rd, there is eye foreign body sense, eyelid sense of heaviness, blurred vision, photophobia to shed tears, the symptom such as absent minded.
4th, eyeball lesion, the feature such as eyeground pathological changes, cranium brain visual centre lesion are excluded.
Made by the decoction of the present invention using pure Chinese medicine, fully gather herbal nature, without any toxicity and side effects, by being attached to eye Portion's skin quickly absorbs, dissipate the stasis of blood dredge arteries and veins, activate blood and relax tendons, moistening for dryness and clearing away heat, sensible improving eyesight, to treatment myopia, astigmatism, strabismus, amblyopia, Presbyopia, eyeground ischemic have higher effect, are become apparent from especially for teen-age myopia therapeutic effect, and after healing It is uneasy to recur, commonly using the present invention, also there is certain effect to pre- myopia prevention.
Certainly, described above is not limitation of the present invention, and the present invention is also not limited to the example above, the art Those of ordinary skill, the present invention essential scope in, the variations, modifications, additions or substitutions made, should all belong to the present invention Protection domain.

Claims (10)

1. it is a kind of treat eye visual fatigue disease herbal essences combination eye sticker, including pharmaceutical film and for ancillary drug absorb Hot castrate package, the pharmaceutical film is made up of load stype and the decoction being impregnated on load stype, it is characterised in that the decoction is by such as The Chinese medicine material of lower parts by weight is extracted to be formed:11~35 parts of safflower, yellow 52~95 parts of dog courage, 52~95 parts of mulberry leaf, Cassia 52~95 parts of son, 52~95 parts of chrysanthemum, 95~155 parts of matrimony vine, 52~95 parts of bat's faces, 52~95 parts of climbing groundsel, Moschus 5~9 Part, 21~35 parts of borneol, 52~95 parts of the seed of cowherb, 52~95 parts of Ligusticum wallichii, 52~95 parts of pipewort, 63~95 parts of grass-leaved sweetflag, 85~155 parts of Semen Leonuri.
2. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 1, it is characterized in that, the medicine Liquid extracted is formed by the Chinese medicine material of following parts by weight:11 parts of safflower, yellow 52 parts of dog courage, 52 parts of mulberry leaf, 52 parts of cassia seed, 52 parts of chrysanthemum, 95 parts of matrimony vine, 52 parts of bat's faces, 52 parts of climbing groundsel, 5 parts of Moschus, 21 parts of borneol, 52 parts of the seed of cowherb, Ligusticum wallichii 52 Part, 52 parts of pipewort, 63 parts of grass-leaved sweetflag, 85 parts of Semen Leonuri.
3. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 1, it is characterized in that, the medicine Liquid extracted is formed by the Chinese medicine material of following parts by weight:20 parts of safflower, yellow 73 parts of dog courage, 73 parts of mulberry leaf, 73 parts of cassia seed, 73 parts of chrysanthemum, 125 parts of matrimony vine, 73 parts of bat's faces, 73 parts of climbing groundsel, 7 parts of Moschus, 28 parts of borneol, 73 parts of the seed of cowherb, Ligusticum wallichii 73 Part, 73 parts of pipewort, 78 parts of grass-leaved sweetflag, 120 parts of Semen Leonuri.
4. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 3, it is characterized in that, the medicine Liquid extracted is formed by the Chinese medicine material of following parts by weight:35 parts of safflower, yellow 95 parts of dog courage, 95 parts of mulberry leaf, 95 parts of cassia seed, 95 parts of chrysanthemum, 155 parts of matrimony vine, 95 parts of bat's faces, 95 parts of climbing groundsel, 9 parts of Moschus, 35 parts of borneol, 95 parts of the seed of cowherb, Ligusticum wallichii 95 Part, 95 parts of pipewort, 95 parts of grass-leaved sweetflag, 155 parts of Semen Leonuri.
5. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 1, it is characterized in that:The heat All of a sudden wrap by heating eyeshade and adhere to the acupuncture point paster between two temple and two eyebrows respectively and constitute, the heating eyeshade includes two The applying film non-woven fabrics that is bonded to one another of layer, is filled with heating bag between two layers of applying film non-woven fabrics, and heating temp scope is 40 DEG C~ 70 DEG C, the both ends of any one layer of two layers of applying film non-woven fabrics are sewed with the fixing band for wearing respectively.
6. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 5, it is characterized in that:The cave Position paster includes the non-woven fabrics containing pressure sensitive adhesive, and medicine layer is applied on non-woven fabrics, is glued on the non-woven fabrics containing pressure sensitive adhesive one side Silicone oil protection sheet is pasted, peel strength >=1.0N/cm of the pressure sensitive adhesive holds sticky > 2.5mm.
7. the herbal essences combination eye sticker for the treatment of eye visual fatigue disease according to claim 1, it is characterized in that:It is described to carry Stype is non-woven fabrics, and the shape of non-woven fabrics is cut to and the circular of human body eye profiling, ellipse or rectangle.
8. a kind of method that herbal essences for preparing treatment eye visual fatigue disease as claimed in claim 1 combine eye sticker, its It is characterised by, comprises the following steps:
(1), weigh, cleaning:Chinese medicine safflower, yellow dog courage, mulberry leaf, cassia seed, chrysanthemum, matrimony vine, bat's faces, thousand are weighed in proportion In light, Moschus, the seed of cowherb, Ligusticum wallichii, pipewort, grass-leaved sweetflag, Semen Leonuri, then with pure water clean;
(2), drying, crush:By step(1)In each taste Chinese medicine for cleaning be put into drying in dryer, then carried out with pulverizer Attrition grinding is to powdered, and attrition grinding granularity is the mesh of 150 mesh~300, is taken out standby;
(3), borneol crush:Borneol is weighed in proportion, and borneol is put into the independent attrition grinding of pulverizer to powdered, attrition grinding Granularity is the mesh of 150 mesh~300, is taken out standby;
(4), medicinal powder prepare:By step(2)、(3)Obtained two kinds of powder mixing, is put into batch mixer and is sufficiently stirred for 1 hour, make Into medicinal powder mixture;
(5), decoction prepare:Medicinal powder mixture is put into 110~150 DEG C, 0.25MPa extraction cylinder and carries out that to boil 1~3 small When, filtration, filtrate is condensed into thick liquid;Sterilizing in retort is then placed in, deionized water is then added and is diluted to dilution, then The pH value for adjusting dilution with the NaOH aqueous solution is well mixed to obtain decoction to 6.2~7.0;
(6), eye sticker prepare:Use non-woven fabrics impregnation steps(5)Obtained decoction simultaneously soaks non-woven fabrics to decoction completely;
(7), packaging complete:The wet non-woven fabrics pack of decoction will be impregnated, every bag a piece of, and sealing is got product.
9. the herbal essences for the treatment of eye visual fatigue disease according to claim 8 combine the preparation method of eye sticker, it is special Levying is:The step(5)In the relative density of obtained thick liquid be 1.14~1.24g/ml, it is dilute after being diluted through deionized water The relative density for releasing liquid is 1.006~1.01g/ml, and NaOH concentration of aqueous solution is 4.1~4.5mol/L.
10. the herbal essences for the treatment of eye visual fatigue disease according to claim 8 combine the preparation method of eye sticker, it is special Levying is:The step(5)In thick liquid sterilising temp be 83~87 DEG C, sterilization time 1~3 minute.
CN201710462558.5A 2017-06-19 2017-06-19 A kind of herbal essences combination eye sticker and preparation method for treating eye visual fatigue disease Pending CN107050227A (en)

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Application publication date: 20170818