CN107048386A - A kind of sexual function adjusts health food - Google Patents

A kind of sexual function adjusts health food Download PDF

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Publication number
CN107048386A
CN107048386A CN201710253064.6A CN201710253064A CN107048386A CN 107048386 A CN107048386 A CN 107048386A CN 201710253064 A CN201710253064 A CN 201710253064A CN 107048386 A CN107048386 A CN 107048386A
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health food
health products
sexual function
sexual
extract
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范盘生
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One Hundred Reed (nanjing) Biological Technology Co Ltd
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One Hundred Reed (nanjing) Biological Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses a kind of sexual function regulation health food and preparation method thereof, maca, ginseng, nutmeg, coix seed, gumbo extract, sealwort, ginkgo biloba extract, tribulus terrestris extraction, cinnamomum cassia extract, the fruit of Chinese wolfberry, barrenwort, L arginine, citrulling, zinc citrate.It is made by pulverizing and sieving → premixing → pelletizing drying → whole grain → total mixed → tabletting → coating → inner packing → outsourcing → storage.Present invention discover that the health food can obvious adjusting sexual function, with nontoxicity, safety, the advantages of orally available.

Description

A kind of sexual function adjusts health food
Technical field
The invention belongs to field of health care products, specifically, it is related to a kind of adjusting sexual function regulation health food.
Background technology
Sexual function is a complicated physiology course.The maintenance of normal sexual function relies on the cooperation of human body multisystem, is related to To the harmonious of nervous system, cardiovascular system, internal system and reproductive system, in addition, must also have well The psychology of the state of mind and health.When anomalous variation occurs in terms of said system or psychiatric, it will influence normality life Carry out livingly, influence the quality of sexual life, show sex dysfunction.Sex dysfunction is the obstacle of sexual behaviour and sexy feel, The exception or missing of sexual psychology and physiological reaction are often shown as, is the general name of a variety of different symptoms.Male sexual disfunction master To include dysaphrodisia, penile erectile dysfunction and defective ejaculation etc., there is within 40~70 years old 52% to suffer from different journeys in man according to statistics The sex dysfunction of degree.The incidence of disease of Female sexual dysfunction is also very high, it is believed that the 30%~60% of adult women can be accounted for, Wherein sexual desire and orgasm disorder is the most universal, and some women may never enjoy orgasm in life.
Sex dysfunction can generally be divided into feature sex dysfunction and the major class of organic sex dysfunction two.Male's property Dysfunction includes dysaphrodisia, penile erectile dysfunction, sexual dysfunction and defective ejaculation.Female sexual dysfunction hinders including sexual desire Hinder, sexual arousal dysfunction, orgasm disorder, dyspareunia etc..
The reason for causing sex dysfunction may be roughly divided into three classes：Biological factor, psychologic factors and cultural factor.
Sex dysfunction may be by heredity, health status, hormonal readiness, age, disease (including chronic disease, psychoneural System illness, endocrine system disease, reproductive organs lesion) etc. caused by many reasons.Medicine, long-term a large amount of excessive drinkings or drug addict, Also sex dysfunction occurs.
Influence of the psychologic factors to sexual function than more prominent, including mistake attitude towards sex, past property undergo influence, Negative Emotional caused by environmental factor, interpersonal difficulty and various extraneous factors etc..
Due to the influence of religion and culture background, there is prejudice to sexual life and (such as think that " a drop essence ten is dripped in some people Blood "), it is believed that vigour can be lost in sexual intercourse, subjective to abandon or reduce sexuality, and easily causing property is constrained.
Based on this, it is necessary to find sexual function Auto-regulator to ensure the normal of sexual function, prevent or correct the low of sexual function Descend or obstacle, or the generation of sexual dysfunction disease, the rehabilitation of acceleration etc. are prevented by the regulation of sexual function, it is existing Sexual function regulation health food is main based on Chinese medicine, and feature is to focus on health, and consumer needs long-term taking, is worked slow.
Therefore it provides a kind of new sexual function regulation product has realistic meaning.
The content of the invention
To solve above technical problem, an object of the present invention is to provide a kind of health food of adjusting sexual function.
The second object of the present invention is the health food preparation method for providing a kind of adjusting sexual function.
What one of the object of the invention was realized in：
A kind of sexual function adjusts health food, by weight comprising following components：
Above-mentioned health food is also added with pharmaceutic adjuvant.
Above-mentioned health food is oral liquid, beverage, tablet, capsule, spray or cutaneous permeable agent.
What the second object of the present invention was realized in：
A kind of sexual function adjusts health food preparation method, is made as follows：Supplementary material pulverizes and sieves → premixes → Granulation drying → whole grain → total mixed → tabletting → coating → inner packing → outsourcing → storage.
The mode of taking of described health food is daily 1~2 time, each 100-2000mg/kg body weight.
This health food is applied to adjusting sexual function, including increases sexual desire, improve voluptus, extend sex time and secondary Number.
This health food is applied to correct sex dysfunction；The correction sex dysfunction is fast for increase sexual desire, raising property Sense, extension sex time and number of times.
It is the main component of this health products below.
Maca (Maca)
Maca (Lepidium meyemii Walp), is that Cruciferae separate row Vegetable spp is annual or biennial herbaceous plant, Originate in the andes region of more than height above sea level 4000m in the middle part of Peru., can be in severe ecological condition because Maca is low temperature resistant, strong wind Lower growth, as one of local chief crop.Main Leaf-feeding insects are root, storage root 2~5cm of diameter that underground is expanded, surface Color is mostly yellow or purple, and meat is white or faint yellow, with penetrating odor and special butterscotch smell. At present, the high place of production (based on cultivation product) of maca is still in Andes Ka Huama fertile lands area (Carhuamayo) and Hu Ningqu (Junin).The out of condition of the ground such as other regional or external Germany, Czech is introduced a fine variety to Peru, and depauperation does not obtain satisfied As a result.It is the high and cold of 4000~4500m of height above sea level, high wind and high Rizhao Area maca suitable growth.
Maca (Maca) is the plant of dietotherapeutic, and special product is used as in South America Peru, local Inca, tonic, It is called Peru's ginseng.The ground such as Peru in South America, can be fried during maca root using fresh herb together with meat or other vegetables it is edible, after drying I.e. edible then is cooked with water or milk, for thousands of years, maca root is used to strengthen energy as food and herbal medicine, and sexual function is adjusted Section, improves sexual function, improves fertility, treatment female climacteric syndrome etc..
Ginseng (Panax ginseng)
Ginseng, also known as Asia are joined, and are the roots with meat at Northeast China popular name " wooden club ", pharmaceutically acceptable.Ginseng belongs to Araliaceae, is mainly grown in East Asia, particularly cold district.Ginseng is the common medicinal material in Asia, and northern Central America is also generally using flower Flag is joined.
Why very rare ginseng is, very rare, mainly relevant with its medical value.In medical book very early《Legendary god of farming's book on Chinese herbal medicine Through》In be considered as, ginseng has functions that " tonifying five zang organs, soothe the nerves, determine soul, stop palpitate with fear, remove pathogenic factor, happy intelligence development tomorrow ", " long Take macrobiosis of making light of one's life by commiting suicide ".Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》In also ginseng is extremely praised highly, it is believed that it can " control male woman all chronic diseases marked by deficiency of vital energy ".
Ginseng can isolate more than 30 and plant panaxoside, in addition, ginseng is also containing a variety of organic acids and esters, the life of various dimensions Element, sterol, enzyme and 20 various trace elements.
In daily life, ginseng and its preparation are frequently utilized for more afterwards recovering, strengthen muscle power, regulation hormone, reduction blood glucose With control blood pressure, control liver index and liver function health care etc..
Gumbo (Hibiscus esculentus L.)
The alias of gumbo has Abelmoschus esculentus, okra, Radix Solani ferocis etc..Africa is originated in, early 20th century China is introduced by India. Its edible portion is Fruit pod, tender and crisp succulence, lubricious oiliness, and fragrance is unique, deep to be favored by people.
Containing a kind of stickiness liquid matter and araban, galactan, rhamnosan, protein etc. in gumbo okra fruit, warp Often to eat with helping digest, strengthen muscle power, protection liver, the whole intestines of stomach invigorating.Gumbo contains the multiple nutritional components such as iron, calcium and carbohydrate, There is the effect of prevention anaemia.Gumbo contains vitamin A and β-carrotene etc., is beneficial to retinal health, safeguards eyesight；Wherein Rich in having zinc and selenium and other trace elements, human body anti-cancer, anticancer can be strengthened.Mucin in gumbo plays the role of to suppress sugar absorption, So in recent years again as the folk prescription for the treatment of diabetes.Gumbo also contains the special medicative composition of tool, and the strong kidney qi-restoratives of energy is right Male's organic disease has auxiliary therapeutic action, enjoys the good reputation of " plant vigour ".
L-arginine (Arginine)
Arginine be a kind of amino acid containing two basic groups and amino and guanidine radicals under physiological ph conditions, belong to alkali Acidic amino acid (PH 10.5~12.0), molecular formula is C6H14N4O2, molecular weight 174.20, fusing point:223~224 DEG C, white water chestnut Shape crystallization (being separated out from water, containing 2 molecular crystalline water) or monocline flaky crystal (nodeless mesh water), odorless, bitter；Soluble in water (0 Solubility is that solubility is 400g/L in 83g/L, 50 DEG C of water in DEG C water), it is atomic to be dissolved in ethanol, insoluble in ether in nature In with the presence of two kinds of isomers:Have important nutrition physiology effect in D-Arg and L-arginine, animal body is L- essences Propylhomoserin
L-arginine is the important source material of synthetic protein and creatine, is the smart ammonia of semi-dispensable amino acid in humans and animals body Acid has important physiology, metabolism and trophism, and almost institute utilizes Arg synthetic cells slurry albumen and core in a organized way in body Albumen arginine is promoting the synthesis of muscle internal protein, strengthens the immunity of body, cell division, wound restores and secretion swashs In the various physiology courses such as element, the premise material that important role's arginine is also internal synthesis NO is also all served as, and it is internal The increase of NO synthesis, for balance blood, strengthens blood flow, improves cardiac and cerebral blood-supply, strengthen blood vessel elasticity, recover vascular function effect Substantially.It is most strong vascular relaxing factor, with the function of resisting athero- artery sclerosis, adjust blood pressure, arginic a variety of biologies The extensive concern that function causes nutrition and Medical Research Work person is learned, so that one of focus studied as current amino acid.
Citrulling
Contain an important beneficiating ingredient in latest find watermelon ----citrulling.Amino acid is the base for constituting protein Our unit, citrulling is one kind of amino acid.The content of citrulling is all higher than any food in watermelon, and people are from watermelon earliest Thus middle extraction citrulling, citrulling gains the name.
Citrulling is to be generated from ornithine and carbamyl phosphate in urea cycle, or passes through nitricoxide synthase (NOS) catalysis arginine generates NO accessory substance.First, arginine can be oxidized to N- hydroxyls-arginine, then row is oxidized to melon Propylhomoserin simultaneously disengages nitric oxide.
Appropriate citrulling and various vitamins can promote to increase energy, and maintain immune system.Citrulling helps body Body sets up and pressure, can also maintain body ph balancing.
Improve the motor function in Jiankang, citrulling can be acted on ammonia in human body, generation arginine and nitric oxide.One oxygen Change nitrogen energy activating enzyme, cause smooth muscle relaxation.It can also make the blood vessel of people be relaxed, and for strengthening function, contribute to Reproductive function.
Ginkgo (Ginkgo biloba L.)
Ginkgo is a kind of plant with very high medical value, and ginkgo is the ancient seeds of China, and it is magical doctor The tree for the treatment of, pre-Jurassic dinosaur controls terrestrial time within more than 200,000,000 5 thousand years, and ginkgo has been one of most flouring plant.Life on earth is gone through Through the variation of 100000000000 years, after the glacier covering of especially the 4th century, only ginkgo still kept the looks of its most original, in biology It is referred to as in evolutionism history " living fossil ".Its leaf, fruit, seed have higher medical value, and its pharmacological action is constantly recognized Know, clinical application range progressively expands.
The China in Recent Years academy of sciences and lot of domestic and foreign medical expert research are found：Kind more than 160 is can extract in ginkgo leaf to be had The medicinal ingredient of effect wherein, 35 kinds of flavone compound；17 kinds of amino acid and various trace elements
Ginkgo has anti-aging, improves immunity of organisms, strengthens a variety of functions such as resistance of human body.
Chinese cassia tree (Cortex Cinnamomi Cassiae)
Chinese cassia tree is the dry hide and branch skin in canella Chinese cassia tree and great Ye Qinghua osmanthus.Chinese cassia tree aiphyllium, is born in evergreen broad-leaved Lin Zhong, but be generally to cultivate.There is cultivation the torrid zone on the ground such as China Fujian, Taiwan, Guangdong, Guangxi, Yunnan and subtropical zone, especially It is many using Guangxi cultivation, is mostly Artificial Pure.
Effect of Chinese cassia tree and effect, Chinese cassia tree acrid-sweet flavor, property heat, enter kidney, spleen, bladder warp；There are complement sun, warming spleen and stomach, except product It is cold, effect of coronary circulation-promoting pain-relieving and antidiarrheal；Cure mainly the Yang-function insufficiency of kidneyzang, cold weak pulse of limb, yang depletion collapse, stomachache diarrhea, cold hernia, waist and knee cold Bitterly, the disease such as cloudy subcutaneous ulcer streamer, empty floating heat in the upper and cold in the lower more of sun.
Nutmeg (scientific name:Myristica fragrans)
For Myristica aiphyllium plant.Though it is spent and real shape is like in one's early teens, and skin and flesh is then different.Nutmeg is former Maluku is produced, torrid areas is cultivated extensively.
Nutmeg has the puckery intestines of middle benefit gas；Effect of promoting the circulation of qi helps digestion, usually does astringent medicinal, drugs for dispelling internal cold, qi-activating drug and uses.、 《Book on Chinese herbal medicine is through reading》Think that cold sperm can be controlled.《Book on Chinese herbal medicine asks former》The kidney type diarrhea, upper excess and lower deficiency, all inverse upper punchings, Yuanyang can be controlled by recording nutmeg Float and have a headache.
Sealwort (Polygonatum sibiricum Delar.ex Redonte)
Sealwort is the rhizome of liliaceous plant sealwort, David's-harp and P. kingianum, belongs to help quasi-tradition anti-aging guarantor Health food.This product is sweet mild-natured nontoxic, and return lung spleen kidney three is passed through, function nourishing Yin and moistening lung, invigorate the spleen and benefit qi, Zishen fill fine.
Sealwort contains a variety of steroidal soaps, Siberian solomonseal rhizome polysaccharide, digitalose and a small amount of green onionClass compound etc., with extension man Silkworm life cycle, confrontation radical damage, enhancing immunologic function, regulation second messenger's cycli phosphate gland (cAMP) level, enhancing cardiac muscle Convergent force, enhancing coronary blood flow, hypoglycemic, reducing blood lipid, antibacterial, antiviral, anti-width are penetrated, anti-mutation, sexual function regulation Deng effect.It is a kind of Chinese medicine for having a fine DEVELOPMENT PROSPECT.
Tribulus terrestris (Tribulus terrestris L.)
For the fruit of zygophyllaceae 1 year or herbaceos perennial puncture vine, the ground such as northeast, North China and northwest are mainly originated in. The fatty oil of tribulus terrestris, volatile oil, tannin, resin, sterol, sylvite, Alkaloid, saponin etc..Its water extract, ethanol are leached Liquid has antihypertensive effect to anesthetized animal；The thick saponin of puncture vine cauline leaf is stimulated by high temperature, low temperature, anoxic and Suppressor cells mouse There is obvious protective function：And significant vitamin C (Vc) content in adult rat adrenal tissue can be reduced, can also suppress heavy dose of hydrogenation can Pine caused by exhaust phenomenon, to caused by ACTH Vc contents decline shield.Cut off after mouse bilateral adrenal glands, Its resisting oxygen lack no longer reappears.These effects may be relevant with adrenal cortex, and it is probably real to adjust its function and exempt from exhaustion One of existing strong approach.Tribesta (preparation that puncture vine aerial part is made) gives male rat orally can obvious stimulation essence Son is formed, excited Sai Tuoli cells (Sertolicell) activity, increases sexual desire；Heat can then be promoted by giving female rats, be improved Fecundity.
Coix seed Coix lacryma-jobi L.var.ma-yuen Stapf)
For grass family Coix herbaceous plant, the benevolence of its drying and ripening is referred to as coix seed, stops with invigorating spleen to remove dampness, eliminating impediment Rush down, effect of clearing away heat and eliminating pus.Its main component includes coixenolide (coixenolide)；And fatty oil, oil in contain nutmeg Sour (myristic acid), campesterol (campesterol), palmitic acid, 8- octadecenic acids, stigmasterol etc., still containing amino Acid, protein, carbohydrate.Available for oedema, tinea pedis, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis, flat wart etc. Treatment.Modern pharmacology research shows, coix seed and its chemical active ingredient have it is antitumor, improve immunity, it is hypoglycemic Deng effect.
Matrimony vine (Lycium chinense Miller)
Matrimony vine is the plant of eggplant mesh Solanaceae Lycium (Lycium), and fruit claims the fruit of Chinese wolfberry, and tender leaf claims matrimony vine head, frequent species For matrimony vine, and main medical species are lycium barbarum (Lycium barbarum L.).Matrimony vine is born in ditch precipice and hillside or filling Irrigate field bund and water channel side etc..Wild and cultivation has.It is distributed mainly on the ground such as North China, northwest.Also there is cultivation in other areas.
The Tang Dynasty Lee stile《Elementary Medicine》In wuzi yanzong pills, exactly coordinate Semen Cuscutae etc. to make honeyed bolus with matrimony vine, with light Salt water delivery service, treatment impotence in male premature ejaculation, long infertility, poliosis and the small heeltap after an action of the bowels be can't help.The fruit of Chinese wolfberry is in enhancement work( There is unique effect in terms of energy, the well-known saying of " monarch's row a thousand li, do not eat matrimony vine " that folks of china spreads far and wide exactly says matrimony vine It is unsuitable to the youth man, the female that leave home with the very strong effect for exciting sexual function.But, for the men and women and Na being in For the people that a little sexual functions weaken, many food matrimony vines or its product are very important again.For the people of kidney deficiency, the fruit of Chinese wolfberry is undoubtedly It is most popular delicious food and panacea, even more a kind of rare health nutrient.
Barrenwort (Epimedium Maxim)
Barrenwort is also known as HERBA EPIMEDII, is the excessive sheep flower bud of Berberidaceae plant and the excessive sheep flower bud of Epimedium sagittatum, lobus cardiacus, korean epimedium herb Or the cauline leaf of E. Pubescens etc..This product work(arrogates to oneself tonifying kidney and strengthening yang, and ancients' meaning takes this product " it is negative and positive to make one ", and " western J is northern for cloud There is an excessive sheep, hundred times on the one conjunctions, caused by being apt to eat this leaves of pulse plants, therefore named barrenwort." illustrate that it has reliable tonifying kidney and strengthening yang to act on.All kidney yangs Deficiency, impotence is not lifted, sexual disorder person, with perseverance have good effect.
Modern pharmacological research shows that epimedium active constituent and its extract have extensive physiologically active, and find to be permitted More new pharmacological action and new application.Weight including increase testis and levator ani, plays androgen-like action, promotes dog sperm Secretion；Strengthen body non-specific immune function and cellular immune function, adjust humoral immune function；By influenceing Gegenbaur's cell Propagation, differentiation and mineralising promoting bone growing, and osteoclast number is reduced in vitro, weaken osteoclast absorption function；Substantially Strengthen the regulatory function of body Neuroendocrine net, body homeostasis is maintained, so that anti-aging.
Zinc citrate (Zinc citrate)
Zinc is necessary trace element in human body.About contain 2g zinc, most of distribution in microelement analyzer human body In bone, muscle, blood plasma and hair.The tissue of highest containing zinc is the visual component (containing 4%) and prostate of eyeball.Zinc is people The composition or coenzyme of the big enzyme of body six, 200 kinds of metalloenzyme, wide application is played to general metabolism.The enzyme containing zinc is (such as in human body Alkaline phosphatase needed for the carbonic anhydrase of oxygen therapy, bone growth) and the enzyme that is activated by zinc up to kind more than 70.Zinc participates in nucleic acid-protein The metabolic process of matter, can promote the normal development of skin, bone and sexual organ, maintain digestion and metabolic activity.Developmental youngster Apositia, nanism etc. can be caused during virgin zinc-deficiency, therefore, people call zinc " element of life ".
Embodiment 1
1 materials and methods
1.1 sample：
1.2 experimental animal：Kunming kind and ICR mouse, 18~22g of body weight, male and female half and half are tested dynamic by China Medicine University Thing room is provided.Childhood SD rat, is provided by Jiangsu Province's medical experiment animal center by 80-120 grams.
1.3 medicines and reagent:Ginseng, sealwort, maca, ginkgo, gumbo, Chinese cassia tree, nutmeg, coix seed, L-arginine, melon Propylhomoserin, barrenwort, tribulus terrestris, the fruit of Chinese wolfberry, zinc citrate, identify that medicinal material kind and quality are equal through institute of Chinese materia medica of University Of Suzhou Meet natural plants and food additives raw material requirement.Supplementary material by pulverizing and sieving → premix → essence is mixed → sieving → irradiation → Quality Control → packaging → preservation.Hydrocortisone acetate:The pharmaceutical factory of Shanghai the 9th produces, the testosterone of lot number 15 080 1. (T), Interstitialcellstimulating hormone (ICSH) (LH), flitropin (FSH) radioimmunoassay kitss, Tianjin Depew biotechnology and medical product have Limit company produces.Cortisol (F), which is put, exempts from box, China Atomic Energy Science Research Institute's Isotope production.
1.4 experimental method：
1.4.1 to the influence of normal mouse sexual organ and accessory sex organ's weight
CIR mouse are randomly divided into 5 groups, every group 10, health products C small dose groups, 400mg/kg, health products C middle dose groups, 800mg/kg, health products C heavy dose group, 1600mg/kg.Positive controls give methyltestosterone (3mg/kg), negative control group Give the physiological saline of equivalent 0.9%, the above-mentioned equal gastric infusion of each group, one time a day, continuous 10d.24 hours after last dose, take Relevant internal organs are weighed, and calculate its organ coefficient.Organ coefficient=organ weight/body weight.
1.4.2 the influence of hydrocortisone moulding male mice sexual organ and accessory sex organ's weight
Male Kunming strain mice, body weight 18-22g is randomly divided into 5 groups, respectively every group 10, normal group, mould by body weight Type group, positive controls and administration group (three groups of component of administration, small dose group gavage 400mg/kg health products C, middle dosage gavage 800mg/kg health products C, heavy dose fills 1600mg/kg health products C).Normal group, model control group gavage physiology salt Water 0.2mL/lOg, the next day 1 time, continuous 15 days.Normal group intramuscular injection physiological saline is removed daily, and other each groups are daily Intramuscular injection hydrocortisone 25mg/kg, causes syndrome of deficiency of kidney yang animal model.After last dose after 24 hours, take off cervical vertebra and put to death mouse, Thymus gland, spleen, adrenal gland, testis, epididymis are rapidly separated, seminal vesicle, preputial gland is taken and claims weight in wet base, calculate organ coefficient.
1.4.3 to the influence of childhood castrated rats accessory sex organ weight
To observe single composition in this health products and several into subassembly and 14 kinds of health products pair prepared into subassembly The influence of sexual function, this experiment is prepared for the single preparations of ephedrine based on this health products main component, and this health products is several main The composing prescription preparation of 14 component compositions of compound preparation and this health products of composition composition.Specific formula see the table below：
When being tested, castrated rats are randomly divided into 12 groups, Jinseng health-care food group, maca health food group, gumbo Health food group, Siberian solomonseal rhizome health-care food group, health food A groups, health food B groups, the large, medium and small dosage groups of health food C, sun Property control group, castration model group and Normal group, every group each 10.Every is administered daily：1) Normal group：Physiological saline is filled Stomach 0.2ml；2) castration model group, physiological saline gavage, 0.2ml；3) aqueous solution gavage is made in positive controls, methyltestosterone, 3mg/kg；4) the heavy dose of groups of health products C, 1600mg/kg, gavage；5) health products C middle dose groups, 800mg/kg, gavage；6) protect Strong product C small dose groups, 400mg/kg, gavage；7) health products A groups, 800mg/kg, gavage；8) health products B groups, 800mg/kg is filled Stomach；9) ginseng health product group, 400mg/kg, gavage；10) maca health products group, 1600mg/kg, gavage；11) healthcare okra product Group, 1600mg/kg, gavage；12) Siberian solomonseal rhizome health-care product group, 400mg/kg, gavage.Experimental method：After above-mentioned 12 groups of administrations 21 days, Electric stimulating instrument stimulating electrode is positioned over rat penis position and gives 4mA, the electro photoluminescence of 25V voltages, record since stimulating to The telotism time (erects incubation period, s).Next day claims animal body quality, plucks eyeball blood sampling, puts to death animal and wins preputial gland, essence Liquid capsule, prostate, musculus levator ani, hypophysis, adrenal gland, thymus gland, spleen electronic balance claim weight in wet base, calculate organ index (internal organ weight Amount<Weight)；Separate the content that serum presses serum measured by radioimmunoassay T, LH.FSH and F.MAIN OUTCOME MEASURES：1) to going The influence of gesture male rat telotism ability；2) to the influence of castrated rats accessory sex organ；3) to castrated rats hypophysis, chest Gland, adrenal gland, the influence of spleen；4) to the influence of sexual gland endocrine hormone.
Statistical analysis：Experimental data is handled with SSPE8.0 statistical softwares, is compared between group and is examined with t.
1.4.4 to infant rats, the influence of ICR mouse sperms
Infant rats, ICR mouse are respectively classified into control group, positive group and administration group, and (three groups of component of administration, health products C is small Dosage group, gavage, 400mg/kg, health products C middle dose groups, gavage, 800mg/kg health food, health products C heavy dose groups, Gavage, 1600mg/kg).Control group is to normal saline, and positive group gives methyltestosterone and aqueous solution gavage, 3mg/kg is made. Rat, mouse are administered 14 days, 10 days respectively, in after last dose 24, put to death animal, and rat and mouse take side epididymis, weighed, Normal saline dilution is used after homogenate, sperm count is counted.Take side highland ball simultaneously, plus few drops of 37 DEG C of physiological saline, quickly shred, take Suspension counts the percentage of sperm motility on slide under microscope.
2 results
The influence of 2.1 pairs of normal mouse sexual organs and accessory sex organ's weight
Table 1 is that sexual function adjusts influences of the health food C to normal mouse sexual organ and accessory sex organ's weight.
As can be seen from Table 1：Compared with control group, orally give after sexual function regulation health food C of the present invention, Positive controls and the weightening notable to mouse epididymis of each dosage administration group and in dose-effect dependence (* P<0 05；**P<0.01)； This health products C is big, middle dose group and positive controls can cause dramatically increasing for testicular weight, significant difference significantly (* P<0 05)；This health products C heavy dose groups can dramatically increase the weight (P of ovary<0 05), and significant difference is notable.
The influence of 2.2 hydrocortisone moulding male mice sexual organs and accessory sex organ's weight
Table 2 is that sexual function adjusts health food C to hydrocortisone moulding to mouse sexual organ and accessory sex organ's weight Influence.
As a result show, hydrogen may be such that male mice sexual organ, accessory sex organ and body weight all declines, wherein epididymis, preputial gland, Statistically significant (the * P of decline of prostate, adrenal gland and body weight<0 05；**P<0.01；***P<0.001).And this health products Large, medium and small metering group can substantially epididymis, preputial gland and Body weight loss significant differences be obvious caused by confrontation model groupThis health products C is big, middle dose group can substantially resist hydrogenation The decline of testis, prostate and adrenal gland weight caused by cortisone；This health products heavy dose group can substantially resist hydrogenation can The weight of seminal vesicle declines caused by loose, and significant difference is obviousFrom experimental result it is also seen that, experiment periods Between moulding group dead mouse 3 and administration group health products C small dose groups only dead 1, middle dosage and heavy dose are without death, explanation Health products C can reduce the weak death of mouse that hydrogen can be caused, show certain protective effect.
The influence of 2.3 pairs of childhood castrated rats accessory sex organ weight
Table 3 is influence of the different health foods to castration male rat telotism ability.
The result of table 3 shows that the incubation period of the electric stimulus inducing telotism of castration model group rats is bright compared with Normal group Aobvious extension (* P≤0.01；).The eclipse period of penile erection of health products C groups compares with castration model group, big, middle dose group and the positive Control group substantially shortens (* P≤0 05；**P≤0.01).Small dose group shortens incubation period of erecing, but no significant difference； Other each administration group eclipse period of penile erection compare with castration model group, and health products group has the reduction preclinical effect of penis, but Less, in its main component, content of the content than health products C of ginkgo biloba extract and Rhizoma Polygonati extract is added significant difference 5 times and 3 times, cinnamomum cassia extract is added more than 2 times.Health products group B groups can substantially shorten eclipse period of penile erection, significant difference (* P≤0 05), its main component and health products A ratios, eliminate ginseng, and lemon is acid, coix seed, tribulus terrestris extraction, Chinese cassia tree Extract, with the addition of maca, matrimony vine, citrulling and arginine；Compare with health products C, its main component has lacked ginseng, Job's tears Benevolence, lemon is acid, tribulus terrestris extraction, cinnamomum cassia extract and barrenwort；In folk prescription health products, gumbo, ginseng and sealwort are at it Added respectively in dose ratio health products C in the case of 7 times, 4 times and 7.5 times, there is shortening effect to eclipse period of penile erection, but Without significant difference, maca group can significantly reduce eclipse period of penile erection, significant difference (* P≤0 05), but its maca concentration ratio Health products C is added more than two times.
Table 4 is influence of the different health foods to accessory sex organ's weight.
The result of table 4 shows：Compare with Normal group, accessory sex organ's preputial gland of castration model group rats, levator ani, essence The organ index of liquid capsule-prostate substantially reduces (* * P≤0.01), compares with castration model group, health products C groups it is small, it is big or middle The organ index of the preputial gland of dosage group substantially increases (* P≤0 05), and dose-effect relationship is obvious.In, the levator ani of heavy dose group, The organ index of seminal fluid capsule-prostate also substantially increases, significant difference (* P≤0 05-**P≤0.01), there is dose-effect relationship.It is small Increase though dosage group has, no significant difference；Other each administration groups compare with castration model group, and health products A groups are without dirty Device index increases effect, and health products B groups can substantially increase the organ index of preputial gland and seminal vesicle-prostate, significant difference (* P ≤ 0.05), but to levator ani without effect.In the change of its main component, health products A groups ginkgo biloba extract and Rhizoma Polygonati extract contain Measure the content than health products C and add 5 times and 3 times, cinnamomum cassia extract is added more than 2 times, but no maca, matrimony vine, citrulling, The main components such as arginine.Health products B groups main component and health products A ratios, eliminate ginseng, and lemon is acid, and coix seed pierces puncture Lamb's-quarters extract, cinnamomum cassia extract with the addition of maca, matrimony vine, citrulling and arginine；Compare with health products C, its main component is few Ginseng, coix seed, lemon is acid, tribulus terrestris extraction, cinnamomum cassia extract and barrenwort；In folk prescription health products, in gumbo, people Added respectively in the case of 2 times, 7 times, 4 times and 7.5 times, to above-mentioned organ index in the dose ratio health products C of ginseng and sealwort Have and increase effect, but without significant difference (P >=0.05).Maca group can significantly increase each organ index, significant difference (* P≤0 , but its maca concentration ratio health products C is added more than two times 05).
Table 5 is influence of the different health products to organ weights such as hypophysis, adrenal gland, thymus gland and spleens
The result of table 5 shows, compares with Normal group, and the organ index of the hypophysis of castration model group reduces (P≤005)； The organ index increase (P≤0 01) of thymus gland；Adrenal organ index is reduced, the organ index increase of spleen, but difference without Significant.But compare with castration model group.Big, middle dose group hypophysis the organ index of health products C groups substantially increases (* P ≤0 05；* P≤0.01), dose-effect relationship is obvious.The adrenal organ index of heavy dose group substantially increases, but the internal organs of thymus gland Index is decreased obviously, significant difference (* * P≤0.01).In, small dose group health products C to adrenal gland, though thymus gland and spleen have shadow Ring, but no significant difference；Other each administration groups compare with castration model group, influence of the health products A groups to all internal organs The notable meaning of indifference, health products B groups can substantially increase the organ index of hypophysis, significant difference (* P≤0.05), but to other The significant meaning of influence indifference of internal organs..In the change of its main component, health products A groups ginkgo biloba extract and Rhizoma Polygonati extract Content of the content than health products C add 5 times and 3 times, cinnamomum cassia extract is added more than 2 times, but without maca, matrimony vine, melon Propylhomoserin, the main component such as arginine.Health products B groups main component and health products A ratios, eliminate ginseng, and lemon is acid, Job's tears Benevolence, tribulus terrestris extraction, cinnamomum cassia extract with the addition of maca, matrimony vine, citrulling and arginine；Compare with health products C, it is led Composition is wanted to lack ginseng, coix seed, lemon is acid, tribulus terrestris extraction, cinnamomum cassia extract and barrenwort；In folk prescription health products, In gumbo, added respectively in the case of 2 times, 7 times, 4 times and 7.5 times, to above-mentioned in the dose ratio health products C of ginseng and sealwort Organ index, which has, increases effect, but without significant difference (P >=0.05).Maca group maca concentration ratio health products C is added more than two times, Can significantly increase the organ index of hypophysis and thymus gland, significant difference (* P≤0 05), but to the exponential effects of other organs without Significant difference (P >=0.05).
Table is influence of the 6 different health products to castrated rats sexual gland endocrine hormone.
The result of table 6 shows, compares with Normal group, and the serum T of castration model group, F contents are reduced, but only T Significant difference has significant (* P≤0 05)；LH and FSH contents increase, but only FSH differences have significant (*P≤0 05).Compare with castration model group, this health products is big, the T of T, F and LH content of middle dose group and positive controls and F contents substantially increase, significant difference (* P≤0 05-**P≤0.01)；The FSH of this health products heavy dose group is containing reducing, and difference has Significant (* P≤0 05)；Influence of the low dose of health products C groups to individual endocrine hormone there was no significant difference (P >=0 05).There was no significant difference for influences of the middle dosage health products C to FSH (P >=0 05).Other each administration groups are with castration model group ratio Compared with health products A groups can substantially increase T's to the notable meaning of the influence indifference of all sexual glands and endocrine hormone, health products B groups Content, significant difference (* P≤0.05), but to the significant meaning of the influence indifference of its sexual gland and endocrine hormone.It is main in product Want in composition transfer, content of the content than health products C of health products A groups ginkgo biloba extract and Rhizoma Polygonati extract adds 5 times and 3 Times, cinnamomum cassia extract is added more than 2 times, but no maca, matrimony vine, citrulling, the main component such as arginine.Health products B groups are led Composition and health products A ratios are wanted, ginseng is eliminated, lemon is acid, and coix seed, tribulus terrestris extraction, cinnamomum cassia extract with the addition of agate Coffee, matrimony vine, citrulling and arginine；Compare with health products C, its main component has lacked ginseng, coix seed, lemon is acid, pierces puncture Lamb's-quarters extract, cinnamomum cassia extract and barrenwort；In folk prescription health products, in gumbo, divide in the dose ratio health products C of ginseng and sealwort Do not add in the case of 2 times, 7 times, 4 times and 7.5 times, the influence to above-mentioned sexual gland and endocrine hormone but without significant difference (P ≥0.05).Maca group maca concentration ratio health products C is added more than two times, can dramatically increase T and LH concentration, significant difference (* P≤0 05), but influence to other sexual glands and endocrine hormone is without significant difference (P >=0.05).
The influence of 2.4 pairs of infant rats and ICR mouse sperms
Table 7 is that sexual function adjusts influence of the health food to infant rats and ICR mouse sperms.
Compared with control group, the large, medium and small dosage group of this health products and positive controls can dramatically increase rat and The sperm quantity of ICR mouse, significant difference is significantly (P≤0 05-0.01).
Comprehensive Experiment result, this sexual function regulation health food that the present invention is provided has obvious enhancing to make to sexual function With.As a result show that this health food has substantially reduction castrated rats erection incubation period, increase erectile ability, increase mouse property Organ and the weight of accessory sex organ, hence it is evident that the effect of sexual gland and accessory sex organ's weight reduction caused by antagonism hydrocortisone；It is bright The weight of aobvious increase Rats after Castration accessory sex organ；And sperm quantity can be dramatically increased.This health products has to sexual function to be promoted Enter and adjustment effect, to clinical practice, this health products prevents and treats the diseases such as sexual dysfunction (impotence, sexual disorder) there is provided section Learn foundation,
Active compound and auxiliary material, preparation can be bought by market used in the sexual function regulation health food that the present invention is provided.
Animal experiment result confirm that this health food has obvious adjustment effect to sexual function, with nontoxicity, peace Entirely, it is orally available, the advantages of edible.
Present invention discover that this health food is positive in the functional check methods experiment that sexual function is adjusted, the present invention is provided This sexual function regulatory function can be applied to preparative function point analysis health products or food.
The specific research of this health food sexual function regulation, for confirming that the regulation of its sexual function and its healthcare function have existing Sincere justice and application value.
It is an advantage of the invention that：
1. safety, non-toxic, orally available.
2. the function of pair health food has done new exploration, fine supplement is done on the basis of its original knows function, it is found Sexual function adjustment effect.
3. a health food is oral or instant, there is conspicuousness function point analysis healthcare function, referrer is about with dosage Maca does not surpass 25 grams (60kg.BW) daily, and the daily consumption of ginseng is no more than 3 grams (60kg.BW).
Embodiment
With reference to embodiment, the invention will be further described.
Embodiment 1：
A kind of sexual function adjusts health food, and following components is configured by weight：
(gumbo extract:For pale yellow powder, extracted after the mixing of the root of okra, leaf, flower and seed, crushing.Mainly Extraction process：Clear water clean → increases water pulping → filter out residue → concentrate drying.The concentration of extract effective ingredient is 10%).
Sealwort：4 parts
Ginkgo biloba extract：1 part
(ginkgo biloba extract：For the powder of sundown to sepia.It is with ginkgo Ginkgo biloba L. Ye Weiyuan Material, using appropriate solvent, the effective component extracts of extraction.Main production flow is：Ginkgo leaf → clear water clean etc. Pre-treatment → alcohol extracting → recovery concentration → refined → spray drying.20%) extract effective ingredient concentration is.
Tribulus terrestris extraction：2 parts
(tribulus terrestris extraction：For brownish-yellow powder, main production flow is：Tribulus terrestris raw material → crushing → alcohol extracting → concentration → extraction → drying.Wherein 40%) saponin content is.
Cinnamomum cassia extract：3 parts
(cinnamomum cassia extract：For yellowish-brown powder, mainly from canella Chinese cassia tree Cinnamomum cassia Presl's The extract obtained in bark.Main production flow is：Selection → decoction → diacolation → backflow → distillation → precipitation → quiet → filtering → is put to concentrate → dry.15%) extract effective component content is.
Plus 2 parts of pharmaceutic adjuvant microcrystalline celluloses and 1 part of pharmaceutic adjuvant--magnesium stearate, it is made as tablet.
Supplementary material pulverizes and sieves to → premix → drying → whole grain of pelletizing → total mixed → tabletting → coating → inner packing → outer Bag → storage.
According to daily 1~2 time, the consumption of 100~2000mg/kg body weight every time, can also be produced as oral liquid, beverage, Capsule, spray or cutaneous permeable agent.
Embodiment 2：
A kind of sexual function adjusts health food, and following components is configured by weight：
(gumbo extract:For pale yellow powder, extracted after the mixing of the root of okra, leaf, flower and seed, crushing.Mainly Extraction process：Clear water clean → increases water pulping → filter out residue → concentrate drying.The concentration of extract effective ingredient is 10%).
Sealwort：10 parts
Ginkgo biloba extract：3 parts
(ginkgo biloba extract：For the powder of sundown to sepia.It is with ginkgo Ginkgo biloba L. Ye Weiyuan Material, using appropriate solvent, the effective component extracts of extraction.Main production flow is：Ginkgo leaf → clear water clean etc. Pre-treatment → alcohol extracting → recovery concentration → refined → spray drying.20%) extract effective ingredient concentration is.
Tribulus terrestris extraction：6 parts
(tribulus terrestris extraction：For brownish-yellow powder, main production flow is：Tribulus terrestris raw material → crushing → alcohol extracting → concentration → extraction → drying.Wherein 40%) saponin content is.
Cinnamomum cassia extract：7 parts
(cinnamomum cassia extract：For yellowish-brown powder, mainly from canella Chinese cassia tree Cinnamomum cassia Presl's The extract obtained in bark.Main production flow is：Selection → decoction → diacolation → backflow → distillation → precipitation → quiet → filtering → is put to concentrate → dry.15%) extract effective component content is.
Plus 2 parts of pharmaceutic adjuvant microcrystalline celluloses and 1 part of pharmaceutic adjuvant--magnesium stearate, it is made as tablet.
Supplementary material pulverizes and sieves to → premix → drying → whole grain of pelletizing → total mixed → tabletting → coating → inner packing → outer Bag → storage.
According to daily 1~2 time, the consumption of 100~2000mg/kg body weight every time, can also be produced as oral liquid, beverage, Capsule, spray or cutaneous permeable agent.
Embodiment 3：
A kind of sexual function adjusts health food, and following components is configured by weight：
(gumbo extract:For pale yellow powder, extracted after the mixing of the root of okra, leaf, flower and seed, crushing.Mainly Extraction process：Clear water clean → increases water pulping → filter out residue → concentrate drying.The concentration of extract effective ingredient is 10%).
Sealwort：8 parts
Ginkgo biloba extract：2 parts
(ginkgo biloba extract：For the powder of sundown to sepia.It is with ginkgo Ginkgo biloba L. Ye Weiyuan Material, using appropriate solvent, the effective component extracts of extraction.Main production flow is：Ginkgo leaf → clear water clean etc. Pre-treatment → alcohol extracting → recovery concentration → refined → spray drying.20%) extract effective ingredient concentration is.
Tribulus terrestris extraction：4 parts
(tribulus terrestris extraction：For brownish-yellow powder, main production flow is：Tribulus terrestris raw material → crushing → alcohol extracting → concentration → extraction → drying.Wherein 40%) saponin content is.
Cinnamomum cassia extract：5 parts
(cinnamomum cassia extract：For yellowish-brown powder, mainly from canella Chinese cassia tree Cinnamomum cassia Presl's The extract obtained in bark.Main production flow is：Selection → decoction → diacolation → backflow → distillation → precipitation → quiet → filtering → is put to concentrate → dry.15%) extract effective component content is.
Plus 2 parts of pharmaceutic adjuvant microcrystalline celluloses and 1 part of pharmaceutic adjuvant--magnesium stearate, it is made as tablet.
Supplementary material pulverizes and sieves to → premix → drying → whole grain of pelletizing → total mixed → tabletting → coating → inner packing → outer Bag → storage.
According to daily 1~2 time, the consumption of 100~2000mg/kg body weight every time, can also be produced as oral liquid, beverage, Capsule, spray or cutaneous permeable agent.
Finally it should be noted that foregoing description is only the preferred embodiments of the present invention, the ordinary skill people of this area Member on the premise of without prejudice to present inventive concept and claim, can make table as multiple types under the enlightenment of the present invention Show, such conversion is each fallen within protection scope of the present invention.

Claims (4)

1. a kind of sexual function adjusts health food, by weight comprising following components：
2. a kind of sexual function adjusts health food according to claim 1, it is characterised in that：The health food is also added with Pharmaceutic adjuvant.
3. a kind of sexual function adjusts health food according to claim 1, it is characterised in that：The health food is oral Liquid, beverage, tablet, capsule, spray or cutaneous permeable agent.
4. a kind of one kind sexual function regulation health food preparation method as described in claim 1-2, is carried out as follows：It is former auxiliary Material pulverize and sieve → premix → dryings → whole grain of pelletizing → always mix → tabletting → coating → inner packing → outsourcing → storage.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109602003A (en) * 2018-12-07 2019-04-12 入圣生物科技无锡有限公司 A kind of food and preparation method of adjustable vitality of human body and mood
CN110140960A (en) * 2019-06-03 2019-08-20 宝健（北京）生物技术有限公司 A kind of improvement male erectile dysfunction, antifatigue composition and preparation, drink
CN112868919A (en) * 2021-02-25 2021-06-01 新疆农业大学 Feed for improving quality of ram semen and application thereof
WO2021133285A1 (en) * 2019-12-25 2021-07-01 Melikoglu Ahmet A herbal performance enhancement mix and its production process

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Publication number Priority date Publication date Assignee Title
CN101933972A (en) * 2010-08-20 2011-01-05 王亭 Nitric oxide reinforcing agent and application thereof
CN104783177A (en) * 2015-03-19 2015-07-22 沈阳伊人宝生化制品有限公司 Maca preparation
CN106473099A (en) * 2016-10-12 2017-03-08 钟术光 Functional food or alternative tea that effect improves

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101933972A (en) * 2010-08-20 2011-01-05 王亭 Nitric oxide reinforcing agent and application thereof
CN104783177A (en) * 2015-03-19 2015-07-22 沈阳伊人宝生化制品有限公司 Maca preparation
CN106473099A (en) * 2016-10-12 2017-03-08 钟术光 Functional food or alternative tea that effect improves

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109602003A (en) * 2018-12-07 2019-04-12 入圣生物科技无锡有限公司 A kind of food and preparation method of adjustable vitality of human body and mood
CN110140960A (en) * 2019-06-03 2019-08-20 宝健（北京）生物技术有限公司 A kind of improvement male erectile dysfunction, antifatigue composition and preparation, drink
WO2021133285A1 (en) * 2019-12-25 2021-07-01 Melikoglu Ahmet A herbal performance enhancement mix and its production process
CN112868919A (en) * 2021-02-25 2021-06-01 新疆农业大学 Feed for improving quality of ram semen and application thereof
CN112868919B (en) * 2021-02-25 2023-01-17 新疆农业大学 Feed for improving quality of ram semen and application thereof

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