CN106822638A - 一种可有效治疗便秘的丸剂药物及其制备方法 - Google Patents
一种可有效治疗便秘的丸剂药物及其制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗便秘的认识机理而提供的一种可有效治疗便秘的丸剂药物,所述药物的各个组分及其质量份比如下:竹茹95g、生地黄280g、山楂115g、木香120g、厚朴95g、红花95g、桃仁120g、槟榔120g、生首乌200g、太子参280g、广陈皮80g、阿胶95g、当归130g、肉苁蓉120g、黑芝麻120g、桑葚130g、麦冬120g等;本发明提供的药物是一个很好的中药组方。
Description
一种可有效治疗便秘的丸剂药物及其制备方法
技术领域
[0001] 本发明属于中药制剂领域,具体涉及一种可有效治疗便秘的丸剂药物,特别是供 便秘患者使用的丸剂药物及其制备方法的领域。
背景技术
[0002]医者认为:便秘是临床常见的复杂症状,而不是一种疾病,主要是指排便次数减 少、粪便量减少、粪便干结、排便费力等。必须结合粪便的性状、本人平时排便习惯和排便有 无困难作出有无便秘的判断。如超过6个月即为慢性便秘。
[0003] 临床表现: 便秘在人群中的患病率高达27%,但只有一小部分便秘者会就诊。便秘可以影响各年龄 段的人。女性多于男性,老年多于青、壮年。因便秘发病率高、病因复杂,患者常有许多苦恼, 便秘严重时会影响生活质量。
[0004] 便秘常表现为:便意少,便次也少;排便艰难、费力;排便不畅;大便干结、硬便,排 便不净感;便秘伴有腹痛或腹部不适。部分患者还伴有失眠、烦躁、多梦、抑郁、焦虑等精神 心理障碍。
[0005]由于便秘是一种较为普遍的症状,症状轻重不一,大部分人常常不去特殊理会,认 为便秘不是病,不用治疗,但实际上便秘的危害很大。便秘的“报警,,征象包括便血、贫血、消 瘦、发热、黑便、腹痛等和肿瘤家族史。如果出现报警征象应马上去医院就诊,作进一步检 查。
[0006] 那么,就如何找到一种可有效治疗便秘的中药组合物,是本领域技术人员亟待要 解决的问题。
发明内容
[0007]随着我国中医中药学的不断发展,在治疗便秘上,人们逐渐意识到了中医治疗便 秘的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗便秘的 现状,本发明的目的是在于提供一种可有效治疗便秘的丸剂药物,以解决便秘患者早日恢 复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治 疗上述便秘。
[0008]为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗便秘 的汤剂药物及制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示: 竹茹50〜120g、生地黄100〜380g、山楂90〜150g、木香80〜160g、厚朴30〜120g、红花 3〇〜l2〇g、桃仁8〇〜l6〇g、槟榔㈤〜l6〇g、生首乌1〇〇〜26〇g、太子参100〜36〇g、广陈皮3〇 〜100g、阿胶3〇〜l2〇g、当归SO—iSOg、肉苁蓉1〇〇〜16〇g、黑芝麻9〇〜16〇g、桑葚9〇〜18〇g、 麦冬60〜160g,淀粉适量。 、
[0009] 一种可有效治疗便秘的丸剂药物及其制备方法,其特征在于,所述药物的各个组 分及其质量份比如下所示: 竹如58〜105g、生地黄115〜330g、山楂100〜i3〇g、木香90〜140g、厚朴36〜105g、红花 38〜l〇5g、桃仁9〇〜l4〇g、槟榔7〇〜14〇g、生首乌115〜230g、太子参115〜310g、广陈皮38 〜9〇g、阿胶38〜l〇5g、当归9〇〜l5〇g、肉苁蓉IIS〜14〇g、黑芝麻1〇〇〜I40g、桑葚100〜 l5〇g、麦冬70〜140g,淀粉适量。
[0010] 一种可有效治疗便秘的丸剂药物及其制备方法,其特征在于,所述“最佳方案”的 药物的各个组分及其质量份比如下所示: 竹茹95g、生地黄280g、山楂11叱、木香120g、厚朴95g、红花95g、桃仁120g、槟榔120g、生 首乌200g、太子参280g、广陈皮SOg、阿胶95g、当归130g、肉苁蓉120g、黑芝麻120g、桑葚 13(^、麦冬12(^,淀粉适量。
[0011] 一种可有效治疗便秘的丸剂药物及其制备方法,其特征在于,所述方法包括如下 步骤制备而成: A、 除淀粉外,将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待 用; B、 按照传统制备中药水丸剂的方法,将研磨好的极细末药物和淀粉过筛后,放入药器 中混合拌均,然后制备成水丸剂(其水丸的粒度为:3.8mm〜4.0mm),进而烘干、消毒,分装密 封即可。
[0012] —种可有效治疗便秘的丸剂药物及其制备方法,其特征在于,所述服用方法为:将 制备好的水丸剂药物以每日二次服用,早晚各服一次,给药量6g /次,温开水送服,服药2〜 3天后,症状消失,病获痊愈。
[0013] 本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记 载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效: 竹茹,性味:甘、微寒,具有清热化痰、除烦止呕、安胎凉血之功效,用于治疗肺热咳嗽、 烦热惊悸、胃热呕呃、妊娠恶阻、胎动不安、吐血、衄血、尿血、崩漏等症; 生地黄,性味:味甘、苦、性寒,具有清热、凉血之功效,用于治疗温热病热入营血、壮热 神昏、口干舌绛; 山楂,性味:酸、甘、微温,具有消食健胃、行气散瘀之功效,用于治疗肉食积滞、胃脘胀 满、泻痢腹痛、瘀血经闭、产后瘀阻、心腹刺痛、疝气疼痛、高脂血症;焦山楂消食导滞作用增 强,用于肉食积滞、泻痢不爽; 木香,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于 治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、症瘕积聚、热痹肿痛、跌打损伤、 热入营血、烦躁不安、心烦失眠、痈疮肿毒; 厚朴,性味:苦、辛、温,具有燥湿消痰、下气除满之功效,用于治疗湿阻中焦,脘腹胀 满,食积气滞,腹胀便秘,痰饮喘咳;此外,七情郁结,痰气互阻,咽中如有物阻,咽之不下, 吐之不出的梅核气证,亦可取本品燥湿消痰,下气宽中之效; 红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀 阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症; 桃仁,性味:苦甘、平,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、癥瘕、热病蓄血、 风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘; 槟榔,性味:味苦、辛、性温,具有驱虫、消积、下气、行水、截疟之功效,用于治疗虫积、食 滞、脘腹胀痛、泻痢后重、脚气、水肿、疟疾; 生首乌,性味:苦、甘、涩,具有补益肝肾、益精血、壮筋骨之功效,用于治疗瘰疬疮痈、风 疹瘙痒、肠燥便秘,制首乌功能补益精血、乌须发、强筋骨、补肝肾; 太子参,性味:甘、微苦、平,具有益气健脾、生津润肺之功效,用于治疗脾虚体倦、食欲 不振、病后虚弱、气阴不足、自汗口渴、肺燥干咳; 广陈皮,性味:苦、辛、温,具有理气健脾,燥湿化痰之功效,用于治疗胸脘胀满、食少吐 泻、咳嗽痰多; 阿胶,性味:甘、平,具有补血滋阴、润燥、止血之功效,用于治疗血虚萎黄、眩晕心悸、肌 痿无力、心烦不眠、虚风内动、肺燥咳嗽、劳嗽咯血、吐血尿血、便血崩漏、妊娠胎漏; 当归,性味:味甘、辛、微苦、性温,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗 月经不调、经闭腹痛、癥瘕结聚、崩漏、血虚头痛、眩晕、痿痹,肠燥便难、赤痢后重,痈疽疮 窃、跌扑损伤等症; 肉苁蓉,性味:味甘、咸、性温,具有补肾阳、益精血、润肠道之功效,用于治疗肾阳虚衰、 精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便 秘; 黑芝麻,性味:味甘、性平,具有补益肝肾、养血益精、润肠通便之功效,用于治疗肝肾不 足所致的头晕耳鸣、腰脚痿软、须发早发、肌肤干燥、肠燥便秘、妇人乳少、痈疮湿疹、风癞疬 疡、小儿瘰疬、汤火伤、痔疮等症; 桑葚,性味:甘、酸、寒,具有补血滋阴、生津润燥之功效,用于治疗眩晕耳鸣、心悸失眠、 须发早白、津伤口渴、内热消渴、血虚便秘等症; 麦冬,性味:甘、微苦、微寒,具有养阴生津、润肺清心之功效,用于治疗肺燥干咳、虚痨 咳嗽、津伤口渴、心烦失眠、内热消渴、肠燥便秘、咽白喉等症。
[0014] 本发明药物是基于中医治疗便秘的原则,从依据便秘的病理机制及药理作用认 为:就便秘,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效 果。
具体实施方式
[0015] 本发明就是针对上述便秘的治疗而提出的一种中药配方,采用该配方制备的药物 药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体 实施方式作进一步详细的描述: 实施例1: 一种可有效治疗便秘的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如 下所示: 竹茹95g、生地黄280g、山楂115g、木香120g、厚朴95g、红花95g、桃仁120g、槟榔120g、生 首乌2〇Og、太子参280g、广陈皮80g、阿胶95g、当归130g、肉苁蓉120g、黑芝麻120g、桑葚 13(^、麦冬120〖,淀粉适量。
[0016] 实施例2: 一种可有效治疗便秘的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如 下所示: 竹茹105g、生地黄330g、山楂130g、木香140g、厚朴105g、红花105g、桃仁I40g、按榔 140g、生首乌230g、太子参310g、广陈皮90g、阿胶105g、当归150g、肉苁蓉I40g、黑芝麻 140g、桑葚150g、麦冬140g,淀粉适量。
[0017] 实施例3: 一种可有效治疗便秘的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如 下所示: 竹茹120g、生地黄380g、山楂150g、木香160g、厚朴120g、红花120g、桃仁160g、槟榔 160g、生首乌260g、太子参360g、广陈皮100g、阿胶120g、当归180g、肉苁蓉160g、黑芝麻 160g、桑葚180g、麦冬160g,淀粉适量。
[0018] 典型病例 经临床诊断治疗便秘患者共1200例,年龄为55岁以上的750例,只有450例为55岁以下。 1200例患者中痊愈的1120例,有效的80例。总有效率达100%。
Claims (3)
1. 一种可有效治疗便秘的丸剂药物,其特征在于,所述药物的各个组分及其质量份比 如下所示: 竹茹5〇〜120g、生地黄100〜38〇g、山楂90〜i5〇g、木香80〜I60g、厚朴30〜120g、红花 30〜120g、桃仁80〜160g、模榔60〜160g、生首乌1〇〇〜260g、太子参100〜360g、广陈皮30 〜l〇〇g、阿胶30〜120g、当归80〜180g、肉灰蓉l〇〇〜16〇g、黑芝麻90〜160g、桑®90〜180g、 麦冬60〜160g,淀粉适量。
2. 根据权利要求1所述的可有效治疗便秘的丸剂药物,其特征在于,所述药物的各个组 分及其质量份比如下所示: 竹如58〜105g、生地黄115〜330g、山檀1〇〇〜]_3〇g、木香90〜140g、厚朴36〜105g、红花 38〜l〇5g、桃仁9〇〜l4〇g、槟榔7〇〜14〇g、生首乌115〜230g、太子参115〜31〇g、广陈皮38 〜90g、阿胶38〜105g、当归90〜150g、肉苁蓉115〜I40g、黑芝麻100〜140g、桑葚100〜 15(^、麦冬70〜14(^,淀粉适量。
3.根据权利要求1至2所述的可有效治疗便秘的丸剂药物,其特征在于,所述药物的各 个组分及其质量份比如下所示: 竹苑%g、生地黄28〇g、山楂11化、木香口叫、厚朴%g、红花9Sg、桃仁UOg、槟榔12〇g、生 首乌200g、太子参280g、广陈皮8〇g、阿胶95g、当归1:3〇g、肉苁蓉丨2^、黑芝麻12〇g、桑葚 13(^、麦冬12(^,淀粉适量。
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