CN107011311A - 用于治疗HSP90相关病状的Pochoxime缀合物 - Google Patents

用于治疗HSP90相关病状的Pochoxime缀合物 Download PDF

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CN107011311A
CN107011311A CN201611152551.5A CN201611152551A CN107011311A CN 107011311 A CN107011311 A CN 107011311A CN 201611152551 A CN201611152551 A CN 201611152551A CN 107011311 A CN107011311 A CN 107011311A
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N.温辛格
S.巴鲁恩嘉
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NATIONAL CENTER FOR SCIENTIFIC RESEARCH
Universite de Strasbourg
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NATIONAL CENTER FOR SCIENTIFIC RESEARCH
Universite de Strasbourg
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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CN201611152551.5A 2010-10-22 2011-10-24 用于治疗HSP90相关病状的Pochoxime缀合物 Pending CN107011311A (zh)

Applications Claiming Priority (3)

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US40588210P 2010-10-22 2010-10-22
US61/405,882 2010-10-22
CN2011800601830A CN103370311A (zh) 2010-10-22 2011-10-24 用于治疗HSP90相关病状的Pochoxime缀合物

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CN107011311A true CN107011311A (zh) 2017-08-04

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CN201611152551.5A Pending CN107011311A (zh) 2010-10-22 2011-10-24 用于治疗HSP90相关病状的Pochoxime缀合物
CN2011800601830A Pending CN103370311A (zh) 2010-10-22 2011-10-24 用于治疗HSP90相关病状的Pochoxime缀合物

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US (3) US20140031302A1 (https=)
EP (1) EP2630132A1 (https=)
JP (2) JP2013543840A (https=)
KR (1) KR20140021520A (https=)
CN (2) CN107011311A (https=)
AU (1) AU2011319685B2 (https=)
BR (1) BR112013009614A2 (https=)
CA (1) CA2812320A1 (https=)
IL (1) IL225371A0 (https=)
RU (1) RU2013122898A (https=)
WO (1) WO2012052843A1 (https=)

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CN119424412A (zh) * 2024-12-04 2025-02-14 中国药科大学 以prdx1作为药物靶标的天然抑制剂在制备抗乳腺癌药物中的应用

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US20140079636A1 (en) 2012-04-16 2014-03-20 Dinesh U. Chimmanamada Targeted therapeutics
EP3035938B1 (en) * 2013-09-10 2020-08-19 Madrigal Pharmaceuticals, Inc. Targeted therapeutics
WO2015066053A2 (en) 2013-10-28 2015-05-07 Synta Pharmaceuticals Corp. Targeted therapeutics
WO2015116774A1 (en) 2014-01-29 2015-08-06 Synta Pharmaceuticals Corp. Targeted therapeutics
AU2015224576A1 (en) 2014-03-03 2016-09-22 Madrigal Pharmaceuticals, Inc. Targeted therapeutics
WO2015143004A1 (en) 2014-03-18 2015-09-24 Synta Pharmaceuticals Corp. Targeted therapeutics
WO2016126726A1 (en) 2015-02-02 2016-08-11 Forma Therapeutics, Inc. Bicyclic [4,6,0] hydroxamic acids as hdac6 inhibitors
SG11201708622UA (en) 2015-02-02 2017-11-29 Forma Therapeutics Inc 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
EP3472131B1 (en) 2016-06-17 2020-02-19 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as hdac inhibitors
CN110799194A (zh) 2017-06-20 2020-02-14 马德里加尔制药公司 包含靶向治疗剂的联合疗法
EP3641647A4 (en) 2017-06-20 2021-05-05 Madrigal Pharmaceuticals, Inc. TARGETED THERAPEUTICS
WO2022082108A1 (en) * 2020-10-16 2022-04-21 The Brigham And Women's Hospital, Inc. Compositions for inducing tumor immunity and reducing drug tolerance

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WO2009091921A1 (en) * 2008-01-15 2009-07-23 Universite De Strasbourg Synthesis of resorcylic acid lactones useful as therapeutic agents
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WO2009091921A1 (en) * 2008-01-15 2009-07-23 Universite De Strasbourg Synthesis of resorcylic acid lactones useful as therapeutic agents
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CA2812320A1 (en) 2012-04-26
RU2013122898A (ru) 2014-11-27
WO2012052843A1 (en) 2012-04-26
AU2011319685B2 (en) 2016-02-04
CN103370311A (zh) 2013-10-23
IL225371A0 (en) 2013-06-27
KR20140021520A (ko) 2014-02-20
AU2011319685A1 (en) 2013-04-11
BR112013009614A2 (pt) 2016-07-19
JP2017039730A (ja) 2017-02-23
EP2630132A1 (en) 2013-08-28
JP2013543840A (ja) 2013-12-09
US20170174669A1 (en) 2017-06-22
US20140031302A1 (en) 2014-01-30
US20150374680A1 (en) 2015-12-31

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Application publication date: 20170804