CN106729431A - 一种治疗神经根型颈椎病的温养督脉中药组合物 - Google Patents

一种治疗神经根型颈椎病的温养督脉中药组合物 Download PDF

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CN106729431A
CN106729431A CN201710038776.6A CN201710038776A CN106729431A CN 106729431 A CN106729431 A CN 106729431A CN 201710038776 A CN201710038776 A CN 201710038776A CN 106729431 A CN106729431 A CN 106729431A
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林峰
林一峰
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Lin Chang
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Abstract

本发明涉及中药领域,具体涉及一种治疗神经根型颈椎病的温养督脉中药。该温养督脉中药由下述原料制成:鹿角胶、淫羊藿、葛根、僵蚕、羌活、全蝎、制川乌、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、肉桂、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草。本中药治疗神经根型颈椎病效果明显,无毒副作用。

Description

一种治疗神经根型颈椎病的温养督脉中药组合物
技术领域
本发明涉及中药领域,具体涉及一种治疗神经根型颈椎病的温养督脉中药。
背景技术
颈椎病是指颈椎间盘组织退行性改变及其继发性病理改变累及周围组织结构(神经根、脊髓、椎动脉、交感神经等),并出现相应临床表现者。伴随着社会老龄化、劳动方式的改变、屈颈机遇的增加,颈椎病的发病率较前有明显的提高,己成为影响青、中、老年人的常见病、多发病,因此,防治颈椎病具有非常重要的意义。颈椎病各型占比例中,神经根型占50%-60%。神经根型颈椎病,临床上有称之为痹证型、麻木型或痹痛型颈椎病的,是由于椎间孔处的突出物(椎间盘退变、骨刺等)刺激或压迫脊神经根而导致上肢感觉、运动功能障碍,是颈肩臂痛的常见原因之一。祖国医学并无神经根型颈椎病的病名,神经根型颈椎病根据其临床表现应属于中医学的“痹证”、“颈肩痛”等范畴,与“筋痹”、“骨痹”更为接近。如《内经》有“颈项痛”、“颈项强”等,《伤寒论》有“头项强痛”等。《类证治裁》中也有“肩背痛,不可回顾,此手太阳经气郁不行,宜风药散之”的记载。祖国医学强调辨证论治和整体观念,对疾病有的以主要病机命名,有的以主要症状命名,没有明确提出颈椎病的名称。神经根型颈椎病的病因病机、临床表现以及治疗等散见于“痹证”、“项强”、“头痛”、“颈筋急”、“颈肩痛”等条目之下,如《内经》有’“颈项痛”、“颈项强”’等,《伤寒论》有“项背强万万”、“头项强痛”,《甲乙经》有“肩背痛”、“肩臂痛”等记载,它们的表现都与颈椎病的症状相吻合。又如《灵枢·经脉》中“不可以顾,肩似拔,蠕似折,颈、肩、蠕、臂外后廉痛”及“臂厥”等描述也类似本病的临床表现。《类证治裁》中也有“肩背痛,不可回顾,此手太阳经气郁不行,宜风药散之”的记载。其病因,主要分内因和外因两个方面。一般认为,由于脏腑功能失调,人体气血亏虚,阳气不振,腠理空疏,风寒湿邪得以乘虚侵袭而发病。如《济生方》所说“皆因胶理空虚,受风寒湿气而成痹也”。督脉起于胞中,沿脊背中央而行,贯穿整个脊柱,联系胸腹腔诸脏腑,其别络挟颈两侧而行。揭示该脉与颈椎的密切关系。督脉循行脊背之中,总督诸阳之气,络一身之阳气,又别走太阳,体腔内的脏腑可经由足太阳膀胱经背腰部的腧穴受督脉经气的支配。脊柱乃督脉所过,督脉循行正是脊神经分布区域,“经脉所过,主治所及”,从督脉的起始及循行可以看出,督脉与神经根型颈椎病有密切关系。督脉功能正常,脉气调和,肾主骨生髓机能旺盛,脏腑功能活跃,气血充足,颈椎及四肢得以濡养强壮。若督阳不振,各脏腑功能紊乱,肾不能主骨生髓,骨弱髓枯,精血不足,可导致颈椎及四肢筋脉气血功能失调,引发神经根型颈椎病。督阳不振,温煦无力,脏腑运化失职,水湿痰浊停聚,可痹阻颈部经络;督脉阳虚,气血运行无力,亦可致气滞血瘀,气滞血瘀日久,正气渐衰,腠理空虚,风寒湿邪乘虚而入,内外相搏,血脉凝滞不通,导致经络痹阻,不通则痛,则见颈肩及上肢的疼痛等症状。从以上可以看出,督脉是神经根型颈椎病的经络学基础,神经根型颈椎病的病机与督脉的生理功能、病理变化密切相关。根据“督脉生病治督脉”、“主取督脉,以治四肢病”的理论,以及多年的临床实践,在中医学平衡观、整体观和辨证施治理论的指导下,申请人提出督脉阳虚是神经根型颈椎病最基本的病因病机,风寒湿三气为诱发原因,经络阻滞是重要环节。因而提出治疗神经根型颈椎病的主要原则是温养督脉、通络止痛,从内而治,整体调节,拟定温养督脉方。理论研究表明,从督脉论治该病体现了“治病求本,标本兼治”的原则,且具有一定的整体观,因而更全面、更准确、更科学、更具有中医学特色。前期临床试验证实该方能把握神经根型颈椎病的根本环节,能有效缓解疼痛,改善颈椎功能,且无毒副作用,是一个较理想的防治神经根型颈椎病的中药制剂,具有广阔的应用前景和巨大的社会经济效益。
发明内容
本发明的目的是提供一种治疗神经根型颈椎病的温养督脉中药,本中药治疗神经根型颈椎病效果明显,无毒副作用。
本发明为了实现上述目的,采用的技术解决方案是:
一种治疗神经根型颈椎病的温养督脉中药,由下述重量份配比的原料制成:
鹿角胶3-18、淫羊藿6-15、葛根20-40、僵蚕6-15、羌活6-15、全蝎6-15、制川乌6-12、桂枝6-15、麻黄6-15、猪苓15-30、泽泻15-30、泽兰12-30、莪术6-15、肉桂2-6、细辛2-5、黄芪20-40、当归6-15、没药6-15、枳壳6-15、防风10-20、熟地黄15-30、地龙6-15、红花4-9、甘草4-9。
优选地,鹿角胶6、淫羊藿10、葛根30、僵蚕10、羌活10、全蝎10、制川乌10、桂枝10、麻黄10、猪苓20、泽泻20、泽兰15、莪术10、肉桂3、细辛3、黄芪30、当归10、没药10、枳壳10、防风15、熟地黄20、地龙10、红花5、甘草5。
治疗神经根型颈椎病的温养督脉中药的制备方法如下:
(1)按照上述重量份配比将制川乌与水按照重量比1:10的比例混合,在水中浸泡30分钟;
(2)将所述步骤(1)中的混合物及水煎煮50分钟后,过滤得到第一滤液及滤渣;
(3)按照上述重量份配比将淫羊藿、葛根、僵蚕、羌活、全蝎、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草,混合均匀得到混合物,将该混合物与水按照重量比1:5的比例混合,在水中浸泡30分钟;
(4)将所述步骤(2)和(3)中的混合物混合再煎煮60分钟后过滤得到第二滤液及滤渣;
(5)将所述步骤(4)中所得滤渣与水按照重量比 1:4的比例混合,再煎煮90分钟,最后五分钟时加入肉桂,然后过滤得到第三滤液及滤渣,将第二滤液与第三滤液混合,获得第四滤液;
按照上述重量份配比将鹿角胶烊化入第四滤液中,获得药物的汤剂。
本发明的药理及效果如下:
本发明选取鹿角胶、淫羊藿、葛根、僵蚕、羌活、制川乌、全蝎、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、肉桂、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草等多味中药制成中药汤剂。
其中,鹿角胶,补益肝肾;壮督脉之阳。
淫羊藿,补肾壮阳;祛风除湿;强筋键骨。
熟地黄,补血滋润;益精填髓。
黄芪,健脾补中;升阳举陷;益卫固表;利尿。
当归,补血;活血;调经止痛;润燥滑肠。
葛根,清风寒,净表邪,开腠理。
防风,祛风解表;胜湿止痛;止痉。
制川乌,祛风除湿;温经散寒;止痛。
桂枝,散寒解表;温通经脉;通阳化气。
麻黄,发汗散寒;利水消肿。
羌活,散表寒;祛风湿;利关节;止痛。
僵蚕,祛风止痛,息风止痉,化痰散结。
细辛,祛风散寒;止痛;温肺化饮;通窍。
枳壳,破气;行痰;消积。
猪苓,利尿渗湿。
泽泻,利水渗湿;泄热。
泽兰, 活血祛瘀;行水消肿。
肉桂,补火助阳;引火归源;散寒止痛;活血通经。
没药,散瘀定痛;消肿生肌。
莪术,行气破血;消积止痛。
红花,活血通经;散瘀止痛。
地龙,通络;清热定惊;平喘;利尿。
全蝎,祛风止痉;通络止痛;散结。
甘草,缓急止痛;调和药性。
将上述多味中药原料经过煎煮制备成汤剂,诸药合用,共奏温养督脉、活血祛风、除湿散寒、通络止痛之功。对于治疗神经根型颈椎病效果显著。
临床资料:
为表明本发明药物的治疗效果,本发明经过 120 例神经根型颈椎病患者进行系统的临床研究,120 例病例均来源于广州中医药大学附属骨伤科医院。
治疗组:按就诊顺序根据随机数字表法选取 60 例,在原治疗基础上,停用所有治疗药物,单纯服用本发明药物治疗3个月。
对照组:按就诊顺序根据随机数字表法选取60例,口服扶他林片,治疗3个月。
两组在病情、性别、年龄、病程等方面经统计学处理差异无统计学意义。
服用方法 :治疗组 :每日早晚各一次服用本发明药物的汤剂 300 ml,疗程为 3个月。对照组 :口服口服扶他林片,每次25mg,每天3次,早晨进食前半小时200ml温开水送服,疗程为3个月。
观察指标和方法
参照《中药新药临床研究指导原则》、《中医病证诊断疗效标准》的标准。
治疗组60例,痊愈23例,显效17例,有效18例,无效2例,总有效率为96.67%;对照组60例,痊愈7例,显效20例,有效15例,无效18例,总有效率为70.00%。两组的有效率差异有明显统计学意义,治疗组明显优于对照组。
具体实施方式
实施例1
一种治疗神经根型颈椎病的温养督脉中药,由下述重量份配比的原料制成:
鹿角胶6、淫羊藿10、葛根30、僵蚕10、羌活10、全蝎10、制川乌10、桂枝10、麻黄10、猪苓20、泽泻20、泽兰15、莪术10、肉桂3、细辛3、黄芪30、当归10、没药10、枳壳10、防风15、熟地黄20、地龙10、红花5、甘草5。
治疗神经根型颈椎病的温养督脉中药的制备方法如下:
(1)按照上述重量份配比将制川乌与水按照重量比1:10的比例混合,在水中浸泡30分钟;
(2)将所述步骤(1)中的混合物及水煎煮50分钟后,过滤得到第一滤液及滤渣;
(3)按照上述重量份配比将淫羊藿、葛根、僵蚕、羌活、全蝎、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草,混合均匀得到混合物,将该混合物与水按照重量比1:5的比例混合,在水中浸泡30分钟;
(4)将所述步骤(2)和(3)中的混合物混合再煎煮60分钟后过滤得到第二滤液及滤渣;
(5)将所述步骤(4)中所得滤渣与水按照重量比1:4的比例混合,再煎煮90分钟,后五分钟时加入肉桂,然后过滤得到第三滤液及滤渣,将第二滤液与第三滤液混合,获得第四滤液;
按照上述重量份配比将鹿角胶烊化入第四滤液中,获得药物的汤剂。
实施例2
一种治疗神经根型颈椎病的温养督脉中药,由下述重量份配比的原料制成:
鹿角胶9、葛根30、僵蚕10、羌活10、全蝎6、制川乌10、桂枝10、麻黄10、猪苓20、泽泻20、泽兰15、莪术10、肉桂5、细辛3、黄芪20、淫羊藿10、当归10、没药10、枳壳10、防风15、熟地黄20、地龙10、红花5、甘草5。
治疗神经根型颈椎病的温养督脉中药的制备方法如下:
(1)按照上述重量份配比将制川乌与水按照重量比1:10的比例混合,在水中浸泡30分钟;
(2)将所述步骤(1)中的混合物及水煎煮50分钟后,过滤得到第一滤液及滤渣;
(3)按照上述重量份配比将淫羊藿、葛根、僵蚕、羌活、全蝎、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草,混合均匀得到混合物,将该混合物与水按照重量比1:5的比例混合,在水中浸泡30分钟;
(4)将所述步骤(2)和(3)中的混合物混合再煎煮60分钟后过滤得到第二滤液及滤渣;
(5)将所述步骤(4)中所得滤渣与水按照重量比 1:4的比例混合,再煎煮90分钟,后五分钟时加入肉桂,然后过滤得到第三滤液及滤渣,将第二滤液与第三滤液混合,获得第四滤液;
按照上述重量份配比将鹿角胶烊化入第四滤液中,获得药物的汤剂。
实施例3
一种治疗神经根型颈椎病的温养督脉中药,由下述重量份配比的原料制成:
鹿角胶12、葛根30、僵蚕10、羌活10、全蝎10、制川乌10、桂枝10、麻黄5、猪苓20、泽泻20、泽兰15、莪术10、肉桂5、细辛3、黄芪40、淫羊藿10、当归6、没药10、枳壳10、防风15、熟地黄20、地龙10、红花5、甘草5。
治疗神经根型颈椎病的温养督脉中药的制备方法如下:
(1)按照上述重量份配比将制川乌与水按照重量比1:10的比例混合,在水中浸泡30分钟;
(2)将所述步骤(1)中的混合物及水煎煮50分钟后,过滤得到第一滤液及滤渣;
(3)按照上述重量份配比将淫羊藿、葛根、僵蚕、羌活、全蝎、桂枝、麻黄、猪苓、泽泻、泽兰、莪术、细辛、黄芪、当归、没药、枳壳、防风、熟地黄、地龙、红花、甘草,混合均匀得到混合物,将该混合物与水按照重量比1:5的比例混合,在水中浸泡30分钟;
(4)将所述步骤(2)和(3)中的混合物混合再煎煮60分钟后过滤得到第二滤液及滤渣;
(5)将所述步骤(4)中所得滤渣与水按照重量比1:4的比例混合,再煎煮90分钟,后五分钟时加入肉桂,然后过滤得到第三滤液及滤渣,将第二滤液与第三滤液混合,获得第四滤液;
按照上述重量份配比将鹿角胶烊化入第四滤液中,获得药物的汤剂。
典型病例
病例一:李某,男,56岁,2016年8月18日初诊。病人自述于1年前无明显诱因出现颈部左侧疼痛伴左上肢放射痛,活动受限,在当地医院诊断为“神经根型颈椎病(颈4/5、颈5/6、颈6/7)”。给予对症治疗,症状时轻时重。近日症状加重,来本院诊治。诊见:一般情况好,舌暗、苔薄白,脉弦弱。检查:颈椎生理曲度变直,颈4/5、颈5/6、颈6/7椎间隙旁左侧约1cm处压痛明显,左侧锁骨上窝压痛明显,疼痛向左上肢放射,左侧臂丛牵拉实验(+),压顶实验(+)椎间孔分离试验(+),旋颈试验(-),霍夫曼氏征(-)。左前臂及中、食指麻木,左上肢肌力、肌张力正常,生理反射存在,病理反射未引出,颈椎屈伸活动受限明显。颈椎MRI示颈4/5、颈5/6、颈6/7椎间盘向后偏左突出。申请人认为,本病属督脉阳虚之颈肩痛病,治疗当以温养督脉。处方:鹿角胶6g(烊化)、淫羊藿10g、葛根30g、僵蚕10g、羌活10g、全蝎10g、制川乌10g(先煎)、桂枝10g、麻黄10g、猪苓20g、泽泻20g、泽兰15g、莪术10g、肉桂3g、细辛3g、黄芪30g、当归10g、没药10g、枳壳10g、防风15g、熟地黄20g、地龙10g、红花5g、甘草5g。6剂,每天1剂,水煎服。8月25日复诊:痛减,仍守上方,续服6剂。9月1日复诊:颈痛及左上肢疼痛明显减轻,颈椎活动明显改善。舌淡红、苔薄白,脉弱。仍守上方,续服1月。1月后复诊,颈痛及左上肢疼痛及麻木基本消失,颈椎活动可。

Claims (2)

1.一种治疗神经根型颈椎病的温养督脉中药组合物,其特征在于,由下述重量份配比的原料制成:
鹿角胶3-18、淫羊藿6-15、葛根20-40、僵蚕6-15、羌活6-15、全蝎6-15、制川乌6-12、桂枝6-15、麻黄6-15、猪苓15-30、泽泻15-30、泽兰12-30、莪术6-15、肉桂2-6、细辛2-5、黄芪20-40、当归6-15、没药6-15、枳壳6-15、防风10-20、熟地黄15-30、地龙6-15、红花4-9、甘草4-9。
2.根据权利要求 1 所述的一种治疗神经根型颈椎病的温养督脉中药组合物,其特征在于,所述鹿角胶6、淫羊藿10、葛根30、僵蚕10、羌活10、全蝎10、制川乌10、桂枝10、麻黄10、猪苓20、泽泻20、泽兰15、莪术10、肉桂3、细辛3、黄芪30、当归10、没药10、枳壳10、防风15、熟地黄20、地龙10、红花5、甘草5。
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103417742A (zh) * 2012-05-16 2013-12-04 刘家坤 一种治疗颈椎病和腰椎间盘突出症的中药
CN106237266A (zh) * 2016-09-29 2016-12-21 林峰 一种治疗腰椎间盘突出症的温养督脉中药组合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103417742A (zh) * 2012-05-16 2013-12-04 刘家坤 一种治疗颈椎病和腰椎间盘突出症的中药
CN106237266A (zh) * 2016-09-29 2016-12-21 林峰 一种治疗腰椎间盘突出症的温养督脉中药组合物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘荣顺等: "综合疗法治疗神经根型颈椎病 369 例", 《国医论坛》 *

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