CN106805218A - A kind of Huangjingzi Qufengjiebiao chewable tablet and its preparation method - Google Patents

Abstract

A fructus Viticis negundo chewable tablet of dispelling pathogenic wind and relieving exterior syndrome and its preparation method, relate to a health care chewable tablet, is made according to the following weight part by raw materials, fructus Viticis negundo 25-30, 20-25 of herba Equiseti Arvinsis, 15-20 of fructus Akebiae, 15-18 of fructus evodiae, 10-15 of folium Artemisiae Argyi, 10-12 of herba polygoni hydropiperis, 5-8 of cliff monkshood, 3-5 of cortex Linderae Fragrantis, 40-50 of powder of miscellaneous grain crops, 50-60 of concentrated fruit juice, 3-5 of supplementary product, said supplementary product is made according to the following weight part by raw materials, pectase 0.5-0.9 part, crystal sugar 1-2 parts, mannitol 0.5-0.7, citric acid 0.3-0.6 part, xanthan gum 0.7-0.8 part; the preparation process comprises the following specific steps: (1) sorting and weighing; (2) preparing a mixed solution; (3) preparing concentrated juice; (4) preparing coarse cereal powder; (5) preparing auxiliary materials; (6) granulating and tabletting, the product is natural and nontoxic, and has the effects of dispelling wind, relieving exterior syndrome, dispelling wind and dispelling cold.

Description

A kind of Huangjingzi Qufengjiebiao chewable tablet and its preparation method

technical field

The invention relates to a chewable tablet for health care, in particular to a chewable tablet of huangjingzi Qufengjiebiao and a preparation method thereof.

Background technique

Traditional Chinese medicine believes that colds are generally related to the feeling of wind evil, which is a syndrome of exogenous pathogenic factors, and is generally treated with expelling wind and relieving the exterior. Expelling wind refers to taking traditional Chinese medicine to regulate the discomfort of the body. Wind is mainly divided into internal wind and external wind. The human body suffers from blood deficiency or dryness due to blood loss and blood consumption. Dizziness is caused by internal wind. To solve the table refers to the release of the certificate. Any drug that can relieve the surface of the skin, induce sweating, and relieve symptoms is called an anti-surface drug. Most of the external medicines have a pungent taste, and the pungent energy can disperse, which can induce the patient to sweat, so that the exogenous pathogens can be released from the sweat, and the external syndrome can be relieved. The focus of expelling wind and expelling the exterior is on expelling wind, and the emphasis is on dispelling wind evil.

At present, there are many kinds of wind-dispelling and external-dispelling medicines on the market, but most of them are slow to take effect, and drowsiness often occurs after taking them, which is not conducive to people's life.

Contents of the invention

The object of the present invention is to provide a Huangjingzi Qufengjiebiao chewable tablet capable of dispelling wind and relieving exterior surface, soothing liver and regulating qi, promoting qi and relieving pain and a preparation method thereof.

The object of the present invention is achieved through the following technical solutions:

A chewable tablet of Vitex japonica for expelling wind and expelling the exterior, made of raw materials according to the following parts by weight: 25-30 parts of Vitex violet, 20-25 parts of Vitex chinensis, 15-20 parts of August root, 15-18 parts of Eguna officinalis, and 10 parts of Artemisia argyi -15 parts, 10-12 parts of Polygonum spicosa, 5-8 parts of Yaxiang, 3-5 parts of mountain yellow bark, 40-50 parts of miscellaneous grain powder, 50-60 parts of concentrated fruit juice, 3-5 parts of auxiliary materials; the auxiliary materials, The raw materials are prepared according to the following parts by weight: 0.5-0.9 parts of pectinase, 1-2 parts of rock sugar, 0.5-0.7 parts of mannitol, 0.3-0.6 parts of citric acid and 0.7-0.8 parts of xanthan gum.

Said Vitex Qufeng Jiebiao Chewable Tablets, the raw materials are according to the optimal parts by weight, 30 parts of Vitex Vitex, 23 parts of Vitex, 15 parts of August Zha, 15 parts of Wuguoguo, 13 parts of Artemisia argyi, 10 parts of Polygonum japonica, 8 parts of incense, 4 parts of mountain yellow skin, 45 parts of miscellaneous grain powder, 60 parts of concentrated fruit juice, and 4 parts of auxiliary materials.

Said Vitex Radix Qufeng Jiebiao Chewable Tablet contains 10 parts of chestnuts, 13 parts of millet, 8 parts of sweet potatoes and 12 parts of sorghum as raw materials in the miscellaneous grain powder according to the optimum weight parts.

Said Vitex Radix Qufeng Jiebiao Chewable Tablet contains 15 parts of pineapple, 10 parts of blueberry, 12 parts of hawthorn and 14 parts of lemon as raw materials in said concentrated fruit juice according to the optimum weight parts.

Said Vitex Radix Qufeng Jiebiao Chewable Tablet, the raw materials in the auxiliary materials are 0.7 parts of pectinase, 1.5 parts of rock sugar, 0.6 parts of mannitol, 0.5 parts of citric acid and 0.7 parts of xanthan gum in the optimal parts by weight.

The preparation method of said a kind of Huangjingzi Qufengjiebiao chewable tablet comprises the following steps:

(1) Sorting and weighing:

Select Vitex japonica, Vitex chinensis, August leaves, Egonia fruit, Artemisia argyi, Polygonum punctatus, Yaxiang, phoenix bark, miscellaneous grains, and fruits, put them into the washing machine, wash them for 2-3 times, air-dry the surface moisture, according to parts by weight, weighing, standby;

(2) Prepare the mixture:

Take the washed Vitex japonica, Vitex chinensis, August berry, ebony fruit, mugwort leaves, Polygonum japonica, Yaxiang, and phoenix bark, cut into slices, strips, or shreds, add 5-8 times the water, and cook on high heat for 0.5-1 hour , then adjust to medium heat and cook for 2-3 hours, filter to get the first decoction, and use the residue for later use; take the residue, add 2-3 times of water, cook on medium heat for 1.5-2.5 hours, filter to get the second decoction ; Combine the two decoctions to obtain a mixed solution;

(3) Preparation of concentrated juice:

Take fresh and plump fruit, wash, peel and remove the core, add 2-3 times of pure water, squeeze the juice, add pectinase, enzymolyze at 40-45°C for 15-25 minutes, and filter to obtain juice; take the juice, Carry out vacuum concentration to obtain concentrated fruit juice with a moisture content of 12-15%;

(4) Preparation of miscellaneous grain powder:

Take miscellaneous grains, wash and dry the surface moisture, bake in microwave until fully cooked, cool to room temperature, carry out vacuum drying, take the dried miscellaneous grains, ultrafinely pulverize them to 200-260 mesh, and obtain miscellaneous grain powder;

(5) Preparation of auxiliary materials:

According to parts by weight, rock sugar and mannitol are taken, crushed to 80-100 meshes, then added with citric acid and xanthan gum and mixed evenly to obtain auxiliary materials;

(6) Granulation and tableting:

Take miscellaneous grain powder, put it into a blender, stir at a medium speed, and at the same time spray the mixed liquid and concentrated fruit juice evenly on the mixed powder, after mixing and preparing, add auxiliary materials, mix evenly, and then granulate through a wet granulator to obtain whole grains; Whole grains, dried at high temperature, then pressed into tablets, and the tablets were sterilized by ultraviolet rays to obtain finished products.

The medicine proportioning of the present invention is derived from the dialectical thought of "strengthening the body" and "coordinating yin and yang" in traditional Chinese medicine. The inventor has devoted himself to the study of Chinese medicine and based on practical experience, selected traditional Chinese medicines, scientifically proportioned, carefully processed.

Among the raw materials, Vitex chrysalis, expels wind and relieves exterior syndrome, relieves cough and asthma, regulates qi, eliminates food and relieves pain, treats cold, cough, asthma, stomach pain and acid regurgitation, indigestion, food accumulation and diarrhea, cholecystitis, gallstones, hernia; , diuresis, eyesight; August Zha, soothes the liver and regulates qi, promotes blood circulation and relieves pain, relieves restlessness and diuresis; Egocarpa fruit, regulates qi and relieves pain, dispels wind and cold; Artemisia argyi, warms meridians to stop bleeding, dispels cold and relieves pain; Polygonum spicosa, detoxifies, dispels dampness, Dispelling blood stasis, hemostasis; Yaxiang, promoting qi and relieving pain, warming the middle and relieving vomiting; Shanhuangpi, dispersing wind and cold, promoting qi and relieving pain, dehumidifying and reducing swelling; miscellaneous grain powder, rich in nutrition, can effectively prevent and improve physical diseases, maintain viscera Normal activities of tissues and organs; concentrated fruit juice, which can not only supplement the vitamins needed by the body, but also improve the taste of chewable tablets and make them taste better.

In the process, the invention takes the cleaned Chinese medicine raw materials, decocts them repeatedly, and combines the extracts to obtain a mixed solution; takes fresh fruits, squeezes the juice, enzymatically hydrolyzes, and concentrates to obtain concentrated juice; selects miscellaneous grains to bake and grind to obtain Cooked miscellaneous grains powder: Spray the mixed liquid and concentrated fruit juice evenly on the miscellaneous grains powder, then add auxiliary materials, make whole grains through a wet granulation machine, press into tablets after high-temperature drying, and finally sterilize with ultraviolet rays to obtain the finished product.

Beneficial effects of the present invention: the Vitex Radix Qufeng Jiebiao chewable tablet of the present invention contains rich nutritional elements and can be eaten for a long time.

The technological advantage of the present invention is that the technological process is simple, easy to operate, and the technological process is scientific, which will not cause the loss of nutritional elements in the raw materials.

The present invention is through two groups of clinical verifications, wherein one group is the treatment group, eats the present invention, eats the present invention once a day, 7 days is a course of treatment, another group of control group takes Qufeng Jiebiao Capsules, takes once a day, 7 days is a course of treatment. For one course of treatment, 100 outpatients were selected for each group, including 30 males and 70 females. The oldest age was 75 years old, and the youngest age was 25 years old. The clinical manifestations were fever, cough, dizziness, low-grade fever, and headache. Control data for:

Table 1 Comparison of two groups of courses of treatment before and after taking (unit: person)

There are obvious differences in the effective rate between the treatment group and the control group, and it is not difficult to see the significant curative effect of the present invention in clinical application.

detailed description

The present invention will be described in further detail below in conjunction with specific embodiments.

Example 1

A chewable tablet of Vitex japonica for expelling wind and expelling the exterior, made of raw materials according to the following parts by weight: 25-30 parts of Vitex violet, 20-25 parts of Vitex chinensis, 15-20 parts of August root, 15-18 parts of Eguna officinalis, and 10 parts of Artemisia argyi -15 parts, 10-12 parts of Polygonum spicosa, 5-8 parts of Yaxiang, 3-5 parts of mountain yellow bark, 40-50 parts of miscellaneous grain powder, 50-60 parts of concentrated fruit juice, 3-5 parts of auxiliary materials; the auxiliary materials, The raw materials are prepared according to the following parts by weight: 0.5-0.9 parts of pectinase, 1-2 parts of rock sugar, 0.5-0.7 parts of mannitol, 0.3-0.6 parts of citric acid and 0.7-0.8 parts of xanthan gum.

Example 2

Said Vitex Qufeng Jiebiao Chewable Tablets, the raw materials are according to the optimal parts by weight, 30 parts of Vitex Vitex, 23 parts of Vitex, 15 parts of August Zha, 15 parts of Wuguoguo, 13 parts of Artemisia argyi, 10 parts of Polygonum japonica, 8 parts of incense, 4 parts of mountain yellow skin, 45 parts of miscellaneous grain powder, 60 parts of concentrated fruit juice, and 4 parts of auxiliary materials.

Example 3

Said Vitex Radix Qufeng Jiebiao Chewable Tablet contains 10 parts of chestnuts, 13 parts of millet, 8 parts of sweet potatoes and 12 parts of sorghum as raw materials in the miscellaneous grain powder according to the optimum weight parts.

Example 4

Said Vitex Radix Qufeng Jiebiao Chewable Tablet contains 15 parts of pineapple, 10 parts of blueberry, 12 parts of hawthorn and 14 parts of lemon as raw materials in said concentrated fruit juice according to the optimum weight parts.

Example 5

Said Vitex Radix Qufeng Jiebiao Chewable Tablet, the raw materials in the auxiliary materials are 0.7 parts of pectinase, 1.5 parts of rock sugar, 0.6 parts of mannitol, 0.5 parts of citric acid and 0.7 parts of xanthan gum in the optimal parts by weight.

Example 6

The preparation method of said a kind of Huangjingzi Qufengjiebiao chewable tablet comprises the following steps:

(1) Sorting and weighing:

Select Vitex japonica, Vitex chinensis, August leaves, Egonia fruit, Artemisia argyi, Polygonum punctatus, Yaxiang, phoenix bark, miscellaneous grains, and fruits, put them into the washing machine, wash them for 2-3 times, air-dry the surface moisture, according to parts by weight, weighing, standby;

(2) Prepare the mixture:

Take the washed Vitex japonica, Vitex chinensis, August berry, ebony fruit, mugwort leaves, Polygonum japonica, Yaxiang, and phoenix bark, cut into slices, strips, or shreds, add 5-8 times the water, and cook on high heat for 0.5-1 hour , then adjust to medium heat and cook for 2-3 hours, filter to get the first decoction, and use the residue for later use; take the residue, add 2-3 times of water, cook on medium heat for 1.5-2.5 hours, filter to get the second decoction ; Combine the two decoctions to obtain a mixed solution;

(3) Preparation of concentrated juice:

Take fresh and plump fruit, wash, peel and remove the core, add 2-3 times of pure water, squeeze the juice, add pectinase, enzymolyze at 40-45°C for 15-25 minutes, and filter to obtain juice; take the juice, Carry out vacuum concentration to obtain concentrated fruit juice with a moisture content of 12-15%;

(4) Preparation of miscellaneous grain powder:

Take miscellaneous grains, wash and dry the surface moisture, bake in microwave until fully cooked, cool to room temperature, carry out vacuum drying, take the dried miscellaneous grains, ultrafinely pulverize them to 200-260 mesh, and obtain miscellaneous grain powder;

(5) Preparation of auxiliary materials:

According to parts by weight, rock sugar and mannitol are taken, crushed to 80-100 meshes, then added with citric acid and xanthan gum and mixed evenly to obtain auxiliary materials;

(6) Granulation and tableting:

Take miscellaneous grain powder, put it into a blender, stir at a medium speed, and at the same time spray the mixed liquid and concentrated fruit juice evenly on the mixed powder, after mixing and preparing, add auxiliary materials, mix evenly, and then granulate through a wet granulator to obtain whole grains; Whole grains, dried at high temperature, then pressed into tablets, and the tablets were sterilized by ultraviolet rays to obtain finished products.

The raw materials and combinations thereof in the miscellaneous grain powder and concentrated fruit juice are only illustrative, but not limited to the above-mentioned raw materials and their combinations, and those skilled in the art can perform equivalent replacements.

Claims (6)

1. a kind of fruit of negundo expels pathogenic wind from the body surface chewable tablets, it is characterised in that：It is made up by following parts by weight of raw material, fruit of negundo 25- 30 parts, meadow pine 20-25 parts, fiveleaf akebia fruit 15-20 parts, trichotomous evodia fruit 15-18 parts, folium artemisiae argyi 10-15 parts, polygonum flaccidum 10-12 parts, precipice perfume 5- 8 parts, Randia cochinchinensis 3-5 parts, coarse cereal powder 40-50 parts, inspissated juice 50-60 parts, auxiliary material 3-5 parts;The auxiliary material, by raw material by following Parts by weight are made, pectase 0.5-0.9 parts, rock sugar 1-2 parts, mannitol 0.5-0.7, citric acid 0.3-0.6 parts, xanthans 0.7-0.8 parts.

2. a kind of fruit of negundo expels pathogenic wind from the body surface chewable tablets according to claim 1, it is characterised in that：Raw material is by optimum weight part Number, 30 parts of fruit of negundo, 23 parts of meadow pine, 15 parts of fiveleaf akebia fruit, 15 parts of trichotomous evodia fruit, 13 parts of folium artemisiae argyi, 10 parts of polygonum flaccidum, 8 parts of precipice perfume, mountain are yellow 4 parts of skin, 45 parts of coarse cereal powder, 60 parts of inspissated juice, 4 parts of auxiliary material.

3. a kind of fruit of negundo expels pathogenic wind from the body surface chewable tablets according to claim 1, it is characterised in that：Raw material is pressed in the coarse cereal powder Optimum weight number, 10 parts of chestnut, 13 parts of millet, 8 parts of Ipomoea batatas, 12 parts of sorghum.

4. a kind of fruit of negundo expels pathogenic wind from the body surface chewable tablets according to claim 1, it is characterised in that：Raw material in the inspissated juice By optimum weight number, 15 parts of jackfruit, 10 parts of blueberry, 12 parts of hawthorn, 14 parts of lemon.

5. a kind of fruit of negundo expels pathogenic wind from the body surface chewable tablets according to claim 1, it is characterised in that：Raw material is by most in the auxiliary material Good parts by weight, 0.7 part of pectase, 1.5 parts of rock sugar, mannitol 0.6,0.5 part of citric acid, 0.7 part of xanthans.

6. a kind of fruit of negundo according to claim 1-5 any one expels pathogenic wind from the body surface the preparation method of chewable tablets, and its feature exists In：Including following operation,

（1）Sorting is weighed：

Fruit of negundo, meadow pine, fiveleaf akebia fruit, trichotomous evodia fruit, folium artemisiae argyi, polygonum flaccidum, precipice perfume, Randia cochinchinensis, coarse cereals, fruit are chosen, cleaning is put into In machine, clean 2-3 times, air-dry top layer moisture, by weight, weigh, it is standby；

（2）Prepare mixed liquor：

Take clean fruit of negundo, meadow pine, fiveleaf akebia fruit, trichotomous evodia fruit, folium artemisiae argyi, polygonum flaccidum, precipice is fragrant, Randia cochinchinensis is cut into slices or bar, thread, 5-8 times of water is added, big fire is decocted 0.5-1 hours, then be adjusted to moderate heat and decocted 2-3 hours, filter to obtain first time decocting liquid, residue is standby With；Residue is taken, adds 2-3 times of clear water, moderate heat to decoct 1.5-2.5 hours, filter to obtain second decocting liquid；Decocting liquid will merge twice, Obtain mixed liquor；

（3）Prepare inspissated juice：

Fresh full fruit is taken, peeling stoning is cleaned, 2-3 times of pure water is added, squeezed the juice, pectase is added, in 40-45 DEG C of bar Digested 15-25 minutes under part, filter to obtain fruit juice；Fruit juice is taken, is concentrated in vacuo, obtain the concentration of moisture 12-15% really Juice；

（4）Prepare coarse cereal powder：

Coarse cereals are taken, is cleaned and is dried top layer moisture, microwave baking is cooled to normal temperature, is vacuum dried to well-done, takes dried Coarse cereals, ultramicro grinding obtains coarse cereal powder to 200-260 mesh；

（5）Prepare auxiliary material：

By weight, rock sugar, mannitol are taken, after being crushed to 80-100 mesh, adds citric acid, xanthans to be well mixed, obtain auxiliary Material；

（6）Granulation, compressing tablet：

Coarse cereal powder is taken, is put into mixer, moderate-speed mixer, while mixed liquor, inspissated juice are uniformly sprayed on mixed powder, is mixed Close after preparing, add auxiliary material, be well mixed, then pelletized through wet granulator, obtain whole grain；Round grain, through high temperature drying after, carry out Compressing tablet, sheet stock obtains finished product through ultraviolet disinfection.