CN106974833A - A kind of preforming device of tablet medicine - Google Patents
A kind of preforming device of tablet medicine Download PDFInfo
- Publication number
- CN106974833A CN106974833A CN201710148891.9A CN201710148891A CN106974833A CN 106974833 A CN106974833 A CN 106974833A CN 201710148891 A CN201710148891 A CN 201710148891A CN 106974833 A CN106974833 A CN 106974833A
- Authority
- CN
- China
- Prior art keywords
- compacting platform
- platform
- compacting
- preforming device
- upper pressure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 28
- 230000007246 mechanism Effects 0.000 claims abstract description 15
- 238000003825 pressing Methods 0.000 claims abstract description 12
- 238000004826 seaming Methods 0.000 claims abstract description 10
- 230000008520 organization Effects 0.000 claims abstract description 7
- 230000006835 compression Effects 0.000 claims description 14
- 238000007906 compression Methods 0.000 claims description 14
- 229940079593 drug Drugs 0.000 claims description 10
- 238000003860 storage Methods 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 claims description 5
- 238000010276 construction Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008450 motivation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Basic Packing Technique (AREA)
Abstract
The invention discloses a kind of preforming device of tablet medicine, it includes frame, and upper rack is provided with compacting platform, and compacting platform upper is provided with tablet press mechanism, controlling organization and feeding machanism；Frame includes four columns be arrangeding in parallel, compacting platform is fixedly installed on the upper end of column, the periphery of compacting platform is provided with coaming plate, the bottom of compacting platform is provided with electric rotating machine, the output shaft of electric rotating machine is connected with driving wheel, driving wheel is connected by timing belt with driven pulley, rotating shaft of the driven pulley with suppressing Platform center is fixedly connected, rotating shaft top is fixed with guide rod, guide rod is located at the top of compacting platform, and guide rod top is fixedly installed seaming chuck, template and push-down head successively from top to bottom.The present invention is simple in construction, and it can realize the compacting to medicine in template using seaming chuck and push-down head, and operating process is simple, it is easy to carry out pressing operation.
Description
Technical field：
The present invention relates to pharmaceutical equipment technical field, and in particular to a kind of preforming device of tablet medicine.
Background technology：
In pharmaceutical field, many medicines are sale to be carried out in the form of tablet and oral, and this is accomplished by pharmaceutical manufacturing
During drug powder or particle is tabletted, and then stored, sold and taken.During tabletting, tabletting
Machine is one of indispensable equipment, and it can be suppressed original powder or particle by pressure effect, be finally given
Medicinal tablet.Existing tablet press machine is complicated, and operating process is cumbersome, and automaticity is than relatively low, and tabletting efficiency also compares
It is low, a kind of high preforming device of simple in construction, automaticity how is designed, is the technical barrier of this area.
The content of the invention：
There is provided a kind of preforming device of tablet medicine aiming at the deficiencies in the prior art for the purpose of the present invention.
To achieve the above object, technology solution of the invention is as follows：
A kind of preforming device of tablet medicine, it includes frame, and upper rack is provided with compacting platform, suppresses platform upper
It is provided with tablet press mechanism, controlling organization and feeding machanism；Frame includes four columns be arrangeding in parallel, and compacting platform, which is fixed, to be set
Put in the upper end of column, the periphery of compacting platform is provided with coaming plate, and the bottom of compacting platform is provided with electric rotating machine, electric rotating machine
Output shaft be connected with driving wheel, driving wheel is connected by timing belt with driven pulley, driven pulley with compacting Platform center rotating shaft
Be fixedly connected, rotating shaft top is fixed with guide rod, guide rod is located at the top of compacting platform, and guide rod top from top to bottom according to
It is secondary to be fixedly installed seaming chuck, template and push-down head；Seaming chuck includes being provided with multiple upper pressure groups on upper disk, upper disk
Part, upper pressure component is arranged on the outward flange of disk, and upper pressure component includes upper pressure seat, and upper pressure seat top is provided with pressure roller, on
The bottom of wedge is provided with upperpush rod, and compression spring is connected between upper pressure seat and upper disk；Template includes intermediate disc, in
Between be provided with multiple equally distributed drug storage chambers on disk；Push-down head includes lower disc, is provided with lower disc and multiple pushes group
Part, pushing component includes down pressing seat, and down pressing seat top is provided with lower compression roller, and the bottom of down pressing seat is provided with down-pressed pole, down pressing seat
Lower compression spring is connected between lower disc；Compacting platform two sides are fixedly installed support bar, and support bar top is provided with
Roller is provided with the rotating shaft of liftable regulation, rotating shaft, roller is located on the mobile route of upper pressure roller；Also set up on compacting platform
There is first annular raised and the second annular protrusion, first annular raised and the second annular protrusion is located at the mobile route of lower compression roller
On, it is first annular raised immediately below roller；Suppress flat edge of table and be additionally provided with support, support and be fixed with feeding machine
Structure, the periphery of feeding machanism is provided with vibrator, and the bottom discharge nozzle of feeding machanism is mutually connected with the drug storage chamber in template.
Feeding machanism is feed silo, and its upper and lower part is provided with level sensor, level sensor and alarm
Electrical connection.
Coaming plate is fixed on the outside of support column, and opens to unload with support column and be connected.
Be provided with compacting platform release the button, speed governing button and alarm, release the button, speed governing button and alarm
Device is electrically connected with controlling organization.
The bottom of adjacent upright posts is connected with crossbeam, and the bottom of column is provided with road wheel.
The top of adjacent upright posts is connected with upper junction plate, and upper junction plate is fixedly connected by weldment with column.
Road wheel drives via ground drive mechanism, and ground drive mechanism includes motor and transmission mechanism, passes
The output shaft connection of motivation structure and motor, and drive road wheel to walk.
The beneficial effects of the present invention are：The present invention is simple in construction, and it can be realized to mould using seaming chuck and push-down head
The compacting of medicine on plate, operating process is simple, it is easy to carry out pressing operation.
Brief description of the drawings：
Fig. 1 is structural representation of the invention；
Fig. 2 is the structural representation of compacting platform；
Fig. 3 is the side view of compacting platform；
Fig. 4 is the first annular raised structural representation with the second annular protrusion.
Embodiment：
In order that the above objects, features and advantages of the present invention can be more obvious understandable, below in conjunction with the accompanying drawings to this hair
Bright embodiment is described in detail.
As Figure 1-4, a kind of preforming device of tablet medicine, it includes frame, and upper rack is provided with compacting platform
12, compacting platform 12 top is provided with tablet press mechanism, controlling organization and feeding machanism；Frame include four be arranged in parallel it is vertical
Post 11, compacting platform 12 is fixedly installed on the upper end of column 11, and the periphery of compacting platform 12 is provided with coaming plate 14, suppresses platform 12
Bottom be provided with electric rotating machine 20, the output shaft of electric rotating machine 20 is connected with driving wheel, driving wheel by timing belt with it is driven
Wheel connection, driven pulley is fixedly connected with the rotating shaft 301 at compacting platform 12 center, and the top of rotating shaft 301 is fixed with guide rod 30, is oriented to
Bar 30 is located at the top of compacting platform 12, and the top of guide rod 30 is fixedly installed seaming chuck 31, template 32 successively from top to bottom
And push-down head 33；Seaming chuck 31 includes being provided with multiple upper pressure components 41 on upper disk, upper disk, and upper pressure component 41 is arranged on
The outward flange of upper disk, upper pressure component 41 includes upper pressure seat, and upper pressure seat top is provided with pressure roller 411, and the bottom of upper pressure seat is set
Upperpush rod 412 is equipped with, compression spring is connected between upper pressure seat and upper disk；Template 32 includes intermediate disc, intermediate disc
On be provided with multiple equally distributed drug storage chambers；Push-down head 33 includes lower disc, be provided with lower disc it is multiple push component 43,
Pushing component 43 includes down pressing seat, and down pressing seat top is provided with lower compression roller 431, and the bottom of down pressing seat is provided with down-pressed pole 432, under
Lower compression spring is connected between wedge and lower disc；Compacting platform 12 two sides are fixedly installed support bar 13, support bar 13
Top, which is provided with the rotating shaft 131 of liftable regulation, rotating shaft 131, is provided with roller 132, and roller 132 is located at the shifting of upper pressure roller 411
On dynamic path；First annular raised 51 and second annular protrusion 52, first annular raised 51 He are additionally provided with compacting platform 12
Second annular protrusion 52 is located on the mobile route of lower compression roller 431, and first annular raised 51 are located at immediately below roller 132；Compacting
The edge of platform 12 is additionally provided with support 15, support 15 and is fixed with feeding machanism 16, and the periphery of feeding machanism 16, which is provided with, to shake
Dynamic device 151, the bottom discharge nozzle 161 of feeding machanism 16 is mutually connected with the drug storage chamber in template 32.
First annular raised 51 height is less than the height of the second annular protrusion 52.
Feeding machanism 16 is feed silo, and its upper and lower part is provided with level sensor, level sensor and alarm
Device is electrically connected.
Coaming plate 14 is fixed on the outside of support column 13, and opens to unload with support column 13 and be connected.
Release the button 121, speed governing button 122 and alarm are provided with compacting platform 12,121, speed governing of releasing the button
Button 122 and alarm are electrically connected with controlling organization.
The bottom of adjacent upright posts 11 is connected with crossbeam 10, and the bottom of column 11 is provided with road wheel 101.
The top of adjacent upright posts 11 is connected with upper junction plate 111, and upper junction plate 111 is fixed by weldment and column 11 to be connected
Connect.
Road wheel 101 drives via ground drive mechanism, and ground drive mechanism includes motor and transmission mechanism,
The output shaft connection of transmission mechanism and motor, and drive road wheel 101 to walk.
The course of work：Press and release the button, electric rotating machine drives seaming chuck 31, template 32 and push-down head 33 to rotate, together
When feeding machanism supply medicine to the drug storage intracavitary of template, when roller is contacted and pressurizeed with upper pressure roller, lower compression roller is located exactly at first
On annular protrusion, i.e., upperpush rod and down-pressed pole are relatively moved, and the medicine of drug storage intracavitary are suppressed, with the fortune of electric rotating machine
OK, compacting is completed one by one, is that down-pressed pole ejects the tablet after compacting, by feeding when lower compression roller is located on the second annular protrusion
Mechanism takes away, completes the tabletting work of tablet.
The embodiment is to the illustrative present invention, not for the limitation present invention.Any those skilled in the art
The embodiment can be modified under the spirit and scope without prejudice to the present invention, therefore the rights protection model of the present invention
Enclose, should be as listed by the claim of the present invention.
Claims (7)
1. a kind of preforming device of tablet medicine, it is characterised in that：It includes frame, and upper rack is provided with compacting platform
(12), compacting platform (12) top is provided with tablet press mechanism, controlling organization and feeding machanism；Frame be arranged in parallel including four
Column (11), compacting platform (12) is fixedly installed on the upper ends of column (11), and the periphery of compacting platform (12) is provided with coaming plate
(14), the bottom of compacting platform (12) is provided with electric rotating machine (20), and the output shaft of electric rotating machine (20) is connected with driving wheel, main
Driving wheel is connected by timing belt with driven pulley, and rotating shaft (301) of the driven pulley with suppressing platform (12) center is fixedly connected, rotating shaft
(301) top is fixed with guide rod (30), and guide rod (30) is located at the top of compacting platform (12), and guide rod (30) top from
Seaming chuck (31), template (32) and push-down head (33) are fixedly installed under up to successively；Seaming chuck (31) includes upper disk, on
Multiple upper pressure components (41) are provided with disk, upper pressure component (41) is arranged on the outward flange of disk, upper pressure component (41) bag
Include upper pressure seat, upper pressure seat top is provided with pressure roller (411), the bottom of upper pressure seat is provided with upperpush rod (412), upper pressure seat with it is upper
Compression spring is connected between disk；Template (32) includes intermediate disc, is provided with intermediate disc multiple equally distributed
Drug storage chamber；Push-down head (33) includes lower disc, be provided with lower disc it is multiple push component (43), push under component (43) includes
Wedge, down pressing seat top is provided with lower compression roller (431), and the bottom of down pressing seat is provided with down-pressed pole (432), down pressing seat and lower disc
Between be connected with lower compression spring；Compacting platform (12) two sides are fixedly installed support bar (13), and support bar (13) top is set
It is equipped with the rotating shaft (131) of liftable regulation, rotating shaft (131) and is provided with roller (132), roller (132) is located at upper pressure roller (411)
Mobile route on；First annular raised (51) and the second annular protrusion (52), the first ring are additionally provided with compacting platform (12)
Shape projection (51) and the second annular protrusion (52) are located on the mobile route of lower compression roller (431), and first annular projection (51) is located at
Immediately below roller (132)；The edge of compacting platform (12) is additionally provided with support (15), and support is fixed with feeding machanism on (15)
(16), the periphery of feeding machanism (16) is provided with vibrator (151), the bottom discharge nozzle (161) and template of feeding machanism (16)
(32) the drug storage chamber on is mutually connected.
2. a kind of preforming device of tablet medicine according to claim 1, it is characterised in that：Feeding machanism (16) is feed
Silo, its upper and lower part is provided with level sensor, and level sensor is electrically connected with alarm.
3. a kind of preforming device of tablet medicine according to claim 1, it is characterised in that：Coaming plate (14) is fixed on support
The outside of post (13), and open to unload with support column (13) and be connected.
4. a kind of preforming device of tablet medicine according to claim 1, it is characterised in that：Suppress and set on platform (12)
Release the button (121), speed governing button (122) and alarm, release the button (121), speed governing button (122) and alarm
Electrically connected with controlling organization.
5. a kind of preforming device of tablet medicine according to claim 1, it is characterised in that：The bottom of adjacent upright posts (11)
Crossbeam (10) is connected with, the bottom of column (11) is provided with road wheel (101).
6. a kind of preforming device of tablet medicine according to claim 1, it is characterised in that：The top of adjacent upright posts (11)
Upper junction plate (111) is connected with, upper junction plate (111) is fixedly connected by weldment with column (11).
7. a kind of preforming device of tablet medicine according to claim 5, it is characterised in that：Road wheel (101) is via row
Walk actuation driving, ground drive mechanism includes motor and transmission mechanism, transmission mechanism and motor it is defeated
Shaft is connected, and drives road wheel (101) to walk.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710148891.9A CN106974833B (en) | 2017-03-14 | 2017-03-14 | Tablet pressing device for tablet medicines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710148891.9A CN106974833B (en) | 2017-03-14 | 2017-03-14 | Tablet pressing device for tablet medicines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106974833A true CN106974833A (en) | 2017-07-25 |
| CN106974833B CN106974833B (en) | 2020-03-10 |
Family
ID=59339489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710148891.9A Expired - Fee Related CN106974833B (en) | 2017-03-14 | 2017-03-14 | Tablet pressing device for tablet medicines |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106974833B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110000827A (en) * | 2019-04-16 | 2019-07-12 | 江苏信息职业技术学院 | A kind of fruits and vegetables auto slice device |
| CN110774648A (en) * | 2019-11-08 | 2020-02-11 | 合肥一枫医药有限公司 | Chinese herbal medicine decoction piece pressing method |
| CN110884196A (en) * | 2019-10-28 | 2020-03-17 | 广东新乐食品有限公司 | Automatic tabletting and forming device and method for double-layer tabletted sugar |
| CN111544298A (en) * | 2020-06-10 | 2020-08-18 | 湖南春光九汇现代中药有限公司 | Formula particle production device and use method thereof |
| CN111838380A (en) * | 2020-07-30 | 2020-10-30 | 湖南芳维食品有限公司 | A tablet press that is used for having dust collection structure of candy production |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1668439A (en) * | 2002-07-19 | 2005-09-14 | Smi有限公司 | Method and apparatus for making miniature tablets |
| CN102241158A (en) * | 2011-05-23 | 2011-11-16 | 苏光宝 | Automatic powder adding device of plastic powder molding machine |
| CN202573048U (en) * | 2012-06-06 | 2012-12-05 | 江门瑞怡乐甜味剂厂有限公司 | Multi-head pressing-sheet type full-automatic high-efficiency rotary preforming press |
| CN205339583U (en) * | 2016-01-26 | 2016-06-29 | 郑伟杰 | A novel rotary preforming press for production of pharmaceuticals |
| CN106142637A (en) * | 2016-08-30 | 2016-11-23 | 福建南安市华天机械有限公司 | A kind of automatic Powder forming press |
| CN205705428U (en) * | 2016-06-21 | 2016-11-23 | 北京新龙立科技有限公司 | A kind of operating console device of tablet machine |
-
2017
- 2017-03-14 CN CN201710148891.9A patent/CN106974833B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1668439A (en) * | 2002-07-19 | 2005-09-14 | Smi有限公司 | Method and apparatus for making miniature tablets |
| CN102241158A (en) * | 2011-05-23 | 2011-11-16 | 苏光宝 | Automatic powder adding device of plastic powder molding machine |
| CN202573048U (en) * | 2012-06-06 | 2012-12-05 | 江门瑞怡乐甜味剂厂有限公司 | Multi-head pressing-sheet type full-automatic high-efficiency rotary preforming press |
| CN205339583U (en) * | 2016-01-26 | 2016-06-29 | 郑伟杰 | A novel rotary preforming press for production of pharmaceuticals |
| CN205705428U (en) * | 2016-06-21 | 2016-11-23 | 北京新龙立科技有限公司 | A kind of operating console device of tablet machine |
| CN106142637A (en) * | 2016-08-30 | 2016-11-23 | 福建南安市华天机械有限公司 | A kind of automatic Powder forming press |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110000827A (en) * | 2019-04-16 | 2019-07-12 | 江苏信息职业技术学院 | A kind of fruits and vegetables auto slice device |
| CN110884196A (en) * | 2019-10-28 | 2020-03-17 | 广东新乐食品有限公司 | Automatic tabletting and forming device and method for double-layer tabletted sugar |
| CN110774648A (en) * | 2019-11-08 | 2020-02-11 | 合肥一枫医药有限公司 | Chinese herbal medicine decoction piece pressing method |
| CN110774648B (en) * | 2019-11-08 | 2021-06-29 | 安徽亳药千草中药饮片有限公司 | Chinese herbal medicine decoction piece pressing method |
| CN111544298A (en) * | 2020-06-10 | 2020-08-18 | 湖南春光九汇现代中药有限公司 | Formula particle production device and use method thereof |
| CN111838380A (en) * | 2020-07-30 | 2020-10-30 | 湖南芳维食品有限公司 | A tablet press that is used for having dust collection structure of candy production |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106974833B (en) | 2020-03-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106974833A (en) | A kind of preforming device of tablet medicine | |
| CN206840808U (en) | Disjunctor renovates medicine box automatic moulding machine | |
| CN103928374A (en) | Automation device and method for manufacturing sensor | |
| CN204846396U (en) | Carousel formula filter core packaging machine | |
| CN103612794A (en) | Granule counting machine | |
| CN104973271B (en) | Rotating disc type filter core sealing machine | |
| CN102430742B (en) | Casting die | |
| CN216804542U (en) | Anti-fragmentation traditional Chinese medicine decoction piece tabletting forming device | |
| CN208086132U (en) | A kind of capsule turns around device | |
| CN112050694B (en) | High-precision quantitative automatic explosive charging device for ignition powder box type initiating explosive device | |
| CN213353669U (en) | Tablet pressing machine | |
| CN108082574A (en) | A kind of capsule turns around device | |
| CN111544301A (en) | Rotary table of capsule filling machine | |
| CN215704392U (en) | Forming device for solid medicine | |
| CN212651087U (en) | Rotary table of capsule filling machine | |
| CN104309825A (en) | Granular capsule packaging machine | |
| CN108790256A (en) | A kind of novel pharmaceutical purpose tablet press machine | |
| CN108212683B (en) | Production equipment for refrigerant sealing cover | |
| CN206544610U (en) | A kind of medicine pill packing machine | |
| JP2008308204A (en) | Movement control device for nozzle and filling funnel in packaging machine | |
| CN104983574A (en) | Filling machine for water-honeyed pills | |
| CN206704650U (en) | A kind of decoction canning line send bottle | |
| CN206510469U (en) | A kind of magnet ring powder compacting equipment | |
| CN206187374U (en) | Perpendicular spiral packagine machine | |
| CN218617418U (en) | Oblique rotating feeding device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Dongping Inventor after: Li Wen Inventor after: Yu Zhanying Inventor after: Gao Yang Inventor before: Gao Yang |
|
| CB03 | Change of inventor or designer information | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20200117 Address after: 266555 Huangpu Road, Huangdao District, Shandong, Qingdao, 9 Applicant after: Qingdao Huangdao District Central Hospital Address before: Dongcheng District Guangming Road 523000 Guangdong city of Dongguan province No. 27 thousand Xu building room 436 Applicant before: DONGGUAN QINZHI INDUSTRIAL DESIGN CO., LTD. |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200310 Termination date: 20210314 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |